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392 results about "Fluorescent light" patented technology

Simply put, fluorescent lighting is a kind of lighting technology which depends on a chemical reaction inside of a glass tube to create light. This chemical reaction involves gases and mercury vapor interacting, which produces an invisible UV light.

Light-emitting super-structure surface capable of realizing incoherent fluorescent holography and multi-dimensional super-structure display and preparation method of light-emitting super-structure surface

The invention discloses a light-emitting super-structure surface capable of realizing incoherent fluorescence holography and multi-dimensional super-structure display and a preparation method thereof. The light-emitting super-structure surface is mainly composed of an optical waveguide structure layer, a micro-nano structure layer and a fluorescence emission layer. The optical waveguide structure layer comprises a substrate and a waveguide layer and is responsible for guiding fluorescence propagation; the micro-nano structure layer is located above the waveguide layer, is composed of nano bricks and can regulate and control light; the fluorescence emission layer is arranged above the micro-nano structure layer, contains quantum dots and is excited by the pump light to emit fluorescence. The metasurface can regulate and control the emergent angle, wavefront and emergent intensity of fluorescent light and pump light, the time-space coherence of the fluorescent light is enhanced through the waveguide layer, and phase modulation is carried out by using a method based on a circuitous phase. Based on the super-structure surface, through the steps of fluorescence excitation, coherence enhancement, phase modulation, diffraction calculation, hologram generation, multi-dimensional display and the like, incoherent fluorescence hologram and multi-dimensional super-structure display can be achieved, and the functions of fluorescence nanometer printing and multi-channel holographic display are covered.
Owner:WUHAN UNIV

Bright field and fluorescence integrated scanning equipment

The utility model relates to bright field and fluorescent light integrated scanning equipment, which comprises an equipment rack, a bright field light path assembly used for forming a bright field light path and a fluorescent light path assembly used for forming a fluorescent light path, the bright field light path assembly comprises a bright field camera, a light path pipe diameter, objective lens equipment, a slide holder for bearing a sample and a bright field light source module; the fluorescent light path assembly comprises a fluorescent camera, a light path pipe diameter shared by the fluorescent camera and the bright field light path, a fluorescent turntable, objective lens equipment, a slide holder and a fluorescent light source module; the bright field and fluorescence integrated scanning equipment is provided with a camera switching device; the objective lens equipment comprises a plurality of objective lenses with different multiplying powers, and the bright field light source module is provided with a diaphragm switching device for switching diaphragms based on the multiplying powers of the objective lenses; the slide holder is provided with a scanning motion module for moving the slide holder. According to the utility model, integration of bright field fluorescence is realized, the cost is reduced, and the system has the characteristics of better imaging effect and higher efficiency.
Owner:NINGBO SUNNY INSTR

Irradiation module and device and method for irradiation with medical and cosmetic radiation

The invention relates to an irradiation module for use in a device (1) for irradiation with medical and cosmetic radiation, comprising a plurality of LEDs arranged on a carrier. The invention also relates to a device for irradiating a user (10) with medical and cosmetic radiation, comprising a plurality of irradiation modules (40) for irradiation with medical and cosmetic radiation, which modules are accommodated in a housing part (20; 30). The invention further relates to a method for irradiating a user (10) with medical and cosmetic radiation, comprising a plurality of irradiation modules (40) for irradiation with medical and cosmetic radiation, which modules are selected from the group comprising fluorescent tubes, LEDs, organic LEDs, and high-pressure lamps. In order to provide an irradiation module and a device and a method with which improved irradiation results can be achieved according to the invention, a first group of first LEDs, which emits radiation within the UVA spectrum, and a second group of second LEDs, which emits radiation within the UVB spectrum, are arranged on the carrier.
Owner:JK HLDG

