155 results about "Mr imaging" patented technology

The invention discloses a renal clear cell carcinoma prognosis prediction method based on multi-mode MRI (Magnetic Resonance Imaging) image and digital pathological omics fusion. The method comprises the following steps: S1, collecting a training data set based on an MR image and a pathological image; s2, feature extraction of MR radiomics; s3, deep learning feature extraction of the pathological image; s4, an MR-pathological feature fusion module; and S5, deploying the network. According to the method, depth features with prognosis information are obtained from two scales of pre-treatment images and post-operation pathology, effective features are extracted by adopting image omics and a convolutional neural network mode according to data characteristics of MR images and pathology images, and depth fusion of the two types of features is completed in a hidden space through a multi-task guiding mode, so that the accuracy of the MR image and the pathology image is improved. A precise prognosis model with multi-scale information is provided, and the method has a relatively strong clinical application prospect and is of great significance for realizing precise immunotherapy and improving prognosis of a patient.

The invention relates to a method of MR imaging of an object positioned in the examination volume of an MR system (1). It is an object of the invention to provide a deep learning-based denoising approach that overcomes the Rician bias problem. As a solution, the invention proposes a method comprising the following steps: a) subjecting the object to an imaging sequence comprising RF pulses and switched magnetic field gradients, whereby MR signals are generated, b) acquiring the MR signals, c) reconstructing a complex-valued MR image from the acquired MR signals, d) denoising the MR image using a deep learning algorithm that operates on the real and the imaginary parts of the MR image, and c) computing a magnitude MR image from the denoised complex-valued MR image. According to an aspect of the invention, the deep learning algorithm uses a set of denoising models that are trained using different loss functions. In this way, a trade-off between noise removal and preservation of small image details can be controlled. Moreover, the invention relates to an MR system (1) and to a computer program for an MR system (1).

A computer-implemented method for transforming magnetic resonance (MR) imaging across multiple vendors is provided. The method comprises: obtaining a training dataset, wherein the training dataset comprises a paired dataset and an un-paired dataset, and wherein the training dataset comprises image data acquired using two or more MR imaging devices; training a deep network model using the training dataset; obtaining an input MR image; and transforming the input MR image to a target image style using the deep network model.

A device (18) configured to filter magnetic resonance (MR) signals includes, at least one electronic processor (24) programmed to: receive at least one MR signal (26) excited in a subject disposed in an MR imaging device (10); transform the at least one MR signal with a coherence function representing the at least one MR signal as an instantaneous frequency spectrum as a function of time: apply spectral filtering to the transformed at least one MR signal; and reconstruct at least one medical image from the filtered at least one MR signal.

The invention relates to a method of MR imaging of a body (10) of a patient positioned in an examination volume of an MR device (1). It is an object of the invention to provide a method that enables geometrically correct MR-only radiation therapy planning at minimum scan times. The method of the invention comprises the following steps: acquiring first MR imaging data representative of at least one region of the body (10); analyzing said first MR imaging data to delineate at least one anatomical structure within said body region; acquiring second MR imaging data of said body region using a multi-point Dixon sequence; deriving a B0 map from said second MR imaging data; analyzing said B0 map to determine at least one low fidelity region of said B0 map; performing B0 mapping to refine the B0 map using a multi-acquisition gradient echo sequence restricted to at least one region where said delineated anatomical structure and said low fidelity region overlap completely or partially; and correcting geometrical distortions in said first and / or second MR imaging data using the refined B0 map. Moreover, the invention relates to a MR device (1) for carrying out the method, and to a computer program to be executed on a MR device (1).

A method and a system include obtaining calibration scan data or low resolution images of a subject acquired with a magnetic resonance (MR) scanner of an MR imaging system. The method and the system also include inputting the calibration data or the low resolution images into a trained deep learning-based multi-mask segmentation network. The method and the system further include outputting labeled mask images for different anatomical stations, wherein a respective mask of a respective labeled mask image highlights an anatomical landmark of interest in each respective anatomical station of the different anatomical stations. The method and the system even further include determining an extent of a respective anatomical landmark of interest in each respective anatomical station of the different anatomical stations for a respective localizer scan for each respective anatomical station based at least on a respective label mask image for each respective anatomical station.

