556 results about "Microbubbles" patented technology

The invention belongs to the technical field of film quality analysis and evaluation, and particularly relates to a flexible circuit board film pressing quality detection and analysis method and system. The method comprises the steps of generating a self-adaptive scanning path based on a design file and surface deformation data; performing multi-modal data acquisition and fusion along a path through optical surface scanning, ultrasonic tomography and an optical coherence tomography imaging assembly; potential defects are positioned, and size, shape, position and defect type probability values are quantized; judging the authenticity of the defect by adopting a three-stage mechanism of cross-modal probability comparison, physical characteristic logic verification and multi-frame time sequence verification; and performing weighted scoring on the real defect matching acceptance standard table, and performing disqualification marking or outputting a process optimization suggestion to the pressing equipment according to a scoring result. According to the invention, the imaging limitation of the transparent coating layer is broken through, the internal interface layering and the precise detection of the microbubbles are realized, and the closed-loop control from detection to production adjustment is formed.

The invention relates to the technical field of foamed silicone rubber surface detection, and discloses a foamed silicone rubber surface detection method based on image visual identification, which comprises the following steps: acquiring a color image of a foamed silicone rubber surface, carrying out graying and normalization processing, and generating a diffuse reflection effective detection area by using a polarization filter difference technology; color abnormity is detected based on an image gridding and gray statistical method, meanwhile, pore and microbubble defects are detected in combination with minimum value seed point extraction and an eight-neighborhood region growing algorithm, finally, various masks are fused, the defect area and number are counted, and a quality inspection report is generated; the method can effectively inhibit highlight interference and accurately identify uneven colors and pore microbubbles, the detection process does not need external training, calculation is efficient, and the method is suitable for rapid detection and quality control of surface defects of foamed silicone rubber.

The invention belongs to the technical field of wastewater treatment, and particularly relates to an efficient ozone micro-nano bubble preparation system and a process method thereof. The device further comprises an ozone preparing unit, a gas conveying pipeline, a jet flow unit, a spiral mixing unit, a Venturi tube, a microporous membrane unit and a reaction unit. The ozone producing unit is connected with the jet flow unit through a gas conveying pipeline, the ozone producing unit comprises an ozone generator, and the gas inlet pressure is regulated and controlled through a gas valve in the gas conveying pipeline; and the jet flow unit is used for generating and conveying a mixed solution with ozone microbubbles. The jet flow unit enables the mixed liquid to form ozone microbubbles based on a Venturi effect and a hydraulic shearing effect; by arranging the jet flow unit, the spiral mixing unit, the Venturi tube and the microporous membrane unit, ozone micro-nano bubbles with high concentration and uniform size distribution can be generated under relatively low energy consumption, so that the treatment efficiency of the ozone micro-nano bubbles in the technical fields of wastewater treatment and environmental protection is improved.

The invention discloses an ultrasonic positioning microscopic imaging method and system based on joint resolution perception and vision Mangbar, and the method specifically comprises the steps: obtaining and preprocessing a plurality of modal angiography data, generating a microbubble motion sequence in combination with blood flow velocity field simulation data, and constructing a data set; inputting the data set into a mixed hierarchical feature pyramid fusion network, carrying out probability density estimation on a microbubble position based on a real-time multi-scale density field estimation algorithm, and introducing a resolution perception algorithm to enhance microbubble features to obtain a plurality of short-track images; performing dynamic feature decoupling and time-frequency analysis on the short-track image, extracting and encoding velocity component features and spatial-temporal context information of a vascular structure, and constructing a double-branch processing network based on visual Mangbar to obtain images respectively reflecting forward motion contribution and backward motion contribution, and finally generating a high-resolution blood vessel image through image fusion. The method has an important value for improving the efficiency and precision in microvascular imaging.

