68 results about "Positron" patented technology

The invention belongs to the technical field of vacuum coating, and relates to an electron gun and ion source collaborative evaporation coating method, a control method and a control system. The electronic gun and ion source collaborative evaporation coating control method comprises the steps that key parameters in the coating process are continuously collected, and an electronic gun beam initial value and an ion source gas flow initial value are dynamically generated according to state diagnosis results of all the parameters; the beam current value of the electron gun and the gas flow value of the ion source are corrected in real time to inhibit the disturbance of the ion source to the beam current of the electron gun, and the electron gun and the ion source are cooperatively regulated and controlled to ensure the precise control of the coating uniformity; the invention further discloses an electron gun and ion source collaborative evaporation coating method, local hot spot compensation and global uniformity compensation are carried out by adopting a film thickness compensation mechanism so as to accurately control the film thickness. According to the invention, the cooperative control of the electron gun evaporation and ion bombardment process is realized, the film adhesion is enhanced, the evaporation coating rate is improved, and the film thickness uniformity is improved.

A multiplexing scheme for both energy and timing information is provided for a particle detection system having a photosensor array with multiple photosensors. Each photosensor is associated with multiple scintillator modules. The system has a segmented pseudo-prismatic light guide with multiple pseudo-prismatic segments. Each segment is associated with multiple photosensors, and the photosensors are adjacent. Each scintillator module contacts its associated photosensor at one end and its associated segment at the other end. Each of the multiple photosensors may be connected to an energy readout channel, such that photosensors associated with the same segment are not connected to the same energy readout channel. Each energy readout channel has at least two timestamps associated therewith.

This invention relates to a convolution-based method for noise suppression in positron emission tomography (PET) flow field images, comprising the following steps: S1, obtaining consistent data through CFD flow field simulation and GATE detection system simulation, and reconstructing a low-resolution initial image of the PET flow field containing noise using the OSEM algorithm; S2, constructing a noise suppressor model, inputting the low-resolution initial image into the model, and outputting a noise-suppressed flow field feature image using a deep convolutional network and multi-scale feature fusion technology; S3, constructing a multi-loss fusion evaluation system, using mean squared error loss, minimum absolute value deviation loss, and perceptual loss to jointly constrain model training, and iteratively updating the weights using the Adam optimizer. This invention not only improves the enhancement model's ability to distinguish noise information, thereby enhancing the model's ability to remove noise information from PET images, but also significantly improves evaluation metrics such as PSNR and SSIM.

The invention belongs to the technical field of inorganic scintillator materials, and particularly relates to a multi-element co-doped yttrium lutetium silicate scintillator and a preparation method and application thereof, and the material has excellent comprehensive performance of high light output, short decay time, high radiation hardness, high matching degree of emission spectrum and novel photoelectric sensors and the like. The invention further relates to a preparation method of the scintillator material and application of the scintillator material in radiation detection fields such as positron emission tomography (PET), time flight PET (TOF-PET), interaction depth PET (DOI-PET), single photon emission computed tomography (SPECT), high-energy physical experiments, nuclear medicine imaging, industrial nondestructive inspection, safety detection (such as luggage and cargo container inspection) and the like.

The present disclosure provides a modular radiation therapy apparatus comprising a plurality of modules configured to sequentially interlock within one another in an annular arrangement, wherein the plurality of modules are individually extractable from the annular arrangement and at least a subset of the plurality of modules comprise computing elements configured to communicate with one another, the plurality of modules comprising a collimator module comprising a multi-leaf collimator (MLC) and at least one sensor, a linear accelerator (LINAC) module comprising at least one of a magnetron or a klystron, at least one imaging module comprising at least one of an image detector, an imaging source, a magnetic imaging system, a single photon emission computed tomography (SPECT) system, or a positron emission tomography (PET) system, a patient tracking module, a cooling module, and a vacuum module, and performing at least one of: monitoring a respective status of the plurality of modules via onboard sensors and computing elements to determine whether any module is in an error state and provisioning status information and module identifiers to a remote computing environment; or distributing computational workloads among the plurality of modules and communicating with a remote computing environment to offload processing tasks using federated processing operations.

