411 results about "Cerebral Thrombus" patented technology

The invention discloses a medicament for treating cerebral thrombus which comprises the following raw materials: white atractylodes rhizome, dried orange peel, root of red rooted saliva, gastrodia tuber, chrysanthemum morofolium ramat, earthworm, safflower, grassleaved sweetflag rhizome, Ligusticum wallichii, peach kernels, polygala root, gum benzoin, licorice root, liquidambar orientalis mill, pericarpium trichosanthis, selfheal, natural musk, wine-treated rhubarb, tortoise shell, natural cow-bezoar, turtle shell, wild chrysanthemum flower, wild jujuba seeds, rhizoma dioscoreae, arborviate seed, capsule of weeping forsythia, spicebush root, malt, medicated leaven, achyranthes and cyathula root, achyranthes root, stellaria root, Arisaema cum Bile, ginseng, scorpion, clerodendroa cyrtophyllum, red ginseng, astragalus root, clematis stem, root of American ginseng, Chinese angelica root, immature bitter orange, lilyturf root and pilose asiabell root.

Medical apparatus and system are provided for preventing and treating diseases by the medical apparatus comprising body-thing, electronic pulse device, medical magnet slices, herbal medicine gauze pads and nano-micro-biochemical-textile. The medical apparatus is made in various types such as cap, eyeshade, waistband, knee-band, wristband based on different position of human body. The medical apparatus and system are effective and safe for preventing and treating diseases such as headache, migraine, eyestrain, nervosas, insomnia, forgetful, overweight, hypertension, diabetes, cerebral thrombosis, cervical spondylosis, lumbago and seraglio, rheumatoic arthritis, scapulohumeral periarthritis.

The invention discloses a compound with thrombolytic activity as well as a preparation method and an application as the thrombolytic agent thereof. The 2-nitrogen or the 3-carboxyl of cyclized dopa is respectively coupled or latticed with H-Ala-Arg-Pro-Ala-Lys-OH, H-Pro-Ala-Lys-OH, H-Arg-Pro-Ala-Lys-OH, H-Gly-Arg-Pro-Ala-Lys-OH or H-Gln-Arg-Pro-Ala-Lys-OH to obtain the compound. The thrombolytic activity of the compound is evaluated by adopting the model of artery-vein bypass cannula thrombus in rats, and the experimental result shows that the compound has the excellent thrombolytic activity and can be clinically used as the thrombolytic agent. The therapeutic action of the compound to the cerebral infarction is further evaluated by adopting the model of cerebral thrombus in rats, and the experimental result shows that the compound has the excellent brain tissue protection action and can be clinically used as the thrombolytic agent.

The medicine for treating coronary heart disease and cerebral thrombus is prepared with motherwort, gingko leaf, astragalus root ginseng, red sage and other over 20 kinds of Chinese medicinal materials in certain weight proportion. It is prepared into medicine powder, capsule, bolus or tablet. It has functions of reducing blood fat, lowering blood viscosity, reducing cholesterol and promoting blood circulation to disperse blood clots, and possesses high curative rate.

A liposome of breviscapine for preparing the medicines to cure cerebral thrombus and coronary heart disease is prepared from breviscapine, phosphatide, cholesterol, and supporting agent chosen from sorbitol, mannitol, cane sugar, sodium chloride, water-soluble starch, etc by different methods. Its advantages are high absorption rate, high biologic utilization rate, and high stability.

The invention discloses an application of sichuan lovage rhizome oil by supercritical CO2 extraction method in pharmacy, which can be used for treating vascular nerve cephalalgia, cerebral thrombus, cerebrovascular angiosclerosis, coronary heart diseases, angina pectoris, hypertension, or asomnia, or common cold, or women's dysmenorrheal.

The invention discloses an oligopeptide modified by 4, 4, 5, 5-tetramethyl-1, 3-dioxy imidazoline-2-benzene-4'-oxygen acetyl and a preparation method thereof and also discloses the application thereof in treating cerebral thrombosis. The preparation method comprises the following step: respectively coupling Ala-Arg-Pro-Ala-Lys, Pro-Ala-Lys, Arg-Pro-Ala-Lys, Gly-Arg-Pro-Ala-Lys or Gln-Arg-Pro-Ala-Lys with the 4, 4, 5, 5-tetramethyl-1, 3-dioxy imidazoline-2-benzene-4'-oxygen acetyl, thus obtaining the compound of the invention. On a rat carotid and jugular bypass cannula thrombosis model, the compound of the invention shows excellent thrombolysis activity. On a rat cerebral thrombosis model, the compound of the invention shows excellent therapeutic effect on cerebral infarction.

