27 results about "Periprosthetic" patented technology

This invention provides a fixation device and assembly method for pericondylar fractures of the knee joint prosthesis. The knee joint prosthesis includes a femoral condyle, a tibial plateau, and a tibial pad. The femoral condyle includes an anterior condyle, two posterior condyles, and an intercondylar fossa. A fixation device is installed in the intercondylar fossa, comprising an intramedullary fixation pin and a connecting fixation block. The connecting fixation block is installed within the intercondylar fossa and engages with the force-applying end of the intramedullary fixation pin. The connecting fixation block includes a main body with a top surface facing the tibial pad and a bottom surface opposite the top surface. The bottom surface extends away from the top surface to form a protrusion, and a through hole is formed within the protrusion, which is used to accommodate and fix the force-applying end of the intramedullary fixation pin. This invention embeds the entire connecting fixation block within the intercondylar fossa, fully utilizing the existing intercondylar fossa space of the PS-type prosthesis to establish a precise channel for the intramedullary fixation pin, thereby fixing the pericondylar fracture through structural fit.

Periprosthetic bone fixation plates are disclosed including, for example, periprosthetic proximal femur plate, periprosthetic distal femur plate, periprosthetic humerus plate, periprosthetic ring plate, and periprosthetic troch plate. In use, the periprosthetic bone fixation plates are arranged and configured for use in periprosthetic fractures. That is, the periprosthetic plates include one or more features to facilitate positioning and securement of the bone fixation plate to a patients bone that previously received a surgically implanted orthopedic device or implant such as, for example, an intramedullary nail, a hip prosthesis, a knee prosthesis, etc. In use, the one or more features are designed and configured to facilitate avoidance of the previous surgically implanted orthopedic device or implant. In addition, the periprosthetic bone fixation plates are arranged and configured to facilitate plating of a longer working length as compared to existing bone fixation plates (e.g., plating from, for example, femoral condyle to greater trochanter).

FIELD: ophthalmology.SUBSTANCE: used to remove residual cortical masses that have migrated to the equatorial region after cataract extraction (CE) in patients after keratoprosthetics. To do this, the optical cylinder of the keratoprosthesis is unscrewed using a key. Residual cortical masses are visualized through the opening of the optical cylinder (OOC) and removed using a Simcoe cannula or a straight cannula with a flat tip mounted on a 10 ml syringe. The optical cylinder is screwed back in using a key.EFFECT: invention reduces the risk of developing intra- and postoperative complications and accelerates visual rehabilitation of patients by reducing the time of surgical intervention and without performing additional approaches.1 cl, 1 ex

The invention discloses a functional coating for the surface of an orthopedic implant material as well as a preparation method and application thereof, the coating comprises core-shell structure nanoparticles, copper oxide nanoparticles with the particle size of 200nm are taken as a core, and a compound of polydopamine and baicalein is taken as a shell. The preparation method comprises the following steps: dissolving baicalein in ethanol, dispersing copper oxide nanoparticles in water, mixing to obtain a suspension, adding dopamine hydrochloride, adjusting to alkalinity, and immersing the implant material matrix for reaction. The coating is applied to an orthopedic implant material for preventing and treating periprosthetic infection, and the core-shell structure of the coating can realize continuous release of baicalein and intelligent response release of copper ions in an acidic infection environment, so that the synergistic effect of early-stage antibacterial immune regulation and late-stage enhanced antibacterial is exerted; the compound has multiple functions of long-acting antibiosis, biofilm resistance, promotion of M2 polarization of macrophages and reduction of bone destruction.

A reverse bolted greater trochanter periprosthetic plate configured to be mounted to a femur of a patient includes a central portion with an inner surface configured to face and / or contact a femoral surface of the femur; a plurality of leg portions extending from the central portion forming a claw configured to grasp a portion of the femur; and a bolt receptor portion extending from the central portion configured for receiving a bolt for securing the plate to the femur during a reverse bolted greater trochanter periprosthetic procedure.

A computerized system and method (123A-C) for the automated design and additive manufacturing of patient-specific orthopedic reconstructions (600R). The method integrates anatomically tagged medical scans, oriented relative to X, Y, and Z axes, with machine-learning models trained on aggregate historical biomechanical outcomes to generate optimized implant geometries. The system calculates an Osseointegration Probability Score (OPS) and a Comprehensive Prognostic Success Score (CPSS) to dynamically modify internal porous lattice densities, minimizing stress shielding while maximizing load-bearing capacity. The manufacturing process simultaneously generates internal longitudinal conduits for post-operative vascularization and computationally optimized structural anchors (bulges, serrations, and wings) for precise anatomical fixation. By linking real-time biomechanical simulation with prognostic clinical data, the invention provides a high-fidelity manufacturing blueprint that improves long-term implant stability and reduces periprosthetic complications.

