40 results about "Mr imaging" patented technology

The invention relates to a method of MR imaging of an object (10) positioned in an examination volume of a MR device (1). It is an object of the invention to enable efficient spiral MR imaging without blurring artefacts, even in situations of strong B0 inhomogeneity. The method of the invention comprises the following steps: —subjecting the object (10) to an imaging sequence comprising at least one RF excitation pulse and modulated magnetic field gradients, —acquiring MR signals along two or more planar spiral k-space trajectories (31, 32, 33), wherein the radial k-space speed, i.e. the rate of variation of the radial distance from the spiral origin is essentially constant along each planar spiral k-space trajectory, and wherein the two or more k-space trajectories (31, 32, 33) are offset in-plane from each other, and—reconstructing an MR image from the acquired MR signals. Moreover, the invention relates to a MR device (1) and to a computer program for a MR device (1).

Examples of the presently disclosed technology provide new systems and methods for real-time temperature propagation and tissue damage visualization during laser interstitial thermal therapy (LITT) procedures that do not rely on real-time MR imaging. Accordingly, examples enable performance of LITT procedures in regular operating rooms lacking MR-equipment-thereby reducing costs and improving availability for LITT procedures. Examples achieve these advantages by leveraging “discretized” patient-specific 3D brain structure representations to perform numerical methods for solving partial differential equations that estimate real-time (or close to real-time) temperature propagation within a patient's brain during a LITT procedure.

An artificial intelligence (Al) engine is trained on a plurality of annotated magnetic resonance (MR) images of a patient's brain. A plurality of MR images of a patient's head is provided. For each MR image in the plurality of provided MR images, the Al engine detects a plurality of edges of the brain and determine a biparietal diameter (BP) value, detects a plurality of frontal horn edges, and detects a plurality of occipital horn edges. A correction module determines that at least one detected edge is associated with a non -ventricular body and updates the edge to correspond to the applicable horn. The Al engine determines a frontal horn diameter (F) value, and a occipital horn diameter (O) value. An indication module provides an indication on abnormal dilation of the patient's brain ventricles based on a maximum F value, a maximum O value, and the maximum BP value.

A magnetic resonance imaging apparatus according to embodiments includes an imaging mechanism configured to perform MR imaging, and processing circuitry configured to control the imaging mechanism to perform shimming imaging to acquire a first magnetic field distribution map having a first spatial resolution, control the imaging mechanism to perform first MR imaging to acquire a first anatomical image having a second spatial resolution higher than the first spatial resolution, and generate a second magnetic field distribution map having a third spatial resolution higher than the first spatial resolution by using the first magnetic field distribution map, the first anatomical image, and / or a processed image having enhanced boundaries of anatomical regions included in the first anatomical image.

The invention discloses a Fe (III)-EGCG (epigallocatechin gallate) network coated copper sulfide nano-composite and application thereof, and belongs to the technical field of biological medicines. Polyethyleneimine is used as a nano-carrier, PEG-FA and FI are modified on the surface of the nano-carrier, CuS NPs is synthesized in situ in an internal cavity of the nano-carrier, residual amino groups on the surface of PEI.NH2 are functionalized through acetylation, and finally, FA-CuS PENs are coated with a metal polyphenol network Fe-EGCG, so that the nano-carrier is obtained. The Fe (III)-EGCG network coated copper sulfide nano-composite with the cancer cell MR imaging and chemical / photo-thermal / chemical kinetics combined treatment function is constructed. The nano-composite disclosed by the invention can realize high-amount uptake of cancer cells highly expressed by an FA receptor, and further realizes targeted cancer cell MR imaging and chemical / photo-thermal / chemical kinetics combined therapy.

According to the invention, a magnetic resonance (MR) receiver coil array (1) for an imaging system is provided, the MR receiver coil array (1) comprising at least one radio frequency (RF) receiver antenna (2), at least one digital amplifier signal acquisition unit (3), wherein the digital amplifier signal acquisition unit (3) is configured to receive an MR signal from the RF receiver antenna (2) and to output digital amplified MR data, at least one ultrasound transducer (5), wherein the ultrasound transducer (5) is acoustically couplable to an examination object (6), at least one ultrasound signal acquisition unit (7), wherein the ultrasound signal acquisition unit (7) is configured to receive an ultrasound signal from the ultrasound transducer (5) and to output digital ultrasound data, and a digital control and merge unit (8) comprising a controller module (9) and a merger module (10), wherein the controller module (9) is configured to generate control signals comprising a first control signal for the MR digital amplifier signal acquisition unit (3) and a second control signal for the ultrasound signal acquisition unit (7), and the merger module (10) is configured to receive the digital amplified MR data and the digital ultrasound data and to output the digital MR data and the digital ultrasound data to a digital data processing unit configured to combine the digital MR data and the digital ultrasound data to optimize the data acquisition and / or to optimize the image reconstruction. In this way, a possibility to combine and coordinate ultrasound imaging and MR imaging with each other for an improved image quality is provided.