Microscope fluorescence optical filter switching device

The utility model discloses a microscope fluorescent light filter switching device, which relates to the technical field of biological experiment instruments and comprises a lens switching mechanism, a lens butt joint mechanism and a fluorescent light source assembly. A plurality of fluorescent light filters on the microscope body are arranged on the lens switching mechanism, and the lens switching mechanism is arranged between an eyepiece and an objective lens on the microscope body through the lens butt joint mechanism and the fluorescent light source assembly. The fluorescent light filter switching device is simple in structure and convenient to use, can rapidly switch a plurality of fluorescent light filters, effectively improves the efficiency and precision of fluorescent microscopic observation, reduces the risk of damage of the light filters, and is suitable for various fluorescent microscopic experiments.
Owner:THE FIRST AFFILIATED HOSPITAL OF HAINAN MEDICAL UNIV

Magnetic field sensor and method for calibrating the temperature of a magnetic field sensor

The invention relates to a magnetic field sensor (10), comprising: an excitation light source (6) for emitting excitation light (4), a measurement region (7) which has colour centres (3) in a crystal (1), preferably NV centres in a diamond, which emit fluorescent light (5) when excited with the excitation light (4), a detector (8) for detecting the fluorescent light (5) from the measurement region (7), a microwave emitter (11) for applying a microwave field (9) to the measurement region (7), a signal generator (14) which is designed to generate a microwave signal (15) for the microwave emitter (11) and has two frequency components (fsb-(t), fsb+,π(t)) phase-shifted in relation to one another by π, in order to simultaneously excite magnetic field resonances at two different resonant frequencies (f-, f+) in the crystal (1) in order to determine a magnetic field (B), and an evaluation device (12) which has a demodulator (13) for forming a demodulated magnetic resonance signal from the detected fluorescent light (5) of the measurement region (7), wherein the evaluation device (12) is designed to determine a detuning (∆B) of the resonant frequencies (f-, f+) due to a change in the magnetic field (B), and to generate a frequency shift (∆f) of the microwave signal (15) according to the magnetic-field-related detuning (∆B) of the resonant frequencies (f-, f+). The magnetic field sensor (10) is designed to determine, in a temperature calibration step, a temperature-related detuning (∆T) of the resonant frequencies (f-, f+) and to take same into account in the frequency shift (∆f) of the microwave signal (15) in order to determine the magnetic field (B). The invention further relates to an associated method for calibrating the temperature of a magnetic field sensor (10).
Owner:Q ANT GMBH

Three-dimensional modeling of interproximal spaces

PendingUS20250265798A1Image enhancementImpression capsInterproximal spaceDental instruments
Methods and apparatuses that may improve the accuracy of three-dimensional models from interproximal regions of intraoral scan data using non-structured light illumination images (e.g., white light, near-infrared light, fluorescent light, etc.). These methods and apparatuses may correct irregularities (e.g., holes, gaps, etc.) in the 3D digital model of the subject's teeth and may enhance treatment planning and the accuracy and effectiveness of dental appliances.
Owner:ALIGN TECHNOLOGY INC

Method and device for determining UV coverage on irradiation target in real time

A method for determining UV coverage on an irradiation target in real time comprises the steps of irradiating an irradiation target (10) with light including UV light (16) immediately after applying a sunscreen (12); detecting an amount of fluorescent light (20) emitted from the irradiation target in response to the light irradiation and storing the amount of the fluorescent light as reference data; irradiating the irradiation target (10) with the light including UV light (16) after a predetermined passage of time, or after applying a predetermined stress on the sunscreen (12); detecting an amount of fluorescent light (20) emitted from the irradiation target in response to the light irradiation and storing the amount of the fluorescent light as measurement data; and determining UV coverage by dividing the amount of the fluorescent light of the reference data by the amount of the fluorescent light of the measurement data, wherein the irradiation target (10) includes at least one substance emitting fluorescent light in response to the light irradiation.
Owner:LOREAL SA