The invention belongs to the technical field of PET (positron emission tomography), and relates to a PET probe extensive field image multi-model adaptive deformation and FPGA (field programmable gate array) curing method, which comprises the following steps of: acquiring single-lift event data of a PET probe; generating an original extensive field image based on the single-lift event data; performing coordinate traversal transformation on the original extensive field images by adopting an image deformation model in a preset multi-model transformation library; performing off-line analysis on each model and the parameters thereof in the multi-model transformation library by utilizing a preset evaluation index, and screening out an optimal model and an optimal parameter; and transforming the original pan-field image by using the optimal model and the optimal parameters to generate an enhanced image and a crystal position lookup table, and solidifying the enhanced image and the crystal position lookup table to the FPGA. The method has the beneficial effects that the local adhesion area can be stretched in a targeted manner through the nonlinear transformation model, the distinction degree of crystal event clusters is remarkably improved, and the LUT calibration precision is fundamentally improved.

A method for determining a convolution kernel for an iterative statistical algorithm based on a continuous-to-continuous data model. The method is used for image reconstruction from radiation measurements obtained in emission tomography, specifically in a Time-of-Flight Positron Emission Tomography (TOF PET) scanner. The presented method is a non-list-mode solution that reduces the computational complexity of the reconstruction problem, improves the resolution of reconstructed images, reduces the radiation dose absorbed by patients during TOF PET examinations, and / or shortens the measurement acquisition time without significantly compromising the quality of the diagnostic images. Notably, the quality of the functional images remains at the same level. These improvements are achieved by designing the convolution kernel to account for the statistical properties of the measurement signals registered during the TOF PET scanner's acquisition process.

To provide both good time-of-flight resolution and interaction depth information. [Solution] The positron emission tomography apparatus according to the embodiment comprises a scintillation array and a photosensor array. The scintillation array includes a plurality of scintillator crystal units individually separated by a reflective material, and each scintillator crystal unit is configured to generate scintillation light in response to gamma-ray interactions within the scintillator crystal unit caused by gamma-ray irradiation from a subject, and has a substructure for decoding two or more depths within the scintillator crystal unit such that gamma-ray interactions at different depths cause scintillation light to escape from the photo-escape plane of the scintillator crystal unit in different patterns. The photosensor array converts the scintillation light received from the scintillation array into an electrical signal.

An image acquisition apparatus includes a measurement unit and a processing unit. The processing unit, for each coincidence event in which a first detector and a second detector perform coincidence detection of a pair of gamma-ray photons generated by an electron positron annihilation event in a positron emitting radionuclide, assuming that the gamma-ray photon arriving at one detector is a gamma-ray photon arriving without being Compton scattered in a subject, and the gamma-ray photon arriving at another detector is a gamma-ray photon arriving after being Compton scattered in the subject, determines a position at which the gamma-ray photon is Compton scattered in the subject based on a detection position and a detection time of the gamma-ray photon by each of the first detector and the second detector and a position of the positron emitting radionuclide.

The application provides a simulation prediction method and system for slow positron source intensity in a research reactor, comprising the following steps: S1, reading arrangement information of components in a reactor core of the research reactor; S2, constructing a Monte Carlo model of the reactor core containing a slow positron source device, and obtaining neutron multi-group angular flux and photon multi-group angular flux information near the slow positron source generating device; S3, constructing a slow positron Monte Carlo model; S4, performing energy-angle double sampling to obtain an incident neutron energy probability density distribution function f n,ig,ia , an angle probability density distribution function f n,ia , an incident photon flux energy probability density distribution function f g,ig,ia , an angle probability density distribution function f g,ia , and a neutron-photon weight factor; S5, performing function sampling of particle types, energy and angle; and S6, obtaining slow positron distribution information generated in the slow positron generating device. The application accurately considers the whole life cycle of slow positron generation and transportation through multi-stage coupling, and realizes accurate prediction of slow positron source intensity.

