A method of producing a 
diode drive current in an oximeter includes sensing at least a part of a current passing through the 
diode and converting the sensed current to a sensed 
voltage, inputting the sensed 
voltage to a feedback 
amplifier for stabilizing the current passing through the 
diode, and eliminating an offset 
voltage across inputs of the feedback 
amplifier. A pulse oximeter includes a diode for emitting 
light flashes, a feedback 
amplifier having inputs, a 
feedback capacitor, and an output, the feedback amplifier stabilizing a current passing through the diode, a nulling amplifier having inputs, a nulling 
capacitor, and an output, the nulling amplifier charging and discharging the 
feedback capacitor until the inputs of the feedback amplifier are at a same voltage. The operation may include 
synchronizing an 
elimination of input offset voltages of the feedback and nulling amplifiers with on or off state of diode current.