1316results about How to "high sensitivity" patented technology

A system and method for imaging of a sample, e.g., biological sample, are provided. In particular, at least one source electro-magnetic radiation forwarded to the sample and a reference may be generated. A plurality of detectors may be used, at least one of the detectors capable of detecting a signal associated with a combination of at least one first electro-magnetic radiation received from the sample and at least one second electro-magnetic radiation received from the reference. At least one particular detector may have a particular electrical integration time, and can receive at least a portion of the signal for a time duration which has a first portion with a first power level greater than a predetermined threshold and a second portion immediately preceding or following the first portion. The second portion may have a second power level that is less than the predetermined threshold, and extends for a time period which may be, e.g., approximately more than 10% of the particular electrical integration time.

3D accelerometer for measuring three components of inertial force (or acceleration) vector with respect to an orthogonal coordinate system, which has high sensitivity due to a big proof mass located within a cavity beneath the surface of the sensor die. The size of the cavity and the size of the proof mass exceed the corresponding overall dimensions of the elastic element. The sensor structure occupies a very small area at the surface of the die increasing the area for ICs need to be integrated on the same chip.

A micromachined capacitive acoustic transducer including an electrode formed by a perforated plate and another electrode formed by a shallowly corrugated membrane anchored at one or more positions on the substrate which also supports the said perforated plate is described. Also disclosed includes: a fixed perforated plate; a movable shallowly corrugated membrane having holes to form acoustic filter to a certain frequency or a range of frequencies spaced from the perforated plate that is anchored in one or more location but loose at other locations; a support structure in the perforated plate maintaining the minimum separation between the membrane and the perforated plate near the perimeter.

A pattern is formed by applying a resist composition comprising a polymer comprising recurring units having an acid labile group-substituted hydroxyl group, an acid generator, and an organic solvent onto a substrate, prebaking the composition to form a resist film, exposing the resist film to high-energy radiation to define exposed and unexposed regions, baking, and developing the exposed film with an organic solvent developer to form a negative pattern wherein the unexposed region of film is dissolved and the exposed region of film is not dissolved.

The invention discloses a quantum dot multicolor marking method for quantitative detection of various cardiovascular disease markers and a kit of troponin I/creatine kinase isoenzyme/myohemoglobin. The method realizes fluorescent quantitative detection by utilizing excellent fluorescent properties of quantum dots and combining a multicolour marking technology and an immunochromatographic assay on the basis of optimizing each component of a test strip. Compared with the common collaurum immunochromatographic assay, the method has the advantages of good mark stability, low nonspecificity, high sensitivity, wide linear range, small cross interference, and accuracy in quantification. The kit disclosed by the invention is used for carrying out quantification detection on the troponin I, the creatine kinase isoenzyme and the myohemoglobin simultaneously, is suitable for detection of whole blood, blood serum and plasma samples, can provide a reference for cardiovascular and cerebrovascular disease diagnosis, and is widely applied to primary hospitals and clinics.

A method for detecting component concentrations in human gas emissions such as breath and gas emitted from skin. A gas sample containing a specified component is collected into a gas cell using a pump and a series of valves to draw the gas sample into the cell and control the gas pressure within the cell. A tunable optical radiation beam is passed through the gas cell and the amount of energy absorbed by the specified component may be measured indirectly by taking the difference between the incident and emerging beam energy or directly by optoacoustic methods. Concentrations of the specified component as small as 0.1 ppB may be determined. Additionally, the tunable optical radiation beam may be multiplexed for use with a plurality of systems utilizing the beam for medical purposes.

The invention relates to an assay kit for neutrophil gelatinase-associated lipocalin (NGAL), in particular to an assay kit for detecting the concentration of the NGAL in human body fluids and a preparation method for the assay kit. The kit comprises a reagent R1, a reagent R2 and a working calibrator, wherein the reagent R1 is a buffer solution which is suitable for antigen-antibody reaction; and the reagent R2 is a solution simultaneously containing nanospheres which have two particle sizes and are combined with an anti-human NGAL antibody, and ensures that the nanospheres are coagulated to cause the change of the turbidity through antigen-antibody specific reaction, and the NGAL can be quantificationally determined by contrasting calibration curves. The kit has relatively high sensitivity when determining low NGAL concentration and has a relatively wide linear range when determining high NGAL concentration, so a prozone phenomenon is avoided. The kit has stable physical and chemical properties, is convenient to use, and has a broad application prospect in clinical laboratory science.

