65875 results about "Analytical chemistry" patented technology

Provided herein are methods for capturing a connected probe and / or a capture handle sequence to a capture domain of a capture probe.

The invention discloses a ppb-grade methane gas online detection method, equipment, a medium and a product, and relates to the field of data processing. The method comprises the following steps: acquiring an infrared absorption spectrum signal, and obtaining original spectrum data; performing multi-scale noise separation and baseline correction on the original spectral data to obtain de-noised effective spectral features, and extracting methane specific absorption peaks from the de-noised effective spectral features; comparing the methane specific absorption peak with the interference gas spectral line through a multi-spectral line weight matching algorithm to obtain methane characteristic intensity; carrying out self-adaptive calibration on the methane characteristic intensity according to the drift compensation model to obtain calibrated characteristic intensity; obtaining a ppb-level methane concentration value through a concentration inversion model; and inputting the sorted concentration time sequence data into an anomaly detection model to detect a methane leakage event. By designing signal processing and algorithm analysis, the dependence on equipment hardware performance is reduced, and the use cost of ppb-level methane gas detection is reduced.

Provided herein are methods for capturing a connected probe and / or a capture handle sequence to a capture domain of a capture probe.

The present invention relates to an electrode drying apparatus and an electrode drying method, and the electrode drying apparatus includes: an oven configured to provide a space in which the electrode is dried and to include a hot air nozzle or an infrared heater; a color coordinate measuring unit configured to be positioned at an outlet of the oven and measure a color coordinate value of an electrode active material layer with respect to the dried electrode; and a controller configured to analyze a drying result of the electrode from the color coordinate value, determine whether the electrode is defective in drying, and control a drying condition of the electrode.

The invention relates to the technical field of quartz sand detection, in particular to a quartz sand impurity detection method which comprises the following steps: acquiring spectral data of a quartz sand sample, and obtaining spectral line interference degrees of characteristic peaks according to energy distribution conditions of the characteristic peaks of the spectral data; based on the peak shape variation condition of each characteristic peak and the offset condition of each characteristic peak and a matrix characteristic peak, the matrix interference degree of each characteristic peak is obtained, and the interference intensity of each characteristic peak is obtained by combining the anti-interference degree of each characteristic peak so as to optimize the chaos regulation factor when the chaos mapping population is initialized; and finally, combining with an optimization algorithm to obtain a characteristic wave band with minimum interference, and detecting the purity and impurity content of the quartz sand based on the characteristic wave band. The quartz sand impurity detection precision can be improved.

Methods and systems for performing in situ decoding are described that minimize optical crowding, thereby improving decoding accuracy. The methods may comprise, e.g., receiving images of a biological sample acquired during a cyclical decoding process; detecting a series of detectable signals (ON signals) or absence thereof (OFF signals) at one or more locations in the biological sample corresponding to one or more barcoded target analytes; determining a code word based on the series of ON and OFF signals that corresponds to a barcode for each of the one or more barcoded target analytes, where the one or more code words are assigned to the one or more barcoded target analytes based on a minimax decision rule to minimize a density of ON signals detected in the images of the series of images; and identifying the one or more barcoded target analytes based on the one or more determined code words.

The invention discloses a lithium iron phosphate positive electrode material, a preparation method thereof and a lithium battery, and relates to the technical field of lithium ion batteries. According to the method, the pressing index of the lithium iron phosphate positive electrode material is tested by adopting a specific method, so that the pressing index meets a specific range, meanwhile, the average circularity of larger particles in a Dv50-Dv100 range meets a proper range, the lithium iron phosphate positive electrode material has better particle movement capability, and the particles can move at a higher speed to be rearranged during pressing, so that the particle size of the lithium iron phosphate positive electrode material is reduced, and the quality of the lithium iron phosphate positive electrode material is improved. Therefore, the positive pole piece with high compaction density can be obtained, the charge-discharge capacity of the battery can be improved, and meanwhile, the particles can be prevented from being broken when being pressed, so that the positive pole piece has good anti-pressure capability. By adopting the lithium iron phosphate positive electrode material provided by the invention, the lithium battery has relatively high energy density and capacity retention ratio.

