114 results about "Mr imaging" patented technology

The invention discloses a renal clear cell carcinoma prognosis prediction method based on multi-mode MRI (Magnetic Resonance Imaging) image and digital pathological omics fusion. The method comprises the following steps: S1, collecting a training data set based on an MR image and a pathological image; s2, feature extraction of MR radiomics; s3, deep learning feature extraction of the pathological image; s4, an MR-pathological feature fusion module; and S5, deploying the network. According to the method, depth features with prognosis information are obtained from two scales of pre-treatment images and post-operation pathology, effective features are extracted by adopting image omics and a convolutional neural network mode according to data characteristics of MR images and pathology images, and depth fusion of the two types of features is completed in a hidden space through a multi-task guiding mode, so that the accuracy of the MR image and the pathology image is improved. A precise prognosis model with multi-scale information is provided, and the method has a relatively strong clinical application prospect and is of great significance for realizing precise immunotherapy and improving prognosis of a patient.

The invention relates to a method of MR imaging of an object positioned in the examination volume of an MR system (1). It is an object of the invention to provide a deep learning-based denoising approach that overcomes the Rician bias problem. As a solution, the invention proposes a method comprising the following steps: a) subjecting the object to an imaging sequence comprising RF pulses and switched magnetic field gradients, whereby MR signals are generated, b) acquiring the MR signals, c) reconstructing a complex-valued MR image from the acquired MR signals, d) denoising the MR image using a deep learning algorithm that operates on the real and the imaginary parts of the MR image, and c) computing a magnitude MR image from the denoised complex-valued MR image. According to an aspect of the invention, the deep learning algorithm uses a set of denoising models that are trained using different loss functions. In this way, a trade-off between noise removal and preservation of small image details can be controlled. Moreover, the invention relates to an MR system (1) and to a computer program for an MR system (1).

A computer-implemented method for transforming magnetic resonance (MR) imaging across multiple vendors is provided. The method comprises: obtaining a training dataset, wherein the training dataset comprises a paired dataset and an un-paired dataset, and wherein the training dataset comprises image data acquired using two or more MR imaging devices; training a deep network model using the training dataset; obtaining an input MR image; and transforming the input MR image to a target image style using the deep network model.

A device (18) configured to filter magnetic resonance (MR) signals includes, at least one electronic processor (24) programmed to: receive at least one MR signal (26) excited in a subject disposed in an MR imaging device (10); transform the at least one MR signal with a coherence function representing the at least one MR signal as an instantaneous frequency spectrum as a function of time: apply spectral filtering to the transformed at least one MR signal; and reconstruct at least one medical image from the filtered at least one MR signal.

A method and a system include obtaining calibration scan data or low resolution images of a subject acquired with a magnetic resonance (MR) scanner of an MR imaging system. The method and the system also include inputting the calibration data or the low resolution images into a trained deep learning-based multi-mask segmentation network. The method and the system further include outputting labeled mask images for different anatomical stations, wherein a respective mask of a respective labeled mask image highlights an anatomical landmark of interest in each respective anatomical station of the different anatomical stations. The method and the system even further include determining an extent of a respective anatomical landmark of interest in each respective anatomical station of the different anatomical stations for a respective localizer scan for each respective anatomical station based at least on a respective label mask image for each respective anatomical station.

The present disclosure describes a device, system, and methods for low-field magnetic resonance (MR) imaging. For example, a method for low-field MR imaging can include projecting a primary static magnetic field in a field of view, projecting a secondary static magnetic field to pre-polarize a first fluid moving toward the field of view, and acquiring a first image of the first fluid in the field of view based on a first RF pulse sequence. The method can further include projecting a tertiary static magnetic field to pre-polarize a second fluid moving toward the field of view and acquiring a second image of the second fluid in the field of view based on a second RF pulse sequence. The first image can be subtracted from the second image to generate a flow image of an object of interest positioned in the field of view.

