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1708results about How to "High sensitivity" patented technology

Sensor and method for providing high transfer rate in page-based optical data storage

ActiveUS7446297B1without reducing sensitivityefficiently formedSolid-state devicesMaterial analysis by optical meansOptoelectronicsActive layer
A sensor and method for page-based optical data storage. The sensor includes a partially-reflective mirror, a reflective mirror disposed substantially collinear with and spaced apart from the partially-reflective mirror, and an active layer disposed substantially collinear with and between the partially-reflective mirror and the reflective mirror. The partially-reflective mirror has a first and second side and transmits a portion of light incident on the first side. The reflective mirror reflects light incident on the reflective mirror toward the partially-reflective mirror. The active layer absorbs at least a portion of the light oscillating at the resonant frequency.
Owner:ORACLE AMERICAN INC

Method for diagnosing and / or evaluating retinal disease

InactiveUS20120087864A1increases the effective pharmacokineticsincrease concentrationSenses disorderOrganic active ingredientsDiseaseRetinal function
The present application provides a method for diagnosing and / or evaluating the presence or absence, severity or degree of the improvement of a retinal disease in a subject, which comprises determining and / or evaluating circulatory parameters, retinal function, retina morphology and / or visual relating quality of life (QOL).
Owner:R TECH UENO

Excavator handle control system for remote operation

The embodiment of the invention provides an excavator handle control system for remote operation, a handle control method based on a Hall sensor is adopted, non-contact rocker data sensing is achieved, the influence of contact and movement abrasion on the service life of a handle is reduced, and the excavator handle control system has the advantages of being high in sensitivity and good in performance; the handle mechanism is more flexible to operate, and the service life of the handle is prolonged; a two-hand cooperative control mode is adopted, and two three-degree-of-freedom handles are used for simulating the driving environment of a real excavator, so that a good remote control effect is achieved, and the feeling of presence of an operator in the remote operation process is improved; the operation habits of a driver are fully considered, the walking and working of the excavator are respectively controlled through combination of different degrees of freedom of the left hand handle and the right hand handle, an operating lever of the real excavator is simulated in the aspects of structure, motion degree of freedom and working range, and the man-machine interaction environment of excavator driving is restored.
Owner:GUANGZHOU INST OF ADVANCED TECH CHINESE ACAD OF SCI

Breathing machine inspiration detection method and device and computer readable storage medium

The embodiment of the invention provides a breathing machine inspiration detection method and device and a computer readable storage medium, and the method comprises the steps: collecting first pressure data and first flow data in a current breathing period, and calculating a target flow baseline according to the first pressure data, the first flow data and a preset fitting formula; calculating a virtual traffic baseline according to the target traffic baseline and the first traffic data; if it is judged that the inspiration triggering state is not reached or the virtual inspiration flow change rate in the inspiration triggering state is smaller than a preset flow change threshold value, second pressure data and second flow data of the next respiratory cycle are continuously collected, and the virtual inspiration flow change rate is calculated; and judging that inspiration is detected until the detected virtual inspiration flow change rate is greater than or equal to the preset flow change threshold value. According to the invention, the phenomena of inspiration detection delay, group delay and the like can be avoided, the difference between detected inspiration and actual inspiration is reduced, and the sensitivity of inspiration detection is improved.
Owner:HUNAN BIYANG MEDICAL TECH CO LTD

Multi-process mode intelligent switching method and system for vehicle-mounted sludge treatment

The invention provides a multi-process-mode intelligent switching method and system for vehicle-mounted sludge treatment, and the method comprises the steps: carrying out the time-space alignment and standardization of multi-dimensional sensing data such as sludge characteristics, environmental parameters and equipment states, carrying out the real-time reasoning of a process switching critical value through combining with a lightweight incremental regression model, generating a self-adaptive threshold value band with a confidence interval, and carrying out the real-time reasoning of the process switching critical value. Dynamic monitoring and mode switching pre-judgment of actual operation parameters are realized; in the switching process, a weighted fusion progressive transition control strategy is adopted, the transfer rate is adaptively adjusted according to real-time feedback, the operation stability is guaranteed, and the intelligence, reliability and switching smoothness of process switching of the vehicle-mounted sludge treatment system are remarkably improved.
Owner:GUANGZHOU CHENGYUAN ENVIRONMENTAL PROTECTION EQUIP ENG CO LTD

