1556results about How to "Good reproducibility" patented technology

The invention discloses a method for preparing a single-layer tungsten diselenide nanoband based on a space confinement strategy. By changing the flow and the growth time of hydrogen, effective control on the width and the thickness of a nanoband can be realized. The method comprises the following steps: uniformly spraying tungsten trioxide powder to one substrate, then covering the substrate by the other substrate, and forming micro reaction space which is of a 'sandwich'-like structure. Growth of a tungsten diselenide nanoband is carried out by utilizing a constant-pressure chemical vapor deposition method; physicochemical characteristics of a one-dimensional transition metal chalcogenide strongly depend on suspension key types on the edge of the one-dimensional transition metal chalcogenide, metallic properties are displayed by an ultranarrow band, and conversion from the metallic properties to semiconductor properties can be displayed from the edge to the center of a wider band; the tungsten diselenide nanoband is widely applied to micro-nano photoelectric devices due to the special property; industrial production of the tungsten diselenide nanoband can be realized through an experimental method of the invention.

The invention discloses a method for analyzing mineral trace elements by utilizing a micro-Raman spectrum, which comprises the following steps of: fixing a mineral sample on a rotary sample table of a micro-Raman spectrometer, selecting an area to be detected by combining a micro-imaging technology, collecting a Raman background signal under the pre-illumination of low-power laser, and analyzing the trace elements in the area to be detected according to the Raman background signal. The laser focal length, the spot size and the incident angle are adjusted accordingly, the laser is focused on a target area, under the calibrated laser condition, through a multi-angle excitation micro-area, after an algorithm is applied to optimize signals, reduce impurity interference and integrate multi-angle Raman signals, the characteristic spectrum information of the microelements can be extracted, and the microelements can be accurately detected. High-resolution analysis of sample components is realized, and a three-dimensional distribution model of microelements in a microcell is constructed in combination with microscopic imaging data. The method has the characteristics of non-destructiveness, high resolution and rapid detection, and is suitable for mineral component analysis in the fields of geology, material science and the like.

The invention discloses a control method of a mechanical arm, the mechanical arm and a computer readable storage medium. The method comprises the steps of receiving a task instruction and an environment image; wherein the environment image has depth information; inputting the task instruction and the environment image into a large language model, so that the large language model outputs natural language instructions corresponding to the sub-tasks in sequence; wherein the large language model does not have code generation capability; wherein each subtask is predicted when the execution of the previous subtask is completed; and the natural language instructions are sequentially input into the mechanical arm control model according to the sequence, so that the mechanical arm control model controls the mechanical arm to execute corresponding actions based on the natural language instructions until all the subtasks are completed. By means of the mode, the problem that in the related technology, understanding of action semantics is insufficient can be solved.

The invention discloses a construction method and application of an electrochemical luminescence (ECL) antifouling sensor based on zwitter-ion hydrogel, and belongs to the technical fields of photoelectric sensing analysis, interface antifouling and environmental science. According to the invention, the hydrogel based on sulfobetaine methacrylate zwitterions and bovine serum albumin is used as the antifouling coating, so that the adsorption of biological proteins and bacteria is effectively hindered, and the service life of the sensor is prolonged. Meanwhile, the interior label Au (at) luminol is packaged in the antifouling hydrogel, so that the integration of interface antifouling and ratio detection is realized, the detection accuracy is improved, and the construction process of the ECL sensor is simplified. The constructed ECL anti-pollution sensor has high sensitivity to chloramphenicol detection, the detection limit is 0.39 pM, and the ECL anti-pollution sensor is suitable for trace detection of antibiotics in seawater.

