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14009results about "Valve arrangements" patented technology

Heart valve

A heart valve includes a valve body made of a flexible material such as pericardium. The valve body is made of two layers of material, an outer layer, and an inner layer that defines a plurality of leaflets. The leaflets of the inner layer are attached to the outer layer. In some embodiments the valve body is made by cutting a single piece of flat source tissue, folding the cut tissue and forming it into a tubular pattern having the inner and outer layers. The multi-layer valve body can be mounted on a stent for delivery within a patient's heart.
Owner:EDWARDS LIFESCI CARDIAQ

Membrane pump with stretchable pump membrane

The invention relates to membrane pumps for delivering liquids. More specifically, a pump is provided having a pump housing with a pump cavity formed between first and second wall portions thereof, and an pump membrane pump membrane having first and second membrane surfaces arranged within the pump cavity, whereby a pump chamber is provided between the first wall portion and the first membrane surface, and an actuation chamber is provided between the second wall and the second membrane surface. Inlet means comprising an inlet valve in fluid communication with the pump chamber, and outlet means comprising an outlet valve in fluid communication with the pump chamber are provided. The pump membrane has a maximum volume position, and a drained volume position in which the first membrane surface in a stretched state abuts the first wall. To drive the membrane, actuating means for periodically shifting the pump membrane between the maximum volume position and the drained volume position is provided, thereby, in a situation of use, providing a flow of fluid.
Owner:NOVO NORDISK AS

Needleless valve

A needless valve is described which avoids the suctioning problems of the prior needleless devices upon deactivation and which preferably provides a positive self-purging effect. The valve is self-purging at the end of an administration cycle, avoiding clogging of attached catheters or other devices, and ensures that substantially all of liquid received into the valve is delivered to the receiver. The valve is also extremely simple in design and easy to construct and assemble, since it consists of only three pieces. The valve has a base with a connector for fluid communication attachment to tubing or other device, a solid elongated fluid channeling rod, and an internal fluid flow conduit; a flexible hollow expandable and contractible plug fitting over and moveable along the rod; and a tubular housing fitting over the plug and attached to the base. When the valve is activated by insertion of a nozzle of a fluid source, the rod and plug wall cooperate so that as the plug retracts along the rod, it is stretched and its interior expanded. Upon deactivation, the plug contracts, the interior volume decreases, and the resiling plug wall forces residual fliud within the valve to be expelled through the outlet, purging the residual fluid from the valve. No negative pressure is formed, so no suctioning of blood or other fluid from a patient or receiver occurs.
Owner:CAREFUSION 303 INC

Method and apparatus for processing polynucleotide-containing samples

Methods and systems for processing polynucleotides (e.g., DNA) are disclosed. A processing region includes one or more surfaces (e.g., particle surfaces) modified with ligands that retain polynucleotides under a first set of conditions (e.g., temperature and pH) and release the polynucleotides under a second set of conditions (e.g., higher temperature and / or more basic pH). The processing region can be used to, for example, concentrate polynucleotides of a sample and / or separate inhibitors of amplification reactions from the polynucleotides. Microfluidic devices with a processing region are disclosed.
Owner:HANDYLAB

Splittable medical valve

A hemostatic valve couples to a sheath proximal hub having an inside and an outside surface. The hemostatic valve has a valve body having a proximal porting and end, and a distal portion and end. A passageway extends longitudinally through the valve body between the proximal and distal ends. A sealing element is positioned within the passageway. The distal portion of the valve body includes a pair of contact surfaces forming an annular gap receiving the sheath proximal hub of the sheath so that the contact surfaces sandwich the sheath proximal hub forming a seal on both the inside and outside surfaces of the hub. The valve body and the sheath proximal hub includes two oppositely placed longitudinal lines of fissure that allow the hub to be separated into two halves with the valve body.
Owner:COOK MEDICAL TECH LLC

Silicon gas injector and method of making

A gas injector tube usable in a batch thermal treatment oven including two silicon shells joined together with an adhesive formed of a fine silicon powder and a curable silica-forming agent, such as a spin-on glass, which is ultrasonically homogenized. The tube may have a gas outlet on its distal end or be sealed with a silicon cap and have side outlet holes formed along its side. The silicon injector tube may be used in combination with a silicon tower and a silicon liner so that all bulk parts within the furnace hot zone are formed of silicon.
Owner:INTEGRATED MATERIALS

Substrate processing system, substrate processing method and storage medium storing program

A substrate processing system includes a controller that outputs a control signal for controlling a substrate processing apparatus; and a software interlock component that outputs an interlock signal if a predetermined interlock condition is satisfied. In the substrate processing apparatus, a multiple number of devices of the same kind are provided and each device is selected to be either an interlocked state or a non-interlocked state with other devices. The software interlock component outputs an interlock signal to any one of the multiple number of devices of the same kind if it is determined that the multiple number of devices satisfy the predetermined interlock condition. If any one of the multiple number of devices of the same kind receives the interlock signal, the multiple number of devices are interlocked according to an instruction of the interlock signal regardless of an interlocked state or a non-interlocked state of the devices.
Owner:TOKYO ELECTRON LTD