A compact corrosion measurement apparatus and system includes an air fan, a corrosion sensor, a temperature sensor, a humidity sensor, a heater element, and an air flow sensor all under control to monitor and maintain constant air parameters in an environment and minimize environmental fluctuations around the corrosion sensor to overcome the variation commonly encountered in corrosion rate measurement. The corrosion measurement apparatus includes a structure providing an enclosure within which are located the sensors. Constant air flow and temperature is maintained within the enclosure where the corrosion sensor is located by integrating a variable speed air fan and a heater with the corresponding feedback loop control. Temperature and air flow control loops ensure that corrosivity is measured under similar conditions in different facilities offering a general reference point that allow a one to one comparison between facilities with similar or different pollution levels.

The invention discloses an MXene/rGO complex 3D structure based high-sensitivity sensor. The sensor is characterized that an MXene/rGO complex 3D structure serves as a sensing active part of the sensor; and in the MXene/rGO complex 3D structure, MXene is dispersed in reduced oxidized graphene (rGO). The composition and structure of the sensing active part in a sensor piezoresistive type pressure sensor are improved, the MXene/rGO composite structure (especially MXene/rGO composite aerogel) of the 3D structure is introduced, the MXene nanosheets of smaller sizes are dispersed in the oxidized graphene GO nanosheet colloidal solution, and finally the MXene/rGO complex 3D structure in which MXene is dispersed in reduced oxidized graphene (rGO) is formed; and the sensing sensitivity of the piezoresistive sensor can be improved greatly.

The invention discloses a normal atmosphere chemical ionization source for surface desorption of a velocitron. A capillary and a spray point arranged in the capillary constitute a reagent ion generation system. When the reagent admitted through the capillary is sprayed out from one end of the capillary, the reagent is ionized to generate ions of the reagent due to the corona discharge of a discharge electrode; the reagent ions impact specimens inside a specimen disc to ionize the specimens, and the specimen ions are admitted into the velocitron inlet capillary to be used for detection. The ionization source disclosed by the invention is equipped with a moving interface, which can be connected with common velocitrons, such as LCQ, LTQ, TSQ and so on, so that the ionization source can be upgraded and become more powerful. The invention achieves quick and sensitive measurement of complicated basal body specimens by adopting the surface desorption atmospheric pressure chemical ionization mass-spectrometric technique under the condition that sample pretreatment is not required. In addition, the invention is applicable for real-time on-line non-destructive analysis in situ during industrial or environmental course. The ion source is joined with related velocitrons, and can achieve different detection modes, such as cation detection, anion detection, free radical ion detection and so on, according to the properties of specimens.

Corrosion sensor apparatus are disclosed for detection of contamination affecting metal based components and devices. For example, an apparatus comprises: a set of corrosion sensor elements comprising a first corrosion sensor element and at least a second corrosion element, each corrosion sensor element being coupled between a source and a monitor, wherein a width of the first corrosion sensor element is different than a width of the second corrosion sensor element, wherein each corrosion sensor element is susceptible to corrosion caused by an operating environment of the corrosion sensor elements; and a set of reference elements comprising a first reference sensor element and at least a second reference sensor element, each reference sensor element being coupled between the source and the monitor, wherein a width of the first reference sensor element is substantially equal to the width of the first corrosion sensor element and a width of the second reference sensor element is substantially equal to the width of the second corrosion sensor element, wherein each reference sensor element is not substantially susceptible to corrosion caused by the operating environment of the corrosion sensor elements.

The invention relates to a process for extracting glucose and/or xylose for preparing ethanol by utilizing straw plants which comprises, at room temperature, mixing stalk with diluted acid solution by the weight ratio of 1 : 4.5-8.5, elevating temperature to 90-100 deg. C, keeping constant temperature, quickly dissolving the hemicellulose in the stalk, abstracting glucose solution, preparing ethanol from glucose solution fermentation. The glucose solution can be charged by non-dissolved cellulose in the cellulose hydrolysis glucose solution. The process can increase the sensitivity of fabric in the stalks to cellulose.

A dark-field imaging method for detecting defects in reflective lithography masks (e.g., extreme ultraviolet (EUV) masks) used, e.g., in processes for the fabrication of microelectronic devices. A mask blank is coated with a photoresist layer having a fluorescent dye incorporated therein. The photoresist layer is exposed to a source of radiation (e.g., EUV radiation or glancing soft X-rays). In areas of the mask blank having defects the combined direct and reflected radiation will be insufficient fully to expose the photoresist layer. After development, photoresist will remain on the mask blank surface in areas corresponding to defects. Illumination with the excitation wavelength of the fluorescent dye reveals the location of any remaining photoresist, which can be detected using an optical microscope, thereby to detect defects in the mask blank.

