52 results about "Descending aorta" patented technology

A catheter device is disclosed comprising; an elongate sheath (503) with a lumen and a distal end for positioning at a heart valve (6), an embolic protection device (200) for temporarily positioning in the aortic arch for deflection of embolic debris from the ascending aorta to the descending aorta, said embolic protection device is connectable to a transluminal delivery unit (130) extending proximally from a connection point (131), and having: a frame with a periphery, a blood permeable unit within said periphery for preventing embolic particles from passing therethrough with a blood flow downstream an aortic valve into side vessels of said aortic arch to the brain of a patient, and at least one tissue apposition sustaining unit (300, 350) extending from said catheter, into said aortic arch, and being attached to said embolic protection device at a sustaining point (502), for application of a stabilization force offset to said connection point at said embolic protection device, such as at said periphery, and for providing said stabilization force towards an inner wall of said aortic arch, away from said heart, and in a direction perpendicular to a longitudinal extension of said periphery, when said catheter device is positioned in said aortic arch, such that tissue apposition of said periphery to an inner wall of said aortic arch is supported by said force for improving stability and peripheral sealing. In addition related methods are disclosed.

The percutaneous intervention type axial flow blood pump comprises an impeller assembly, a flexible shaft transmission assembly and a handle assembly, the impeller assembly and the handle assembly are connected through the flexible shaft transmission assembly, the flexible shaft transmission assembly comprises a flexible shaft, a transition sleeve and a protective sleeve, the transition sleeve is connected with a flow guide tail cone of the impeller assembly, and the protective sleeve is connected with the impeller assembly. One end of the protective sleeve is fixed to the inner wall of the transition sleeve, the other end of the protective sleeve is connected with the handle assembly, the handle assembly is provided with an in-vitro micro motor in transmission connection with one end of the flexible shaft, and the other end of the flexible shaft is connected with an impeller rotor of the impeller assembly. The impeller assembly and part of the flexible shaft transmission assembly of the axial flow blood pump are percutaneously implanted into the body of a patient, the handle assembly is located outside the body, and the impeller assembly is kept fixed in the descending aorta through an elastic support of the impeller assembly. The axial flow blood pump adopts an in-vitro micro motor and flexible shaft transmission mode, and the problems that the temperature rise of an axial flow blood pump with a built-in motor is too high, abrasion particles are separated out, and fault inspection is not convenient are solved.

Described herein are pumps that linearly reciprocate to assist with circulating blood within the body of a patient. Red blood cell damage may be avoided or minimized by such linear pump movement. The linearly reciprocating movement may also generate a pulsatile pumping cycle that mimics the natural pumping cycle of the heart. The pumps may be configured to reside at various body locations. For example, the pumps may be situated within the right ventricle, the left ventricle, the ascending aorta, the descending aorta, the thoracic aorta, or the abdominal aorta. In some instances, the pump may be deployed within the venous circulation. In other instances, the pump may reside outside the patient.

The invention relates to the technical field of image processing, and discloses a rapid dynamic PET quantitative parameter imaging method and system based on a linear regression model, a terminal and a storage medium, and the method comprises the steps: constructing a fitting data set and a test data set; constructing a standard Patlak analysis model, and selecting a descending aorta slice dynamic signal as an artery input function; establishing a linear regression model between the early integral value and the late mean value by using the fitting data set; extracting a late mean value of the artery input function from the test data set, and estimating an early integral value corresponding to the late mean value in the test data set by using the optimal linear fitting parameter of the linear regression model; and combining the estimated early integral value with a standard Patlak analysis model to calculate each voxel to obtain a voxel-level Patlak quantitative parameter image. According to the method, parameter images with higher quality are obtained by using fewer dynamic scanning sequences, and short-time dynamic PET quantitative parameter imaging is realized.