The invention discloses a targeted periprosthetic infection detection, drug delivery and drug intervention system as well as a method and application thereof, and belongs to the field of biological medicine. The detection and drug intervention system comprises a micrococcus nuclease sensitive biological probe, a functional silicon plastid for bearing the micrococcus nuclease sensitive biological probe, light-cured hydrogel and an implant, wherein medicines are carried in the functional silica plastid; a micrococcus nuclease sensitive biological probe is connected to the surface of a functional silicon plastid through electrostatic interaction force to obtain a nuclease probe functional silicon plastid, and the nuclease probe functional silicon plastid is connected to the surface of an implant through photocuring hydrogel. According to the system provided by the invention, the detection is realized, the delivery of the medicine is also realized, and the release of the medicine can also be realized when the occurrence of infection around the prosthesis is judged, so that the intervention treatment of the medicine is carried out.

A reverse bolted greater trochanter periprosthetic plate configured to be mounted to a femur of a patient includes a central portion with an inner surface configured to face and / or contact a femoral surface of the femur; a plurality of leg portions extending from the central portion forming a claw configured to grasp a portion of the femur; and a bolt receptor portion extending from the central portion configured for receiving a bolt for securing the plate to the femur during a reverse bolted greater trochanter periprosthetic procedure.

A targeting system is disclosed. In use, the targeting system is configured to target (e.g., aim, locate, etc.) a fastener opening in a bone plate, and more particularly, a variable angle fastener opening formed in a perimeter of a periprosthetic bone plate. In one embodiment, the targeting system includes an alignment guide that includes a plurality of combination slots for targeting a plurality of openings formed in a periprosthetic bone plate. Additionally, the targeting system includes a plug that is configured to be positioned within a combination slot formed in the alignment guide. In use, positioning the plug into the combination slot formed in the alignment guide transforms the combination slot into a generally circular hole or opening having a predetermined trajectory that is aligned with one of the variable angle openings formed in the perimeter of the periprosthetic bone plate, thereby defining a trajectory from the alignment guide to the variable angle opening.

Provided herein is a computer-implemented method including obtaining values for non-modifiable risk factors, each defining an immutable patient characteristic determined to impact a likelihood that a complication results from an arthroplasty procedure. The system obtains first candidate values for modifiable risk factors of the patient defining a mutable characteristic of the patient or the arthroplasty procedure. The first candidate values are determined to minimize the likelihood that the complication results from the arthroplasty procedure. The system obtains second candidate values for the modifiable risk factors of the patient determined to maximize the likelihood that the complication results from the arthroplasty procedure. The system determines a personalized risk interval that represents a range of modifiable risk for the patient with respect to the arthroplasty procedure including determining (i) a lower bound and (ii) an upper bound for the personalized risk interval; and providing an output indicative of the risk interval.

A modular orthopedic implant system configured to interconnect fracture fixation implants with arthroplasty components across multiple anatomic sites. The system incorporates a clothespin-style tapered male stem and a fluted female receiver, forming a secure, fatigue-resistant mechanical interface. This docking feature enables modular coupling between trauma implants such as intramedullary nails and joint replacement constructs including total hip stems, total knee femoral components, total shoulder stems, reverse shoulder humeral components, and ankle arthroplasty tibial components. The modular configuration allows adaptability across anatomical regions, facilitating revision, limb salvage, and periprosthetic fracture stabilization.

This invention provides a gradient silicon nitride ceramic femoral head prosthesis and its preparation method, relating to the technical fields of clinical medicine and biomaterials. The femoral head prosthesis is prepared from 88-94 parts of silicon nitride powder, 4-12 parts of sintering aid, 5-20 parts of tungsten carbide titanium, and 0-30 parts of pore-forming agent, wherein the pore-forming agent cannot be 0 parts. The gradient silicon nitride ceramic femoral head prosthesis of this invention retains the advantages of silicon nitride ceramics—low wear, low friction, high strength, high fracture toughness, and good chemical stability—at the interface between the femoral head prosthesis and the liner, while reducing wear on the titanium alloy femoral stem cone caused by the large hardness difference between the femoral head prosthesis and the liner. This reduces the incidence of organ toxicity, periprosthetic osteolysis, and aseptic loosening caused by metal wear debris, improves the survival rate of the femoral head prosthesis and the femoral stem cone, reduces the revision rate of replacement surgery, and saves patients' treatment costs.