The invention relates to a test strip used for detecting immune colloidal gold remaining in kanamycin. The test strip comprises a sample pad, a combination pad, a cellulose nitrate membrane, a water absorbing pad and a PVC back lining, wherein, the sample pad, the combination pad, the cellulose nitrate membrane and the water absorbing pad are continuously stuck on the PVC back lining in sequence,lapping is arranged between the combination pad and the cellulose nitrate membrane, and lapping is arranged between the cellulose nitrate membrane and the water absorbing pad; an anti-kanamycin monoclonal antibody-colloidal gold label is coated on the combination pad, and a detection line formed by a kanamycin-carrier protein (bovine serum albumin) coupling compound and a quality controlling lineformed by a rabbit anti mouse are coated on the cellulose nitrate membrane. The test strip of the invention has the advantages that the specificity is strong, the sensitivity is high, the detection time is short (10 minutes), the test strip can be operated on site, the detection cost is low, the operation is simple, and the test strip is not required to be operated by professionals.

To provide a hologram recording method capable of satisfying high sensitivity and at the same time, satisfying high diffraction efficiency, good preservability, low shrinkage percentage, dry processing and multiplex recording properties, a hologram recording method comprises a first step of producing a latent image upon holographic exposure, and a second step of causing a polymerization reaction due to the latent image, to form a interference fringe providing a refractive index modulation, wherein the first and second steps are dry process; particularly, the first step is a step of producing a colored material to form the latent image and the second step is a step of causing the polymerization reaction upon irradiating the colored material with a light having a wavelength different from that of the holographic exposure, to form the interference fringe providing the refractive index modulation.

A capacitive sensing array device of an electronic apparatus includes sensing electrodes, a shielding conductor layer, a coupling signal source, a constant voltage source and switch modules. The coupling signal source provides a coupling signal coupled to an object. The constant voltage source provides a constant voltage to the shielding conductor layer to form a stable vertical parasitic capacitor between the shielding conductor layer and each sensing electrode. Each switch module is electrically connected to the constant voltage source via the corresponding sensing electrode. When one sensing electrode is selected to perform sensing, the corresponding switch module is configured as an open-circuited state such that the selected sensing electrode is disconnected from the constant voltage source, while the other sensing electrodes are electrically connected to the constant voltage source to form a stable horizontal parasitic capacitor between the selected sensing electrode and the other sensing electrodes.

A color representation technique to be effectively applicable to a pixel shifted arrangement to realize high sensitivity and high resolution is provided by using a dipersive prism or diffraction.

A dispersive element is provided for an image sensor in which photosensitive cells are arranged to be shifted from each other by a half pitch both horizontally and vertically. The dispersive element makes at least G rays fall straight down to a pixel right under itself and also makes either R rays or B rays incident on an adjacent pixel. Meanwhile, a photosensitive cell, for which no dispersive element is provided, receives directly incident light, too. Color information can be obtained by making computations on photoelectrically converted signals provided by these pixels.

The invention provides a method used for simultaneous detection of three food-borne pathogenic bacteria based on multicolor upconversion fluorescence labeling. According to the method, three upconversion materials with differentiable fluorescence spectrums are used for forming multicolor upconversion fluorescent nanoprobes via respective connection with aptamers of staphylococcus aureus, vibrio parahaemolyticus, and salmonella, and complementary oligonucleotide single chains of the aptamers are connected with magnetic nanoparticles so as to form nano-composites. When bacteria to be tested are in a detection system, double chain unwinding is realized because of specific binding of the pathogenic bacteria with corresponding aptamers; it is possible to realize simultaneous quantitative determination of staphylococcus aureus, vibrio parahaemolyticus, and salmonella by monitoring upconversion fluorescence signal strength at 477nm, 550nm, and 660nm, detection linear range ranges from 50 to 1000000cfu/ml, and detection limits are 25cfu/ml, 10cfu/ml, and 15cfu/ml respectively. The method is used for detection of pathogenic bacteria, is high in sensitivity, is rapid and convenient, and can be used for detection of the three pathogenic bacteria in food such as milk and shrimp meat; and results are accurate and reliable.

