102 results about "Hypothermia" patented technology

A method for transporting a biological sample at hypothermic temperatures. The container can be cooled using phase change material and pump fluid through the sample. The fluid can pump through the system at a rate independent of the parameters of the biological sample. A valve can control the rate of flow of the fluid into the biological sample.

A system for the hypothermic transport of biological samples, such as tissues, organs, or body fluids. The system includes a self-purging preservation apparatus to suspend a sample in preservation fluid and perfuse a tissue with preservation fluid. The self-purging preservation apparatus is placed in an insulated transport container having a cooling medium. When assembled, the system allows for transport of biological samples for extended periods of time at a stable temperature.

A hypothermia insulative cap is provided enhanced with a GPS-enabled LED strip for emergencies, constructed from dual-layer nylon and neoprene with advanced seam technologies for durability and comfort. It features a unique technology chassis for waterproofing essential electronics, a battery-activated GPS and LED for increased visibility, and a protective brow visor for comfort and protection. This cap is designed to maintain body temperature during waterborne rescues, offering increased visibility to rescuers and compatibility with conventional life vests, without impeding the function of either device.

The invention belongs to the technical field of low-temperature biology, and discloses deep hypothermia biological sample storing and taking equipment which comprises a low-temperature storage cabinet, a plurality of storage cavities are formed in the low-temperature storage cabinet, the storage cavities are arranged in the thickness direction of the low-temperature storage cabinet and extend to the front face of the low-temperature storage cabinet, and first door bodies are rotationally installed on the side walls of the storage cavities and can seal the storage cavities; sample boxes are slidably installed in the storage cavities in the thickness direction of the low-temperature storage cabinet, the sample boxes are used for containing samples, and a cooling module of a refrigerating system is installed on the back face of the low-temperature storage cabinet and used for stably and safely providing cooling capacity for the multiple storage cavities; the management center is used for controlling the first door body to rotate, controlling the sample box to be pushed out or withdrawn and driving the mechanical arm to take out a target sample in the low-temperature storage cabinet or place the sample in the target sample box by adjusting the position of the mechanical arm, so that automatic and efficient sample storage and taking are achieved.

The invention discloses an organ mechanical perfusion system which comprises a liquid storage container used for storing perfusion liquid; the perfusion pump is used for extracting the perfusion liquid in the liquid storage container and perfusing the organ through the perfusion pipeline; the oxygenator is used for oxygenating perfusate and organs; the temperature control module is used for maintaining the temperature of the organ and the perfusate in a set range; the main control module is used for controlling the perfusion pump and the temperature control module according to the perfusion parameters, controlling the temperature control module to place the organ in a low-temperature state in a first time period, and controlling the perfusion pump to stop perfusion action or perform slow perfusion action in the low-temperature state so as to enter a maintenance stage; and in the second time period, the temperature control module is controlled to place the organ in a normal temperature or sub-normal temperature state, and the perfusion pump is controlled to execute normal perfusion action in the normal temperature or sub-normal temperature state, so that a normal perfusion stage is started. Wherein the maintenance stage of the first time period and the normal perfusion stage of the second time period can be alternately carried out.

A system for the hypothermic transport of biological samples, such as tissues, organs, or body fluids. The system includes a self-purging preservation apparatus to suspend a sample in preservation fluid and perfuse a tissue with preservation fluid. The self-purging preservation apparatus is placed in an insulated transport container having a cooling medium. When assembled, the system allows for transport of biological samples for extended periods of time at a stable temperature.

This invention provides a rapid rewarming and circulatory support system for frostbite and hypothermia in high-altitude environments, relating to the field of treatment device technology. It includes: a first temperature acquisition module for acquiring and preprocessing the current first ambient temperature, the first frostbitten skin surface temperature, and a first skin surface image; a control module connected to the first temperature acquisition module for analyzing the preprocessed first ambient temperature, the first frostbitten skin surface temperature, and the first skin surface image to determine the corresponding first target temperature and a first target warming rate; and a temperature regulation module connected to the control module for gradually warming the skin to the optimal preset temperature according to the warming rate. This invention achieves dynamic temperature control, continuous protection, and intelligent decision-making for frostbite and hypothermia in high-altitude environments.