The utility model provides a kind of PET-MR imaging quality detection multifunctional phantom, belong to PET / MR quality detection technical field, comprising: by inside to outside sequentially arranged uniformity detection module, PET / MR fusion degree test module, PET / MR resolution test module, PET / MR attenuation correction module;Uniformity detection module is by a cylindrical 68Ge-68Ga model body, 68Ge and epoxy resin and liquid polysulfide rubber are evenly mixed for simulating uniform radioactive division;PET / MR fusion degree test module includes hollow cylinder, when testing, inject Na source in hollow cylinder, carry out PET / MR scanning, obtain image fusion accuracy according to the obtained scanning image;It can be used for quality control to PET / MR imaging instrument, also can be used for finding the optimal scanning parameter of PET / MR imaging instrument, for teaching demonstration, for tracer screening etc., with wide application range.

This provides a macrocyclic complex for improving in vivo MR imaging. [Solution] A novel Fe(III) macrocyclic complex having a hydroxy pendant with a third anionic auxiliary is provided. This complex has the following general structure: TIFF2026136141000214.tif33169 High-spin Fe(III) is chelated into a macrocyclic core having the structure of formula (I) or formula (II).

The disclosure is directed to an undersampled point restoration method, device and magnetic resonance imaging system in magnetic resonance imaging. The method may include, during magnetic resonance scanning of an imaging subject, acquiring magnetic resonance signals of each channel by an undersampling mode and respectively placing the acquired magnetic resonance signals of each channel into the K-space of the each channel; and for any undersampled point in the K-space of each channel of the imaging subject, restoring the undersampled point by performing high-order interpolation on data points surrounding the undersampled point. Aspects improve the accuracy of restoring undersampled points in MR imaging, thereby further enhancing the quality of MR images.

The embodiment of the present application discloses a method and device for limiting radio frequency alternating magnetic field in magnetic resonance imaging. The method comprises: measuring the vertical distance between a local coil placed on the scanned part of a patient and the center of the detection hole of a magnetic resonance (MR) scanner; determining the deviation between the field strength of the B1 field at the position of the local coil and the field strength of the B1 field at the center of the detection hole according to the vertical distance; calculating the conversion coefficient between the field strength of the B1 field at the position of the local coil and the field strength of the B1 field at the center of the detection hole according to the deviation; and calculating the maximum allowable field strength of the B1 field at the center of the detection hole according to the field strength of the B1 field required when the surface temperature of the local coil is equal to the upper limit of the safe temperature and the conversion coefficient. The embodiment of the present application can limit the B1 field in a smaller but still effective field strength range, thereby reducing the waste of the performance of the B1 field while ensuring the safety of the patient and the quality of the MR imaging.

The invention relates to a method of MR imaging of an object (10) placed in an examination volume of an MR system (1). It is an object of the invention to provide a method that enables improved MR imaging using partial echo acquisition. The method of the invention comprises the steps of: subjecting the object (10) to an imaging sequence comprising a series of RF excitations, wherein an echo signal is generated in the presence of a readout magnetic field gradient in each repetition time interval between successive RF excitations, wherein phase-encoding magnetic field gradients (P, S) are switched in each repetition time interval to sample a pre-defined region of k-space; acquiring the echo signals from the object (10) as partial echoes with different readout polarities, each echo signal being associated with either a first direction of the readout magnetic field gradient or a second direction of the readout magnetic field gradient which is opposite to the first direction, wherein the echo signals associated with the first and / or the second direction sample k-space sparsely in at least one phase-encoding direction (P, S); and reconstructing an MR image from the acquired echo signals. Furthermore, the invention proposes to apply a shift in k-space in the readout direction to the acquired echo signal data and to reconstruct an intermediate MR image for each of a number of different shift values, wherein a final MR image is computed from these intermediate MR images by selecting, for each voxel of the final MR image, the voxel value with the maximum intensity from the set of intermediate MR images at the respective voxel position. Signal loss caused by phase variations of the acquired partial echo signals can be avoided in this way. Moreover, the invention relates to an MR system (1) and to a computer program to be run on an MR system (1).

