28results about How to "Wide application" patented technology

The invention discloses a super-hydrophobic surface anti-scouring testing device and a testing method, relates to the technical field of super-hydrophobic treatment, and solves the problem of lack of a super-hydrophobic coating anti-scouring performance testing device suitable for a laboratory. A water tank communicates with an air compressor and a water pump; an objective table is arranged at the bottom in the water tank, a linear nozzle is arranged at the top in the water tank, and the objective table is opposite to the linear nozzle; a ducted fan is arranged on the linear nozzle, and the ducted fan is used for blowing the test sample; a motor is arranged on the side wall of the water tank, and a lead screw is arranged at the output end of the motor and provided with a drainage block. The water pump communicates with the bottom of the water tank through a water inlet pipe and communicates with the linear nozzle through a water outlet pipe. According to the method, environmental variables are controlled, so that the test of the super-hydrophobic reagent is standardized and easy to operate; the device can provide super-hydrophobic reagent test conditions of an underwater scene to meet super-hydrophobic reagent development and test requirements of underwater navigation bodies, ships and other underwater equipment in actual research.

The utility model discloses a screening device for Tpe plastic particles, which relates to the technical field of plastic particle processing equipment, and comprises a screening box, a feed hopper is arranged above the screening box, the feed hopper is fixedly connected with a feed pipeline below the feed hopper, a vibration motor is fixedly arranged at the bottom of the screening box, and the vibration motor is fixedly connected with the feed hopper. A plurality of screening nets with different hole diameters are movably inserted into the screening box, a second discharging opening is formed in the position, above the screening nets, of one side of the screening box, and a first discharging opening is formed in the position, below the screening nets, of one side of the screening box. A stirring structure is arranged at the feeding position of the device, and caked Tpe plastic particles can be dispersed, so that the screening efficiency is improved; the screening net of the device is arranged to be a drawable screening net, and when Tpe plastic particles of different shapes and sizes are screened, different screening nets can be replaced, so that wider application conditions are achieved.

The invention provides a backscatter communication method and related equipment, and relates to the technical field of wireless communication. The method comprises the following steps: receiving the total amount of service data to be transmitted and an environment energy storage value sent by a backscattering terminal; determining a required energy value according to the total amount of the to-be-transmitted service data; under the condition that the required energy value is smaller than the environment energy storage value, the working mode of backscatter communication is determined to be a first communication mode, working mode information is sent to the backscatter terminal so that the backscatter terminal can conduct backscatter communication according to the first communication mode, and the working mode information comprises the first communication mode and the second communication mode. The first communication mode is to transmit all to-be-transmitted service data at one time through the stored environment energy. According to the invention, the energy loss of the backscattering terminal is saved, and the energy loss of the network equipment is also saved.

The present application relates to a preparation method for an antibody-drug conjugate and an application, and in particular, to a compound, or a tautomer, mesomer, racemate, enantiomer, and diastereomer, or mixture thereof, or a pharmaceutically acceptable salt, prodrug or solvate thereof, a preparation method for the compound and related antibody-drug conjugates, and a use of the same in the preparation of drugs for the treating cancer.

The present application relates to the technical field of electrophoretic particles, more particularly to an electrophoretic particle, a preparation method therefor, and an application thereof. Provided is an electrophoretic particle. The electrophoretic particle includes a shell layer and a core layer, which is wrapped in the shell layer. The core layer includes a plurality of core particles, and the density of the core particles is lower than a density of the shell layer. The electrophoretic particle includes the shell layer and the core layer wrapped in the shell layer, the core layer includes the plurality of core particles, and the structure of the plurality of the core particles makes the shell layer wrapping on surfaces of the plurality of the core particles form a folded structure, thus increasing a surface area of the core layer and improving the bonding tightness between the shell layer and the core layer, and making the shell layer of the resulting electrophoretic particle have relatively strong tightness. Based on this, an overall particle size of each electrophoretic particle can be appropriately reduced, the moving velocity of the electrophoretic particle under the action of the electric field can be improved, and it is ensured such electrophoretic particle will never have the light leakage problem, thereby improving the excellent performance of a device.

