928 results about "Lumen intima" patented technology

Systems and methods of the invention generally relate to prolonging viability of bodily tissue, especially lung tissue, through the use of an expandable accumulator to maintain a constant pressure within the lumen of the organ even during external pressure fluctuations due to, for example, flight. Systems and methods may include prolonging donor organ viability in storage through the use of an organ container that mimics the geometry and orientation of the organ in vivo.

Systems and methods of the invention generally relate to prolonging viability of bodily tissue, especially lung tissue, through the use of an expandable accumulator to maintain a constant pressure within the lumen of the organ even during external pressure fluctuations due to, for example, flight. Systems and methods may include prolonging donor organ viability in storage through the use of an organ container that mimics the geometry and orientation of the organ in vivo.

Systems and methods of the invention generally relate to prolonging viability of bodily tissue, especially lung tissue, through the use of an expandable accumulator to maintain a constant pressure within the lumen of the organ even during external pressure fluctuations due to, for example, flight. Systems and methods may include prolonging donor organ viability in storage through the use of an organ container that mimics the geometry and orientation of the organ in vivo.

Provided herein are imaging systems for a patient including an imaging probe and an imaging assembly. The imaging probe includes an elongate shaft with a rotatable optical core positioned within a lumen of the elongate shaft. The imaging probe further includes an optical assembly to direct light to tissue to be imaged and to collect reflected light from the tissue to be imaged. The system further includes an imaging assembly optically coupled to the imaging probe. The system further includes a processing unit with a processor and a memory coupled to the processor, and the memory stores instructions for the processor to perform an algorithm. The system records image data based on the reflected light collected by the optical assembly, such that the image data comprises data collected from a segment of a blood vessel during a pullback procedure. The algorithm can analyze the image data.

Embodiments described herein relate to an implant delivery system for delivering an implant for reducing heart valve regurgitation. The implant delivery system may include an implant catheter disposed in an inner lumen of a guide catheter. The implant catheter may include one or more hypotubes disposed therein, each hypotube configured to receive an elongate member such as a braided tether. A distal end of the implant catheter may be coupled to an implant holder configured to receive the implant. The implant holder may define one or more channels, each channel configured to receive a portion of a respective elongate member. The elongate members configured to couple the implant to the implant holder and transition the implant between configurations. The implant configured to be disposed around a portion of a leaflet of a heart valve to improve coaptation of the heart valve.

Embodiments described herein relate to an implant delivery system for delivering an implant for reducing heart valve regurgitation. The implant delivery system may include an implant catheter disposed in an inner lumen of a guide catheter. The implant catheter may include one or more hypotubes disposed therein, each hypotube configured to receive an elongate member such as a braided tether. A distal end of the implant catheter may be coupled to an implant holder configured to receive the implant. The implant holder may define one or more channels, each channel configured to receive a portion of a respective elongate member. The elongate members configured to couple the implant to the implant holder and transition the implant between configurations. The implant configured to be disposed around a portion of a leaflet of a heart valve to improve coaptation of the heart valve.

An expandable introducer apparatus comprising an inner tubular layer comprising an inner lumen and a radially expandable region extending along an elongated axis of the inner lumen and configured to at least partially radially expand relative to the elongated axis from a contracted orientation to an expanded orientation. An outer tubular layer comprising an inner surface bonded to the inner tubular layer, wherein a distal segment of the inner tubular layer extends beyond a distal end of the outer tubular layer. A flexible tubular member comprising a bonded region and a flexible region, wherein an inner surface of the bonded region is bonded to an outer surface of the distal segment of the inner tubular layer, and the flexible region is not bonded to the radially expandable region of the inner tubular layer.

A system for preparation of an implant and ab interno insertion of the implant into an eye including a handle having one or more actuators and an elongated shaft having an outer sheath and an elongate member positioned within a lumen of the tubular outer sheath. The system includes a recess sized for holding a patch of material fixed relative to the handle and a cutting member movable relative to the handle and to the recess. The cutting member cuts the patch of material into an implant as the cutting member moves towards a cutting configuration. The implant, once cut, is axially aligned with the lumen of the tubular outer sheath. The inner elongate member is movable relative to the tubular outer sheath to advance the implant into a deployment position in the lumen of the tubular outer sheath for delivery into the eye. Related devices and methods are provided.