Objective lens group, fluorescent optical system, and endoscope

The invention relates to an objective lens group, a fluorescent optical system and an endoscope. The objective lens group comprises a first lens with negative focal power, a second lens with negative focal power, a third lens with positive focal power, a fourth lens with positive focal power, a fifth lens with positive focal power, a sixth lens with negative focal power, a seventh lens with positive focal power and an eighth lens with negative focal power; a ninth lens having a negative focal power; a tenth lens having a positive focal power; and an eleventh lens having a negative focal power. The object side surface of the first lens is a convex surface, the image side surface of the first lens is a concave surface, the image side surface of the third lens is a convex surface, the image side surface of the sixth lens is a concave surface, the image side surface of the ninth lens is a concave surface, and the object side surface and the image side surface of the tenth lens are convex surfaces. The objective lens group can perform clear imaging on visible light and fluorescent light at the same time.
Owner:CHONGQING XISHAN SCI & TECH

Optical detection device for fluorescence detection

The optical detection device comprises a light emitting module and a light receiving module, the light emitting module comprises a first light source unit, a light receiving lens, a first light filter, a light combining lens and a projection lens which are arranged in sequence, and the first light source unit comprises one or more light sources; the light receiving lens converts the light beam into a light beam with a light included angle smaller than a first preset value, the light combining lens is used for deflecting and converging the light penetrating through the first optical filter, and the projection lens is used for projecting the light on a detected object so that the detected object can be excited to emit fluorescent light; the light receiving module comprises a light receiving lens, a light splitting unit, a second optical filter, a condensing lens and a sensor which are arranged in sequence, the light receiving lens is used for receiving fluorescent light and converting the fluorescent light into light beams with light included angles smaller than a second preset value, and the light splitting unit is used for guiding light with different wavelengths to different directions; and the light rays in different directions sequentially pass through the second optical filter and the condensing lens in the direction and then enter the sensor. And the light receiving and emitting efficiency is improved.
Owner:SHENZHEN TIANCHENG ZHIYUAN TECHNOLOGY CO LTD

Spatio-temporal monitoring of photopolymerization progression and related mechanisms

In one general aspect, a method includes, during performance of an additive manufacturing process that includes photocuring of a resin, monitoring light output generated by a fluorophore in the resin that exhibits aggregation-induced emission (AIE) behavior. An indication of an extent of photocuring is output based on the monitored light output. In another general aspect, a resin for additive manufacturing includes molecules configured for photopolymerization and / or photocuring, the molecules being selected from the group consisting of monomers, oligomers, and polymers; a photoinitiator; and a fluorophore that exhibits aggregation-induced emission (AIE) behavior. The fluorophore is present in an amount of at least 0.00005 wt% relative to a total weight of the resin. In yet another general aspect, a three-dimensional encrypted structure includes a fluorophore that exhibits aggregation-induced emission (AIE) behavior. The structure has information encoded therein via the fluorophore, the information being viewable by illuminating the fluorophore with fluorescent light.
Owner:LAWRENCE LIVERMORE NAT SECURITY LLC

Illuminating system and projection equipment

The invention provides an illumination system and projection equipment. The lighting system comprises a light source module, a wavelength conversion device, a first light guide assembly, a second light guide assembly and a micro-lens array module. The light source module is used for providing a plurality of green and blue laser beams. The wavelength conversion device is used for generating fluorescent light beams. The first light guiding assembly and the second light guiding assembly are used for guiding a fluorescent light beam and a green laser light beam respectively. The fluorescent light beams form fluorescent light spots on the first area of the first side face of the micro-lens array module. The plurality of green laser beams form a plurality of green light spots on a second area of the first side surface of the micro-lens array module. The first region is adjacent to the second region. The illumination system and the projection equipment provided by the invention avoid energy loss and have good light uniformity.
Owner:CORETRONIC CORPORATION

Apparatus and method for fluorescence detection in electronic devices with high brightness coaxial diode laser illumination