According to the precise diagnosis and treatment integrated platform and method based on the coupling model, the cavitation effect is predicted through numerical simulation, negative feedback adjustment is conducted on microbubble mediated ultrasonic treatment, and precise control over the microbubble mediated ultrasonic treatment is achieved. Acoustic parameters are adjusted in real time, it can be ensured that treatment focuses on a lesion area, damage to surrounding healthy tissue is reduced, and therefore the accuracy and safety of treatment are improved. The platform integrates cavitation detection and an acoustic feedback mechanism, the microbubble cavitation effect can be monitored in real time, and treatment parameters can be automatically adjusted. Negative feedback closed-loop control can ensure a stable cavitation state, tissue damage caused by excessive cavitation is effectively avoided, and the stability and reliability of treatment are improved. The platform simplifies the operation process of controlling acoustic parameters. A doctor can complete the whole process from treatment to monitoring on the same operation interface through the integrated platform, and convenience and efficiency of clinical operation are improved. The platform is not only suitable for tumor treatment, ablation and drug delivery, but also can be applied to multiple treatment fields such as vascular diseases and neuromodulation, and has wide clinical application prospects and market potential.

Systems and methods for applying therapeutic ultrasound to the brain to compensate for attenuation and dephasing of ultrasound by each individual's head. The compensation is based on relative ultrasound through-transmit measurements, which are performed using a set of ultrasonic emitters over one side of the head and a set of receivers on the other side. The measurements are performed with the head absent and present. Based on the difference between these measurements, the set of ultrasound waves is adjusted to compensate for attenuations and dephasing caused by the ultrasound wave passing into the head through the scalp and skull. The adjusted set of ultrasound waves provides intended, deterministic ultrasound intensity at the target location. The deterministic delivery enables safe and effective ultrasonic neuromodulation, local drug release from nanoparticle carriers, and microbubble-based disruption of blood-brain barrier for the delivery of drugs, genes, and stem cells across the blood-brain barrier.

The invention discloses a new medicine application of a local injection acoustic response stent in enhancing ultrasound histotripsy. The acoustic response scaffold (ARS) comprises a scaffold material, fluorocarbon gas or liquid fluorocarbon particles with liquid-vapor phase change capacity, and microbubble cloud in the scaffold generates a strong cavitation ablation treatment effect in a target area under the action of low-frequency and low-sound-pressure ultrasound. Fluorocarbon gas or liquid fluorocarbon particles contained in the ARS form microbubble cloud and ideal cavitation nuclei under low-frequency low-sound-pressure ultrasonic excitation, inertia cavitation resonance is achieved under the ultrasonic action, and then cavitation mechanical damage with local tissue controllable strength is generated. The low-intensity ultrasonic histotripsy has the characteristics of low sound pressure, low sound intensity, high targeting property, small tissue damage outside a target region, simplicity in instrument manufacturing and the like, and the targeting property and the safety of treatment are improved. The method does not need very accurate ultrasonic focusing, reduces the operation difficulty, and has application prospects in multiple medical fields such as prostatic hyperplasia, tumor ablation and tumor immunotherapy.

The invention discloses a method for removing fishy smell of minced fillet and improving gel characteristics based on an electric field effect and application of the method, and relates to the technical field of production of minced fillet products. Comprising the following steps: treating surimi rinsing wastewater by utilizing a low-voltage direct-current electric field to obtain rinsing recovery liquid; rinsing the fresh surimi by using the rinsing recovery liquid, and introducing nitrogen microbubbles in the rinsing process to make full contact with the surimi; and rinsing with clear water, and dehydrating to finish the treatment. According to the method disclosed by the invention, the rinsing recovery liquid treated by the electric field is selected and has a synergistic effect with the introduced nitrogen microbubbles, so that the myofibrillar protein content and the moisture content of the rinsed minced fillet are relatively high, and the fat content and fishy smell substances are obviously reduced; the gel strength of the final gel product reaches 493.03 g.cm and meets the 3A-grade surimi standard (the gel strength is greater than or equal to 400 g.cm), and the quality, color and flavor of the surimi gel are effectively improved; the method is simple to operate, high in efficiency and suitable for industrial production.

