1385 results about "Lumen intima" patented technology

Systems and methods of the invention generally relate to prolonging viability of bodily tissue, especially lung tissue, through the use of an expandable accumulator to maintain a constant pressure within the lumen of the organ even during external pressure fluctuations due to, for example, flight. Systems and methods may include prolonging donor organ viability in storage through the use of an organ container that mimics the geometry and orientation of the organ in vivo.

A fluidics system includes a cassette having a saline subsystem, a contrast subsystem, and a vacuum subsystem. The fluidics system further includes a splitter and a first tubing set coupled to the cassette and splitter, the first tubing set having a single saline channel, a single contrast channel, and a single vacuum channel. The fluidics system further includes two or more hub assemblies, at least one of the two or more hub assemblies configured to have a third saline flow-path, a third contrast flow-path, and a third vacuum flow-path to provide saline, contrast and vacuum to the lumen of a catheter coupled to the at least one of the two or more hub assemblies. The fluidics system further includes a second tubing set having a plurality of tube groups, each tube group coupled to the splitter and to one of the two or more hub assemblies.

Systems and methods of the invention generally relate to prolonging viability of bodily tissue, especially lung tissue, through the use of an expandable accumulator to maintain a constant pressure within the lumen of the organ even during external pressure fluctuations due to, for example, flight. Systems and methods may include prolonging donor organ viability in storage through the use of an organ container that mimics the geometry and orientation of the organ in vivo.

Systems and methods of the invention generally relate to prolonging viability of bodily tissue, especially lung tissue, through the use of an expandable accumulator to maintain a constant pressure within the lumen of the organ even during external pressure fluctuations due to, for example, flight. Systems and methods may include prolonging donor organ viability in storage through the use of an organ container that mimics the geometry and orientation of the organ in vivo.

Rapidly insertable central catheter (“RICC”) assemblies include a RICC and an introducer. The RICC can include a soft catheter tube having an introducing aperture that opens into a primary lumen of the RICC. The introducer can include an introducer catheter including a hard catheter tube having an introducing hole that opens into a single lumen of the introducer catheter. When the RICC assembly is in a ready-to-deploy state, the introducer catheter is disposed in the primary lumen of the RICC such that a distal end of the introducer catheter extends past a distal end of the RICC. An introducer needle of the introducer can be disposed in the introducer catheter through both the introducing aperture and the introducing hole such that a beveled tip of the introducer needle extends past the distal end of the introducer catheter.

A method of inserting a catheter into a vasculature of a patient can include disposing the catheter into a housing. The housing can include a blood flash indicator, having a syringe plunger fixed to the housing and a syringe barrel slidable relative to the syringe plunger. The method can further include positioning the housing adjacent the vasculature, inserting a needle into the housing and through a lumen of the catheter until a distal tip of the needle extends from a distal end of the catheter, and accessing the vasculature via the distal tip of the needle. The method can further include sliding the syringe barrel in a proximal direction relative to the syringe plunger to create a vacuum in a lumen of the needle to thereby draw blood through the lumen of the needle and into the syringe barrel.

Intravascular imaging devices as well as methods for making and using intravascular imaging devices are disclosed. An intravascular imaging device may include a catheter shaft including a hypotube region, an imaging window region, and a distal end region having a guidewire lumen formed therein. The hypotube region may include a slotted section having a plurality of slots formed therein. The slotted section may include a plurality of discrete zones including a first zone, a second zone disposed proximal of the first zone, a third zone disposed proximal of the second zone, a fourth zone disposed proximal of the third zone, and a fifth zone disposed proximal of the fourth zone. The first zone may have a constant flexural rigidity. One or more of the second zone, the third zone, and the fifth zone may have a flexural rigidity that varies along a length thereof. An imaging core may be within the catheter shaft.

Provided herein are imaging systems for a patient including an imaging probe and an imaging assembly. The imaging probe includes an elongate shaft with a rotatable optical core positioned within a lumen of the elongate shaft. The imaging probe further includes an optical assembly to direct light to tissue to be imaged and to collect reflected light from the tissue to be imaged. The system further includes an imaging assembly optically coupled to the imaging probe. The system further includes a processing unit with a processor and a memory coupled to the processor, and the memory stores instructions for the processor to perform an algorithm. The system records image data based on the reflected light collected by the optical assembly, such that the image data comprises data collected from a segment of a blood vessel during a pullback procedure. The algorithm can analyze the image data.

Embodiments described herein relate to an implant delivery system for delivering an implant for reducing heart valve regurgitation. The implant delivery system may include an implant catheter disposed in an inner lumen of a guide catheter. The implant catheter may include one or more hypotubes disposed therein, each hypotube configured to receive an elongate member such as a braided tether. A distal end of the implant catheter may be coupled to an implant holder configured to receive the implant. The implant holder may define one or more channels, each channel configured to receive a portion of a respective elongate member. The elongate members configured to couple the implant to the implant holder and transition the implant between configurations. The implant configured to be disposed around a portion of a leaflet of a heart valve to improve coaptation of the heart valve.