The invention provides a preparation method and application of a diagnosis and treatment agent for tumor radiotherapy sensitization, and belongs to the field of pharmacy. According to the method, a one-pot method is innovatively adopted to load D-mannose and manganese-coated gold nanoparticles (Au (at) MnO2NPs) into ZIF-8 nanoparticles, and the nano diagnosis and treatment agent (Dman / Au (at) MnO2ZIF-8) for tumor radiotherapy sensitization is prepared. The prepared composite nano diagnosis and treatment agent is enriched in tumor tissues by enhancing permeation and retention effects, releases D-mannose, gold nanoparticles and Mn < 2 + > capable of generating T1 magnetic resonance (MR) imaging signals, and realizes tumor radiotherapy sensitization under the guidance of MR imaging. Besides, D-mannose can further increase the sensitivity of tumor cells to ionizing radiation by inducing protein degradation of a tumor cell programmed death receptor-ligand 1, so that a synergistic treatment effect is achieved, and a new thought is expected to be provided for integration of radiotherapy sensitization and diagnosis and treatment of tumors.

The present disclosure describes a device, system, and methods for low-field magnetic resonance (MR) imaging. For example, a method for low-field MR imaging can include projecting a primary static magnetic field in a field of view, projecting a secondary static magnetic field to pre-polarize a first fluid moving toward the field of view, and acquiring a first image of the first fluid in the field of view based on a first RF pulse sequence. The method can further include projecting a tertiary static magnetic field to pre-polarize a second fluid moving toward the field of view and acquiring a second image of the second fluid in the field of view based on a second RF pulse sequence. The first image can be subtracted from the second image to generate a flow image of an object of interest positioned in the field of view.

The disclosure relates to a method for correcting a movement of an object occurring during an MR image acquisition. The method includes: determining a motion model describing possible movements of the object based on a defined number of degrees of freedom; detecting a motion of a marker provided on the object with a motion sensor; determining a description of the motion model in a common coordinate system; determining the motion of the marker in the common coordinate system; determining a first motion of the object in the common coordinate system using the description of the motion model, the first motion being the motion that best matches the determined motion of the marker in the common coordinate system using the defined number of degrees of freedom; and correcting the movement of the object based on the determined first motion in order to determine at least one motion corrected MR image.

The present invention relates to a method for MR imaging of an object (10) placed in an examination volume of an MR device (1). One object of the present invention is to achieve high-quality diffusion-weighted imaging (DWI) without distortion while minimizing artifacts caused by motion. The method of the present invention comprises the following steps: subjecting the object (10) to a dual-echo steady-state imaging sequence, generating a free induction decay signal (FID) and an echo signal (ECHO) in each interval between two consecutive RF pulses, wherein a pair of diffusion gradient waveforms (G) with equal phase integrals and opposite polarities are applied in the interval between the FID signal and the echo signal. DIF ); acquiring the FID signal and the echo signal in several repetitions of an imaging sequence with varying phase encoding; and reconstructing a diffusion-weighted MR image based on the acquired FID signal and echo signal. The present invention also relates to an MR device for performing the method and a computer program to be run on the MR device.

The invention belongs to the technical fields of medical chemistry, new materials and nanotechnology, and relates to a novel diagnosis and treatment agent in the field of interdisciplinary, in particular to a preparation method of a reduction response activation < 19 > F magnetic resonance signal amplification self-degradation nanometer diagnosis and treatment micelle. Poly (benzyl carbamate) is obtained through condensation polymerization as a basic structure, then chemical modification is performed to obtain a self-degradable fluorine-containing amphiphilic block polymer, hydrophobic drug chlorin (Ce6) is loaded through self-assembly, the self-degradable fluorine-containing amphiphilic block polymer has the characteristic of responding to degradation of glutathione (GSH) at a tumor site, and on the basis of maintaining self-degradation of a hydrophobic chain segment of the nano-micelle, the self-degradable fluorine-containing amphiphilic block polymer can be used for preparing the self-degradable fluorine-containing amphiphilic block polymer. The nano-micelle loaded with Ce6 has the advantages that the nano-micelle loaded with Ce6 is used as a carrier, the characteristic of efficient 19F MR imaging is additionally endowed, under laser irradiation, the nano-micelle loaded with Ce6 can enhance a new scheme of breast cancer photodynamic therapy, the effects of responding to tumor microenvironment self-degradation drug release and 19F MRI signal amplification are achieved, and therefore diagnosis and treatment integration of breast cancer is achieved.