The invention relates to a metallized microbubble and a preparation method thereof, a construction method of a multifunctional composite probe, and a rapid bacterium capturing and sterilizing method, and belongs to the technical field of functional material preparation. The method aims at solving the technical problems that in the prior art, a metal coating on the surface of the hollow glass microbubble is not uniform, combination is not firm, and stability is poor. According to the technical scheme, the method is characterized by comprising the following steps: mixing surface-activated hollow glass microbubbles with a polyethyleneimine solution for reaction, and washing and drying to obtain polyethyleneimine-coated hollow glass microbubbles; then reacting with a single-stranded DNA buffer solution to obtain an intermediate product loaded with DNA; then introducing a silver nitrate solution to load silver ions on the surface of the compound; and finally, reducing through a sodium borohydride solution to prepare the metallized microbubbles. The metalized microbubbles prepared by the method can be used for constructing a multifunctional composite probe to realize efficient capture and synergistic antibiosis of targets such as bacteria.

The preparation device comprises a mixing tank, a stirring device and a microbubble generating device are arranged in the mixing tank, the microbubble generating device is composed of a bottom mounting disc and a side wall mounting ring, microbubbles are injected through a first micropore and a second micropore respectively, and the micropores are conical and coated with hydrophobic nano coatings. The pulse airflow device controls airflow through an electromagnetic pulse valve to generate microbubbles. An ultrasonic oscillation device is further arranged at the bottom of the mixing tank, the stirring device comprises a high-shear stirring structure and an auxiliary stirring structure, and the mixing efficiency is enhanced through reverse driving. The preparation method comprises the steps of feeding, micro-bubble injection, gas-liquid synergistic emulsification, gas-liquid auxiliary emulsification and ultrasonic oscillation. Through the synergistic effect of microbubble injection, high shear and ultrasonic oscillation, the mixing uniformity of peanut oil and ingredients is improved, and the mixing time is shortened. The microporous coating and pulse adjustment ensure stable operation of the device, the maintenance period is prolonged to once a month, and the device is suitable for industrial production.

The invention relates to magnetic mineral concentration equipment, and belongs to the technical field of mineral separation, the magnetic mineral concentration equipment comprises a magnetic flotation column cavity, an overflow groove, a stirring device, a feeding device, a magnet exciting coil and a microbubble generating device, and the magnetic flotation column cavity comprises a conical concentration device arranged at the bottom; the overflow groove is formed in the upper part of the magnetic flotation column cavity; the magnet exciting coil is arranged on the periphery of the magnetic flotation column cavity; the microbubble generation device is arranged at the lower part of the magnetic flotation column cavity and / or above the conical concentration device; the feeding device is communicated with the magnetic flotation column cavity and is used for conveying ore pulp to the magnetic flotation column cavity; the microbubble generating device is used for generating bubbles and conveying the bubbles to the magnetic flotation column cavity; the stirring device is arranged in the magnetic flotation column cavity and used for stirring ore pulp; strong magnetic and hydrophilic mineral particles in the stirred ore pulp are discharged through a conical concentration device to become concentrate, and foam formed by weak magnetic or non-magnetic and hydrophobic mineral particles is discharged through an overflow groove to become tailings.

Disclosed herein is a composition for enhanced ultrasound ablation and methods relating to same. The composition may include a microbubble-microdroplet cluster composition, wherein the microbubble-microdroplet cluster composition may include groups of negatively charged microbubbles and positively charged microdroplets permanently held together by their opposing electrostatic attractive forces to form a single, agglomerated entity.

