17033 results about "Fluid phase" patented technology

The invention discloses an intelligent detection method for medicine components and medicine quality, and belongs to the field of artificial intelligence. The method comprises the following steps: acquiring a drug sample solution and a control drug solution, and injecting the drug sample solution and the control drug solution into a high performance liquid chromatography system; determining whether operation parameters of the high performance liquid chromatography system need to be adjusted or not; determining operation parameter adjustment information, and continuously updating operation parameters of the high performance liquid chromatography analysis system until a complete drug sample chromatogram and a complete control drug chromatogram are obtained; determining medicine component information and impurity component information of the sample medicine; and determining whether the sample medicine reaches a preset medicine quality evaluation standard or not according to the medicine component information and the impurity component information, and if the preset medicine quality evaluation standard is reached, determining that the sample medicine passes quality detection. According to the scheme, the manual operation time and personal errors can be reduced, the detection efficiency and accuracy are improved, and the analysis result is more accurate and stable.

The invention discloses a method for comprehensively identifying PFAS in an environment by combining targeted analysis, suspicious screening and non-targeted identification. The method comprises the following steps: S1, carrying out liquid chromatography-high resolution mass spectrometry fullscan / DDA / DIA analysis on an environmental sample; s2, carrying out liquid chromatography-high resolution mass spectrometry analysis on the plurality of PFAS standard substances; s3, according to a public chemical database and literature, collecting names and molecular formulas of a plurality of PFASs, calculating an accurate mass number, and jointly establishing a suspicious screening database in combination with an open-source MS2 spectrogram library; s4, establishing a non-targeted identification work flow by combining the mass number characteristics of the PFAS, the characteristic MS2 fragments, the characteristic neutral loss and the homolog characteristics; and S5, integrating the targeted analysis compound, the candidate compound subjected to suspicious screening and the candidate compound subjected to non-targeted identification, and comprehensively identifying the PFAS in the environmental sample. According to the method disclosed by the invention, the known and unknown perfluoroalkyl / polyfluoroalkyl compounds are fully identified through three complementary analysis technologies.

In general, the present invention is directed to a metal-organic framework (MOF) for use in removing liquid phase compounds, in particular anionic and cationic species, as well as a combination of anionic and cationic species, from a liquid or liquid stream. In addition, the present invention is directed to various methods or processes for utilizing the MOF to remove such compounds from a liquid or liquid stream, such as an industrial process stream, and for using the MOF at elevated temperatures.

A construction method for and a use of rhizoma pinellinae praeparata decoction piece, standard decoction and formula granule characteristic spectra. The construction method comprises the following steps: dissolving a test sample by using a solvent, and extracting to obtain a solution to tested; and measuring said solution by using high-performance liquid chromatography (HPLC) to obtain rhizoma pinellinae praeparata decoction piece, standard decoction and formula granule characteristic spectra, wherein chromatographic conditions of the HPLC are as follows: the chromatographic column is a C18 column; and gradient elution is performed by using acetonitrile as mobile phase A and a 0.1% phosphoric acid aqueous solution as mobile phase B. HPLC is used, gradient elution is performed by using acetonitrile and a 0.1% phosphoric acid aqueous solution as mobile phases, and 4-hydroxybenzoic acid is used as a reference object, so that rhizoma pinellinae praeparata decoction piece, standard decoction and formula granule HPLC characteristic spectra are established; the method has good repeatability and precision, is stable and reliable, and can control the quality of rhizoma pinellinae praeparata decoction pieces, a standard decoction and formula granules.