A gradient coil unit surrounding a cylindrical patient receiving region and including a hollow cylindrical primary coil and a hollow cylindrical secondary coil surrounding the primary coil and the patient receiving region in a coaxial manner, having a first longitudinal end in a longitudinal direction, which is designed to receive an examination object, and a second longitudinal end lying opposite the first longitudinal end in the longitudinal direction, the primary coil having a first length in the longitudinal direction delimited by a first longitudinal position facing the first longitudinal end, and a second longitudinal position, the secondary coil having a second length delimited by a third longitudinal position facing the first longitudinal end, and a fourth longitudinal position, wherein the first length is shorter than the second length and the first longitudinal position has a greater spacing with respect to the first longitudinal end than the third longitudinal position.

Examples of the presently disclosed technology provide new systems and methods for real-time temperature propagation and tissue damage visualization during laser interstitial thermal therapy (LITT) procedures that do not rely on real-time MR imaging. Accordingly, examples enable performance of LITT procedures in regular operating rooms lacking MR-equipment—thereby reducing costs and improving availability for LITT procedures. Examples achieve these advantages by leveraging “discretized” patient-specific 3D brain structure representations to perform numerical methods for solving partial differential equations that estimate real-time (or close to real-time) temperature propagation within a patient's brain during a LITT procedure.

The invention relates to a method of MR imaging of an object (10) positioned in an examination volume of a MR device (1). It is an object of the invention to enable efficient spiral MR imaging without blurring artefacts, even in situations of strong B0 inhomogeneity. The method of the invention comprises the following steps: —subjecting the object (10) to an imaging sequence comprising at least one RF excitation pulse and modulated magnetic field gradients, —acquiring MR signals along two or more planar spiral k-space trajectories (31, 32, 33), wherein the radial k-space speed, i.e. the rate of variation of the radial distance from the spiral origin is essentially constant along each planar spiral k-space trajectory, and wherein the two or more k-space trajectories (31, 32, 33) are offset in-plane from each other, and—reconstructing an MR image from the acquired MR signals. Moreover, the invention relates to a MR device (1) and to a computer program for a MR device (1).

In a motion correction method, a reference navigation image is obtained before MR data collection is performed on a target region of interest; in a process of performing the MR data collection on the target region of interest, motion detection is performed using a pilot tone signal received by a plurality of coils, and when a motion is detected, MR data collected when the motion occurs is marked as motion damage data; a post-motion navigation image is obtained when the end of the motion is detected by utilizing the pilot tone signal; registration is performed on the post-motion navigation image and the reference navigation image to obtain a motion correction parameter corresponding to the motion; and motion correction on the MR data collection is performed using the motion correction parameter. The method according to the present disclosure advantageously improves MR imaging quality.

Examples of the presently disclosed technology provide new systems and methods for real-time temperature propagation and tissue damage visualization during laser interstitial thermal therapy (LITT) procedures that do not rely on real-time MR imaging. Accordingly, examples enable performance of LITT procedures in regular operating rooms lacking MR-equipment-thereby reducing costs and improving availability for LITT procedures. Examples achieve these advantages by leveraging “discretized” patient-specific 3D brain structure representations to perform numerical methods for solving partial differential equations that estimate real-time (or close to real-time) temperature propagation within a patient's brain during a LITT procedure.

According to a method, first MR reference data and first MR imaging data are captured. Further MR imaging data is then captured. The capturing includes in each case generating at least one excitation pulse with a transmit coil of the magnetic resonance apparatus and irradiating the at least one excitation pulse into a patient receiving region, generating MR signals in a generation region using the at least one excitation pulse, and receiving the MR signals as MR data with a receive coil. A degree of difference that describes a difference between the generation region on capture of the first MR reference data and the generation region on capture of the further MR imaging data is determined. MR reference data is provided as a function of the degree of difference. An MR image is reconstructed based on the captured further MR imaging data and the provided further MR reference data.

Various systems and computer-implemented methods for Radio Frequency (RF) coil attenuation correction are disclosed. PET time-of-flight (TOF) data generated by a PET imaging modality collocated with an MR imaging modality is received. RF coil attenuation data is extracted from the PET TOF data and an initial RF coil attenuation map is generated. A trained model configured to improve a signal to noise ratio of the initial RF coil attenuation map is applied to generate a final RF coil attenuation map. Attenuation correction of the PET TOF data is performed based on the final RF coil attenuation map. An image is reconstructed from attenuation corrected PET TOF data.

