91 results about "Electrostatic interaction" patented technology

This invention discloses a trimethyl chitosan-hyaluronic acid-FMNL2 siRNA nanomedicine and its applications. The siRNA molecule consists of a sense strand and an antisense strand, which are anti-complementary to form a double-stranded RNA structure. Each of the sense and antisense strands independently contains two pendant deoxythymidines at its 3' end. The nanomedicine uses trimethyl chitosan as its core framework, efficiently encapsulating the siRNA molecule through electrostatic interactions, and then modifying hyaluronic acid through electrostatic interactions to form core-shell structured nanoparticles. This invention forms a complete technology chain from target validation, siRNA sequence design, nanodelivery system construction, in vivo and in vitro efficacy verification to the development of combination drug strategies. It also provides quantifiable efficacy evaluation biomarkers, offering a clear basis for clinical patient screening and efficacy monitoring.

The present application relates to the technical field of medicine, in particular to a kind of siRNA eye drop for penetrating mucus barrier and cell barrier and preparation method thereof.Innovative development side chain guanidino group-containing polydisulfide delivery carrier is used in the present application, through the quick dynamic disulfide exchange reaction between polydisulfide and sulfhydryl on mucin, tear film retention and efficient penetration are realized, and cationic polydisulfide is quickly adsorbed on the surface of negative charged cell membrane by electrostatic interaction, the quick dynamic disulfide exchange reaction between polydisulfide and sulfhydryl on cell membrane is used, and endocytosis is used to quickly penetrate tight junction cell layer.

The present application relates to a kind of preparation method of antibacterial functional complex with stable structure, impregnation liquid, impregnated paper and veneer, belong to antibacterial functional material and artificial veneer technical field.The core of the present application is to prepare a kind of high-temperature-resistant antibacterial functional complex, its method is as follows: tea polyphenol, liquorice extract and citric acid are compounded, then mixed with gelatin solution, then compounded with chitosan under pH 5.0~6.0 by electrostatic interaction, finally crosslinked by glutamine transaminase catalysis, form "electrostatic-covalent" dual stable network structure.The structure effectively encapsulates natural antibacterial active ingredient, so that it can withstand the high-temperature process of impregnation drying and hot pressing, effectively avoid decomposition.The complex is added as additive in impregnated resin, antibacterial impregnated paper and veneer can be prepared.The product has efficient, long-acting, safe antibacterial function, and the preparation process is compatible with existing impregnated paper production line, easy to realize industrial production.

This invention discloses a layer-by-layer deposition modified ultrafiltration membrane with both antifouling and antibacterial properties, its preparation method, and its applications. Through layer-by-layer assembly technology, a tannic acid (TA) anion layer and a polyhexamethylene biguanide (PHMB) cation layer are alternately deposited on the surface of an ultrafiltration membrane. Under weakly alkaline conditions, electrostatic interactions, hydrogen bonding, Schiff base reactions, and Michael addition reactions are simultaneously utilized to achieve both non-covalent and covalent bonding, constructing a stable and dense integrated antibacterial-antifouling composite coating. This coating has a contact-type antibacterial structure, which can effectively kill bacteria in water and inhibit biofilm formation at the source. Simultaneously, it significantly improves the hydrophilicity of the membrane surface, reduces pollutant adsorption and deposition, and achieves synergistic enhancement of antibacterial and antifouling properties. The preparation process of this invention is mild, simple, low-cost, and environmentally friendly. The modified membrane exhibits high flux retention, excellent separation performance, and excellent operational stability, and can be widely applied in water treatment scenarios such as municipal wastewater treatment.

The application discloses a preparation method and application of a double-layer COF composite membrane and belongs to the technical field of gas separation membranes. The double-layer COF composite membrane is prepared by the following steps: taking a porous polymer membrane as a support layer, depositing macroporous TpBD-2SO3H nanosheets on the surface of the base membrane through vacuum suction filtration, and interfacially polymerizing a microporous ACOF-1 layer. The application induces ACOF-1 to be generated on the surface of the TpBD-2SO3H nanosheets through electrostatic interaction between the TpBD-2SO3H nanosheets and amine monomers, and a dense and defect-free composite membrane is obtained, which exhibits excellent H2 / CO2 separation performance. The method is ingeniously designed, and the double-layer COF composite membrane prepared by the method has important application potential in the field of H2 separation.

