1276 results about "Body fluid" patented technology

A system for the hypothermic transport of biological samples, such as tissues, organs, or body fluids. The system includes a self-purging preservation apparatus to suspend a sample in preservation fluid and perfuse a tissue with preservation fluid. The self-purging preservation apparatus is placed in an insulated transport container having a cooling medium. When assembled, the system allows for transport of biological samples for extended periods of time at a stable temperature.

A system for the hypothermic transport of biological samples, such as tissues, organs, or body fluids. The system includes a self-purging preservation apparatus to suspend a sample in preservation fluid and perfuse a tissue with preservation fluid. The self-purging preservation apparatus is placed in an insulated transport container having a cooling medium. When assembled, the system allows for transport of biological samples for extended periods of time at a stable temperature.

A system for the hypothermic transport of biological samples, such as tissues, organs, or body fluids. The system includes a self-purging preservation apparatus to suspend a sample in preservation fluid and perfuse a tissue with preservation fluid. The self-purging preservation apparatus is placed in an insulated transport container having a cooling medium. When assembled, the system allows for transport of biological samples for extended periods of time at a stable temperature.

A bodily-fluid transfer device includes a housing, a pre-sample reservoir, and an actuator. The housing defines an inner volume between a substantially open proximal end portion and a distal end portion that includes a port couplable to a lumen-defining device. The pre-sample reservoir is fluidically couplable to the port to receive a first volume of bodily fluid. The actuator is at least partially disposed in the inner volume and has a proximal end portion that includes an engagement portion and a distal end portion that includes a sealing member. The engagement portion is configured to allow a user to selectively move the actuator between a first configuration such that bodily fluid can flow from the port to the pre-sample reservoir, and a second configuration such that bodily fluid can flow from the port to a sample reservoir defined at least in part by the sealing member and the housing.

An apparatus includes a cannula assembly, a housing, a fluid reservoir, a flow control mechanism, and an actuator. The housing includes an inlet port removably coupled to the cannula assembly and defines an inner volume. The fluid reservoir is fluidically coupled to the housing and configured to receive and isolate a volume of bodily fluid from a patient. The flow control mechanism is at least partially disposed in the inner volume. The actuator is operably coupled to the flow control mechanism and is configured to move the flow control mechanism between a first configuration, in which bodily fluid can flow, via a fluid flow path defined by the flow control mechanism, from the cannula assembly, through the inlet port and into the fluid reservoir, to a second configuration, in which the fluid reservoir is fluidically isolated from the cannula assembly.

The invention provides an intelligent tumor nursing monitoring system. The intelligent tumor nursing monitoring system comprises a data acquisition module, a data processing module, a dynamic evaluation module, a multi-stage early warning module and a self-adaptive control module. The data acquisition module acquires physiological sign data, tumor local image data and body fluid biochemical data of a patient in real time through a multi-source biosensor. And the data processing module performs space-time alignment, noise suppression and cross-modal feature association on the multi-modal data to generate a comprehensive feature map. The dynamic evaluation module calculates the tumor progress rate and the complication risk coefficient based on the map, and generates a personalized risk prediction curve. And the multi-stage early warning module triggers an early warning signal according to the curve and generates a risk traceability report. And the adaptive control module generates a personalized scheme based on the early warning signal and the traceability report and controls the medical equipment to execute closed-loop feedback adjustment. The nursing quality and the treatment effect of tumor patients can be improved, and the medical risk is reduced.

A system for the hypothermic transport of biological samples, such as tissues, organs, or body fluids. The system includes a self-purging preservation apparatus to suspend a sample in preservation fluid and perfuse a tissue with preservation fluid. The self-purging preservation apparatus is placed in an insulated transport container having a cooling medium. When assembled, the system allows for transport of biological samples for extended periods of time at a stable temperature.

A system for the hypothermic transport of biological samples, such as tissues, organs, or body fluids. The system includes a self-purging preservation apparatus to suspend a sample in preservation fluid and perfuse a tissue with preservation fluid. The self-purging preservation apparatus is placed in an insulated transport container having a cooling medium. When assembled, the system allows for transport of biological samples for extended periods of time at a stable temperature.