An artificial intelligence (Al) engine is trained on a plurality of annotated magnetic resonance (MR) images of a patient's brain. A plurality of MR images of a patient's head is provided. For each MR image in the plurality of provided MR images, the Al engine detects a plurality of edges of the brain and determine a biparietal diameter (BP) value, detects a plurality of frontal horn edges, and detects a plurality of occipital horn edges. A correction module determines that at least one detected edge is associated with a non -ventricular body and updates the edge to correspond to the applicable horn. The Al engine determines a frontal horn diameter (F) value, and a occipital horn diameter (O) value. An indication module provides an indication on abnormal dilation of the patient's brain ventricles based on a maximum F value, a maximum O value, and the maximum BP value.

The present invention relates to the field of magnetic resonance (MR) receive coil arrays 1, in particular to a magnetic receive coil array 1 with an additional sensor node 3. The sensor node 3 comprises a sensor 23 for collecting measurement data and a sensor signal acquisition circuit 25, which is configured to digitize the collected measurement data. The sensor signal acquisition circuit 25 is connected to a digital amplification signal acquisition circuit 16 via a first digital interface 27. The sensor signal acquisition circuit 25 is configured to link the digitized measurement data from the sensor signal acquisition circuit 25 to a digital amplifier 4 via the first digital interface 27, which is configured to combine the digitized measurement data from the sensor signal acquisition circuit 25 with an amplified digital MR signal. The MR receive coil array 1 comprises a merger circuit 6, which is configured to receive the combined digitized MR signal and the digitized measurement data from the digital amplifier 4 by a second digital interface 28 and to output the combined data to a back-end of an MR imaging system. Based on the additional data thus obtained by the sensor 23, an MR image can be improved. The invention also relates to an MR imaging device and a computer program product.

A method is for acquiring a magnetic resonance (MR) image dataset of at least two slices via simultaneous multi-slice excitation. An embodiment of the method includes executing an MR imaging sequence using multi-band radio-frequency excitation pulses to excite the at least two slices simultaneously in at least two repetitions, the repetitions each being executed according to a phase modulation scheme in which each of the simultaneously excited slices is assigned a phase and the phase of at least one of the simultaneously excited slices is changed from one repetition to the next, thereby acquiring an MR dataset of a collapsed image in each repetition; performing a spatial registration between the at least two collapsed images and performing motion correction on at least one of the MR datasets of the collapsed images; and reconstructing MR images of the at least two slices from the corrected MR datasets of the collapsed images.

In an example, a method includes controlling electrical current to an actuation coil disposed about an elongate flexible body of a device within a field of view of magnetic resonance (MR) imaging system. The MR imaging system can be controlled to provide radio frequency pulses at one or more off-resonant frequencies to excite off-resonance spins near the actuation coil, such that the acquired MR data is representative of the off-resonance excitation. MR data can be provided based on MR signals acquired by the MR imaging system, in which at least some of the MR data includes the MR signals with the device within the field of view. Images can be reconstructed based on the MR data to provide reconstructed image data and localization data can be provided representative of at least one of a location, orientation and / or shape of the device based on the reconstructed image data.

A magnetic resonance imaging apparatus according to embodiments includes an imaging mechanism configured to perform MR imaging, and processing circuitry configured to control the imaging mechanism to perform shimming imaging to acquire a first magnetic field distribution map having a first spatial resolution, control the imaging mechanism to perform first MR imaging to acquire a first anatomical image having a second spatial resolution higher than the first spatial resolution, and generate a second magnetic field distribution map having a third spatial resolution higher than the first spatial resolution by using the first magnetic field distribution map, the first anatomical image, and / or a processed image having enhanced boundaries of anatomical regions included in the first anatomical image.

In reconstruction, such as reconstruction in MR imaging, sub-sampled measurements from the scan are used in each iteration. By masking parts of the sub-sampled measurements (i.e., sub-sampling the acquired sub-sampled data) used in one or more iterations of reconstruction, banding is reduced or eliminated.

The invention discloses a Fe (III)-EGCG (epigallocatechin gallate) network coated copper sulfide nano-composite and application thereof, and belongs to the technical field of biological medicines. Polyethyleneimine is used as a nano-carrier, PEG-FA and FI are modified on the surface of the nano-carrier, CuS NPs is synthesized in situ in an internal cavity of the nano-carrier, residual amino groups on the surface of PEI.NH2 are functionalized through acetylation, and finally, FA-CuS PENs are coated with a metal polyphenol network Fe-EGCG, so that the nano-carrier is obtained. The Fe (III)-EGCG network coated copper sulfide nano-composite with the cancer cell MR imaging and chemical / photo-thermal / chemical kinetics combined treatment function is constructed. The nano-composite disclosed by the invention can realize high-amount uptake of cancer cells highly expressed by an FA receptor, and further realizes targeted cancer cell MR imaging and chemical / photo-thermal / chemical kinetics combined therapy.