This invention discloses a system and method for predicting the risk of periprosthetic infection after knee arthroplasty, belonging to the field of medical data analysis and processing technology. The system includes: an image acquisition interference detection module, an initial infection area determination module, an infection risk area correction module, and a risk prediction result output module. This invention quantitatively determines the interference of metal artifacts in image acquisition by combining relevant image parameters, ensuring the authenticity and reliability of the input images. Based on this, the initial infection area determination module initially identifies the infection risk area around the prosthesis, and the infection risk area correction module further corrects the initially determined infection area, outputting a more accurate corrected infection risk area. Finally, the risk prediction result output module outputs the final infection risk prediction result based on the corrected dataset. Through the synergistic effect of the above modules, the accuracy of periprosthetic infection risk prediction after knee arthroplasty is significantly improved.

Medical instrumentation for simulation purposes in hip endoprosthetics, characterized by a simulation body (66) that can be tilted about a tilting axis (60) in a spatial reference system, a sensor unit (34) with which the magnitude and orientation of a tilting angle can be detected when the simulation body (66) is tilted, a data processing device (26) and a guidance unit (30), wherein the data processing device (26) is designed and programmed to simulate an inclination of a human pelvis (10) in a body reference system in which the pelvic inlet plane (B) of the pelvis (10) is inclined relative to a frontal plane (F) of the body by the tilting angle, and wherein the data processing device (26) outputs implantation information to the user at the guidance unit (30) that depends on the tilting angle.

Functional patient-specific acetabular component alignment is important in total hip arthroplasty. A method for acetabular component alignment by calculating pelvic tilt from an anteroposterior radiograph of the pelvis of a patient may be replicated intraoperatively for patient-specific alignment. A system for automated generation of the pelvic tilt from an anteroposterior radiograph presented improves the efficacy and accuracy of total hip arthroplasty.

The application provides a knee joint prosthesis periprosthetic fracture fixation device and an assembling method. The knee joint prosthesis comprises femoral condyles, a tibial plateau and a tibial pad. The femoral condyles comprise an anterior condyle, two posterior condyles and an intercondylar fossa. The fixation device is installed at the intercondylar fossa. The fixation device comprises an intramedullary fixation needle and a connecting fixation block. The connecting fixation block is installed in the intercondylar fossa. The connecting fixation block is connected with the force applying end of the intramedullary fixation needle. The connecting fixation block comprises a main body. The main body has a top surface facing the tibial pad and a bottom surface opposite to the top surface. The bottom surface extends in a direction away from the top surface to form a protruding part. A through hole penetrating through the main body is formed in the protruding part. The through hole is used for accommodating and fixing the force applying end of the intramedullary fixation needle. The whole connecting fixation block is embeddedly installed in the intercondylar fossa. The original intercondylar fossa space of the PS type prosthesis is fully utilized to establish a precise channel of the intramedullary fixation needle. The periprosthetic fracture is fixed through structural cooperation.

The present invention relates to a medical bone (10) plate for the treatment of fractures of the distal femur (2) with metaphyseal comminution, periprosthetic fractures, and / or interprosthetic fractures, the bone plate (10) being non-custom fit and non-planar, the bone plate (10) being twisted and having a proximal portion (12), a distal portion (16) and an intermediate portion (14) connecting the proximal portion (12) with the distal portion (16), wherein: a. the distal portion (16) is configured to fit to the distal medial femoral condyle (2a); b. the proximal portion (12) is configured to be aligned with the distal ventral section of the femoral shaft (2b).

A medical implant includes an implant component configured to be implanted in a patient, an electrode array, an energy storage device, a wireless communication interface, and implant circuitry. The electrode array includes sensor electrodes spaced apart on the implant component. The energy storage device, wireless communication interface, and implant circuitry are inside the implant component. The wireless communication interface is configured to communicate with a wireless receiver that is separate from the medical implant. The implant circuitry is operative to supply voltage to at least one of the sensor electrodes to measure electrical and / or chemical characteristics associated with when a biofilm is forming on the implant component, and communicate signaling indicating the electrical and / or chemical characteristics through the wireless communication interface.

The invention discloses a controllable topological structure dynamic bionic coating as well as a preparation method and application thereof, and belongs to the technical field of medical materials. The preparation method comprises the following steps: firstly, constructing JNHDs by ferroferric oxide nanoparticles and silver nanoparticles in a sodium citrate solution through a photo-reduction reaction, then coating the surface with aminated silicon dioxide through a silanization reaction, then carrying out thiolation on a substrate containing a silicon dioxide layer, and finally, incubating PEGylated SiO2 (at) JNHDs and the thiolated substrate together, so as to obtain the silicon dioxide coated JNHDs. And preparing. The dynamic bionic coating constructed by the invention has long-term effectiveness, can damage a biological membrane through mechanical force under the activation of an external electromagnetic field, promotes the mesenchymal stem cells to be differentiated into osteoblasts by activating mechanical force sensitive calcium ion channels on the surfaces of the mesenchymal stem cells, overcomes the defects that a static bionic material cannot actively respond and dynamically intervene in a'surface competition ', and has a good application prospect. Finally, the purposes of preventing and treating periprosthetic infection and promoting prosthesis-osseointegration are achieved.

