3201 results about "Working electrode" patented technology

Methods and analyte sensors including at least a first working electrode having a first active area thereon, and performing a dip coating operation to deposit a bilayer membrane upon the first working electrode and the first active area. The bilayer may include an inner layer having a first membrane polymer and an outer layer having a second membrane polymer, the first membrane polymer and the second membrane polymer differing from one another. The dip coating operation may comprise one or more first dips in a first membrane formulation to form the inner layer of the bilayer membrane and one or more second dips in a second membrane formulation to form the outer layer of the bilayer membrane upon the inner layer.

Embodiments described in this application relate generally to a system, an apparatus and / or methods for manufacturing electrodes by infusion electrolyte into compacted electrode materials. In some embodiments, a working electrode materials can be produced using an infusion mixing and manufacturing process. In some embodiments, a single-sided finished electrode can be produced directly from a dry powder mixture using an infusion mixing and manufacturing process. In some embodiments, a double-sided finished electrode can be produced directly from a dry powder mixture using an infusion mixing and manufacturing process. The electrodes produced by an infusion mixing and manufacturing process generally perform better than those produced by non-infusion processes.

Described herein are variations of an analyte monitoring system, including an analyte monitoring device. For example, an analyte monitoring device may include a skin-penetrating microneedle array for use in measuring analyte, such as in a continuous manner. The microneedle array may include, for example, at least one microneedle comprising a working electrode comprising an analyte-sensing aptamer that selectively and reversibly binds to analyte. The working electrode comprises at least one thiol-based passivation molecule that provides protection of the working electrode from, by way of example, foulants and interferents. For example, a sensor may be configured to generate a signal that is indicative of a concentration of an analyte in a fluid, the sensor comprising a working electrode comprising an electrode material, a biorecognition layer disposed at least partially on the electrode material and comprising a biorecognition element that selectively and reversibly binds to an analyte, and an at least partially desiccated hydrogel disposed on the biorecognition layer. For example, a working electrode may be configured to generate a signal indicative of a concentration of an analyte in a fluid, the working electrode comprising an electrode material, a biorecognition element disposed on the electrode material that selectively binds to the analyte, wherein the biorecognition element is functionalized with a redox-active molecule and is configured to change conformation upon binding the analyte to move the redox-active molecule, closer to, or further from, the electrode material, and a passivation element comprising a zwitterionic peptide disposed on the electrode material.

Methods and analyte sensors including at least a first working electrode having a first active area thereon, and performing a dip coating operation to deposit a bilayer membrane upon the first working electrode and the first active area. The bilayer may include an inner layer having a first membrane polymer and an outer layer having a second membrane polymer, the first membrane polymer and the second membrane polymer differing from one another. The dip coating operation may comprise one or more first dips in a first membrane formulation to form the inner layer of the bilayer membrane and one or more second dips in a second membrane formulation to form the outer layer of the bilayer membrane upon the inner layer.

Methods and analyte sensors including at least a first working electrode having a first active area thereon, and performing a dip coating operation to deposit a bilayer membrane upon the first working electrode and the first active area. The bilayer may include an inner layer having a first membrane polymer and an outer layer having a second membrane polymer, the first membrane polymer and the second membrane polymer differing from one another. The dip coating operation may comprise one or more first dips in a first membrane formulation to form the inner layer of the bilayer membrane and one or more second dips in a second membrane formulation to form the outer layer of the bilayer membrane upon the inner layer.

The invention relates to a flexible electrochemical pH sensor as well as a preparation method and application thereof. Wherein the flexible electrochemical pH sensor comprises a flexible nanofiber substrate as well as a working electrode and a reference electrode which are arranged on the surface of the flexible nanofiber substrate at an interval, the working electrode comprises a first working part and a first wire part connected with the first working part, and the first working part is provided with a polyaniline sensitive layer. The flexible electrochemical pH sensor has the characteristics of high sensitivity, good flexibility and good air and moisture permeability, can be tightly attached to the surface of skin to monitor the pH value of body fluid, and is high in monitoring accuracy and simple in manufacturing method.

