48 results about "Arterial stenosis" patented technology

A method and system for automated decision support for treatment planning of arterial stenoses is disclosed. A set of stenotic lesions is identified in a patient's coronary arteries from medical image data of the patient. A plurality of treatment options are generated for the set of stenotic lesions, wherein each of the plurality of treatment options corresponds to a stenting configuration in which one or more of the stenotic lesions are stented. For each of the plurality of treatment options, predicted hemodynamic metrics for the set of stenotic lesions resulting from the stenting configuration corresponding to that treatment option are calculated.

A method and system for prediction of post-stenting hemodynamic metrics for treatment planning of arterial stenosis is disclosed. A pre-stenting patient-specific anatomical model of the coronary arteries is extracted from medical image data of a patient Blood flow is simulated in the pre-stenting patient-specific anatomical model of the coronary arteries with a modified pressure-drop model that simulates an effect of stenting on a target stenosis region used to compute a pressure drop over the target stenosis region. Parameter values for the modified pressure-drop model are set without modifying the pre-stenting patient-specific anatomical model of the coronary arteries. A predicted post-stenting hemodynamic metric for the target stenosis region, such as fractional flow reserve (FFR), is calculated based on the pressure-drop over the target stenosis region computed using the modified pressure-drop model.

A method is proposed that identifies and quantifies stenoses in arteries based on an analysis of Doppler frequency shifts from several heartbeats. It is non-invasive and individual insensitive. Pulsatile flow through a blood vessel with wall roughness and/or variable lumen area generates flow disturbances, which lead to variations in the shape of the Doppler shift frequency spectrum. One or several frequency bands that are affected by these flow disturbances are selected from the overall Doppler shift frequency spectrum. Next, one or several parameters, which characterize the selected frequency bands and vary with the degree of stenosis, are used in a linear function to calculate the percentage of lumen area reduction. This method applies in the clinically important range of lumen area reduction of 10-70% with a standard error of 5% or less. For lumen area reductions greater than about 70%, the standard error is larger. A system for practical implementation is also proposed.

The present invention relates to minimally invasive X-ray guided interventions, in particular to an image processing and rendering system and a method for improving visibility and supporting automatic detection and tracking of interventional tools that are used in electrophysiological procedures. According to the invention, this is accomplished by calculating differences between 2D projected image data of a preoperatively acquired 3D voxel volume showing a specific anatomical region of interest or a pathological abnormality (e.g. an intracranial arterial stenosis, an aneurysm of a cerebral, pulmonary or coronary artery branch, a gastric carcinoma or sarcoma, etc.) in a tissue of a patient's body and intraoperatively recorded 2D fluoroscopic images showing the aforementioned objects in the interior of said patient's body, wherein said 3D voxel volume has been generated in the scope of a computed tomography, magnet resonance imaging or 3D rotational angiography based image acquisition procedure and said 2D fluoroscopic images have been co-registered with the 2D projected image data. After registration of the projected 3D data with each of said X-ray images, comparison of the 2D projected image data with the 2D fluoroscopic images—based on the resulting difference images—allows removing common patterns and thus enhancing the visibility of interventional instruments which are inserted into a pathological tissue region, a blood vessel segment or any other region of interest in the interior of the patient's body. Automatic image processing methods to detect and track those instruments are also made easier and more robust by this invention. Once the 2D-3D registration is completed for a given view, all the changes in the system geometry of an X-ray system used for generating said fluoroscopic images can be applied to a registration matrix. Hence, use of said method as claimed is not limited to the same X-ray view during the whole procedure.

The invention discloses a congenital heart disease surgical saccule dilating catheter special for children. The heart disease surgical saccule dilating catheter special for children comprises a wire guide port, a water injection port, a fixed sleeve, an outer catheter, an inner catheter, a saccule and a guide wire; the rear end of the saccule is fixed on the outer wall of the front end of the outer catheter; the front end of the saccule is fixed on the outer wall of the front end of the inner catheter; a cavity which is formed by the inner catheter and the outer catheter is communicated with the water injection port; the guide wire is inserted into the inner catheter; the saccule is a small saccule which has a shape of a waist drum and of which the middle part is thick and two heads are thin; the total length of the saccule is 15 to 20mm; the diameter of each of two ends of the saccule is 15 to 20mm; the diameter of each of two heads of the saccule is 8 to 20mm; and the diameter of the middle part of the saccule is 2/3 to 4/5 the diameter of each of the two heads. The diameter of the middle part of the saccule is smaller than that of each of two heads, so the saccule can be accurately positioned on the narrow part of an artery and does not slip; the outer catheter is provided with scale marks to ensure accurate positioning; the chance that a patient suffering from pulmonary stenosis is damaged when the saccule is dilated can be obviously reduced, and safety of straight open thoracotomy is higher. The blank of the saccule dilating catheter special for the children at present is filled.

