883 results about "Mr imaging" patented technology

The invention relates to an MR imaging method for representing and determining the position of a medical device inserted in an examination object, and to a medical device used in the method. In accordance with the invention, the device (11) comprises at least one passive oscillating circuit with an inductor (2a, 2b) and a capacitor (3a, 3b). The resonance frequency of this circuit substantially corresponds to the resonance frequency of the injected high-frequency radiation from the MR system. In this way, in a locally limited area situated inside or around the device, a modified signal answer is generated which is represented with spatial resolution.

This invention discloses a method and apparatus to deliver medical devices to targeted locations within human tissues using imaging data. The method enables the target location to be obtained from one imaging system, followed by the use of a second imaging system to verify the final position of the device. In particular, the invention discloses a method based on the initial identification of tissue targets using MR imaging, followed by the use of ultrasound imaging to verify and monitor accurate needle positioning. The invention can be used for acquiring biopsy samples to determine the grade and stage of cancer in various tissues including the brain, breast, abdomen, spine, liver, and kidney. The method is also useful for delivery of markers to a specific site to facilitate surgical removal of diseased tissue, or for the targeted delivery of applicators that destroy diseased tissues in-situ.

Tomography limitations in vivo due to incomplete, inconsistent and intricate measurements require solution of inverse problems. The new strategies disclosed in this application are capable of providing faster data acquisition, higher image quality, lower radiation dose, greater flexibility, and lower system cost. Such benefits can be used to advance research in cardiovascular diseases, regenerative medicine, inflammation, and nanotechnology. The present invention relates to the field of medical imaging. More particularly, embodiments of the invention relate to methods, systems, and devices for imaging, including tomography-based and MRI-based applications. For example, included in embodiments of the invention are compressive sampling based tomosynthesis methods, which have great potential to reduce the overall x-ray radiation dose for a patient. To name a few, compressive sensing based carbon nano-tube based interior tomosynthesis systems, tomography-based dynamic cardiac elastography systems, cardiac elastodynamic biomarkers from interior MR imaging, exact and stable interior ROI reconstructions for radial MRI, and interior reconstruction based ultrafast tomography systems are provided.

A system for magnetically imaging an operating region in a subject and magnetically navigating a medical device within the operating region includes a first magnet for applying a static magnetic field to the operating region of sufficient strength for magnetically imaging the operating region and sufficiently strong to permit a medical device to be oriented in the operating region by creating a magnetic moment at the distal end of the medical device, and a second magnet for applying a static magnetic field to the operating region of sufficient strength for magnetically imaging the operating region and sufficiently strong to permit a medical device to be oriented in the operating region by creating a magnetic moment at the distal end of the medical device. In an alternate construction, the system includes a first magnet that is movable between a first position to apply a first static magnetic field to the operating region and a second position to apply a second static magnetic field to the operating region. The method of the invention includes applying a first static magnetic field to the operating region and MR imaging and magnetically navigating a device in the first static field, and then applying a second static magnetic field to the operating region, in a different direction than the first direction, and MR imaging and magnetically navigating a device in the second static field.

A magnetic resonance-electrical impedance tomography (MREIT) technique for determining the local conductivity of an object. The MREIT technique combines magnetic resonance current density imaging (MRCDI) with electrical impedance tomography (EIT) in order to obtain the benefits of both procedures. The MREIT technique includes the step of current density imaging by performing the steps of placing a series of electrodes around the patient or object to be imaged for the application of current, placing the patient or object in a strong magnetic field, and applying an MR imaging sequence which is synchronized with the application of current through the electrodes. Next, the electric potentials of the surface of the object or patient are measured simultaneously with the MR imaging sequence, as in EIT. Then, the MR imaging signal containing information about the current and the measured potential are processed to calculate the internal conductivity (impedance) of the object or patient.

The present invention provides a method of magnetic resonance investigation of a sample, preferably of a human or non-human animal body, said method comprising the step of ex vivo polarisation of a high T1 agent and wherein the polarising agent is optionally seperated from the high T1 agent before the high T1 agent is administered to the sample.

A passive resonant circuit is disposed on an implanted stent. The materials, geomentry and electrical parameters of the stent with passive resonant circuit are chosen and arranged so that incident electromagnetic radiation induces currents in the passive resonant circuit that optimize imageability during MR scanning.

An imaging marker comprised of glass and iron-containing aluminum microspheres in a gel matrix which shows uniformly good contrast with MR, US and X-Ray imaging. The marker is small and can be easily introduced into tissue through a 12-gauge biopsy needle. The concentration of glass microspheres and the size dictate the contrast for US imaging. The contrast seen in MRI resulting from susceptibility losses is dictated by the number of iron-containing aluminum microspheres; while the artifact of the marker also depends on its shape, orientation and echo time. By optimizing the size, iron concentration and gel binding, an implantable tissue marker is created which is clearly visible with all three imaging modalities.