Electrophotographic photoreceptor, process cartridge, and image forming apparatus

The invention relates to an electrophotographic photoreceptor, a process cartridge, and an image forming apparatus. The electrophotographic photoreceptor includes a conductive substrate and a photosensitive layer of a single-layer type disposed on the conductive substrate. The photosensitive layer has an absorption coefficient of 0.008 or less at a wavelength of 1000 nm and contains a binder resin, a charge generating material, an electron transporting material, and a hole transporting material. The charge generating material is at least one selected from a hydroxygallium phthalocyanine pigment and a chlorogallium phthalocyanine pigment and is contained in an amount of 0.9% by weight or more and 1.8% by weight or less relative to the binder resin.
Owner:FUJIFILM BUSINESS INNOVATION CORP

A primer and probe set, kit, and application for detecting Staphylococcus aureus L based on real-time fluorescence MIRA technology.

ActiveCN121204310BOptimizing real-time fluorescence MIRA detection methodThe detection method is simpleMicrobiological testing/measurementMicroorganism based processesStaphylococcus aureusSingle strand
This invention discloses a primer and probe set, a kit, and their applications for detecting Staphylococcus aureus L based on real-time fluorescence MIRA technology. The primer and probe set consists of single-stranded DNA sequences 1-3. Based on the aforementioned primer and probe set, this invention establishes and optimizes a real-time fluorescence MIRA detection method for Staphylococcus aureus L. Furthermore, the optimized real-time fluorescence MIRA method is innovatively combined with a simplified nucleic acid extraction method and a portable fluorescence detection device, significantly reducing extraction and time costs while enabling rapid on-site detection of the virus, making it particularly suitable for grassroots units and remote areas. In addition, the real-time fluorescence MIRA detection method for Staphylococcus aureus L established in this invention has advantages such as high specificity, high sensitivity, and simple operation. Moreover, the detection process does not require opening the lid, effectively avoiding aerosol contamination, providing an effective technical means for the differential diagnosis and rapid detection of Staphylococcus aureus L.
Owner:FRUIT TREE INST OF CHINESE ACAD OF AGRI SCI

Multi-reflection superposition enhanced microwave displacement measurement method and system

PendingCN121763247AAmplify modulation effectshigh sensitivityUsing optical meansRadio wave reradiation/reflectionMicrowave propagationPhase change
The invention provides a multi-reflection superposition enhanced microwave displacement measurement method and system, and the method comprises the steps: S1, constructing a microwave multi-reflection propagation path, enabling a microwave radar to transmit electromagnetic waves to the microwave multi-reflection propagation path as a transmission signal, and receiving a corresponding echo signal; s2, extracting length change information of a microwave multi-reflection propagation path according to the echo signal; s3, establishing a linear superposition relation model between the total length of the microwave propagation path and respective displacements of W reflection surfaces in the microwave multi-reflection propagation path; w2; and S4, based on the linear superposition relation model, displacement information of the corresponding reflection surface is obtained and output. According to the invention, a larger phase variation can be obtained under the condition of small displacement or weak vibration, so that the measurement sensitivity is improved and the signal-to-noise ratio is improved.
Owner:SHANGHAI JIAOTONG UNIV

Quantum key management method and system for satellite internet biological characteristics

