6090results about "Material analysis by observing effect on chemical indicator" patented technology

The present invention relates to a humidity sensor, and more particularly, to a resistance film-type real-time chromogenic humidity sensor produced with a polyelectrolyte thin film. The humidity sensor according to the present invention is a chromogenic hygrometer in which a polyelectrolyte nano thin film that absorbs moisture is formed on a reflective layer, and the nano thin film varies terms of color and electrical resistance as moisture is absorbed and the thickness varies. The hygrometer according to the present invention is a dual-function hygrometer, the color and resistance of which vary. Provided is the chromogenic hygrometer in which the sensor made using a PSS-b-PMB thin film varies in color between purple, blue, green, yellow, orange, and red according to humidity at a very high response speed of within one minute.

To provide a sample analyzer capable of achieving shortening of a measurement time and improvement of efficiency, in an inspection using a reaction to a plurality of kinds of reaction substances whose measurement ranges are largely different.SOLUTION: A sample analyzer 1 includes: a measurement unit 23 as an imaging device for capturing an image including light reception information based on each reaction between a first reaction substance group comprising a plurality of kinds of reaction substances reacting to a component included in a sample and a second reaction substance which reacts to the component included in the sample and is a different type from a reaction substance included in the first reaction substance group; and a control unit 50 as a control device for analyzing, in the light reception information in the image, the light reception information on the basis of a first determination value corresponding to a first substance group and the light reception information on the basis of a second determination value corresponding to a second substance.SELECTED DRAWING: Figure 10

The invention discloses a self-powered biosensor for double-signal detection of sugarcane pokkah boeng disease, the self-powered biosensor comprises an anode, a cathode and an electrolyte, the anode is a CuCo-MOF / AuNPs / GOD biological anode, the cathode is a CuCo-MOF / AuNPs / DNA chain biosensor, and the electrolyte comprises glucose, MB and a PBS buffer solution. According to the self-powered biosensor, analysis is carried out through two non-interfering modes of electrochemical detection and colorimetric detection, and whether a detection result is a false positive signal or not can be effectively verified. An external power supply is not needed, and real-time outdoor detection can be realized. The material source is wide, the assembly process is simple, and accurate and rapid detection can be realized. The method has the advantages of high sensitivity, good selectivity and real-time detection, and can be used for accurately detecting the sugarcane pokkah boeng rot.

The invention discloses a method for detecting glufosinate-ammonium residues in coffee in dual modes of colorimetry and chemiluminescence, and belongs to the technical field of chemical analysis and detection.The method comprises the steps that Schiff base formed by 4-aminoantipyrine and glutaraldehyde serves as a complexing agent of Cu < 2 + >, and then a copper-doped carbon dot Cu-CDs nano-enzyme is prepared through microwave digestion; according to the present invention, the Cu-CDs nano-enzyme has excellent peroxidase-like activity, can oxidize the colorless 2, 2 '-biazo-bis-3-ethylbenzothiazoline-6-sulfonic acid into the blue-green oxidized ABTS, and can improve the chemiluminescence intensity of the reaction of N-(4-aminobutyl)-N-ethylisoluminol and H2O2 by nearly 100 times when the Cu-CDs nano-enzyme is used as the chemiluminescence catalyst; based on the inhibition effect of glufosinate-ammonium on the activity of Cu-CDs POD, a sensitive and rapid colorimetric and chemiluminescence two-channel GM detection technology is developed, and the method has potential application value in the aspect of coffee safety monitoring.

The invention relates to a preparation method of Pt monatomic nano-enzyme and application of Pt monatomic nano-enzyme in cardiac troponin I. The preparation method comprises the following steps: 1) ultrasonically dispersing cobalt salt, selenium powder, chloroplatinic acid, urea and sodium chloride in an alcohol solvent, heating and stirring until the solvent is completely volatilized to obtain a solid mixture, and grinding the solid mixture into powder; and 2) placing the powder in a heating device, carrying out Joule heat treatment in an air atmosphere, washing a reactant, and carrying out vacuum drying to obtain the Pt monatomic nano-enzyme. Se doping is introduced in the one-step chemical reaction process to construct oxygen vacancies, rapid heating and structural shaping are achieved in combination with Joule heat treatment, the Se-doped Co3O4-loaded Pt monatomic catalyst is obtained, the oxygen vacancies and Se doping sites are synergistically used as anchoring sites, Pt monatomic atoms are effectively fixed, and the loading capacity and dispersity of the Pt monatomic atoms are improved. The obtained material shows excellent POD-like enzyme activity, can be used for constructing a high-sensitivity colorimetric immunoassay system, and realizes rapid and accurate detection of cTnI.