The utility model provides a portable intelligent temperature-control low-body-temperature emergency rewarming cap which is suitable for emergency rewarming treatment of low-body-temperature wounded persons in an outdoor extremely low-temperature environment. The rewarming cap comprises a cap body, a carotid artery rewarming device and an intelligent control system, the carotid artery rewarming device is internally provided with a graphene heating piece and a heat conduction silica gel pad, and the carotid artery is accurately heated to achieve the in-vivo rewarming effect; the intelligent control system integrates a temperature sensor and a heart rate sensor, monitors the heating temperature and the heart rate in real time, and dynamically adjusts the heating power and feeds back the vital signs of the wounded through a microprocessor; a heating patch storage box is arranged on the lower portion of the intelligent control system, a folding front chest heating patch capable of being unfolded on the chest is arranged in the heating patch storage box, the core body temperature is increased by rewarming the front chest cardiopulmonary area through the body surface, and the problems that an existing low-body-temperature rewarming device is low in efficiency of the body surface rewarming mode and inconvenient to carry are solved.

The utility model belongs to the technical field of medical instruments, and discloses a multifunctional out-call medical kit which comprises a medical kit body, a control panel, a controller, a storage and a storage battery. The medicine box body comprises a refrigeration medicine storage box and a normal-temperature medicine storage box, medicine storage cavities are formed in the refrigeration medicine storage box and the normal-temperature medicine storage box, medicine storage drawers are arranged in the medicine storage cavities in a sliding mode, and the medicine storage drawers are connected with a rear panel of the refrigeration medicine storage box or the normal-temperature medicine storage box through a driving mechanism. A temperature sensor and a semiconductor chilling plate are arranged in a medicine storage drawer of the refrigeration medicine storage box; real-time types, quantity and daily common disease prescriptions of medicines in the medicine chest main body are stored in the memory; the control panel is provided with a touch display screen and a first medicine code scanner used for scanning identification codes on the surfaces of the medicine boxes. The medical kit is suitable for medical staff to go out to see a doctor, part of medicine can be stored in a specified low-temperature environment when the medical staff go out, and the medicine taking condition of a patient can be conveniently traced.

The invention discloses a preparation method of an intestinal canal filling temperature-sensitive gel injection for gastrointestinal anastomosis guided by an ultrasonic endoscope, and belongs to the technical field of regenerative medicine. According to the specific method, poloxamer, chitosan, polycarbophil, polyvinylpyrrolidone, iohexol and methylene blue are utilized to construct the novel intestinal canal filling temperature-sensitive gel injection. The injection can be injected into the anastomotic intestinal segment of the small intestine by using a conventional nasobiliary drainage tube which is clinically used at present, and the injection becomes viscous immediately under the action of the pH value of the small intestine after injection, so that the injection is inhibited from spreading all around. Meanwhile, the injection is quickly converted into high-strength hydrogel under the action of body temperature, and the hydrogel is adhered to small intestine mucosa to inhibit gel sliding. Therefore, the injection can form a section of gel on a target small intestine section, local immobilization filling and supporting of the target small intestine section are achieved, development can be achieved, the operation difficulty of intestinal tube puncture and stent placement in gastrointestinal anastomosis guided by an ultrasonic endoscope can be greatly reduced, the operation efficiency and the success rate are improved, and the operation cost is reduced. The dosage is less than that of normal saline which is conventionally used clinically, and the effect is better. Moreover, the gel temperature can be reduced by injecting low-temperature normal saline after the operation, so that the gel is thoroughly dissolved into a solution and discharged out of the body, and the phenomenon that the gel remains in the intestinal canal after the operation to cause obstruction is avoided. Therefore, the novel intestinal canal filling temperature-sensitive gel injection has very important clinical practical application value for gastrointestinal anastomosis guided by an ultrasonic endoscope.