The present invention relates to a method for MR imaging of an object (10) placed in an examination volume of an MR device (1). One object of the present invention is to achieve high-quality diffusion-weighted imaging (DWI) without distortion while minimizing artifacts caused by motion. The method of the present invention comprises the following steps: subjecting the object (10) to a dual-echo steady-state imaging sequence, generating a free induction decay signal (FID) and an echo signal (ECHO) in each interval between two consecutive RF pulses, wherein a pair of diffusion gradient waveforms (G) with equal phase integrals and opposite polarities are applied in the interval between the FID signal and the echo signal. DIF ); acquiring the FID signal and the echo signal in several repetitions of an imaging sequence with varying phase encoding; and reconstructing a diffusion-weighted MR image based on the acquired FID signal and echo signal. The present invention also relates to an MR device for performing the method and a computer program to be run on the MR device.

The invention belongs to the technical fields of medical chemistry, new materials and nanotechnology, and relates to a novel diagnosis and treatment agent in the field of interdisciplinary, in particular to a preparation method of a reduction response activation < 19 > F magnetic resonance signal amplification self-degradation nanometer diagnosis and treatment micelle. Poly (benzyl carbamate) is obtained through condensation polymerization as a basic structure, then chemical modification is performed to obtain a self-degradable fluorine-containing amphiphilic block polymer, hydrophobic drug chlorin (Ce6) is loaded through self-assembly, the self-degradable fluorine-containing amphiphilic block polymer has the characteristic of responding to degradation of glutathione (GSH) at a tumor site, and on the basis of maintaining self-degradation of a hydrophobic chain segment of the nano-micelle, the self-degradable fluorine-containing amphiphilic block polymer can be used for preparing the self-degradable fluorine-containing amphiphilic block polymer. The nano-micelle loaded with Ce6 has the advantages that the nano-micelle loaded with Ce6 is used as a carrier, the characteristic of efficient 19F MR imaging is additionally endowed, under laser irradiation, the nano-micelle loaded with Ce6 can enhance a new scheme of breast cancer photodynamic therapy, the effects of responding to tumor microenvironment self-degradation drug release and 19F MRI signal amplification are achieved, and therefore diagnosis and treatment integration of breast cancer is achieved.

A gradient coil unit surrounding a cylindrical patient receiving region and including a hollow cylindrical primary coil and a hollow cylindrical secondary coil surrounding the primary coil and the patient receiving region in a coaxial manner, having a first longitudinal end in a longitudinal direction, which is designed to receive an examination object, and a second longitudinal end lying opposite the first longitudinal end in the longitudinal direction, the primary coil having a first length in the longitudinal direction delimited by a first longitudinal position facing the first longitudinal end, and a second longitudinal position, the secondary coil having a second length delimited by a third longitudinal position facing the first longitudinal end, and a fourth longitudinal position, wherein the first length is shorter than the second length and the first longitudinal position has a greater spacing with respect to the first longitudinal end than the third longitudinal position.

The invention relates to a method of MR imaging of an object (10) positioned in an examination volume of a MR device (1). It is an object of the invention to enable efficient spiral MR imaging without blurring artefacts, even in situations of strong B0 inhomogeneity. The method of the invention comprises the following steps: —subjecting the object (10) to an imaging sequence comprising at least one RF excitation pulse and modulated magnetic field gradients, —acquiring MR signals along two or more planar spiral k-space trajectories (31, 32, 33), wherein the radial k-space speed, i.e. the rate of variation of the radial distance from the spiral origin is essentially constant along each planar spiral k-space trajectory, and wherein the two or more k-space trajectories (31, 32, 33) are offset in-plane from each other, and—reconstructing an MR image from the acquired MR signals. Moreover, the invention relates to a MR device (1) and to a computer program for a MR device (1).

Examples of the presently disclosed technology provide new systems and methods for real-time temperature propagation and tissue damage visualization during laser interstitial thermal therapy (LITT) procedures that do not rely on real-time MR imaging. Accordingly, examples enable performance of LITT procedures in regular operating rooms lacking MR-equipment-thereby reducing costs and improving availability for LITT procedures. Examples achieve these advantages by leveraging “discretized” patient-specific 3D brain structure representations to perform numerical methods for solving partial differential equations that estimate real-time (or close to real-time) temperature propagation within a patient's brain during a LITT procedure.