The invention relates to the field of establishment of fingerprints of traditional Chinese medicinal materials, in particular to an establishment method and application of a salvia miltiorrhiza polysaccharide HPLC (High Performance Liquid Chromatography) fingerprint. The establishment method comprises the following steps: preparation of a test solution: taking a salvia miltiorrhiza polysaccharide hydrolysis solution, carrying out derivatization in a reaction bottle, and passing through a 0.1-0.3 [mu] m microporous filter membrane; preparing a reference substance solution, namely weighing mannose, ribose, rhamnose, glucuronic acid, galacturonic acid, glucose, galactose and arabinose reference substances, and preparing into a mixed reference substance solution; performing HPLC (high performance liquid chromatography) determination; and establishing the salvia miltiorrhiza polysaccharide HPLC fingerprint spectrum. According to the method, the difference of monosaccharide composition and content in salvia miltiorrhiza medicinal materials from different producing areas and the spectrum-effect relationship between antioxidant activity and anticoagulant activity are clarified, and a certain reference basis is provided for quality control and evaluation of the salvia miltiorrhiza medicinal materials from the aspect of polysaccharide.

The invention provides a supported IrOx catalyst as well as a preparation method and application thereof. The supported IrOx catalyst comprises an oxide carrier and an active component supported on the carrier, the active component comprises an Ir elementary substance and amorphous IrOx coated on the surface of the Ir elementary substance; and the crystal structure of the IrOx is long-range disordered and short-range ordered. The preparation method of the supported IrOx catalyst is convenient to implement, high in reproducibility and beneficial to industrial preparation and production, gram-level batch preparation can be achieved under the laboratory condition, and possibility is provided for large-scale preparation of the low-cost, high-activity and high-stability proton exchange membrane water electrolysis hydrogen production anode catalyst.

The invention relates to a method for improving quality control of cefditoren pivoxil granules, which comprises the following steps: injecting a cefditoren pivoxil granule sample solution into a high performance liquid chromatograph for analysis so as to detect impurities in the cefditoren pivoxil granules, in the high performance liquid chromatography, a mixed solution of an ammonium formate solution, acetonitrile and methanol (43-47): (23-27): (23-27) is used as a mobile phase A, a mixed solution of an ammonium formate solution, acetonitrile and methanol (43-47): (53-57): (53-57) is used as a mobile phase B, gradient elution is adopted, and a cefditoren pivoxil particle sample solution is prepared by using the mobile phase A as a diluent. According to the method disclosed by the invention, the forward delay phenomenon of an open-loop impurity peak of the cefditoren pivoxil in the cefditoren pivoxil granules and the separation degree of an unknown impurity peak are improved, the reproducibility is good, and the accuracy is high, so that the quality control level of the cefditoren pivoxil granules is improved.

The invention discloses aggregation-induced emission microspheres with colorimetric-fluorescence double signals as well as a preparation method and application of the aggregation-induced emission microspheres. The aggregation-induced emission microsphere comprises a carboxyl polystyrene microsphere and an aggregation-induced emission dye embedded in the carboxyl polystyrene microsphere, the aggregation-induced emission microsphere has colorimetric-fluorescence double signals, is red under natural light, has strong absorption at 600nm, shows high luminous efficiency at 725nm, not only effectively avoids the interference of biological autofluorescence and reduces background interference, but also has good light stability and photobleaching resistance, and can be used for preparing the aggregation-induced emission microsphere. And due to the high molar extinction coefficient, the colorimetric and fluorescent double-signal output capability is realized at the same time. In addition, the aggregation-induced emission microspheres are high in reproducibility in the preparation process, have the potential of large-scale synthesis and meet the requirements of industrial batch production.

The invention belongs to the technical field of medicine detection, and particularly relates to a high-sensitivity liquid chromatography method for detecting mutagenic impurities in atomoxetine hydrochloride key starting material 3-chlorobenzene propanol, the method adopts an HPLC (High Performance Liquid Chromatography) analysis method, a chromatographic column adopts octadecylsilane chemically bonded silica as a filler, and the composition of a mobile phase A is a buffer solution; the mobile phase B is methanol or acetonitrile; carrying out gradient elution on the mobile phase; the flow velocity is 0.4 to 0.8 ml / min; the detection wavelength is 230 to 250 nm; by adopting an HPLC analysis method, the content of mutagenic impurities in the key starting material 3-chlorobenzene propanol of atomoxetine hydrochloride can be effectively separated and measured, and the method is high in sensitivity, strong in specificity and good in accuracy and repeatability, and has extremely important significance on quality control of the key starting material 3-chlorobenzene propanol of atomoxetine hydrochloride.

