430results about "Nanomagnetism" patented technology

Microparticles for detecting biological materials are provided. Each of the microparticles includes: a core-shell structured microparticle consisting of a core including a magnetically responsive metal and a shell layer surrounding the core and having a uniform thickness; and capture probes introduced onto the shell layer to capture biological materials.

This disclosure provides nanoparticle compositions, and use thereof for isolating and measuring proteins, protein degrader action, and cells. The disclosed nanoparticles can be identified by barcodes that reveal the identity of and post translational modifications to the bound protein using image processing techniques described herein.

Described herein are compositions, systems, and methods for targeted and controlled drug release. In some embodiments, the compositions, systems, and methods may comprise magnetoelectric silica nanoparticles for targeted and controlled release of chemotherapeutic drugs for cancer treatment. In some embodiments, an external magnetic field may be used to release one or more drugs from the magnetoelectric silica nanoparticles. The disclosed compositions, systems, and methods may improve drug targeting and reduce systemic drug toxicity.

A raw material solution containing trivalent iron ions, or trivalent iron ions and ions of a metal element that partially substitutes Fe sites, and an alkaline aqueous solution for neutralizing the raw material solution are added to a reaction system to adjust the pH of the reaction system from 1.0 to 3.0 or lower. Hydroxycarboxylic acid is added to the obtained reaction solution and the pH of the reaction system is then neutralized from 7.0 to 10.0 or lower. The obtained precipitate of a substituent metal element-containing iron oxyhydroxide is coated with silicon oxide, followed by heating so as to form particles of ε-iron oxide in which Fe sites are partially substituted by other metal elements, and then, a slurry containing the particles is classified. The iron-based oxide magnetic powder has a particle shape close to a perfect sphere and is suitable for use in a magnetic recording medium.

The invention discloses pancreatic lipase immobilized composite nano magnetic beads, a preparation method and application, ferroferric oxide is adopted as a magnetic core, dopamine-mediated growth is performed to form a core-shell structure, then the periphery of the core-shell structure is wrapped with a metal organic framework to form the composite nano magnetic beads, and pancreatic lipase is immobilized by using the composite nano magnetic beads as an adsorption carrier. The enzyme loading amount, the repeated utilization rate and the storage stability of the ferroferric oxide nano-particles are remarkably improved, the enzyme immobilization efficiency and the enzyme activity are improved, and meanwhile, the prepared pancreatic lipase immobilized composite nano-magnetic beads have excellent stability and biocompatibility, are green and pollution-free and can be repeatedly used; the composite nano magnetic beads are synthesized by adopting a solvothermal method, the product is easy to separate, the synthesis process is simple, the enzyme immobilization efficiency can be regulated and controlled by regulating and controlling the synthesis process, the structure of an active ligand can be screened and analyzed from natural products with numerous and jumbled components, and the active ligand has a certain lipid-lowering potential and can be used for preparing the nano magnetic beads. The compound can be used as a potential lead compound of lipid-lowering drugs.

The present disclosure provides a method for preparing a high-purity powder material, an application thereof, and a double-phase powder material. The high-purity powder material is prepared through an “atomization comminuting process and de-phasing method”. The preparation method comprises the following steps: firstly preparing intermediate alloy powders with first-phase particles wrapped by a second-phase matrix through an atomization comminuting process. Impurity elements are enriched into the second-phase matrix and the first-phase particles are purified during the solidification of the intermediate alloy powders; By removing the second-phase matrix in the intermediate alloy powders, a high-purity target powder material originated from the original first-phase particles can be obtained. The preparation method of the present disclosure has the characteristics of a simple process, easy operation, and low cost, and can be used to prepare nano-level, sub-micron-level, and micro-level multiple high-purity powder materials, which has a good application prospect in catalytic materials, powder metallurgy.