The invention relates to the technical field of intraoperative bleeding amount monitoring, and provides an intelligent intraoperative bleeding amount monitoring and alarming method and system.The method comprises the steps that during an operation, blood, body fluid and cleaning fluid in an operation area are cleaned in time through a suction bottle and gauze; after the gauze is used, the absorbed liquid is partially screwed out and flows into the liquid collecting tank; weight changes of the suction bottle and the gauze storage area are detected in real time respectively, signals are transmitted to the data processing module, the concentration of hemoglobin in the two kinds of liquid is detected, the concentration of blood in the liquid is calculated, and the concentration of the hemoglobin in the liquid is calculated by combining the amount of the liquid sucked by the suction bottle and the amount of the liquid taken out by the gauze in real time. The amount of blood brought out by the gauze and the amount of blood sucked out by the suction bottle are calculated in real time, the real-time bleeding amount of a patient in an operation is obtained, and when the real-time bleeding amount reaches a threshold value, early warning is given out. The problems that errors are large in a traditional method, and particularly in a large amount of blood loss or a complex operation scene, the blood loss dynamic state is difficult to master timely and accurately are solved.

The invention discloses a blood, urine and body fluid collecting, detecting, analyzing and uploading system based on multi-sensor integration, which comprises the following modules: a blood collecting module for collecting a blood sample; the urine collection module is used for detecting urine; the body fluid collecting module is used for detecting body fluid; the data processing module is used for preprocessing data; the feature extraction and classification module is used for constructing a multi-modal feature matrix based on a neural structure search network, a support vector machine and a random forest algorithm; the anomaly detection module is used for generating a weighted anomaly score in combination with an isolated forest and a depth anomaly detection model; the time sequence analysis module is used for analyzing the health trend by using a variational auto-encoder-generative adversarial network; the health portrait and risk assessment module is used for constructing a health map by adopting a graph convolutional network; and the encryption and uploading management module is used for encrypting by using AES and RSA and managing the data access authority based on the intelligent contract. According to the invention, a multi-modal sensor and an intelligent algorithm are integrated, and collection, detection, analysis, encryption and uploading of blood, urine and body fluid are realized.

The present invention relates to the field of tissue-derived cell identification, in particular to a method for identifying tissue-derived cells in the body fluid based on single-cell sequencing technology. In the present invention, on the basis of high-throughput single-cell RNA sequencing data of cell samples obtained from body fluids, by means of reference component analysis (RCA), expression of known tissue-related marker genes, and a tissue-derived cell prediction model constructed based on logistic regression, the specific identification of tissue-derived cells in body fluids is achieved.

The invention belongs to the technical field of flexible sensing, and particularly relates to a preparation method of an implantable flexible sensor and a bladder urine content wireless monitoring system based on the sensor and a radio frequency mechanism. Wherein the performance of the sensor is improved by utilizing a microporous structure, n-octane is added into TPU to form a porous dielectric layer through a method of different temperatures and different liquid solubility, and the second dielectric layer is added into TPU by using a core-shell structure of silver nanowires and titanium dioxide, so that the anti-interference performance of the pressure-volume sensor is remarkably improved. In addition, the overall structure of the sensor is designed into a semi-bent snake-shaped structure, and the sensor has good pressure-volume performance, sensitivity, restorability and anti-interference performance. The elastic silicone rubber is used for packaging, so that the biocompatibility and practicability of the material are improved, and unstable factors such as body fluid invasion are eliminated. Meanwhile, a wireless sensing system based on a radio frequency mechanism is designed and manufactured, the urine content of the bladder can be wirelessly known from the outside, and related work such as medical care can be helped.

Disclosed are automated urinary output (“UO”)-measuring systems and methods. An automated UO-measuring system can include a container configured to collect a fluid such as urine. The container can include a console, one or more ultrasonic sensors coupled to the console for determining a fluid level within the container, one or more accelerometers coupled to the console for determining a near-zero acceleration state of the container for the determining of the fluid level within the container, and a valve configured to pass fluid therethrough by way of a fluid line coupled to the valve. The automated UO-measuring system can also include a container holder. The container holder can have a pocket for holding the container and a sleeve for securing the container to a user. A method of the automated UO-measuring system can include a method of using the automated UO-measuring system to collect and measure urine output of the user.