The system includes a laser light source configured to emit laser light; an optical fiber coupled to the laser light source and configured to guide the laser light along an illumination path; and an illumination optical assembly disposed in the illumination path and configured to direct the laser light on a workpiece. The workpiece emits fluorescent light along an emission path based on illumination from the laser light. The system further includes a collection optical assembly disposed in the emission path and configured to separate the fluorescent light from reflected laser light; and a detector disposed in the emission path and configured to generate one or more fluorescence images based on the fluorescent light.
Owner:ORBOTECH LTD

Optical grain mould detection equipment

The utility model relates to optical grain mould detection equipment. The optical grain mould detection equipment structurally comprises a material barrel, a grinding mechanism, a buffer discharging device and a fluorescence detection unit, the material barrel is provided with a feeding port and a discharging port, so that feeding and discharging of materials are facilitated; the grinding mechanism comprises a fixed grinding sleeve and a movable grinding roller, and the fixed grinding sleeve and the movable grinding roller form a precise grinding gap, so that uniform refining of materials in the grinding process is ensured; the buffer discharging device comprises a discharging cavity, a movable discharging disc and a pressing disc, and the material flow speed is effectively adjusted; the fluorescence detection unit is used for efficiently detecting mould in the material through a fluorescent lamp column and a spectrum acquisition plate; the rotating motor drives the movable grinding roller to rotate, so that automatic operation is realized; the equipment is exquisite in design and comprehensive in function, and a convenient and efficient solution is provided for mould detection.
Owner:镇江市粮食和物资储备质量监测中心(镇江市军粮供应管理中心)

Wafer detection device for stimulated radiation

According to the stimulated radiation wafer detection device provided by the invention, the excitation light beam generated by the excitation light source is collimated, dodging and shape-modulated by the first illumination lens group to form a uniform shaping light beam; a convergent light beam generated by converging the shaped light beam through the second illuminating lens group can form an emergent light beam after passing through the light beam separation element and the objective lens, the emergent light beam irradiates the surface of a wafer to excite and generate fluorescent light, the objective lens receives the fluorescent light and transmits the fluorescent light to the light beam separation element, and the fluorescent light is transmitted by the light beam separation element and transmitted to the camera; the camera captures fluorescence and carries out fluorescence imaging so as to realize wafer detection. The light source energy can be efficiently utilized by adopting the shaping light beam for illumination; meanwhile, one-time or multi-time convergence of converged light beams in an illumination light path can be avoided, heat energy is prevented from being generated in a concentrated mode, obvious heat influence caused by high-energy convergence is avoided, deformation of surrounding optical elements or structural elements due to heat influence is avoided, the illumination service life is prolonged, and the illumination effect is improved.
Owner:SKYVERSE TECH CO LTD

Light source device and projection display device

The present application relates to a light source device and a projection display device. In a light source device in which fluorescent light and a part of blue light emitted from a semiconductor laser are output, a light source device in which the device does not excessively increase in size is sought. The light source device includes: a laser light source that outputs light in a predetermined wavelength region; a first dichroic mirror and a second dichroic mirror that have a characteristic of transmitting fluorescent light while reflecting light in the predetermined wavelength region, and are disposed on an optical axis of the laser light source; a first condensing optical system; a fluorescent color wheel that has a fluorescent light region that emits fluorescent light and a reflection region; a fourth dichroic mirror that has a characteristic of reflecting fluorescent light; a third dichroic mirror that has a characteristic of transmitting fluorescent light while reflecting light in the predetermined wavelength region, and is disposed so that an optical axis of the reflected light in the predetermined wavelength region coincides with an optical axis of the fluorescent light reflected by the fourth dichroic mirror; a second condensing optical system; and a light color selection color wheel that has a color filter and a diffusion portion.
Owner:索诺克(苏州)光电有限公司

Integrated automatic imaging and identification analysis device for two insects and plankton in water