The invention provides a portable water quality detection system based on multi-sensor fusion, self-calibration and image recognition, and relates to the technical field of water quality detection.Water quality parameters are collected through multi-sensor fusion, data are processed in combination with the deep learning self-calibration and image recognition technology, and a comprehensive water quality analysis result is generated; the system integrated communication module uploads data to a cloud end in real time, low-power-consumption power management is achieved, portable deployment of field and emergency scenes is supported, the detection accuracy, intelligence and real-time monitoring capacity are remarkably improved, and efficient water quality safety supervision is achieved.

The invention belongs to the technical field of creatine kinase detection kits, and particularly relates to a creatine kinase detection reagent, a creatine kinase detection kit and application, the creatine kinase detection reagent comprises a buffer solution, creatine phosphate, glycerol, glycerol kinase, glycerophosphate oxidase, peroxidase and a color developing agent, and further comprises a CK activation reducing agent and perfluoro and polyfluoroalkyl substances, the CK activation reducing agent is a sulfur-containing reducing agent. According to the method, the detection accuracy can be improved.

The invention relates to a method for detecting pyridine in air, a test paper sheet is placed in an air environment to be detected, the color change of the test paper sheet is observed, the pyridine concentration is qualitatively judged or quantitatively judged according to the color change of the test paper sheet, and the test paper sheet is made of a filter paper sheet and a zinc-based organic-inorganic hybrid halide material. According to the method, qualitative or semi-quantitative judgment of the pyridine concentration in the air can be performed by adopting a test paper sheet and a color card or a linear correlation model standard curve graph, so that whether the pyridine content in the air exceeds the standard or not or the exceeding amplitude can be monitored, and the method has the advantages of convenience in operation and more convenience in detection.

The invention relates to the technical field of total phosphorus detection, in particular to a method for determining total phosphorus in water, which comprises the following steps: 1) digestion treatment: adding an oxidant into a water sample to be detected, and then performing microwave digestion treatment to obtain digested water; a molybdate reagent is added into the digested water, then an improved ascorbic acid solution is added, a chromogenic reaction is completed at the set temperature, and the improved ascorbic acid solution is obtained by mixing an ascorbic acid solution and sodium ethylene diamine tetracetate; measuring the concentration: measuring the absorbance value of the obtained color development product by using a spectrophotometer and a long-optical-path cuvette; and drawing a standard curve: using a phosphorus standard solution as a quality control sample, adding a plurality of calibration points in a low-concentration interval of 0.0-0.1 mg / L, carrying out colorimetric determination, and establishing quadratic equation fitting according to absorbance and concentration so as to determine the total phosphorus content of the water sample to be detected, and the method has the advantages of high sensitivity and good accuracy in total phosphorus testing.

A method for analyzing a sample includes introducing the sample into a vessel including a cation-exchange resin, where the cation-exchange resin has a high affinity to one or more interferent species in the sample, directing the sample through the cation-exchange resin to thereby capture one or more interference species in the cation-exchange resin to purify the sample, and releasing the purified sample from the vessel. Additionally, a method for analyzing a sample includes receiving an image depicting a diagnostic test region and a color reference chart, converting a test region image portion of the image to an analytical color space, determining first and second coordinate values characterizing the test region image portion in the analytical color space, and providing a quantitative measurement of an analyte of interest in the sample based on the first and / or second coordinate values and a predictive formula based on the color reference chart.

The invention relates to the technical field of spectral analysis, and discloses a visible spectrum noise reduction and heavy metal ion detection method, which comprises the following steps: reacting a water sample to be detected with a color developing agent to generate a color developing system, obtaining a gray spectrum signal through optical imaging equipment, carrying out variational mode decomposition, optimizing the signal by adopting singular value decomposition, and calculating the noise of the heavy metal ions. And determining an optimal reconstruction order by using a particle swarm optimization algorithm and reconstructing a signal, finally extracting a feature value from the denoised spectral signal, and predicting the type and concentration of metal ions through a neural network model. Spectral global / local features are modeled through cooperation of multi-head self-attention and learnable position coding, signal frequency-time domain cross-modal fusion is realized in combination with variational mode decomposition and cross attention, training parameters are dynamically optimized by innovatively adopting a reinforcement learning strategy, classification and regression tasks are self-adaptively balanced based on a gradient diversity reward mechanism, and frequency-time domain cross-modal fusion is realized. And finally, dual precision improvement of ion type identification and concentration prediction and model robustness enhancement are realized in a complex noise scene.