The invention relates to a quantum key management method and system for satellite internet biological characteristics, and the method comprises the following steps: carrying out the registration of biological characteristics and the initialization of communication protocol parameters for a user terminal which is accessed for the first time; for the registered user terminal, before initiating communication each time, binding the real-time biological characteristics with the quantum key, and carrying out encrypted transmission of the session key by using the bound quantum key, so as to carry out encrypted transmission of satellite internet transmission data by using the session key; and in the encryption transmission process of the satellite internet transmission data, according to a preset period, performing satellite link security level adjustment and quantum key dynamic updating. According to the invention, identity authentication and terminal authentication in a high-delay and narrow-bandwidth application scene can be realized, the security problems of identity counterfeiting, key leakage and the like are solved, and the method can be applied to satellite internet scenes such as emergency communication, field operation and the like, and has the advantages of strong compatibility, low deployment cost and the like.
Owner:SPACE STAR TECH CO LTD

Nucleic acid probe, primer group, kit, detection method and application

The invention provides a nucleic acid probe, a primer group, a kit, a detection method and application, and relates to the technical field of biology. The nucleotide sequence of the nucleic acid probe is as shown in SEQ ID NO. 1; wherein the 3'end of the nucleic acid probe is modified with MGB, and locked nucleic acid is modified at a base position corresponding to the difference between the swine fever wild strain and the swine fever vaccine strain in the nucleotide sequence. According to the nucleic acid probe, a specific sequence is utilized to precisely target a swine fever wild strain, and locked nucleic acid modification is introduced at a differential site, so that the recognition capability on single-base mismatch is remarkably enhanced, non-specific binding to a vaccine strain is thoroughly blocked, and false positive interference is eliminated; and 3 '-terminal MGB modification is matched to improve the binding stability and sensitivity, so that the efficient and accurate identification of the swine fever wild strain under the immune background is ensured.
Owner:SANGON BIOTECH (SHANGHAI) CO LTD

Outdoor energy storage power supply data acquisition system based on low-power-consumption edge calculation

PendingCN121978555AImplement dynamic assessmentOvercome the technical defect of being unable to dynamically adapt to load fluctuationsResource allocationElectrical testingElectrical batteryInternal resistance
The invention relates to the technical field of data acquisition, and discloses a low-power-consumption edge calculation outdoor energy storage power supply data acquisition system, which comprises a data analysis unit, a collaborative analysis unit, a probability analysis unit and an acquisition correction unit, and is characterized in that the data analysis unit, the collaborative analysis unit, the probability analysis unit and the acquisition correction unit are combined for analysis; intelligent dynamic regulation and control of outdoor energy storage power supply data acquisition are realized, the defect of data delay under low temperature and high load in a traditional fixed frequency acquisition mode is overcome, the data acquisition effect is ensured, low power consumption is ensured, meanwhile, the real-time recognition capability of hidden dangers such as over-discharge and internal resistance abnormity is improved, and the real-time recognition capability of the hidden dangers such as over-discharge and internal resistance abnormity is improved. And the cycle service life of the battery is effectively prolonged.
Owner:一览众山(厦门)电力技术有限公司

Fluorescence sensor based on DNA molecular machine mediated split Cas12a and application of fluorescence sensor in ofloxacin detection

The invention relates to the field of veterinary drug residue detection, in particular to a fluorescence sensor based on DNA molecular machine mediated split Cas12a and application of the fluorescence sensor to ofloxacin detection, the fluorescence sensor comprises a system A, a system B and a system C. According to the final concentration of each system, the system A comprises an AP / CP double-stranded compound and a 20 mM Tris-HCl buffer solution 1, the system B comprises a double-stranded compound, an sRNA probe and a 10 mM Tris-HCl buffer solution 2, and the system C comprises a DNA molecular machine mediated split Cas12a. The system C comprises a Cas12a / hRNA compound, a pDNA / psG43 signal probe, ThT and a 20 mM Tris-HCl buffer solution; aP in the AP / CP double-chain compound is an aptamer of ofloxacin, and AP and CP in the AP / CP double-chain compound are paired and connected through complementary base pairing; the sequences of AP, CP, PS, SS, sRNA, hRNA, pDNA and psG43 are respectively as shown in SEQ ID NO.1-SEQ ID NO.8. The invention also discloses a kit for detecting the content of the protein. According to the application, the nucleic acid aptamer of ofloxacin is utilized, based on a DNA molecular machine and SCas12a as a signal amplification technology and sulfo-modified G43 as a fluorescent signal probe, even if the content of ofloxacin in a sample is extremely low, detection can be accurately realized.
Owner:LESHAN NORMAL UNIV

