251 results about "Vascular prosthesis" patented technology

A vascular graft, such as an AAA stent graft, includes a core zone of PET fabric with a non-porous coating comprising a polyurethane, such as Thoralon®, disposed on at least one surface. The coating provides a barrier to prevent short and long term leakage of fluids through the pores of the PET fabric core zone. A method for sealing the pores of a porous PET graft includes the step of coating at least one surface of said graft with at least one polyurethane, or mixtures and combinations thereof. Preferably, the coating is Thoralon®. A method for making a vascular prosthesis includes the steps of providing a core zone of PET fabric, and coating at least one surface of the core zone with at least one polyurethane, or mixtures and combinations thereof, such as Thoralon®. Finally, a method of repairing or treating a defective vessel includes the step of reinforcing or replacing the defective vessel with a graft according to the invention.

A deployment catheter for deploying endoluminal vascular prosthesis that has at least a main graft portion and a first branch graft portion includes an elongate, flexible catheter body having a proximal end and a distal end and comprising an outer sheath and an inner core that is axially moveable with respect to the outer sheath. The catheter includes a main graft restraint that has a main graft release mechanism comprising a plurality of axially spaced restraint members. The catheter further includes a branch graft restraint comprising a branch graft release mechanism.

An instrument for implanting an expandable cylindrical vascular prosthesis includes an outer tube and an inner tube which can be displaced relative to one another. The inner tube is longitudinally slotted on the distal end, at least in an area thereof, and ensheathes the stent with this area which includes the longitudinal slot. In order to implant the stent, the outer tube is retracted. The stent then expands with continuous retracting movement of the outer tube and the inner tube is pressed open along the longitudinal slot. Implantation is terminated, when the outer tube is retracted along the entire length of the stent. The implantation is reversible by pushing the outer tube forward, as long as the stent has not yet fully exited the instrument. In this way, the inner tube is constricted together with the stent, and compressed to an initial position.

A vascular prosthesis comprising a first layer having a predetermined first porosity and a second layer having a predetermined second porosity, wherein the first layer and the second layer are each made of first and second electrospun polymer fibers.

The present invention is directed to a delivery catheter for use in deploying a vascular prosthesis having a self-expanding helical section for use in a wide range of interventional applications. The delivery catheter comprises an elongated member having a helical ledge with a pitch selected to impose a predetermined amount of foreshortening on the vascular prosthesis during deployment. Methods of making and using the delivery catheter of the present invention also are provided.

An elastomeric radiopaque adhesive composition which includes a biocompatible elastomeric matrix and a radiopaque material distributed therein in sufficient amounts to produce a radiopaque image. Further, a hybrid vascular prosthesis including a PTFE structure, a textile structure and a cured elastomeric bonding agent adhesively secures the PTFE to the textile. The elastomeric agent having radiopaque material impregnated therein in sufficient amounts to produce a radiopaque image.

A stent delivery system that helps equalize delivery forces throughout a vascular prosthesis during delivery thereof to an intended treatment site. The delivery system comprises a catheter having a lumen therethrough, an inner core over which the one or more stents or stent grafts is mounted for delivery from the catheter, and an outer sheath overlying the one or more stent or stent graft and the inner core. The inner core of the further comprises a series of outwardly flared members that engage segments or fill voids in or between the stent, stents or stent grafts, respectively. The outwardly flared members of the inner core thus help maintain the segments of the stent or the one or more stents or stent grafts in spaced relation with respect to one another as delivery thereof occurs and as removal of the outer sheath occurs to position the one or more stents or stent grafts at the intended treatment site. The outwardly flared members thus help to distribute delivery forces more evenly throughout the one or more stents or stent grafts being delivered from the catheter. The outwardly flared members further aid accurate placement of the one or more stents or stent grafts by maintaining longitudinal spacing thereof during delivery.

A guidewire assembly for use in deploying a bifurcated endoluminal vascular prosthesis that has a main graft portion and at least a first branch graft portion The guidewire assembly include a hollow guidewire sheath having a restraint mechanism, such as a tubular sheath, for constraining a branch graft portion of the vascular prosthesis and an inner core wire that is slidably insertable into a central lumen of the hollow guidewire sheath. In use, the guidewire assembly may be used with a deployment catheter to deploy the bifurcated vascular prosthesis and leave the inner core wire in position in the patient's aorta, extending through the main graft portion of the vascular prosthesis.