The invention discloses a nucleic acid aptamer of enrofloxacin and ciprofloxacin, an enzyme sensor and application thereof, and belongs to the technical field of nucleic acid aptamers. The nucleotide sequence of the nucleic acid aptamer for the enrofloxacin and the ciprofloxacin is shown as SEQ ID NO.3. The invention also discloses application of the nucleic acid aptamer for the enrofloxacin and the ciprofloxacin in detection of the enrofloxacin and the ciprofloxacin. The enzyme sensor comprises the following components: nucleic acid aptamers of enrofloxacin and ciprofloxacin, an auxiliary chain H1, an auxiliary chain H2, an auxiliary chain H3, copper sulfate and a TMB (Tetramethylbenzidine) developing solution. The enzyme sensor is applied to detection of enrofloxacin and ciprofloxacin. The nucleic acid aptamer of the enrofloxacin and the ciprofloxacin is obtained through optimization and transformation and has higher affinity to a target, the Kd value of the nucleic acid aptamer to the enrofloxacin is 15 nM, and the Kd value of the nucleic acid aptamer to the CIP is 123 nM. The enzyme sensor disclosed by the invention can realize specific recognition of ENR and CIP, is high in sensitivity and has a wide application prospect.

The present invention belongs to the technical fields of nanomaterials, analytical detection, and food safety, and specifically relates to a single-atom POD-mimicking enzyme nanomaterial, a preparation method thereof, and a food safety detection application. The single-atom POD-mimicking enzyme nanomaterial comprises a noble metal Os and a defective metal oxide, wherein the defective metal oxide is an oxide of metal Cu, and the Os is anchored on the defective metal oxide in the form of single atoms. The present invention also relates to the use of the single-atom POD-mimicking enzyme nanomaterial in the preparation of a detection reagent having POD activity and in the colorimetric detection of hydrogen peroxide or nitrite.

The invention discloses an application of CD4 + CD8 + double-positive T cells in improvement of poor immune reconstitution of HIV (human immunodeficiency virus) infected patients, and relates to the technical field of biological pharmacy, in particular to the application of preparation of the CD4 + CD8 + double-positive T cells in the poor immune reconstitution of the HIV infected patients. The number of peripheral blood CD4 + T cells of HIV infected patients is increased, the immune system of the patients is improved, and the probability of possible opportunity infection and other related diseases of the patients is reduced, so that the morbidity and mortality of the patients are reduced.

The invention discloses preparation of a bionic copper-based MOF nano-enzyme and application of the bionic copper-based MOF nano-enzyme in hydroquinone detection, and the bionic copper-based MOF nano-enzyme is prepared by the following method: dissolving terephthalic acid H2BDC and L-histidine His in N, N-dimethylformamide DMF to obtain a solution A; adding copper chloride CuCl2. 2H2O into the solution A obtained by C1, and stirring to form a uniform mixed solution; carrying out hydrothermal reaction on the mixed solution obtained from C2 for a certain time, centrifuging to obtain a solid precipitate, cleaning the solid precipitate, and drying to obtain the bionic Cu / His-MOF nano-enzyme; the invention also discloses an application of the sensor in hydroquinone detection. The bionic copper-based MOF nano-enzyme has the advantages of being simple and convenient to synthesize, high in substrate affinity, high in catalytic capacity and the like, and meanwhile, a rapid, sensitive and reliable HQ detection method is provided.

The invention discloses a preparation method of Au (at) Au (at) Ag / Pt / M NPs and application of the Au (at) Au (at) Ag / Pt / M NPs in klebsiella pneumoniae detection, and belongs to the technical field of analysis and detection. The invention particularly relates to development of a signal probe and combination and assembly of the signal probe and lateral flow immunochromatography (LFIA) for klebsiella pneumoniae detection. Au (at) Au (at) Ag / Pt / MNPs is a multi-element noble metal nanoparticle with plasma resonance property, peroxidase-like activity and light stability, shows strong detection potential in three modes of colorimetric (CM), catalytic colorimetric (CL) and surface enhanced Raman scattering (SERS), and is loaded into LFIA to construct a multi-mode LFIA (CM / CL / SERS-LFIA). The kit is expected to be used for direct multimode detection of klebsiella pneumoniae in clinical sputum samples, and a new early detection strategy is provided for respiratory tract infection diseases such as klebsiella pneumoniae.