A system for the hypothermic transport of biological samples, such as tissues, organs, or body fluids. The system includes a self-purging preservation apparatus to suspend a sample in preservation fluid and perfuse a tissue with preservation fluid. The self-purging preservation apparatus is placed in an insulated transport container having a cooling medium. When assembled, the system allows for transport of biological samples for extended periods of time at a stable temperature.

The invention provides a traditional Chinese medicine symptom association prediction method based on similarity and a graph neural network. According to the method, multi-dimensional characteristics such as taste, nature, channel tropism and rising and falling of traditional Chinese medicines and characteristics such as exogenous causes, endogenous causes, qi, blood, body fluid and viscera of symptoms of the traditional Chinese medicines are extracted from a traditional Chinese medicine knowledge base, and a quantitative expression system is constructed. And constructing a three-dimensional similarity vector matrix of the traditional Chinese medicine and the symptoms by calculating the similarity of each first-level feature, and fusing the three-dimensional similarity vector matrix with the traditional Chinese medicine-symptom incidence matrix to form a GNN input graph structure. In the GNN, feature interaction between traditional Chinese medicine and symptom nodes is realized by using a message passing mechanism, node embedding is updated through three times of iteration, and a correlation score matrix is output in combination with a double-line decoder. And aiming at the problem of data imbalance, a weighted cross entropy loss function optimization model is adopted, a correlation threshold is automatically generated, and accurate prediction is realized. The method effectively excavates deep correlation between traditional Chinese medicine and symptoms, and provides a data-driven prediction tool for modern research of traditional Chinese medicine.

The invention provides an intermittent detection method and device for body fluid parameters and a related system.The method is applied to a body fluid parameter detection system, the system comprises an infusion tube, a detection module, an extraction and injection device, a liquid path switch and a flushing device.The method comprises the steps that the liquid path switch is controlled to execute a closing action, and the liquid path switch is controlled to close the infusion tube; controlling the extraction and injection device to extract a preset first volume of target body fluid from a preformed hole of a target user into the infusion tube, controlling the detection module to detect parameters of the target body fluid when the target body fluid in the infusion tube is detected to pass through the detection module, obtaining the parameters of the target body fluid, controlling the liquid path switch to execute an opening action, and controlling the liquid path switch to execute a closing action; and controlling the flushing device to inject a preset second volume of functional liquid into the infusion tube, and controlling the extraction and injection device to enable the target body fluid to flow back to the target user when the functional liquid in the infusion tube is detected to pass through the detection module. When blood gas parameter detection is carried out, blood waste and detection cost are reduced.

An apparatus includes a housing, a flow control mechanism, and an actuator. At least a portion of the flow control mechanism is movably disposed within the housing. The apparatus further includes an inlet port and an outlet port, and defines a fluid reservoir. The outlet port is fluidically coupled to a second fluid reservoir and is fluidically isolated from the first fluid reservoir. The actuator is configured to move the flow control mechanism between a first configuration, in which the inlet port is placed in fluid communication with the fluid reservoir such that the fluid reservoir receives a first flow of bodily-fluid, and a second configuration, in which the inlet port is placed in fluid communication with the outlet port.

The present embodiments relate generally to a soft system for producing a giant magnetoelastic effect. In some embodiments, the soft system is composed of platinum-catalyzed silicone polymer matrix and neodymium-iron-boron nanomagnets. The soft system shows up to four times more enhancement of the magnetomechanical coupling factor (T / Pa) than traditional rigid counterparts owing to a distinct physical mechanism. In embodiments, the giant magnetoelastic effect is coupled with magnetic induction to implement a soft magnetoelastic generator (MEG) as an approach to biomechanical energy conversion, a technology that was heretofore conventionally challenged by low current, high internal impedance, and low water / humidity resistance for decent operation stability. This new method of biomechanical-to-electrical conversion is intrinsically waterproof since the magnetic fields are able to penetrate water with negligible intensity loss. Thus, it was demonstrated to work stably on wet skin or in body fluids without any encapsulation, opening up alternative avenues for practical human-body centered energy, sensing, and therapeutic applications.

