82 results about "Mr imaging" patented technology

The invention discloses a renal clear cell carcinoma prognosis prediction method based on multi-mode MRI (Magnetic Resonance Imaging) image and digital pathological omics fusion. The method comprises the following steps: S1, collecting a training data set based on an MR image and a pathological image; s2, feature extraction of MR radiomics; s3, deep learning feature extraction of the pathological image; s4, an MR-pathological feature fusion module; and S5, deploying the network. According to the method, depth features with prognosis information are obtained from two scales of pre-treatment images and post-operation pathology, effective features are extracted by adopting image omics and a convolutional neural network mode according to data characteristics of MR images and pathology images, and depth fusion of the two types of features is completed in a hidden space through a multi-task guiding mode, so that the accuracy of the MR image and the pathology image is improved. A precise prognosis model with multi-scale information is provided, and the method has a relatively strong clinical application prospect and is of great significance for realizing precise immunotherapy and improving prognosis of a patient.

The invention relates to a method of MR imaging of an object positioned in the examination volume of an MR system (1). It is an object of the invention to provide a deep learning-based denoising approach that overcomes the Rician bias problem. As a solution, the invention proposes a method comprising the following steps: a) subjecting the object to an imaging sequence comprising RF pulses and switched magnetic field gradients, whereby MR signals are generated, b) acquiring the MR signals, c) reconstructing a complex-valued MR image from the acquired MR signals, d) denoising the MR image using a deep learning algorithm that operates on the real and the imaginary parts of the MR image, and c) computing a magnitude MR image from the denoised complex-valued MR image. According to an aspect of the invention, the deep learning algorithm uses a set of denoising models that are trained using different loss functions. In this way, a trade-off between noise removal and preservation of small image details can be controlled. Moreover, the invention relates to an MR system (1) and to a computer program for an MR system (1).

The present disclosure describes a device, system, and methods for low-field magnetic resonance (MR) imaging. For example, a method for low-field MR imaging can include projecting a primary static magnetic field in a field of view, projecting a secondary static magnetic field to pre-polarize a first fluid moving toward the field of view, and acquiring a first image of the first fluid in the field of view based on a first RF pulse sequence. The method can further include projecting a tertiary static magnetic field to pre-polarize a second fluid moving toward the field of view and acquiring a second image of the second fluid in the field of view based on a second RF pulse sequence. The first image can be subtracted from the second image to generate a flow image of an object of interest positioned in the field of view.

The present invention relates to a method for MR imaging of an object (10) placed in an examination volume of an MR device (1). One object of the present invention is to achieve high-quality diffusion-weighted imaging (DWI) without distortion while minimizing artifacts caused by motion. The method of the present invention comprises the following steps: subjecting the object (10) to a dual-echo steady-state imaging sequence, generating a free induction decay signal (FID) and an echo signal (ECHO) in each interval between two consecutive RF pulses, wherein a pair of diffusion gradient waveforms (G) with equal phase integrals and opposite polarities are applied in the interval between the FID signal and the echo signal. DIF ); acquiring the FID signal and the echo signal in several repetitions of an imaging sequence with varying phase encoding; and reconstructing a diffusion-weighted MR image based on the acquired FID signal and echo signal. The present invention also relates to an MR device for performing the method and a computer program to be run on the MR device.

The invention belongs to the technical fields of medical chemistry, new materials and nanotechnology, and relates to a novel diagnosis and treatment agent in the field of interdisciplinary, in particular to a preparation method of a reduction response activation < 19 > F magnetic resonance signal amplification self-degradation nanometer diagnosis and treatment micelle. Poly (benzyl carbamate) is obtained through condensation polymerization as a basic structure, then chemical modification is performed to obtain a self-degradable fluorine-containing amphiphilic block polymer, hydrophobic drug chlorin (Ce6) is loaded through self-assembly, the self-degradable fluorine-containing amphiphilic block polymer has the characteristic of responding to degradation of glutathione (GSH) at a tumor site, and on the basis of maintaining self-degradation of a hydrophobic chain segment of the nano-micelle, the self-degradable fluorine-containing amphiphilic block polymer can be used for preparing the self-degradable fluorine-containing amphiphilic block polymer. The nano-micelle loaded with Ce6 has the advantages that the nano-micelle loaded with Ce6 is used as a carrier, the characteristic of efficient 19F MR imaging is additionally endowed, under laser irradiation, the nano-micelle loaded with Ce6 can enhance a new scheme of breast cancer photodynamic therapy, the effects of responding to tumor microenvironment self-degradation drug release and 19F MRI signal amplification are achieved, and therefore diagnosis and treatment integration of breast cancer is achieved.

