5 results about "Thoracic aorta" patented technology

Described herein are pumps that linearly reciprocate to assist with circulating blood within the body of a patient. Red blood cell damage may be avoided or minimized by such linear pump movement. The linearly reciprocating movement may also generate a pulsatile pumping cycle that mimics the natural pumping cycle of the heart. The pumps may be configured to reside at various body locations. For example, the pumps may be situated within the right ventricle, the left ventricle, the ascending aorta, the descending aorta, the thoracic aorta, or the abdominal aorta. In some instances, the pump may be deployed within the venous circulation. In other instances, the pump may reside outside the patient.

The invention belongs to the technical field of medicine, and discloses a thoracic aorta in-situ fenestration and whole-course brain protection integrated device and method. According to the method, a bundling balloon is formed by a plurality of small balloons, the different small balloons are controlled to be inflated or shrunk under pressure relief, and the angle of a puncture needle is adjusted through the bundling balloon catheter. And the far-end protection umbrella covers the cluster balloon catheter and is used for preventing thrombus from escaping to the far end. According to the invention, the bundling balloon composed of a plurality of small balloons is designed, and the angle of the puncture needle is adjusted by controlling the different small balloons to expand by filling or shrink by releasing pressure, so that the time for an instrument to enter a membrane rupture window is greatly shortened, and the positioning accuracy of a membrane rupture point of the covered stent is improved; meanwhile, a far-end protective umbrella is arranged to prevent thrombus and other foreign matters from escaping to the far end.

The application provides application of a carbazole derivative Y16 in preparation of a drug for treating cardiovascular diseases, and belongs to the technical field of medicines.The vasodilatation activity of Y16 is determined by using a rat isolated thoracic aorta tension measurement, and the change of the vasodilatation effect of Y16 under the intervention of various channel inhibitors is observed, and the influence of Y16 on blood pressure is determined by using a rat femoral artery cannulation experiment.The results show that the carbazole derivative Y16 has a good dose-dependent vasodilatation effect, and Y16 also shows a blood pressure lowering effect, so that the carbazole derivative Y16 can effectively treat cardiovascular diseases is disclosed for the first time, the application provides a theoretical basis for obtaining a candidate compound of a drug for treating cardiovascular diseases, and also provides a new selection for a drug for treating cardiovascular diseases in clinic.

Described herein are pumps that linearly reciprocate to assist with circulating blood within the body of a patient. Red blood cell damage may be avoided or minimized by such linear pump movement. The linearly reciprocating movement may also generate a pulsatile pumping cycle that mimics the natural pumping cycle of the heart. The pumps may be configured to reside at various body locations. For example, the pumps may be situated within the right ventricle, the left ventricle, the ascending aorta, the descending aorta, the thoracic aorta, or the abdominal aorta. In some instances, the pump may be deployed within the venous circulation. In other instances, the pump may reside outside the patient.

The invention belongs to the technical field of medicines, and particularly relates to application of a small-molecule antioxidant to alleviation of type 2 diabetes vascular injury. In order to develop an effective scheme for dealing with vascular injury of a diabetic patient, research finds that Lithospermoside can specifically inhibit XO in a cell membrane anchoring state and effectively reduce generation of ROS in thoracic aorta, so that BUN, E-selectin, MDA and UACR are remarkably reduced, meanwhile, the fluorescence intensity of nitrotyrosine staining is inhibited, and the blood vessel injury of the diabetic patient is inhibited. Therefore, vascular endothelial injury under the state of type 2 diabetes accompanied by continuous hyperglycemia is relieved, the antioxidation effect is exerted to slow down vascular injury of diabetes and protect blood vessels, and an effective material basis and a new thought are provided for prevention and treatment of vascular injury of type 2 diabetes.