An aspiration control device can have an aspiration control valve and a switch, button, slider, trigger, grip, lever, rotating wheel, rotating valve,
handle or other interface for resizing the aspiration control valve. The aspiration control interface can be conveniently positioned and configured to be manipulated while simultaneously stabilizing a
catheter and / or retracting an elongated member. The aspiration control device can be integrated with a
hemostasis valve, integrated with a wire gripping device, and / or attached to an inlet, outlet, hose, pump, or
syringe in series with an aspiration flow path.