A key feature transformer health condition detection system

The application discloses a kind of key feature transformer health state detection systems, it is related to power equipment monitoring technical field, including: data acquisition module, data processing module, confidence calculation module, fault determination module and result output module;Data acquisition module synchronously acquires transformer oil tank surface vibration signal and neutral point direct current data;Data processing module calculates the phase difference of vibration signal and the coherence coefficient of vibration signal and direct current data;Confidence calculation module calculates mechanical fault confidence;Fault determination module judges whether mechanical fault confidence exceeds preset threshold, exceeds and then carries out winding loosening positioning processing, generates loosening coordinate;Otherwise, the multi-band resampling of vibration signal is carried out and the coherence coefficient data is recalculated;Result output module outputs loosening coordinate or interference warning signal;The application can improve the accuracy of transformer health state detection, ensure the reliability of fault positioning.
Owner:SUZHOU TIANDI IND EQUIP INSTALLATION CO LTD

Abrasion online identification and compensation control system and method for high-pressure distribution plunger and barrel assembly

The invention discloses a wear online identification and compensation control system and method for a high-pressure distribution plunger and barrel assembly, and the system comprises a data collection module which is used for collecting working condition data and state data; a health state dynamic baseline model obtained through offline training is arranged in the data processing module, and the wear level of the plunger and barrel assembly is recognized by calculating the residual error between actual state data and health state data predicted by the model under the current working condition; and the compensation control module is used for generating a self-adaptive compensation control instruction according to the identified wear grade and the current working condition and sending the self-adaptive compensation control instruction to an execution mechanism. According to the method, the dynamic base line synchronous with the real-time working condition is constructed, early weak wear characteristics can be separated from strong working condition interference, the recognition sensitivity and accuracy are improved, the influence of wear on the system performance is actively counteracted through closed-loop adaptive compensation control, the service life of equipment is expected to be prolonged, and the system performance is improved. And technical support is provided for predictive wear monitoring management.
Owner:SHAOXING YAKE AUTO PARTS CO LTD

DSP (Digital Signal Processor) online adaptive wavelet denoising and concentration inversion system and method for TDLAS (Tunable Diode Laser Absorption Spectroscopy) measurement

The invention discloses a DSP (Digital Signal Processor) online self-adaptive wavelet denoising and concentration inversion system and method for TDLAS (Tunable Diode Laser Absorption Spectroscopy) measurement, and relates to the technical field of gas spectrum detection. Comprises: a laser module for emitting semiconductor laser light; the absorption cell module is used for absorbing specific components of the laser through a gas absorption cell formed by the to-be-detected gas; the detection and amplification module is used for converting the transmission light signal into an electric signal and amplifying the electric signal through a photoelectric amplifier; the phase-locked amplification module is used for filtering and extracting noise; the digital signal processing module is used for performing digital sampling, performing wavelet denoising and signal reconstruction, performing wavelet inverse transformation reconstruction on a denoised waveform, and extracting a second harmonic characteristic parameter; and the upper computer module is used for obtaining the concentration of the gas to be detected based on a pre-established gas concentration inversion model according to the second harmonic characteristic parameters. The method is suitable for high-precision detection of trace gas, and has the obvious advantages of strong real-time performance, high precision, good system stability, good portability and the like.
Owner:INST OF ENERGY HEFEI COMPREHENSIVE NAT SCI CENT (ANHUI ENERGY LAB)