The invention belongs to the medication technical field, which discloses the medicine and the preparation method for treating the coronary heart disease and miocardial infarction. The medicine is mainly prepared from ginseng root, dwarf lilyturf tuber, Chinese magnoliavine fruit, radix astragali and Chinese angelica, or ginseng root, dwarf lilyturf tuber, Chinese magnoliavine fruit, radix astragali, Chinese angelica, cassia twig and liquorice, or ginseng root, dwarf lilyturf tuber, Chinese magnoliavine fruit, radix astragali, Chinese angelica, cassia twig, liquorice, danshen root, red peony root, radix notoginseng and safflower, according to certain ratios of weights. The invention can be made to any type of medicament that can be accepted by the clinic or pharmacology, which is the good quality oral preparation. The medicine has effects of Qi-replenishing, Yin-nourishing and pulse-invigorating and blood circulation activating to dissipate blood stasis and lipid lowing, which can be used to curing the chest distress, hard breathe, heart-throb, angina and arrhythmia caused by coronary heart disease and miocardial infarction, the recovery period of the cerebral thrombosis and the sequelae of the cerebral thrombosis, the effects are obvious.

The invention belongs to the technical field of medicine, particularly relates to a Chinese medicinal composition for treating cerebral thrombosis and a preparation method thereof, and aims to overcome the defects of high liver toxicity and poor curative effect of the conventional chemical treatment medicament for treating cerebral thrombosis in the prior art. The Chinese medicinal composition for treating or preventing cerebral thrombosis provided by the invention comprises 10-50 parts of peach seed, 10-20 parts of notopterygium root, 5-20 parts of sophora flower, 5-15 parts of paniculate swallowwort root, 5-10 parts of prepared rehmannia rhizome, 5-15 parts of lily, 5-15 parts of honeysuckle flower, 1-10 parts of red-rooted salvia root, 5-15 parts of barbary wolfberry, 9-15 parts of Indian buead, 9-15 parts of Szechuan lovage rhizome, 5-15 parts of dahurian angelica root, 0.2-9 parts of berberine, 5.5-15 parts of white paeony root, 6-9 parts of rhodiola rosea and 10-15 parts of liquoric root. The Chinese medicinal composition has a very good treatment or prevention effect on cerebral thrombosis, and has a low medicinal side effect and remarkable clinical popularization value.

The invention discloses a traditional Chinese medicine composition for treating cardiovascular and cerebrovascular diseases, which is prepared from the following bulk drugs: leech, lumbricus, scorpio and pseudo-ginseng. The traditional Chinese medicine composition disclosed by the invention accords with the theories of traditional Chinese medicine pharmacology of removing stasis, promoting new and self-quenching wind through blood circulation; in addition, by utilizing the traditional Chinese medicine composition formula, the traditional Chinese medicine composition disclosed by the invention is capable of promoting circulation, removing stasis, removing blood stasis, clearing hematoma, stopping rehaemorrhagia, reducing intracranial pressure, eliminating encephaledema, adjusting whole-body blood, resisting stress reaction and improving microcirculation and has the unique curative effects to perennial serious hypertension, cerebral hemorrhage, stroke, coronary heart disease and cerebral thrombosis.

The invention relates to a drug compound used to treat ischemia cerebrovascular disease, which is formed by panaxoside and bilobalide, wherein, the invention can significantly reduce the infarct size of brain to treat the ischemia condition, cerebral thrombus or the like.

A deacidified ginkgo leaf and its extract are disclosed. The deacidified ginkgo leaf contains flavone glycoside and terpene lactone, but almost not contains alkylphenate of original ginkgo leaf. The flavone glycoside and terpene lactone can be extracted by organic solvent or supercritical CO2 method. The deacidified ginkgo leaf can be used to prepare medicine for preventing and curing coronary heart disease, angine pectoris, cerebral thrombus and cerebral disfunction, health-care food and health-care tea.

The invention discloses an oral preparation of ginkgo leaf total flavonoid aglycone, a preparation method and an application thereof, pertaining to the field of traditional Chinese medicine. Total flavonoid glycosides extracted from ginkgo leaves are hydrolyzed to obtain ginkgo leaf total flavonoid aglycone which is then added with special auxiliary materials for preparing a highly efficient preparation, thereby greatly increasing the bioavailability of the ginkgo leaf total flavonoid aglycone. The preparation has significant curative effects in the treatment of coronary disease, hyperpiesis, cerebral thrombosis, cerebral infarction, apoplexy, dizziness, psychosis, nephritis, bronchitis, Parkinson's disease, diabetes, tumor, leukemia and other diseases.