The invention discloses a construction method and application of a zwitter-ion antifouling and dual-signal-ratio electrochemical biosensor, and belongs to the technical field of biochemical sensing analysis and life science. According to the invention, 3-aminopropyl dimethylamine oxide (APDMAO) zwitterions are prepared to be used as an antifouling interface. Specific positive and negative charges (N < + >-O-) of APDMAO promote hydrogen bond combination with water molecules, and a firm hydration barrier is formed. Meanwhile, the development of APDMAO overcomes the defect that zwitterions are difficult to synthesize and modify, and the application of APDMAO in biosensing analysis is expanded. A methylene blue (MB) internal standard modified alpha fetoprotein (AFP) aptamer is coupled with APDMAO under a controllable potential, so that the detection precision of the sensor is improved. The constructed ratio type electrochemical antifouling biosensor realizes sensitive and accurate detection of AFP, and the detection limit is as low as 3.41 fg / mL.

The invention discloses a sewage heavy metal ion detection device, which belongs to the technical field of sewage detection, and comprises a sensor module and a microfluidic module, the sensor module comprises a Loff wave surface acoustic wave device, the Loff wave surface acoustic wave device comprises a resonance area and two Loff wave interdigital transducers, the resonance area is located between the two Loff wave interdigital transducers, and the resonance area is covered with a heavy metal ion adsorption film; the micro-fluidic module comprises a micro-channel system and a Rayleigh wave surface acoustic wave device, the micro-channel system comprises a dropwise adding tank, a micro-channel and a waste liquid tank which are communicated in sequence, the micro-channel is provided with an experimental area overlapped with the resonance area, and the Rayleigh wave surface acoustic wave device is used for driving sewage to move from the dropwise adding tank to the waste liquid tank. By combining a microfluidic technology and a surface acoustic wave technology, heavy metal ions, especially lead ions, in sewage can be rapidly, accurately and conveniently monitored.

The invention provides a micro-area variable-angle grazing incidence wide-angle scattering test method based on a single-crystal X-ray diffractometer, which comprises the following steps: preparing a sample from a test material deposited on a substrate, and placing the sample on an improved sample rack which is provided with a specific structure and a driver for controlling an incident angle and the like; selecting an X-ray light source, aligning the X-ray light source with the sample, and switching and matching a copper target and a molybdenum target; z-scan scanning and tilting scanning along a light path direction and a direction vertical to the light path are carried out, and related parameters are set; the scattered X-rays are collected through a two-dimensional surface detector; and finally obtaining a correlation graph through software integration. Specific requirements for the table size, scanning parameters and the like of the improved sample holder are met, a height reference position, an adjusting structure and the like are further arranged, and a connecting part is installed on an equipment sample table through screw joint. The problems of inaccurate incident angle and height control and the like in the prior art are solved, and the test accuracy and reliability are improved.

The invention provides a position correction method for rapid acquisition of a transmission electron microscope, which is used for acquiring images of the transmission electron microscope at multiple angles. Through mathematical fitting of the relation between the image position (x, y) and the sample rod tilting angle (angle) and the relation between the focusing value (focus) and the sample rod tilting angle (angle), the position error and the focusing change caused by tilting are effectively corrected, so that the alignment precision and the imaging quality of the image are improved; according to the method, correction efficiency and automation can be greatly improved by substituting accurate numerical values into a fitting function, and the method has remarkable technical progress and application value in the aspect of improving multi-angle imaging and three-dimensional reconstruction of the transmission electron microscope.

The invention belongs to the technical field of fiber size measurement, and particularly relates to a method for measuring the length of fibers in a fiber reinforced thermoplastic composite material. Mixing and diluting the fiber reinforced thermoplastic composite material and thermoplastic resin to obtain a diluted material, pressing the diluted material to obtain a test sample strip, cutting the test sample strip into a sample wafer, and measuring the length of the fiber in the sample wafer under an optical microscope; wherein the fiber reinforced thermoplastic composite material is prepared from matrix resin and reinforced fibers, and the matrix resin is the same as thermoplastic resin. According to the invention, the problems of poor measurement result accuracy and reproducibility and low measurement efficiency of the existing fiber length measurement method for the fiber reinforced thermoplastic composite material are solved.