The invention relates to a PET / MR attenuation correction method and system, and the method comprises the steps: S1, obtaining a Dixon FLASH sequence, carrying out the noise reduction reconstruction of the Dixon FLASH sequence through a depth reconstruction technology, and obtaining an MRI image through the magnetic resonance reconstruction decoding; s2, based on the MRI image, lung and human body contour segmentation is carried out to obtain lung tissue and air tissue, sCT image synthesis is carried out by adopting a neural network to obtain bone tissue, and soft tissue and adipose tissue are obtained through a Dixon water-fat separation technology; s3, respectively endowing specific attenuation coefficients to the masks of the five tissues, and synthesizing into an attenuation coefficient graph [mu] MAP for attenuation correction; and S4, carrying out attenuation correction on the PET raw data by adopting the attenuation coefficient graph [mu] MAP to obtain a final PET / MR imaging result. Compared with the prior art, the method has the advantages of high attenuation correction precision and high image acquisition efficiency.

According to the invention, a magnetic resonance (MR) receiver coil array (1) for an imaging system is provided, the MR receiver coil array (1) comprising at least one radio frequency (RF) receiver antenna (2), at least one digital amplifier signal acquisition unit (3), wherein the digital amplifier signal acquisition unit (3) is configured to receive an MR signal from the RF receiver antenna (2) and to output digital amplified MR data, at least one ultrasound transducer (5), wherein the ultrasound transducer (5) is acoustically couplable to an examination object (6), at least one ultrasound signal acquisition unit (7), wherein the ultrasound signal acquisition unit (7) is configured to receive an ultrasound signal from the ultrasound transducer (5) and to output digital ultrasound data, and a digital control and merge unit (8) comprising a controller module (9) and a merger module (10), wherein the controller module (9) is configured to generate control signals comprising a first control signal for the MR digital amplifier signal acquisition unit (3) and a second control signal for the ultrasound signal acquisition unit (7), and the merger module (10) is configured to receive the digital amplified MR data and the digital ultrasound data and to output the digital MR data and the digital ultrasound data to a digital data processing unit configured to combine the digital MR data and the digital ultrasound data to optimize the data acquisition and / or to optimize the image reconstruction. In this way, a possibility to combine and coordinate ultrasound imaging and MR imaging with each other for an improved image quality is provided.

The utility model provides a kind of PET-MR imaging quality detection multifunctional phantom, belong to PET / MR quality detection technical field, comprising: by inside to outside sequentially arranged uniformity detection module, PET / MR fusion degree test module, PET / MR resolution test module, PET / MR attenuation correction module;Uniformity detection module is by a cylindrical 68Ge-68Ga model body, 68Ge and epoxy resin and liquid polysulfide rubber are evenly mixed for simulating uniform radioactive division;PET / MR fusion degree test module includes hollow cylinder, when testing, inject Na source in hollow cylinder, carry out PET / MR scanning, obtain image fusion accuracy according to the obtained scanning image;It can be used for quality control to PET / MR imaging instrument, also can be used for finding the optimal scanning parameter of PET / MR imaging instrument, for teaching demonstration, for tracer screening etc., with wide application range.

This provides a macrocyclic complex for improving in vivo MR imaging. [Solution] A novel Fe(III) macrocyclic complex having a hydroxy pendant with a third anionic auxiliary is provided. This complex has the following general structure: TIFF2026136141000214.tif33169 High-spin Fe(III) is chelated into a macrocyclic core having the structure of formula (I) or formula (II).

The embodiment of the invention discloses a speech enhancement method and device in magnetic resonance imaging and a magnetic resonance imaging system. The method comprises the following steps: acquiring a time domain sound signal in an MR scanning room in real time; converting the time domain sound signal into a frequency domain to obtain a frequency domain sound signal; inputting the frequency domain sound signal into a band-pass filter of which the filtering bandwidth is equal to the filtering bandwidth of human auditory sense, and inputting the frequency domain sound signal after band-pass filtering into a first artificial intelligence module for noise elimination to obtain a first frequency domain clean sound signal; and converting the frequency domain first clean sound signal from the frequency domain to the time domain to obtain a time domain clean sound signal. According to the embodiment of the invention, the voice quality of internal communication in MR imaging is improved.