The utility model relates to the technical field of wire harness conduction equipment, in particular to a movable support for wire harness conduction equipment, which comprises a bottom frame A and a bottom frame B. An outer rod A is welded at the top of the bottom frame A. An inner rod A is slidably connected to the inner side of the outer rod A. A fixing frame A is fixed at one end, far away from the outer rod A, of the inner rod A through a screw. A supporting rod for supporting the conduction plate is welded to the top of the fixing frame A, an outer rod B is welded to the top of the bottom frame B, an inner rod B is slidably connected to the inner side of the outer rod B, and a fixing frame B is connected to the top of the inner rod B through a screw; through the arrangement of the supporting rod, the fixing plate, the bottom frame A, the bottom frame B, the fixing frame A, the fixing frame B and the fixing assembly, the problems that when an existing movable support used for the wire harness conduction equipment is used, a conduction plate and a conduction machine in the wire harness conduction equipment cannot be used separately, and the wire harness conduction equipment is inconvenient to move are solved.

The present application relates to a preparation method for and an application of an antibody conjugated drug, in particular to a compound, or a tautomer, mesomer, racemate, enantiomer, diastereomer, or mixture thereof, or a pharmaceutically acceptable salt, prodrug, or solvate thereof, preparation methods of the compound and related antibody conjugated drug, and uses thereof in the preparation of drugs for treating cancers.

The utility model discloses a newly-added wall bushing structure for an external wall of a basement of an existing building, which comprises an external wall main body, a wall bushing and a plurality of wall bushings, wherein the external wall main body is horizontally provided with a through-wall hole in a penetrating manner; the steel sleeve transversely penetrates through the wall penetrating hole; the water stop steel plate is welded and fixed to the outer wall of the steel sleeve and used for being attached to the outer surface of the outer wall body; the external protection wall is arranged on the outer surface of the outer wall body in a pouring mode and wraps the water stop steel plate. The utility model has the following advantages and effects: by arranging the device integrating reinforcing and water stopping, the whole outdoor space is used as a working surface for concrete pouring, the pouring is more convenient, the construction efficiency is high, the construction difficulty of concrete pouring is effectively reduced, and meanwhile, the integrated device of the steel sleeve and the water stopping steel plate plays a role in reinforcing on one hand, and also plays a role in water stopping on the other hand; and on the other hand, the water stopping effect is achieved.

The present invention relates to an adjuvant ensemble in which two or more immunostimulatory substances for inducing the activation of various immune cells are combined, and to a novel concept of a kinetically acting adjuvant ensemble and use thereof, the treatment order and the time interval are adjusted to maximize the finally exhibited synergistic immunostimulatory response. The kinetically acting is characterized in that the second immunostimulatory substance responds to intrinsic factors (enzymes, redox potential, GSH, and pH) and extrinsic factors (redox, pH, temperature, photo / light, magnetism, ultrasound, and electrical response) in immune cells, and thus chemical binding at a binding site is cleaved, and the active site is exposed so that function is kinetically recovered, or two or more immunostimulatory substances are sequentially released from a carrier at regular time intervals, thus inducing immune activity. In such a novel immunostimulatory adjuvant ensemble, a first immunostimulatory substance and a second immunostimulatory substance can be selected in a personalized manner according to applications, and the adjuvant ensemble can be used for anticancer effects and the development of drugs for the prevention and treatment of infectious diseases.