Electroporation-based therapies (EBTs) employ high voltage pulsed electric fields (PEFs) to permeabilize tumor tissue, resulting in changes in passive electrical properties detectable using electrical impedance spectroscopy (EIS). Currently, commercial potentiostats for EIS are limited by impedance spectrum acquisition time (˜10 s); this timeframe is much larger than pulse periods used with EBTs (˜1 s). Fourier Analysis SpecTroscopy (FAST) is introduced as a methodology for monitoring tissue inter-burst impedance (diagnostic FAST) and intra-burst impedance (therapeutic FAST) during EBTs. FAST is a rapid-capture (<<1 s) technique which enables monitoring of inter-burst and intra-burst impedance during EBTs in real-time. FAST identified a frequency which delineates thermal effects from electroporation effects in measured impedance. Significance: FAST demonstrates the potential to perform EIS, in addition to intra-burst impedance spectroscopy, using existing pulse generator topologies.

A sensor system for optical detection of multiple analytes is discussed. An example system is presented that includes a plurality of lenses configured to receive individual light signals from analyte-sensing chromophores disposed on an array when the analyte-sensing chromophores are illuminated by light while being exposed to different specific analytes within an interstitial fluid. The system further includes at least one volume phase grating (VPG) communicatively coupled to at least one of the plurality of lenses and a detector communicatively coupled to the at least one VPG so that light signals from the analyte-sensing chromophores are focused by the plurality of lenses to the at least one VPG and transmitted to the detector. The detector being operable to generate spectra with each spectrum corresponding to an individual light signal from a single analyte-sensing chromophore.

In order to solve the problem that an existing high-voltage lithium ion battery is insufficient in high-temperature performance and safety performance, the invention provides a cyclic carbonate-sulfate compound and application thereof, a non-aqueous electrolyte and a secondary battery, and the cyclic carbonate-sulfate compound comprises a compound as shown in a chemical formula 1, the specific rotation [alpha] of the cyclic carbonate-sulfate compound ranges from-7.982 degrees mL / (dmg) to + 7.982 degrees mL / (dmg), and the specific rotation [alpha] of the cyclic carbonate-sulfate compound ranges from-7.982 degrees mL / (dmg) to + 7.982 degrees mL / (dmg); the chemical formula 1 of the # imgabs0 # is shown in the specification. When the cyclic carbonate-sulfate compound provided by the invention is used as an electrolyte additive, a formed solid electrolyte membrane is smoother and more ordered, so that the cyclic carbonate-sulfate compound has higher high-temperature stability, especially membrane layer stability under a thermal shock condition.

The present invention belongs to the field of sensors, and relates to an ion gel film with a microstructure on the surface, a preparation method, and an ion-type sensor. The preparation method comprises: sandblasting on a precursor substrate to obtain a substrate, forming a mixed solution of a polymer and an ionic liquid on the substrate to obtain a wet film, and drying and curing the wet film to obtain an ion gel film, wherein the precursor substrate has an arc-shaped recess array, and the sandblasting conditions include: the sandblasting particle size is 5000 mesh to 10000 mesh, and the sandblasting pressure is 2 bar to 10 bar. The ion gel film is used for an ion-type sensor, which can improve the detection sensitivity of the sensor.

The invention discloses a near-infrared emission aggregation-induced emission organic photo-thermal molecule and a preparation method and application thereof, and belongs to the technical field of biomedicine, and the structure is shown as a formula I: # imgabs0 # (I), wherein R1, R2, R3, R4, R5 and R6 are independently selected from groups containing alkyl chains. The invention also provides a preparation method of the organic photo-thermal molecule and application of the organic photo-thermal molecule in preparation of multifunctional protein nanoparticles with near-infrared aggregation-induced emission. The near-infrared emission aggregation-induced emission organic photo-thermal molecule provided by the invention shows excellent near-infrared imaging effect and photo-thermal capability under laser irradiation, and the obtained near-infrared aggregation-induced emission multifunctional protein nano particle has excellent photo-thermal effect and imaging resolution, has excellent targeting to brain tumor, and has good application prospects in blood brain barrier crossing, brain tumor targeting and brain tumor targeting. And tumor killing, photothermal and ferroptosis combined treatment has practical medical significance, and is expected to be widely applied to the aspects of intelligent drug delivery and nano medical treatment.