The present invention belongs to the alarm technical field for the optical fiber oil and gas pipeline providing an alarm sensing system for distributed optical fiber oil and gas pipeline. The technical proposal of the invention is that: the coherent light emitted from the high coherent length tunable laser enters the input end a of the optical circulator through the sensing optical fiber, outputs to the optical fiber raster reflector entering from the first output end b of the optical circulator and the antiradar reflectivity optical fiber raster reflector, then returns to the optical circulator, outputs to the photodiode by the second output end c of the optical circulator. The signals of the photodiode is magnified by the amplifier and then analyzed the required information by the FFT sideband filter and the spectrum analyzer, finally displayed and prewarned by the computer control system and the prewarning. The invention is mostly used in the alarm sensing system for distributed optical fiber oil and gas pipeline which has simple manufacturing sturcture, accurate position, long monitoring distance, no large monitoring range, high sensitivity and can be set sensitivity in advance.

The present invention provides methods and compositions for the assessment and treatment of asthma and other inflammatory diseases, particularly those mediated by interleukin-13 (IL-13). The present invention also provides arrays comprising markers for asthma as well as IL-13 responsiveness. The markers of the present invention can be used in methods to diagnose a patient as having asthma or an IL-13-mediated condition, to evaluate the effectiveness of potential therapeutic agents, to identify or evaluate agents capable of modulating marker expression levels, and to select a treatment for a patient suffering from asthma or an IL-13-mediated condition.

The invention relates to the field of distance protection research for power transmission line with series compensation capacitor, in particular to a series compensation capacitor power transmission line distance protection method based on model identification. In the method, model identification technology is adopted, a front fault model before the series compensation capacitor is built up, the sampled current and voltage values at the protected site are input into the model for parameters estimation, and at last the error coefficient EF is worked out; the position of the fault point relative to the series compensation capacitor can be determined according to the relationship between the error coefficient and the fixed value, and the fault within the protection range can be detected with the cooperation of an impedance element; in this way the motion of the protection device can be controlled. The method can tell the position of single phase grounding fault point in a series compensation line relative to the series compensation capacitor; combined with the impedance element, the method can eliminate the influence on distance protection from the series compensation capacitor and can improve the sensitivity of the protection device.

An apparatus includes an object and one or more sensors located adjacent to or in the object. The object is formed of a material whose dielectric constant or magnetic permeability has a negative real part at microwave-frequencies. The one or more sensors are located adjacent to or in the object and measure an intensity of an electric or a magnetic field therein.

The invention belongs to the field of medical clinical immediate tests, and relates to a colloidal gold test strip for a double-amplification system and a preparation method thereof. The colloidal gold test strip for the double-amplification system comprises a test strip bottom lining, and a sample pad, a polyester film coated with a gold-labeled antibody, a coating film and absorbent paper whichare lapped with and adhered to the test strip bottom lining in turn, wherein the middle part of the coating film is parallelly provided with a detection line coated with streptavidin and an F(ab)2 fragment of a monoclonal antibody of an antigen to be detected, and a control line coated with a rabbit anti-rat immunoglobulin G (IgG) antibody; the F(ab)2 fragment of the monoclonal antibody of the antigen to be detected and biotin are coated in the sample pad; and the gold-labeled antibody is colloidal gold labeled protein A and the monoclonal antibody of the antigen to be detected. The test strip has the advantages of high specificity, sensitivity and detection speed, has low cost, is easy to operate, can be widely applied to the detection of the antigen to be detected, and lays a foundationfor the timely discovery and prediction and effective detection of diseases, and an instrument and equipment are not required to be used.

The present invention discloses a method and device for transmission of light pilot tone signals. The method comprises: sending test signals of light pilot tone signals to be transmitted to a receiving terminal; receiving feedback channel quality parameters after the receiving terminal processes the test signals, wherein the channel quality parameters are quality parameters of a transmission link from a sending terminal to the receiving terminal; according to the channel quality parameters fed back by the receiving terminal, regulating the modulation coefficient of the light pilot tone signals; and sending the light pilot tone signals modulated through the modulated modulation coefficient. The method and device for transmission of light pilot tone signals have a channel quality parameter detection feedback mechanism, the sending terminal regulates the modulation coefficient of the light pilot tone signals to be transmitted according to the channel quality parameters fed back through the receiving terminal to select optimal modulation coefficient so as to ensure the reliability of each signal in the light pilot tone signals and improve the sensitivity of the light pilot tone signals.

A method and apparatus for automatically controlling the movement of a door over a floor from an open position to a closed position with respect to a door frame, by mounting ultrasonic transmitters at one side of the door frame and oriented to transmit ultrasonic energy downwardly towards the floor and to reflect the energy from the floor upwardly upwardly at the other side of the door frame; mounting ultrasonic receivers over the door frame at the opposite side and oriented to receive the energy from the ultrasonic transmitter reflected by the floor; and processing the reflected energy received by the ultrasonic receiver to detect the presence of an object in the path of the door, when moving toward its closed position, and to automatically interrupt the closing of the door.