The invention discloses a gas self-excitation modulation device, an enhanced pollution aeration treatment system and an application method of the enhanced pollution aeration treatment system, through the arrangement of the gas self-excitation modulation device, intermittent modulation airflow matched with an orifice bubble generation process is formed, the instantaneous pulse acting force for upward separation of bubbles is increased, the bubble generation time is shortened, and the aeration bubble size is reduced; and the mass transfer rate of the gas-liquid interface is further improved. According to the invention, the existing laid aerator does not need to be replaced, the aerator material does not need to be modified, and the method is widely applicable to microporous aerators in any form; a water phase does not need to be driven to flow, so that energy consumption is greatly reduced, and adverse disturbance to a target water body is avoided; compared with a gas dissolving method and a jet flow air entraining method, the technology only drives a gas phase to enter a liquid phase, energy is saved, and meanwhile full-amount treatment of target liquid can be achieved. In addition, through sectional arrangement of the oscillation cavity self-excitation unit and the outflow unit, batch application can be carried out.

The invention belongs to the field of liquefied gas ships, and particularly relates to a gas test method of a liquefied carbon dioxide liquid cargo system for a ship. Comprising the following steps: drying a cargo hold space; liquid cargo tank and pipeline drying; pressurizing a liquid cargo pipeline; liquid cargo tank gas replacement; pressurizing the liquid cargo tank and the ventilation system; a liquid cargo tank cold tank; loading in a liquid cargo tank; testing the liquid cargo pump; unloading the liquid cargo tank; sweeping the liquid cargo tank; discharging the loading pipeline; heating the liquid collecting well; heating and ventilating the liquid cargo tank. According to the invention, the gas test process of the marine liquefied carbon dioxide liquid cargo system is simplified, and the operation efficiency is improved; before the liquid cargo tank gas replacement, pressurization and tank cooling are carried out, all the liquid phase pipelines are pressurized through dry gas, the gas test of the marine liquefied carbon dioxide liquid cargo system is carried out under the semi-cooling and semi-pressure condition, and the efficiency and safety of gas test operation are improved.

The invention discloses two brand-new bioactive peptides with antioxidant and alpha-glucosidase inhibitory activity in traditional Chinese medicine hippocampus. The sequences of the novel bioactive peptides provided by the invention are respectively YLPPNW and SVWLGGSLL. According to the method, purity and structure identification is carried out on the new bioactive peptide obtained through separation by adopting liquid phase, primary mass spectrum and secondary mass spectrum, and a material basis is provided for further quality control and drug effect research of the traditional Chinese medicine hippocampus.

A cooling system including an evaporator, a passive condenser, a heat exchanger, and a pump. The passive condenser is arranged in parallel with the heat exchanger relative to the fluid flow of a primary cooling medium. When a secondary cooling medium is provided to the heat exchanger, at least some of a primary cooling medium in the gas phase switches from being received by the passive condenser to the heat exchanger without operating any valves and supplies the primary cooling medium in the liquid phase to the evaporator. When the secondary cooling medium is not provided to the heat exchanger, the heat exchanger does not supply the primary cooling medium in the liquid phase to the evaporator. The pump is located in a liquid line fluidly connecting the evaporator to the passive condenser and the heat exchanger and pumps the primary cooling medium in the liquid phase to the evaporator.

The invention discloses a device and a method for producing oxamide, and relates to the field of chemical production. The method for producing oxamide specifically comprises the following steps: mixing a methanol solution of liquid ammonia and a methanol solution of dimethyl oxalate, carrying out ammonolysis reaction, carrying out flash evaporation, filtration and drying on first slurry obtained after the reaction is finished to obtain solid oxamide, and refining a liquid phase obtained by solid-liquid separation of the first slurry to obtain a byproduct methanol, ammonia in the tail gas is washed and absorbed by dimethyl oxalate and then returns to a reaction system. In the oxamide production process, dimethyl oxalate reacts with ammonia gas in mixed gas generated in the reaction process, and the obtained product is continuously subjected to subsequent ammonolysis reaction, so that the utilization rate of reaction materials is increased; meanwhile, a condenser is not used for condensing ammonia gas and methanol and then separating alcohol and ammonia, so that condensing equipment and cooling water are saved, the production cost is reduced, and industrial production is facilitated.