The present invention relates to a method for correcting a biometric value of a user in a biometric information measurement system and, more specifically, to a biometric value correction method, which determines, from the difference between a blood biometric value and a body fluid biometric value, whether a biometric value is stabilized when a correction factor is calculated using a reference biometric value, so as not to use the correction factor calculated from the reference biometric value if the biometric value is unstable and to use a revised correction factor obtained by weighting the correction factor, and thus can accurately determine a corrected biometric value of a user from a biometric value measured by a sensor.

Proposed is an automated formulation design system and method thereof for determining tablet and capsulation formulations providing a targeted delivery of active pharmaceutical ingredients to a patient with a desired release profile in defined body fluids based on experimental measurements of material attributes for simulated dissolution, disintegration, diffusion, compression, deformation and / or other properties of individual materials or combinations and mixtures thereof. The formulation at least comprises required quantities of the required active pharmaceutical ingredients and excipients providing targeted dissolution and / or solubility factors and / or targeted protection of the active pharmaceutical ingredients during their transport and distribution into interstitial and intracellular fluids.

Doubly labeled water with enhanced protocol. One embodiment is a method including providing, to a user, a doubly labeled water (DLW) dose for the user to ingest, the DLW dose including deuterium and oxygen-18, wherein an amount of the deuterium is less than 0.12 grams per kilogram (g / kg) of body water of the user, and wherein an amount of the oxygen-18 is less than 0.18 g / kg of body water of the user. The method also includes receiving, from the user, a non-cooled shipment of urine samples collected in connection with ingestion of the DLW dose, wherein the urine samples remain uncooled after collection and during transit for a period of up to 24 days. The method further includes processing the urine samples with a liquid water isotope analyzer to determine one or more metabolic parameters of the user.

The invention discloses a self-breaking outer drainage tube, and relates to the technical field of medical instruments, the self-breaking outer drainage tube comprises a tube body, and the tube body comprises a drainage part, a breaking part, a leading-out part and a puncture part; the drainage part and the fracture part are both made of degradable materials; the hole wall thickness of the circulation hole at the fracture part is smaller than the hole wall thickness of the circulation hole at the drainage part; during surgical operation, the degradable inner drainage part is placed in the pancreatic duct, the fracture part crosses the anastomotic stoma by 7-8 cm and crosses the biliary-intestinal anastomotic stoma, and the leading-out part walks in the enteric cavity to a proper position, penetrates out of the intestinal wall and is led out of the body through the abdominal wall. Cutting the puncture part to expose the outlet of the circulation hole, and discharging the body fluid through the circulation hole; after a certain period of time after the operation, the fracture part is automatically fractured under the action of pancreatic juice, the leading-out part is pulled out, the degradable drainage part continues to be degraded in the body and maintains the drainage function, and finally the drainage part is absorbed by the body or discharged out of the body without being taken out through the operation.

Systems, devices, and methods herein may include a system for monitoring bodily fluid from a patient. In some embodiments, the system may be configured to collect bodily fluid samples from a patient periodically over time to determine a baseline bodily fluid composition. In some embodiments, the system may use spectrophotometry to determine the baseline bodily fluid composition for the patient. The system may be configured to compare a bodily fluid sample to the baseline bodily fluid composition to detect detecting changes in one or more characteristics of the bodily fluid sample (e.g., composition, absorption spectrum, etc.) from the baseline. Changes in the bodily fluid sample characteristics may be used to predict and / or detect abnormalities or infection for individualized diagnosis.

A method comprising obtaining a bodily fluid from a subject; contacting the bodily fluid with an adsorbent material comprising a synthetic carbon particle (SCP) to produce a first filtrate having a level of disease mediators (y); contacting the first filtrate with an adsorbent material comprising the SCP and an anion exchange resin where the ratio of SCP to anion exchange resin is in a range from about 0.1:100 to 100:0.1 to produce a second filtrate; contacting the second filtrate with an adsorbent material comprising the SCP and a cation exchange resin where the ratio of SCP to cation exchange resin is in a range from about 0.1:100 to 100:0.1 to produce a third filtrate.