The present invention facilitates manufacturing of a scintillator array, a radiation detection device, and a positron emission tomography device. A scintillator array (11) is provided with at least one pair of scintillators (11Uia, 11Uib), a light reflection member (LA) disposed in a first location between the scintillators for preventing light from passing between the scintillators, and an air layer (LB) disposed in a second location between the scintillators for allowing light to pass between the scintillators.

The utility model discloses purification column equipment for positron radiopharmaceutical purification, which belongs to the technical field of pharmaceutical purification, and adopts the technical scheme that the purification column equipment comprises a column tube body, the bottom of the column tube body is fixedly connected with a supporting mechanism, and the surface of the supporting mechanism is connected with a splitting mechanism in a sliding manner; the top of the column pipe body is movably connected with a pipe cover, the top of the pipe cover is fixedly connected with a filling pipe, the bottom of the column pipe body is fixedly connected with a liquid outlet pipe, and a supporting mechanism limiting ring is fixedly connected to the bottom of the inner side of the column pipe body and provides a basic supporting point for the whole supporting structure. A limiting rod penetrates through a limiting block, is fixed at the top of a limiting ring and is matched with a sieve plate and a connecting hole in the limiting block, so that precise guidance is provided for sliding of the sieve plate, the sieve plate can only move in the direction of the limiting rod, and the separation efficiency is improved. The operation accuracy of the splitting mechanism is ensured, and the splitting mechanism is provided with three sieve plates.

Compounds and their use for imaging a disease, condition, or disorder associated with one or more Complement system pathways are disclosed.

The purpose of this beam source is to develop a positron microbeam, making it the first attempt to describe e + As a beam / current for pumping / injecting semiconductor devices. Furthermore, Type I: Positron beams possess high energy (up to hundreds of keV or even tens of MeV), but their range should follow the same limits as electrons, since electrons can be converted into positrons, both of which can be used as sources for pumping materials. This will prevent the formation of defects in positron-pumped materials, which would otherwise cause rapid degradation of material properties. Type II: The conversion to Weyl fermions, which are thought to carry charge through devices much faster than ordinary electrons. According to recent research, Weyl electrons carry current at least twice as fast as graphene electrons and at least 1000 times faster than electrons in ordinary semiconductors. This patent aims to advance research in this field by utilizing Weyl electrons as a beam / current for pumping / injecting semiconductor devices.

Systems, methods, and devices provide data correction for positron emission tomography (PET) examinations using an external, supplemental radioactive source. The supplemental radioactive source is formed of a uniformly distributed radionuclide. The uniformly distributed radionuclide is positioned in a support structure which is positioned into an inner bore of a PET scanner and secured in place by a friction fit, or directly integrated into the PET system. A transmission source control system moves the one or more 2024 / 059537 transmission sources into the support structure for performing the PET examination (e.g., using a hydraulic system). The transmission source control system also retracts the one or more transmission sources back into a source storage device upon completing the PET examination. Various data correction algorithms use the first PET signal data, originating from a radiotracer injected in the patient, and second PET signal data, originating from the uniformly distributed radionuclide.

The invention belongs to the technical field of positron emission tomography, and relates to a PET probe extensive field image dot matrix self-adaptive recognition and anomaly detection method, which comprises the following steps: acquiring an original extensive field image of a PET probe and preprocessing the original extensive field image; performing global projection and peak searching based on the pre-processed extensive field image, and counting the number of projection peak values; judging whether the number of the projection peak values accords with expectation or not; on the basis of the number of projection peak values conforming to expectation, performing global adaptive grid division on the preprocessed image to obtain a plurality of sub-image regions; performing local bidirectional projection and Gaussian fitting on each sub-image area, and determining a positioning coordinate set of each point in the crystal array; and based on the positioning coordinate set, performing anomaly detection to generate a quality inspection report. The method has the beneficial effects that the adaptability is high, the method does not depend on a prior template, an accurate geometric template does not need to be provided during image quality screening, the dot matrix scale is automatically estimated by analyzing extensive field image data, and the universality and deployment convenience of the method are improved.