Aspergillus-targeted sequencing detection primer combination, kit and application

The application discloses a primer combination, a kit and a method for detecting Aspergillus fungi based on targeted sequencing, and belongs to the technical field of microorganism detection. The primer combination comprises a primer pair for detecting common species of Aspergillus, and further comprises a primer pair for detecting at least one cryptic species of Aspergillus, wherein the common species of Aspergillus comprises Aspergillus fumigatus, and the cryptic species of Aspergillus comprises Aspergillus lentulus, Aspergillus udagawa, Aspergillus viridinutans and Aspergillus thermomodestus. The primer combination can be used for detecting Aspergillus fungi based on targeted sequencing, has high specificity and high sensitivity, can effectively distinguish Aspergillus fumigatus from the cryptic species, avoids misjudgment, and thus accurately guides drug use.
Owner:HANGZHOU D A GENETIC ENG

A method for preparing europium ferrite nanosensors and their applications

This invention belongs to the field of gas sensor technology and discloses a method for preparing europium ferrite nanosensors and their applications. This method utilizes electrospinning technology combined with a specific low-temperature confined-domain calcination process (550℃~700℃) to prepare EuFeO3 nanotubes with a hollow structure and rough surface by taking advantage of the thermal decomposition kinetics differences of poly(p-v) magnets (PVP). This process effectively suppresses excessive repair of lattice oxygen while forming a unique tubular morphology, effectively "freezing" oxygen vacancies (O2) accounting for up to 34.44% on the material surface in situ. v This invention addresses the shortcomings of traditional solid fiber materials by constructing a sensor using a grinding, dispersion, and coating process. Utilizing the dual reactive surfaces of hollow nanotubes and high-concentration oxygen vacancy active sites, it achieves highly sensitive and selective detection of low-concentration ethylene gas released during fruit ripening. This invention solves the problems of small specific surface area and insufficient active sites in traditional solid fiber materials.
Owner:TIANSHUI NORMAL UNIV

Broadband wide piezoresistive sensing structure simulating scorpion threshold response characteristic

ActiveCN224151852Ueasy to identifyOvercome the problem of insensitivity to small signal responseForce measurement using piezo-resistive materialsSignal responseMechanical engineering
The utility model relates to the technical field of bionic pressure sensors, in particular to a broadband wide piezoresistive sensing structure simulating scorpion threshold response characteristics, which comprises a threshold adjusting structure and a piezoresistive sensing unit. The threshold value adjusting structure comprises a flexible deformation cover and a threshold value sensing structure base, the flexible deformation cover covers the top end of the threshold value sensing structure base, the piezoresistive sensing unit is arranged in the threshold value sensing structure base, and a rectangular through groove is formed in the bottom of the threshold value sensing structure base; a threading hole is formed in the side wall of the threshold sensing structure base; the flexible deformation cover comprises a sheet, and the center of the lower surface of the sheet is integrally connected with an inverted-cone-shaped protruding block. The problems that the inherent contradiction exists between the sensitivity and the bandwidth performance of an existing piezoresistive sensor, in particular, structural instability under large signals is easily caused when the sensitivity is improved through a traditional design, and the response capacity to small signals is greatly reduced by increasing rigid support to expand the measuring range are solved.
Owner:JILIN UNIVERSITY +1

A MEMS accelerometer

ActiveCN224480494UIncrease the mass areahigh sensitivityCapacitanceAccelerometer
The utility model relates to a kind of MEMS accelerometer, including substrate and multiple sensitive structures being set on the substrate, multiple the sensitive structure is connected by elastic coupling beam structure each other between, each the sensitive structure includes mass and the sensitive capacitor being set on the mass, the mass of adjacent two the sensitive structure is connected by the elastic coupling beam structure each other.The MEMS accelerometer provided by the utility model solves the problem that the existing MEMS accelerometer improves sensitivity and signal-to-noise ratio and leads to the problem of large spring beam thermal stress.
Owner:WUHAN HENGYONG TECH DEV CO LTD

