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545 results about "Fluorescent light" patented technology

Simply put, fluorescent lighting is a kind of lighting technology which depends on a chemical reaction inside of a glass tube to create light. This chemical reaction involves gases and mercury vapor interacting, which produces an invisible UV light.

Systems and methods for high-throughput, multi-well spatiotemporal illumination microscopy

PCT designated stage expiredWO2025106923A1MicroscopesFluorescence/phosphorescenceRadiologyImaging lens
A spatiotemporal illumination microscope system is presented. The system includes a multi-well plate configured to receive live cells and a DMD configured to deliver targeted illumination to selectively illuminate a plurality of the wells. The system further includes a tandem-lens system having an objective lens and an imaging lens positioned facing each other to capture fluorescent light emitted from the cells. The system also includes an image sensor that receives fluorescent light captured by the tandem-lens system, generating imaging data. The system further includes a controller configured to use the imaging data to control closed-loop modulation of the live cells.
Owner:RGT UNIV OF CALIFORNIA

Detection and localization of disease utilizing fluorescence spectra of exogenous fluorophores

The present discloses systems and methods for tissue analysis, biopsy, and treatment utilizing at least exogenous fluorophores and near infrared light. A method is disclosed for optically determining the presence of abnormal cells, such as cancer, in tissue. The method includes applying one or more exogenous fluorophores into tissue in an animal body, wherein the exogenous fluorophores include a targeting moiety formulated to bond with a selected site on abnormal cells. The method includes illuminating the one or more exogenous fluorophores in the tissue with near infrared light from an elongated optical probe to generate fluorescent light from exogenous fluorophores present in the tissue. The method includes receiving fluorescent light generated from the one or more exogenous fluorophores in the tissue. The method includes determining if abnormal cells are present in the tissue based on the fluorescent light generated from the one or more exogenous fluorophores in the tissue.
Owner:PREVIEW MEDICAL INC +1

Exterior mirror system and method for fluorescence imaging

ActiveCN119606317Aimprove clarityHave tumor fluorescence informationDiagnostics using fluorescence emissionSensorsRemoval tumorImaging processing
The invention relates to an exterior mirror system and method for fluorescence imaging, and relates to the technical field of image processing, the system can detect fluorescence under a white light operation condition in a tumor excision process, and imaging in a dark or dim operating room is not needed; white light in the fluorescent light is separated, so that a clear fluorescent light image is presented; in addition, fluorescence images can be displayed in a 3D mode, and development is more visual. According to the invention, the technical problems of dark fluorescence image, poor definition and complicated operation in the developing process in the prior art are solved.
Owner:ZHEJIANG HEALNOC TECH CO LTD

Light-emitting super-structure surface capable of realizing incoherent fluorescent holography and multi-dimensional super-structure display and preparation method of light-emitting super-structure surface

The invention discloses a light-emitting super-structure surface capable of realizing incoherent fluorescence holography and multi-dimensional super-structure display and a preparation method thereof. The light-emitting super-structure surface is mainly composed of an optical waveguide structure layer, a micro-nano structure layer and a fluorescence emission layer. The optical waveguide structure layer comprises a substrate and a waveguide layer and is responsible for guiding fluorescence propagation; the micro-nano structure layer is located above the waveguide layer, is composed of nano bricks and can regulate and control light; the fluorescence emission layer is arranged above the micro-nano structure layer, contains quantum dots and is excited by the pump light to emit fluorescence. The metasurface can regulate and control the emergent angle, wavefront and emergent intensity of fluorescent light and pump light, the time-space coherence of the fluorescent light is enhanced through the waveguide layer, and phase modulation is carried out by using a method based on a circuitous phase. Based on the super-structure surface, through the steps of fluorescence excitation, coherence enhancement, phase modulation, diffraction calculation, hologram generation, multi-dimensional display and the like, incoherent fluorescence hologram and multi-dimensional super-structure display can be achieved, and the functions of fluorescence nanometer printing and multi-channel holographic display are covered.
Owner:WUHAN UNIV

Light source, optical device, related apparatus and method

The invention discloses a light source, an optical device, a related device and a method. The light source is used for emitting laser and fluorescence mixed light beams, and the optical device can be applied to the light source. The optical device can emit a fluorescent light beam under the excitation of the first laser beam in the light source, and can inhibit the speckle of the second laser beam in the light source, so that the light source can emit a fluorescent laser mixed light beam inhibiting the speckle, the number of devices in the light source can be reduced, and the volume of the projection light source can be reduced. And the market demand of miniaturization of the projector is met.
Owner:HUAWEI TECH CO LTD