The utility model discloses a multi-point wrapping type medical fixing band capable of being opened and closed for children. The multi-point wrapping type medical fixing band comprises a main band body and a plurality of bandage bodies. A window is formed in the middle of the front end of the main belt body. The chest and the knees of a child are wrapped by the main belt body, and the bandage bodies are fixedly connected with the edge of an operating bed in a matched mode, so that the child can be well fixed in the whole process in the operation, adverse events such as falling down and falling off the bed are effectively prevented, the bandage body corresponding to the puncture part can be independently opened during general anesthesia venipuncture of the child, and the operation is convenient. Meanwhile, the window is formed, and a transparent adhesive film capable of opening or closing the window is arranged in a matched mode, so that a doctor can conveniently observe a child in time during an operation, warm keeping of a patient is achieved, and hypothermia of the patient during the operation is prevented; the main band body is composed of the cotton cloth base layer, the first antibacterial non-woven fabric and the second antibacterial non-woven fabric, and a better sterile environment is provided for the operation process.

The invention relates to the field of organ transplantation in biomedical technology, and particularly discloses normal-temperature perfusion protection liquid for thoracoscopic surgery training as well as a preparation method and application of the normal-temperature perfusion protection liquid. The components of the perfusion protection liquid mainly cover sodium chloride, carbohydrates, adenosine and dexamethasone. The perfusion protection liquid has the advantages that on one hand, the components of the protection liquid are simple, complex components of a traditional perfusion protection liquid are abandoned, and the raw material obtaining and economic cost is greatly reduced; and on the other hand, the perfusion protection liquid gets rid of the limitation of low-temperature storage and can be stably stored in a normal-temperature environment. Compared with the prior art, the perfusion protection liquid provided by the invention not only has simple components, but also breaks the constraint of cold chain transportation and low-temperature storage, solves the problems of complex components and harsh storage conditions of the existing protection liquid, provides a more convenient and efficient solution for thoracoscopic surgery training and even wider medical practice, and has broad application prospects. The method has a wide application prospect and an extremely high practical value.

A tissue storage solution includes hypothermic storage compositions and methods. The hypothermic storage composition includes media containing Dulbecco's modified Eagle's medium (DMEM) and albumin. A method of hypothermically storing tissue includes storing such tissue in a storage medium including DMEM and albumin. A method for wound or defect treatment includes applying tissue, stored in a hypothermic storage medium containing DMEM and albumin, to the site of such wound or defect.

The invention belongs to the technical field of medical equipment, and particularly relates to a movable cooling bed which comprises a movable sickbed. The top surface of the movable sickbed is fixedly connected with a water bed; a water tank for a patient to lie on the back is formed in the top surface of the water bed; the top surface of a bottom bracket of the movable sickbed is fixedly connected with a micro cooling-water machine; the water inlet end and the water outlet end of the micro cooling-water machine are respectively communicated with the two ends of the water tank through pipelines; clean water in the water tank is pumped into the micro cooling-water machine by the micro cooling-water machine for cooling, and low-temperature cold water is conveyed into the water tank through a pipeline. Cold water in the water tank exchanges heat with the patient to absorb body heat, so that the core body temperature of the patient is reduced; therefore, the core body temperature of the patient is effectively reduced, the patient can be continuously kept in a low-temperature state, and an effective, stable and safe low-temperature environment is provided for treatment and transfer of the patient; therefore, the effectiveness of treating and curing the patient is greatly improved, and the injury to the patient is reduced.

The invention discloses an inflatable heating shoulder pad capable of preventing hypothermia in an operation, and belongs to the field of medical instruments. Comprising a folding mounting mechanism, and shoulder pad mechanisms are arranged in front of and behind the folding mounting mechanism; the folding mounting mechanism comprises two connecting pieces, two steering heads are rotationally connected between the two connecting pieces through rotating shafts, and two extension rods are fixedly connected to the left sides of the steering heads; the problem of compression injury of an existing shoulder rest is effectively solved, the comfort level of a patient in an operation is improved, flexible supporting of the shoulders of the patient is achieved through the inflatable air bag, traditional hard and semi-hard shoulder rests are replaced, shoulder blood circulation blocking caused by long-term compression can be avoided, uncomfortable symptoms such as shoulder ache, stiffness and numbness after the patient is awakened are reduced, and the patient can be prevented from being injured. Meanwhile, skin injury risks such as skin redness, damage and pressure sores caused by local compression are reduced, postoperative pain of a patient is relieved, and the recovery period is shortened.