Mycobacterium tuberculosis detection and activity determination method based on fluorescent T7-CRISPR

The invention belongs to the technical field of biology, and relates to a pathogen detection technology based on a CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) system, in particular to a tubercle bacillus detection and activity determination method based on fluorescent T7-CRISPR. The first purpose is to provide a reagent combination for detecting viable tubercle bacillus, and the reagent combination comprises a) a T7 reverse transcription reaction reagent and b) a CRISPR-Cas13a reaction system; a) the T7 reverse transcription reaction reagent comprises a T7 reverse transcription primer and a T7 reverse transcriptase; and b) the CRISPR-Cas13a reaction system comprises specific crRNA, a fluorescence labeled ssRNA reporter, a reaction buffer solution, a Cas13a protein, RNase-Free H2O and a T7 reverse transcriptase. The invention also provides application of the reagent combination in detection of viable tubercle bacillus. The primer combination disclosed by the invention has the advantages of strong specificity and high sensitivity in detection application, can realize rapid detection and visual detection, and is low in detection cost, simple and convenient to operate and suitable for large-scale clinical application.
Owner:NANJING MEDICAL UNIV

Intelligent analysis system for operation failure of electric energy meter based on sensor monitoring

PendingCN122283583Aachieve recognizabilityRealize intelligent analysisPower factorControl engineering
This invention relates to the field of electricity meter operation monitoring technology, specifically to an intelligent analysis system for electricity meter operation faults based on sensor monitoring. The system includes: an operation status acquisition module, which collects the voltage, current, active power, reactive power, and power factor of the electricity meter and obtains the operation status at each moment; a periodic analysis module, which uses active power as a load parameter and obtains a basic period based on the load parameters within a preset time period, then segments the preset time period to obtain different time periods and obtains the period fit at each moment; and a fault monitoring module, which obtains the comprehensive rationality of the load linkage deviation at each moment; and uses the comprehensive rationality of the load linkage deviation at a moment and the period fit to correct the squared Mahalanobis distance corresponding to the data points composed of voltage, current, reactive power, and power factor at that moment, and uses the corrected squared Mahalanobis distance for fault monitoring. This application can effectively monitor the operation faults of electricity meters.
Owner:XIAN LIANGLI INSTR & METER

Airway structure and electronic nebulizer

ActiveCN224291283Uhigh sensitivityincrease negative pressureTobaccoNebulizerMedicine
The application discloses an air passage structure and an electronic atomizer. The air passage structure comprises a plate body, a communication hole, a communication channel, a first air outlet and a second air outlet. The plate body comprises a first plate surface and a second plate surface facing away from each other. The communication hole, the first air outlet and the second air outlet are respectively arranged in the plate body and penetrate through the first plate surface and the second plate surface. The communication hole is used for communicating with the outside atmosphere. The communication channel is formed in the first plate surface and / or the second plate surface. The first air outlet is used for communicating with a suction nozzle of the atomizer. The communication hole, the communication channel and the first air outlet are sequentially connected to form a first air passage capable of connecting and awakening a sensing component of the atomizer. The second air outlet is used for communicating with a mist suction channel of the atomizer and the outside atmosphere. The second air outlet is connected to the first air outlet. The air passage structure can improve the sensitivity of awakening the sensing component to start.
Owner:SHENZHEN SKE TECH CO LTD

A method for preparing a coating using a homogeneous dispersion

PendingCN122524514Aavoid wastingreduce risk
The application provides a method for preparing paint by homogenization dispersion, probe system construction is realized by specific molecular docking and ultrasonic cavitation, hydration kinetics characteristics are extracted by using a fiber array and time-resolved analysis, shear and low-frequency pulse shear processes are intelligently triggered, and interface particle ordered assembly and directional arrangement of fluorinated polymer side chains are induced by a non-steady shear field; finally, through micro-vibration assisted annealing and phase domain optimization, a dispersion with uniform particle size distribution, stable potential and double continuous nano-phase separation characteristics is obtained, and the application realizes synergistic regulation of microstructure and macroscopic performance, and significantly improves film forming compactness and storage stability of the paint dispersion.
Owner:GUANGZHOU FUSIDA CHEM PROD CO LTD