A gradient coil unit surrounding a cylindrical patient receiving region and including a hollow cylindrical primary coil and a hollow cylindrical secondary coil surrounding the primary coil and the patient receiving region in a coaxial manner, having a first longitudinal end in a longitudinal direction, which is designed to receive an examination object, and a second longitudinal end lying opposite the first longitudinal end in the longitudinal direction, the primary coil having a first length in the longitudinal direction delimited by a first longitudinal position facing the first longitudinal end, and a second longitudinal position, the secondary coil having a second length delimited by a third longitudinal position facing the first longitudinal end, and a fourth longitudinal position, wherein the first length is shorter than the second length and the first longitudinal position has a greater spacing with respect to the first longitudinal end than the third longitudinal position.

The invention relates to a method of MR imaging of an object (10) positioned in an examination volume of a MR device (1). It is an object of the invention to enable efficient spiral MR imaging without blurring artefacts, even in situations of strong B0 inhomogeneity. The method of the invention comprises the following steps: —subjecting the object (10) to an imaging sequence comprising at least one RF excitation pulse and modulated magnetic field gradients, —acquiring MR signals along two or more planar spiral k-space trajectories (31, 32, 33), wherein the radial k-space speed, i.e. the rate of variation of the radial distance from the spiral origin is essentially constant along each planar spiral k-space trajectory, and wherein the two or more k-space trajectories (31, 32, 33) are offset in-plane from each other, and—reconstructing an MR image from the acquired MR signals. Moreover, the invention relates to a MR device (1) and to a computer program for a MR device (1).

Examples of the presently disclosed technology provide new systems and methods for real-time temperature propagation and tissue damage visualization during laser interstitial thermal therapy (LITT) procedures that do not rely on real-time MR imaging. Accordingly, examples enable performance of LITT procedures in regular operating rooms lacking MR-equipment-thereby reducing costs and improving availability for LITT procedures. Examples achieve these advantages by leveraging “discretized” patient-specific 3D brain structure representations to perform numerical methods for solving partial differential equations that estimate real-time (or close to real-time) temperature propagation within a patient's brain during a LITT procedure.

An artificial intelligence (Al) engine is trained on a plurality of annotated magnetic resonance (MR) images of a patient's brain. A plurality of MR images of a patient's head is provided. For each MR image in the plurality of provided MR images, the Al engine detects a plurality of edges of the brain and determine a biparietal diameter (BP) value, detects a plurality of frontal horn edges, and detects a plurality of occipital horn edges. A correction module determines that at least one detected edge is associated with a non -ventricular body and updates the edge to correspond to the applicable horn. The Al engine determines a frontal horn diameter (F) value, and a occipital horn diameter (O) value. An indication module provides an indication on abnormal dilation of the patient's brain ventricles based on a maximum F value, a maximum O value, and the maximum BP value.

In an example, a method includes controlling electrical current to an actuation coil disposed about an elongate flexible body of a device within a field of view of magnetic resonance (MR) imaging system. The MR imaging system can be controlled to provide radio frequency pulses at one or more off-resonant frequencies to excite off-resonance spins near the actuation coil, such that the acquired MR data is representative of the off-resonance excitation. MR data can be provided based on MR signals acquired by the MR imaging system, in which at least some of the MR data includes the MR signals with the device within the field of view. Images can be reconstructed based on the MR data to provide reconstructed image data and localization data can be provided representative of at least one of a location, orientation and / or shape of the device based on the reconstructed image data.

A magnetic resonance imaging apparatus according to embodiments includes an imaging mechanism configured to perform MR imaging, and processing circuitry configured to control the imaging mechanism to perform shimming imaging to acquire a first magnetic field distribution map having a first spatial resolution, control the imaging mechanism to perform first MR imaging to acquire a first anatomical image having a second spatial resolution higher than the first spatial resolution, and generate a second magnetic field distribution map having a third spatial resolution higher than the first spatial resolution by using the first magnetic field distribution map, the first anatomical image, and / or a processed image having enhanced boundaries of anatomical regions included in the first anatomical image.