The present invention discloses a device, which includes a catheter and an end effector. The size and structure of at least a portion of the catheter are configured to be assembled in the inner cavity of the cardiovascular system. The end effector is positioned at the distal end of the catheter. The end effector includes a panel, a plurality of mapping electrodes positioned on a first surface of the panel, and a plurality of ablation electrodes positioned on the first surface of the panel. The mapping electrodes are configured to sense the potential in the tissue contacting the mapping electrodes. The ablation electrodes are operable to ablate the tissue contacting the ablation electrodes.

Embodiments described herein relate to an implant delivery system for delivering an implant for reducing heart valve regurgitation. The implant delivery system may include an implant catheter disposed in an inner lumen of a guide catheter. The implant catheter may include one or more hypotubes disposed therein, each hypotube configured to receive an elongate member such as a braided tether. A distal end of the implant catheter may be coupled to an implant holder configured to receive the implant. The implant holder may define one or more channels, each channel configured to receive a portion of a respective elongate member. The elongate members configured to couple the implant to the implant holder and transition the implant between configurations. The implant configured to be disposed around a portion of a leaflet of a heart valve to improve coaptation of the heart valve.

An expandable introducer apparatus comprising an inner tubular layer comprising an inner lumen and a radially expandable region extending along an elongated axis of the inner lumen and configured to at least partially radially expand relative to the elongated axis from a contracted orientation to an expanded orientation. An outer tubular layer comprising an inner surface bonded to the inner tubular layer, wherein a distal segment of the inner tubular layer extends beyond a distal end of the outer tubular layer. A flexible tubular member comprising a bonded region and a flexible region, wherein an inner surface of the bonded region is bonded to an outer surface of the distal segment of the inner tubular layer, and the flexible region is not bonded to the radially expandable region of the inner tubular layer.

Systems, devices, and methods described herein relate to catheter devices for therapy delivery. In some embodiments, a catheter device includes a shaft and a needle, where the shaft defines a lumen configured to slidably receive the needle such that the needle can be advanced distally beyond the shaft to penetrate into a tissue site. The shaft further including a first electrode, and the needle including a second electrode, where the first and second electrodes are configured to deliver electroporation to the tissue site.

Intravascular imaging devices as well as methods for making and using intravascular imaging devices are disclosed. An intravascular imaging device may include a catheter shaft including a proximal region, an imaging window region, and a distal end region having a guidewire lumen formed therein. The catheter shaft may include a telescoping assembly having a telescope hub configured to be secured to a pullback assembly. The telescope hub may include a proximal flange, a loading region disposed distal of the proximal flange, and a grip region disposed distal of the loading region. The grip region may have a non-circular cross-sectional shape. An imaging core may be disposed within the catheter shaft.

A system for preparation of an implant and ab interno insertion of the implant into an eye including a handle having one or more actuators and an elongated shaft having an outer sheath and an elongate member positioned within a lumen of the tubular outer sheath. The system includes a recess sized for holding a patch of material fixed relative to the handle and a cutting member movable relative to the handle and to the recess. The cutting member cuts the patch of material into an implant as the cutting member moves towards a cutting configuration. The implant, once cut, is axially aligned with the lumen of the tubular outer sheath. The inner elongate member is movable relative to the tubular outer sheath to advance the implant into a deployment position in the lumen of the tubular outer sheath for delivery into the eye. Related devices and methods are provided.

A device for providing a passage between a first and second heart chamber is provided. The device includes a middle region having first and second ends, a lumen extending therethrough having a longitudinal axis, a first end region coupled to the first end, and a second end region coupled to the second end. The first end region may be delivered in the first heart chamber in a compressed state and transitioned to a deployed state, the first end region being deformable such that portions of the first end region are expandable to different angles relative to the longitudinal axis. The second end region may be delivered in the second heart chamber in a compressed state and transitioned to a deployed state therein, the second end region being deformable such that portions of the second end region are expandable to different angles relative to the longitudinal axis.