An endoscope abnormal bending detection method, system, terminal and storage medium

The application belongs to the technical field of medical robots, and discloses an endoscope abnormal bending detection method, system, terminal and storage medium, which comprises the following steps: acquiring relative motion data between an endoscope distal end and an instrument box; acquiring an endoscope image sequence, and analyzing an endoscope motion state according to the endoscope image sequence; acquiring push force change data detected by a force sensor; and performing fusion analysis according to the relative motion data, the endoscope motion state and the push force change data to obtain an endoscope abnormal bending detection result. The application combines multi-modal information of displacement, vision and push force sensors, and accurately identifies the abnormal bending condition of the endoscope through real-time data monitoring and analysis.
Owner:SHENZHEN INST OF ARTIFICIAL INTELLIGENCE & ROBOTICS FOR SOC +1

A method for detecting meloxicam and its isomers by high performance liquid chromatography

The present application relates to a kind of methods for detecting meloxicam and its isomers by high performance liquid chromatography, which uses high performance liquid chromatography for detection, and the chromatographic column uses covalent bond and cellulose-tris (3, 5-dichlorophenyl carbamate) as filler;With n-hexane-ethanol-trifluoroacetic acid-triethylamine as mobile phase;Isocratic elution;Column temperature is 20~30 ℃;Flow rate is 0.8~1.1ml / min;Detection wavelength is 215nm.The high performance liquid chromatography detection method of meloxicam and its isomers provided by the present application can realize the complete separation of meloxicam main component and its three isomer impurities, and this method has strong specificity, high sensitivity and good durability, and can be used for the quality control of meloxicam bulk drug.
Owner:NCPC NEW DRUG RES & DEV

Rapid analysis method of polyethylene glycol additive in copper electrodeposition solution

PendingCN122361331Ashort analysis timecaused by interferencePhosphomolybdic acidCopper interconnect
This invention relates to the field of electroplating solution analysis technology, and in particular to a rapid analytical method for polyethylene glycol (PEG) additives in copper electrodeposition solutions. The method involves protonated PEG forming a macromolecular complex colloid with phosphomolybdate under acidic conditions of pH 1.0–2.0. This colloid exhibits maximum absorption at 372 nm, and the absorbance value is directly proportional to the PEG concentration in the formed complex colloid. This allows for quantitative analysis of PEG in the copper electrodeposition solution. Because the phosphomolybdate-PEG complex colloid selected in this invention has excellent selectivity, and no sample pretreatment is required, this invention offers advantages such as ease of operation, speed, high sensitivity, and good selectivity. It is particularly suitable for intermediate control analysis in production environments, such as for electroplated copper interconnects in chips and printed circuit boards, as well as electrolytic copper foil for negative electrode current collectors and copper-clad laminates in energy storage batteries.
Owner:CHANGZHOU UNIV +1

Anti-chlorpromazine monoclonal antibodies and uses and products thereof

The application provides an anti-chlorpromazine monoclonal antibody and application and product thereof, and relates to the technical field of biology.The anti-chlorpromazine monoclonal antibody provided by the application has a variable region, which comprises a complementarity determining region CDR1-VH with an amino acid sequence as shown in SEQ ID NO.1, a complementarity determining region CDR2-VH with an amino acid sequence as shown in SEQ ID NO.2, a complementarity determining region CDR3-VH with an amino acid sequence as shown in SEQ ID NO.3, a complementarity determining region CDR1-VL with an amino acid sequence as shown in SEQ ID NO.4, a complementarity determining region CDR2-VL with an amino acid sequence as shown in SEQ ID NO.5 and a complementarity determining region CDR3-VL with an amino acid sequence as shown in SEQ ID NO.6.The antibody has good specific binding capacity for chlorpromazine.
Owner:SURE BIOTECH (HANGZHOU) LTD

