8 results about "Cherenkov radiation" patented technology

The current disclosure provides systems and methods for increasing a quality of positron emission tomography (PET) images generated by a PET system with detectors including bismuth germinate (BGO) crystals. In one example, a method for the PET system comprises extracting a higher-quality 2-D image from a first image volume reconstructed using higher-quality time-of-flight (TOF) data acquired from a subject during a scan performed using the PET system, the TOF data based on Cherenkov radiation detected at the BGO crystals; extracting a lower-quality 2-D image from a second image volume reconstructed using lower-quality TOF data acquired from the subject by the PET system; generating an enhanced-quality 2-D image from the lower-quality 2-D image using a trained image quality enhancement model; merging the enhanced-quality 2-D image with the higher-quality 2-D image; and displaying the merged 2-D image on a display device of the PET system.

This invention discloses a time-of-flight detector based on Cherenkov radiation detection and its fabrication method. The detector includes a Cherenkov radiator, with a photocathode coated on the light-emitting surface of the radiator, and an anode array-type photoconverter located behind the photocathode. The Cherenkov radiator is a two-dimensional array structure, wherein low-refractive-index transparent optical material layers are respectively disposed on the opposite sides of adjacent array units, and high-reflectivity material is filled between the low-reflectivity transparent optical material layers. One end of the two-dimensional array structure is the incident light surface, and the other end is the light-emitting light surface. The Cherenkov radiator interacts with the incident radiation to generate Cherenkov photons and confines them in the corresponding array units for transmission to the photocathode. The photocathode converts the input Cherenkov light into photoelectrons and inputs them to the anode array-type photoconverter. The anode array-type photoconverter amplifies the input photoelectrons and outputs them. This invention improves the number of detected photons and the position resolution capability.

The application discloses an ultrahigh-power Cherenkov radiation generator, and solves the problems of low output power, low conversion efficiency and narrow frequency modulation range of a current frequency modulation waveform generated by a relativistic backward wave tube, and specifically comprises a ring cathode, a coaxial reflector, a non-uniform slow wave structure, a uniform slow wave structure, a coaxial coupling structure and a magnetic field coil which are coaxially connected in sequence at the back side of the ring cathode; the non-uniform slow wave structure and the uniform slow wave structure are both overmoded structures, compared with a single-mode structure, the device power capacity is improved, and meanwhile, the device can work at a higher working voltage, which is beneficial to generating ultrahigh power.

Systems and methods verify position of deformable tissue undergoing radiotherapy using Cherenkov radiation. A Cherenkov image is captured of a treatment area of a subject during the radiotherapy. The Cherenkov image is segmented to generate a bio-morphological feature image defining vasculature of the deformable tissue. A transfer learning strategy is used to train a convolutional neural network to segment the Cherenkov image. A rigid registration of the bio-morphological feature image and a reference image is performed to determine a rigid displacement. A non-rigid registration of the bio-morphological feature image and the reference image is performed to determine a deformation map indicating locoregional deformation of the deformable tissue. A repositioning alert is generated when the locoregional deformation is greater than a deformation threshold, and an abort alert is generated when registration of the bio-morphological feature image and a reference image us unsuccessful.

Beam calibration instrument and method are provided to calibrate radiotherapy beams (including but not limited to the FRASH-RT beams) used in radiotherapy oncology treatment programs based on the detection of Cherenkov light generated in a plastic material. The calibration instrument may comprise a monitor body and a radiation beam source configured to emit a beam into the monitor body. The beam is configured to interact with a material of monitor body to release Cherenkov radiation within the monitor body. The calibration instrument further includes a detector configured to detect the Cherenkov radiation, and a detection system configured to determining a characteristic associated with the calibration beam. The detector is coupled to the monitor body.

The invention discloses a SiPM array-based deuterium-tritium fusion power diagnosis spectrometer and a measurement method thereof. The diagnosis spectrometer comprises a cylinder body; the conversion target, the light-transmitting layer and the SiPM array are sequentially arranged on the cylinder body at intervals; a radiator filled between the conversion target and the light-transmitting layer; the SiPM array comprises a plurality of silicon photomultipliers, and the plurality of silicon photomultipliers are distributed in an array and form an annular array; the conversion target is configured to generate electrons when irradiated by gamma rays formed by fusion, and the irradiation position of the gamma rays corresponds to the ring hole position of the annular array; the radiator is configured to generate Cherenkov radiation under the action of electrons; the silicon photomultiplier is configured to detect the Cherenkov radiation, and the backlash electron scattering angle is determined according to the position information of the silicon photomultiplier which detects the Cherenkov radiation, so that the energy of the gamma ray is determined, and the measurement accuracy is high.

A multistage depressed collector (MSDC) 200 is disclosed for recovering energy from an electron beam 204 in, for example, an electromagnetic power source generating stimulated Cherenkov radiation. The

This invention provides a radioactive Cherenkov photoactivated intelligent therapeutic nanosensor, its preparation method, and its application, belonging to the field of biomaterials preparation technology. This invention achieves precise matching between the Cherenkov radiation spectrum and the absorption peak of a photosensitizer by constructing an intelligent therapeutic nanosensor, and establishes a dual-response release mechanism in the tumor microenvironment, realizing precise drug release under the synergistic triggering of acidic pH and overexpressed hydrogen sulfide. This invention utilizes the CR self-excitation effect to emit light in normal tissues, while simultaneously quenching fluorescence within the tumor where hydrogen sulfide is overexpressed, thereby achieving dual-locked Cherenkov radiation-mediated photodynamic therapy in the tumor microenvironment. The intelligent therapeutic nanosensor of this invention achieves the transformation from fluorescence emission in normal tissues to tumor-specific activated CR-PDT by forming deep hole trap energy levels, demonstrating excellent practicality.