The invention discloses a Fe (III)-EGCG (epigallocatechin gallate) network coated copper sulfide nano-composite and application thereof, and belongs to the technical field of biological medicines. Polyethyleneimine is used as a nano-carrier, PEG-FA and FI are modified on the surface of the nano-carrier, CuS NPs is synthesized in situ in an internal cavity of the nano-carrier, residual amino groups on the surface of PEI.NH2 are functionalized through acetylation, and finally, FA-CuS PENs are coated with a metal polyphenol network Fe-EGCG, so that the nano-carrier is obtained. The Fe (III)-EGCG network coated copper sulfide nano-composite with the cancer cell MR imaging and chemical / photo-thermal / chemical kinetics combined treatment function is constructed. The nano-composite disclosed by the invention can realize high-amount uptake of cancer cells highly expressed by an FA receptor, and further realizes targeted cancer cell MR imaging and chemical / photo-thermal / chemical kinetics combined therapy.

According to the invention, a magnetic resonance (MR) receiver coil array (1) for an imaging system is provided, the MR receiver coil array (1) comprising at least one radio frequency (RF) receiver antenna (2), at least one digital amplifier signal acquisition unit (3), wherein the digital amplifier signal acquisition unit (3) is configured to receive an MR signal from the RF receiver antenna (2) and to output digital amplified MR data, at least one ultrasound transducer (5), wherein the ultrasound transducer (5) is acoustically couplable to an examination object (6), at least one ultrasound signal acquisition unit (7), wherein the ultrasound signal acquisition unit (7) is configured to receive an ultrasound signal from the ultrasound transducer (5) and to output digital ultrasound data, and a digital control and merge unit (8) comprising a controller module (9) and a merger module (10), wherein the controller module (9) is configured to generate control signals comprising a first control signal for the MR digital amplifier signal acquisition unit (3) and a second control signal for the ultrasound signal acquisition unit (7), and the merger module (10) is configured to receive the digital amplified MR data and the digital ultrasound data and to output the digital MR data and the digital ultrasound data to a digital data processing unit configured to combine the digital MR data and the digital ultrasound data to optimize the data acquisition and / or to optimize the image reconstruction. In this way, a possibility to combine and coordinate ultrasound imaging and MR imaging with each other for an improved image quality is provided.

The utility model provides a kind of PET-MR imaging quality detection multifunctional phantom, belong to PET / MR quality detection technical field, comprising: by inside to outside sequentially arranged uniformity detection module, PET / MR fusion degree test module, PET / MR resolution test module, PET / MR attenuation correction module;Uniformity detection module is by a cylindrical 68Ge-68Ga model body, 68Ge and epoxy resin and liquid polysulfide rubber are evenly mixed for simulating uniform radioactive division;PET / MR fusion degree test module includes hollow cylinder, when testing, inject Na source in hollow cylinder, carry out PET / MR scanning, obtain image fusion accuracy according to the obtained scanning image;It can be used for quality control to PET / MR imaging instrument, also can be used for finding the optimal scanning parameter of PET / MR imaging instrument, for teaching demonstration, for tracer screening etc., with wide application range.

This provides a macrocyclic complex for improving in vivo MR imaging. [Solution] A novel Fe(III) macrocyclic complex having a hydroxy pendant with a third anionic auxiliary is provided. This complex has the following general structure: TIFF2026136141000214.tif33169 High-spin Fe(III) is chelated into a macrocyclic core having the structure of formula (I) or formula (II).

The embodiment of the invention discloses a speech enhancement method and device in magnetic resonance imaging and a magnetic resonance imaging system. The method comprises the following steps: acquiring a time domain sound signal in an MR scanning room in real time; converting the time domain sound signal into a frequency domain to obtain a frequency domain sound signal; inputting the frequency domain sound signal into a band-pass filter of which the filtering bandwidth is equal to the filtering bandwidth of human auditory sense, and inputting the frequency domain sound signal after band-pass filtering into a first artificial intelligence module for noise elimination to obtain a first frequency domain clean sound signal; and converting the frequency domain first clean sound signal from the frequency domain to the time domain to obtain a time domain clean sound signal. According to the embodiment of the invention, the voice quality of internal communication in MR imaging is improved.