The invention relates to the technical field of water quality detection, in particular to a water quality total chlorine detection method and system.The method comprises the steps that firstly, the influence of environmental conditions on a chromogenic reaction is considered, and the environmental interference degree is determined through the temperature influence degree representing the overall temperature fluctuation change and the pH value influence degree representing the overall pH value standard deviation condition; then determining the chemical interference degree by characterizing the wavelength standard deviation and width of the maximum absorption peak which interferes with the influence of chemical substances and deviates and the number of redundant absorption peaks according to the influence of chemical conditions on the chromogenic reaction; determining a historical measurement error of the water quality total chlorine detector through a control variable method; the corrected water quality total chlorine concentration obtained by correcting the initial water quality total chlorine concentration by means of the environmental interference degree, the chemical interference degree and the measurement error is more accurate, and the accuracy of water quality total chlorine detection according to the obtained water quality total chlorine concentration is higher.

The invention belongs to the technical field of immunodetection, and discloses a rabbit monoclonal antibody mAb6 of an anti-mouse immune globulin G2a subtype (IgG2a) and application thereof. The rabbit monoclonal antibody mAb6 comprises a light chain variable region and a heavy chain variable region, the light chain variable region comprises LCDR1-3, the LCDR1 comprises an amino acid sequence KSVYKNNY, the LCDR2 comprises an amino acid sequence GTN, and the LCDR3 comprises an amino acid sequence AGGYID; the heavy chain variable region comprises HCDR1-3, the HCDR1 comprises an amino acid sequence RFSLSNYR, the HCDR2 comprises an amino acid sequence IFTRGST, and the HCDR3 comprises an amino acid sequence ARGWNS. The rabbit monoclonal antibody disclosed by the invention can be combined with a mouse immune globulin G2a subtype (IgG2a) in a high-specificity manner, can be applied to immunodetection, and provides a basis for further preparation of engineering antibodies.

The invention relates to a double-probe detection reagent for detecting salmonella typhimurium and a preparation method of the double-probe detection reagent, and belongs to the technical field of food safety. The double-probe detection reagent is formed by respectively packaging a magnetic separation probe reagent solution and a fluorescent nano-enzyme probe reagent solution; the magnetic separation probe reagent liquid is used for specifically binding salmonella typhimurium and carrying out separation and enrichment treatment on a detection sample; the red fluorescent nano-enzyme probe reagent solution is used for specifically combining the salmonella typhimurium subjected to separation and enrichment treatment and generating a salmonella typhimurium concentration dependent colorimetric signal and a fluorescent signal. The double-probe detection reagent disclosed by the invention is short in detection time and high in detection sensitivity when being used for detecting salmonella typhimurium, and has relatively good specificity on common type strains. According to the invention, the specific surface area is high, the peroxidase-like activity is excellent, and the high-sensitivity capture efficiency is enhanced; according to the invention, mutual verification is carried out between the dual-mode signals, an internal proofreading effect is achieved, and the detection result is accurate.

The invention discloses a method for detecting antioxidants and polyphenols in food by constructing a colorimetric sensing array based on monatomic iron nano-enzyme, and belongs to the field of nanotechnology and colorimetric sensing. The traditional monatomic nano enzyme shows limited enzyme-like activity and substrate specificity, and is difficult to meet the comprehensive requirements of detecting various antioxidants and polyphenols in food. In the research, a novel nano-enzyme system (sdsFeN (at) G) of monatomic iron nano-enzyme is developed. The SdsFeN (at) G shows excellent enzymatic activity, and a three-channel colorimetric sensing array is constructed by utilizing inhibition of different antioxidants and polyphenols on oxidation of three chromogenic substrates, so that simple, convenient and reliable identification and detection of five substances (tert-butylhydroquinone, butylated hydroxyanisole, propyl gallate, catechol and hydroquinone) in food are realized.