The utility model relates to an integrated automatic imaging and identification analysis device for two insects and plankton in water. The integrated automatic imaging and identification analysis device comprises a camera, a fluorescent light source, an electric objective table, a driving mechanism, an objective lens, an electric objective table and a backlight source. The objective lens comprises a two-insect objective lens and a plankton objective lens (switchable), or only the two-insect objective lens is used for switching detection. The two-worm objective lens is 40 times, the floating objective lens is 20 times, or the camera is integrated with the 20 times objective lens. The driving mechanism is diversified and comprises a motor, a guide rail, a synchronous belt, a proximity sensor and a synchronous belt pressing block. The device solves the problems that traditional detection is low in efficiency, poor in accuracy and insufficient in equipment adaptability, automatic imaging and recognition analysis of the two insects and the plankton are achieved, the water resource pollution source monitoring efficiency and quality are improved, and technical support is provided for water ecological environment protection and treatment.
Owner:浙江泰林生命科学有限公司

Quantensensor

The invention relates to a quantum sensor (1), in particular for magnetic field measurement, comprising: a sensor element (4) in the form of a crystal doped with color centers (5), in particular a diamond crystal doped with NV centers, wherein the color centers (5) are designed to generate fluorescent light (7) upon excitation with excitation light (6), a carrier substrate (2) having a surface (2a) to which the sensor element (4) is attached, and a detector (8), in particular a photodiode, for detecting the fluorescent light (7). In the quantum sensor (1), the carrier substrate (2) has a waveguide (3) for supplying the excitation light (6) to the sensor element (4).
Owner:INST FOR MICROELECTRONICS STUTTGART - FOUNDATION OF CIVIL LAW +1

Spatio-temporal monitoring of photopolymerization progression and related mechanisms

In one general embodiment, a method includes, during performance of an additive manufacturing process that includes photocuring of a resin, monitoring light output generated by a fluorophore in the resin that exhibits aggregation-induced emission (AIE) behavior. An indication of an extent of photocuring is output based on the monitored light output. In another general embodiment, a resin for additive manufacturing includes molecules configured for photopolymerization and / or photocuring, the molecules being selected from the group consisting of monomers, oligomers, and polymers; a photoinitiator; and a fluorophore that exhibits aggregation-induced emission (AIE) behavior. The fluorophore is present in an amount of at least 0.00005 wt % relative to a total weight of the resin. In yet another general embodiment, a three-dimensional encrypted structure includes a fluorophore that exhibits aggregation-induced emission (AIE) behavior. The structure has information encoded therein via the fluorophore, the information being viewable by illuminating the fluorophore with fluorescent light.
Owner:LAWRENCE LIVERMORE NAT SECURITY LLC

A polyimide supported triaminophthalocyanine probe, a preparation method thereof and application thereof in detection of nitroaromatic explosives

The application belongs to the field of explosive detection, and discloses a polyimide loaded triaminophthalocyanine probe, a preparation method thereof and application thereof in detecting nitroaromatic explosives. The probe has the following general structure formula. The probe is prepared by cross-linking copolymerization of 5,10,15-tri(4-aminophenyl)-20-phenyl porphyrin, aromatic tetracid dianhydride and aromatic organic diamine. The polyimide high-molecular cross-linked branch loaded triaminophthalocyanine compound with fluorescent light emitting performance is prepared for the first time. The probe is applied to detecting various nitroaromatic explosives by quenching fluorescence response, and the detection method is simple, and has good application prospect in the field of public security.
Owner:CHINA SCI CERTIFICATION TECH SERVICES (GUANGZHOU) CO LTD +1

Light emitting device

Provided is a light-emitting device with high reliability. The light-emitting device includes a first electrode formed on an insulating surface, a second electrode facing the first electrode, and an EL layer between the first electrode and the second electrode, one of the first electrode and the second electrode is an anode, and the other is a cathode, the EL layer includes a light-emitting layer, a first layer, and a second layer, the first layer and the second layer are between the light-emitting layer and the cathode, the first layer is between the first electrode and the second layer, the second layer is between the first layer and the second electrode, the light-emitting layer contains a first light-emitting substance and a second light-emitting substance, the first light-emitting substance is a substance capable of converting triplet excitation energy into light emission, the second light-emitting substance is a fluorescent light-emitting substance, the light emission peak wavelength of the first light-emitting substance is shorter than the light emission peak wavelength of the second light-emitting substance, and the GSP_Slope of the second layer is greater than the GSP_Slope of the first layer.
Owner:SEMICON ENERGY LAB CO LTD