A magnetic resonance imaging system includes an MR signal reception apparatus comprising a receiving multi-coil and a switchover member. The receiving multi-coil receives MR signals and is composed of a plurality of element coils. The switchover member is configured to switch reception states of the MR signals received by the plurality of element coils in response to imaging conditions. The switchover member connects output paths of the MR signals from the plurality of element coils to a receiver, to reception channels in the receiver in response to the imaging conditions. The reception channels is less in number than the element coils. The imaging conditions are for example directed to parallel MR imaging.

Techniques for temperature measurement and correction in long-term MR thermometry utilize a known temperature distribution in an MR imaging area as a baseline for absolute temperature measurement. Phase shifts that arise from magnetic field drifts are detected in one or more portions of the MR imaging area, facilitating correction of temperature measurements in an area of interest.

Disclosed are carriers for drugs and/or MR imaging agents having a lipid bilayer shell comprising a phospholipid having two terminal alkyl chains, one being a short chain having a chain length of at most seven carbon atoms, the other being a long chain having a chain length of at least fifteen carbon atoms. The mixed long/short chain phospholipids serve to tune the release properties of the carrier. Preferred phospholipids are phosphatidylcholines.

An RF coil for MR Imaging that can change a resonance frequency easily and instantaneously in response to a nuclide to be imaged without exchange and adjustment and that also causes only small lowering of sensitivity. The RF coil has a sub coil for changing a resonance frequency of the transmitting/receiving RF coil for transmitting and receiving an MR signal between itself and a nuclide that is an object to be imaged. The sub coil is equipped with a switch, and at the time of switching-on, shifts the resonance frequency of the RF coil by changing an inductance value of the RF coil in a noncontact manner using inductance coupling.

The invention provides for methods for producing water-soluble iron oxide nanoparticles comprising encapsulating the nanoparticles in phospholipids micelles. Also provided are methods for conjugating the inventive nanoparticles via functionalized phospholipids to a target molecule, such as an antibody. The invention further provides methods for using the nanoparticle-antibody conjugate of the invention as a contrast agent to image specific cells or proteins in a subject using fluorescent and magnetic imaging techniques.

In a method and apparatus for MR imaging, a data acquisition sequence is executed wherein at least two slices of an examination subject are imaged in parallel with a gradient echo method for spatially resolved quantification of the T1 relaxation time.

At least one first acquisition sequence is implemented to acquire MR data from a first slice of the examination subject and at least one second acquisition sequence is implemented to acquire MR data from a second slice of the examination subject. The acquisition sequences each include an inversion pulse and at least two successive readout steps. The first and second acquisition sequences are temporally offset from one another such that they at least partially overlap.

A system for detecting electromagnetic noise in a magnetic resonance imaging (MRI) scanner environment includes an antenna configured to detect electromagnetic noise. The antenna includes a first conducting loop and a second conducting loop oriented perpendicularly to the first conducting loop. The system also includes a noise correction system coupled to the antenna and configured to receive noise signals from the antenna.

A method of calibrating an imaging sequence includes the application of a pre-scan pulse sequence to acquire MR signals from a region-of-interest to be imaged with an imaging pulse sequence. The pre-scan pulse sequence is interrupted to acquire pre-scan data in a low bandwidth acquisition window. A frequency spectrum is generated from the pre-scan data and displayed to interactively allow a user to establish scan parameters for the imaging pulse sequence.

The invention relates to a vessel filter comprising at least one conductor loop (21) which forms the inductance of an electric resonance circuit. According to the invention, the conductor loop (21) forms the vessel filter or parts of a vessel filter. The invention provides a vessel filter which is characterized by good mechanical properties, especially a high degree of flexibility and stability, offering good representability in MR imaging systems.

The invention provides a novel way of handling electric or electromagnetic signals during magnetic resonance (MR) measurements. Non-MR data signals such as EPH signals (e.g. EEG, ECG, blood pressure, respiration) or subject responses (e.g. keystrokes, joystick movements) originating in the MR suite is recorded while performing magnetic resonance imaging or spectroscopy. Relatively simple, possibly battery driven hardware is used to transform the non-MR signals into radio waves detectable by the MR apparatus. The electrical signals are in this way encoded as artifacts appearing in the MR images or spectra outside the region of interest, and the encoded signals can subsequently be reconstructed from the signal recorded by the scanner If oversampling is employed, artifacts can be avoided altogether. The method inherently provides superior synchronisation between the sampling of non-MR data signals and the MR sequence. The invention minimises the need for costly special MR adapted equipment and can be applied with scanners for MR imaging as well as with NMR spectrometers.

The invention is an apparatus and method for treatments and targeted drug delivery into a living patient, particularly but not exclusively using magnetic resonance (MR) imaging. The apparatus and method are useful in delivery to all types of living tissue and uses MR Imaging to track the location of drug delivery and estimating the rate of drug delivery. An MR-visible drug delivery device positioned at a target site (e.g., intracranial delivery) delivers a diagnostic or therapeutic drug solution into the tissue (e.g., the brain). The spinal distribution kinetics of the injected or infused drug agent are monitored quantitatively and non-invasively using water proton directional diffusion MR imaging to establish the efficacy of drug delivery at a targeted location.