32828results about How to "Reduce the amount required" patented technology

A coated surgical fastener is provided for an easy visualization within tissue. The coated surgical fastener includes a core and a relatively non-reflective coating applied about the core. There is also disclosed an illuminated staple cartridge for use with a surgical stapling device having a light source. The illuminated staple cartridge includes a transparent insert and a relatively nontransparent U-shaped outer channel at least partially surrounding the transparent insert. Windows formed in sides of the U-shaped outer channel allow defined amounts of light to project from the sides of the illuminated staple cartridge.

A near-to-eye display system for forming an image as an illuminated region on a retina of at least one eye of a user is disclosed. The system includes a source of modulated light, a proximal optic positionable adjacent an eye of the user to receive the modulated light. The proximal optic has a plurality of groups of optically redirecting regions. The optically redirecting regions are configured to direct a plurality of beams of the modulated light into a pupil of the eye to form a contiguous illuminated portion of the retina of the eye. A first group of the optically redirecting regions is configured to receive modulated light from the source and redirect beams of the modulated light into the pupil of the eye for illumination of a first portion of the retina. A second group of the optically redirecting regions is configured to receive modulated light from the source and redirect beams of the modulated light into the pupil of the eye for illumination of a second portion of the retina.

Surgical devices, systems and methods for treating tissue are provided. An exemplary surgical device comprises a tip portion including first and second jaws each having a tissue grasping surface, at least one of the jaws being movable toward the other jaw. The tissue grasping surface of each jaw has includes an electrically insulative surface. The device also includes first and second electrodes connectable to different terminals of an RF generator to generate electrical current flow therebetween, with each of the electrodes having an electrode surface. One of the electrode surfaces is located on one of the jaws separated from one edge of the tissue grasping surface, and the other of the electrode surfaces is located on one or the other of the jaws separated from the other edge of the tissue grasping surface. The device also includes at least one fluid passage being connectable to a fluid source.

The present invention features PD-1 binding proteins, a subset of which inhibits binding of PD-L1 to the PD-1 receptor. These binding proteins can be employed to modulate the immune system through the manipulation of the PD-1 signaling pathway, enhancing host immunity to treat infections and cancer.

Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

Exploiting the substantive reciprocity of internode channel responses through dynamic, adaptive modification of receive and transmit weights, enables locally enabled global optimization of a multipoint, wireless electromagnetic communications network of communication nodes. Each diversity-channel-capable node uses computationally efficient exploitation of pilot tone data and diversity-adaptive signal processing of the weightings and the signal to further convey optimization and channel information which promote local and thereby network-global efficiency. The preferred embodiment performs complex digital signal manipulation that includes a linear combining and linear distribution of the transmit and receive weights, the generation of piloting signals containing origination and destination node information, as well as interference-avoiding pseudorandom delay timing, and both symbol and multitione encoding, to gain the benefit of substantive orthogonality at the physical level without requiring actual substantive orthogonality at the physical level.

Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

A surgical stapler that may have a head assembly, a stapling assembly, a shield, a base head, a handle assembly, and a shaft assembly. A head assembly may have an anvil and anvil shaft, as well as a stapling assembly. A stapling assembly may have a trocar that can be removeably detachable with the anvil, a cannula extension, and a plurality of staples. A shield may be configured to retract from a first extended position where the shield generally covers the stapling assembly or the head assembly, to a second retracted position where the shield generally exposes the stapling assembly or the head assembly. The shield may be integral with the stapler, or provided after-market as an add-on. A surgical stapler may additionally or alternatively include an air or gas pump assembly that can be used to insufflate the rectum and intestinal tract during insertion and advancement of the stapler.

Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

A jaw movement mechanism for surgical tools has improved mechanical efficiency and other advantages. The jaw movement mechanism controls the orientation and position of a movable jaw relative to a fixed jaw through a range of movement of the movable jaw. The jaws maintain a parallel orientation throughout a portion of the range of movement of the movable jaw. The jaws maintain an angular relationship throughout a portion of the range of movement of the movable jaw.

A surgical stapler that may have a head assembly, a stapling assembly, a shield, a base head, a handle assembly, and a shaft assembly. A head assembly may have an anvil and anvil shaft, as well as a stapling assembly. A stapling assembly may have a trocar that can be removeably detachable with the anvil, a cannula extension, and a plurality of staples. A shield may be configured to retract from a first extended position where the shield generally covers the stapling assembly or the head assembly, to a second retracted position where the shield generally exposes the stapling assembly or the head assembly. The shield may be integral with the stapler, or provided after-market as an add-on. A surgical stapler may additionally or alternatively include an air or gas pump assembly that can be used to insufflate the rectum and intestinal tract during insertion and advancement of the stapler.

Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

A porous substrate or implant for implantation into a human or animal body constructed from a structural material and having one or more regions which when implanted are subjected to a relatively lower mechanical loading. The region(s) are constructed with lesser mechanical strength by having a lesser amount of structural material in said region(s) relative to other regions. This is achieved by controlling pore volume fraction in the regions. A spacer is adapted to define an open-cell pore network by taking a model of the required porous structure, and creating the spacer to represent the required porous structure using three-dimensional modelling. Material to form the substrate about the spacer in infiltrated the scaffold structure formed.