The invention discloses a multifunctional interlayer modified silicon-based nanowire photoelectric cathode, which comprises a p-Si substrate layer, a nanowire morphology layer, a CdS layer and a MoS2 cocatalyst layer, the preparation method comprises the following steps: (1) cleaning the p-Si substrate, and blow-drying the p-Si substrate for later use; (2) depositing in a first deposition solution to prepare a p-Si substrate with silver particles adsorbed on the surface; (3) etching in an etching solution, and forming a nanowire structure on the p-Si substrate; (4) placing the nanowire structure in a second deposition solution for deposition, and forming a CdS layer on the nanowire structure; and (5) taking the p-Si substrate treated in the step (4) as a working electrode, and depositing in an electro-deposition solution to prepare the silicon-based nanowire photoelectric cathode. The CdS layer and the MoS2 co-catalyst layer in the photoelectric cathode reduce the lattice mismatch problem caused by direct loading of the CdS layer and the MoS2 co-catalyst layer, and meanwhile, the CdS layer and the MoS2 co-catalyst layer and the silicon substrate form a heterogeneous pn junction structure, and the photoelectrochemical performance is remarkably improved through a multi-layer synergistic effect.

Methods and analyte sensors including at least a first working electrode having a first active area thereon, and performing a dip coating operation to deposit a bilayer membrane upon the first working electrode and the first active area. The bilayer may include an inner layer having a first membrane polymer and an outer layer having a second membrane polymer, the first membrane polymer and the second membrane polymer differing from one another. The dip coating operation may comprise one or more first dips in a first membrane formulation to form the inner layer of the bilayer membrane and one or more second dips in a second membrane formulation to form the outer layer of the bilayer membrane upon the inner layer.

Disclosed are devices, systems and methods for in vivo monitoring of localized environment conditions within a patient user by measuring analytes, including glucose, oxygen, and / or other analytes. In some aspects, a sensor device includes a wafer-based substrate, at least one electrochemical sensor two-electrode contingent including a working electrode and a reference electrode on the substrate and configured to detect a target analyte in a body fluid when the sensor device is deployed within a subject's body, where the working electrode is functionalized by a chemical layer configured to facilitate a reaction involving the target analyte that produces an electrical signal; and an electronics unit in communication with the electrochemical sensor electrode contingent to transmit the electrical signal to an external processor.

Disclosed herein are systems and methods for electrically modulating tissue. Systems can include a current generator; at least one implantable working electrode, the at least one implantable working electrode configured to be in electrical communication with the current generator; at least one indifferent electrode; and a controller configured to signal the current generator to: generate a set of currents with a set of initial polarities to be delivered to the working electrodes; and wherein the at least one indifferent electrode absorbs a bias current which is equal in magnitude and opposite in polarity to a summation of the set of currents.

The invention discloses an electrochemical sensor constructed based on a composite material and a preparation method and application thereof.The electrochemical sensor comprises a screen-printed electrode, the surface of the reaction end of a working electrode of the screen-printed electrode is loaded with a zirconium-based metal organic framework composite material, the composite material comprises UiO-66, and the surface of the composite material is modified with a polydopamine coating. The preparation method comprises the following steps: preparing the zirconium-based metal organic framework composite material and fixing the composite material on the working electrode of the screen-printed electrode. According to the invention, the zirconium-based metal organic framework composite material with many adsorption sites, good dispersibility, good conductivity and good hydrophilicity is used as a functional material, so that the sensor has the advantages of simple operation, low cost, rapid response, strong anti-interference capability, wide detection linear range, high detection sensitivity, long service life and the like, and can be widely used for detecting Mn < 2 + >, Mn < 2 + >, Mn < 2 + >, Mn < 2 + > and Mn < 2 + > in a water body. The method can realize rapid and accurate detection of Mn < 2 + > in a water body, and is high in use value and good in application prospect.

The present invention discloses a self-supporting flexible carbon material and its preparation method and application. It comprises the following steps: (1) using carbon felt as a working electrode and a counter electrode respectively, applying electricity in an electrolyte for 2 to 10 minutes, washing and drying, and obtaining an electrochemically stripped carbon felt; (2) using a mixture of nitrogen-containing conductive polymer monomers and alkaline solution as an electrolyte, and using the carbon felt treated in step (1) as a working electrode to construct a three-electrode system for electrochemical treatment, washing and drying, and obtaining a carbon felt loaded with a nitrogen-containing conductive polymer; (3) heat treating the carbon felt obtained in step (2) at 800 to 900°C in a protective gas atmosphere for 1 to 2 hours, cooling to room temperature, and then washing and drying. The present invention can simultaneously complete the two steps of element doping and activation through a one-step high-temperature process, and the prepared flexible carbon material has excellent electrochemical properties.