Fluorescence diffusion tomography system with double-line simultaneous scanning excitation

The invention discloses a fluorescence diffusion tomography system capable of scanning and exciting two lines simultaneously, and relates to the field of optical and biomedical engineering, and the system comprises a rotary objective table which is used for placing a sample and driving the sample to rotate; the laser scanning module is used for emitting double-line exciting light to scan and excite the sample, so that a fluorescent target in the sample generates fluorescent light; and the detection module is used for detecting the double-line exciting light and the fluorescent light, performing reverse image reconstruction according to the double-line exciting light and the fluorescent light, and generating a three-dimensional image of the fluorescent target in the sample. According to the method, the overall reconstruction quality of FDT imaging can be further improved while the high imaging rate is kept.
Owner:HUAZHONG UNIV OF SCI & TECH

Method for the selective concentration and / or separation of metal compounds

The present invention relates to a method for the selective concentration and / or separation of metal compounds from particulate material using magnetic nanoparticles modified with at least one organic acid in an aqueous solution, preferably with a pH value in the range of pH 3.5 to pH 11, and the use for the recycling of rare-earth compounds, preferably for the recycling of rare-earth oxides from fluorescent lamps.
Owner:HELMHOLTZ ZENTRUM DRESDEN ROSSENDORF

Light emitting device and display apparatus

The invention relates to a light emitting device and a display apparatus. The light-emitting device comprises a light-emitting layer, the light-emitting layer comprises a first light-emitting layer, a phosphorescence sensitization light-emitting layer and a second light-emitting layer which are sequentially stacked, and the phosphorescence sensitization light-emitting layer comprises a host material, a phosphorescence sensitizer and a fluorescent light-emitting material. According to the light-emitting device applying the technical scheme, the phosphorescence sensitization light-emitting layer located between the first light-emitting layer and the second light-emitting layer comprises the main body material, the phosphorescence sensitizer and the fluorescence light-emitting material, light-emitting layer exciton composite area distribution can be fully utilized, namely, the middle is high, the two sides are low, and the light-emitting efficiency of the light-emitting device is guaranteed. The efficiency of the device is improved by fully utilizing excitons at a high-exciton concentration part through a phosphorescence-sensitized fluorescent light emitting technology, and wide application is facilitated.
Owner:BEIJING VISIONOX TECHNOLOGY CO LTD

Visible fluorescent viewing system

Disclosed herein are viewing systems configured for viewing an image of a biological object illuminated with light and a viewing device (e.g., loupes, glasses, etc.) and methods for operation thereof. The viewing device comprises a plurality of viewing modes: a white light mode, a fluorescent light mode, and an overlay mode, and a shutter that opens and closes in accordance with the viewing mode. An overlay image is an image of the biological object when the biological object is illuminated with both white light and fluorescent light, causing the overlay image to be an overlay of the white light image and the fluorescent light image. The disclosed systems and methods allow a user (e.g., a surgeon, medical staff, etc.) to preserve the ergonomics offered by eyewear while providing fluorescent viewing capabilities, particularly with visible fluorescent dyes.
Owner:STRYKER CORP

Electric insect killer

ActiveJP1809071SAnimal scienceZoology
This product is an electric insect killer. It has a fluorescent light and a high-voltage wire inside, and the fluorescent light attracts insects, which then come into contact with the high-voltage wire and are electrocuted.
Owner:李四芳