The invention discloses an efficient chemical liquid phase coating method of metal soft magnetic powder and application, and belongs to the technical field of preparation of soft magnetic materials, aluminum isopropoxide is dissolved to form a coating precursor solution, and an Al2O3 insulation coating layer is formed on the surface of the fluidized metal soft magnetic powder after hydrolysis and dehydration reactions. The aluminum isopropoxide is dissolved to form gel, the gel is uniformly mixed with the fluidized metal soft magnetic powder, dried gel can be formed on the surface of the metal soft magnetic powder after high-temperature airflow drying, and the dried gel is further calcined and dehydrated to form the high-insulativity Al2O3 coated metal soft magnetic powder. The method can be widely applied to surface insulation coating of the metal soft magnetic powder, has the characteristics of controllable coating layer thickness, simplicity, rapidness and high coating efficiency, and meets the requirements of industrial production such as large-scale, low-cost, safe and environment-friendly industrial production.

The invention provides a preparation method of an electrochemical biosensor based on a PLL-coated VPAu modified nuclear track membrane, and belongs to the field of electrochemical biosensing analysis. The electrochemical biosensor for detecting troponin is constructed by adsorbing a PLL (at) VPAu composite nanomaterial synthesized by an ultrasonic liquid phase assisted method into a nuclear track membrane pore channel through electrostatic interaction and connecting a specific recognition molecule of a target to the surface of the pore channel modified by the PLL (at) VPAu by utilizing a bonding reaction mechanism. After a target object is captured by the recognition molecules connected to the nuclear track membrane, the effective aperture of the nuclear track membrane nanopores is reduced, and the electrochemical workstation can convert the biological behavior into an electric signal, so that high-sensitivity and rapid detection of the target protein is realized. The method has very important theoretical and practical significance in the field of medical diagnosis, and a new direction is provided for application of the nuclear track membrane in the field of analysis and detection.

The invention relates to a composite phase-change film based on liquid metal and PBO fiber and a preparation method thereof, and belongs to the technical field of phase-change material preparation, and the preparation method comprises the following steps: the composite phase-change film comprises a poly (p-phenylbenzobisoxazole) fiber (PBO) base material, a phase-change material and a heat-conducting filler, the phase-change material is composed of phase-change microcapsules (PM) which are prepared by taking polyurethane (PU) as a wall material and organic solid-liquid phase-change materials (OPCMs) as a core material through a Pickering emulsion polymerization method. The prepared PM has a core-shell structure, and leakage of OPCMs is effectively prevented. The PM and the PBO fiber network are combined, so that the dual packaging of the OPCMs is realized, and the leakage of the OPCMs is further prevented. Meanwhile, dispersion and interaction of the OPCMs in a PBO matrix are optimized, and formation of a network structure with a limited domain is promoted. The composite phase change film prepared by the invention has relatively high mechanical properties, remarkable heat conductivity, excellent and stable flexibility and excellent heat storage capacity.

An immersion cooling system includes a work tank, a device to be cooled, and a heat conduction device. The work tank has a vapor section and a liquid-phase section. The liquid-phase section is adapted to contain a liquid-phase working fluid. At least one portion of the device to be cooled is in the vapor section. The heat conduction device includes a heat conduction element and a boiling-assisting structure. The heat conduction element has a first section and a second section. The first section is in the liquid-phase section, and the second section is connected to the at least one portion of the device to be cooled. The boiling-assisting structure is on the first section.