The invention discloses a wearable sweat glucose detection system based on multi-shell metal organic framework encapsulated enzyme and a preparation method of the wearable sweat glucose detection system. The detection system comprises a sweat collection and sensing module, an electrochemical detection module and an iontophoresis module, the sweat collecting and sensing module comprises a micro-fluidic channel and a screen-printed electrode; the micro-fluidic channel is used for collecting sweat; the screen-printed electrode comprises a working electrode for detecting glucose, a counter electrode and a reference electrode to form a three-electrode system; wherein the working electrode for detecting the glucose is provided with a functional layer, and the functional layer is modified by multi-shell metal organic framework layered encapsulation enzyme for detecting the glucose and chitosan for fixing the multi-shell metal organic framework layered encapsulation enzyme; the electrochemical detection module is used for obtaining electrochemical sensing detection data; and the iontophoresis module is used for outputting an adjustable constant current source to enable iontophoresis to stimulate skin to sweat. The portable long-time continuous detection of sweat glucose can be realized, and the detection method is rapid and convenient.

The invention provides a NiCo double hydroxide self-supporting nano-catalyst as well as a preparation method and application thereof, and belongs to the field of nano composite materials. The preparation method of the NiCo double hydroxide self-supporting nano-catalyst is characterized by comprising the following steps: firstly, adding cobalt salt and nickel salt into a solvent, performing ultrasonic treatment to completely dissolve the two metal salts to obtain a metal salt solution, and then assembling a working electrode, a counter electrode and a reference electrode in the metal salt solution to obtain a three-electrode device, and finally, adjusting corresponding parameters in an electrochemical workstation, and carrying out a self-supporting deposition experiment of Ni and Co double-metal hydroxides on the three-electrode device in the electrochemical workstation to obtain the NiCo double-metal hydroxide self-supporting nano-catalyst material with a typical scaly structure and excellent performance. According to the preparation method of the NiCo double-metal hydroxide self-supporting nano-catalyst material, product treatment is convenient and fast, and the process is simple.

The invention provides a metal particle loaded self-supporting electrode material and a preparation method and application thereof, and belongs to the technical field of battery electrodes, the preparation method comprises the following steps: S1, cutting beech into pieces with the thickness of 5-7mm along the vertical growth direction, and calcining to obtain carbonized wood pieces; s2, metal salt is dissolved in the functionalized aqueous solution, the concentration of the metal salt is 0.03-0.05 M, and a soaking solution is obtained; the functionalized aqueous solution comprises dodecyl trimethyl ammonium chloride, sodium pyrophosphate, polyvinylpyrrolidone and water; s3, taking the carbonized wood chip as a working electrode, immersing the carbonized wood chip into the soaking solution, carrying out electro-deposition on a metal precursor, and then cleaning and drying to obtain a metal-loaded wood chip; and S4, pyrolyzing the metal-loaded wood chip in a hydrogen-argon mixed atmosphere, then cooling to room temperature, cleaning and drying to obtain the metal-loaded wood chip. According to the invention, the transition metal particles and the carbonized wood chips are better compounded, and more reliable active sites are provided for bromine electrochemical reaction, so that the overall performance of the zinc-bromine battery is improved.

The present invention relates to: an electrochemical biosensor capable of effectively and sensitively detecting alfuzosin; an electrode applied thereto; a metal-organic framework (MOF) which includes a zinc / cobalt oxide and is applied in manufacturing the electrode; and methods for manufacturing same.