Phosphor wheel unit and projection-type image display device

To provide a phosphor wheel unit and a projection type image display device having improved cooling efficiency.SOLUTION: The phosphor wheel unit includes a phosphor wheel configured to emit fluorescent light from incident light, a motor configured to rotationally drive the phosphor wheel, a first heat exchanger having an airflow inlet surface on which a plurality of fins are arranged and into which a part or all of an airflow generated by rotation of the phosphor wheel flows, and a restriction member configured to restrict a direction of the airflow generated by the rotation of the phosphor wheel. On a plane perpendicular to the direction in which the base 107f of the phosphor wheel extends, the angle between the direction of the airflow restricted by the restriction member and the direction perpendicular to the axis of rotation of the phosphor wheel is greater than or equal to 0 degrees but smaller than or equal to 45 degrees. The airflow inlet surface is disposed on the extension of the direction of the airflow restricted by the restriction member, and the gas cooled by the first heat exchanger returns to the phosphor wheel.SELECTED DRAWING: Figure 7
Owner:PANASONIC PROJECTOR & DISPLAY CORPORATION

Mouthwash to deliver dyes for dental imaging

A mouthwash for fluorescence endoscopic dental imaging includes at least one fluorescent dye and a liquid base. A method for fluorescent endoscopic dental imaging includes orally administering a mouthwash to a subject; waiting a predetermined period of time; removing excess mouthwash from the subject; illuminating the subject with visible or near-infrared light; and capturing fluorescent light from the subject to create an image.
Owner:BOARD OF SUPERVISORS OF LOUISIANA STATE UNIV & AGRI & MECHANICAL COLLEGE

Bifocal reflection-type atomic fluorescence detection system for atomic beam interferometer

The invention discloses a bifocal reflection-type atomic fluorescence detection system for an atomic beam interferometer. The bifocal reflection-type atomic fluorescence detection system comprises a vacuum cavity, a reflector and a detector, the vacuum cavity is a sealed cavity; an atomic beam generated by an atomic furnace mounted in the vacuum cavity is propagated in the y-axis direction in the vacuum cavity; a window is formed in the cavity wall of the vacuum cavity in the x-axis direction, and detection light enters the vacuum cavity from the window and propagates in the x-axis direction; windows are formed in the opposite positions of the two sides of the vacuum cavity wall in the + / -z axis direction, and a reflecting mirror and a detector are correspondingly installed outside the windows respectively; the propagation directions of the atomic beam and the detection light are perpendicular to each other, and in an intersection area of the atomic beam and the detection light, atoms absorb the detection light to jump to a high energy level and then spontaneously radiate fluorescence, namely an atomic fluorescence light source; the atomic fluorescent light source emits isotropic fluorescent light to the periphery, a part of the light irradiates the reflector and is focused on the receiving end face of the detector after being reflected, and the detector detects a fluorescent signal, converts the fluorescent signal into an electric signal and reads the electric signal.
Owner:BEIJING INST OF AEROSPACE CONTROL DEVICES

Method for measuring one or more indexes of non-viral nucleic acid vector

A method for measuring drug content indexes of a non-viral nucleic acid vector composition, comprising performing labeling by enabling a permeable nucleic acid dye to be in contact with a non-viral nucleic acid vector (for example, an mRNA-LNP). The drug content indexes are calculated by measuring, at a single-particle level, fluorescent light generated by free nucleic acids of a nucleic acid vector, and fluorescent light generated by externally adsorbed nucleic acids and internally entrapped nucleic acids of the non-viral nucleic acid vector. The drug content indexes include a drug loading capacity, entrapment efficiency and the like. The method optionally further comprises: treating a sample with a nuclease before or after performing labeling by using the permeable nucleic acid dye, and when performing treatment with the nuclease, measuring the fluorescence condition of the non-viral nucleic acid vector composition; or enabling the permeable nucleic acid dye to be in contact with the sample, and then measuring the fluorescence condition of the non-viral nucleic acid vector composition.
Owner:NANOFCM INC