Disclosed in embodiments of the present invention are a motion correction method, apparatus, MR imaging system, and storage medium for MR imaging. The method comprises: obtaining a reference navigation image before acquiring MR data for a target region of interest; performing motion detection using pilot tone signals received by multiple coils during MR data acquisition for the target region of interest, and marking the MR data acquired when motion occurs as motion-damaged data when motion is detected; acquiring a post-motion navigation image when the pilot tone signal detects the end of the motion; registering the post-motion navigation image with the reference navigation image to obtain motion correction parameters corresponding to the motion; and performing motion correction on the MR data acquisition using the motion correction parameters. The technical solutions in the embodiments of the present invention can improve MR imaging quality.

The disclosure is directed to an undersampled point restoration method, device and magnetic resonance imaging system in magnetic resonance imaging. The method may include, during magnetic resonance scanning of an imaging subject, acquiring magnetic resonance signals of each channel by an undersampling mode and respectively placing the acquired magnetic resonance signals of each channel into the K-space of the each channel; and for any undersampled point in the K-space of each channel of the imaging subject, restoring the undersampled point by performing high-order interpolation on data points surrounding the undersampled point. Aspects improve the accuracy of restoring undersampled points in MR imaging, thereby further enhancing the quality of MR images.

The invention relates to magnetic resonance, MR, imaging, comprising: subjecting one portion of an object (10) to a preparation sequence (PRE) comprising a spectrally selective adiabatic inversion radiofrequency, RF, pulse (21) having a flip angle (a) to selectively invert nuclear magnetization associated with fat protons; after a delay time (TD), subjecting the portion to an imaging sequence (IM) comprising one excitation RF pulse (28) to generate MR signals (27), wherein the delay time and / or the flip angle are determined such that contributions from a first spectral species of fat protons affected by the inversion RF pulse and a second spectral species of fat protons not affected by the inversion RF pulse to the MR signals substantially cancel each other out; acquiring the MR signals; and reconstructing an MR image from the MR signals, wherein contributions from both the first and second spectral species of fat protons are suppressed in the MR image.

The embodiment of the present application discloses a method and device for limiting radio frequency alternating magnetic field in magnetic resonance imaging. The method comprises: measuring the vertical distance between a local coil placed on the scanned part of a patient and the center of the detection hole of a magnetic resonance (MR) scanner; determining the deviation between the field strength of the B1 field at the position of the local coil and the field strength of the B1 field at the center of the detection hole according to the vertical distance; calculating the conversion coefficient between the field strength of the B1 field at the position of the local coil and the field strength of the B1 field at the center of the detection hole according to the deviation; and calculating the maximum allowable field strength of the B1 field at the center of the detection hole according to the field strength of the B1 field required when the surface temperature of the local coil is equal to the upper limit of the safe temperature and the conversion coefficient. The embodiment of the present application can limit the B1 field in a smaller but still effective field strength range, thereby reducing the waste of the performance of the B1 field while ensuring the safety of the patient and the quality of the MR imaging.

The invention relates to a method of MR imaging of an object (10) placed in an examination volume of an MR system (1). It is an object of the invention to enable an improved differentiation between abnormal / malignant tissue and tissue having a high water content in MR-EPT. The method of the invention comprises the following steps: generating MR signals by subjecting the object (10) to an imaging sequence comprising RF pulses and switched magnetic field gradients; acquiring the MR signals; reconstructing a magnitude MR image and a phase map from the MR signals for a given field of view within the object (10), which phase map is related to the spatial RF field distribution induced by the RF pulses within the field of view; deriving an electric conductivity map from the phase map, which electric conductivity map represents a measurement of the distribution of the electric conductivity within the field of view; deriving a further electric conductivity map from the magnitude MR image, which further electric conductivity map represents an estimation of the electric conductivity resulting from the distribution of water within the field of view; and identifying deviations of the two electric conductivity maps. Moreover, the invention relates to an MR system for carrying out this method as well as to a computer program to be run on an MR system.