The invention discloses a method for synthesizing deuterated olefin under catalysis of a palladium membrane by taking D2O as a deuterium source, and belongs to the technical field of synthesis of deuterated olefin building blocks. According to the method, a three-chamber electrolytic tank separated by a palladium membrane and an ion exchange membrane is used as a reactor, the palladium membrane is used as a working electrode, an electrolyte deuterium aqueous solution is used as an electrolyte, deuterium water is electrolyzed through a constant-potential electrolysis method, and formed active deuterium is transmitted to one side of an organic reaction taking absolute ethyl alcohol or cyclohexane as an organic solvent; and catalyzing an alkyne compound by using a palladium membrane modified by sodium thiophenol to perform reduction deuterization so as to synthesize a deuterated olefin compound with high selectivity, and further synthesizing a corresponding deuterated drug. The invention provides a green, efficient, high-universality and low-cost amplification synthesis method for synthesizing a deuterated olefin building block containing a functional group easy to reduce and hydrolyze, and the method has a wide application prospect.

The invention discloses a potassium ion sensor based on AuNPs / MXene / SPCE and a preparation method thereof, and belongs to the technical field of electronic components. Comprising a screen-printed carbon electrode SPCE, an MXene layer modified on the surface of a working electrode of the screen-printed carbon electrode, a gold nanoparticle AuNPs layer formed on the surface of the MXene layer through an electrochemical deposition method, a potassium ion selective membrane covering the gold nanoparticle AuNPs layer, and a GO-PVA hydrogel layer coating the surface of the potassium ion selective membrane. According to the prepared sensor, only potassium ions in sweat can pass through the selective membrane, the selectivity of the sensor is improved, meanwhile, due to the application of the AuNPs / MXene composite material, the surface area-volume ratio of a silk-screen printing carbon electrode is greatly improved, more potassium ions participate in ion-electron conversion, the sensitivity of the sensor is improved, and the application range of the sensor is widened. And the detection range is expanded.

The invention discloses a preparation method of a bionic cornea stroma lens for refractive correction, which comprises the following steps: solution preparation: dissolving type I collagen in an acetic acid solution, adding a film aid, fully stirring, and centrifugally defoaming to obtain a type I collagen composite solution; the I-type collagen composite solution is poured into an assembling groove, the curvature radius of titanium metal is set to be 6.8-8.0 mm, the titanium metal serves as a working electrode material, platinum metal serves as a counter electrode material, current parameters are set according to the needed thickness of the lens blank, the density is 3.50-6.50 mA / cm < 2 >, and the thickness of the lens blank is set to be 3.50-6.50 mA / cm < 2 >; a high-transparency cornea embryo material which is uniform in curvature in all directions and similar to human cornea fiber structure arrangement is formed after electrochemical assembly and cross-linking curing, accurate cutting machining is carried out through excimer laser, a concave / convex matrix lens with the needed correction degree is obtained, the correction precision is high after cornea interlayer implantation, and the correction precision is high. And meanwhile, the compound has excellent performance in the aspects of in-vivo stability and biological safety.

The invention provides an MEMS electrochemical gas sensor and a processing method thereof. The sensor is mainly composed of a breathable substrate structure, a counter electrode, a semi-solid electrolyte layer and a working electrode, the counter electrode, the semi-solid electrolyte layer and the working electrode form a sandwich structure, the thickness of the semi-solid electrolyte layer is 1-30 microns, and the semi-solid electrolyte layer is mainly of a film structure formed by baking a semi-solid electrolyte solution. According to the MEMS electrochemical gas sensor, the semi-solid electrolyte layer is mainly processed based on a semi-solid electrolyte material by adopting processes such as spraying or spin-coating, drying and curing, and the MEMS electrochemical gas sensor is designed and prepared by combining an MEMS process, so that the size of the sensor structure can be 1 mm, the miniaturized and zero-power-consumption work is realized, the gas sensor has a good response signal, and the gas sensor has a good application prospect. The load resistance is in a kiloohm level, and the output current is in a [mu] A level. The sensor can be used for monitoring reducing gases such as carbon monoxide, ethanol, formaldehyde and the like.

The present application provides a sensor device and related methods for electrochemically measuring a substance in a fluid, particularly a bodily fluid, wherein said sensor device comprises one or more electrodes, wherein said one or more electrodes comprise at least a working electrode, a reference electrode and / or a counter electrode, wherein the surface of at least the working electrode is coated with a crosslinked polymer, such as a crosslinked chitosan, a crosslinked PEI, a crosslinked polylysine, and the like. In particular embodiments, the sensor device may comprise a microneedle array comprising a plurality of microneedle electrodes, wherein at least the working microneedle electrode is coated with a crosslinked polymer. The present application further provides a system and related methods for the monitoring of a first substance and delivery of a second substance in the dermal interstitial fluid of a subject, wherein the system comprises the sensor device and a drug delivery system.