Mechanical circulatory supports configured to operate in series with the native heart are disclosed. In an embodiment, a centrifugal pump is used. In an embodiment, inlet and outlet ports are connected into the aorta and blood flow is diverted through a lumen and a centrifugal pump between the inlet and outlet ports. The supports may create a pressure rise between about 40-80 mmHg, and maintain a flow rate of about 5 L / min. The support may be configured to be inserted in a collinear manner with the descending aorta. The support may be optimized to replicate naturally occurring vortex formation within the aorta. Diffusers of different dimensions and configurations, such as helical configuration, and / or the orientation of installation may be used to optimize vortex formation. The support may use an impeller which is electromagnetically suspended, stabilized, and rotated to pump blood.

System, devices and methods for providing a blood-free operative region for aortic arch repair procedures. Various embodiments disclose occlusion of the descending aorta, the innominate artery, the left carotid artery and the left subclavian artery while also providing sufficient perfusion distal of the occluding balloons. Various embodiments disclose performing aortic arch repair procedures while the patient's body temperature is maintained an normothermia (about 36 degrees C to about 37.5 degrees C). Other embodiments disclose performing aortic arch repair procedures while the patient's body temperature is maintained at slight hypothermia (about 30 degrees C to about 34 degrees C).

The present disclosure generally relates to prosthetic implants, prosthetic implant systems, and their methods of use, for example, for treating a dissection. The prosthetic implants contemplated herein comprise an expandable arch support structure comprising one or more expandable branches configured to be placed within one or more vessels. Certain aspects of the disclosure relate to methods for treating a dissection, e.g., an aortic dissection, using said prosthetic implants and implant systems. The methods comprise advancing one or more guidewires into an ascending aorta, a descending aorta, and / or one or more one or more vessels of an aortic root or aortic arch. The methods further comprise exposing one or more components of the expandable arch support structure from a sheath. In some cases, the exposed component is an expandable branch that is advanced into the one or more vessels of the aortic root or aortic arch, thus anchoring the implant to the native aorta.

This invention discloses an automated multi-parameter assessment method, device, and medium for aortic imaging based on three-dimensional images. The method includes acquiring three-dimensional chest CT images and preprocessing them; extracting and optimizing an initial centerline based on the obtained three-dimensional vascular mask; dividing the initial centerline into ascending aorta, aortic arch, and descending aorta segments using the optimized initial centerline and the opening positions of branches on the aortic arch; extracting the average CT value of the adipose tissue surrounding the descending aorta based on the divided descending aorta segments; constructing orthogonal cross sections, performing dimensionality reduction and projection processing on each cross-sectional mask, and calculating the major and minor axes based on the farthest point pairs, outputting the major axis diameter sequence of each cross section; calculating the aortic calcification load, assessing aortic dilation and morphological variations, and evaluating the inflammatory status of the perivascular adipose tissue; and generating a comprehensive report of indicators. This invention fully utilizes existing imaging resources, improving the utilization efficiency and clinical value of medical imaging data.

System, devices and methods for providing a blood-free operative region for aortic arch repair procedures. Various embodiments disclose occlusion of the descending aorta, the innominate artery, the left carotid artery and the left subclavian artery while also providing sufficient perfusion distal of the occluding balloons. Various embodiments disclose performing aortic arch repair procedures while the patient's body temperature is maintained an normothermia (about 36 degrees C. to about 37.5 degrees C.). Other embodiments disclose performing aortic arch repair procedures while the patient's body temperature is maintained at slight hypothermia (about 30 degrees C. to about 34 degrees C.).

The utility model discloses a semi-covered stent applied to treatment of aortic dissection in Glardson's surgery, which comprises a metal framework, the metal framework is provided with a main support section and an auxiliary support section connected to the lower end of the main support section, and the main support section and the auxiliary support section are both constructed into an annular net-shaped structure capable of expanding along the radial direction, a covering film is arranged on the circumferential surface of the main supporting section, and meshes are distributed in the circumferential direction of the auxiliary supporting section after the auxiliary supporting section expands in the radial direction. The intravascular stent has the advantages that the descending aorta can be supported in an omnibearing mode only by being placed in the intravascular stent for one time, and blood supply of spinal cord branch blood vessels cannot be blocked.