The invention discloses a fully automatic toilet cleaning device, which relates to the technical field of high-pressure water jet cleaning. The fully automatic toilet cleaning device comprises a box body and a cleaning trolley. A water inlet is provided on the side of the box body. A water storage tank, a pressure pump and a solenoid valve are provided in the box body. The pressure pump is connected to the water storage tank through a pressure pump water inlet pipe, the solenoid valve is connected to the pressure pump through a solenoid valve water inlet pipe, and the cleaning trolley is connected to the solenoid valve through a solenoid valve water outlet pipe; the box body is also provided with an electrically connected gas-sensitive infrared sensing device and a controller. A crawler transmission device, a screw transmission device and a rotating nozzle device are provided in the cleaning trolley. There are two crawler transmission devices, which are respectively arranged on both sides of the screw transmission device, and the rotating nozzle device is arranged on the middle part of the screw transmission device. The cleaning effect of the present invention is good and the cleaning efficiency is high. It not only eliminates the accumulation of dirt in the toilet, but also increases the service life of the toilet.

There has been required a novel and practicable multilayer structure that has enhanced structure stability and, therefore, is improved in the enlargement of device size, easiness in processing, etc. A structure according to the present invention that comprises a core layer comprising a pharmacological ingredient embedded in a chemically crosslinked alginic acid, a cationic polymer layer coating the core layer, and an anionic polymer layer coating the cationic polymer layer.

The invention provides a dynamic multi-port knock network service access method and system, and the method comprises the steps: uploading a knock data package according to a preset knock rule when a user accesses a knock network port; performing first verification on the knock data packet, and if the first verification is passed, calculating a knock authentication port according to a preset authentication port algorithm; the user calculates a knock authentication port according to a preset authentication port algorithm and tries to access the knock authentication port, and if the access is successful, a knock authentication data packet is sent to the port according to a preset knock authentication rule; performing second verification and information authentication on the knocking authentication data packet, and if the second verification and the information authentication are passed, calculating a network service port according to a preset network service mapping port algorithm; and the user calculates the port number and tries to access the network service port of the system, and if the access is successful, the user accesses the network service according to the port number. According to the invention, the security of the service can be improved, and targeted network traffic attacks can be avoided.

The present invention belongs to the field of virology, in particular to the field of hepatitis B virus treatment. Provided are a model and a method for screening HBV cccDNA inhibitors. According to the screening model and the method, the detection of a split luciferase is used as an alternative index of HBV cccDNA detection, and a cccDNA-targeted drug can be screened in high throughput.

An ion screening method and system for a mass spectrometer. The mass spectrometer is provided with a deflection conductor. The screening method comprises: before a laser synchronization pulse signal is output, connecting a first voltage signal to a deflection conductor to generate a deflection electric field for deflecting the flight direction of non-target ions; when the target ions fly out of an accelerating electric field, connecting a second voltage signal to the deflection conductor, such that target ions reach a detector; and when the target ions all pass through the deflection conductor, connecting the first voltage signal to the deflection conductor. According to the present application, the service life of the detector is prolonged, and interference of the non-target ions is avoided. A high-voltage pulse circuit and an ion selection circuit, comprising a circuit consisting of a first voltage source, a second voltage source, a pulse circuit, and an RC series circuit. A difference between voltages output by the first voltage source and the second voltage source is not less than a preset voltage difference; and a transistor switch is turned on and turned off to implement high-low level switching. According to the present application, a buffer duration of high-low level switching in a high-voltage pulse signal is shortened.

A high temperature resistant mannanase mutant, comprising at least one mutation site among D49C / I / N, G58D / E / S, H90L, T99Y, K120Y, N124P, T130D / N / P / Q / R / S, Y132F, S136M, S140L / K, T148K, F206Y, A212N / S / P, L257F, S263R, D268A / E / G / P, G273P, S302M / E, S306M / Q, T315P, T353L / F, D360E / N / K, and A362R. The high temperature resistant mannanase mutant has heat resistance significantly higher than the wild type mannanase, and can be widely used in the field of feeds.

The present application relates to the technical field of new materials, and more specifically, it relates to a preparation method of collagen fiber, a collagen fiber, and an application of collagen fiber, including the following steps: (1) spinning solution: soak the collagen material in a solution with a pH of 3.5 to 5.5 and dissolve it, then adjust the pH to 9.9 to 12.5 to form a spinning solution ; (2) as-spun fiber: the spinning solution enters the coagulation bath with a pH of 4.4 to 6.8 for coagulation and spinning to form as-spun fiber.