Linking Magnesium ions to Nitric Oxide precursor L-Arginine, chemically 2-amino-5-guanidino valeric acid, with a platelet aggregation inhibitor compound such as, but not limited to acetylsalicylic acid or clopidogrel bisulfate, unexpectedly results in a pharmaceutically stabilized compositions with extended shelf life to be taken orally to provide gradual release vasodilatory and anti-platelet aggregation pharmacological activity with reduced potential for producing gastrointestinal lesions. L-Arginine releases ADNO (Arginine derived Nitric Oxide) in the coronary artery epithelium as EDRF (endothelium dependent relaxing factor) to dilate the arteries to promote blood flow to the myocardium, and the platelet aggregation inhibitor such acetylsalicylic acid or clopidogrel and others of this class of drugs inhibits or antagonizes the aggregation adhesion of platelets in the blood stream. Aggregated or clumped blood platelets contribute to arterial stenosis due to formation of atherosclerotic plaques that occlude coronary and other circulatory arteries. In addition to coronary arteries, atherosclerotic plaques can occlude and stenose carotid arteries and femoral arteries due to aggregated or clumped blood platelets, and the subject of this patent discovery will also be of cardiovascular health benefit respectively in preventing carotid cerebrovascular accidents and femoral artery leg circulation disease.

The invention discloses a coronary artery stenosis estimation method, system and device. The method comprises the steps: carrying out the preprocessing of an obtained medical digital imaging and communication DICOM image, and obtaining a DICOM image meeting the requirements; inputting the preprocessed DICOM image into a pre-trained neural network, and outputting a calcified area and a coronary artery area through the neural network; determining a calcified area where the plaque with the maximum diameter is located and a corresponding coronary artery area; calculating the maximum diameter of the calcified area and the corresponding coronary artery diameter, calculating the coronary artery stenosis degree according to the maximum diameter of the calcified area and the corresponding coronaryartery diameter, obtaining the lesion level corresponding to the coronary artery stenosis degree, and outputting the lesion level and the coronary artery stenosis degree.

A biological information displaying apparatus includes: a calculator which is configured to calculate measurement values of parameters based on a plurality of biological signals obtained by an acquiring unit, the parameters including: sclerosis parameters relating to arterial sclerosis; and stenosis and/or occlusion parameters relating to arterial stenosis and/or occlusion; a display which is configured to display information; and a display controller which is configured to produce different radar charts of the sclerosis parameters and the stenosis and/or occlusion parameters, and which is configured to display the measurement values of the parameters on the display, on respective one of line segments that radially extend from a center in each of the radar charts, while plotting each of the measurement values of corresponding parameters at a position that is remoter from the center as a clinical value is worse.

The invention provides a functional evaluation method and system for intracranial vascular stenosis, electronic equipment and a medium, and the method comprises the steps: carrying out the three-dimensional reconstruction of intracranial image data, and obtaining a three-dimensional model of a lesion blood vessel; acquiring specific blood flow parameters of the patient according to the three-dimensional model; calculating hemodynamic parameters of lesion blood vessels based on the patient-specific blood flow parameters; and according to the hemodynamic parameters of the lesion blood vessel, evaluating intracranial vascular stenosis. According to the functional evaluation method for intracranial vascular stenosis, the problem that the intracranial stenosis is inaccurately judged only through the intracranial liability artery stenosis degree in the prior art is solved.

The invention provides a coronary artery stenosis quantification method and device, and the method comprises the steps: building the corresponding relation between the multi-view image features of a coronary artery multi-view medical image and the morphological parameters of coronary artery stenosis through the self-learning capability of an artificial neural network; obtaining current multi-viewimage features of the current coronary artery multi-view medical image of the patient; determining morphological parameters of the current coronary artery stenosis corresponding to the current multi-view image features through the corresponding relationship; specifically, determining the morphological parameters of the current coronary artery stenosis corresponding to the multi-view image features, which includes that the morphological parameters of the coronary artery stenosis corresponding to the multi-view image features identical to the current multi-view image features in the corresponding relation are determined as the morphological parameters of the current coronary artery stenosis. The morphological parameters of coronary artery stenosis are predicted based on multiple perspectives, and the influence of stenosis overlapping with other blood vessels on stenosis quantification is relieved.