The invention relates to a method of MR imaging of an object (10) placed in an examination volume of an MR system (1). It is an object of the invention to provide a method that enables improved MR imaging using partial echo acquisition. The method of the invention comprises the steps of: subjecting the object (10) to an imaging sequence comprising a series of RF excitations, wherein an echo signal is generated in the presence of a readout magnetic field gradient in each repetition time interval between successive RF excitations, wherein phase-encoding magnetic field gradients (P, S) are switched in each repetition time interval to sample a pre-defined region of k-space; acquiring the echo signals from the object (10) as partial echoes with different readout polarities, each echo signal being associated with either a first direction of the readout magnetic field gradient or a second direction of the readout magnetic field gradient which is opposite to the first direction, wherein the echo signals associated with the first and / or the second direction sample k-space sparsely in at least one phase-encoding direction (P, S); and reconstructing an MR image from the acquired echo signals. Furthermore, the invention proposes to apply a shift in k-space in the readout direction to the acquired echo signal data and to reconstruct an intermediate MR image for each of a number of different shift values, wherein a final MR image is computed from these intermediate MR images by selecting, for each voxel of the final MR image, the voxel value with the maximum intensity from the set of intermediate MR images at the respective voxel position. Signal loss caused by phase variations of the acquired partial echo signals can be avoided in this way. Moreover, the invention relates to an MR system (1) and to a computer program to be run on an MR system (1).

According to the invention, a method for selecting a set of coil elements of a radio frequency coil system (2) having a plurality of coil elements (4) for receiving magnetic resonance signals of a region of interest, the method comprising the following method steps: determining a signal-to-noise ratio ranking of the plurality of coil elements (4) for the region of interest; assigning the coil elements (4) to a first type A and a second type B on the basis of the determined signal-to-noise ratio ranking, coil elements having a signal-to-noise ratio higher than a predetermined threshold being assigned to the type A and coil elements having a signal-to-noise ratio lower than the predetermined threshold being assigned to the type B; determining a coupling effect of each coil element (4) of the radio frequency coil system (2) for the region of interest; grouping the coil elements (4) assigned to the first type A or the second type B into a primary coil group (8) and a secondary coil group (9) on the basis of the determined coupling effect and the signal-to-noise ratio, coil elements (4) of the same type A or B having a mutual coupling effect with each other being at least partially assigned into different coil groups (8, 9); and selecting the coil elements in the primary coil group (8) or the secondary coil group (9) for receiving the magnetic resonance signals of the region of interest. In this manner, the quality of MR imaging can be improved while avoiding simple exclusion of coil elements (4) that do not provide sufficient information content, but by selecting and combining the coil elements (4) such that the maximum possible number of coil elements (4) are used to receive electromagnetic induction signals while increasing SNR.

The embodiment of the invention discloses an under-sampling point recovery method and device in magnetic resonance imaging and a magnetic resonance imaging system. The method comprises the following steps: in the process of performing magnetic resonance scanning on an imaging target by adopting a multi-echo data imaging merging sequence, acquiring magnetic resonance signals of echoes of channels in an undersampling mode, and putting the acquired magnetic resonance signals of the echoes of the channels into K spaces of the echoes of the channels respectively, each channel has a plurality of echoes, and each echo of each channel corresponds to a K space; and for an under-sampling point in the K space of a specified echo of a specified channel of the imaging target, recovering the under-sampling point by adopting the magnetic resonance signals in the K spaces of the echoes of all channels and the magnetic resonance signals in the K spaces of other echoes of the specified channel. According to the embodiment of the invention, the under-sampling point recovery accuracy during MR imaging by adopting the MEDIC sequence is improved.

The invention relates to a method of MR imaging of an object (10) placed in a main magnetic field B0. It is an object of the invention to provide a method that enables an improved Dixon water / fat separation in combination with a multi-echo acquisition. The method of the invention comprises the following steps: The object (10) is subjected to an imaging sequence comprising multiple segments (S1, S2), each segment comprising at least one RF pulse followed by a phase-encoding magnetic field gradient and a series of bipolar readout magnetic field gradients applied during a readout period. Two or more phase-encoded echo signals are acquired during each readout period, each of the echo signals being associated with a different echo time resulting from the application of the series of bipolar readout magnetic field gradients. The phase-encoding and bipolar readout magnetic field gradients are controlled so as to sample a pre-determined k-space region with both positive and negative, i.e. opposite, readout directions for each echo time. Amplitude and / or phase errors are estimated from the echo signals acquired with opposite readout directions for each echo time. Finally, an MR image is reconstructed for each echo time involving correction of image distortions according to the estimated amplitude and / or phase errors. Moreover, the invention relates to an MR system (1) and to a computer program.