The operating table with the temperature control function comprises a bed frame, the bed frame at least comprises a head pillow section, a back pillow section and a leg pillow section, each area is provided with a first temperature sensor for monitoring the temperature and a temperature control structure for adjusting the temperature, and each temperature control structure comprises a heating mechanism and a cooling mechanism. The operating table further comprises a control system capable of receiving signals of the first temperature sensors so as to control the corresponding temperature control structures to adjust the temperature. Accurate temperature control can be carried out according to different surgical sites, for example, different surgical requirements that neurosurgery needs head low temperature, abdominal surgery needs trunk constant temperature and the like. Compared with a traditional single global temperature control scheme, the local overheating or supercooling risk is effectively avoided, and the intraoperative complications and the postoperative infection rate are remarkably reduced.

A folded dipole patch antenna for use in a hyperthermia applicator is described. The antenna includes a dielectric circuit board, and a folded dipole microstrip antenna. The dielectric circuit board has a top side and a bottom side. The folded dipole microstrip antenna is formed on the top side and includes two meander paths mirror each other. A pair of parallel metallic strips is located on the bottom side. A coaxial feed port is connected to the pair of parallel metallic strips. The antenna is configured to resonate in a frequency range of about 434 MHz upon application of an input signal at the coaxial feed port. The folded dipole patch antenna has a small size and does not require an impedance matching circuit. The hyperthermia applicator is configured to emit microwave energy toward a target tissue within a human body.

The invention discloses an intelligent monitoring feedback type whole body thermal therapy exercise combination suit and an intervention method, the intelligent monitoring feedback type whole body thermal therapy exercise combination suit comprises a whole body wearable suit and a controller, thermal therapy modules are arranged on the head, the neck, the chest, the abdomen, the upper limbs and the lower limbs of the whole body wearable suit and are used for performing thermal therapy on each area, and the temperature of the thermal therapy module of each area is independently controlled; a heart rate sensor is arranged on the chest of a user, blood pressure sensors are arranged at the positions of upper limb cuffs, the thermal therapy module, the blood pressure sensors and the heart rate sensor are all connected with a controller, and the controller is in wireless connection with an upper computer. The cooperative mode of'multiple short-time lower-temperature thermal therapy + low-intensity movement matched with respiratory training 'is adopted, the targeted thermal therapy scheme is automatically generated through the APP and issued for execution, manual complex operation is not needed, the response speed is high, the defect that personalized feedback is lacked in the prior art is overcome, the intervention precision is improved, and the system is suitable for popularization and application. And the system can be used in various scenes such as daily home and office, and is wide in applicable crowd coverage.

An assembly 100 to provide thermal therapy to a human auditory system includes a thermal transducer 125, a stimulus transducer 120, 135, a receiver 130, and a processing device 145. Some or all of the individual components may be carried in headwear. The thermal transducer 125 applies hypothermic temperature conditions to an area of the head near an ear. The stimulus transducer 120, 135 applies a stimulus signal, and the receiver 130 detects otoacoustic emission (OAE) responsive to the stimulus signal. The processor 145 compares the received OAE signal to a reference. Discrepancy between the OAE and reference is used in a feedback loop to control operation of the system 100.

System, devices and methods for providing a blood-free operative region for aortic arch repair procedures. Various embodiments disclose occlusion of the descending aorta, the innominate artery, the left carotid artery and the left subclavian artery while also providing sufficient perfusion distal of the occluding balloons. Various embodiments disclose performing aortic arch repair procedures while the patient's body temperature is maintained an normothermia (about 36 degrees C. to about 37.5 degrees C.). Other embodiments disclose performing aortic arch repair procedures while the patient's body temperature is maintained at slight hypothermia (about 30 degrees C. to about 34 degrees C.).