The invention provides a sodium ferric pyrophosphate positive electrode material cooperatively doped with anions and cations, a preparation method of the sodium ferric pyrophosphate positive electrode material and a sodium ion battery, and relates to the field of sodium ion batteries. The anion and cation synergistically doped ferric sodium phosphate pyrophosphate positive electrode material comprises an inner core and a coating layer covering the outer surface of the inner core, the inner core comprises ferric sodium phosphate pyrophosphate, the coating layer comprises carbon, the chemical formula of the ferric sodium phosphate pyrophosphate is Na4-2yFe2.91-xQx (PO4) 2-yP2O7Fy, x is more than 0 and less than or equal to 0.3, and y is more than or equal to 0.03 and less than or equal to 0.08; q comprises at least one of Sn, Ni, Cu, Mg and Mn. The introduced Q positive ions and F negative ions can keep the crystal structure of the body material stable, and the positive ions and the negative ions have a synergistic effect, so that the band gap of the positive electrode material is reduced, the state density near the Fermi level of the positive electrode material is increased, the conductivity of the positive electrode material is enhanced, the specific capacity of the positive electrode material is improved, and the rate and the cycle performance are promoted.

The invention relates to the technical field of optical signal processing, in particular to an optical signal processing algorithm based on biological agent fluorescence detection, which comprises the following steps: S1, collecting fluorescence signals with different wavelengths emitted by each probe, and generating a multi-channel fluorescence spectrum data set; s2, carrying out spectral de-mixing on the fluorescence signals in the fluorescence spectrum data set, separating a plurality of overlapped fluorescence signals, and decoupling the fluorescence signals with different wavelengths; s3, for highly overlapped fluorescence signals, carrying out secondary overlapping separation treatment on the fluorescence signals by using a nonlinear optimization method; s4, extracting the intensity, wavelength and time change characteristics of each fluorescent probe signal, and constructing a multi-dimensional fluorescent signal characteristic vector; and S5, by amplifying the characteristic peak value of the weak fluorescence signal, it is ensured that the signal is not covered by strong signals of other probes in multi-probe detection. According to the invention, the resolution of fluorescence detection is improved, so that the high-precision detection effect can be maintained under complex experimental conditions.

The invention relates to the technical field of quartz product measurement, and particularly provides a quartz product diameter measurer and a quartz product diameter measuring method, and the quartz product diameter measurer comprises a clamping mechanism, a moving table, a supporting guide mechanism and a laser outer diameter measuring mechanism. According to the invention, the clamping mechanism, the laser outer diameter measuring mechanism and the supporting and guiding mechanism cooperate with each other, so that the laser outer diameter measuring mechanism measures the diameter of the quartz rod in the circumferential direction in the process that the clamping mechanism drives the quartz rod to rotate axially; meanwhile, the mobile station drives the laser outer diameter measuring mechanism to move in the axial direction of the quartz rod through the supporting and guiding mechanism to measure the diameter, so that the diameter measurement of the quartz rod in the axial direction and the circumferential measurement of different axial positions are realized, the comprehensiveness of the diameter measurement of the quartz rod is improved, and the measurement result has representativeness; and the precision of diameter measurement of the quartz rod is improved.

The invention relates to the technical field of laser etching, and discloses a laser double-sided etching stress control method and system for a quartz crystal, and the method comprises the steps: generating a double-sided complementary etching path based on the initial stress distribution of the quartz crystal; and front and back laser energy input is synchronously controlled, so that a double-sided thermal stress field forms dynamic balance. And obtaining the stress gradient distribution of the etching area in real time based on spectral analysis. And according to the deviation value of the stress gradient and a target threshold value, a laser processing parameter combination is dynamically adjusted, and a morphology-stress coupling optimization mode is started in a final processing stage. By accurately controlling the thermal stress balance and the stress gradient distribution in the laser processing process, the residual stress of the quartz crystal can be effectively reduced, and the shape and the performance of the quartz crystal are optimized, so that the processing precision, the material stability and the device reliability are improved.