A lumen organ model and an endoscope training system are provided. A luminal organ model (3) is provided with: a model body (11) comprising a hollow lumen body having a lumen surface that simulates at least the lumen of a luminal organ such as the stomach, the large intestine, the bladder, the paranasal sinus, or the uterus; a light source device (13) that emits light in a light-emitting region disposed at at least one predetermined observation site corresponding to a training purpose on the lumen surface of a model body (11) comprising a lumen; and a processor (27) that selectively switches light-emitting regions that emit light by controlling the light source device (13).

Devices and methods for providing a pathway for fluid to flow around a main lumen of a guide catheter are disclosed. As one example, a delivery apparatus can include a handle including an outer housing and a flush port coupled to the outer housing, a shaft extending distally from the handle, and a main lumen extending axially through the shaft, where the main lumen is fluidly coupled to the flush port via a flush lumen extending between the flush port and the main lumen. The delivery apparatus can further include at least one axially extending channel fluidly coupled to and radially offset from the main lumen, the channel extending between a first location that is adjacent to the flush lumen and a second location that is adjacent to a distal end of the shaft.

The present technology includes patient-specific spinal fusion devices, which may include an interbody implant that is designed to be positioned within a disc space between two vertebral bodies and one or more fixation elements that can anchor the interbody implant to the vertebral bodies. The fusion devices include one or more retention mechanisms for retaining the fixation elements within corresponding lumens or bore holes extending through the interbody implant. Methods for designing and manufacturing patient-specific spinal fusion devices are also described herein.

A tissue treatment system and method of using the tissue treatment system determines a size of a body lumen, or a neuromodulation parameter corresponding to the size of the body lumen. The tissue treatment system fills a balloon with a fluid when the balloon is within a body lumen. A fluid parameter of the fluid is detected over a period of time. A parameter curve of the fluid parameter is determined. The parameter curve includes the fluid parameter versus an independent variable over the period of time. The parameter curve includes inflections that correspond to changes in the fluid parameter. Based on the inflections, the system can determine the body lumen size or the neuromodulation parameter. Other embodiments are also described and claimed.

The invention relates to a simulation-based target removal area determination method and device. The method comprises the following steps: acquiring a heart simulation model and corresponding blood flow field information; according to the left heart lumen model and the blood flow field information, determining a first target area in the ventricular septum model; stress calculation is carried out according to the ventricular septum model, and a second target area in the ventricular septum model is determined; determining an initial target area according to the first target area and the second target area; according to the ventricular septum model, determining the thickness range of the initial target area at the end of contraction; determining a target cutting thickness according to a preset basic thickness and a thickness range; according to the heart simulation model, the initial target area, the target resection thickness and the blood flow field information, a first target resection area is determined. By adopting the method, the cardiac muscle tissue area needing to be cut off can be accurately determined.

The invention discloses a medical catheter surface strong interface bonding hydrogel coating method based on subsurface initiated polymerization. The method comprises the steps that firstly, a mixed solvent of an organic solvent and water is adopted for conducting swelling pretreatment on the surface of a catheter base material, so that polymer chains on the surface layer of the base material are relaxed; a solution containing initiator molecules is injected into the inner cavity of the catheter, so that the initiator is diffused and anchored in the subsurface area of the base material; preparing a hydrogel monomer solution containing a hydrophilic monomer, a cross-linking agent and a catalyst, and pouring the hydrogel monomer solution into the inner cavity of the catheter; and finally, sealing the two ends of the conduit, and initiating polymerization reaction under a specific temperature condition, so that the initiator anchored on the subsurface is decomposed to generate free radicals. The hydrogel coating and the catheter base material form a double combination effect of physical interlocking and chemical bonding through a subsurface initiated polymerization mechanism, the firmness and stability of the coating are remarkably improved, and the method is particularly suitable for modification of the inner surfaces of various medical catheters with complex structures.

A delivery system for delivering an implant having both a rigid portion and a flexible portion to a body lumen. The delivery system includes an outer tubular member and an inner tubular member slidably disposed within the lumen of the outer tubular member. The inner tubular member includes at least one opening positioned in a side wall adjacent to a distal end region. An expandable implant, including a rigid portion and a flexible portion, is disposed about the outer surface of the inner tubular member. A distal portion of a thread is wrapped around the flexible portion of the implant and configured to maintain the flexible portion in a radially collapsed configuration during delivery of the implant. A distal end region of the outer tubular member is disposed around the rigid portion of the implant to maintain the rigid portion in a radially collapsed configuration during delivery of the implant.