A cervical collar that facilitates therapeutic hypothermia is provided and includes a cooling device having a front portion and a back portion fixedly coupled to the front portion on one side and removably coupled to the front portion on an opposite side. A fastening device removably couples the back portion to the front portion on the opposite side. The cooling device induces hypothermia in at least a portion of a patient. A sensor is provided that measures a physical characteristic of the patient.

The invention relates to the technical field of intelligent medical control and low-temperature plasma medical application, in particular to an intelligent decision-making system for CAP treatment of nephropathy skin complications based on multi-parameter dynamic monitoring. Comprising a multi-modal physical sign acquisition module which is used for acquiring multi-dimensional physiological characterization signals of local tissues and synchronously acquiring periodic metabolism interference data containing dialysis time sequence information; the tolerance threshold inversion module is used for obtaining a local tissue oxidation-reduction tolerance threshold through inversion by using a tissue oxidation-reduction tolerance calculation model; the dynamic interference compensation module is used for generating a real-time safety boundary threshold value; the adaptive strategy generation module is used for generating candidate treatment control strategies by using a deep reinforcement learning algorithm; the risk boundary control module is used for calculating an expected oxidative stress level, if the expected oxidative stress level is larger than or equal to a real-time safety boundary threshold value, blocking or degrading operation is executed, and otherwise, a final treatment instruction is output; the therapeutic dose control precision is improved to the physiological response level, and the iatrogenic skin necrosis risk is effectively avoided.

The invention discloses a traditional Chinese medicine formula for treating cerebral infarction, three highs and hyperuricemia and a preparation method thereof. The composition comprises 48 medicinal materials such as radix astragali and radix salviae miltiorrhizae, and combined treatment of multiple diseases is achieved through the synergistic effect of tonifying qi, activating blood, dredging collaterals and descending turbidity. The preparation method adopts ceramic membrane filtration and low-temperature spray drying processes, and the retention rate of active ingredients is increased by 30%. An embodiment verifies that the traditional Chinese medicine composition can be prepared into tablets, granules and other dosage forms, can synchronously improve neurological functions and metabolic indexes through clinical verification, and has high efficiency and safety.

This invention discloses the application of a UBC9 overexpression reagent in the preparation of drugs for preventing hypothermia caused by acute cold exposure, belonging to the field of biomedical technology. In vitro and in vivo experiments confirmed that acute cold exposure can induce a significant upregulation of UBC9 expression in skeletal muscle. Further, a skeletal muscle-specific UBC9 overexpression mouse model was constructed, revealing that UBC9 overexpression significantly enhances the core body temperature maintenance capacity of mice under acute cold exposure, upregulates the expression of the key thermogenic protein UCP3 and mitochondrial functional proteins TOMM20 and COX4, alleviates mitochondrial structural damage, and reduces mitochondrial oxidative stress levels. This invention reveals for the first time that UBC9 is a key target for the regulation of skeletal muscle thermogenicity under acute cold exposure. Enhancing UBC9 expression can effectively prevent or improve skeletal muscle thermogenic dysfunction caused by cold environments, providing a novel intervention strategy for developing drugs to prevent and treat cold injury.

The invention discloses temperature control type dragon's blood cataplasm as well as a preparation method and application thereof, and belongs to the technical field of medical instruments and traditional Chinese medicine external preparations. The cataplasm is of a layered composite structure and comprises a backing layer, a temperature control heating layer, a heat insulation temperature control layer, a cataplasm matrix layer containing a dragon's blood extract and an anti-sticking layer. Through cooperation of the heating layer material and the breathable temperature control material, the application temperature can be accurately controlled to be 40-50 DEG C and lasts for 2-4 hours, controllable low-temperature thermal therapy and the pharmacological action of the dragon's blood are organically combined, and synergistic interaction of thermal therapy and medical therapy is achieved. The product can remarkably promote hematoma absorption and relieve swelling and pain, is safe and convenient to use, is particularly suitable for treatment of subacute stages such as post-trauma subcutaneous hematoma, post-arterial paracentesis subcutaneous hematoma and soft tissue injury, and has a wide clinical application prospect.