The invention discloses bone cement for orthopedic repair and a preparation method thereof, and relates to the technical field of bone cement. The bone cement for orthopedic repair comprises solid-phase powder and a liquid-phase component, the solid-phase powder comprises the following components in parts by weight: 55-65 parts of composite calcium phosphate, 10-15 parts of bioactive glass, 2-3 parts of a developing agent, 1-2 parts of hydroxyapatite, 8-12 parts of a modified toughening agent and 2-3 parts of nano cellulose fibers; the liquid phase component is prepared from the following components in parts by weight: 40 to 50 parts of a sodium alginate solution, 10 to 20 parts of methacrylated gelatin, 0.5 to 1 part of transglutaminase, 30 to 60 parts of a citric acid buffer solution and 1 to 2 parts of an antibacterial agent. The preparation method comprises the following steps: reacting pentaerythritol with 12-oxododecanoic acid to obtain an intermediate 1, and reacting the intermediate 1 with dopamine to prepare the modified toughening agent. The bone cement for orthopedic repair prepared by the invention has good mechanical, self-repairing and antibacterial properties.

The invention provides a method for synthesizing Cagrilintide by a large-fragment SPPS-LPPS mixing method. The method comprises the following steps: cutting the Cagrilintide into four polypeptide fragments, wherein sequences 1-14 are fragments I, sequences 15-26 are fragments II, sequences 27-35 are fragments III, and sequences 36-39 are fragments IV; coupling protected amino acid monomers at corresponding sequence positions one by one through SPPS to synthesize a full-protection fragment I, a fragment II and a fragment III, and synthesizing a fragment IV through a solid phase or a liquid phase; and carrying out repeated condensation / Fmoc removal reaction on the fragments by virtue of an LPPS (Liquefied Peptide Polystyrene) method, so as to obtain the fully-protected Cagrilintide. The total yield of synthesized Cagrilintide is about 45%, the purity is larger than 99.0%, the single impurity content is smaller than 0.1%, the process is simple, the production efficiency is greatly improved, and the method is more suitable for industrial production and has wide application prospects.

The invention discloses a process and a device for producing oxamide, and relates to the field of chemical production. The invention provides a process for producing oxamide, which specifically comprises the following steps: mixing a methanol solution of liquid ammonia and a methanol solution of dimethyl oxalate, carrying out ammonolysis reaction, carrying out flash evaporation, filtration and drying on first slurry after the reaction is finished to obtain solid oxamide, and carrying out liquid phase refining to obtain a byproduct methanol, ammonia in the tail gas is washed and absorbed by dimethyl oxalate and then returns to a reaction system. The methanol solution of dimethyl oxalate is used for absorbing excessive ammonia in the reaction process, and the reaction product is continuously used for producing oxamide, so that methanol and ammonia can be thoroughly separated, the conversion rate of ammonia can be greatly improved, and the economical efficiency of the production process is improved; meanwhile, tail gas containing ammonia is not discharged, and the environmental protection property of the production process is improved.

The invention relates to a multi-section quench trickle bed reaction system and reaction method for liquid phase hydrogenation of aldehyde and ketone, the system comprises a multi-section quench liquid phase hydrogenation reactor filled with at least two sections of catalyst bed layers, a product circulating liquid inlet is arranged above each section of catalyst bed layer and is used for introducing a product circulating liquid into the corresponding catalyst bed layer; the adiabatic temperature rise of each section of the catalyst bed layer of the reactor is independently controlled by controlling the flow and the temperature of the circulating quenching liquid of each section of the catalyst bed layer; the method can effectively reduce the adiabatic temperature rise of the catalyst bed layer, prolong the service life of the catalyst, reduce the occurrence of side reactions, improve the product quality and yield, reduce the circulation volume of the liquid-phase product, and reduce the energy consumption. And a better hydrogenation effect can be realized by adopting a single trickle bed reactor, so that the equipment investment is reduced.

The invention relates to the technical field of organic synthesis, and discloses a preparation method of bromo-pyrrole nitrile. The method comprises the following steps: (1) mixing p-chlorophenylglycine, acetonitrile, trifluoroacetic acid and a catalyst, then dropwise adding acyl chloride and carrying out acylation reaction, and after the reaction is completed, purging with an inert gas; (2) under the inert gas, mixing the mixture obtained in the step (1) with inorganic salt, then dropwise adding 2-chloroacrylonitrile, carrying out cyclization reaction, and separating a liquid phase from the obtained mixture; and (3) under the inert gas, mixing the liquid phase obtained in the step (2), hydrobromic acid and hydrogen peroxide, carrying out a bromination reaction, then extracting with acetonitrile to obtain an acetonitrile layer, then removing the acetonitrile, and then carrying out cooling crystallization to obtain the bromo-pyrrolenitrile. According to the technical scheme, the reaction yield is high, different solvents do not need to be frequently replaced, and the solvents can be recycled.