The invention relates to the technical field of organic material detection, in particular to an imine molecular sensor with a five-detection function, two-component gel as well as a preparation method and application of the imine molecular sensor. The imine molecular sensor has three signal responses of fluorescence on-off, ultraviolet absorption and color change to Fe < 3 + >, Co < 2 + > and Ni < 2 + > in a solution state, and has ultraviolet absorption and fluorescence on-off dual-detection performance to acid and alkali changes; the imine molecular sensor and cholesteryl half ester can form two-component gel through a heating-low-temperature ultrasonic cooling method; after Fe < 3 + >, Co < 2 + >, Ni < 2 + >, NaOH and HCl are respectively added, the orange of the gel becomes milky white, reddish brown, transparent red, milky white and milky white under sunlight, and the fluorescence of the orange of the gel disappears under an ultraviolet lamp, so that the rapid and sensitive detection of Fe < 3 + >, Co < 2 + >, Ni < 2 + >, acid and alkali under two states of the imine molecular solution and the gel is realized. The imine molecular sensor provided by the invention has the advantages of mild synthesis conditions, simple preparation and the like, and creates favorable conditions for popularization and application of the imine molecular sensor.

The invention provides a crystalline supramolecular polymer based on snap ring aromatic hydrocarbon. The polymer is obtained by self-assembling snap ring aromatic hydrocarbon (CLP) and a naphthalimide derivative (NDI-8) through a subject and an object. The crystalline supramolecular polymer (NDI-8 (at) CLPalpha) can fully utilize the synergistic effect of a plurality of weak interactions, so that the charge transfer interaction between molecules can be remarkably enhanced very easily. The crystalline supramolecular polymer constructed based on charge transfer shows excellent gasochromic performance. The p-xylene in the NDI-8-coated CLPalpha p-xylene isomer has efficient identification and detection capability, the color is changed from purple to light pink, and a wide application prospect is provided for the development of stimuli-responsive materials.

The invention discloses a micro-reagent ammonia nitrogen on-line continuous analyzer and an analysis method, and belongs to the technical field of water quality ammonia nitrogen monitoring, the micro-reagent ammonia nitrogen on-line continuous analyzer comprises a first injection pump, a second injection pump, a multi-channel valve, a liquid storage ring and a reaction tank; liquid outlets of the first injection pump and the second injection pump are respectively connected with one end of the liquid storage ring and a circulating port of the reaction tank through different channels of the multi-channel valve; a circulating port of the reaction tank is connected with a first peristaltic pump; the other end of the liquid storage ring is connected with a second peristaltic pump; liquid outlets of the first injection pump and the second injection pump are connected with a third peristaltic pump; a first reagent and a second reagent for ammonia nitrogen analysis are respectively stored in the first injection pump and the second injection pump; different channels of the multi-channel valve are respectively connected with a standard sample and a water sample which are used for ammonia nitrogen analysis, and cleaning water. The micro-reagent ammonia nitrogen on-line continuous analyzer provided by the invention can reduce cross contamination of reagents, reduce reagent consumption and realize short-interval continuous analysis.

The invention provides a colorimetric / fluorescent dual-mode sensor, a preparation method of the colorimetric / fluorescent dual-mode sensor and application of the colorimetric / fluorescent dual-mode sensor in histamine detection. The colorimetric / fluorescent dual-mode sensor comprises a horseradish peroxidase-loaded metal organic framework (HRP-AIE-MOF), hydrogen peroxide and a chromogenic substrate o-phenylenediamine (OPD), horse radish peroxidase (HRP) in the HRP-coated AIE-MOF can oxidize colorless OPD into yellow 2, 3-diaminophenazine (DAP), an ultraviolet absorption peak is generated at 425 nm, a strong fluorescence emission peak is generated at 555 nm, the HRP-coated AIE-MOF has a strong fluorescence emission peak at 450 nm, and the HRP-coated AIE-MOF and a fluorescence signal of the DAP can form a ratio fluorescence sensor. According to the invention, the excellent catalytic ability of natural enzyme and the luminescence characteristic of AIE-MOF are integrated in one system, and high-sensitivity histamine detection is realized.

The invention relates to the technical field of bacterium detection, in particular to a colorimetric-Raman coding immunochromatography test strip based on a 3D film-shaped SERS probe and a multi-bacterium detection method thereof. According to the technical scheme, the kit comprises a sample pad, a nitrocellulose membrane, a water absorption pad, a 3D membrane-like SERS probe and an operation buffer solution. According to the present invention, the immunochromatography of the 3D film-like probe is provided, the MoDAu-coated Ag SERS nano-film is adopted as the probe in the system, such that the pathogenic bacteria can be highly specifically recognized and captured, the immune complex fluidity can be increased, the rapid quantitative detection of the three pathogenic bacteria can be achieved, and the flexible 3D film-like SERS probe capable of enhancing the colorimetric ability and the SERS activity and highly specifically capturing the pathogenic bacteria can be prepared; by combining with an antibody-modified ICA test strip, rapid, simultaneous and quantitative determination of various pathogenic bacteria is realized.