Method, system, kit and probe for detecting BRCA2 gene mutation

The invention relates to the technical field of molecular detection, in particular to a method, a system, a kit and a probe for detecting BRCA2 gene mutation. The detection method comprises the following steps: carrying out pretreatment and PCR amplification on a blood sample, carrying out a hybridization reaction with a probe to obtain a sample, detecting the sample based on an SERS technology, and collecting an SERS spectrum. Whether BRCA2 gene mutation exists or not is judged by identifying characteristic double peaks of a cy3 fluorophore at 1188 cm <-1 > and 1393 cm <-1 >, and the whole detection process can be completed within 2 hours. According to the scheme, the region, carrying the BRCA2 gene, on the DNA can be amplified through the specific primer pair, then the DNA is specifically combined through the improved oligonucleotide probe, and detection is achieved through the reporter molecule on the oligonucleotide probe; therefore, the detection method provided by the scheme has the advantages of high detection speed, high sensitivity and high detection result accuracy, and the problems of long time consumption and high cost of the traditional PCR or NGS technology are effectively solved.
Owner:THE FIRST AFFILIATED HOSPITAL OF ANHUI MEDICAL UNIV

Sound production unit

ActiveCN224249840Unovel structureIncrease the magnetic field strengthElectrical transducersSound productionMechanical engineering
The utility model discloses a sounding unit, including basin stand, magnetic circuit system, conducting centering disk and a plurality of voice coil, magnetic circuit system is connected basin stand, magnetic circuit system includes yoke, and the central magnetic subassembly and first side magnetic structure that are respectively provided on yoke, central magnetic subassembly is located between at least one group of two oppositely arranged first side magnetic structure, the central magnetic assembly comprises a plurality of central magnetic structures which are arranged side by side, the yoke is provided with a window, two opposite side edges of the window are respectively connected with flanges, and the flanges are provided with openings; the voice coils and the central magnetic structures are arranged in a one-to-one correspondence manner, and partial areas of the voice coils are located between the central magnetic structures and the flanges; the conduction centering disk comprises an inner mounting part, a cantilever part and an outer mounting part which are connected in sequence, a partial area of the cantilever part corresponds to the window and is located between the two flanges, one end of the inner mounting part penetrates through the opening and is fixedly connected with the voice coil, and the outer mounting part is connected with the basin stand. The sound production unit has high performance.
Owner:SHENZHEN SUNWAY ACOUSTICS TECH CO LTD

A GUSB photocrosslinking probe, its preparation method and application

PendingCN122277635ASmall hindranceStable in natureAlkyneDiaziridine
This invention belongs to the field of photocrosslinking probe technology, specifically relating to a GUSB photocrosslinking probe, its preparation method, and its application. The GUSB photocrosslinking probe has the general chemical formula C0. 13 H 18 N2O6-R, wherein R is any one of the oxalic group elements or peptide bonds. The R group covalently connects the glucuronic acid recognition core and the photosensitive unit in the GUSB photocrosslinking probe, and the R group contains no more than 4 atoms, resulting in a small size and low steric hindrance. The GUSB photocrosslinking probe provided by this invention uses glucuronic acid as the recognition core, combined with a small-volume diazacyclopropane photosensitive unit and a terminal alkyne group, to achieve µM-level in-situ covalent capture of active GUSB in complex systems such as cells or tissues. The probe of this invention significantly improves positioning accuracy, sensitivity, data availability, quantification, and enrichment, while also possessing advantages such as modular synthesis, mild conditions, and strong system compatibility, effectively addressing the technical shortcomings of existing technologies that struggle to accurately obtain GUSB activity in situ under low-dose conditions.
Owner:SHENZHEN UNIV