The invention relates to the technical field of sodium ion battery research and development, and particularly discloses a strong-oxidizing acidified asphalt-based hard carbon negative electrode material and a preparation method and application thereof, concentrated nitric acid or concentrated sulfuric acid is introduced into asphalt as a cross-linking agent, so that the cross-linking reaction among molecules can be promoted under a low-temperature condition, and the structural stability of the material is greatly improved. Compared with a traditional method, the method has the advantages that the technological process is simplified, only one-step pretreatment is needed before carbonization, and energy consumption and pollution caused by high temperature can be avoided. According to the liquid phase cross-linking strategy, through reconstruction of chemical bonds, the low-softening-point asphalt can form a more compact carbon precursor network structure at low temperature, and formation of a high-performance hard carbon material in the subsequent carbonization process is facilitated.

The invention discloses a steam compressor system and a control method. The system comprises a steam compressor, a controller, a heat exchange device, and a steam inlet pressure detection device, a steam exhaust pressure detection device and a steam flow detection device which are respectively connected with the controller, the heat exchange device internally comprises a gas phase area and a liquid phase area, and the gas phase area is communicated with a steam inlet of the steam compressor through a steam inlet pipeline; the steam inlet pressure detection device is arranged on the steam inlet pipeline; a heat exchange coil and a heating device are arranged in the liquid phase area; an inlet of the heat exchange coil is communicated with a steam outlet of the steam compressor through a steam exhaust pipeline; the steam exhaust pressure detection device and the steam flow detection device are arranged on the steam exhaust pipeline; an outlet of the heat exchange coil extends to the outside of the heat exchange device; and the controller is respectively connected with the steam compressor and the heating device. According to the steam compressor system provided by the embodiment of the invention, the steam heat can be recycled, so that the energy consumption of the steam compressor test is reduced, and the test cost is reduced.

The invention relates to a stable silk fibroin liquid condensation body, gel and a preparation method and application thereof, and belongs to the technical field of silk fibroin. The preparation method comprises the following steps: S1, dissolving silk fibroin in a lithium bromide solution, and then adding trypsin for incubation to obtain an enzyme-digested silk fibroin solution; and S2, performing low-temperature programmed centrifugal treatment including an induction stage, a nucleation stage and a liquid-liquid phase separation stage on the enzyme-digested silk fibroin solution, and cleaning to obtain the stable silk fibroin liquid-state aggregate, the method can reduce aggregate liquid drop aggregation and improve the particle size uniformity of the liquid drops.

The invention provides a method for synthesizing tirpotide by adopting a solid-liquid combination strategy. The preparation method comprises the following steps: firstly, respectively synthesizing full-protection peptide fragments (1-17) and (18-39), and then carrying out liquid-phase splicing and deprotection to obtain crude peptide; according to the strategy, the synthesis period can be remarkably shortened, large-scale industrial production is facilitated, meanwhile, the synthesis yield is high, and the purity and content of the obtained crude peptide are high.

An immersion cooling system includes a work tank, a buffer tank, and a communication control assembly. The work tank has a work-tank gas-phase region and a work-tank liquid-phase region. The buffer tank has a buffer-tank gas-phase region and a buffer-tank liquid-phase region. The communication control assembly includes a first pipeline, a first pump, a second pipeline, and a second valve. In response to that the first pump is actuated, through the first pipeline, a fluid of the work-tank liquid-phase region is transported to the buffer-tank liquid-phase region, or a fluid of the buffer-tank liquid-phase region is transported to the work-tank liquid-phase region. In response to that the second valve is actuated, through the second pipeline, the work-tank gas-phase region is selectively in communication with the buffer-tank gas-phase region.