The invention relates to absorbable adhesive styptic powder and a preparation method thereof, and the absorbable adhesive styptic powder is characterized in that the absorbable adhesive styptic powder is formed by cross-linking aldehyde polysaccharide and a polyamino compound through Schiff base reaction, the raw materials are selected from at least one of glucan, sodium carboxymethyl cellulose, sodium hyaluronate, chitosan and carboxymethyl starch; the polyamino compound is selected from at least one of polylysine, polypeptide, bovine serum albumin and polyamine; the styptic powder is porous particles with the particle size of 10-1000 meshes, is cured into gel within 10 seconds after being in contact with body fluid, and is completely degraded within 15-60 days. According to the scheme, the styptic powder has the advantages of rapid wet adhesion, controllable degradation and excellent processability, and is an urgent clinical demand.

The invention relates to the technical field of animal body component detection, and provides a portable animal body component analyzer, which comprises a data acquisition module, a data processing module, an analysis module, a data processing module, an analysis module and an analysis module, wherein the data acquisition module is responsible for acquiring multi-frequency bioelectrical impedance data and near infrared spectrum data of domesticated pets; the data processing module is used for carrying out noise filtering, dynamic baseline correction and normalization processing on the collected original data; the algorithm analysis module uses a variety inference and dynamic correction method to correct data errors, extracts body fat distribution, tissue metabolism and body fluid distribution characteristics through a multi-modal data fusion method, and calculates growth and development health scores through an integrated learning supervision model; the database management module stores individual information, appearance characteristics, measurement data and analysis results, and supports data query and backtracking; the user interface is used for inputting animal information and hair states and displaying analysis results, variety similarity, body composition change trends and health scores.

The invention discloses bi-crosslinking self-reinforced hydrogel based on endogenous glucose in-situ initiation as well as a preparation method and application of the bi-crosslinking self-reinforced hydrogel, and relates to the technical field of biomedical materials. The double-crosslinking self-enhanced hydrogel is prepared from the following components in concentration: 1 to 3 weight percent of hyaluronic acid-tyramine, 0.8 to 1.2 weight percent of sodium alginate, 1 to 100 mmol / L of calcium carbonate, 0.0001 to 10 U / mL of horse radish peroxidase, 20 to 40 U / mL of glucose oxidase and the balance of ultrapure water. The invention also discloses an application of the double-crosslinking self-reinforced hydrogel in preparation of a filling and repairing product for soft tissue defects. The hydrogel disclosed by the invention can be filled in a tissue defect part in an injection manner, glucose in body fluid is utilized to initiate crosslinking in situ to form the hydrogel with excellent mechanical properties and long-term stability, and meanwhile, the hydrogel is good in biocompatibility and relatively high in application value.

The invention discloses a clinical body fluid monitoring and early-warning device and a monitoring and early-warning method thereof, and relates to the field of medical instruments, the clinical body fluid monitoring and early-warning device comprises a shell, a shunting mechanism is mounted in the shell, and the shunting mechanism is connected with a monitoring mechanism. According to the clinical body fluid monitoring and early warning device and the monitoring and early warning method thereof, the gravity monitoring mechanism is adopted, the bleeding amount of a patient can be monitored in real time, a buzzer and a warning lamp are used in cooperation, medical staff can be warned when the bleeding amount of the patient reaches the dangerous blood loss amount, and the specific content is that the medical staff can conveniently monitor the bleeding amount of the patient. Drainage blood can be fed into a liquid storage bag to be stored under the action of a flow dividing pipe, a threaded connector, a connecting pipe and a connector, the weight of the blood stored in the liquid storage bag can be detected in real time and fed back to a controller under the action of a top plate, a first spring and a weighing sensor, and when the weight of the blood reaches a preset value, the controller is started. The controller controls the buzzer and the warning lamp to be started, and the warning effect on medical staff is achieved.

An example drainage port assembly includes a collar and a connector, The connector includes an engagement portion that is attached to or integrally formed with the collar and the conduit attachment portion that is distinct from the engagement portion. The engagement portion is configured to allow the conduit attachment portion to move relative to the collar. The collar and the connector define a collar passageway extending through the collar and a connector passageway extending through the connector, respectively. In some embodiments, the movement of the conduit attachment portion relative to the collar switches the drainage port assembly between a first state and a second state, wherein the drainage port assembly permits flow of bodily fluids therethrough when in the first state (e.g., through the collar passageway and the connector passageway) and restricts the flow of the bodily fluids therethrough w hen in the second state.