The application relates to a method for one-step synthesis of strong magnetic hydrophobic Fe3O4 nanoparticles at low temperature and the Fe3O4 nanoparticles and application, and belongs to the technical field of nano material preparation. The method comprises the following steps: adding a ferrous sulfate solution into a mixed solution of sodium hydroxide and sodium nitrate, heating and stirring to react, adding oleic acid in the reaction process, and obtaining black Fe3O4 crystals after the reaction is completed. The saturation magnetization of the obtained strong magnetic hydrophobic Fe3O4 nanoparticles can reach 85.69 emu / g at most, and the water contact angle can reach 148.95 DEG. The one-step synthesis reaction only needs to use oleic acid as a regulator, avoids an extreme high-temperature and high-pressure environment, does not need to use a toxic chemical solvent, the condition is mild, the process is simple, the operation condition is easy to control, and the method has a wide application prospect.

A magnetic tunneling junction (MTJ) device structure and the method of constructing such device are disclosed. Also disclosed are methods of using the device for spin-dependent transport characterization through biomolecules for structure and dynamic function analysis in physiological environments.

Systems and methods for automated sample preparation and processing of protein corona are described herein, as well as its application in the discovery of advanced diagnostic tools as well as therapeutic agents.

The invention relates to the technical field of comprehensive development and utilization of lignosulfonate and development of novel anti-electromagnetic radiation materials, and discloses a preparation method and application of a biochar / CoFe2O4 dual-loss anti-electromagnetic radiation material. Firstly, iron ions and cobalt ions are adsorbed in a molecular structure of sodium lignosulfonate through electrostatic attraction; then, the biochar / CoFe2O4 composite material is prepared through a high-temperature carbonization treatment one-step method. The anti-electromagnetic radiation material prepared by the invention has both electrical loss and magnetic loss, and has better anti-electromagnetic radiation performance. Lignosulfonate used in the preparation method is low in price and easy to obtain, complex processes and use of a large amount of solvents are avoided in the material preparation process, and the method is economical and environmentally friendly.

Disclosed are a room-temperature and ambient-pressure superconducting ceramic and methods for producing the same. The superconducting ceramic is represented by Formula 1: A10-xBx(PO4)6O wherein A is Ca, Ba, Sr, Sn or Pb, B is Cu, Cd, Zn, Mn, Fe, Ni or Ag, and x is 0.1 to 2.0. The superconducting ceramic exhibits superconductivity at room temperature and ambient pressure. The methods are suitable for producing the superconducting ceramic.

The disclosure relates to a system (100) for removing heat from a battery pack (102). The system (100) includes a cooling jacket (104) defining a flow path corresponding to an arrangement of battery cells in the battery pack (102), and a ferrofluid coolant configured to flow within the cooling jacket (104) along the flow path. The system (100) further includes a plurality of temperature sensors (106), each positioned in a region associated with a set of cells of the battery pack (102), and configured to detect a temperature of the region. The system (100) further includes a plurality of electromagnets (108), each associated with a temperature sensor, and configured to be activated based on a temperature detected by the associated temperature sensor. Activation of an electromagnet causes movement of the ferrofluid coolant towards the region in which the associated temperature sensor is positioned.

A method of assembling a chiral superstructure includes applying a quadrupole magnetic field to a plurality of magnetic nanostructures and configuring the plurality of magnetic nanostructures into a chiral superstructure by controlling a magnitude and a direction of the quadrupole magnetic field. A magnetic chiral superstructure includes a plurality of magnetic nanostructures assembled into a chiral superstructure by applying a quadrupole magnetic field to the plurality of magnetic nanostructures and configuring the plurality of magnetic nanostructures into a chiral superstructure by controlling a magnitude and a direction of the quadrupole magnetic field.

The invention discloses a method for preparing high-zirconium-content silicon carbide from lignite, and relates to a preparation method of high-zirconium-content silicon carbide. The invention aims to solve the problems of non-uniform product distribution and poor performance improvement effect caused by the fact that zirconium compounds are introduced by adding the zirconium compounds into existing silicon carbide in the later period. The method comprises the following steps: 1, preparing a zirconic acid organic matter solution; 2, uniformly mixing a silicon source and lignite powder, adding the mixture into the zirconic acid organic matter solution, quickly adding deionized water, and stirring and reacting at room temperature; 3, high-temperature calcination; 4, removing carbon; and 5, grinding, sieving and carrying out ultrasonic treatment. The method is used for preparing the high-zirconium-content silicon carbide from the lignite.