The invention provides a preparation method of a nickel-based composite oxygen evolution anode for alkalescent electrolyte. According to the invention, nickel-based alloy is used as substrates, two same substrates are respectively used as a working electrode and an auxiliary electrode, two-electrode system electrochemical oxidation reduction treatment at room temperature is carried out in a mixed solution of phosphate, carbonate and chloride, and two reconstructed nickel-based composite oxygen evolution electrodes are obtained at the same time. In the electrochemical oxidation process, nickel ions and other metal (Fe, Co, Cr and Mn) ions are dissolved out from the nickel-based alloy under the etching assistance of chloride ions; in the electrochemical reduction process, water on the electrode is reduced to form hydroxyl. Under continuous oxidation reduction, substance reconstruction is carried out to generate a composite catalyst layer of phosphate, carbonate and hydroxide of nickel and other metals, so that not only can the oxygen evolution activity be improved, but also metal dissolution and corrosion passivation when the catalyst is used in a weakly alkaline solution can be inhibited, and the durability of the electrode is greatly improved.

The invention discloses a method for detecting cadmium ions and lead ions in a water body by utilizing a screen-printed electrode electrochemical sensor, which comprises the following steps of: constructing the screen-printed electrode electrochemical sensor by taking a screen-printed electrode of which the surface of a reaction end is modified with a ZIF-8 / MWCNT nano composite material as a working electrode; the method comprises the following steps: detecting the peak current change of a to-be-detected cadmium / lead ion solution by using a screen-printed electrode electrochemical sensor, and calculating the concentrations of cadmium ions and lead ions in the to-be-detected cadmium / lead ion solution by using a linear regression equation of the cadmium ion concentration, the lead ion concentration and the peak current change. The method provided by the invention has the advantages of simple operation, low cost, high detection efficiency, high detection accuracy and the like, can realize on-site detection of cadmium ions and lead ions in a water body, and has the advantages of convenient operation, high accuracy, strong anti-interference capability to interference factors, and good application prospect. The method is of great significance to efficient detection of heavy metal cadmium ions and lead ions in the water environment.

A carbon dioxide recovery system includes an electrochemical cell that includes a working electrode, a counter electrode, an insulating layer, and an electrolyte layer. The electrochemical cell is configured to repeat an adsorption mode and a desorption mode. In the adsorption mode, in a state where oxygen is supplied together with a gas to be treated that contains carbon dioxide to a portion of the electrolyte layer in a vicinity of the working electrode, a voltage is applied between the working electrode and the counter electrode to supply electrons to the working electrode so that the oxygen receives electrons to generate active oxygen, and the active oxygen combines with the carbon dioxide to absorb the carbon dioxide and generate a carbon dioxide adsorbed molecule.

The invention belongs to the technical field of electrochemical sensors, and particularly relates to a thin-layer channel electrochemical sensor for online detection of available chlorine concentration, the thin-layer channel electrochemical sensor comprises a butt joint seat, a reference electrode module, a working electrode module, an acid path cleaning assembly and an alkali path cleaning assembly, and the alkali path cleaning assembly is located right below the acid path cleaning assembly. In order to solve the problems that in the prior art, after a working electrode and a reaction cup are cleaned, electrolyte needs to be added again, the whole process is tedious, a large amount of electrolyte needs to be consumed, the detection efficiency and speed are reduced, and meanwhile the detection cost is increased, through cooperation of an acid path cleaning assembly and an alkali path cleaning assembly, the detection efficiency is improved; according to the cleaning device, cleaning and impurity removal can be carried out without disassembly, the total time required by continuous detection is shortened, so that the detection efficiency is improved, meanwhile, a worker can select different cleaning modes according to the actual detection frequency, and the working efficiency is improved.