The application provides a chlorogenic acid-europium nanoparticle and a preparation method and application thereof, and belongs to the technical fields of nanobiological materials and biological medicine. The preparation method of the chlorogenic acid-europium nanoparticle comprises the following steps: slowly mixing chlorogenic acid (CGA) and europium ions in a solvent, and self-assembling the CGA-Eu (Eu 3+ ) nanoparticles through intermolecular coordination, electrostatic interaction and hydrophobic effect. The CGA itself has good biomedical application potential, the addition of the europium ions causes coordination with the CGA to enhance the stability of the CGA and enrich the functions of the CGA. The CGA-Eu nanoparticles have good stability under physiological conditions, and can conditionally release the CGA and Eu 3+ ions under pathological microenvironments, and have multiple effects of antioxidation, anti-inflammation, antibiosis and promotion of angiogenesis, and excellent biocompatibility. The nanoparticles obtained through the method of the application solve the problem of instability of the chlorogenic acid under conventional environments, and have wide application prospects in the fields of biological medicine, health products and cosmetics.

To solve the problem that the existing binder cannot stably constrain the volume expansion of the negative active material, the application provides a negative electrode binder, a negative electrode sheet and a secondary battery. The negative electrode binder comprises a polymer and a hydrogen bond acceptor containing a quaternary ammonium salt, the polymer comprises an acrylic structural unit, a zwitterionic structural unit and a crosslinking structural unit, and the zwitterionic structural unit comprises a cationic group with a positive charge and an anionic group with a negative charge. In the application, the positive and negative charge groups of the zwitterionic structural unit form a double anchoring mechanism, the cationic group anchors the anion of the hydrogen bond acceptor through electrostatic interaction, and the anionic group produces ion-dipole interaction with the quaternary ammonium cation of the hydrogen bond acceptor, so as to firmly lock the hydrogen bond acceptor in the polymer network. The anchored hydrogen bond acceptor can reconfigure the original rigid hydrogen bond network of the polymer, form a dynamic hydrogen bond network, significantly improve the flexibility and stress buffering capacity of the binder, and inhibit the volume expansion of the negative active material.

The application discloses a kind of Pd single atom modified two-dimensional WO3 Nanosheet for hydrogen rapid detection under high humidity, preparation method and application, the material is synthesized by electrostatic assembly method, using chelating agent to the surface modification of WO3 Nanosheet, subsequently join Pd species, cleverly utilize the electrostatic interaction between Pd species and WO3 surface, so that the migration of Pd species in the prepared material can be effectively controlled when high temperature treatment, finally obtain the Pd single atom modified two-dimensional WO3 Nanosheet material for hydrogen rapid detection under high humidity.The sample prepared by the application improves the selectivity and sensing stability to hydrogen, even under high humidity conditions (90%RH), 20ppm hydrogen still has good gas sensitive sensing performance (2250) at working temperature of 100 DEG C.

This invention discloses a nano-bandage for preserving cut flowers, belonging to the field of horticultural technology. The nano-bandage consists of a polymer carrier and a bactericide encapsulated therein. The polymer is a mixture of PEG and PDMAEMA. By adjusting the mass fraction and total concentration of PDMAEMA, the particle size of the nanoparticles can be controlled, and their surface can be positively charged. It is prepared using microfluidic co-assembly technology, where the drug-containing organic phase and aqueous phase are instantaneously mixed and purified by dialysis. This nano-bandage actively targets and persistently accumulates on the negatively charged cut surface of fresh cut flowers using electrostatic interactions, forming a physical barrier. It also synergistically inhibits microbial infection through slow-release bactericide and charge adsorption, while its nano-size does not affect vascular function. This invention achieves precise and long-lasting protection for cut flower wounds, significantly extending vase life with extremely low dosage, and has the advantages of high efficiency, safety, and intelligent adjustability.

This invention discloses a method for determining the concentration of sulfated glycosaminoglycans using fluorescence spectroscopy. The fluorescent probe carries a certain number of arginine residues. Utilizing the electrostatic interaction between the amino groups on the arginine residues and the sulfate ions on the sugar chains, a series of fluorescent probe molecules can align neatly along the sugar chains to form a stable fluorescent complex. Due to the small spatial distance between the fluorescent chromophores in the complex, the original fluorescence emission band shifts. By calculating the ratio of the fluorescence intensities at two points, the concentration of sulfated glycosaminoglycans can be determined. This invention provides accurate detection results, good reproducibility, and high sensitivity; the experimental materials are simple, saving a significant amount of time.