The invention provides a hydrogen monitoring sensing mechanism and a hydrogen leakage detection device based on RGB color analysis, and belongs to the field of hydrogen leakage detection. The hydrogen monitoring and sensing mechanism is used for collecting a color signal of the hydrogen-sensitive color-changing adhesive tape and converting the color signal of the hydrogen-sensitive color-changing adhesive tape into an electrical signal, and the hydrogen monitoring and sensing mechanism comprises a light source assembly, a photoelectric sensor and an auxiliary monitoring assembly; the light source assembly is used for irradiating the hydrogen-sensitive color-changing adhesive tape; the photoelectric sensor is used for collecting a color signal of the hydrogen-sensitive color-changing adhesive tape and converting the color signal of the hydrogen-sensitive color-changing adhesive tape into an electrical signal; the auxiliary monitoring assembly is used for increasing the effective monitoring area of the hydrogen monitoring sensing mechanism.

The invention discloses application of iron ruthenium nano-enzyme in preparation of nucleic acid detection products, and belongs to the technical field of biological detection and nano-materials. The RIN has stable peroxidase-like (POD) activity, and can catalyze a chromogenic reaction between 3, 3 ', 5, 5'-tetramethyl benzidine (TMB) and hydrogen peroxide (H2O2). The catalytic activity of the nano-enzyme can be selectively inhibited by pyrophosphate (PPi) generated in a nucleic acid amplification reaction, so that visual colorimetric analysis on whether target nucleic acid exists or not is realized. In combination with a polymerase chain reaction (PCR) system, the invention constructs a new nucleic acid detection strategy which does not need fluorescence labeling, is simple and convenient to operate and has high sensitivity. Through verification, the system can be widely applied to rapid on-site screening and visual interpretation of related nucleic acid of drug-resistant pathogens (such as ESKAPE flora) and the like, and has a good application prospect.

The invention belongs to the technical field of biological medicine, and particularly relates to a kit for breast cancer diagnosis and application thereof. The kit comprises an elisa plate coated with a captured antibody and an HRP labeled antibody working solution, the capture antibody is a monoclonal antibody T2X-1 of an anti-PSTPIP1 protein; the HRP labeled antibody is a monoclonal antibody Z4Y-2 of an anti-PSTPIP1 protein, and the HRP labeled antibody is a monoclonal antibody Z4Y-2 of an The heavy chain amino acid sequence of the monoclonal antibody T2X-1 is as shown in SEQ ID NO.1, and the light chain amino acid sequence of the monoclonal antibody T2X-1 is as shown in SEQ ID NO.2; the heavy chain amino acid sequence of the monoclonal antibody Z4Y-2 is as shown in SEQ ID NO.3, and the light chain amino acid sequence of the monoclonal antibody Z4Y-2 is as shown in SEQ ID NO.4. The kit for breast cancer diagnosis provided by the invention can be used as an auxiliary diagnosis means for breast cancer with high expression of PSTPIP1 protein, and has high diagnostic value.

The invention provides a peritoneal dialysis solution detection data intelligent analysis method based on visual identification, and the method comprises the steps: obtaining a to-be-identified test paper image, carrying out the test paper region segmentation and color correction of the test paper image, and carrying out the brightness equalization processing of a test paper detection region, and obtaining a processed test paper detection region; obtaining a standardized color feature vector of a test paper color development area from the test paper detection area; carrying out mapping matching on the standardized color feature vector and a standard colorimetric database to obtain a colorimetric matching value, carrying out color abnormality identification according to the colorimetric matching value, comparing the color abnormality with a preset abnormal value to obtain a test paper colorimetric analysis result, and carrying out self-adaptive correction on the test paper colorimetric analysis result with abnormality; and constructing a personalized colorimetric model according to the colorimetric matching value in combination with a historical colorimetric matching value, and performing health trend analysis and early warning.

Devices, systems, and methods may include or use a fixed imaging system with a window defining a window plane and an image sensor proximal of the window plane. The fixed imaging system may include or may be used with an optical relay positioned between the window plane and an object plane. The fixed imaging system may be configured to capture an image of an object at the object plane along an optical path through the window plane and the optical relay. The object may be a reactant array, which may be on a substrate. A housing may be configured to receive the substrate and position the reactant array at the object plane.