The invention provides a pulse wave array sensor acquisition system and method. The acquisition system comprises multiple piezoelectric film sensors. The piezoelectric film sensors are PVDF film sensors arranged in an array mode and are used for converting pulse pressure signals into voltage signals. Array PVDF piezoelectric films are adopted in the acquisition system, the piezoelectric constant is large, variable force response sensitivity is high, the films are light and flexible, preparation is easy, impedance coupling with human tissue is good, mechanical quality factors are low, resistance is low, density is low, and the frequency characteristics of the pulse signals can be met. In addition, the acquisition system can guarantee that information of three positions of cun, guan and chi is completely acquired, more accurate positioning can be achieved, and artificial errors are eliminated. Gradual pressurized measurement can be conducted on wrist positions, and the problems that existing pulse sensors hardly conduct positioning and calibrate floating, centering and sinking are effectively solved. Circuits are simplified, and miniaturization of the circuits can be achieved.