The invention discloses a Chinese drug for curing sequelae of cerebral hemorrhage, cerebral infarction and cerebral thrombosis, which relates to a Chinese drug for the treatment of cardio-cerebrovascular diseases. The invention solves the problem of high drug dependence on the prior drug for curing the sequelae of the cerebral hemorrhage, the cerebral infarction and the cerebral thrombosis. The Chinese drug for curing the sequelae of the cerebral hemorrhage, the cerebral infarction and the cerebral thrombosis of the invention comprises the drugs calculated according to the amounts by weight that 10 to 20 parts of antelope horn, 15 to 25 parts of whole worm, 10 to 20 parts of uncaria atem with hooks, 15 to 25 parts of batryticated silkworm, 10 to 20 parts of giant typhomium tuber, 15 to 25 parts of cassia twig, 10 to 20 parts of ledebouriella root, 10 to 25 parts of frankincense, 10 to 20 parts of Chinese ephedra, 15 to 30 parts of gastrodia tuber, 3 to 7.5 parts of musk and 15 to 25 parts of Chinese angelica root. The total curative ratio of the Chinese drug for curing the sequelae of the cerebral hemorrhage, the cerebral infarction and the cerebral thrombosis of the invention is 40 percent, the total effective rate is 93.3 percent, and the patient has no drug dependence on the Chinese drug of invention.

The invention discloses a new eucommia bark and mulberry leaf beverage and a preparation method thereof, eucommia bark leaves and mulberry leaves are adopted as the raw materials, and the preparation method comprises the processes of collecting leaves, cleaning, sorting, washing, thermal processing, thermal dissipation and extraction, etc. As the active ingredients of the eucommia bark and mulberry leaf beverage prepared by the invention are increased, the eucommia bark leaves and the mulberry leaves further have the consistent effects of lowering blood pressure, lowering blood lipids, preventing cerebral thrombosis and myocardial infarction, lowering blood glucose, anti-aging, anti-fatigue and enhancing the immunity and the like, the effects of the eucommia bark leaves and the mulberr are overlapped, thereby having very strong compound synergy; furthermore, the eucommia bark leaves have the effects of nourishing liver and kidney, and the mulberry leaves have the effects of dispelling wind, clearing heat, clearing liver and improving eyesight, thereby achieving the complementary effect. The compatibility of the eucommia bark leaves and the mulberr is great, thereby obtaining the balance on the nature and the flavor (the nature and the flavor of the eucommia bark leaves are warm, and the nature and the flavor of the mulberry leaves are cold), leading the health care function to be more prominent and having good market prospect.

The invention relates to a pharmaceutical composition which is developed on the basis of the modern medicine theory and contains bezoar, musk and natural plant extracts or monomers. The composition has good functions of preventing and treating cerebrovascular diseases. Based on the drug combination of bezoar and musk, a plurality of plant drug combinations are added. The pharmaceutical composition has a more substantial curative effect of treating cerebrovascular diseases (including cerebral thrombus, cerebral ischemia, cerebral infarction, traumatic brain injury and the like) than original medicines.

The invention provides 2-hydroxymethyl-3,5,6-trimethylpyrazine derivatives with the structure of a formula (I) or pharmaceutically acceptable salts thereof, relating to the field of related antithrombotic medicines, wherein the definition of R is shown in the specification of the invention. The invention also provides preparation methods of the derivatives or pharmaceutically acceptable salts thereof, medicine compositions and application of the derivatives used as effective components in preparing medicines for treating cerebral thrombosis, cerebral infarction, angina, myocardial infarction and arrhythmia related with thrombus.

The invention discloses a medicine composition for treating cerebral thrombosis as well as the preparation method, comprising the following active pharmaceutical ingredients: notopterygium, rhizoma gastrodiae, long-noded pit viper, chilopod, chrysanthemum, scorpion, pangolin, leech, tabanus, earthworm, calamus, danshen root, storax, benzoin, weeping forsythia nut, herba taxilli, fried eucommia bark, apocynum venetum, safflower, peach nut, root of herbaceous peony, angelica sinensis, woodlouse, pubescent angelica, zaocys dhumnades, fructus liquidambaris, cortex periplocae, herba lycopodii and Chinese starjasmine stem. The medicine composition is made into a preparation accepted clinically according to the conventional craft. The medicine composition has good curative effect for treating cerebral thrombosis.