An aorta intervention catheter device for heart failure comprises a catheter and a bag body arranged at one end of the catheter, an elastic diaphragm is arranged in the bag body, an inner cavity of the bag body is divided into a blood chamber and an air chamber by the elastic diaphragm, the blood chamber is communicated with the catheter, an exhaust assembly is arranged on the bag body, and the air chamber is connected with an air source connector arranged on the bag body; the other end of the catheter is a proximal end, first guide films which are staggered at intervals and inclined towards one side of the proximal end and second guide films which are inclined towards a distal end are arranged on the inner wall of the catheter, and first guide holes and second guide holes which correspond to the first guide films and the second guide films and are communicated with an inner cavity of the catheter are respectively formed in the outer wall of the catheter; the proximal side of the second guide film is provided with at least one set of third guide films which are fixed to the inner wall of the catheter, incline towards the distal end and are tightly attached to each other to be closed. The aorta is directly intervened to enter the heart, and coronary artery blood perfusion is increased in the diastolic period; the left ventricular post-load is reduced in the systolic period, and the heart failure can be more directly treated.

A lumen organ model and an endoscope training system are provided. A luminal organ model (3) is provided with: a model body (11) comprising a hollow lumen body having a lumen surface that simulates at least the lumen of a luminal organ such as the stomach, the large intestine, the bladder, the paranasal sinus, or the uterus; a light source device (13) that emits light in a light-emitting region disposed at at least one predetermined observation site corresponding to a training purpose on the lumen surface of a model body (11) comprising a lumen; and a processor (27) that selectively switches light-emitting regions that emit light by controlling the light source device (13).

The invention provides a medical lumen instrument disinfection method which comprises the following steps: acquiring a three-dimensional digital model of a lumen instrument through scanning equipment, extracting lumen data and generating standardized structure parameters; constructing a docking interface template library according to the standardized structure parameters, and generating an initial interface model; loading an initial interface model and inner cavity data through fluid mechanics simulation software, simulating flow distribution of a sterilizing agent and determining flow blocking and leakage positions; geometric parameters of the initial interface model are adjusted according to flow blocking and leakage positions, and a docking system model with enhanced adaptability is generated; calculating the flow velocity and pressure parameters of a sterilizing agent according to the suitability-enhanced docking system model and the inner cavity data, and generating flow parameter configuration; the injection rate and the medium viscosity are adjusted according to the flow parameter configuration and the inner cavity attribute, and a sterilization parameter set is generated; and driving the docking system model to execute a sterilization operation through the sterilization parameter set, collecting coverage distribution data and generating an optimization control scheme.

Devices and methods for providing a pathway for fluid to flow around a main lumen of a guide catheter are disclosed. As one example, a delivery apparatus can include a handle including an outer housing and a flush port coupled to the outer housing, a shaft extending distally from the handle, and a main lumen extending axially through the shaft, where the main lumen is fluidly coupled to the flush port via a flush lumen extending between the flush port and the main lumen. The delivery apparatus can further include at least one axially extending channel fluidly coupled to and radially offset from the main lumen, the channel extending between a first location that is adjacent to the flush lumen and a second location that is adjacent to a distal end of the shaft.

A two-way valve and a pulsatile percutaneous ventricular assist device using same. The two-way valve comprises: a valve body (1) with an inner cavity (10) passing through, the inner cavity being provided with a proximal port (1a) and a distal port (1b), and the valve body (1) being provided with an open window (1c) in communication with the inner cavity (10) and the outside of the valve body (1); and a valve flap (2) arranged in the inner cavity (10) and rotationally connected to the valve body (1), the valve flap (2) comprising a first valve leaf (21), a second valve leaf (22), and a third valve leaf (23), which are connected at an obtuse angle, the first valve leaf (21) being arranged at the open window (1c), the second valve leaf (22) being arranged on one side close to the inner cavity (10) at one end of the first valve leaf (21) close to the proximal port (1a), and the third valve leaf (23) being arranged on one side close to the inner cavity at one end of the first valve leaf close to the distal port (1b). The valve flap (2) is impacted by blood flow axially flowing in the inner cavity (10) and is rotationally switched back and forth between an open position and a closed position. In the open position, the three valve leaves together partition the proximal port (1a) and the distal port (1b), and the open window (1c) is opened and in communication with the distal port (1b). In the closed position, the first valve leaf (21) closes the open window (1c), and the proximal port (1a) is in communication with the distal port (1b), thereby achieving better switching response and sealing effects.

An electrode lead comprising an elongate lead body having a proximal end, a distal end and a plurality of electrical conductors, a biologically compatible, elastic, electrically insulative nerve cuff body that is associated with the distal end of the lead body, is configured to be circumferentially disposed around a nerve, has a pre-set furled state that defines an inner lumen and is movable to an unfurled state, a plurality of electrically conductive contacts carried by the nerve cuff body and electrically associated with the electrical conductors, and an inflatable nerve cuff straightener associated with the nerve cuff body and configured to at least substantially straighten the nerve cuff body when in a fully inflated state.