To avoid the influence of RF noise and external magnetic fields on the image quality of a portable magnetic resonance imaging (MRI) system (1). This is accomplished by providing a system and a computer-implemented method for determining an optimized position and / or orientation of a portable MRI system (1) for an MR imaging procedure in a medical environment (2), the system comprising: at least one RF noise sensor (3), the RF noise sensor (3) is configured for measuring RF noise in the medical environment (2) and providing sensor data; at least one magnetic field sensor (4), where the magnetic field sensor (4) is configured to measure the external magnetic field in the medical environment (2) and to provide sensor data; a processor unit (5) wherein the sensors (3, 4) are connected to the processor unit (5), the processor unit (5) comprising at least one memory (6) for storing instructions and at least one processor (7), the at least one processor is configured to execute the instructions such that the following are performed: measuring RF noise in the medical environment and the external magnetic field by means of a corresponding sensor (3, 4), evaluating the sensor data and creating a spatial distribution of the measured RF noise and / or the measured external magnetic field in the medical environment (2), a position and / or orientation of the portable MRI system (1) for an MR imaging procedure in the medical environment (2) is determined based on the measured RF noise and / or the spatial distribution of the measured external magnetic field.

Embodiments of the present application disclose a multi-echo data magnetic resonance imaging scanning method, device and magnetic resonance imaging system. The method comprises: in the process of multi-echo data magnetic resonance imaging scanning on an imaging target, if automatic calibration data needs to be collected in the current repetition time, and the position of the automatic calibration data in K space is inconsistent with the position of any imaging data in K space which needs to be collected in the current repetition time, then: when the plateau signal of the first readout gradient in the readout direction is applied, start to apply an offset gradient in the phase encoding direction, wherein the first readout gradient is any readout gradient in the readout direction except the last readout gradient; and during the application of the plateau signal of the dephasing gradient of the first readout gradient in the readout direction, the automatic calibration data is collected. Embodiments of the present application avoid TR oscillation in multi-echo data MR imaging scanning, and realize the continuity of the collected automatic calibration data and imaging data.

A method and a system include obtaining calibration scan data or low resolution images of a subject acquired with a magnetic resonance (MR) scanner of an MR imaging system. The method and the system also include inputting the calibration data or the low resolution images into a trained deep learning-based multi-mask segmentation network. The method and the system further include outputting labeled mask images for different anatomical stations, wherein a respective mask of a respective labeled mask image highlights an anatomical landmark of interest in each respective anatomical station of the different anatomical stations. The method and the system even further include determining an extent of a respective anatomical landmark of interest in each respective anatomical station of the different anatomical stations for a respective localizer scan for each respective anatomical station based at least on a respective label mask image for each respective anatomical station.

A method for combined PET / MR imaging performs a PET / MR scan using a PET / MR scanner. During the scan a frame is reconstructed and co-registered with a reference frame. The reference frame is dynamically updated throughout the PET / MR scan by incorporating most recently co-registered images from previously reconstructed frames.

Systems and methods for adaptive radiation therapy planning are provided. In some aspects, the provided systems and methods include generating a synthetic image from magnetic resonance data using relaxation mapping. The method includes applying corrections to the data and generating a relaxation map therefrom. In other aspects, a method for adapting a radiation therapy plan is provided. The method includes determining an objective function based on a dose gradient from an initial dose distribution and generating an optimized plan based on updated images using an aperture deformation and gradient maintenance algorithm without contouring of organs at risk. In still other aspects, methods are provided for obtaining 4D MR imaging using temporal shuffling of data acquired during normal breathing, methods for deformable image registration using a semi-physical model regularization method applied sequentially to multimodal images, and methods for generating a 4D plan based on 4D CT or 4D MR imaging using an aperture deformation algorithm.