The embodiment of the invention discloses an under-sampling point recovery method and device in magnetic resonance imaging and a magnetic resonance imaging system. The method comprises the following steps: in the process of performing magnetic resonance scanning on an imaging target by adopting a multi-echo data imaging merging sequence, acquiring magnetic resonance signals of echoes of channels in an undersampling mode, and putting the acquired magnetic resonance signals of the echoes of the channels into K spaces of the echoes of the channels respectively, each channel has a plurality of echoes, and each echo of each channel corresponds to a K space; and for an under-sampling point in the K space of a specified echo of a specified channel of the imaging target, recovering the under-sampling point by adopting the magnetic resonance signals in the K spaces of the echoes of all channels and the magnetic resonance signals in the K spaces of other echoes of the specified channel. According to the embodiment of the invention, the under-sampling point recovery accuracy during MR imaging by adopting the MEDIC sequence is improved.

Embodiments of the present application disclose a multi-echo data magnetic resonance imaging scanning method, device and magnetic resonance imaging system. The method comprises: in the process of multi-echo data magnetic resonance imaging scanning on an imaging target, if automatic calibration data needs to be collected in the current repetition time, and the position of the automatic calibration data in K space is inconsistent with the position of any imaging data in K space which needs to be collected in the current repetition time, then: when the plateau signal of the first readout gradient in the readout direction is applied, start to apply an offset gradient in the phase encoding direction, wherein the first readout gradient is any readout gradient in the readout direction except the last readout gradient; and during the application of the plateau signal of the dephasing gradient of the first readout gradient in the readout direction, the automatic calibration data is collected. Embodiments of the present application avoid TR oscillation in multi-echo data MR imaging scanning, and realize the continuity of the collected automatic calibration data and imaging data.

A method and a system include obtaining calibration scan data or low resolution images of a subject acquired with a magnetic resonance (MR) scanner of an MR imaging system. The method and the system also include inputting the calibration data or the low resolution images into a trained deep learning-based multi-mask segmentation network. The method and the system further include outputting labeled mask images for different anatomical stations, wherein a respective mask of a respective labeled mask image highlights an anatomical landmark of interest in each respective anatomical station of the different anatomical stations. The method and the system even further include determining an extent of a respective anatomical landmark of interest in each respective anatomical station of the different anatomical stations for a respective localizer scan for each respective anatomical station based at least on a respective label mask image for each respective anatomical station.

The invention provides a magnetic resonance imaging repeated scanning consistent positioning method and system based on image guidance, and a terminal, and is applied to magnetic resonance scanning positioning to obtain a low-resolution reference guidance image and an initial positioning image used for positioning a region of interest. Collecting a guide image at the current moment, registering the guide image with the low-resolution reference guide image, and calculating a current positioning parameter of the region of interest at the current moment; and based on the current positioning parameter input in real time, the magnetic resonance scanning control system performs main sequence scanning to obtain a current main sequence image. The technical problems that in the prior art, in magnetic resonance imaging, in the field of repeated scanning positioning, fine signals are weakened through post-registration, positioning deviation is caused by body movement, and the imaging efficiency and the imaging effect are difficult to consider at the same time are solved. According to the method, extra hardware support is not needed, and the technical scheme of accurate, efficient and consistent positioning can be realized, so that the high-precision and high-stability requirements of scenes such as early disease diagnosis and longitudinal scientific research tracking on magnetic resonance imaging are met.

The embodiment of the invention discloses an under-sampling point recovery method and device in magnetic resonance imaging and a magnetic resonance imaging system. The method comprises the following steps: in the process of performing magnetic resonance scanning on an imaging target, acquiring magnetic resonance signals of each channel in an undersampling mode, and putting the acquired magnetic resonance signals of each channel into a K space of each channel; and for any under-sampling point in the K space of each channel of the imaging target, recovering the under-sampling point by adopting a mode of performing high-order interpolation on the surrounding data points of the under-sampling point. According to the embodiment of the invention, the recovery accuracy of the under-sampling point in MR imaging is improved, so that the quality of the MR image is further improved.

To improve the quality of imaging data collected by MR imaging. [Solution] The magnetic resonance imaging apparatus according to the embodiment comprises an acquisition unit, a generation unit, a calculation unit, and a determination unit. The acquisition unit performs a first MR imaging on a subject to acquire k-space data. The generation unit generates morphological image data representing the morphology of the subject based on the k-space data. The calculation unit calculates phase distribution data representing the spatial distribution including phase information, based on at least the morphological image data. The determination unit determines, based on the phase distribution data, whether or not a change is necessary for a second MR imaging that follows the first MR imaging.