The invention discloses a dental plaque coloring agent-based color development method for an infected mycoderm around an artificial joint prosthesis. The method comprises the following steps: smearing the dental plaque coloring agent on the surface of the infected artificial joint prosthesis; and observing the existence, maturity and distribution condition of the pellicle on the surface of the artificial joint prosthesis according to the color change of the dental plaque coloring agent. According to the method, the bacterial pellicle on the surface of the artificial joint prosthesis implant is visualized through the dental plaque coloring agent, and the maturity of the pellicle is distinguished. Experiments on animal models and clinical samples prove that the dental plaque staining agent shows a good pellicle detection effect and has a relatively high clinical application value.

Bifurcated endoprosthetic devices, systems and methods are disclosed herein for treating disease of human vasculature. In various embodiments, a bifurcated endoprosthesis includes a trunk portion and a plurality of legs, where the legs are constrained such that they maintain alignment with one another. In some examples, the legs and bifurcation of an endoprosthetic device may be formed by cutting a tubular graft component along a portion of less than its entire circumference in a longitudinally central region, and then folding the tubular graft component along the uncut portion to define two legs, where the uncut portion defines the bifurcation. In some such examples, the folded tubular graft component can be coupled with a tubular trunk component to form the bifurcated endoprosthetic device.

Prosthetic periprosthetic bone plates, including, for example, periprosthetic distal femoral plates, are disclosed. In use, the bone plates are configured for use in periprosthetic fractures. That is, the bone plates include one or more features to facilitate positioning and fixation of the bone plates onto a patient's bone that previously received a surgically implanted orthopedic implant, such as an intramedullary nail, a hip prosthesis, a knee prosthesis, etc. In use, the one or more features are designed and configured to facilitate avoidance of the previously surgically implanted orthopedic implant. Additionally, the bone plates are configured to facilitate percutaneous insertion of the bone plates against the patient's bone while minimizing soft tissue irritation. Additionally and / or alternatively, the bone plates are configured to provide improved contouring to facilitate better positioning of the bone plates against the patient's bone (e.g., better contouring adjacent to the patient's greater trochanter).

The invention relates to the technical field of medical equipment, and discloses a static position occupying device for knee joint periprosthetic infection treatment, which comprises a thighbone position occupying component, a tibia position occupying component and a connecting component, a first articular surface is arranged on one side of the femur occupying component away from the femur; a second articular surface is arranged on the side, close to the proximal tibia end, of the tibia occupying assembly, and the second articular surface is movably connected with the first articular surface through a clamping part; the connecting assembly is arranged between the thighbone occupying assembly and the tibia occupying assembly, and the two ends of the connecting assembly are detachably connected with the thighbone occupying assembly and the tibia occupying assembly correspondingly, so that relative fixation and position adjustment between the thighbone occupying assembly and the tibia occupying assembly are achieved; medicine storage cavities are formed in the femur occupying assembly and the tibia occupying assembly. The spacer can be accurately matched with individual anatomy, and joint stability and tissue safety are guaranteed.

Periprosthetic bone fixation plates are disclosed including, for example, periprosthetic proximal femur plate, periprosthetic distal femur plate, periprosthetic humerus plate, periprosthetic ring plate, and periprosthetic troch plate. In use, the periprosthetic bone fixation plates are arranged and configured for use in periprosthetic fractures. That is, the periprosthetic plates include one or more features to facilitate positioning and securement of the bone fixation plate to a patient's bone that previously received a surgically implanted orthopedic device or implant such as, for example, an intramedullary nail, a hip prosthesis, a knee prosthesis, etc. In use, the one or more features are designed and configured to facilitate avoidance of the previous surgically implanted orthopedic device or implant. In addition, the periprosthetic bone fixation plates are arranged and configured to facilitate plating of a longer working length as compared to existing bone fixation plates (e.g., plating from, for example, femoral condyle to greater trochanter).

A method is described for decontaminating room air by means of a tabletop apparatus (10) (or with dedicated stand) for the processing of metal costume jewelry / goldsmiths or dental prostheses through a LASER beam, wherein a source of UV and / or UV-C radiation irradiates a forced flow (F) of ambient air before it comes out of a casing of the apparatus.

New high-efficiency synergistic antimicrobial composition comprising a combination of Triazolo(4,5-d)pyrimidine derivative together with one antibacterial agent selected from the group consisting of fluoroquinolone and pharmaceutical acceptable salts thereof, tetracycline and pharmaceutical acceptable salts thereof or azole and pharmaceutical acceptable salts thereof. Medical device, biomaterial implants or bioprosthesis comprising the new high- efficiency antimicrobial composition incorporated in a coating or bulk distributed.