Disclosed are methods and compositions for reducing coronary artery stenosis, restoring blood flow to infarcted myocardium, improving myocardial perfusion, reducing heart attacks or other adverse cardiovascular events, or treating symptoms of inadequate myocardial function in a mammal involving administering to the mammal (a) a compound that includes eicosapentaeneoic acid or docosahexaeneoic acid and (b) a cholesterol-lowering therapeutic, combined with dietary restrictions (resulting in aggressive loading of marine lipids), whereby a serum LDL concentration of less than 75 mg/dl (and preferably less than 55 mg/dl) is achieved. One particular method involves administering to the mammal a combination that includes (a) a compound that includes an eicosapentaeneoic or docosahexaeneoic acid (for example, a marine lipid) and (b) a cholesterol synthesis or transfer inhibitor, and which may also optionally include aspirin and/or niacin. The methods and compositions of the invention may also further include a bile acid sequestrant and/or buspirone. Also disclosed are methods for treating heart disease that involve administration of buspirone.

The invention relates to a pulse-beat invigorating and heart protecting oral Chinese medicine decoction, in particular to an oral traditional Chinese medicine decoction for treating coronary heart disease, coronary artery stenosis and infarction by pure traditional Chinese medicine. The invention solves the problems of complex treatment procedure, high pain of patients, trauma and high operation risk. Radix Salviae Miltiorrhizae, Lignum Santali Albi, Rhizoma Chuanxiong, Pheretima, Eupolyphaga Seu Steleophaga, Hirudo, Rhizoma Sparganii, Rhizoma Curcumae, Radix Pseudostellariae, Fructus Crataegi, Spina Gleditsiae, Stigma Croci, Radix Paeoniae Rubra, Semen Persicae and Radix Astragali are adopted in the invention. The pulse-beat invigorating and heart protecting oral Chinese medicine decoction has effects of promoting blood circulation and dispelling blood stasis, dredging collaterals, clarifying and inducing resuscitation, regulating flow of QI and resolving depression, warmly invigorating QI of the kidney, reinforcing the kidney to supplement essence, promoting blood circulation to remove blood stasis, and resolving thrombus, and is used for coronary heart disease, stricture of artery and blockage. By the pulse-beat invigorating and heart protecting oral Chinese medicine decoction, the symptoms of patients can be improved rapidly, thrombi and fatty plaques on the wall of blood vessels are dissolved, blood viscosity is reduced, coronary artery stenosis is relieved or eliminated, thrombi are dissolved, blockage is eliminated, myocardial blood supply and nutrition supply are improved, and cardiac functions are improved. The effective rate reaches 95% or above.

The invention relates to an expansion injection system for preventing and treating arterial stenosis, which comprises a catheter, wherein a guide wire channel and a water injection channel extending in the long axis direction of the catheter are arranged inside the catheter; a first balloon which is wrapped at one end of the catheter, wherein the inner cavity of the first balloon is communicated with the water injection channel, and after the first balloon is filled with water, both ends of the first balloon are tapered structures; a catheter joint which is connected to the other end of the catheter, wherein a water injection port and a medicine injection port are formed in the catheter joint, the water injection channel is communicated with the water injection channel, and a medicine injection port is connected with the puncture guide tube base; a guide wire port which is provided on the catheter joint or the catheter, and is communicated with the guide wire channel; a puncture guidetube which is arranged in the catheter, wherein one end of the puncture guide tube passes through the catheter and is attached to the taped surface of the end close to the first balloon in the long axis direction of the catheter, and the other end of the puncture guide tube extends through the inside of the catheter to connect with the puncture guide tube base; and a puncture needle, wherein the needle tail of the puncture needle is connected with a needle, and passes through the puncture guide tube base. The invention has advantages of guaranteeing the stability of a puncture angle and preventing the balloon from damage effectively.

The anti-embolism carotid artery forming system comprises a stent conveying sheath, a self-expanding stent and a stent propelling catheter, and the stent conveying sheath is provided with a near end, a far end and an inner cavity; the self-expanding stent has an unexpanded state and an expanded state; the stent advancing catheter is provided with a catheter shaft, and an expandable component is installed at the far end of the catheter shaft. The stent delivery sheath is provided with the stent propelling catheter, and the stent propelling catheter is sleeved with a sliding sleeve block matched with the stent propelling catheter. The stent has the beneficial effects that embolism protection can be formed through the integrated expansion stent filter screen during stent implantation of vascular endoplasty for treating carotid artery stenosis, the operation is simple and convenient, and the expansion breathable film expands on the expansion stent filter screen to provide completely reliable blockage of the carotid artery; the expansion breathable film in the stent provides more effective fixation for the expansion breathable film, and catheter operation in subsequent steps is simplified.