A semiconductor process integrates three bridge circuits, each include magnetoresistive sensors coupled as a Wheatstone bridge on a single chip to sense a magnetic field in three orthogonal directions. The process includes various deposition and etch steps forming the magnetoresistive sensors and a plurality of flux guides on one of the three bridge circuits for transferring a "Z" axis magnetic field onto sensors orientated in the XY plane.

[Problem] To electrically connect a lead layer and a protective film reliably even when the film thickness of a protective film that covers a functional film is extremely thin. [Solution] After the conductive protective film 51 is formed on the surface of the functional film 20, reverse sputtering is performed while a portion of the surface of the protective film 51 is covered with a mask 60, thereby physically restoring a natural oxide film 52 formed on the surface of the protective film 51 not covered by the mask 60. Thereafter, a lead layer 40 is formed on the surface of the protective film 51 not covered by the mask 60. Consequently, since the natural oxide film 52 formed on the surface of the protective film 51 can be removed without performing etching, the lead layer 40 and the protective film 51 can be connected electrically without damaging the functional layer 20 even when the film thickness of the protective film 51 is extremely thin.

A computing element is provided. The computing element includes a) an artificial lattice comprising a multiplicity of connecting elements separated by pores; b) a plurality of input channels attached to the artificial lattice each configured to provide at least one of an electrical current and voltage to the artificial lattice; c) a plurality of readout channels attached to the artificial lattice, wherein each readout channel of the plurality of readout channels is connected to a common ground; and d) one or more sensing elements positioned at least one of perpendicular and along to the plurality of input channels and attached to the artificial lattice, wherein the one or more sensing elements configured to read a readout to create an output.

The application discloses doped modified manganese iron phosphate with a nanoporous structure, a preparation method and application thereof. 1‑a‑b Fe a M b PO4, 0.01<=a<=0.98, 10 ‑4 <=b<=10 ‑2 M is a combination of one or more selected from magnesium, titanium, vanadium, chromium, cobalt, nickel, zinc, gallium, aluminum, zirconium, niobium, molybdenum, tin, antimony, calcium, barium, strontium, boron, ruthenium, silicon, tellurium, copper and lithium, and the particle size is below 50 nm, and the material also has a porous structure. The material can be used for preparation of lithium manganese iron phosphate positive electrode materials in lithium ion batteries, and the specific capacity, rate and cycle performance of the obtained positive electrode materials are improved.

A bi-phased approach between good solvents (or non-polar) and bad solvents (polar) can be used to assemble nanorods into highly ordered monolayers or multilayers of ordered nanorod arrays. These ordered nanorod arrays can display unique optical properties. For example, ordered arrays of CdSe / CdS core / shell nanorods were assembled that display polarized photoluminescence.

This invention belongs to the field of tertiary oil recovery technology, specifically relating to a CO2-switched magnetically driven nanoparticle, its preparation method, and its application. The magnetically driven nanoparticles are silica-coated Fe3O4 nanoparticles. The surface of the silica coating is further modified with amidine groups to act as CO2 switches. These CO2 switches cause the hydrophilicity of the magnetically driven nanoparticles to increase with the increase of CO2 solubility in the solution in which they are located. This invention integrates emulsification and demulsification functions through the CO2 switch loaded on the surface of the magnetically driven nanoparticles. Furthermore, the particles can be recycled using their own magnetic response, reducing costs. This nano-displacement agent can solve the problems of poor efficiency, ineffective oil-water separation, high economic costs, and environmental impact associated with existing displacement agents.

A spin orbit torque (SOT) magnetic tunnel junction (MTJ) device includes a substrate, a seed layer over the substrate, and a bismuth antimony (BiSb) layer having a (0120) orientation on the seed layer. The seed layer includes a silicide layer and a surface control layer. The silicide layer includes a material of NiSi, NiFeSi, NiFeTaSi, NiCuSi, CoSi, CoFeSi, CoFeTaSi, CoCuSi, or a combination thereof. The surface control layer includes a material of NiFe, NiFeTa, NiTa, NiW, NiFeW, NiCu, NiCuM, NiFeCu, CoTa, CoFeTa, NiCoTa, Co, CoM, CoNiM, CoNi, NiSi, CoSi, NiCoSi, Cu, CuAgM, CuM, or a combination thereof, where M is Fe, Cu, Co, Ta, Ag, Ni, Mn, Cr, V, Ti, or Si.