This invention belongs to the field of electrochemical energy storage materials technology, and provides an amphoteric composite binder, its preparation method, and its application in the positive and negative electrodes of lithium batteries. The binder is prepared by copolymerization of carboxyl-containing monomers and amphoteric monomers, and a dynamic cross-linked network is constructed through hydrogen bonding and electrostatic interactions. The composite binder enhances the interfacial bonding strength between the electrode and the current collector, as well as between the electrode active particles, and promotes ion transport through the interaction between the electrolyte and the lithium salt, thus improving ion transport performance. Simultaneously, during battery charging and discharging, the dynamic network structure can mitigate stress caused by volume changes, thereby improving electrode structural stability. The composite binder is suitable for electrode material systems with high volume changes, such as silicon-based negative electrodes and sulfur-based positive electrodes, helping to improve battery cycle stability and capacity retention, and exhibits good compatibility in various electrolyte systems.

The application provides a silk fabric sensor and application thereof in gesture recognition, and belongs to the technical field of flexible electronics and wearable sensing. X MXene nanosheets are functional fillers, and Ti X MXene nanosheets are loaded on the surface of silk fibers through an immersion coating process to form a core-shell structure conductive fabric, and Ti X MXene and silk fibroin are stably combined through a hydrogen bond network and electrostatic interaction, the water vapor transmission rate of the sensor is more than 2000 g / m²・day, the sensitivity coefficient GF in the low strain region of 0-18% is 149.31, and the sensitivity coefficient GF in the high strain region of 18-32% is 24.57. X MXene nanosheets are functional fillers, and stable combination of MXene and silk fibers is realized through optimization of a preparation process, so that the application has high sensitivity, good air permeability and excellent fatigue resistance, and a high-precision and low-delay gesture recognition and human-computer interaction system is constructed.

This invention discloses a flame-retardant coating, its preparation method, and its application, belonging to the field of coating material preparation technology. The preparation method of the flame-retardant coating includes: dissolving anionic polysaccharides in water, adding urea and phosphoric acid, reacting at 90-100℃ for 8 h to obtain phosphorylated modified polysaccharides, then adjusting the pH of the modified polysaccharides to 6-8 with an aqueous solution of cationic polypeptides, mixing them in equal volumes, and centrifuging to collect the reaction products, thus obtaining the flame-retardant coating. This invention uses biomass-derived polysaccharides and polypeptides as a basis, introducing flame-retardant groups through phosphorylation modification of the polysaccharides, and then utilizing the strong electrostatic interactions and hydrogen bonding between anions and cations to construct a three-dimensional network aggregate. This method is simple, mild, and low-cost. The prepared coating possesses both excellent flame retardancy and high adhesion, and can be widely used in the field of fireproof materials.

The application discloses a mussel-mimic bacterial-responsive injectable hydrogel and a preparation method and application thereof, and belongs to the technical field of biological medicines. The hydrogel is composed of a mussel-mimic viscous hydrogel support and a bacterial response agent; the viscous hydrogel support is QCS-EC, which is formed by non-covalent combination of quaternary ammonium chitosan QCS and epigallocatechin gallate EGCG; and the bacterial response agent is a supramolecular nanometer cross-linking compound TEBox-B 12， which is self-assembled by hydrogen bonds and electrostatic interactions. 12 H 12 2‑ The hydrogel of the application has NIR-II photothermal and photodynamic antibacterial treatment functions, can realize efficient killing of bacteria in deep tissues, has high adhesion, good biocompatibility and injectability, is convenient and applicable, can provide a good healing environment for a wound, promotes fibroblast proliferation and migration, accelerates wound tissue regeneration and healing process, and reduces scar formation.

This application provides a biantibody-modified vesicular STING agonist, its preparation method, and its application, relating to the field of polymer nanomedicine technology. The biantibody-modified vesicular STING agonist in this application includes vesicles, a STING agonist, and biantibodies. The vesicles are formed by cross-linking and assembling functionalized amphiphilic block polymers, and their lumens are negatively charged. The STING agonist is loaded into the vesicle lumen by electrostatic interactions. The biantibodies include anti-HER2 monoclonal antibodies and anti-PD1 monoclonal antibodies grafted onto the surface of the vesicles. The biantibody-modified vesicular STING agonist exhibits good biocompatibility and can enhance the killing effect of T cells on tumor cells, thereby killing tumor cells.