Radiotherapy system, auxiliary system and method for evaluating free radical injury and application of auxiliary system and method

The invention discloses a radiotherapy system, an auxiliary system and method for evaluating free radical damage and application thereof, a tube body of a cuvette of the auxiliary system comprises side surfaces, a top surface and a bottom surface, the top surface is provided with an opening matched with a shading cover, and the side surfaces comprise a first side surface, a second side surface, a third side surface and a fourth side surface; one end of the first optical fiber is connected with the laser assembly, and the other end of the first optical fiber is connected with the first side surface; the irradiation assembly is arranged on one side of the top surface; the fluorescent light filter is arranged on the third side surface or the fourth side surface; one end of the second fiber is connected with the fluorescent filter, and the other end of the second fiber is connected with the luminosity assembly; the chamber is used for accommodating the cuvette and the fluorescent light filter; for FLASH radiotherapy, the real-time accurate detection of the fluorescence intensity can be realized by optimizing the detection environment, and a reliable platform is provided for free radical damage assessment.
Owner:MEVION MEDICAL EQUIPMENT CO LTD

Scanning structured light microscopic imaging system and method based on multi-focus diffraction-free light beams

PendingCN119439524AImproving Imaging EfficiencyImprove imaging depthMicroscopesMicro imagingSpatial light modulator
The invention relates to the technical field of optical microscopic imaging, and discloses a scanning structured light microscopic imaging system and method based on a multi-focus diffraction-free light beam. Exciting light emitted by a laser light source sequentially passes through an electro-optical modulator and a lens group I and then enters a spatial light modulator; the spatial light modulator is used for synchronously regulating and controlling the multi-focus array and the non-diffraction light beam to generate the multi-focus array with the non-diffraction light beam characteristic; afterwards, the light sequentially passes through a lens group II, a two-dimensional scanning galvanometer, a scanning lens, a tube lens, an emission optical filter, a double-color piece and an objective lens and then irradiates a sample to be imaged; fluorescent light generated by a to-be-imaged sample passes through the objective lens and the double-color sheet and then is transmitted to the area-array camera, and fluorescent light signals at a plurality of focal points are collected to form a fluorescent light image. According to the invention, a diffraction-free optical phase modulation mechanism is introduced, simultaneous imaging of different depth layers is realized, the imaging speed is improved, sample information missed due to limited focusing depth is avoided, and the optical power utilization rate and the imaging quality are greatly improved.
Owner:GUANGDONG UNIV OF SCI & TECH

Bright field and fluorescence integrated scanning equipment

The utility model relates to bright field and fluorescent light integrated scanning equipment, which comprises an equipment rack, a bright field light path assembly used for forming a bright field light path and a fluorescent light path assembly used for forming a fluorescent light path, the bright field light path assembly comprises a bright field camera, a light path pipe diameter, objective lens equipment, a slide holder for bearing a sample and a bright field light source module; the fluorescent light path assembly comprises a fluorescent camera, a light path pipe diameter shared by the fluorescent camera and the bright field light path, a fluorescent turntable, objective lens equipment, a slide holder and a fluorescent light source module; the bright field and fluorescence integrated scanning equipment is provided with a camera switching device; the objective lens equipment comprises a plurality of objective lenses with different multiplying powers, and the bright field light source module is provided with a diaphragm switching device for switching diaphragms based on the multiplying powers of the objective lenses; the slide holder is provided with a scanning motion module for moving the slide holder. According to the utility model, integration of bright field fluorescence is realized, the cost is reduced, and the system has the characteristics of better imaging effect and higher efficiency.
Owner:NINGBO SUNNY INSTR

Irradiation module and device and method for irradiation with medical and cosmetic radiation

The invention relates to an irradiation module for use in a device (1) for irradiation with medical and cosmetic radiation, comprising a plurality of LEDs arranged on a carrier. The invention also relates to a device for irradiating a user (10) with medical and cosmetic radiation, comprising a plurality of irradiation modules (40) for irradiation with medical and cosmetic radiation, which modules are accommodated in a housing part (20; 30). The invention further relates to a method for irradiating a user (10) with medical and cosmetic radiation, comprising a plurality of irradiation modules (40) for irradiation with medical and cosmetic radiation, which modules are selected from the group comprising fluorescent tubes, LEDs, organic LEDs, and high-pressure lamps. In order to provide an irradiation module and a device and a method with which improved irradiation results can be achieved according to the invention, a first group of first LEDs, which emits radiation within the UVA spectrum, and a second group of second LEDs, which emits radiation within the UVB spectrum, are arranged on the carrier.
Owner:JK HLDG