An artificial intelligence (Al) engine is trained on a plurality of annotated magnetic resonance (MR) images of a patient's brain. A plurality of MR images of a patient's head is provided. For each MR image in the plurality of provided MR images, the Al engine detects a plurality of edges of the brain and determine a biparietal diameter (BP) value, detects a plurality of frontal horn edges, and detects a plurality of occipital horn edges. A correction module determines that at least one detected edge is associated with a non -ventricular body and updates the edge to correspond to the applicable horn. The Al engine determines a frontal horn diameter (F) value, and a occipital horn diameter (O) value. An indication module provides an indication on abnormal dilation of the patient's brain ventricles based on a maximum F value, a maximum O value, and the maximum BP value.

The present invention relates to the field of magnetic resonance (MR) receive coil arrays 1, in particular to a magnetic receive coil array 1 with an additional sensor node 3. The sensor node 3 comprises a sensor 23 for collecting measurement data and a sensor signal acquisition circuit 25, which is configured to digitize the collected measurement data. The sensor signal acquisition circuit 25 is connected to a digital amplification signal acquisition circuit 16 via a first digital interface 27. The sensor signal acquisition circuit 25 is configured to link the digitized measurement data from the sensor signal acquisition circuit 25 to a digital amplifier 4 via the first digital interface 27, which is configured to combine the digitized measurement data from the sensor signal acquisition circuit 25 with an amplified digital MR signal. The MR receive coil array 1 comprises a merger circuit 6, which is configured to receive the combined digitized MR signal and the digitized measurement data from the digital amplifier 4 by a second digital interface 28 and to output the combined data to a back-end of an MR imaging system. Based on the additional data thus obtained by the sensor 23, an MR image can be improved. The invention also relates to an MR imaging device and a computer program product.

In an example, a method includes controlling electrical current to an actuation coil disposed about an elongate flexible body of a device within a field of view of magnetic resonance (MR) imaging system. The MR imaging system can be controlled to provide radio frequency pulses at one or more off-resonant frequencies to excite off-resonance spins near the actuation coil, such that the acquired MR data is representative of the off-resonance excitation. MR data can be provided based on MR signals acquired by the MR imaging system, in which at least some of the MR data includes the MR signals with the device within the field of view. Images can be reconstructed based on the MR data to provide reconstructed image data and localization data can be provided representative of at least one of a location, orientation and / or shape of the device based on the reconstructed image data.

A magnetic resonance imaging apparatus according to embodiments includes an imaging mechanism configured to perform MR imaging, and processing circuitry configured to control the imaging mechanism to perform shimming imaging to acquire a first magnetic field distribution map having a first spatial resolution, control the imaging mechanism to perform first MR imaging to acquire a first anatomical image having a second spatial resolution higher than the first spatial resolution, and generate a second magnetic field distribution map having a third spatial resolution higher than the first spatial resolution by using the first magnetic field distribution map, the first anatomical image, and / or a processed image having enhanced boundaries of anatomical regions included in the first anatomical image.

The invention discloses a Fe (III)-EGCG (epigallocatechin gallate) network coated copper sulfide nano-composite and application thereof, and belongs to the technical field of biological medicines. Polyethyleneimine is used as a nano-carrier, PEG-FA and FI are modified on the surface of the nano-carrier, CuS NPs is synthesized in situ in an internal cavity of the nano-carrier, residual amino groups on the surface of PEI.NH2 are functionalized through acetylation, and finally, FA-CuS PENs are coated with a metal polyphenol network Fe-EGCG, so that the nano-carrier is obtained. The Fe (III)-EGCG network coated copper sulfide nano-composite with the cancer cell MR imaging and chemical / photo-thermal / chemical kinetics combined treatment function is constructed. The nano-composite disclosed by the invention can realize high-amount uptake of cancer cells highly expressed by an FA receptor, and further realizes targeted cancer cell MR imaging and chemical / photo-thermal / chemical kinetics combined therapy.