This application provides a conductive paste and its preparation method, an electrode, and a battery, belonging to the field of battery technology. The conductive paste includes carbon nanotubes, a dispersant, a dispersing aid, and a hydrophilic solvent. The dispersant includes at least one of cellulose derivatives, polyurethane and its derivatives, polystyrene derivatives, and polypolyols and their derivatives. The dispersing aid includes at least one of lactams, small molecule esters, small molecule chain amides, and small molecule alcohols and their derivatives. The dispersant molecules of this application are easily adsorbed onto the surface of carbon nanotubes to generate electrostatic interactions. At the same time, its polymer chains also hinder the aggregation of carbon nanotubes, thereby achieving the unbundling of carbon nanotubes. Simultaneously, the unbundled carbon nanotubes are uniformly dispersed in the solvent. The dispersing aid can be uniformly dispersed in the solvent and interact with the surface of carbon nanotubes, reducing the surface energy of carbon nanotubes, further promoting their dispersion, and preventing the carbon nanotubes from re-aggregating, resulting in a conductive paste with low entanglement and low viscosity.

The application belongs to the technical field of battery preheating, and particularly relates to a fast-response in-situ temperature control binder as well as a preparation method and application thereof. The application proposes a new binder, which uses hyperbranched polymers carrying a large number of charges to load fast-response particles through electrostatic interaction and redox reaction, and designs an external miniature heating device cooperating with the fast-response binder, so that the impedance of the battery is not increased, and the effect of non-contact fast heating of the battery interior can be achieved only by using the binder when assembling the battery and cooperating with the external device. The battery can be raised from minus 60 degrees Celsius to room temperature in 5 seconds, and the battery in hibernation due to low temperature can be quickly woken up to discharge and work again. The application has great significance for the field of battery low-temperature preheating, and provides a brand-new heating strategy, which creates an unprecedented new idea for the use of the battery at low temperature.

This invention relates to the field of coating technology and discloses a water-based anti-corrosion coating for air conditioning and its preparation process. The water-based anti-corrosion coating of this invention comprises 90-130 parts by weight of water, 100 parts by weight of water-based acrylic resin, and 0.5-2 parts by weight of cationic polyvinyl alcohol fiber, etc. The quaternary ammonium salt cationic groups of polyvinyl alcohol fiber and the carboxyl anionic groups in water-based acrylic resin form an electrostatic interaction. After curing into a paint film, polyvinyl alcohol and acrylic resin form a tight cross-linked network, which can inhibit the entry of corrosive media into the paint film, resulting in better anti-corrosion and salt spray resistance. Furthermore, the compatibility between the two is improved, the impact resistance and pencil hardness of the paint film are increased, and the mechanical properties are improved. It has good practical applications in air conditioning outdoor unit casings, heat exchanger fins, etc.

This invention discloses a method for preparing and applying a coumaric acid-modified MOF nanopesticide loaded with chlorantraniliprole, belonging to the field of pesticide formulation technology. The nanopesticide comprises: an iron-based metal-organic framework carrier MIL-101(Fe); chlorantraniliprole loaded within the pores of the carrier; and coumaric acid modified on the surface of the carrier through electrostatic interactions. The preparation method includes three steps: MIL-101(Fe) carrier synthesis, chlorantraniliprole loading, and coumaric acid surface modification. The process is simple and the conditions are mild. This invention utilizes the alkaline environment of the fall armyworm's gut to trigger carrier degradation, achieving targeted and controlled release of active molecules. Simultaneously, the released MIL-101(Fe) is reduced under the action of GSH in the gut, generating reactive oxygen species through the Fenton reaction, forming a synergistic insecticidal effect with coumaric acid. Experiments have shown that this nanopesticide exhibits far superior insecticidal activity against fall armyworm compared to single agents or carriers, possessing excellent insecticidal activity and environmental compatibility, making it suitable for green agricultural production.

This application discloses an analytical method for electrolyte systems based on low-scaling Monte Carlo simulations of electrostatic interactions, relating to the field of molecular simulation technology. The method includes: constructing an initial model of the target system and configuring simulation parameters; initializing local electric displacement auxiliary field variables; using these variables to describe the local electric displacement state of the target system; randomly selecting and updating an object; the updated object being the particle configuration and / or the local electric displacement auxiliary field variables; determining the equivalent local electric field strength at the target spatial location after updating the object; updating the local dielectric constant at the target spatial location based on the equivalent local electric field strength; and after updating the local dielectric constant, determining the various electrostatic interaction energies in the target system and evaluating the total electrostatic energy. This method can accurately describe the complex electrostatic interactions between components caused by local electric fields, high charge density, and the dielectric response properties of the components while ensuring computational efficiency.