A stent, such as transluminal stent, is disclosed. The stent includes a tubular member with a proximal end, a distal end, and a central portion therebetween. The elongate tubular member comprises a scaffolding forming a plurality of cells and defining a lumen of the elongate tubular member. A proximal portion of the tubular member forms a retention member, wherein the diameter of the retention member is greater than the diameter of the central portion, and wherein a proximal end of the retention member includes an area of increased scaffolding density.

An extravascular system is provided which includes a catheter adapter having a blood control septum configured to control flow of a fluid through the catheter adapter, the catheter adapter further having a catheter configured for intravenous insertion. The extravascular system further includes a septum activator slidably inserted within the catheter adapter and configured for advancement through the blood control septum to provide a fluid pathway through the blood control septum. Further still, the extravascular system includes an external safety mechanism comprising a needle hub and a needle shield interconnected via a tether, wherein the needle shield includes a safety clip that is configured to retain a sharpened end of the introducer needle within the needle shield. Some implementations further comprise an access port forming a portion of the catheter adapter and providing selective access to the lumen of the catheter adapter.

The invention discloses a locking structure balloon catheter system for trigeminal neuralgia and a using method of the locking structure balloon catheter system, and relates to the technical field of balloon catheters. The balloon is allowed to be filled only after the balloon catheter is conveyed to the preset position, so that the situation that the balloon is filled in advance due to misoperation is prevented, and the risk of misoperation is effectively reduced. The system comprises a puncture needle, a balloon catheter and a locking structure, the puncture needle is used for establishing a channel; the balloon catheter comprises a filling catheter, a balloon and a handle Luer connector assembly; the balloon is connected to the far end of the filling catheter, and the two ends of the handle Luer connector assembly are connected with the filling catheter and the injector respectively. The locking structure comprises an elastic sleeve which sleeves the outer wall of the filling guide pipe, and two ends of the elastic sleeve are fixedly connected to the outer wall of the filling guide pipe; when the elastic sleeve is located in the inner cavity of the puncture needle, the elastic sleeve deforms, and a fluid channel filling the catheter is closed; when the elastic sleeve is separated from the puncture needle inner cavity, the elastic sleeve restores to open the fluid channel; the invention further discloses a using method of the balloon catheter system.

A surgical system includes an ultrasound device and a surgical instrument. The ultrasound device includes a shaft having a body defining a longitudinal axis and including a lumen extending coaxially therethrough, and an ultrasound sensor assembly configured to enable ultrasound imaging of a field of view. The ultrasound sensor assembly is disposed at a distal end portion of the body of the shaft, offset relative to the longitudinal axis, and oriented such that the field of view is offset relative to the longitudinal axis. The surgical instrument is configured for removable insertion through the lumen of the body of the shaft and to extend distally from the distal end portion of the body of the shaft.

Medical devices and systems are described. The medical device may include a handle that includes a hub, a grip portion, and an arm. The hub may define a lumen having a proximal opening. The arm may extend proximally from the hub and may be coupled to a member slidable or rotatable relative to the arm. The grip portion may extend transverse to the lumen of the hub. The grip portion may be configured to receive a palm of a user's hand while a thumb of the user's hand controls sliding or rotation of the member.

A delivery system and method are described that include a catheter and an active wire. The catheter has a catheter body that defines a primary lumen and a secondary lumen therethrough, which are spaced apart from each other. A distal end of the catheter body is configured to be located within a chamber of a heart proximate to myocardial tissue at a site of interest (SOI). The primary lumen has a greater cross-sectional size than the secondary lumen. The primary lumen is configured to receive at least a portion of an IMD therein and to permit the portion of the IMD to move relative to the catheter. The active wire is configured to extend through the secondary lumen so that a distal end of the active wire projects beyond the distal end of the catheter body to pierce the myocardial tissue at the SOI.

The application provides a perfusion balloon catheter with a one-way valve, comprising: a balloon body part; the balloon body part comprises an inner lumen tube and a plurality of balloons arranged around the outer surface of the inner lumen tube; the distal balloon tube leg of the plurality of balloons is in contact with the tube wall of the inner lumen tube; a one-way valve is arranged between the inner lumen tube and the balloon part of the balloon. Compared with the prior art, the perfusion balloon catheter provided by the application is formed by a plurality of balloon clusters, and after expansion, a hollow cylindrical shape is formed, and a one-way valve is arranged in the cavity, which is used to simulate the leaflets in the heart valve, and the one-way valve is enabled after the balloon is opened, without the need for switching operation, and the structure is stable, and the function of the leaflets can be realized for multiple times; in addition, the design of the cluster balloon can reduce the difficulty of the balloon forming process while meeting the expected function.