The invention relates to a PET / MR attenuation correction method and system, and the method comprises the steps: S1, obtaining a Dixon FLASH sequence, carrying out the noise reduction reconstruction of the Dixon FLASH sequence through a depth reconstruction technology, and obtaining an MRI image through the magnetic resonance reconstruction decoding; s2, based on the MRI image, lung and human body contour segmentation is carried out to obtain lung tissue and air tissue, sCT image synthesis is carried out by adopting a neural network to obtain bone tissue, and soft tissue and adipose tissue are obtained through a Dixon water-fat separation technology; s3, respectively endowing specific attenuation coefficients to the masks of the five tissues, and synthesizing into an attenuation coefficient graph [mu] MAP for attenuation correction; and S4, carrying out attenuation correction on the PET raw data by adopting the attenuation coefficient graph [mu] MAP to obtain a final PET / MR imaging result. Compared with the prior art, the method has the advantages of high attenuation correction precision and high image acquisition efficiency.

According to the invention, a magnetic resonance (MR) receiver coil array (1) for an imaging system is provided, the MR receiver coil array (1) comprising at least one radio frequency (RF) receiver antenna (2), at least one digital amplifier signal acquisition unit (3), wherein the digital amplifier signal acquisition unit (3) is configured to receive an MR signal from the RF receiver antenna (2) and to output digital amplified MR data, at least one ultrasound transducer (5), wherein the ultrasound transducer (5) is acoustically couplable to an examination object (6), at least one ultrasound signal acquisition unit (7), wherein the ultrasound signal acquisition unit (7) is configured to receive an ultrasound signal from the ultrasound transducer (5) and to output digital ultrasound data, and a digital control and merge unit (8) comprising a controller module (9) and a merger module (10), wherein the controller module (9) is configured to generate control signals comprising a first control signal for the MR digital amplifier signal acquisition unit (3) and a second control signal for the ultrasound signal acquisition unit (7), and the merger module (10) is configured to receive the digital amplified MR data and the digital ultrasound data and to output the digital MR data and the digital ultrasound data to a digital data processing unit configured to combine the digital MR data and the digital ultrasound data to optimize the data acquisition and / or to optimize the image reconstruction. In this way, a possibility to combine and coordinate ultrasound imaging and MR imaging with each other for an improved image quality is provided.

The utility model provides a kind of PET-MR imaging quality detection multifunctional phantom, belong to PET / MR quality detection technical field, comprising: by inside to outside sequentially arranged uniformity detection module, PET / MR fusion degree test module, PET / MR resolution test module, PET / MR attenuation correction module;Uniformity detection module is by a cylindrical 68Ge-68Ga model body, 68Ge and epoxy resin and liquid polysulfide rubber are evenly mixed for simulating uniform radioactive division;PET / MR fusion degree test module includes hollow cylinder, when testing, inject Na source in hollow cylinder, carry out PET / MR scanning, obtain image fusion accuracy according to the obtained scanning image;It can be used for quality control to PET / MR imaging instrument, also can be used for finding the optimal scanning parameter of PET / MR imaging instrument, for teaching demonstration, for tracer screening etc., with wide application range.

This provides a macrocyclic complex for improving in vivo MR imaging. [Solution] A novel Fe(III) macrocyclic complex having a hydroxy pendant with a third anionic auxiliary is provided. This complex has the following general structure: TIFF2026136141000214.tif33169 High-spin Fe(III) is chelated into a macrocyclic core having the structure of formula (I) or formula (II).

The embodiment of the invention discloses a speech enhancement method and device in magnetic resonance imaging and a magnetic resonance imaging system. The method comprises the following steps: acquiring a time domain sound signal in an MR scanning room in real time; converting the time domain sound signal into a frequency domain to obtain a frequency domain sound signal; inputting the frequency domain sound signal into a band-pass filter of which the filtering bandwidth is equal to the filtering bandwidth of human auditory sense, and inputting the frequency domain sound signal after band-pass filtering into a first artificial intelligence module for noise elimination to obtain a first frequency domain clean sound signal; and converting the frequency domain first clean sound signal from the frequency domain to the time domain to obtain a time domain clean sound signal. According to the embodiment of the invention, the voice quality of internal communication in MR imaging is improved.