This invention discloses a porous liquid stabilized by LDH interface engineering, its preparation, and its application. The porous liquid comprises mesoporous SiO2@LDH composite nanoparticles and an ionic liquid. The mesoporous SiO2@LDH composite nanoparticles have a composite structure formed by the self-assembly of mesoporous silica and layered bimetallic hydroxide nanosheets, with the layered bimetallic hydroxide nanosheets serving as the interface layer. The ionic liquid and the LDH surface –OH groups exhibit hydrogen bonding and electrostatic interactions. This invention solves the problems of weak electrostatic bonding, poor mass transfer due to pore closure, and high solvent toxicity in existing technologies. By constructing a SiO2@LDH composite material and obtaining mesoporous SiO2@LDH through alkali treatment followed by etching, the LDH nanosheets achieve a dual-functional interface, unifying pore protection and system stability. It exhibits high adsorption capacity, good selectivity, and excellent regeneration performance in CO2 capture.

This invention discloses a method for preparing and applying a Z-type heterojunction ZnCdS / NiFeLDH composite catalyst for hydrogen evolution through photoreforming of waste plastics coupled with water decomposition, relating to the field of photocatalyst technology for hydrogen evolution through water decomposition. The invention involves ultrasonically dispersing NiFeLDH in anhydrous ethanol solution, followed by ultrasonically dispersing ZnCdS nanoparticles; thoroughly stirring the mixture to form a Z-type heterojunction ZnCdS / NiFeLDH through electrostatic interaction; washing the mixture several times by centrifugation with ethanol; and drying the resulting yellow powder to obtain a powdered Z-type heterojunction ZnCdS / NiFeLDH composite catalyst. The preparation method of this invention is simple, the reaction conditions are mild, and it is economical, efficient, and environmentally friendly. The resulting composite catalyst exhibits excellent catalytic performance, efficiently decomposing water to generate hydrogen, and maintains good performance and stability even after multiple cycles of recycling.

This invention discloses a nanoparticle loaded with α-dextrin and Lycium barbarum polysaccharide, its preparation method, and its application. A nanoparticle carrier is prepared using chitosan and whey protein isolate, or chitosan and bovine serum albumin, as raw materials. The nanoparticles loaded with α-dextrin and Lycium barbarum polysaccharide are then prepared using the nanoparticle carrier, α-dextrin, and Lycium barbarum polysaccharide as raw materials. Using chitosan and whey protein isolate as carrier materials, composite nanoparticles are formed through electrostatic interactions and hydrogen bonding. The excipients are safe, the manufacturing process is simple, and the nanoparticles can simultaneously encapsulate the hydrophobic drug α-dextrin and the water-soluble drug Lycium barbarum polysaccharide, achieving efficient co-loading of two drugs with different solubility properties. The resulting nanoparticles have uniform particle size and good dispersibility. This invention constructs a nano-co-delivery system with dual antibacterial and anti-inflammatory functions, capable of simultaneously delivering two drugs to the site of infection for synergistic therapeutic effects.

The application provides a biodegradable antibacterial medical adhesive and a preparation method and application thereof, and belongs to the technical field of biomedical materials and medical devices. The antibacterial medical adhesive is obtained by forming a double cross-linking network hydrogel through Schiff base reaction, electrostatic interaction and hydrogen bond of chitosan guanidine salt, aldehyde-based dextran and tannic acid, and specifically, 0.1-30wt% aldehyde-based dextran aqueous solution and 0.1-25wt% tannic acid aqueous solution are mixed to obtain a mixed solution, then 0.1-30wt% chitosan guanidine salt aqueous solution is added into the mixed solution, and uniform mixing is carried out at room temperature. The tannic acid is introduced on the basis of the chitosan guanidine salt and aldehyde-based dextran to further enhance the adhesion effect, hemostasis, antibacterial and antioxidant properties, and the antibacterial medical adhesive has the advantages of no biological toxicity and can be biodegraded and absorbed.

The invention discloses an enzyme functionalized sensor for detecting nano plastic DPV in a biological matrix as well as a preparation method and a detection method of the enzyme functionalized sensor, and belongs to the field of nano plastic detection. The sensor comprises an electrode and CAT enzyme, wherein the surface of the electrode is modified with positively charged nano-gold particles, and the CAT enzyme is fixed through positive and negative electrostatic interaction. According to the sensor, the CAT enzyme and the nano plastic are combined to generate conformational change to change the activity of the CAT enzyme so as to cause DPV signal change, the sensitivity is high, the sensor has similar DPV signal response to different types of nano plastic, and a unified calibration model can be utilized to detect a complex biological matrix system so as to realize total amount determination of various nano plastic. And the electrochemical detection method does not need complex instruments and pretreatment, and provides a rapid, economic and extensible detection scheme for nano plastic exposure evaluation and environmental monitoring.