Fluid injection

The present invention generally relates to systems and methods for the control of fluids and, in some cases, to systems and methods for flowing a fluid into and / or out of other fluids. As examples, fluid may be injected into a droplet contained within a fluidic channel, or a fluid may be injected into a fluidic channel to create a droplet. In some embodiments, electrodes may be used to apply an electric field to one or more fluidic channels, e.g., proximate an intersection of at least two fluidic channels. For instance, a first fluid may be urged into and / or out of a second fluid, facilitated by the electric field. The electric field, in some cases, may disrupt an interface between a first fluid and at least one other fluid. Properties such as the volume, flow rate, etc. of a first fluid being urged into and / or out of a second fluid can be controlled by controlling various properties of the fluid and / or a fluidic droplet, for example curvature of the fluidic droplet, and / or controlling the applied electric field.
Owner:PRESIDENT & FELLOWS OF HARVARD COLLEGE

Device, system, and method for depositing processed immiscible-fluid-discrete-volumes

ActiveUS20070039866A1Avoid pollutionFacilitates the downstream addition of aqueous reagents to the slugsValve arrangementsHeating or cooling apparatusAnalyteBiology
Various embodiments relate to systems and / or methods for sample preparation that can be used for biochemical and / or molecular biology procedures involving small volumes, for example, micro volumes or smaller. Methods and systems that can reduce sample size requirements and increase the number of samples on a substrate are provided. Samples can be applied to a plate or other appropriate substrate and can be used for, inter alia, sequencing reactions. In some embodiments, apparatuses, systems, and / or methods for charged analyte collection are provided. Charged analytes in a sample can be electrokinetically collected or extracted from a conduit through a hole formed in a sidewall of the conduit, by application of an electric field that causes the charged analytes to migrate in a direction that is transverse to the conduit.
Owner:APPL BIOSYSTEMS INC

Caulk gun pressurizing system

A device for dispensing a viscous material and a method for controlling the dispensing pressure. The device has a manually actuated control valve, that, when depressed, releases high pressure gas from the source, such as a CO2 cartridge, into a gas enclosure. An indicator signals a pre-determined pressure in the gas enclosure sufficient to forcefully dispense a viscous material from a product cartridge.
Owner:BLACK & DECKER INC

Methods and apparatus for pathogen detection and analysis

Methods and apparatus for implementing microfluidic analysis devices are provided. A monolithic elastomer membrane associated with an integrated pneumatic manifold allows the placement and actuation of dense arrays of a variety of fluid control structures, such as structures for isolating, routing, merging, splitting, and storing volumes of fluid. The fluid control structures can be used to implement a pathogen detection and analysis system including integrated immunoaffinity capture and analysis, such as polymerase chain reaction (PCR) and capillary electrophoresis (CE) analysis. An analyte solution can be input into the device and pumped through a series of immunoaffinity capture matrices in microfabricated chambers having antibodies targeted to the various classes of microbiological organisms such as bacteria, viruses and bacterial spores. The immunoaffinity chambers can capture, purify, and concentrate the target for further analysis steps.
Owner:RGT UNIV OF CALIFORNIA

Needleless valve

A needless valve is described which avoids the suctioning problems of the prior needleless devices upon deactivation and which preferably provides a positive self-purging effect. The valve is self-purging at the end of an administration cycle, avoiding clogging of attached catheters or other devices, and ensures that substantially all of liquid received into the valve is delivered to the receiver. The valve is also extremely simple in design and easy to construct and assemble, since it consists of only three pieces. The valve has a base with a connector for fluid communication attachment to tubing or other device, a solid elongated fluid channeling rod, and an internal fluid flow conduit; a flexible hollow expandable and contractible plug fitting over and moveable along the rod; and a tubular housing fitting over the plug and attached to the base. When the valve is activated by insertion of a nozzle of a fluid source, the rod and plug wall cooperate so that as the plug retracts along the rod, it is stretched and its interior expanded. Upon deactivation, the plug contracts, the interior volume decreases, and the resiling plug wall forces residual fluid within the valve to be expelled through the outlet, purging the residual fluid from the valve. No negative pressure is formed, so no suctioning of blood or other fluid from a patient or receiver occurs.
Owner:CAREFUSION 303 INC

Needle-free medical connector with expandable valve mechanism and method of fluid flow control

A needle-free medical connector includes a housing with a first port and a second port. The connector also includes a piston element defining a fluid passageway between the first and second ports. The piston element is movable between flow and non-flow positions. The piston element has an expandable section having a variable inner width and volume that forms a part of the flow path through the connector. As the piston is compressed to the flow position, the expandable section is expanded in width by movement over a flow post thereby maintaining or increasing the volume of the fluid passageway through the connector. The expandable section has a configuration permitting the continuous flow of fluid through its entirety.
Owner:CAREFUSION 303 INC

Microfluidic system including a bubble valve for regulating fluid flow through a microchannel

A microfluidic system includes a bubble valve for regulating fluid flow through a microchannel. The bubble valve includes a fluid meniscus interfacing the microchannel interior and an actuator for deflecting the membrane into the microchannel interior to regulate fluid flow. The actuator generates a gas bubble in a liquid in the microchannel when a sufficient pressure is generated on the membrane.
Owner:CYTONOMEST

Microfluidic systems and components

Microfluidic systems and components. A microfluidic system includes one or more functional units or microfluidic chips, configured to perform constituent steps in a process and interconnected to form the system. A multi-layer microfluidic system includes a separate dedicated fluid layer and dedicated electromechanical layer connected via through-holes. Electromechanical components are formed on the electromechanical layer.
Owner:THE BOARD OF TRUSTEES OF THE UNIV OF ILLINOIS
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