Microscope fluorescence optical filter switching device

The utility model discloses a microscope fluorescent light filter switching device, which relates to the technical field of biological experiment instruments and comprises a lens switching mechanism, a lens butt joint mechanism and a fluorescent light source assembly. A plurality of fluorescent light filters on the microscope body are arranged on the lens switching mechanism, and the lens switching mechanism is arranged between an eyepiece and an objective lens on the microscope body through the lens butt joint mechanism and the fluorescent light source assembly. The fluorescent light filter switching device is simple in structure and convenient to use, can rapidly switch a plurality of fluorescent light filters, effectively improves the efficiency and precision of fluorescent microscopic observation, reduces the risk of damage of the light filters, and is suitable for various fluorescent microscopic experiments.
Owner:THE FIRST AFFILIATED HOSPITAL OF HAINAN MEDICAL UNIV

Detection device and detection system

The invention provides a detection device and a detection system, and the detection device comprises a first light path seat which comprises a light source; the window seat is provided with a detection area; a first sensor that detects spectral information; the first sensor detects spectral information, the second sensor detects spectral information, the detection device is switched between a reference light path and a detection light path, in the reference light path, light rays enter the first sensor and the second sensor without entering the detection area, in the detection light path, the light rays enter the detection area, caused scattered light and fluorescence enter the first sensor, and in the detection light path, the light rays enter the second sensor. The detection area is provided with a first window sheet, a second window sheet and a third window sheet, the first window sheet is used for the light of a detection light path to penetrate through and enter the water in the detection area, and the second window sheet is used for the induced scattered light and fluorescent light to penetrate through and then enter the first sensor; and the third diaphragm is opposite to the first diaphragm, so that the light entering the detection area through the first diaphragm enters the second sensor.
Owner:CORE VISION (BEIJING) TECH CO LTD

Magnetic field sensor and method for calibrating the temperature of a magnetic field sensor

The invention relates to a magnetic field sensor (10), comprising: an excitation light source (6) for emitting excitation light (4), a measurement region (7) which has colour centres (3) in a crystal (1), preferably NV centres in a diamond, which emit fluorescent light (5) when excited with the excitation light (4), a detector (8) for detecting the fluorescent light (5) from the measurement region (7), a microwave emitter (11) for applying a microwave field (9) to the measurement region (7), a signal generator (14) which is designed to generate a microwave signal (15) for the microwave emitter (11) and has two frequency components (fsb-(t), fsb+,π(t)) phase-shifted in relation to one another by π, in order to simultaneously excite magnetic field resonances at two different resonant frequencies (f-, f+) in the crystal (1) in order to determine a magnetic field (B), and an evaluation device (12) which has a demodulator (13) for forming a demodulated magnetic resonance signal from the detected fluorescent light (5) of the measurement region (7), wherein the evaluation device (12) is designed to determine a detuning (∆B) of the resonant frequencies (f-, f+) due to a change in the magnetic field (B), and to generate a frequency shift (∆f) of the microwave signal (15) according to the magnetic-field-related detuning (∆B) of the resonant frequencies (f-, f+). The magnetic field sensor (10) is designed to determine, in a temperature calibration step, a temperature-related detuning (∆T) of the resonant frequencies (f-, f+) and to take same into account in the frequency shift (∆f) of the microwave signal (15) in order to determine the magnetic field (B). The invention further relates to an associated method for calibrating the temperature of a magnetic field sensor (10).
Owner:Q ANT GMBH

Three-dimensional modeling of interproximal spaces

PendingUS20250265798A1Image enhancementImpression capsInterproximal spaceDental instruments
Methods and apparatuses that may improve the accuracy of three-dimensional models from interproximal regions of intraoral scan data using non-structured light illumination images (e.g., white light, near-infrared light, fluorescent light, etc.). These methods and apparatuses may correct irregularities (e.g., holes, gaps, etc.) in the 3D digital model of the subject's teeth and may enhance treatment planning and the accuracy and effectiveness of dental appliances.
Owner:ALIGN TECHNOLOGY INC