An application of iron oxide nanoparticles (IONPs) in the preparation of a parathyroid and / or lymph node contrast agent, wherein the particle size of the IONPs is 1-1000 nm, the polydispersity index is <0.3, the zeta-potential is -50 to 50 mV, and the peak value of an ultraviolet-visible absorption spectrum is 100-500 nm. The IONPs may accurately negatively visualize parathyroid glands and trace lymph nodes.

The utility model provides an improved photovoltaic clamp, including first clamping piece, second clamping piece, bolt assembly, first clamping piece includes the first upper roof of C-shaped structure integrated moulding, first support plate, first clamping plate, second clamping piece includes the second upper roof of C-shaped structure integrated moulding, second support plate, second clamping plate, first clamping piece and second clamping piece form the clamping cavity and have second upper roof and top in first upper roof bottom surface after assembling, bolt assembly includes polygonal bolt, second upper roof bottom surface is opposite and is provided with the first hook portion and second hook portion of the restriction polygonal bolt and turn, first hook portion includes first vertical limiting section and first hook, and first vertical limiting section and first hook form first and top step between, second hook portion includes second vertical limiting section and second hook, and second vertical limiting section and second hook form second and top step between. Improved photovoltaic clamp has the advantages of simple structure, convenient installation, low cost, strong applicability.

The present disclosure relates to an anti-CD300c monoclonal antibody and its use for preventing or treating cancer. The anti-CD300c monoclonal antibody according to the present disclosure binds to a CD300c antigen with high specificity and also promotes anticancer immune responses. Thus, this anti-CD300c monoclonal antibody is expected to be effectively used against growth, development, metastasis, and the like of various cancers.

A method of manufacturing a super-junction power device having adjustable resistors connected in parallel between a gate and a source; and the super-junction power device obtained by performing the method are provided. The method includes: preparing a cell structure and the adjustable resistors connected in parallel between the gate and the source of the super-junction power device; preparing contact holes; preparing metal wires; and preparing a passivation layer.

According to the present invention, a rocker arm mechanism of an engine, a system and a method for two-stroke engine brake, the rocker arm mechanism includes a first rocker arm, a second rocker arm and a connection mechanism, wherein one end of the first rocker arm and one end of the second rocker arm is rotatably connected to a shaft, the other end of the first rocker arm is close to a valve of the engine, the other end of the second rocker arm is close to a cam, the connection mechanism includes a connecting piston and a linkage mechanism, the connecting piston is disposed in the first rocker arm or the second rocker arm, the linkage mechanism is rotatably connected to one end of the connecting piston, extension and contraction of the linkage mechanism change length of the connection mechanism between the first rocker arm and the second rocker arm, and motion of the cam transferred to the engine valve(s) is changed. The rocker arm mechanism of the present invention may be used for engine cylinder deactivation and engine brake.

Disclosed are a hybrid dialkylphosphinate salt, a method for preparing same, and use thereof. The hybrid dialkylphosphinate salt is selected from at least one of the compounds represented by Formula (I). The hybrid dialkylphosphinate salt of Formula (I) provided herein features a low required loading level, high flame retardant efficiency for various polymers, and good thermal stability. The present invention overcomes the disadvantage of low flame retardant efficiency of diethylphosphinate in polymers as well as low thermal stability and large dust of dipropylphosphinate. The hybrid dialkylphosphinate salt of Formula (I) can be widely applied to flame retardant polymers which require high-temperature processing.

The present application relates to a method for preparing an antibody drug conjugate and an application thereof. Specifically, the present application relates to a compound, or a tautomer, mesomer, racemate, enantiomer, and diastereomer thereof, or a mixture thereof, or a pharmaceutically acceptable salt, prodrug or solvate thereof, as well as a method for preparing the compound and related antibody drug conjugates and use thereof in the preparation of drugs for the treatment of cancers.