A coated surgical fastener is provided for an easy visualization within tissue. The coated surgical fastener includes a core and a relatively non-reflective coating applied about the core. There is also disclosed an illuminated staple cartridge for use with a surgical stapling device having a light source. The illuminated staple cartridge includes a transparent insert and a relatively nontransparent U-shaped outer channel at least partially surrounding the transparent insert. Windows formed in sides of the U-shaped outer channel allow defined amounts of light to project from the sides of the illuminated staple cartridge.

A forced discharge mechanism for a storage battery for forcibly establishing conduction between a pair of power transport paths that are respectively connected to a positive electrode terminal and a negative electrode terminal of the storage battery includes an electric resistor for establishing conduction between the power transport paths, and the electric resistor is movable due to a buoyant force of liquid that has entered.

Rich multimedia content is provided to a wireless device, particularly in response to a request for directory assistance generated by a client application. The multimedia content is provided as a multimedia message including bundled multimedia elements such as images, sound, text, and video files. The multimedia elements are compiled into a single multimedia presentation or deck that includes multiple screens that are automatically advanced for the convenience of the wireless device user. The user can interact with elements of the multimedia presentation, for example by placing orders, providing payment information, controlling playback, and forwarding or saving the deck to the wireless device. Multiple decks may be retrieved by a single request, and the decks are presented in an order determined by a bidding system or according to user preferences. Elements can be presented visually and / or audibly, and the user can interact using voice commands, manual entries, or stored entries.

An alignment system uses a self-referencing interferometer that produces two overlapping and relatively rotated images of an alignment markers. Detectors detect intensities in a pupil plane where Fourier transforms of the images are caused to interfere. The positional information is derived from the phase difference between diffraction orders of the two images which manifests as intensity variations in the interfered orders. Asymmetry can also be measured by measuring intensities at two positions either side of a diffraction order.

The present invention relates to compositions and methods for treating, characterizing, and diagnosing cancer. In particular, the present invention provides gene expression profiles associated with solid tumor stem cells, as well as novel stem cell cancer markers useful for the diagnosis, characterization, and treatment of solid tumor stem cells.

A color mapping process enhances a watermark by computing a change in colors that is less visible for a given watermark strength. The mapping process provides smooth transitions from one color region to another, and may be implemented efficiently with a 3D look up table. A user interface scheme enables the user to control encoding of the watermark in desired color regions.

In order to maintain the integrity of data stored in a flash memory that are susceptible to being disturbed by operations in adjacent regions of the memory, disturb events cause the data to be read, corrected and re-written before becoming so corrupted that valid data cannot be recovered. The sometimes conflicting needs to maintain data integrity and system performance are balanced by deferring execution of some of the corrective action when the memory system has other high priority operations to perform. In a memory system utilizing very large units of erase, the corrective process is executed in a manner that is consistent with efficiently rewriting an amount of data much less than the capacity of a unit of erase.

Video coding methods and apparatuses are provided that make use of various models and / or modes to significantly improve coding efficiency especially for high / complex motion sequences. The methods and apparatuses take advantage of the temporal and / or spatial correlations that may exist within portions of the frames, e.g., at the Macroblocks level, etc. The methods and apparatuses tend to significantly reduce the amount of data required for encoding motion information while retaining or even improving video image quality.

Current phacoemulsification handpieces require rigorous cleaning after each procedure because the aspiration and irrigation pathways for fluids are integral to the handpiece. According to the present invention, a removable horn extension and nosecone may be used with a phacoemulsification handpiece to allow for disposable fluid pathways exterior to the handpiece. This will reduce the cleaning time and effort, reduce cross-contamination, and increase the lifespan of the handpiece. Furthermore, the current invention allows different horn extensions to be used to excite different motions at the tip of the handpiece, depending on the preference of the surgeon.

A system, including software components, that efficiently and dynamically analyzes changes to data sources, including application programs, within an integration environment and simultaneously re-codes dynamic adapters between the data sources is disclosed. The system also monitors at least two of said data sources to detect similarities within the data structures of said data sources and generates new dynamic adapters to integrate said at least two of said data sources. The system also provides real time error validation of dynamic adapters as well as performance optimization of newly created dynamic adapters that have been generated under changing environmental conditions.

Exploiting the substantive reciprocity of internode channel responses through dynamic, adaptive modification of receive and transmit weights, enables locally enabled global optimization of a multipoint, wireless electromagnetic communications network of communication nodes. Each diversity-channel-capable node uses computationally efficient exploitation of pilot tone data and diversity-adaptive signal processing of the weightings and the signal to further convey optimization and channel information which promote local and thereby network-global efficiency. The preferred embodiment performs complex digital signal manipulation that includes a linear combining and linear distribution of the transmit and receive weights, the generation of piloting signals containing origination and destination node information, as well as interference-avoiding pseudorandom delay timing, and both symbol and multitone encoding, to gain the benefit of substantive orthogonality at the physical level without requiring actual substantive orthogonality at the physical level.