A positron emission tomography (PET)-scanning device is provided, having a detector ring for detecting emitted PET-radiation and a main supporting structure which has or to which is attached a U-shaped portion with two arms for holding the detector ring between the arms. The detector ring is held by the two arms in such a way that the detector ring can be rotated about an axis of rotation that extends through the U-shaped portion, in particular through the two arms of the U-shaped portion.

The present disclosure is related to systems and methods for data masking. The method includes obtaining data associated with coincidence events related to intrinsic background radiations of a plurality of crystals of the PET device. Each of the coincidence events may be detected by two crystals of the plurality of crystals of the PET device. The data associated with the each coincidence event may include first time information and second time information. The method includes determining a first time of fight (TOF) difference corresponding to the each coincidence event based on the first time information and the second time information. The method includes determining a second TOF difference corresponding to the each coincidence event based on locations of the two crystals that detect the each coincidence event. The method includes correcting the PET device based on the first TOF difference and the second TOF difference.

The disclosure describes a vehicle propulsion system that uses antimatter stored in a chamber stabilized by magnetic and / or electrostatic fields. The antimatter chamber is positioned at a distance from the vehicle's center of gravity to create a matter-antimatter dipole that generates propulsion. The system includes a propulsion apparatus with a laser that produces photons and an optical device that spatially separates some of the photons into electrons and positrons using nonlinear optical effects. These particles are coupled into separate optical fiber coils that preserve photon coherence as they propagate. The coils are arranged to be spaced apart or partially overlapping so that the separated electrons and positrons form a matter-antimatter dipole, which produces a propulsion force that drives the vehicle.

Embodiments of the present disclosure provide compositions comprising compounds useful to make radiotracers for positron emission tomography imaging, as well as methods for making and using these compositions.

An image acquisition device (1A) is provided with a measurement unit (10) and a processing unit (20). For each coincidence counting event, that is, an event in which a pair of gamma-ray photons generated by an electron-positron pair annihilation event in a positron emission nuclide (81) is counted simultaneously by a first detector (11) and a second detector (12), a processing unit (20) has gamma-ray photons arriving at the second detector (12) after Compton scattering occurs within a subject (90). When the signal output by the first detector (11) and the signal output by the second detector (12) are lower than a first threshold value lower than 511 keV, the position of the positron emission nuclide (81) is detected selectively on the basis of the detection position and the detection time of the gamma ray photons and the position of the positron emission nuclide (81), respectively, detected by the first detector (11) and the second detector (12), and the position of the positron emission nuclide (81) is lower than a first threshold value lower than 511 keV. The position at which Compton scattering occurs in the subject (90) of the gamma ray photons is determined. This realizes an image acquisition device and an image acquisition method that can acquire a tomographic image representing anatomical information of a subject without performing image reconstruction processing.

The invention relates to the technical field of nuclear radiation detectors and positron emission tomography (PET) imaging, and discloses a PET detector, a depth positioning method based on the PET detector and a storage medium. The PET detector is composed of a photoelectric detection element array, a crystal array composed of N * M scintillation crystals, a reflecting material and a transparent optical material. The crystal array includes a first end and a second end, and at least one of N and M is greater than 1, at least one of N and M is an odd number, and the first end is coupled to the array of photodetection elements. A reflective material and a transparent optical material are added in gaps between the plurality of scintillation crystals of the crystal array so as to divide the first end into a plurality of first regions to form a first shared optical path and divide the second end into a plurality of second regions to form a second shared optical path. A target first region of the plurality of first regions and a target second region of the plurality of second regions each include a central crystal in the crystal array. And the multiplexing of the scintillation photons is realized through the shared light path.