This invention discloses a non-invasive method for estimating central aortic pressure (PWV) driven by a vascular tree network, relating to the field of cardiovascular hemodynamic modeling. The method includes: collecting clinical data and scaling the vessel length and reference area; calculating the flow waveforms of the aorta and its branches based on the 4D-Flow MRI velocity field to determine the blood flow distribution ratio; constructing an eight-branch vascular tree network model based on the pressure propagation path from the aorta to the brachial artery; selecting a section on the descending aorta's central axis to calculate the flow waveform and inversely calculating PWV; constructing a dataset using sensitivity analysis and one-dimensional positive problem simulation to pre-train the neural network; performing PINN patient-specific fine-tuning on the model; extracting the aortic pressure waveform using the fine-tuned model, calculating the central aortic pressure value, and outputting patient-specific parameters and distribution results. The input waveform constructed based on non-invasive clinical data in this invention can adapt to different patient-specific differences, significantly improving the model's individualization and clinical compatibility.

The application discloses a rotating speed regulation system for a modular intra-aortic axial flow pump. The system comprises a flow detection device, a controller and a blood pump driver. The flow detection device is connected with the controller and is used for measuring the descending aorta flow. The axial flow blood pump of the modular intra-aortic axial flow pump is connected with the controller via the blood pump driver, and the blood pump driver is used for driving the axial flow blood pump to operate. The controller is used for executing relevant steps to adjust the rotating speed of the axial flow blood pump to the optimal rotating speed operation. The application can accurately regulate the rotating speed of the axial flow blood pump of the modular intra-aortic axial flow pump, so that the axial flow blood pump always operates at the optimal rotating speed, thereby exerting the best blood flow hemodynamic support effect and minimizing the additional harm to the patient.

The invention provides a whole body PET image-based blood input function automatic extraction method and system. The method comprises the following steps: S1, obtaining a maximum intensity projection image of a sagittal plane of an upper body of a patient; s2, performing cardiovascular typical image layer positioning based on the maximum-intensity projection image of the sagittal plane of the upper body to obtain a plurality of cardiovascular typical layer images; s3, descending aorta positioning based on K-means clustering is carried out on the multiple cardiovascular typical layer images, and a descending aorta area selection result is obtained; and S4, extracting a blood input function based on a descending aorta region selection result. According to the method, full-automatic descending aorta blood signal, namely blood input function extraction is achieved, the parameter analysis and imaging efficiency is effectively improved, and more efficient and accurate dynamic PET pharmacokinetic analysis is helped to be achieved.

A method of robotically controlling an interventional device includes: providing an interventional device assembly having a plurality of interventional devices; advancing, in a first mode of operation, a first subset of the plurality of interventional devices into the mouth of the descending aorta in response to movement of a control of the controller, where the first subset of the plurality of interventional devices is connected to the control in the first mode of operation; and switching from the first operating mode to the second operating mode in response to a user input using the controller. Switching from the first mode of operation to the second mode of operation causes a second subset of the plurality of interventional devices to be connected to the control of the controller. The method also includes advancing a second subset of the plurality of interventional devices to the treatment site in a second mode of operation.

The invention discloses an ultrasonic imaging method and an ultrasonic imaging system for a fetus in the middle-late pregnancy period. The method comprises the following steps: S220, obtaining three-dimensional ultrasonic data of the fetus in the middle-late pregnancy period; s230, according to the three-dimensional ultrasonic data, the long axis direction of the body area of the fetus in the middle-late pregnancy period is determined; s540, extracting information of a mid-late pregnancy target feature structure of the fetus from the three-dimensional ultrasonic data, wherein the mid-late pregnancy target feature structure comprises at least one of the following parts: gastric vesicle, spine bone, liver, umbilical vein, descending aorta, inferior vena cava, umbilical cord insertion position, umbilical cord, anterior abdominal wall, bladder, legs, umbilical artery and gallbladder; and S560, extracting at least one abdominal standard section of the fetus in the middle-late pregnancy period from the three-dimensional ultrasonic data according to the information of the long axis direction and the middle-late pregnancy target feature structure, and displaying the extracted abdominal standard section. According to the ultrasonic imaging method and the ultrasonic imaging system, the abdominal standard sections of the fetuses in the middle-late pregnancy period are automatically extracted according to the three-dimensional ultrasonic data collected at a time, a doctor does not need to manually extract the abdominal standard sections one by one, and the efficiency of extracting the abdominal standard sections and the quality of the extracted abdominal standard sections are improved.