The present invention relates to a pharmaceutical use, of a compound of formula I or a salt thereof, for improving mortality, neurological impairment, and / or daily activity in patients with resuscitated cardiac arrest receiving target temperature management (TTM) for maintaining a temperature between about 32°C and about 36°C, patients with ischemic or hemorrhagic stroke receiving TTM, patients with traumatic brain or spinal cord injury receiving TTM, or patients with hypoxic-ischemic encephalopathy receiving TTM.

The application belongs to the technical field of medicine, and discloses application of oxeladin in preparation of a medicine for preventing or treating perioperative hypothermia. The dose of the medicine ranges from 1 to 3 mg. The medicine is applied to perioperative hypothermia caused by general anesthesia. The general anesthesia includes sevoflurane and esketamine. The medicine further comprises a pharmaceutically acceptable carrier and / or excipient. It is found in the previous application that the incidence of hypothermia and chills after general anesthesia is significantly reduced in the oxeladin administration group compared with the blank control group, and the further verification is carried out through animal experiments. The achievement of the application provides an effective prevention and treatment scheme for improving perioperative hypothermia and chills in clinic.

The utility model relates to the field of medical equipment, and discloses a visceral organ heat preservation device which comprises a bag body, the bag body comprises a plurality of mutually connected bags, the inner layer of each bag is provided with a leakage-proof layer, the outer layer of each bag is provided with a protective layer, a flexible folding part is arranged between every two adjacent bags, and a water inlet channel is arranged on each flexible folding part. One bag is provided with a water inlet pipe, the water inlet pipe is communicated with the interior of the bag, and the water inlet pipe is provided with a water inlet cover. The leakproof layer is arranged on the inner layer of the bag, and the protective layer is arranged on the outer layer of the bag, so that the bag is resistant to high temperature and not prone to damage; the flexible folding parts are arranged between the adjacent bags, so that the bags on the bag body can be folded into different sizes along the flexible folding parts to adapt to visceral organs of different parts of a patient, the visceral organs of the patient can be effectively prevented from losing temperature, and the use effect is better.

The present application relates to the technical field of medical devices, in particular to a kind of external device for treating male erectile dysfunction, including outer tube, and the negative pressure pump and internal inner tube of the internal inside being arranged at the front end of outer tube,It also includes ball hinge seat, movably connected at the rear end of outer tube, and there is silica gel sealing ring at the opening of its rear end;Control center, installed at the front end inside outer tube, and installed at the output end of negative pressure pump, control center is connected with temperature control sensing device, temperature control sensing device is installed on the I-shaped connecting seat at the rear end of inner tube, solve the single negative pressure control mode of existing device, manually cannot be accurate control pressure and cause tissue damage or affect erection effect, the pressure program of automatic version is fixed, complex structure, poor portability, and cannot be adapted to the angle change after penis erection, easily cause compression pain, air leakage pressure loss;Lack of auxiliary physical stimulation, limited efficacy;In addition, local hypothermia under negative pressure causes body discomfort, also can contract blood vessels, hinder blood perfusion and erection maintenance problem.

The invention discloses a diving safety early warning method and system based on multi-modal data fusion, and the method comprises the steps: inputting first environment data, physiological data and motion posture data into a first LSTM model for risk assessment if the motion state of a diver is diving or static, and obtaining a temperature loss risk index; if the motion state of the diver is rising, inputting the first environment data, the second environment data, the physiological data and the motion posture data into a second LSTM model for risk assessment to obtain a temperature loss risk index and a pressure reduction risk index; when the temperature loss risk index exceeds a first threshold value or the pressure reduction risk index exceeds a second threshold value, a safety early warning signal is sent out, and a safety return path is generated through an algorithm and a flexible action-evaluation algorithm. Therefore, by implementing the method and the device, differentiated risks can be dynamically assessed in combination with different multi-modal data for different diving stages, and a safe return path is dynamically generated based on a risk assessment result.