The application provides a method for preparing a magnetic heterostructure material of magnetite-graphene and application of the magnetic heterostructure material in a directional heat-conducting composite material, and belongs to the technical field of composite materials. The method comprises the following steps: (1) slowly adding a sodium hydroxide solution into a ferric chloride solution under water bath condition to prepare a ferric hydroxide gel, and sequentially performing drying and aging, centrifugation, cleaning and freeze drying on the gel to obtain a ferrous oxide nanocrystal; (2) adding the ferrous oxide nanocrystal, graphene and dopamine hydrochloride into a Tris buffer solution and fully stirring, and performing multiple centrifugation, cleaning and freeze drying to obtain ferrous oxide-dopamine-graphene; and (3) performing calcination reduction on the ferrous oxide-dopamine-graphene to obtain the magnetic heterostructure material of magnetite-graphene. The magnetic heterostructure material prepared by the method can be applied to the preparation of the directional heat-conducting composite material as a heat-conducting filler, and has the advantages of high operability, low cost and the like.

The present invention relates to the technical field of metal soft magnetic powder preparation, and relates to an apparatus and method for preparing core-shell structured submicron powder by heat-insulated plasma arc-spray coating composite. The apparatus includes a heat-insulated plasma arc system, a spray coating system, and a circulation system connected in sequence. The apparatus of the present invention combines the two processes of preparing submicron powder and spray coating into one. By controlling the size and temperature of the heating zone, the collision and further growth of molten nanoclusters are promoted to prepare submicron metal soft magnetic particles. The submicron powder is kept in a dispersed suspension state by the circulating air flow combined with the stirring air flow to avoid particle agglomeration, and the processes of coating, hydrolysis, and drying are completed instantaneously to obtain spherical submicron metal soft magnetic particles coated with SiO2.

The present invention provides a nickel nanowire that does not break readily under stress. The present invention relates to a nickel nanowire having a face-centered cubic lattice structure and a crystallite size of 10 nm or less in the (111) lattice plane orientation.

The invention relates to high-frequency ultralow-loss iron-nickel alloy powder and a preparation method thereof.The powder comprises a powder core composed of iron-nickel alloy, the core comprises, by weight, 75.5%-77.5% of nickel, 4.5%-6.5% of molybdenum, 2%-3% of lanthanum and titanium, the mass ratio of lanthanum to titanium is 2: 1, and the balance is iron and inevitable impurities; the surface of the powder core is coated with an insulating metal oxide layer with the average thickness of 3 nm to 10 nm. The soft magnetic material prepared from the high-frequency ultralow-loss iron-nickel alloy powder has excellent high-frequency magnetic conductivity and low power loss, the high-frequency magnetic conductivity'under 50 MHz is 38-49, the power loss under 100 KHz / 100 mT is 260-281 mW / cm < 3 >, and high magnetic conductivity and power loss are still achieved under the high-frequency condition.

The invention relates to the technical field of magnetic particle imaging, in particular to a core-shell nanoprobe and a preparation method and application thereof.The core-shell nanoprobe comprises a magnetic core and a nanoshell which is located outside the magnetic core and has a magnetic shielding response function, and the structure of the nanoshell collapses under the tumor microenvironment condition; the saturation magnetization of the magnetic core is greater than or equal to 50 emu / g, and the coercive force is less than or equal to 5 Oe; the saturation magnetization of the nano shell is less than 50 emu / g, and the coercive force is more than 5 Oe. According to the core-shell nanoprobe, through a unique magnetic core-shell structure design and tumor microenvironment response characteristics, a magnetic shielding layer is formed by using a low-signal nano shell with a response magnetic shielding function, and background signal interference is inhibited. In a tumor microenvironment, the shell structure of the core-shell nanoprobe collapses, the magnetic core is exposed, and a high magnetic signal is released and generated, so that the imaging signal-to-noise ratio is remarkably improved. According to the invention, the bottleneck that the traditional MPI probe is lighted in the whole course can be broken through, the tumor specificity is lighted and positioned, and the problems that the external background of the tumor is high, the contrast ratio is poor, and tiny focuses are difficult to detect are solved.