The invention relates to a novel aortic stent and a manufacturing method thereof. The novel aorta stent comprises a near-end stent section, a far-end stent section, an arch stent section, a covering film and a keel line, the near-end stent section is used for being implanted into a descending aorta, the far-end stent section is used for being implanted into an ascending aorta, and the arch stent section is used for being implanted into an aortic arch. The arch support section is located between the near-end support section and the far-end support section and connected with the near-end support section and the far-end support section. The covering film covers the near-end stent section and the far-end stent section. Wherein the near-end stent section, the arch stent section and the far-end stent section jointly define a supporting cavity, the covering film has foldability, and the keel line has a pre-bent shape. According to the novel aortic stent, the whole stent can achieve the bending effect in the keel line bending direction, so that the elastic straightening force of the novel aortic stent can be reduced, the flexibility of the novel aortic stent is improved, and complications caused by poor wall attachment are reduced.

The present disclosure generally relates to prosthetic implants, prosthetic implant systems, and their methods of use, for example, for treating a dissection. The prosthetic implants contemplated herein comprise an expandable arch support structure comprising one or more expandable branches configured to be placed within one or more vessels. Certain aspects of the disclosure relate to methods for treating a dissection, e.g., an aortic dissection, using said prosthetic implants and implant systems. The methods comprise advancing one or more guidewires into an ascending aorta, a descending aorta, and / or one or more one or more vessels of an aortic root or aortic arch. The methods further comprise exposing one or more components of the expandable arch support structure from a sheath. In some cases, the exposed component is an expandable branch that is advanced into the one or more vessels of the aortic root or aortic arch, thus anchoring the implant to the native aorta.

This application provides a ventricular assist interventional system, relating to the field of medical device technology, comprising a diaphragm pump, a first catheter, a balloon, and a pneumatic actuator. A balloon for implantation into the descending aorta to assist the heart is disposed on the surface between a bidirectional valve on the first catheter and the proximal end of the first catheter. The distal end of the first catheter is inserted into the ventricle. The balloon is connected to the pneumatic actuator via an air circuit. The proximal end of the first catheter is connected to the blood chamber of the diaphragm pump, and the medium chamber of the diaphragm pump is connected to the pneumatic actuator via an air circuit. A single pneumatic actuator simultaneously drives the diaphragm pump to aspirate or pump blood and to inflate or deflate the balloon. The inflation and deflation cycle of the balloon is synchronized with the diaphragm pumping action, thereby precisely corresponding to the systolic and diastolic phases of the heart. This reduces the number of components used in the ventricular assist interventional system and improves the technical problem of existing ventricular assist interventional systems being bulky and easily increasing the burden on patients.

Methods and devices for supporting circulation. The methods may include positioning a blood pump in the arterial vasculature or the venous vasculature. The methods may include positioning a pump portion of the blood pump in a descending aorta, an inferior vena cava, a renal artery, and / or a renal vein. The methods include delivering a pump portion of a blood pump to a target location and rotating one or more impellers to move blood through the pump portion.

The utility model relates to a magnetic anastomosis aortic arch which comprises four artificial blood vessels and a plurality of second magnetic rings, the anastomotic stoma of each artificial blood vessel is provided with a first magnetic ring, each second magnetic ring is arranged at the broken end of the corresponding human blood vessel, and the first magnetic ring and the second magnetic ring attract each other through the magnetic force of the first magnetic ring and the magnetic force of the second magnetic ring. Connection and anastomosis of the artificial blood vessel and the human blood vessel are achieved. The four artificial blood vessels are an aorta blood vessel, a brachial trunk blood vessel, a left common carotid artery blood vessel and a left subclavian artery blood vessel, and one end of the brachial trunk blood vessel, one end of the left common carotid artery blood vessel and one end of the left subclavian artery blood vessel are sequentially connected on the aorta blood vessel in the direction from the ascending aorta to the descending aorta. And the other end of the brachial trunk blood vessel, the other end of the left subclavian artery blood vessel and the two ends of the aorta blood vessel are anastomotic stomas of the artificial blood vessel. The arcus aortae operation can be simplified, the operation time is shortened, the operation difficulty is reduced, operation wounds are reduced, and the operation effect and safety are improved.