The invention discloses a production method and a production device of an energy-saving sustainable aviation fuel, and the production method comprises the following steps: S1, adsorbing carbon dioxide in air by using an adsorbent, desorbing through high-temperature carrier gas, and cooling and compressing the desorbed carbon dioxide; s2, carbon dioxide and deionized water are preheated and then electrolyzed, and synthesis gas and oxygen are generated; s3, after the synthesis gas is compressed, performing Fischer-Tropsch reaction to generate a mixture of Fischer-Tropsch oil wax, light hydrocarbon and water, cooling and separating, and returning the Fischer-Tropsch reaction heat to preheat the synthesis gas; s4, pressurizing the Fischer-Tropsch oil wax, mixing the Fischer-Tropsch oil wax with hydrogen, carrying out hydrofining reaction to generate a gas-liquid isomerous oil-gas mixture, cooling and separating, and recycling heat energy of a product to And S5, after gas-liquid separation, preheating a liquid phase, carrying out rectification operation, separating and cooling to obtain a sustainable aviation fuel product. By recovering the heat in each link, the heat is efficiently utilized, and the energy-saving performance of production is improved.

The invention discloses a hydrocarbon fuel boiling point and quasi-critical parameter measurement and phase diagram drawing method. The method comprises the following steps: conveying a target substance to a calorimetric tube and heating the target substance to a target temperature; relevant parameters are monitored in real time; according to the parameters monitored in real time, the boiling point of the target substance is obtained based on heat transfer characteristics in the fluid phase change process; on the basis of an energy transfer model between the calorimetric tube and the fuel, a function of a target substance heat sink changing along with the temperature is obtained online; after the heat measuring pipe is cooled to the room temperature, the pressure is adjusted, and the steps continue to be executed to obtain functions of the boiling point of the target substance and the heat sink of the target substance changing along with the temperature under different pressures; based on a quasi-critical parameter measurement method, quasi-critical parameters of a target substance are obtained, and a P-T phase diagram of the target substance is drawn. The invention further discloses a device for hydrocarbon fuel boiling point and quasi-critical parameter measurement and phase diagram drawing. According to the method and the device, accurate measurement of the boiling point and the quasi-critical parameters and accurate drawing of the phase diagram can be realized.

The utility model relates to a salt cavern sediment gap energy storage simulation experiment device, and belongs to the technical field of salt cavern sediment gap energy storage experiment equipment. The salt cavern sediment gap energy storage simulation experiment device comprises two groups of normal pressure experiment containers, a pressure-resistant experiment container, a gas storage bottle, a water storage tank and a gas-liquid separator, the two groups of normal-pressure experiment containers are connected with each other through a communicating short circuit; the gas storage bottle is connected with a gas-liquid separator through a flow controller A and a gas injection valve A; one end of the gas-liquid separator is connected with the upper ends of the normal-pressure experiment container and the pressure-resistant experiment container through switch valves which are connected in parallel; and the outlet ends of the communicating pup joint and the pressure-resistant experiment container are respectively connected with a liquid phase pipeline through a control valve. The simulation experiment device is compact in structure and ingenious in design, solves the problems that in an existing salt cavern energy storage simulation experiment, an experiment under pressure cannot be carried out, and the experiment function is single, and is particularly suitable for being used in a salt cavern sediment gap energy storage simulation experiment.

