15results about How to "Reduce severity" patented technology

The application discloses application of O-acyl-alpha-hydroxy acid compounds in weight loss and lipid reduction, and belongs to the fields of biological medicine manufacturing, biological medicine use and functional food development. The O-acyl-alpha-hydroxy acid compounds can inhibit weight growth of high-fat diet-induced obese model mice and reduce body fat. Compared with GLP-1 receptor weight loss drugs which achieve the effect of reducing weight by inhibiting appetite, the O-acyl-alpha-hydroxy acid compounds are not dependent on appetite inhibition, and can reduce side effects such as gastrointestinal discomfort and muscle loss caused by inhibiting appetite. When combined or sequentially administered with GLP-1 drugs, the O-acyl-alpha-hydroxy acid compounds can maintain or enhance the weight loss effect while improving the side effects caused by GLP-1, and can prevent the risk of significant weight rebound after stopping GLP-1 by maintaining body weight. The application provides a safe and effective new strategy for weight loss and lipid reduction.

The utility model relates to the field of power distribution cabinets, in particular to a power distribution cabinet protection device, which comprises a protection box body, a main body used for providing protection capability for a power distribution cabinet, fixing bolts and reinforcing plates penetrating through two sides of the outer part of the protection box body and used for threaded connection, and outer impact pads are fixedly arranged outside the reinforcing plates. The power distribution cabinet protection device is provided with the reinforcing plate, the outer impact pad, the high-frequency current transformer, the temperature sensor, the inner protection frame, the vacuum arc extinguish chamber and the vacuum fuse switch. The protection box body, the external reinforcing plate and the external impact pad enhance the impact resistance and protection capability of the power distribution cabinet, physical protection is formed outside the power distribution cabinet, then the high-frequency current transformer and the temperature sensor are further arranged on the two sides of the power distribution cabinet components inside the power distribution cabinet body, and the high-frequency current transformer is used for detecting internal circuit faults.

This application relates to ACSS2 inhibitors based on imidazole 3-oxide derivatives and methods of use thereof. The invention relates to novel ACSS2 inhibitors having anti-cancer therapy activity, alcoholism treatment activity, and viral infection (e.g., CMV) treatment activity; compositions and methods of preparation thereof; and uses thereof for treating viral infections, alcoholism, alcoholic steatohepatitis (ASH), non-alcoholic steatohepatitis (NASH), obesity / weight gain, anxiety, depression, post-traumatic stress disorder, inflammatory / autoimmune conditions, and cancers including various types of metastatic, advanced, and drug-resistant cancers.

This invention relates to an intervention strategy for the prevention or treatment of individuals suffering from inflammation-related diseases such as diabetes, autoimmune diseases, inflammatory diseases, or cardiovascular diseases. The intervention strategy preferably involves the administration of chlorinated, fluorinated, or bromine-substituted tryptophan, preferably 6-bromotryptophan, and / or mono-fatty acid-substituted glycerophosphate choline (GPC) or di-fatty acid-substituted glycerophosphate choline (GPC), preferably selected from 1-myristoyl-2-arachidonicoyl-glycerophosphate choline (MA-GPC) and 1-arachidonicoyl-glycerophosphate choline (A-GPC), or any derivatives or functional equivalents thereof. Alternatively, the intervention involves the application of a species of the genus *Desulfovibrio*, preferably selected from *Desulfovibrio piger*, *Desulfovibrio fairfieldensis*, *Desulfovibrio desulfuricans*, *Desulfovibrio indonensis*, *Desulfovibrio alaskensis*, *Desulfovibrio vulgaris*, *Desulfovibrio vietnamensis*, and *Desulfovibrio gigas*.

The invention discloses a braking method of a vehicle, the vehicle and electronic equipment, and belongs to the technical field of vehicles. The braking method of the vehicle comprises the steps that in response to an emergency braking signal of the vehicle, the current turning angle of a steering wheel of the vehicle is obtained; and in response to the situation that the current turning angle meets a first turning angle condition, the pitching angle of a vehicle body of the vehicle is adjusted to a target pitching angle, so that the turning angle of the steering wheel reaches the target turning angle. When it is determined that the vehicle possibly steers in the emergency braking process, the pitching angle of a vehicle body of the vehicle is adjusted to the target pitching angle by means of the coupling relation between the dynamic load and steering of the vehicle so as to correct the rotating angle of a steering wheel to the target rotating angle, and it is guaranteed that the vehicle advances along a straight line in the emergency braking process; therefore, the risk and severity of accidents are reduced.

The invention discloses a power system stability analysis method considering communication time delay and periodic sampling, an augmented bilateral closed-loop functional is constructed, a functional correlation matrix in the functional does not need to meet positive definite definition, and only a functional structure needs to meet the requirements of the closed-loop functional; then, dynamic information of a power system model is fully utilized, and some zero equations containing free matrixes are established; a second-order Bessel-Legendre integral inequality is combined to obtain a power system stability criterion; finally, results of other literatures are compared in case simulation, and the stability criterion obtained through the method has superiority and effectiveness.