Method and device for determining UV coverage on irradiation target in real time

A method for determining UV coverage on an irradiation target in real time comprises the steps of irradiating an irradiation target (10) with light including UV light (16) immediately after applying a sunscreen (12); detecting an amount of fluorescent light (20) emitted from the irradiation target in response to the light irradiation and storing the amount of the fluorescent light as reference data; irradiating the irradiation target (10) with the light including UV light (16) after a predetermined passage of time, or after applying a predetermined stress on the sunscreen (12); detecting an amount of fluorescent light (20) emitted from the irradiation target in response to the light irradiation and storing the amount of the fluorescent light as measurement data; and determining UV coverage by dividing the amount of the fluorescent light of the reference data by the amount of the fluorescent light of the measurement data, wherein the irradiation target (10) includes at least one substance emitting fluorescent light in response to the light irradiation.
Owner:LOREAL SA

Wide-field dynamic magnetic imaging device and method

The invention provides a wide-field dynamic magnetic imaging device and method, and the device comprises a probe assembly which comprises a diamond containing an NV color center; the microwave magnetic field assembly is suitable for generating a uniform microwave field and a uniform bias magnetic field near the diamond so as to regulate and control the spin energy level and the quantum state evolution process of the diamond; the laser modulation assembly is suitable for outputting initial uniform pulse laser to excite the diamond to emit fluorescent light; the stripe light modulation assembly is suitable for modulating the initial uniform pulse laser to output stripe pulse laser, so that fluorescent light emitted by the diamond is stripe fluorescent light; or modulating the fluorescence emitted by the diamond into stripe fluorescence; the fluorescence detection assembly is suitable for carrying out space imaging on the stripe fluorescence to obtain magnetic field information of the to-be-detected sample and further obtain an initial magnetic image of the to-be-detected sample; and a data processing component suitable for performing Fourier transform and inverse Fourier transform processing on the initial magnetic image to obtain a first magnetic image.
Owner:UNIV OF SCI & TECH OF CHINA +1

Method for manufacturing a sensor element, sensor element and machine for additive manufacturing

The invention relates to a method for manufacturing a sensor element comprising a crystal (11) with at least one color center (10) and at least one optic, comprising: arranging the crystal (11) in a processing volume (7) of a machine (1) for additive manufacturing, exciting the at least one color center (10) with a light beam, in particular with a laser beam (4), which is directed into the processing volume (7) and focused in the processing volume (7), detecting fluorescence light (13) generated when the at least one color center (10) is excited with the laser beam (4), determining a position (P(x,y,z)) of the color center (10) in the processing volume (7) based on the detected fluorescence light (13), and forming the at least one optic on the crystal (11) by additive manufacturing taking into account the determined position (P(x,y,z)) of the at least one color center (10).The invention also relates to a sensor element produced by the method, and to a machine (1) for additive manufacturing designed to carry out the method.
Owner:QUANTUM BRILLIANCE GMBH

Objective lens group, fluorescent optical system, and endoscope

The invention relates to an objective lens group, a fluorescent optical system and an endoscope. The objective lens group comprises a first lens with negative focal power, a second lens with negative focal power, a third lens with positive focal power, a fourth lens with positive focal power, a fifth lens with positive focal power, a sixth lens with negative focal power, a seventh lens with positive focal power and an eighth lens with negative focal power; a ninth lens having a negative focal power; a tenth lens having a positive focal power; and an eleventh lens having a negative focal power. The object side surface of the first lens is a convex surface, the image side surface of the first lens is a concave surface, the image side surface of the third lens is a convex surface, the image side surface of the sixth lens is a concave surface, the image side surface of the ninth lens is a concave surface, and the object side surface and the image side surface of the tenth lens are convex surfaces. The objective lens group can perform clear imaging on visible light and fluorescent light at the same time.
Owner:CHONGQING XISHAN SCI & TECH