The utility model provides an aircraft control assembly rapid troubleshooting test device, comprising a test host computer and a test circuit board, the test host computer sends a test control instruction to the test circuit board, and the test circuit board outputs a discrete signal for the test of a to-be-tested device to the to-be-tested device after receiving the test control instruction. And after the to-be-tested device receives the test discrete signal, test feedback information is transmitted to the test circuit board, and the test circuit board sends the test feedback information to the test upper computer, so that the test upper computer processes the test feedback information to judge whether the function of the to-be-tested device is normal or not. Compared with a traditional test bench test method, the method has the advantages that functions which cannot be realized by a traditional test bench can be realized by using existing software and hardware, the time for completing the test of a single aircraft control assembly is shorter, the test efficiency is higher, a more efficient and effective test program is realized, and the overall quality and reliability of the aircraft control assembly are improved.

The invention discloses a preparation method of recombinant collagen nano-composite hydrogel for repairing wounds infected by multiple drug-resistant bacteria, which comprises the following steps: binding copper porphyrin pi-pi on titanium carbide nanosheets to form MXene coated CuTCPP nanoparticles, and carrying out amidation reaction on 3-aminophenylboronic acid and recombinant collagen to obtain the recombinant collagen nano-composite hydrogel for repairing wounds infected by multiple drug-resistant bacteria. MXene coated CuTCPP is doped into a modified recombinant collagen system and mixed with a polyvinyl alcohol solution, and the recombinant collagen nano-composite hydrogel is prepared. The self-healing property endowed by the dynamic cross-linking characteristic of the phenylboronic acid ester bond in the composite hydrogel disclosed by the invention can be highly adapted to irregular wounds; the nano particles with the heterojunction structure can be combined with photothermal therapy and photodynamic therapy to efficiently sterilize wounds; the hydrogel has the antibacterial property and the property of promoting wound healing, and can comprehensively and efficiently treat wounds infected by multiple drug-resistant bacteria.

The invention discloses a bifidobacterium pseudocatenum freeze-drying protective additive and application, and the bifidobacterium pseudocatenum freeze-drying protective additive is prepared from the following raw materials in percentage by weight: 2%-10% of dried skim milk, 5%-20% of cane sugar, 1%-6% of fructo-oligosaccharide, 0.5%-3% of sodium glutamate, 0.5%-2% of sodium ascorbate, 3%-15% of betaine and the balance of distilled water. The freeze-drying protective agent is simple in component composition, the survival rate of the bifidobacterium pseudocatenum in the freeze-drying process can be increased by using the freeze-drying protective agent, the freeze-drying survival rate of the bifidobacterium pseudocatenum reaches 76.3% or above, the stability of the freeze-drying preparation is guaranteed, and meanwhile the obtained freeze-drying preparation has the advantages of being easy to operate and the like, and has good application prospects. The preparation method of the freeze-dried preparation is simple and feasible, mild in condition, good in reproducibility, strong in controllability, suitable for large-scale production, and more convenient for clinical use and storage.

The invention provides a method for simultaneously detecting perfluorinated compounds in mouse tissues and organs, and belongs to the technical field of analysis and detection. The method provided by the invention comprises the following steps: mixing a mouse visceral organ tissue sample, an alkaline buffer solution and an internal standard solution, and homogenizing to obtain homogenate; mixing the homogenate with tetrabutylammonium hydrogen sulfate and methyl tert-butyl ether, and carrying out liquid-liquid extraction to obtain extract liquor; and sequentially drying and redissolving the extract liquor, and carrying out ultra-high performance liquid chromatography-tandem mass spectrometry analysis to obtain a result of the perfluorinated compound in the mouse tissue visceral organs. The result of the embodiment shows that the adding standard recovery rate of 14 target objects in the method provided by the invention is 64.9%-120.3%, the RSD of 6 repeated tests is 1.0%-14.0%, the matrix effect of the target objects is 83.7%-134.0%, and the matrix effect is relatively low; and the detection result has excellent accuracy and reproducibility.