Disclosed in embodiments of the present invention are a motion correction method, apparatus, MR imaging system, and storage medium for MR imaging. The method comprises: obtaining a reference navigation image before acquiring MR data for a target region of interest; performing motion detection using pilot tone signals received by multiple coils during MR data acquisition for the target region of interest, and marking the MR data acquired when motion occurs as motion-damaged data when motion is detected; acquiring a post-motion navigation image when the pilot tone signal detects the end of the motion; registering the post-motion navigation image with the reference navigation image to obtain motion correction parameters corresponding to the motion; and performing motion correction on the MR data acquisition using the motion correction parameters. The technical solutions in the embodiments of the present invention can improve MR imaging quality.

The invention relates to a method of MR imaging of an object (10) placed in an examination volume of an MR system (1). It is an object of the invention to enable quantitative diffusion MR imaging based on the generation of a temporally incoherent MR signal evolution by variation of acquisition parameters (like in MRF or MR STAT). The method comprises the steps of: subjecting the object (10) to an imaging sequence composed of a train of sequence blocks, each sequence block comprising at least one RF pulse, at least one switched spoiling magnetic field gradient and at least one switched readout magnetic field gradient defining a k-space sampling pattern, and having associated therewith a set of acquisition parameters including the zeroth moment of the spoiling magnetic field gradient; acquiring the MR signals while varying at least the zeroth moment of the spoiling magnetic field gradient and, optionally, one or more further acquisition parameters during the course of the imaging sequence; and reconstructing at least one MR image, wherein at least a diffusion coefficient and, optionally, one or more further MR parameters are computed for a number of image positions from an incoherent temporal evolution of the acquired MR signals caused by the variation of the at least one acquisition parameter. Moreover, the invention relates to an MR system (1) for carrying out this method as well as to a computer program to be run on an MR system.

The disclosure is directed to an undersampled point restoration method, device and magnetic resonance imaging system in magnetic resonance imaging. The method may include, during magnetic resonance scanning of an imaging subject, acquiring magnetic resonance signals of each channel by an undersampling mode and respectively placing the acquired magnetic resonance signals of each channel into the K-space of the each channel; and for any undersampled point in the K-space of each channel of the imaging subject, restoring the undersampled point by performing high-order interpolation on data points surrounding the undersampled point. Aspects improve the accuracy of restoring undersampled points in MR imaging, thereby further enhancing the quality of MR images.

The invention relates to magnetic resonance, MR, imaging, comprising: subjecting one portion of an object (10) to a preparation sequence (PRE) comprising a spectrally selective adiabatic inversion radiofrequency, RF, pulse (21) having a flip angle (a) to selectively invert nuclear magnetization associated with fat protons; after a delay time (TD), subjecting the portion to an imaging sequence (IM) comprising one excitation RF pulse (28) to generate MR signals (27), wherein the delay time and / or the flip angle are determined such that contributions from a first spectral species of fat protons affected by the inversion RF pulse and a second spectral species of fat protons not affected by the inversion RF pulse to the MR signals substantially cancel each other out; acquiring the MR signals; and reconstructing an MR image from the MR signals, wherein contributions from both the first and second spectral species of fat protons are suppressed in the MR image.

The embodiment of the present application discloses a method and device for limiting radio frequency alternating magnetic field in magnetic resonance imaging. The method comprises: measuring the vertical distance between a local coil placed on the scanned part of a patient and the center of the detection hole of a magnetic resonance (MR) scanner; determining the deviation between the field strength of the B1 field at the position of the local coil and the field strength of the B1 field at the center of the detection hole according to the vertical distance; calculating the conversion coefficient between the field strength of the B1 field at the position of the local coil and the field strength of the B1 field at the center of the detection hole according to the deviation; and calculating the maximum allowable field strength of the B1 field at the center of the detection hole according to the field strength of the B1 field required when the surface temperature of the local coil is equal to the upper limit of the safe temperature and the conversion coefficient. The embodiment of the present application can limit the B1 field in a smaller but still effective field strength range, thereby reducing the waste of the performance of the B1 field while ensuring the safety of the patient and the quality of the MR imaging.