The invention provides a preparation method of an h-BN / PI high-temperature-resistant anticorrosive coating, and relates to the technical field of polymer composites.The preparation method of the h-BN / PI high-temperature-resistant anticorrosive coating comprises the steps that under the protection of inert atmosphere, aromatic diamine containing impurity element five-membered rings and aromatic dianhydride containing ether bonds are taken and subjected to a polymerization reaction in a polar aprotic solvent, and the h-BN / PI high-temperature-resistant anticorrosive coating is obtained. A polyamide acid solution is obtained; performing ultrasonic-assisted liquid phase stripping on the micron-sized hexagonal boron nitride to obtain single-layer hexagonal boron nitride; adding the single-layer hexagonal boron nitride into the polyamide acid solution for multiple times, and uniformly stirring to obtain a hexagonal boron nitride / polyimide composite solution; and coating the hexagonal boron nitride / polyimide composite liquid on a to-be-coated surface, and carrying out gradient heating curing to obtain the h-BN / PI high-temperature-resistant anticorrosive coating. The h-BN / PI high-temperature-resistant anticorrosive coating based on interaction of multiple hydrogen bonds has relatively good high temperature resistance, relatively good resistance mechanical property and excellent corrosion resistance.

The invention provides a solid-liquid combined synthesis method of semeglutide, which belongs to the technical field of semeglutide synthesis, and specifically comprises the following steps: segmenting a main chain of the semeglutide into three shorter polypeptide fragments, namely a fragment 4, a fragment 5 and a fragment 2 at sites 7-14, 15-22 and 23-37, and respectively synthesizing at the same time; performing solid-phase assembly on the fragment 4 and the fragment 5 to form 7-22 peptide fragments, namely a fragment 1, and after the fragment 1 is cut off from the resin, forming NHS ester at a C end; after the fragment 2 is assembled, selectively removing a protecting group A11oc on the Lys26, then connecting with a side chain for fatty acid treatment to form a fragment 3, and cutting off the fragment 3 from the resin; and connecting the NHS ester of the fragment 1 with the fragment 3 in a liquid phase reaction system. The crude semeglutide prepared by the synthetic method is relatively high in yield and purity. The refined semeglutide of which the purity is more than 99.3% and the content of single impurity is less than 0.1% can be obtained at high yield through a conventional purification means.

The invention relates to the technical field of liquid chromatography-mass spectrometry series connection, and particularly discloses a method for detecting folic acid metabolites of red blood cells through the liquid chromatography-mass spectrometry series connection technology. And an image analysis algorithm based on artificial intelligence and deep learning is utilized to extract a chromatographic separation state, so that gradient parameters are dynamically adjusted, the requirement of manual intervention is reduced, and the separation process of a target object in a complex matrix is favorably optimized. Particularly, key features in a chromatogram can be automatically identified and quantified based on a deep learning method, and gradient elution parameters are intelligently and dynamically adjusted according to the information, so that more optimized substance separation and detection can be realized. For example, if separation of a certain component is not ideal, the separation effect of the component can be improved by adjusting the proportion of the mobile phase B, so that the gradient elution process is optimized.

The invention provides a preparation method of a general flavone extract in abelmoschus manihot flowers, which comprises the following steps: A) crushing the abelmoschus manihot flowers, extracting with an alcohol solvent, filtering, and concentrating to obtain an extracting solution; b) purifying the extracting solution by adopting macroporous resin to obtain an eluent; and C) concentrating the eluent, and drying to obtain the traditional Chinese medicine composition. According to the method, diluted alcohol extraction and a high-speed homogenization-ultrasonic-assisted liquid phase extraction method (HSH-UAE) are adopted, so that the contact area of a solvent and the abelmoschus manihot flowers is increased, full contact of medicinal materials and the solvent is guaranteed, and flavonoid substances are dissolved more sufficiently, so that the extraction speed is increased, and the extraction efficiency is improved. Macroporous adsorption resin is selected for separation and purification, the purification effect is good, operation is easy, safety, no toxicity and no pollution are achieved, reuse can be achieved after slight treatment, and the production cost is effectively reduced. Compared with a traditional method, the method has the technical advantages that the extraction speed is high, the extraction yield is high, effective components are fully extracted and reserved, and the process is simple.