The application provides a positive electrode material, a preparation method thereof, a positive electrode and a lithium ion battery. The positive electrode material comprises acid-modified lithium manganese iron phosphate and a coating layer coated on the surface of the acid-modified lithium manganese iron phosphate; and the material of the coating layer comprises an amphiphilic compound, and the amphiphilic compound comprises a cetyltrimethylammonium trimeric tungsten phosphate. In the positive electrode material, the acid-modified lithium manganese iron phosphate and the amphiphilic compound are connected through strong electrostatic interaction, so that the amphiphilic compound is uniformly distributed on the surface of the acid-modified lithium manganese iron phosphate, and the amphiphilic compound and the acid-modified lithium manganese iron phosphate form a hybrid nanostructure, thereby making the positive electrode material have higher reversibility, faster rate performance and more stable cycle performance.

This invention discloses a gellizable, dynamically adhesive, moist wound healing dressing and its preparation method and application. The dressing is constructed from water-soluble cellulose derivatives, chitosan derivatives, and silk fibroin through physical cross-linking and freeze-induced phase separation, achieving dry-state stability without the need for chemical cross-linking agents. Upon contact with wound exudate, a gel layer forms. With prolonged contact, the carboxyl, amino, and hydroxyl functional groups form a dynamic, reversible hydrogen bond and electrostatic interaction network with skin surface proteins, resulting in an adhesion interface strength lower than the external force required for peeling, thus achieving non-damaging peeling. Furthermore, the dressing possesses antibacterial properties and acts as a nutrient substrate to promote cell proliferation and tissue regeneration. This invention's dressing integrates gelation, moisturizing, dynamic adhesion, antibacterial, and nutritional healing functions, making it suitable for moist wound healing treatment of various skin wounds and providing a novel dressing for clinical wound care.

The application discloses an ionic soft matter system low-scale molecular dynamics simulation method and a related device, and belongs to the technical field of molecular dynamics simulation. The method comprises the following steps: performing coarse-grained modeling on each component in an ionic soft matter system to be simulated; the components comprise ions and polar components; under the coarse-grained modeling framework, an interaction representation mode based on a dipole moment is introduced, the polar components are modeled in the form of an equivalent dipole moment, and a coarse-grained interaction model is obtained; and molecular dynamics simulation is performed according to the coarse-grained interaction model, and simulation results are obtained. At the theoretical level, the application replaces explicit positive and negative point charges with a dipole moment to describe molecular polarity, and at the simulation level, a coarse-grained molecular dynamics algorithm is introduced to represent the interaction of the polarity effect with the dipole moment. The method significantly reduces the calculation scale by reconstructing the form of electrostatic interaction, improves the simulation efficiency while retaining the key physical mechanism.

Provided is an ink composition that is excellent in bleed prevention and wiping resistance and is suitable for industrial production. The present invention relates to a composite coloring particle including a resin particle having a positive charge on the surface of the particle and a pigment particle having a negative charge on the surface of the particle, the aforementioned resin particle and the aforementioned pigment particle being complexed by electrostatic interaction, and an aqueous ink composition in which the aforementioned composite coloring particle is dispersed in an aqueous medium, and a writing instrument equipped with the aforementioned aqueous ink composition. Furthermore, the present invention relates to a method for producing a composite coloring particle, including a complexing step of mixing a resin emulsion including a resin particle having a positive charge on the surface of the particle and a pigment dispersion including a pigment particle having a negative charge on the surface of the particle.

Disclosed herein are systems and methods for producing structural color in layer-by-layer assemblies of Ti3C2Tz MXene nanosheets and polyelectrolyte heterostructures with controlled block thicknesses. In an aspect, the block thickness and spatial placement of MXene is controlled by the assembly's salt concentration and number of layer pairs. In a further aspect, to achieve controllable thicknesses in MXene blocks a processing method called layer-by-layer (LbL) assembly is employed. LbL assembly uses electrostatic interactions to alternately deposited layers of desired materials. In a still further aspect, layers of desired thicknesses can be built up by sequential deposition, allowing the creation of MXene blocks of specific thicknesses in order to attain structural color.