The invention relates to a preparation method of 24(R)-ocotillol DQ and pharmacal application thereof, belonging to the field of medicines. The preparation method comprises the following steps of: taking 1.0kg of ginsenoside, and adding water for dissolving; adding the dissolved ginsenoside onto a processed macroporous adsorption resin column; eluting with 35-55 percent alcohol until no saponin reacts, and then eluting with 60-90 percent alcohol; after the eluent is evaporated to dryness, adding sodium hydroxide for hydrolyzing, and regulating the pH of a hydrolysate to neutrality; adding the hydrolysate onto a macroporous adsorption resin column AB-8, desalting, and then eluting with 60-90 percent alcohol; and after the eluent is evaporated to dryness, oxidizing and recrystallizing to obtain a product. The invention can be applied to preparing medicaments for preventing and treating brain tissue damages caused by local and global brain ischemia, treating transient ischemic attacks, cerebral thrombosis and cerebral infarctions.

The invention relates to a traditional Chinese medicine preparation for treating coronary heart diseases and angina pectoris, which is characterized by being prepared by grinding ginseng, radix salviae miltiorrhizae, rhizoma ligustici wallichii, astragalus root, Chinese eaglewood, leech, angelica, white atractylodes rhizome, safflower, sandalwood, dalbergia wood, clove, tall gastrodia tuber, mastic, rosa banksiae, cinnabar, white peony root, saltedaconiteroot and longstamen onion bulb after stir-frying into a dry state by using an iron pan, sieving by a sieve of 200 meshes to prepare medicinal powder and capsulating. The invention has better curative effect to the symptoms of cardiodynia, shortness of breath, insomnia, dreaminess, light headedness, body fatigue, impotence and the like caused by the diseases of coronary heart diseases, angina pectoris, rheumatic heart diseases, cerebral thrombus, vascular headache, lung primary heart diseases and the like, has short treating time, convenient application and quick actions of promoting blood circulation, relieving the stasis of blood and alleviating pain, can eliminate the common symptoms by one treatment course and eliminates the symptoms of a patient with serious state of an illness by three treatment courses. At present, the result of the clinical treatment of nearly thousands of various patients of different types with heart diseases shows that the total effective rate reaches more than 98%, and the rate of completely relieving the symptoms reaches more than 85%.

The invention discloses a traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases, which is mainly prepared from the following components in parts by weight: 20-50 parts of leech, 20-30 parts of earthworm, 25-40 parts of chicken's gizzard-membrane, 30-40 parts of rhizoma ligustici wallichii, 30-40 parts of radix salviae miltiorrhizae, 20-30 parts of radix notoginseng, 15-30 parts of safflower, 15-30 parts of Japanese sweetflag, 10-20 parts of TurmericRoot-tuber, 20-30 parts of senega and 10-20 parts of Chinese Ligusticum Rhizome. The traditional Chinese medicine aims at the cardiovascular and cerebrovascular diseases, is mainly used for treating coronary heart diseases, myocardial infarction, cerebral thrombus, cerebral infarction, hemiplegia, aphasia and apoplexy sequelae caused by the stasis of the veins of the heart and the brain and arteriosclerosis and can also relieve an adverse reaction occurring in the recovery period of cerebral hemorrhage. The clinical application of many years proves that the cure rate of the traditional Chinese medicine for treating the cardiovascular and cerebrovascular diseases reaches 63%, the total effective rate reaches 95%, and the traditional Chinese medicine has obvious effect and better popularization and application prospect.

The invention discloses a non-oral preparation of kudzuvine root total aglycon, a preparation method and an application thereof, pertaining to the field of traditional Chinese medicine. Total glycosides extracted from kudzuvine roots are hydrolyzed to obtain total aglycon which is then added with special auxiliary materials for preparing a highly efficient preparation, thereby greatly increasing the bioavailability of the kudzuvine root total aglycon. The preparation has significant curative effects in the treatment of cardiovascular diseases, hyperpiesis, cerebral thrombosis, headache, diabetes, climacteric syndrome and tumor.

The present invention discloses a Chinese herbal preparation for curing gore blocking and vessel obstruction and a preparation method thereof. The Chinese herbal preparation is prepared with radix salviae miltiorrhizae, suberect spatholobus stem, radix curcumae, frankincense and myrrh according to a certain proportion. Compared with the prior art, the Chinese herbal preparation provided by the present invention is used to cure angitis, scleriasis and arteriosclerotic lower extremity blood vessel obliteration which are caused by gore blocking and vessel obstruction, and moreover, the Chinese herbal preparation also has remarkable therapeutic effect on coronary heart disease and cerebral thrombosis sequela. The Chinese herbal preparation has the advantages of reasonable formulation, notable curative effect and no toxic side effects.