The present invention provides a microparticle comprising 3-hydroxybutanoic acid (3-HB) as a repeating unit of polyhydroxyalkanoic acid (PHA), a biodegradable polymer, and having a particle size of 0.2 um to less than 10 um, and a method for producing the microparticle. The microparticle of the present invention can be used in a wide range of applications, including pharmaceutical applications, because of its biodegradability, excellent processability, and biocompatibility.

This invention provides a pressure balance measurement system for knee replacement surgery, including a pressure signal processing device and a force measuring handle connected via a communication cable. The force measuring handle includes a pressure sensor, a housing, and a support structure. The support structure is connected to the housing via a telescopic tube, which has a bifurcated structure. The main rod of the bifurcated structure is connected to the support structure, and the two branches of the bifurcated structure are each connected to a housing. The distance and angle between the two housings and the support structure are adjustable via the telescopic tube. This invention meets the minimum thickness required for clinical use, has a high pressure measurement range and accuracy, high assessment reliability, an efficient and simple structure, provides bilateral pressure measurement, and the measurement points are adjustable, increasing its versatility in clinical application.

The present invention provides a method for improving ultra-violet light transmittance of ethylene glycol, which includes the following steps: (1) subjecting ethylene glycol, a catalyst and water to a hydrolysis reaction at 120°C-150°C; and (2) adding a stabilizer into a product of the hydrolysis reaction, then conducting distillation at reduced pressure, and condensing to recover a fraction. The method of the present invention can effectively decompose impurities of carboxyl-, conjugated double bond-, aldehydeand ketone-containing complex organic compounds in the ethylene glycol which affect the ultra-violet light transmittance, obviously improve UV values of the ethylene glycol at 220 nm, 275 nm and 350 nm, give consideration to the requirements of environmental protection and safety and economic benefits, and have a broad application prospect.

The present invention relates to a partial discharge monitoring device for a switch cabinet, which comprises: a chassis assembly, which is a cross-shaped box body and has two pairs of traveling wheels symmetrically arranged along the central axis; an obstacle crossing component, which comprises a support plate horizontally attached along the front end surface of the chassis assembly, the front ends of the cantilevers on both sides of the front surface of the support plate are symmetrically provided with mounting holes along the central axis, a transmission shaft is rotatably connected between the two mounting holes, and the ends of the transmission shaft are axially symmetrically provided with foldable and unfoldable obstacle crossing mechanisms, an extension plate is convexly provided on the middle part of the front surface of the support plate, and the transmission shaft is transmission-connected to the driving mechanism arranged on the extension plate; a monitoring mechanism, which comprises a machine arm erected on the top of the chassis assembly, and a partial discharge monitor is detachably clamped on the end surface of the driving end of the machine arm; two auxiliary crawlers, which are symmetrically arranged along the central axis of the chassis assembly and are used to assist the obstacle crossing mechanism in crossing obstacles when it is unfolded; its structural design is reasonable and applicable to a wide range of road conditions.

The invention provides an ergonomic chair adapted to waist support, which comprises a chair back assembly and a waist rest assembly arranged on the chair back assembly in a lifting manner, the chair back assembly comprises a lifting mounting seat, and the waist rest assembly comprises a lifting motion seat arranged on the lifting mounting seat in a lifting manner; a first elastic piece for providing upward elastic force to the lifting motion seat is arranged between the lifting motion seat and the base; the chair back assembly further comprises a movement assembly and a waist rest part, the waist rest part is movably connected to the lifting movement seat through the movement assembly, a second elastic part is arranged between the movement assembly and the lifting movement seat, and the second elastic part always gives forward elastic force to the movement assembly and the waist rest part; the waist rest part responds to external force and ascends and descends and / or moves back and forth relative to the chair back assembly so as to be attached to the waist of the human body in a self-adaptive mode, especially when a user lies down, the waist rest part descends to the proper height and can also move back and forth to the proper position so as to be attached to and bear the waist of the human body, and comfort is improved.