There is provided a compact, high-sensitivity acceleration sensor. The acceleration sensor includes a weight 8, a pedestal 9 arranged around the periphery of the weight 8, a support frame 3 formed to have a width narrower than the width of the pedestal 9 all around its perimeter, a mass 2 attached to the weight 8 to retain the weight 8 inside the support frame 3, beams 4 connecting the support frame 3 and the mass 2 and overlapping the pedestal 9 near their ends on the side of the support frame 3, and a peripheral interlayer 12 arranged between the support frame 3 and the pedestal 9 to create a predetermined clearance between the pedestal 9 and the parts of the beams 4 that overlap the pedestal 9.

The invention belongs to the technical field of biology and discloses a group of circRNA markers for early diagnosis of lung adenocarcinoma and application thereof. The circRNA marker disclosed by the invention comprises four kinds of circRNA, namely circRNA-100323, circRNA-69774, circRNA-403738 and circRNA-404449. The invention has the beneficial effects that a group of novel molecular bio-markers with diagnostic values on lung adenocarcinoma are provided. According to verifications of clinical sample cases, the group of circRNA markers have high diagnostic specificity and sensitivity on early diagnosis of lung adenocarcinoma.

The invention discloses a power distribution network failure data self-synchronizing method based on instantaneous amplitude change. According to the power distribution network failure data self-synchronizing method, the instantaneous amplitude of the failure current is calculated by use of the instantaneous sampled values of three-phase currents at the same moment, failure synchronization is realized according to the characteristic that the instantaneous amplitude of the currents after a failure changes suddenly, and whether the failure exists is determined according to whether the magnitude of the sudden change of two cycle current instantaneous amplitudes before and after the failure exceeds a certain threshold; the power distribution network failure data self-synchronizing method has the characteristics of high sensitivity and high speed, and is capable of effectively overcoming the defects of an existing fault detection method, such as slow start, high failure moment detection error and poor self-synchronizing effect in case of failures occurring near a current zero-crossing point; without increasing the construction cost, the clock synchronization accuracy is improved to meet the requirements of the line longitudinal differential protection of the power distribution network.

The invention discloses a preparation method and application of a sinonovacula constricta enzymolysis polypeptide. The method is characterized by comprising the following steps: shelling sinonovacula constricta, washing, mincing, adding water in the material-liquid mass ratio of 1:(3-5) for homogenizing, and adjusting the pH value to 5.5-6.5; adding protease for performing enzymolysis at the temperature of 60-70 DEG C for 1.5-2.5 hours, wherein the adding amount of the protease is 0.2-0.3 percent based on the total mass of sinonovacula constricta; after enzymolysis, performing enzyme deactivation, and centrifuging to obtain supernatant serving as enzymatic hydrolysate; performing ultrafiltration, G-25 gel chromatography and reversed phase high-performance liquid chromatography elution on the enzymatic hydrolysate to obtain the needed sinonovacula constricta enzymolysis polypeptide. A preparation process is simple, the obtained sinonovacula constricta enzymolysis polypeptide is high in sensitivity and stability and small in side effects, plays a remarkable role in inhibiting the proliferation of DU-145 and PC-3 cells through MTT detection, and can be applied to in-vitro resistance of prostatic cancer. The preparation method plays an important role in further researching and developing functional foods and medicaments based on the sinonovacula constricta enzymolysis polypeptide and increasing the economical value of the sinonovacula constricta.

The invention relates to a design and preparation method for a flexible force sensing element based on a continuous three-dimensional graphene or carbon nanotube field effect structure. Field effect conductivity changes under constant grid voltage of graphene or carbon nanotubes covering the surface of an elastomer pyramid strip are used by the sensing element, a grid electrode is design to be a plane flexible electrode covering the graphene or the carbon nanotube pyramid strip or the top end of an array, the area of a source leakage channel is increased under the compressive deformation for a pyramid by the grid electrode, the field effect conductivity is increased, and the element is high in deformation or loading flexibility. By the designation of the width of the strip, the density of the array and the elasticity modulus of base elastomer materials, force sensing elements with different flexibilities in the loading measurement range of 0-3 MPa can be obtained, and a force sensing film of which the transparency is higher than 80% and the bending curvature is less than 3 mm can be designed and prepared.