The invention discloses long-chain alkyl polyarylamine as well as a preparation method and application thereof. The structural formula of the long-chain alkyl polyarylamine is as shown in a formula (I): # imgabs0 # formula (I), wherein R is an alkyl group with the carbon atom number of 5-12, the weight-average molecular weight of the R is 5000-136000 g / mol, and the PDI of the R is 1.41-2.24; the long-chain alkyl polyarylamine provided by the invention has relatively high fluorescence intensity, can stably emit fluorescence at high temperature and under long-term illumination, and has relatively long fluorescence lifetime.

The invention relates to a bioelectrochemical sensor used for detecting hydrogen peroxide and a manufacturing method of the bioelectrochemical sensor. The novel bioelectrochemical sensor is a sensor with a three-electrode system, wherein the counter electrode is a platinum electrode, the reference electrode is saturated calomel electrode and the working electrode is gold electrode. The sensor is based on orientation combination of a polypeptide horse radish peroxidase with characteristic sequence, the promotion effect of the polypeptide horse radish peroxidase on the activity of the enzyme and the characteristic of high sensitivity of electrochemical detection methods. The sensitivity of hydrogen peroxide sensors is effectively improved and satisfactory results are obtained.

The invention aims to provide a method and a device for determining the peak area of chloride ions based on ion chromatography. The method for determining the peak area of chloride ions based on ion chromatography comprises the following steps: step 1, identifying a chromatographic peak: peak separation, peak qualitation, baseline correction, peak trailing treatment and peak overlapping treatment; and step 2, calculating the chromatographic peak area: peak definition, integration algorithm, calibration curve application, repeatability verification, impurity peak deduction and main peak area calculation. According to the method, a chromatographic peak identification and chromatographic peak area calculation mode is designed, so that the technical problem that other impurity ions may be introduced to influence chloride ion chromatographic peak identification and accurate area calculation in an existing mode of determining organic chlorine through ion chromatography is solved.

The invention relates to the technical field of secondary batteries, and particularly provides a positive active material, a positive pole piece, a secondary battery and an electric device. The positive electrode active material includes a lithium-containing phosphate and a lithium-containing metal oxide. Wherein the lithium-containing metal oxide accounts for 1%-20% of the positive electrode active material in percentage by mass. An X-ray diffraction pattern of the lithium-containing metal oxide comprises a diffraction peak of a crystal face (003) and a diffraction peak of a crystal face (104), the diffraction peak of the crystal face (003) and the diffraction peak of the crystal face (104) meet the condition that the value of I (003) / I (104) is smaller than or equal to 1.2, I (003) represents the intensity of the diffraction peak of the crystal face (003), and I (104) represents the intensity of the diffraction peak of the crystal face (104). The positive electrode plate comprises a current collector and a positive electrode film layer arranged on the current collector. The positive electrode film layer comprises the positive electrode active material. And the positive electrode active material accounts for 90-97% of the mass of the positive electrode film layer. The positive electrode active material provided by the invention can provide cycle performance of the secondary battery.

Embodiments described herein relate generally to electrochemical cells having semi-solid electrodes that are coated on only one side of a current collector. In some embodiments, an electrochemical cell includes a semi-solid positive electrode coated on only one side of a positive current collector and a semi-solid negative electrode coated on only one side of a negative current collector. A separator is disposed between the semi-solid positive electrode and the semi-solid negative electrode. At least one of the semi-solid positive electrode and the semi-solid negative electrode can have a thickness of at least about 250 μm.