The invention discloses a magnetic resonance imaging ion concentration real-time detection method for an aqueous ion battery. The method comprises the following steps: SO, assembling the aqueous ion battery; the method comprises the following steps: S1, putting an aqueous ion battery into a detection area of a magnetic resonance imager, and connecting an electrochemical workstation; s2, determining an area where an electrode-electrolyte interface is located through a magnetic resonance imager; and S3, electrifying, and acquiring two-dimensional image data of a collector-electrolyte interface at equal intervals to obtain a characterization map of the ion concentration of the electrolyte. The method is suitable for the magnetic resonance imager to detect the battery in an in-situ experiment, the ion concentration information of the aqueous ion battery-electrode interface can be obtained, so that deposition and stripping of electrode interface metal are analyzed, the control sensitivity is high, the detection result is stable and reliable, and the method has the possibility of wide popularization.

The invention discloses a construction method and application of a ratio-dependent electrochemical luminescence (ECL) biosensor based on an antifouling red cell membrane, and belongs to the technical fields of photoelectric analysis, biosensing and interface antifouling. In the invention, the erythrocyte membrane with super-hydrophilicity and low membrane protein content is used as an efficient antifouling interface, and the good biocompatibility of the erythrocyte membrane avoids the influence of a chemical antifouling coating on the biological activity of the ECL sensor. Meanwhile, the electropolymerized polyaniline nanowire is embedded into the antifouling erythrocyte membrane, so that the chemical stability and the conductivity of the antifouling erythrocyte membrane are enhanced, and the application of the antifouling erythrocyte membrane in ECL analysis is expanded. C3N4 is introduced as an interior label for eliminating background signals and external interference, so that the detection precision of the biosensor is improved. On the basis, the constructed ECL antifouling biosensor realizes ultra-sensitive detection of human breast cancer cells MCF-7 in human serum, and the detection limit is as low as 3 cells / mL.

The invention discloses an automatic extraction method for semiconductor device model parameters, and the method comprises the steps: obtaining a multi-target response through the key parameters of a semiconductor device model, and constructing and training an agent model to predict a target response mean value and uncertainty parameters; constructing a multi-objective optimization collaborative circulation framework assisted by an agent model; generating a candidate parameter population in key parameters according to a position updating mechanism of a multi-objective optimization algorithm, predicting candidate parameters by using a trained proxy model, selecting the candidate parameters according to a prediction result to carry out real simulation evaluation, adding an obtained real sample into a non-dominated file, and updating the file based on a non-dominated relationship. Adding a training set dynamic updating agent model into the real sample, generating a potential search trajectory, selecting a representative representative Pareto approximate solution from the potential search trajectory, and updating the position of the population and the direction of the next-generation search trajectory according to the representative solution selected from the file; and terminating the circulation, outputting the solution set in the file, and checking.

The invention discloses a gene RBOHB and application of the gene RBOHB in regulating and controlling waterlogging stress to induce cucumber adventitious root formation, a novel gene RBOHB for inducing cucumber adventitious root formation is identified, the adventitious root formation capability of an edited mutant of the gene RBOHB is weakened, the extension of the adventitious root is obviously inhibited, and the adventitious root formation capability of an overexpressed mutant is enhanced. The gene RBOHB disclosed by the invention is used for regulating and controlling the waterlogging tolerance of cucumbers, and has important application value in screening and improving waterlogging-tolerant germplasm resources of the cucumbers and breeding waterlogging-tolerant varieties of the cucumbers. The cucumber is subjected to transgenic genetic transformation through a gene editing technology and a gene overexpression technology, the cucumber waterlogging tolerance regulation gene RBOHB and application of the cucumber waterlogging tolerance regulation gene RBOHB in waterlogging tolerance cucumber varieties are provided, and the cucumber waterlogging tolerance regulation gene RBOHB has important application value in the field of breeding of resistant cucumbers.