The invention relates to a method of MR imaging of an object (10) placed in an examination volume of an MR system (1). It is an object of the invention to enable an improved differentiation between abnormal / malignant tissue and tissue having a high water content in MR-EPT. The method of the invention comprises the following steps: generating MR signals by subjecting the object (10) to an imaging sequence comprising RF pulses and switched magnetic field gradients; acquiring the MR signals; reconstructing a magnitude MR image and a phase map from the MR signals for a given field of view within the object (10), which phase map is related to the spatial RF field distribution induced by the RF pulses within the field of view; deriving an electric conductivity map from the phase map, which electric conductivity map represents a measurement of the distribution of the electric conductivity within the field of view; deriving a further electric conductivity map from the magnitude MR image, which further electric conductivity map represents an estimation of the electric conductivity resulting from the distribution of water within the field of view; and identifying deviations of the two electric conductivity maps. Moreover, the invention relates to an MR system for carrying out this method as well as to a computer program to be run on an MR system.

The invention relates to a method of MR imaging of an object (10) placed in an examination volume of an MR system (1). It is an object of the invention to provide a method that enables improved MR imaging using partial echo acquisition. The method of the invention comprises the steps of: subjecting the object (10) to an imaging sequence comprising a series of RF excitations, wherein an echo signal is generated in the presence of a readout magnetic field gradient in each repetition time interval between successive RF excitations, wherein phase-encoding magnetic field gradients (P, S) are switched in each repetition time interval to sample a pre-defined region of k-space; acquiring the echo signals from the object (10) as partial echoes with different readout polarities, each echo signal being associated with either a first direction of the readout magnetic field gradient or a second direction of the readout magnetic field gradient which is opposite to the first direction, wherein the echo signals associated with the first and / or the second direction sample k-space sparsely in at least one phase-encoding direction (P, S); and reconstructing an MR image from the acquired echo signals. Furthermore, the invention proposes to apply a shift in k-space in the readout direction to the acquired echo signal data and to reconstruct an intermediate MR image for each of a number of different shift values, wherein a final MR image is computed from these intermediate MR images by selecting, for each voxel of the final MR image, the voxel value with the maximum intensity from the set of intermediate MR images at the respective voxel position. Signal loss caused by phase variations of the acquired partial echo signals can be avoided in this way. Moreover, the invention relates to an MR system (1) and to a computer program to be run on an MR system (1).

A pre-scanning determining method and apparatus, and a magnetic resonance imaging system. The method includes: scanning, after each magnetic resonance (MR) imaging scan ends and before a next MR imaging scan begins, an imaging target by using a pre-scanning determining sequence, and collecting a corresponding MR dataset according to a preset position and a preset quantity of a K-space line that needs to be collected; calculating, according to an MR dataset collected this time and an MR dataset collected last time by using the pre-scanning determining sequence, consistency between the two MR datasets; and determining, according to the consistency between the two MR datasets, whether pre-scanning needs to be performed before a next MR imaging scan begins.

The present invention relates to a method for acquiring magnetic resonance (MR) image datasets of at least two slices (S1, S2) by simultaneous multi-slice excitation. The method comprises: a) performing an MR imaging sequence using a multi-band radio frequency (RF) excitation pulse to simultaneously excite at least two slices (S1, S2) in at least two repetitions (Rep1, Rep2), wherein the repetitions are performed according to a phase modulation scheme, wherein each of the simultaneously excited slices is assigned a phase, and the phase of at least one of the simultaneously excited slices varies from one repetition to the next, thereby acquiring MR datasets of folded images (C1, C2) in each repetition; b) performing spatial registration (16) between at least two folded images (C1, C2); c) performing motion correction (18) on at least one MR dataset of the folded images (C1, C2); and d) reconstructing (20) MR images of at least two slices from the corrected MR datasets of the folded images.