Optical detection device for fluorescence detection

The optical detection device comprises a light emitting module and a light receiving module, the light emitting module comprises a first light source unit, a light receiving lens, a first light filter, a light combining lens and a projection lens which are arranged in sequence, and the first light source unit comprises one or more light sources; the light receiving lens converts the light beam into a light beam with a light included angle smaller than a first preset value, the light combining lens is used for deflecting and converging the light penetrating through the first optical filter, and the projection lens is used for projecting the light on a detected object so that the detected object can be excited to emit fluorescent light; the light receiving module comprises a light receiving lens, a light splitting unit, a second optical filter, a condensing lens and a sensor which are arranged in sequence, the light receiving lens is used for receiving fluorescent light and converting the fluorescent light into light beams with light included angles smaller than a second preset value, and the light splitting unit is used for guiding light with different wavelengths to different directions; and the light rays in different directions sequentially pass through the second optical filter and the condensing lens in the direction and then enter the sensor. And the light receiving and emitting efficiency is improved.
Owner:SHENZHEN TIANCHENG ZHIYUAN TECHNOLOGY CO LTD

Optical imaging system and endoscope

The invention discloses an optical imaging system and an endoscope. The optical imaging system comprises a front-end objective lens group, a relay rod lens mechanism and a rear-end eyepiece group which are sequentially arranged from the object side to the image side; the relay rod lens mechanism comprises an odd number of rod lens groups, and the odd number of rod lens groups are sequentially arranged along the optical axis from the object side to the image side; the rear-end eyepiece group comprises an eighth lens, a ninth lens and an exit pupil which are sequentially arranged along the optical axis from the object side to the image side, the eighth lens is a doublet lens, and the ninth lens is a biconvex symmetric lens; wherein the defocusing amount of the white light and the fluorescent light of the optical imaging system is not greater than 0.02 mm. According to the optical imaging system and the endoscope, the problem that refocusing is needed when the optical imaging system of the endoscope is switched between the white light mode and the fluorescent light mode can be solved.
Owner:HANGZHOU HAIKANG HUIYING TECH CO LTD

High-enthalpy flow field particle concentration measurement system and method based on two-photon laser induced fluorescence

The invention provides a high-enthalpy flow field particle concentration measurement system and method based on two-photon laser-induced fluorescence. The system comprises a laser, a high-enthalpy flow field wind tunnel module, an imaging module, an image processing module, a reflector, a three-dimensional galvanometer, a three-axis displacement table and a collecting lens. The centers of the reflecting mirror, the three-dimensional galvanometer and the collecting lens are coaxial and located on the same light path plane, and the three-dimensional galvanometer and the collecting lens are both fixedly installed on the three-axis displacement table; the laser device generates a laser beam, the laser beam is irradiated to the three-dimensional galvanometer through the reflecting mirror, the direction of the laser beam is changed by deflecting the three-dimensional galvanometer and / or moving the three-axis displacement table, and then the laser beam with the changed direction is irradiated to particles to be measured in a flow field area to be measured through the collecting mirror to generate fluorescent light; the imaging module collects fluorescence generated by irradiation of the laser beams to obtain fluorescence data; and the image processing module is used for processing the fluorescence data to obtain a three-dimensional image of the to-be-detected particle. According to the scheme, three-dimensional scanning measurement of the high-enthalpy flow field without a sheet light source is realized, the measurement precision is improved, and the requirement on the energy of the laser is reduced.
Owner:CHINA AERODYNAMICS RES AND DEV CENT ULTRA-HIGH SPEED AERODYNAMICS RES INST

Spatio-temporal monitoring of photopolymerization progression and related mechanisms

In one general aspect, a method includes, during performance of an additive manufacturing process that includes photocuring of a resin, monitoring light output generated by a fluorophore in the resin that exhibits aggregation-induced emission (AIE) behavior. An indication of an extent of photocuring is output based on the monitored light output. In another general aspect, a resin for additive manufacturing includes molecules configured for photopolymerization and / or photocuring, the molecules being selected from the group consisting of monomers, oligomers, and polymers; a photoinitiator; and a fluorophore that exhibits aggregation-induced emission (AIE) behavior. The fluorophore is present in an amount of at least 0.00005 wt% relative to a total weight of the resin. In yet another general aspect, a three-dimensional encrypted structure includes a fluorophore that exhibits aggregation-induced emission (AIE) behavior. The structure has information encoded therein via the fluorophore, the information being viewable by illuminating the fluorophore with fluorescent light.
Owner:LAWRENCE LIVERMORE NAT SECURITY LLC

Primer probe combination, kit and detection method for detecting human papilloma virus