The invention provides a photoelectrochemical biosensor based on a porous membrane as well as a preparation method and application of the photoelectrochemical biosensor, and belongs to the field of photoelectrochemical biosensors. The photoelectrochemical biosensor comprises an electrode, the electrode comprises ITO conductive glass and a composite film coated on the ITO conductive glass, the composite film is obtained by modifying a photosensitive material in a nano-pore channel of a porous film and then connecting a capture probe in the nano-pore channel, and the photoelectrochemical biosensor based on the porous film is obtained. The sensor has the following advantages: 1, other biomolecules can be detected by changing the type of the capture probe, and the sensor has excellent practical application value; 2, the ITO conductive glass is loaded with the porous membrane to replace a traditional metal electrode, so that the detection is accurate, the detection time is short, the cost is low, and the reproducibility and the stability are good;

The present invention provides a kind of spherical gold powder and preparation method thereof, relate to the technical field of precious metal powder preparation, the preparation method uses aqua regia to prepare chloroauric acid solution, and uses concentrated hydrochloric acid to adjust pH to 1.5-2, then adds ammonia water to adjust pH to 7-9, stirs 20-60s, then adds concentrated hydrochloric acid to adjust pH to 1.2-2 again, obtains mixed solution B;Then, the first dispersant solution is poured into the aforementioned mixed solution B, after stirring evenly, the mixed solution A of the second dispersant and the reducing agent is quickly added, after stirring reaction, sedimentation, post-treatment, obtains spherical gold powder. Wherein, spherical gold powder of different sizes with a particle size within the range of 0.3-4 μm can be prepared by adjusting pH twice, and adding two different dispersants in a specific order of addition can make the prepared spherical gold powder uniform in particle size, good in dispersibility, regular in shape and smooth in surface. The preparation method reacts rapidly, the process is short and stable, and it has been stably expanded to 500g, which can realize large-scale industrial production.

The invention belongs to the technical field of ammonia synthesis and electro-catalysis, and particularly relates to a preparation method and application of high-entropy alloy aerogel for electro-catalysis. The preparation method comprises the following steps: mixing an inorganic metal salt in a solvent to obtain a precursor solution, quickly adding a reducing agent, standing, and washing and drying the obtained product to obtain the high-entropy alloy aerogel catalyst, the inorganic salt is selected from five or more of copper salt, cobalt salt, iron salt, nickel salt, palladium salt, gold salt, ruthenium salt, platinum salt and silver salt. The three-dimensional continuous porous reticular high-entropy alloy aerogel is obtained through one-step reduction of the inorganic metal salt and standing assembly, the high-entropy alloy aerogel prepared through the method is high in reduction assembly speed, phase separation of multi-component alloy can be effectively inhibited, an amorphous alloy structure is obtained, and therefore when the high-entropy alloy aerogel is applied to ammonia production through electro-catalysis nitrate reduction, the high-entropy alloy aerogel can be used for preparing the high-entropy alloy aerogel. And excellent electrochemical activity and stability can be presented in an ultra-low overpotential range of-0.2 to + 0.2 V vs.RHE.

The invention relates to the technical field of biology, in particular to a benzene-induced blood abnormality marker, an evaluation model and a construction method and application of the benzene-induced blood abnormality marker and the evaluation model, and provides the following scheme that the method comprises the steps that S1, principal component analysis is conducted on benzene damage expression profile data sets, then preliminary screening conditions are set, and differential expression genes between the benzene damage expression profile data sets are screened out; s2, carrying out GO, KEGG and GSEA enrichment analysis on the differentially expressed gene to obtain an analysis result; s3, different machine learning algorithms are used for screening characteristic genes from analysis results, intersection is taken, key genes are obtained, then verification analysis is conducted on the key genes, and benzene damage marker genes are obtained; and S4, training and testing a plurality of learning models by using the benzene injury marker gene, and selecting a proper learning model as a benzene-induced blood abnormality evaluation model according to a test result of the learning model. According to the invention, a theoretical basis can be provided for early intervention of benzene toxicity, and a more comprehensive and sensitive model can be provided for risk assessment.