The present invention relates to the technical field of lithium battery state estimation, and in particular to a fuzzy EKF-AH algorithm-based state of charge (SOC) estimation and correction method for a lithium iron phosphate battery. The method comprises: by taking a certain startup of an energy storage device as a start, a BMS reading an SOC and a state of health (SOH) at the previous shutdown, and on the basis of a standby time, selecting an open circuit voltage (OCV) or an EKF algorithm to correct the SOC; using an EKF-AH algorithm to estimate the SOC, establishing, on the basis of fuzzy control, a fuzzy rule library associated with the SOC and the SOH, and dynamically adjusting a weight and a measurement noise deviation of the EKF-AH algorithm; and calculating estimation differences between the EKF algorithm and an ampere-hour integration method, and if the sum of the estimation differences is greater than a corresponding threshold, issuing an SOH correction warning. The present invention improves the estimation accuracy of the entire life cycle of the lithium iron phosphate battery, and assists the correction of the SOH.

The invention discloses a lithium iron phosphate positive electrode material and a preparation method and application thereof, and belongs to the technical field of lithium iron phosphate positive electrode materials. The lithium iron phosphate positive electrode material comprises a lithium iron phosphate matrix and a carbon coating layer coating the surface of the lithium iron phosphate matrix, the average standard deviation of the thickness of a carbon coating layer in the lithium iron phosphate positive electrode material is # imgabs0 #, and sigma (d) is more than or equal to 0.05 nm and less than or equal to 0.35 nm; the average standard deviation of the carbon content in the lithium iron phosphate positive electrode material is sigma (Cwt%), and sigma (Cwt%) is larger than or equal to 0.02 wt% and smaller than or equal to 0.35 wt%. The lithium iron phosphate positive electrode material has a uniform carbon coating layer, and the thickness of the carbon coating layer and the carbon content at each position are relatively consistent, so that the improvement of the carrier mobility of the lithium iron phosphate positive electrode material is facilitated, and the further improvement of the electrochemical performance of a battery prepared from the lithium iron phosphate positive electrode material is facilitated.

To provide a sample analyzer capable of achieving shortening of a measurement time and improvement of efficiency, in an inspection using a reaction to a plurality of kinds of reaction substances whose measurement ranges are largely different.SOLUTION: A sample analyzer 1 includes: a measurement unit 23 as an imaging device for capturing an image including light reception information based on each reaction between a first reaction substance group comprising a plurality of kinds of reaction substances reacting to a component included in a sample and a second reaction substance which reacts to the component included in the sample and is a different type from a reaction substance included in the first reaction substance group; and a control unit 50 as a control device for analyzing, in the light reception information in the image, the light reception information on the basis of a first determination value corresponding to a first substance group and the light reception information on the basis of a second determination value corresponding to a second substance.SELECTED DRAWING: Figure 10

The invention relates to the technical field of lithium iron phosphate production, and discloses a carbon-coated titanium-doped lithium iron phosphate positive electrode material and a preparation method thereof.The preparation method comprises the following steps that 1, a ferrous solution and a phosphorus source solution are mixed in proportion, dopamine hydrochloride is added, a pH regulator is dropwise added in the stirring state, the pH of the solution is adjusted to 4.0-5.5, a reaction is conducted, a titanium source solution is added, and a reaction solution is obtained; after uniformly stirring, continuously dropwise adding a pH regulator to regulate the pH value of the solution to 5.5-6.5; the iron phosphate octahydrate coated with the titanium-embedded polydopamine is obtained; 2) calcining the titanium-embedded polydopamine-coated ferrous phosphate octahydrate in an inert gas atmosphere to obtain carbon-coated titanium-doped anhydrous ferrous phosphate; 3) mixing the carbon-coated titanium-doped anhydrous ferrous phosphate with lithium phosphate and a carbon source, ball-milling, mixing, spray-drying and calcining to obtain a carbon-coated titanium-doped lithium iron phosphate positive electrode material; the synthesis process is simple, and energy consumption is reduced.

The invention discloses a dry-method electrode film and a preparation method thereof, an electrode and a battery, and belongs to the technical field of batteries. The method comprises the following steps: mixing polytetrafluoroethylene, an active substance and a conductive agent, and crushing to obtain a crushed mixture; performing primary airflow grinding and shearing on the crushed mixture to obtain a ground and sheared mixture; the primary shearing conditions are as follows: the airflow temperature is-10 to 10 DEG C, the airflow pressure is 0.7 to 0.9 MPa, and the rotating speed is 8000 to 12000 rpm; carrying out secondary airflow grinding, shearing and fibration on the ground and sheared mixture to obtain a fibration material; and carrying out secondary fibration treatment on the fibration material to obtain the dry-method electrode film. The method can significantly improve the tensile strength of the electrode film, improve the liquid absorption rate of the electrode and reduce the resistivity of the electrode.