The invention discloses an MMP-9-targeted MRI (Magnetic Resonance Imaging) nanoprobe and a preparation method and application thereof, the MMP-9-targeted MRI nanoprobe is represented by Gd-ACC-MAP and comprises amorphous calcium carbonate and an aptamer covalently connected to the surface of the amorphous calcium carbonate, the calcium carbonate is doped with gadolinium, and the aptamer has a nucleotide sequence as shown in SEQ ID NO: 1. The MRI nanoprobe can be used for early diagnosis of aneurysm and evaluation of rupture risk of the aneurysm.

In a first aspect, the present invention is directed to a magnetic particle having a saturation magnetization ≥ 15 Am2 / kg and having at least one azide group –N=N'-N- bonded to a polymer matrix of the magnetic particle. A second aspect of the invention relates to a process for preparing a magnetic particle, which comprises at least one magnetic core (M), a polymer matrix (P) comprising a crosslinked polymer at least partially surrounding the magnetic core (M), the polymer matrix (P) comprising on its surface at least a functional group reactive towards amine groups and / or hydroxyl groups. In a third aspect, the invention is directed to the magnetic particle obtained or obtainable from the process of the second aspect. A fourth aspect is related to a process for preparing a magnetic particle having a saturation magnetization ≥ 15 Am2 / kg of the first aspect, and a fifth aspect relates to the magnetic particle obtained or obtainable from the process of the fourth aspect. A sixth aspect is directed to the use of the magnetic particle having a saturation magnetization ≥ 15 Am2 / kg of the first aspect or of the fourth aspect for qualitative and / or quantitative determination of at least one analyte in a fluid or in a gas, and a seventh aspect relates to a method for determining at least one analyte in a fluid using said magnetic particle having a saturation magnetization ≥ 15 Am2 / kg.

An anisotropic electroconductive film and an electroconductive connector that make it possible to achieve lower resistance than the prior art, improved highfrequency characteristics and higher resolution, improved contact stability due to reduced contact pressure, increased electrical current capacity, and improved durability are provided. An anisotropic electroconductive film 110 includes an electrically insulative thin film 112 made of an elastic polymer material, and particles 200 made of a substance exhibiting topological antiferromagnetic properties, which are dispersed in the electrically insulative thin film 112 and which are given magnetic anisotropy so that an easy direction of magnetization is in a thickness direction of the electrically insulative thin film 112. The particles 200 form conduction portions 114 which are arranged at intervals in an in-plane direction of the electrically insulative thin film 100 for enabling electrical conduction along the thickness direction thereof. Each conduction portion 114 is formed by the single particle 200 (or the particles 200 aligned in the thickness direction). Each particle 200 has a south pole region 604 and a north pole region 602 formed respectively at two ends thereof along the easy direction of magnetization, and the south pole region and the north pole region are subject to concentration of magnetic flux of virtual magnetic fields.

The invention belongs to a nano-particle preparation method, and provides a ferromanganese-containing base magnetic nano-particle and a preparation method thereof in order to solve the technical problems that the clinical transformation of the magnetic nano-particle in tumor immunotherapy is limited and the magnetic nano-particle cannot be practically applied. The preparation method comprises the following steps: preparing dopamine hydrochloride-polyacrylic acid-polyethylene glycol into a basic magnetic nano-material, modifying the basic magnetic nano-material to obtain a modified material dopamine hydrochloride-polyacrylic acid-polyethylene glycol in order to enable the basic magnetic nano-material to have good biocompatibility, reacting the basic magnetic nano-material with the modified material in a deionized water system, and carrying out ultrasonic treatment, stirring and centrifugal cleaning treatment to obtain the water-soluble magnetic nano-material. And finally, the prepared magnetic nano-material is subjected to functionalization treatment, the ferromanganese-containing base magnetic nano-particles with good biocompatibility are obtained, and a new strategy is provided for multifunctional synergistic treatment of gastric cancer.