An orientable intravascular device having a “twelve o'clock” marker on a proximal and distal end for treating an aneurysm, including a packaging catheter with an identical fixed non-round shaped inner lumen, a pusher wire having an occlusion device releasably disposed on the distal end of said pusher wire, preloaded at a fixed circumferential orientation, with corresponding markers on the outside of said packaging catheter, a hub having an inner lumen that is shaped to marry with the outer lumen of the packaging catheter to deliver a delivery wire and occlusion stent in a predicted orientation, and maintaining such orientation as the wire and stent are advanced through said delivery catheter, and while said delivery catheter is withdrawn. Methods of using same are disclosed.

The present technology includes patient-specific spinal fusion devices, which may include an interbody implant that is designed to be positioned within a disc space between two vertebral bodies and one or more fixation elements that can anchor the interbody implant to the vertebral bodies. The fusion devices include one or more retention mechanisms for retaining the fixation elements within corresponding lumens or bore holes extending through the interbody implant. Methods for designing and manufacturing patient-specific spinal fusion devices are also described herein.

An IV device assembly may include a lumen forming a fluidic channel within the IV device assembly. The lumen may be fluidically coupled to a vascular access device (VAD) coupler via a funnel coupler, and an IV device assembly coupler at a proximal end of the lumen. The IV device assembly may also include one or more of the following: a collapsible sleeve formed coaxially around a first portion of the lumen and mechanically coupled to the funnel coupler, a probe formed along a second portion of the lumen within the collapsible sleeve and into the VAD coupler, a translation handle that translates the probe out of a distal end of the VAD coupler, and a fixed grip formed around the lumen to maintain a position of the IV device assembly relative to the translation handle.

A sheath delivery system comprises an access device for insertion of one or more wires to extend in first and second directions within a blood vessel. The access device can include an elongated member with a lumen between a distal tip and proximal end, the lumen oriented to exit a patient, a footplate having a bore extending therethrough the footplate and configured to translate within the lumen between an initial state along the lumen and a rotated state anchoring the access device within a blood vessel, a first wire port through which a first wire enters and advances past the footplate into the blood vessel in a first direction, and a second wire port configured to guide a second wire into the lumen so that the second wire passes through the lumen and through the hollow bore of the footplate such that the second wire advances in the second direction.

A tissue treatment system and method of using the tissue treatment system determines a size of a body lumen, or a neuromodulation parameter corresponding to the size of the body lumen. The tissue treatment system fills a balloon with a fluid when the balloon is within a body lumen. A fluid parameter of the fluid is detected over a period of time. A parameter curve of the fluid parameter is determined. The parameter curve includes the fluid parameter versus an independent variable over the period of time. The parameter curve includes inflections that correspond to changes in the fluid parameter. Based on the inflections, the system can determine the body lumen size or the neuromodulation parameter. Other embodiments are also described and claimed.

A rod shape visualisation device (1) is proposed for providing information on the desired shape of a posterior spinal rod during a bending process whilst being arranged in a sterile operation area. The rod shape visualisation device (1) comprises: (a) a sterile case (10) comprising a housing portion (11) including an entrance aperture (12) and a cover (13). sized and shaped to seal the entrance aperture (12). the sterile case (10) further comprising an inner lumen (14) configured to come in contact with non-sterile or sterile objects. and (b) a non-sterile or sterile visualisation template (40) comprising a displaying side providing information on the desired shape of a posterior rod. The rod shape visualisation device (1) defines a first. open state in which the cover (13) is open, and a second. closed state in which the cover (13) is closed. wherein in the closed state. the displaying side of the visualisation template (40) is visibly arranged in the inner lumen (14).

An electrode that includes an elongate lead body and a nerve cuff. The nerve cuff may include a biologically compatible, elastic, electrically insulative cuff body configured to be circumferentially disposed around a nerve, first and second relatively wide electrically conductive contacts carried by the cuff body that are spaced from one another in the length direction and that extend in the width direction to such an extent that they extend completely around the cuff body inner lumen when the cuff body is in the pre-set furled shape, and a plurality of relatively narrow electrically conductive contacts carried by the cuff body that are spaced from one another in the width direction and are located between the first and second relatively wide electrically conductive contacts.

The invention relates to a simulation-based target removal area determination method and device. The method comprises the following steps: acquiring a heart simulation model and corresponding blood flow field information; according to the left heart lumen model and the blood flow field information, determining a first target area in the ventricular septum model; stress calculation is carried out according to the ventricular septum model, and a second target area in the ventricular septum model is determined; determining an initial target area according to the first target area and the second target area; according to the ventricular septum model, determining the thickness range of the initial target area at the end of contraction; determining a target cutting thickness according to a preset basic thickness and a thickness range; according to the heart simulation model, the initial target area, the target resection thickness and the blood flow field information, a first target resection area is determined. By adopting the method, the cardiac muscle tissue area needing to be cut off can be accurately determined.