The invention discloses a lithium iron phosphate battery. The lithium iron phosphate battery comprises a positive electrode, a negative electrode, an isolating membrane and an electrolyte, a main material of the positive electrode comprises lithium iron phosphate, and a main material of the negative electrode comprises graphite and a silicon-based material; the surface density of the positive electrode is greater than or equal to 23mg / cm < 2 >, and the surface density of the negative electrode is greater than or equal to 7.8 mg The electrolyte comprises a lithium salt, a solvent and an additive, the solvent mainly comprises ethylene carbonate and a micromolecular linear solvent, the additive comprises FEC and a negative electrode film-forming additive, and a negative electrode film-forming agent comprises vinylene carbonate and a lithium salt additive; the mass fraction of the micromolecular linear solvent is 35%-60%, the mass fraction of the fluoroethylene carbonate is M, the mass fraction of the silicon element in the negative electrode layer is W1, M is greater than or equal to 2% and less than or equal to 2 * W1, and the mass fraction of the negative electrode film-forming agent is 4%-6%. The energy density of the battery cell can be improved and the cycle life and the quick charge capacity of the battery cell are both considered by doping a silicon-based material into the negative electrode, designing a thick electrode and adjusting an electrolyte formula.

The invention belongs to the technical field of sodium ion batteries, and particularly relates to a calcium ion doped modified sodium ion positive electrode material and a preparation method thereof, a positive electrode plate and a half battery. The calcium ion doped modified sodium ion positive electrode material comprises a sodium source, a doping source and a precursor, and is characterized in that the chemical general formula of the positive electrode material is Na < 1-x > M < x > Ni Fe Mn < c > O < 2 >, the value range of the doping sources M and x is x < = 0.05, a + b + c = 1, and all elements in the chemical formula meet charge balance. Sodium sites in a layered structure are replaced by calcium ion doping, so that interlayer spacing is enlarged, sodium ion transmission kinetics is enhanced, and adverse phase change is inhibited. The sodium ion positive electrode material shows high specific capacity and excellent cycle stability, the capacity retention ratio is 93.03% after 100 times of cycle charge and discharge at 1C, and the sodium ion positive electrode material has the characteristics of simple preparation, low cost, high specific capacity and excellent cycle performance.

The invention relates to the technical field of low-temperature adsorption and isotope separation, in particular to a low-temperature helium isotope adsorption separation system and a low-temperature helium isotope adsorption separation method, and the system comprises a gas distribution and gas recovery module which is used for preparing and mixing helium isotope raw material gas and recovering residual gas after an experiment; the static testing unit is used for testing the performance of the adsorbent under a fixed condition; the dynamic low-temperature adsorption unit is used for helium isotope separation under a continuous flow condition; the low-temperature control module is used for providing a stable low-temperature environment and accurate temperature control; wherein an air inlet pipe and an air outlet pipe of the low-temperature control module are respectively subjected to thermal sedimentation and are respectively connected with a flow controller. According to the scheme, the defects that in the prior art, He resources are seriously short, and existing low-temperature adsorption separation helium isotope examples are few are overcome, reference is provided for low-temperature adsorption separation helium isotope adsorbent screening and system design, development of the He separation and purification technology in China is promoted, and dependence on imported He is reduced.

The disclosure provides systems and methods for droplet processing. For example, a method can include providing a first droplet and a second droplet. In some cases, the first droplet may have a first concentration of a reagent and the second droplet may have a second concentration of the reagent. The second droplet may comprise a bead or a biological particle. The method can also include subjecting the first droplet and the second droplet to conditions sufficient to transfer the reagent from the first droplet to the second droplet, thereby decreasing the first concentration in the first droplet and increasing the second concentration in the second droplet.