The invention discloses a primer probe combination, a kit and a detection method for detecting human papilloma virus. The primer probe combination comprises nucleotide series as shown in SEQ ID No. 1 to SEQ ID No. 45. Probes in the primer probe group are respectively marked with different fluorescent light-emitting groups. Specific primers and corresponding specific fluorescent probes are designed for E6 / E7 DNA of 14 high-risk HPVs (HPV16, HPV18, HPV31, HPV33, HPV35, HPV39, HPV45, HPV51, HPV52, HPV56, HPV58, HPV59, HPV66 and HPV68) and an internal reference HBB, so that 14 target genes are detected by one reaction tube, and moreover, a method of combining asymmetric PCR with a multicolor multiple melting curve has the advantages of high detection sensitivity, good specificity, high flux, simplicity in operation, low cost and the like.
Owner:SHENZHEN DEXIA DIAGNOSTIC TECH CO LTD

Light, sound and light sheet bimodal imaging system

The utility model discloses an optical acousto-optic sheet bimodal imaging system, and relates to the technical field of microscopic imaging. Continuous laser; the pulse laser and the continuous laser irradiate on the dichroscope to generate reflected pulse laser and transmitted continuous laser respectively, and the reflected pulse laser and the transmitted continuous laser are combined to form a laser beam; the galvanometer reflects the laser beam to form scanning laser; the scanning objective lens transmits the scanning laser to form a scanning light beam, and the sample generates ultrasonic waves and fluorescent light under excitation of the reflected pulse laser and the transmitted continuous laser; the ultrasonic detector is used for collecting ultrasonic waves and forming corresponding ultrasonic signals; and the camera is used for collecting fluorescence to form a corresponding fluorescence signal. In the application, the pulse laser for exciting the ultrasonic wave and the continuous laser for exciting the fluorescence are highly overlapped on the light path, so that the problem of huge system size caused by independent design of the light path is avoided.
Owner:TONGCHUAN ZHIGUANG PHOTOELECTRIC TECH CO LTD

Illuminating system and projection equipment

The invention provides an illumination system and projection equipment. The lighting system comprises a light source module, a wavelength conversion device, a first light guide assembly, a second light guide assembly and a micro-lens array module. The light source module is used for providing a plurality of green and blue laser beams. The wavelength conversion device is used for generating fluorescent light beams. The first light guiding assembly and the second light guiding assembly are used for guiding a fluorescent light beam and a green laser light beam respectively. The fluorescent light beams form fluorescent light spots on the first area of the first side face of the micro-lens array module. The plurality of green laser beams form a plurality of green light spots on a second area of the first side surface of the micro-lens array module. The first region is adjacent to the second region. The illumination system and the projection equipment provided by the invention avoid energy loss and have good light uniformity.
Owner:CORETRONIC CORPORATION

Quantum dot body, quantum dot composition, and wavelength conversion material and production method thereof

PCT designated stage expiredWO2025088985A1Optical filtersNanoopticsPhosphoric acidFluorescent light
This quantum dot body comprises a quantum dot that emits fluorescent light by the action of excitation light. The quantum dot body is characterized in that the quantum dot comprises a semiconductor nanoparticle core and a semiconductor nanoparticle shell that coats the semiconductor nanoparticle core, the surface of the quantum dot is coated with a metal oxide, and the surface of the metal oxide is modified with a phosphonic acid derivative. The quantum dot body is also characterized by having a polymer coating layer on the outermost surface thereof, wherein the polymer coating layer is formed by bonding a reactive substituent in the phosphonic acid derivative to a reactive substituent in a polymer. As a result, there are provided: a quantum dot body which is further improved in stability while maintaining the fluorescence emission characteristics of a quantum dot, and is also further improved in compatibility with a highly polar solvent or a photosensitive resin composition; a quantum dot composition in which the quantum dot body is dispersed in a resin material; a wavelength conversion material obtained by curing the quantum dot composition; and a method for producing the wavelength conversion material.
Owner:SHIN ETSU CHEMICAL CO LTD

Biochemical sensor with high sensitivity, high flux and high selectivity and sensing method thereof

The invention provides a high-sensitivity, high-flux and high-selectivity biochemical sensor and a sensing method thereof. The high-sensitivity, high-flux and high-selectivity biochemical sensor comprises a light-emitting device, a container, a dispersion device, a sensing device, an array type detection chip and a calculation unit connected with the array type detection chip, according to the sensor, a coordination polymer is used as a sensing device, an array type detection chip is used as a signal detection element, and fluorescent light which is emitted by the coordination polymer and has relatively weak light intensity is used as a perturbation signal; and sensing by solving the matrix equation for multiple times and detecting whether the peak value of the restored spectral line of the standard signal with relatively strong light intensity under the influence of the perturbation signal is changed or not. The technical problems that an existing biochemical sensor is large in size, complex in structure, high in cost, low in flux, low in sensitivity, narrow in detection wave band, single in detection object, incapable of achieving real-time detection and the like are solved.
Owner:NANJING UNIV OF TRADITIONAL CHINESE MEDICINE