Vascular prostheses and methods of use are provided, wherein the vascular prosthesis includes a plurality of bistable unit cells configured to form a helical structure. A visualization catheter also is provided for use ensuring accurate measurement of a lesion and ensuring delivery and placement of the vascular prosthesis.

The present invention relates a vascular prosthesis and related assembly methods that includes a plurality of modular segments inter-engaged by flexible, and preferably lockable, inter-engageable elements forming joints or other connector areas. The segments may have a number of different mechanical properties and may be assembled by the clinician, through mechanical or chemical joining, to customize the prosthesis for a specific patient or application.

The present invention relates to decellularized vascular prostheses that are resistant to thrombus occlusion and have a low level of immunogenicity. The vascular prostheses are denuded of cells, and coated with an anti-thrombogenic agent and a growth factor that promotes recellularization and further reduces the immunogenicity. The prostheses have high mechanical strength, resist aneurysm rupture, and allow for secure surgical sutures while maintaining structural integrity. The present invention provides vascular prostheses that are blood vessels, valves or portions of vessels containing valves. The present invention is also useful for coating synthetic vascular stents.

Luminal prostheses comprise adjacent expansible segments, typically serpentine ring segments joined by sigmoidal links. By properly orienting the sigmoidal links and aligning hinge regions on adjacent serpentine rings, enhanced performance can be obtained.

A delivery device includes a guidewire catheter and a delivery assembly extending about the guidewire catheter. The delivery assembly includes a locking mechanism that selectively engages a proximal handle of the delivery assembly with a push rod to which a vascular prosthesis is directly or indirectly attached. When an actuator selectively disengages the proximal handle from the handle body, rotation of the proximal handle is independent of longitudinal movement of the vascular prosthesis relative to the handle body, whereby the proximal handle can be moved along the handle body with rotation.

A deployment catheter for deploying an endoluminal vascular prosthesis that has at least a main graft portion and a first branch graft portion. The deployment catheter preferably comprises an elongate, flexible catheter body having a proximal end and a distal end, and an outer sheath and an inner core that is axially moveable with respect to the outer sheath. The catheter preferably comprises a main graft restraint that has a main graft release mechanism comprising a main graft sheath and a suture threaded through a plurality of the openings in the main graft sheath. The catheter further comprises at least one branch graft restraint comprising at least one branch graft release mechanism.

The present invention is directed to a delivery catheter for use in deploying a vascular prosthesis having a self-expanding radial distal section joined to a helical section for use in a wide range of interventional applications. The delivery catheter comprises an elongated member having a balloon disposed adjacent to a distal end of the member, means for engaging the distal section of the vascular prosthesis against axial translation, and a sheath that restrains the vascular prosthesis against the elongated member during transluminal delivery. The balloon also may be used to perform angioplasty of a stenosis located within the vessel prior to deployment of the vascular prosthesis. Methods of using the delivery catheter of the present invention also are provided.

A flat sheet of woven material includes warp yarns and weft yarns interlaced at substantially right angles to each other. A graft material is cut from the flat sheet of woven material such that the graft material includes a graft material longitudinal axis and the warp yarns are disposed at an angle relative to the graft material longitudinal axis. The warp yarns and weft yarns are not parallel to or perpendicular to the graft material longitudinal axis. The graft material is formed into the shape of an endoluminal prosthesis, such as by rolling opposing edges towards each other and securing the opposing edges to each other. The endoluminal prosthesis thus includes warp yarns disposed at an angle relative to the prosthesis longitudinal axis.

With an insertion catheter for inserting a vascular prosthesis into a vessel, with an elongate, substantially tubular catheter cover having a proximal and a distal end, with an outlet for the vascular prosthesis provided at the distal end, in order to make insertion of the vascular prosthesis into the vessel particularly safe and simple, in particular, to provide the vascular prosthesis with protection against twisting, it is proposed that the outlet have a cross-sectional shape differing from a circular shape, and that the cross-sectional area defined by the outlet area be smaller than the cross-sectional area of the vascular prosthesis inserted in the vessel in the opened, unexpanded state.