The invention relates to the technical field of electrochemical sensors, and provides a multi-channel electrochemical detection electrode, an electrochemical sensor and a detection method.The multi-channel electrochemical detection electrode comprises an electrode substrate and a plurality of working electrodes arranged on the electrode substrate; the surfaces of the plurality of working electrodes are respectively modified with different types of metal nano-catalysts to detect different gas components, and the surfaces of the working electrodes are covered with PDMS hydrophobic layers to form a hydrophilic / hydrophobic channel separation structure. The surfaces of a plurality of working electrodes are modified with different types of metal nano-catalysts and covered with PDMS hydrophobic layers to form a hydrophilic / hydrophobic channel separation structure, and the multi-channel electrochemical detection electrode separates gas molecules through hydrophilic / hydrophobic channels, so that the cross reaction can be inhibited, and the cross sensitivity can be reduced.

The open type in-situ electrochemical reaction tank comprises a reaction tank main body and a connecting assembly, an open type electrolyte cavity is arranged above the reaction tank main body, and a base for mounting a working electrode is arranged below the reaction tank main body; a through objective lens hole is formed between the electrolyte cavity and the base, and a reference electrode jack is formed in the side wall of the electrolyte cavity; a working electrode lead hole is formed in the side wall of the base, and an O-shaped gasket groove, a silica gel gasket groove and a working electrode fixing screw hole are formed in the bottom of the base. The reaction tank disclosed by the invention can realize in-situ electrochemical spectrum detection by connecting an electrochemical workstation, is small in volume, simple in mounting method, convenient to clean, high in quality of collected spectrum signals, acid-base-resistant and wide in application range, not only can be adaptive to upright and inverted micro-Raman spectrum systems, but also can ensure the accuracy of electrochemical spectrum test, and is suitable for large-scale popularization and application. The reaction mechanism can be deeply understood, the reaction conditions can be optimized, and the research quality can be improved.

A working electrode is inserted into the plant to monitor the health of the plant components or to detect physical, mechanical damage or environmental change in the soil or atmosphere. A standard electrode is inserted into soil surrounding the plant or in the plant itself. A data logger connects the working electrode and the standard electrode. The data logger measures the potential difference between the working electrode and the electrolyte to provide the ability to compare a measured potential difference with a predetermined critical potential difference for the plant. A second electrochemical cell can inject electrons and ions into the plant. The plant can be used as a sensor to monitor the environmental change in the soil or in the atmosphere.

An intelligent deformable microneedle includes a supporting seat; a counter electrode provided above the supporting seat; an elastic object with a compressed state and a natural state, where a working electrode is provided on an outer surface of the elastic object, and a specific enzyme that can react with an analyte to be detected is provided on the working electrode; a soluble needle-shaped body fixed on the supporting seat, where the soluble needle-shaped body completely wraps the counter electrode and the elastic object from the outside, and the soluble needle-shaped body has an inner cavity structure that enables the elastic object to be in the compressed state. The microneedle is internally provided with the elastic object, after penetrating into skin, the soluble needle-shaped body is dissolved, the elastic object inside is exposed, length becomes longer, and the working electrode of an electrochemical sensor is attached to the elastic object.

The invention discloses a method for measuring the mass sensitivity of a quartz crystal microbalance with asymmetric electrode configuration, which comprises the following steps of: placing an upper electrode of the quartz crystal microbalance with asymmetric electrode configuration as a working electrode of a three-electrode electrochemical electroplating system in electroplating liquid; the asymmetric electrode configuration quartz crystal microbalance is connected into a frequency measurement system, so that a three-electrode electrochemical electroplating measurement system is constructed, and the increased mass of an electroplated film can be obtained only by measuring the total charge amount. The problem that the mass sensitivity of the asymmetric electrode configuration QCM sensor cannot be calculated by the existing Sauerbrey theory is solved, meanwhile, the measurement of the total charge belongs to electronic measurement, the measurement accuracy is far greater than the measurement accuracy of salt solution parameters, and only one electrical parameter is measured, so that the measurement accuracy of the mass sensitivity of the QCM sensor is greatly improved, and the measurement accuracy of the mass sensitivity of the asymmetric electrode configuration QCM sensor is greatly improved. The method has a wide application prospect, and can be popularized to solve the problem of experimental measurement of overtone quality sensitivity.