The application aims to provide a blood circulation assisting system capable of generating pulsating blood flow and guaranteeing body functions, comprising a first blood circulation supporting unit located in a heart chamber of a patient and a second blood circulation supporting unit located in a descending aorta of the patient, the first blood circulation supporting unit pumping blood in the heart chamber to the aorta, and the second blood circulation supporting unit generating pulsating blood flow by periodically contracting and expanding to squeeze blood, and partially blocking the blood vessel when expanding. When the second blood circulation supporting unit periodically expands to squeeze blood, it does not completely block the blood vessel, but leaves a part of the blood flow passage, so as to allow part of the blood to pass through, prevent the ascending aorta pressure from suddenly rising, and prevent the blood from flowing back to the left ventricle, and also prevent the second blood circulation supporting unit from moving, so as to guarantee the pulsating effect and prevent unnecessary damage to the inner wall of the blood vessel.

A bidirectional intravascular blood pump system is disclosed for deployment in the descending aorta to improve perfusion in both upper and lower extremities. In some embodiments, the system includes a flexible stent housing containing an inflatable pump chamber and selectively inflatable proximal and distal check valves. In some embodiments, a controller sequences inflation and deflation of the pump components in coordination with the cardiac cycle. In some embodiments, the system capable of dynamically providing flow in opposite directions within the descending aorta to optimize systemic and cerebral perfusion. In some embodiments, the system can direct blood flow in either direction through the aorta by an inflation sequence of the check valves and pump chamber. In some embodiments, one or more bypasses in a check element, stent, and / or formed from selective inflation, enable pressurization of the aortic arch when timed with the closing of the aortic valve.

Described herein are pumps that linearly reciprocate to assist with circulating blood within the body of a patient. Red blood cell damage may be avoided or minimized by such linear pump movement. The linearly reciprocating movement may also generate a pulsatile pumping cycle that mimics the natural pumping cycle of the heart. The pumps may be configured to reside at various body locations. For example, the pumps may be situated within the right ventricle, the left ventricle, the ascending aorta, the descending aorta, the thoracic aorta, or the abdominal aorta. In some instances, the pump may be deployed within the venous circulation. In other instances, the pump may reside outside the patient.

The invention provides an auxiliary ventricular intervention system, which relates to the technical field of medical instruments and comprises a diaphragm pump, a first catheter, a balloon and a pneumatic host. A balloon used for being implanted into the descending aorta to assist the heart is arranged on the surface between a two-way valve on a first catheter and the near end of the first catheter, the far end of the first catheter is used for being inserted into the ventricle, the balloon is connected with a pneumatic host air channel, and the near end of the first catheter is connected with a blood cavity of a diaphragm pump. A medium cavity of the diaphragm pump is connected with a pneumatic host through a gas circuit, the diaphragm pump is driven by the pneumatic host to suck or pump blood and drive the balloon to expand or contract at the same time, and the filling and emptying periods of the balloon are kept synchronous with the blood pumping action of the diaphragm, so that the systolic and diastolic periods of the heart are accurately corresponding; the number of elements used by the ventricular auxiliary intervention system is reduced, and the technical problems that an existing ventricular auxiliary intervention system is large in size, and the burden of a patient is easily increased are solved.

A compliant stent implant is provided for deployment into a descending aorta to reduce the clinical impact of a hardened aorta. The compliant stent implant includes a tubular body extending between a proximal end and a distal end and including a proximal anchoring section terminating at the proximal end and a distal anchoring section terminating at the distal end. Each section is adapted to move from a restricted state to an expanded state. The treatment section is interposed between the proximal anchoring section and the distal anchoring section and is adapted to move from an undeployed state having a first volume to a deployed state having a second volume, where in the undeployed state, the treatment section has an undeployed diameter less than a restricted diameter of the distal anchoring section and the proximal anchoring section in the restricted state, and where in the deployed state, the treatment section has an undeployed diameter less than a restricted diameter of the distal anchoring section and the proximal anchoring section in the restricted state. And wherein the difference between the first volume and the second volume is sufficient to retain 20% to 70% of the volume of blood ejected during constriction.