The invention relates to a radiation source generation method and device, a correction method and device and a storage medium. The method comprises the following steps: outputting an idle beam current in a set time period by using beam current generation equipment; an activated target material capable of generating positron nuclide is generated in situ through bombardment of the target material by the idle beam current; and preparing the activated target material into a correction source in a required form according to the physical state of the target material. According to the invention, the beam generation equipment is used for preparing nuclides used for correction, the beams are taken from idle resources of existing equipment, the problems of approval process, transportation time efficiency and cost of outsourcing radioactive sources are avoided, the defect that the sources cannot be obtained in time under sudden calibration requirements is solved, the existing idle beam resources can be reused, resource waste is avoided, and the calibration efficiency is improved. Correction sources in corresponding forms can be prepared according to requirements.

A method for determining a convolution kernel for an iterative statistical algorithm based on a continuous-to-continuous data model for image reconstruction from radiation measurements obtained in emission tomography, specifically in a Positron Emission Tomography (PET) scanner. The method improves the resolution of reconstructed images, reduces the radiation dose absorbed by patients during PET examinations, and / or shortens the measurement acquisition time without significant loss in the quality of the diagnostic images obtained. Specifically, the quality of the functional images remains at the same level. These improvements are achieved through the design of the convolution kernel, which takes into account the statistical properties of the measurement signals registered during the acquisition process in the PET scanner.

Positron emission tomography (PET) radiotracers for imaging macrophage colony-stimulating factor-1 receptors in subjects suffering from or suspected of suffering from a neuroinflammatory or neurodegenerative disease or disorder are disclosed.

This invention provides a dose prediction system, dose prediction method, and dose prediction program for accurately evaluating particle beam irradiation doses and supporting treatment using particle beams. [Solution] The support device 20 comprises an irradiation device 31 that irradiates with a particle beam, a detection device 32 that measures the irradiation area of ​​the particle beam, an imaging device 33 that photographs the light emission of the irradiation area, and a control unit 21 that predicts the irradiation dose by the irradiation device 31. The control unit 21 acquires the light emission distribution of the surface of the irradiated object irradiated with the particle beam, acquires the activity distribution of positron emission nuclei generated on the side surface of the irradiated object, and calculates a three-dimensional dose distribution using the light emission distribution and the activity distribution.

Systems and methods for estimating mean randomness include: acquiring list pattern data describing true and delayed coincidences detected by a positron emission tomography (PET) scanner during a scan of an object; determining, based on the list pattern data, delayed coincidences including said crystals for each crystal of the PET scanner and for each of a plurality of time periods of the scan; for each crystal, determining a single event rate associated with each time period based on the delayed coincidences determined for the crystal within the time period; for each time period, determining an estimated mean randomness for each of a plurality of crystal pairs based on the single event rate associated with the time period for each crystal of the crystal pair; and reconstructing an image of the object based on the estimated mean randomness for each time period and the detected true coincidences.

A Positron Emission Tomography (PET) apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to determine a virtual detector region on the basis of a Positron Emission Tomography (PET) detector capable of detecting, in a real number coordinate system, a light emission position of an event occurring due to pair annihilation gamma rays becoming incident, a Line Of Response (LOR) defined based on the event detected by the PET detector, and the light emission position and is configured to perform a reconstruction process on the basis of the virtual detector region.

The invention relates to the technical field of particle physical detection and high-energy density physical diagnosis, in particular to an electron positron ion spectrometer, which comprises a collimation unit, an aiming unit and a shell, and is characterized in that a magnetic field dispersion unit, an electric field separation unit and a detection unit are arranged in the shell; a magnetic field area is formed on one side, opposite to the collimation unit, of the magnetic field dispersion unit so as to perform energy expansion on incident charged particles along a first direction; the electric field separation unit is orthogonally arranged with the first direction and distinguishes particle types along the second direction; the detection unit adopts a curved surface structure conformal with dispersion geometry, so that particles are incident approximately vertically and aberration is suppressed, and a two-dimensional pattern representing energy in an arc length direction and representing particle types in an arc height direction is obtained. Through the synergistic effect of the magnetic field dispersion unit and the electric field separation unit, clear spatial separation of positive electrons, protons and electrons in a wide energy region can be realized; and the detection unit adopts a curved surface structure conformal with dispersion geometry, so that the accuracy of wide-energy-region energy spectrum data can be ensured.