Multi-applicability real-time ratio light imaging device

The invention provides a multi-applicability real-time ratio light imaging device. The multi-applicability real-time ratio light imaging device comprises a host, a time schedule controller, a light source, an image acquisition unit, a prism imaging light path, a light filter rotating wheel and an all-in-one illumination light path, the time sequence controller receives a time sequence control command sent by the host and sends high-frequency time sequence signals to the image acquisition unit and the light source respectively so as to control on-off of exciting light and acquisition of fluorescent light; the light sources are used for providing exciting light for exciting the fluorescent medicine to generate fluorescent light, the all-in-one illumination light path is used for connecting the multiple light sources into the exciting illumination light path at the same time, and the light filter rotating wheel switches corresponding light filters according to different light sources and is used for stopping interference of the exciting light on fluorescent imaging of the image acquisition unit; the prism imaging light path is used for collecting fluorescence and reflecting and transmitting the fluorescence to the corresponding image collection units according to different spectrums. By means of high integration, multi-functionalization and efficient fluorescence imaging capacity, filtering switching and experiment item switching can be carried out more quickly.
Owner:BEIJING DIGITAL PRECISION MEDICAL TECH CO LTD

Apparatus and method for fluorescence detection in electronic devices with high brightness coaxial diode laser illumination

The system includes a laser light source configured to emit laser light; an optical fiber coupled to the laser light source and configured to guide the laser light along an illumination path; and an illumination optical assembly disposed in the illumination path and configured to direct the laser light on a workpiece. The workpiece emits fluorescent light along an emission path based on illumination from the laser light. The system further includes a collection optical assembly disposed in the emission path and configured to separate the fluorescent light from reflected laser light; and a detector disposed in the emission path and configured to generate one or more fluorescence images based on the fluorescent light.
Owner:ORBOTECH LTD

Optical detection system of flow type fluorescence instrument and flow type instrument

The utility model relates to the field of biological detection, in particular to an optical detection system of a flow type fluorescence instrument and the flow type instrument, which comprises an optical substrate, the optical substrate is respectively provided with a laser light source, a laser light path adjusting device, a laser shaping and focusing device, a forward scattered light receiving device, a fluorescence receiving device and a flow chamber, the laser light path adjusting device is arranged at a light outlet of a laser light source, a laser shaping and focusing device is arranged on one side of the laser light path adjusting device, and a forward scattered light receiving device, a fluorescent light receiving device and a flowing chamber are arranged beside the laser shaping and focusing device. Laser beam shaping is not carried out in the laser, and the multiple laser beams are shaped and focused at the same position in front of incidence of the flow chamber. And the use number of the shaping prisms and the debugging flexibility are reduced. Meanwhile, the receiving channels of the fluorescence receiving device are mutually independent and adjustable, and different optical filters can be replaced according to different dyes for more detection and analysis.
Owner:CHENGDU ILLUMAXBIO TECH CO LTD

Optical grain mould detection equipment

The utility model relates to optical grain mould detection equipment. The optical grain mould detection equipment structurally comprises a material barrel, a grinding mechanism, a buffer discharging device and a fluorescence detection unit, the material barrel is provided with a feeding port and a discharging port, so that feeding and discharging of materials are facilitated; the grinding mechanism comprises a fixed grinding sleeve and a movable grinding roller, and the fixed grinding sleeve and the movable grinding roller form a precise grinding gap, so that uniform refining of materials in the grinding process is ensured; the buffer discharging device comprises a discharging cavity, a movable discharging disc and a pressing disc, and the material flow speed is effectively adjusted; the fluorescence detection unit is used for efficiently detecting mould in the material through a fluorescent lamp column and a spectrum acquisition plate; the rotating motor drives the movable grinding roller to rotate, so that automatic operation is realized; the equipment is exquisite in design and comprehensive in function, and a convenient and efficient solution is provided for mould detection.
Owner:镇江市粮食和物资储备质量监测中心(镇江市军粮供应管理中心)