The invention discloses a laser vibration meter series reciprocating type optical frequency modulation calibration method and device, and belongs to the field of photoelectric measurement. The calibration device is mainly composed of a calibrated laser vibration meter, a first acousto-optic modulator, a second acousto-optic modulator, a lens, a first sinusoidal signal source, a second sinusoidal signal source, an FM signal source and a plane mirror. Aiming at a laser signal emitted by the laser vibration meter, the reversibility characteristic of a light path is utilized, a straight-line-shaped light path structure is used, a secondary light frequency modulation mode of the same group of optical devices is combined with secondary light frequency translation to realize output frequency translation and modulation control of the laser vibration meter, and a laser Doppler effect caused by different vibration waveform magnitude values is simulated. And the modulated laser is completely returned to the calibrated laser vibration meter in the original path, so that the change waveform of the vibration velocity value is replaced by the change waveform of the frequency value, and the calibration of the laser vibration meter is realized. The device has the advantages of portability, wide frequency range, wide amplitude range calibration, high precision and good stability.

The invention belongs to the technical field of optical fiber sensing, and discloses an optical fiber seawater salinity sensor with a temperature self-compensation function, a preparation method and a test system. The sensor is based on a single-mode fiber-hollow fiber-single-mode fiber (SHS) structure partially filled with a temperature-sensitive material, and simultaneously excites Fabry-Perot interference and an anti-resonance effect. The femtosecond laser micromachining technology is adopted for optical fiber microdefect etching, temperature-sensitive material filling and seawater flowing into the SHS structure through the microdefects are facilitated, the problem that the anti-resonance phenomenon cannot be excited under the liquid immersion condition is solved, and high-sensitivity salinity measurement is achieved. The temperature crosstalk in the salinity measurement process is compensated based on the temperature-sensitive material filled Fabry-Perot interferometer, and the measurement error is reduced. The optical fiber sensor is compact in structure, has good stability, repeatability and reproducibility, has wide application potential in the field of microfluidics, and provides technical support for application of optical sensing in the ocean.

The invention discloses high-oxygen-permeability silicone hydrogel contact lenses, which are prepared from the following raw material components in percentage by mass: 30 to 40 percent of macromolecular siloxane I, 5 to 10 percent of macromolecular siloxane II, 10 to 20 percent of micromolecular siloxane, 20 to 30 percent of hydrophilic monomers, 2 to 5 percent of humectants, 0.5 to 1.5 percent of cross-linking agents, 0.5 to 1 percent of initiators and 2 to 5 percent of functional monomers. The macromolecular siloxane I adopted by the silicone hydrogel contact lens is narrow in molecular weight distribution and good in reaction repeatability, a quaternary ammonium salt functional group is introduced into the macromolecular siloxane I, uniformity of the macromolecular siloxane in a PP mold is facilitated, and the lens has a better hydrophilic surface; meanwhile, preparation process equipment of the macromolecular siloxane I is simple, raw materials are cheap and easy to obtain, and operation is convenient; the obtained lens is high in oxygen permeation coefficient, and the lens with good surface hydrophilicity and good wetness can be obtained without surface treatment.

The invention relates to the technical field of oral solid preparations, in particular to a high-bioavailability coenzyme Q10 tablet and a preparation method thereof. The coenzyme Q10 tablet comprises an active component coenzyme Q10, a filler, an adhesive, a disintegrating agent, a lubricant and a high polymer material, compared with the prior art, hydroxyethyl methylcellulose and hydroxypropyl methylcellulose succinate are mixed according to a certain mass ratio to serve as a high polymer carrier material, the prepared coenzyme Q10 tablet can be rapidly dissolved out in vitro, and the coenzyme Q10 tablet has the advantages that the preparation process is simple, and the cost is low. Moreover, the stability of the medicine can be improved, the medicine can be rapidly absorbed in vivo after being orally taken, the oral bioavailability of the coenzyme Q10 is greatly improved, and a preparation process of the preparation is simple to operate, good in reproducibility and suitable for industrial production.