The invention relates to a method of MR imaging of a body (10) of a patient located in an examination volume of an MR device (1). It is an object of the invention to provide a method which enables a geometrically corrected MR-only radiotherapy planning with a minimum number of scans. The method of the invention comprises the following steps: acquiring first MR imaging data representing at least one region of the body (10); analyzing the first MR imaging data to delineate at least one anatomical structure within the body region; acquiring second MR imaging data of the body region using a multi-point Dixon sequence; deriving a B0 map from the second MR imaging data; analyzing the B0 map to determine at least one low-fidelity region of the B0 map; performing a B0 mapping using a multi-shot gradient echo sequence limited to at least one region which fully or partially overlaps with the delineated anatomical structure and the low-fidelity region to refine the B0 map; and, correcting geometric distortions in the first and / or second MR imaging data using the refined B0 map. Furthermore, the invention relates to an MR device (1) for performing the method and to a computer program to be executed on an MR device (1).

A method for medical imaging includes performing a single-modality scan of a subject using a single-modality imaging device to acquire sparse measurements, wherein the single-modality is either computed tomography (CT) or magnetic resonance imaging (MRI); and simultaneously reconstructing both CT and MR image pairs from the sparse single-modality measurements using a multi-layer perceptron (MLP) neural network; wherein initial weights of the MLP are learned from a pair of pre-treatment CT and MR images of the subject.

Examples of the presently disclosed technology provide new systems and methods for real-time temperature propagation and tissue damage visualization during laser interstitial thermal therapy (LITT) procedures that do not rely on real-time MR imaging. Accordingly, examples enable performance of LITT procedures in regular operating rooms lacking MR-equipment—thereby reducing costs and improving availability for LITT procedures. Examples achieve these advantages by leveraging “discretized” patient-specific 3D brain structure representations to perform numerical methods for solving partial differential equations that estimate real-time (or close to real-time) temperature propagation within a patient's brain during a LITT procedure.

Systems and methods for image reconstruction for parallel MR imaging are disclosed that receive a k-space single-coil measurement dataset that includes at least two k-space single-coil measurement sets, transforming the k-space single-coil measurement dataset to an estimated CSM using a coil sensitivity estimation module, and transforming the k-space single-coil measurement dataset and the estimated CSM into a final MR image using an MRI reconstruction module. In some aspects, the coil sensitivity estimation module and MRI reconstruction module include deep learning neural networks trained without the use of ground truth data.

A method of controlling a magnetic resonance (MR) imaging system includes: receiving a diffusion tensor imaging (DTI) command, the command including a number of gradient vectors; obtaining a set of gradient vectors according to the number in the command, by: (i) selecting an initial set of gradient vectors; (ii) adjusting each gradient vector in the set, to generate a set of adjusted gradient vectors; (iii) determining a cost function based on the set of adjusted gradient vectors, the cost function indicating an impact of the set of adjusted gradient vectors on diffusion tensor variance; (iv) repeating the selecting, the adjusting, and the determining until an optimization condition is met, to obtain a final set of gradient vectors; and controlling the MR imaging system to capture a set of images based on the final set of gradient vectors.

The invention relates to a method of MR imaging of an object, namely of at least a part of the female breast. The method of the invention comprises the steps of: a) subjecting the object (10) to an imaging sequence comprising RF excitation pulses and switched magnetic field gradients, wherein multiple echo signals are generated at different echo times (TE1, TE2, TE3) after each RF excitation pulse, b) acquiring the echo signals along a set of radial or spiral k-space trajectories covering a given k-space region, wherein each of the echo signals generated after an RF excitation pulse is assigned a different orientation of the radial or spiral trajectory in k-space; c) reconstructing a single echo image for each echo time (TE1, TE2, TE3) from the echo signals acquired; d) deriving high-resolution water, fat, B0 and / or apparent transverse relaxation time (T2*) maps from the single echo images using a deep learning algorithm; and d) synthesizing a high-resolution mammogram from the water, fat, B0 and / or T2* maps. Moreover, the invention relates to an MR device (1) and to a computer program for an MR device (1).

A single or multiple self-tuning coil element for an MR imaging system is provided. The element is flexible and stretchable and may conform to various body parts and patient sizes. The element may be worn by the patient during the MR imaging session. Each coil may have one or more interdigital capacitors formed of flexible conductive traces. The capacitance of the interdigital capacitor(s) changes under stretching which provides the self-tuning. The traces may be made of liquid metal. The liquid metal may be doped with a contrast agent such that the coil is substantially invisible on an MR image. The coil(s) in a multiple coil element may be arranged in a single or a dual layer.