The application relates to an aortic stent and a manufacturing method thereof. The manufacturing method of the aortic stent comprises the following steps: providing a proximal stent section for being implanted into a descending aorta, a distal stent section for being implanted into an ascending aorta, and an arch stent section for being implanted into an aortic arch; providing a foldable covering film; covering the covering film on the proximal stent section and the distal stent section; providing a keel line with a pre-bent shape; and penetrating the keel line through the proximal stent section, the arch stent section and the distal stent section; wherein the proximal stent section, the arch stent section and the distal stent section jointly define a supporting cavity, the covering film is foldable, and the keel line has the pre-bent shape. The whole stent can be bent along the bending direction of the keel line, so that the elastic straightening force of the aortic stent itself can be reduced, the flexibility of the aortic stent is improved, and the complications caused by poor adhesion are reduced.

The percutaneous intervention type axial flow blood pump comprises an impeller assembly, a flexible shaft transmission assembly and a handle assembly, the impeller assembly and the handle assembly are connected through the flexible shaft transmission assembly, and the flexible shaft transmission assembly comprises a flexible shaft, a transition sleeve and a protective sleeve. The transition sleeve is connected with a diversion tail cone of the impeller assembly, one end of the protective sleeve is fixed to the inner wall of the transition sleeve, the other end of the protective sleeve is connected with the handle assembly, the handle assembly is provided with an in-vitro micro motor in transmission connection with one end of the flexible shaft, and the other end of the flexible shaft is connected with an impeller rotor of the impeller assembly. The impeller assembly and part of the flexible shaft transmission assembly of the axial flow blood pump are percutaneously implanted into the body of a patient, the handle assembly is located outside the body, and the impeller assembly is kept fixed in the descending aorta through an elastic support of the impeller assembly. The axial flow blood pump adopts an in-vitro micro motor and flexible shaft transmission mode, and the problems that the temperature rise of an axial flow blood pump with a built-in motor is too high, abrasion particles are separated out, and fault inspection is not convenient are solved.

A system for treating aortic dissection including an aortic dissection implant comprising an expandable anchoring structure and an elongate tubular structure. The expandable anchoring structure can be configured to apply radial force to the sinuses of the aortic root and / or the sinotubular junction when expanded. The elongate tubular structure can comprise an expandable support frame and one or more layers. The expandable support frame can be configured to extend from the descending aorta to the ascending aorta and curve along with a curvature of the aortic arch when expanded within the aorta. The one or more layers can comprise a first porous layer comprising an atraumatic outer surface positioned over the expandable support frame and a second non-porous layer positioned over a portion of the first porous layer. The second non-porous layer may be configured to be positioned on opposite sides of the aortic dissection and to be inflatable via blood flow to seal against the dissection.

An embolic protection device is disclosed for placement through the descending aorta and over the aortic arch to inhibit emboli release into the aortic side branch vessels while allowing simultaneous access to the aortic valve by at least one interventional and / or diagnostic catheter being introduced from the descending aorta. The filter body comprises a tubular porous mesh material and has an open upstream end to allow entry of blood flow and emboli and an open downstream end to allow entry of multiple catheters. The filter body includes at least one catheter access path parallel to said at least one passage through the filter body, and the filter body has one or more support structures or wires that provide longitudinal stiffness to the device to prevent compression or movement of the filter during a procedure.

Methods and devices for supporting circulation. The methods may include positioning a blood pump in the arterial vasculature or the venous vasculature. The methods may include positioning a pump portion of the blood pump in a descending aorta, an inferior vena cava, a renal artery, and / or a renal vein. The methods include delivering a pump portion of a blood pump to a target location and rotating one or more impellers to move blood through the pump portion.