The invention provides a current grounding fault direction judgment system and method, and relates to the technical field of fault recognition, and the method comprises the steps: integrating the feature codes of a fault region into a data set through a region module, marking region characters, transmitting the data set to a matching module, and carrying out the recognition of a current grounding fault. After the processing center receives the characters transmitted by the area module, the processing center enables the historical data block to integrate the historical fault data corresponding to the characters and the feature codes into a fault set according to the characters, enables the historical database to transmit the fault set to the matching module, and the matching module carries out data matching on the data set and the fault set. Through the system, the feature code of the fault area only needs to be compared with the fault set in the corresponding area in the historical data frame and does not need to be compared with all the fault sets in the historical data frame, the data comparison process is simplified, the fault data comparison efficiency is improved, and the fault point of line segment current grounding can be quickly positioned.

The invention relates to the technical field of medical instruments, in particular to a head fixing device which comprises a bed body, a mounting seat arranged in a bed head mounting shell of the bed body and a forehead clamping mechanism arranged on the rear side of the top of the mounting seat and connected with the pillow through a traction piece, a clutch mechanism is arranged on the rear side of the forehead clamping mechanism and connected with the forehead clamping mechanism through three telescopic electromagnetic rods. The cheek clamping mechanisms are arranged on the left side and the right side of the pillow and connected with the clutch mechanism, and the problems that in the prior art, a head fixing device for traditional Chinese medicine is prone to being pressed too tightly or loosened in the actual use process, the head fixing adaptability and precision are insufficient, linkage is lacked, and the clinical operation efficiency is low are solved. The problems that in the prior art, vomiting complications of a patient after lumbar puncture are not considered, body position changes of the patient are easily caused, the illness state is aggravated, the convenient reset unlocking capacity is not achieved, and secondary injury is easily caused when fixation is removed are solved.

This invention belongs to the field of medicinal chemistry technology, specifically relating to Icetexane-type abiane diterpenoid derivatives, their preparation methods, and applications. The Icetexane-type abiane diterpenoid derivatives have the structure shown in formula (I), exhibiting a novel structure and good therapeutic and / or preventive effects against acute lung injury.

The present application belongs to the field of pharmaceutical chemistry, and particularly relates to a triazine compound shown in formula (I) and a preparation method and use thereof.

This invention discloses the application of lupinone in the preparation of drugs for treating psoriasis, belonging to the field of pharmaceutical technology. In this invention, lupinone is used to treat psoriasis by regulating CD4 levels in psoriasis patients. + FoxP3 + The number of Tregs, regulatory T lymphocytes, reduces the expression of CD3-positive cells and the level of inflammatory factors in the skin lesions of psoriasis patients, thereby regulating the immune response of psoriasis patients and thus achieving the treatment of psoriasis. Specifically, it can reduce the severity of psoriasis, improve the degree of erythema, scaling and infiltration of skin lesions, significantly reduce the PASI (Psoriasis Area and Severity Index) score of skin lesions, reduce the thickness of the epidermis at the skin lesion site and inhibit epidermal proliferation, improve hyperkeratosis and parakeratosis, and improve acanthosis.

The invention provides a deferrization agent and a preparation method and application thereof.The method comprises the steps that S1, molecular sieve powder, alumina powder, carbon powder, a first surface active agent, silica sol, ammonium phosphate and acid are mixed and kneaded for 30-60 min, then forming and drying are conducted, and a precursor is obtained; s2, carrying out modification treatment on the precursor in a mixed aqueous solution of quaternary ammonium base and a second surfactant for 0.5-2 hours, and roasting the obtained modified precursor to obtain a deferrization agent; and the acid amount of the deferrization agent is further limited. The deferrization agent prepared by the method can effectively remove inorganic iron and organic iron (especially petroleum acid iron) in hydrocarbon raw materials, and high deferrization efficiency is achieved.

A computer system dealing with digestive health (such as diarrhea) can help guide users to content particularly relevant to their experience without requiring traditional user-input search terms. Such a system can receive user-specific time-series data indicating the user's recorded diet, mood, and diarrhea symptoms. This data can be captured in a daily journaling application on a smartphone. The system can use this data to determine the correlation between the user's recorded diet and mood information and the user's recorded diarrhea symptom information. Appropriate content units can then be selected from multiple content units based on the determined correlation, such as from a database of digestive health information. The selected units can then be presented to the user.

An improved method for recovering the protein expressed by open reading frame 2 from porcine circovirus type 2 is provided. Also provided is recombinant PCV2 ORF2 protein, and immunogenic compositions comprising PCV2 ORF2 protein. Moreover, multivalent combination vaccines are provided which include an immunological agent effective for reducing the incidence of or lessening the severity of PCV2 infection, preferably PCV2 ORF2 protein, or an immunogenic composition comprising PCV2 ORF2 protein, and at least one immunogenic active component of another disease-causing organism in swine,

This utility model relates to the field of truck manufacturing technology and discloses a reinforced side guardrail assembly for trucks, including a mounting plate. A placement frame is provided on one side of the top center of the mounting plate, and fixed plates are fixedly connected to the left and right sides of the top of the placement frame. A sliding plate is provided inside the fixed plate, and a buffer plate is provided on the top of each sliding plate. In this utility model, the sliding plate, fixed plate, limiting hole, first sliding groove, second sliding groove, slider, and adjusting bolt work together to allow adjustment according to trucks of different heights and lengths, making the truck side guardrail fit the truck body more closely and improving installation versatility. The buffer plate, support plate, buffer spring, elastic pad, insert plate, insert block, and L-shaped plate work together to effectively reduce the impact force on the side of the truck, reducing injury to cargo and occupants, and facilitating the convenient repair or replacement of damaged parts, reducing maintenance time and costs.