A phantom for use with an MR imaging device, such as a clinical or pre-clinical MR imaging device, the phantom includes: a sealable tube sized to fit within the imaging device; at least one fiber bundle removably inserted within the sealable tube, each of the at least one fiber bundles comprising a plurality of fibers; and a matrix material contained within the sealable tube and surrounding the at least one fiber bundle inside the sealable tube, the matrix material being an aqueous fluid and mimicking biological tissue or fluid properties. One or more characteristics of the at least one fiber bundle and / or the matrix material are selected to evaluate imaging characteristics of the MR imaging device and / or to conduct an imaging study.

The embodiment of the present application discloses a method and device for limiting radio frequency alternating magnetic field in magnetic resonance imaging. The method comprises: obtaining a first B1 field intensity required when a local coil surface temperature reaches a maximum safe temperature in a thermal equilibrium state when the local coil is placed at a set position in a detection hole of an MR scanner; obtaining a second B1 field intensity required for heating the local coil surface temperature to the maximum safe temperature within a set MR total scanning time when the local coil is placed at the set position according to a relationship among the local coil surface temperature, the scanning time and the B1 field intensity during MR scanning and the first B1 field intensity; and determining a third B1 field intensity required for MR scanning using the set MR total scanning time according to the second B1 field intensity. The embodiment of the present application reduces waste of B1 field performance while ensuring patient safety and improving MR imaging quality.

The present invention relates to sedation assessment. To facilitate sedation depth monitoring in a self-imaging environment, it is proposed to use the imaging modality itself to measure responses to appropriate reflexes, including but not limited to the pupillary reflex, the so-called superficial reflexes, and the withdrawal reflex, to determine sedation depth. In one embodiment, the pupillary reflex can be measured in an MRI system by dedicated iris MR imaging interleaved with the regular scanning protocol. In another embodiment, the superficial reflexes in response to touching the skin can be measured. This can involve a dedicated actuator that can be tightly integrated with the imaging modality, for example an MR receive coil applied to the patient. Alternatively, a remote haptic system can also be used. The reflex is then acquired with appropriate diagnostic imaging methods. In another embodiment, the withdrawal reflex in response to pain can be measured. This can involve an actuator that induces sudden suture pain or very localized temperature-induced pain and is tightly integrated with the imaging modality, for example a pinch device integrated with the patient support or an MR receive coil applied to the patient. The reflex is then acquired with appropriate diagnostic imaging methods.

The invention relates to a Mn (II)-TA network coated berberine-loaded nano-composite and a preparation method and application thereof.The nano-composite comprises a network on the outer layer and loaded particles on the inner layer, the network is formed by divalent manganese ions and tannic acid, the loaded particles are polypyrrole particles stabilized by mPEG modified hyperbranched polyethyleneimine particles, the diameter of the loaded particles is 1-10 micrometers, and the diameter of the loaded particles is 1-10 micrometers. And berberine is wrapped in hydrophobic cavities of the hyperbranched polyethyleneimine particles. The preparation process of the prepared nanocomposite is simple and convenient, the experimental steps are easy to operate, the reaction condition is normal pressure, and the method has obvious operation advantages. The prepared nanocomposite can support MR imaging of cancer cells, and can be used for CDT / PTT / CM combined treatment of cancer cells under the guidance of MR imaging.

The invention relates to a method of MR imaging which addresses the interplay of patient-induced artifacts, operational complexity, and the need for precise imaging of clinically relevant areas. The method comprises: acquiring MR imaging data from a patient's anatomy by executing at least one (pre-) scan to generate an image of the anatomy and to extract information including at least one of coil sensitivity distribution, B0 field distribution, B1 field distribution, spatial distribution of flow characteristics, spatial distribution of motion characteristics; identifying an anatomic structure or region of interest within the imaged anatomy; automatically adapting settings of an MR scanner used and / or parameters of an MR imaging sequence or protocol taking the extracted information into account for enhancing image quality or diagnostic utility for the identified anatomic structure or region of interest; and acquiring further MR imaging data from the patient's anatomy using the MR imaging sequence or protocol with the adapted settings and / or parameters to generate one or more optimized images of the identified anatomic structure or region of interest. Moreover, the invention relates to an MR imaging system and to a computer program.

For reconstruction in sampling-based imaging, such as reconstruction in MR imaging, an iterative, multiple-mapping based hierarchal machine-learned network reconstruction may produce artifact corrected images based on under-sampled scans. Two or more mappings may be used to reduce the presence of artifacts, in some cases including localized low-noise-contribution artifacts, relative to reconstructions based on fully-sampled scans.