Devices and methods for equalizing pressure in a main lumen of a guide sheath shaft are disclosed. As one example, a delivery apparatus can include a handle and a shaft extending within and distally from the handle. The shaft has a main lumen, and a distal end portion of the shaft includes one or more holes that extend through a wall of the shaft, between the main lumen and an exterior of the shaft. The one or more holes are spaced axially away from a distal end of the shaft.

A replacement heart valve implant includes an expandable framework including a tubular wall comprising a plurality of interconnected struts and defining a central lumen, wherein the wall includes inflow and outflow ends, and a plurality of commissure posts. A plurality of valve leaflets is secured to the commissure posts. The framework may include a plurality of native leaflet clamps extending upstream from the outflow end, wherein the leaflet clamps are configured to pinch native leaflets of the native heart valve against the wall. The framework may include a plurality of native commissure clamps extending upstream from the commissure posts, wherein the commissure clamps are configured to pinch native commissures of the native heart valve. The framework may include a plurality of native leaflet clamps extending upstream from the commissure posts, wherein the leaflet clamps are configured to pinch native leaflets of the native heart valve against the wall.

The invention provides a microcatheter with a braid layer. The microcatheter comprises a catheter body and a tip part, the tube body is provided with a guide wire inner cavity capable of slidably receiving a guide wire; the tip part is provided with a cavity communicated with the inner cavity of the guide wire; the inner layer forms a guide wire inner cavity, the spring layer is wound around the inner layer in a winding mode and arranged in the length direction of the inner layer, the braid layer is arranged on the outer side of the spring layer and completely surrounds the spring layer, the polymer layer covers the outer side of the braid layer, and the braid layer extends into the tip part. Under the condition, the overlapped part of the tip part and the braid layer can have better bending resistance, so that the microcatheter with the braid layer, which is provided by the invention, is high in pushing property, high in flexibility and excellent in tension resistance and bending resistance, can be provided.

The invention relates to a head end active advancing catheter which comprises a catheter body, an inflatable balloon, a fluid backflow channel, a tail end catheter cavity opening and closing device and a power pump. The inflatable balloon is arranged on the inner side of the head end of the catheter; the fluid backflow passage is arranged in the catheter wall, and the catheter center cavity is communicated with the fluid backflow passage at the catheter head end; when the inner cavity at the head end of the catheter is closed by the inflatable balloon, the central cavity is only communicated with the fluid backflow channel; the tail end of the catheter is provided with a tail end lumen opening and closing device used for blocking a lumen outer opening. The guide pipe central cavity is connected with a medium hose; the medium hose is connected with a power pump; when the head end and the tail end of the central cavity of the catheter are closed by the inflatable balloon and the tail end catheter cavity opening and closing device respectively, a fluid medium is pumped into the central cavity through the power pump, the fluid medium flows back through the fluid backflow channel, and active advancing of the head end of the catheter is achieved through counter-acting force.

A system for treating an eye comprising a tissue stored within a lumen of an elongated cannula, the tissue comprises scleral, amniotic membrane, or acellular biomatrix tissue and having an elongated form factor. Related devices, systems, and methods are provided.

Systems and methods for mitigating backflow in subcutaneous infusion devices are disclosed. A medical device can include base having a surface configured to be placed against a patient's skin and a subcutaneous assembly coupled to the base and configured to be inserted through the patient's skin when the surface of the base is placed against the patient's skin. The subcutaneous assembly includes an infusion cannula defining a lumen extending therethrough and configured to infuse fluid therethrough, and a sensor configured to sense a biological analyte. An expandable member (e.g., a swellable material) is coupled to a radially outer surface of the subcutaneous assembly. The expandable member is configured to expand in a radially outward direction when in the presence of bodily fluid, thereby at least partially blocking a flow path from the distal end portion of the infusion cannula to the sensor.

Systems and methods of the invention generally relate to prolonging viability of bodily tissue, especially lung tissue, through the use of an expandable accumulator to maintain a constant pressure within the lumen of the organ even during external pressure fluctuations due to, for example, flight. Systems and methods may include prolonging donor organ viability in storage through the use of an organ container that mimics the geometry and orientation of the organ in vivo.