A method for delivering a therapeutic agent to a human brain by delivering systemically a therapeutic agent and applying low intensity pulsed ultrasound (“LIPU”) to the brain in the presence of circulating microbubbles. The therapeutic agent is delivered prior to applying LIPU if it has a plasma half-life of ≥1 h, and the therapeutic agent is delivered after applying LIPU if it has a plasma half-life of <1 h. In a second disclosed method, a first therapeutic agent is delivered systemically, LIPU is applied to the brain in the presence of circulating microbubbles, and a second therapeutic agent is delivered systemically. Also provided is a method for treating a brain disorder in a human by delivering a therapeutic agent systemically, administering a microbubble solution, and applying LIPU to the brain for a period of 1 min. to 30 min.

The invention relates to equipment for synthesizing chlorinated polyvinyl chloride and a synthesis method thereof, and belongs to the technical field of chemical synthesis equipment. Through the synergistic effect of the cavitation effect of ultrasonic waves and the photocatalytic reaction, the ultrasonic waves generate a large number of tiny bubbles in the working solution, on one hand, the tiny bubbles just enable pvc particles with lower density to float and overflow, and photocatalyst particles with higher density are kept at the bottom, so that self-separation of reactants and a catalyst is achieved, and the self-separation effect of the reactants and the photocatalyst is improved. On the other hand, the microbubbles quickly collapse in an extremely short time after floating to the surface of the reaction liquid, a cavitation effect is generated, dispersion of the photocatalyst in the reaction stock solution can be promoted, and the contact opportunity of the photocatalyst and reactants in the reaction stock solution is increased. A local high-temperature and high-pressure environment generated when the microbubbles are broken can enhance the activity of the photocatalytic reaction, and the synergistic effect of the microbubbles and photocatalysis can accelerate the photocatalytic reaction rate, promote the chlorination reaction of chlorine and pvc particles, and improve the chlorination rate.

The invention relates to the technical field of quartz crucibles, and particularly discloses a melting method for reducing microbubbles on the inner surface layer of a quartz crucible. The arc vacuum melting in the melting method disclosed by the invention comprises the following steps of: rising a heat shielding plate to a position which is 350-450mm away from the upper edge of a mold, and melting the inner surface of a crucible for 45-75s by utilizing a high current which is more than 5000A; then moving down the heat shielding plate, keeping the current unchanged, and melting; the heat shielding plate is lifted, the current is adjusted to be 2200-2500 A, and a transparent layer is formed through vacuum melting; stable melting: adjusting the current to be more than 5000A, and performing high-temperature evaporation; then, the current is adjusted to be reduced to 1800-2200 A, and low-temperature melting is conducted for 120-240 s; and repeating stable melting to obtain the quartz crucible to be demoulded. By means of the technical scheme, the number of microbubbles of the prepared quartz crucible is obviously reduced, the compression strength of the crucible is greatly improved, and the service life of the crucible is greatly prolonged.

Provided herein are methods to treat various neurodegenerative disorders comprising delivering a viral particles to the whole brain, including both superficial and deep structures. In some aspects, the viral particles are administered at low dose levels to the CSF, in conjunction with microbubbles followed by application of focused ultrasound (FUS) to a region of interest of the brain, thereby causing entry of the viral particles to the brain.

The present invention provides a microbubble generating device and a microbubble generating method. The microbubble generating device includes a housing with openings at both ends, and at least one shearing assembly is disposed within the housing. The shearing assembly includes a first internal component, a second internal component, and a third internal component, wherein a shearing chamber is formed between the first internal component, the second internal component, and the third internal component. The microbubble generating device provided by the present invention can produce microbubbles with uniform micron and nanometer sizes according to practical production needs, and the microbubbles can exist stably in a liquid phase and are not prone to coalescence. The microbubble generating device also has the advantages of a simple structure, easy disassembly, good sealing, low leakage risk, low energy consumption, low equipment cost, and a small size.

A toilet includes a tank and a bowl. A bubble generation device including a nozzle is configured to release nanobubbles to the tank or the bowl. A controller is configured to generate a command for the bubble generation device to release nanobubbles from the nozzle into the tank and / or the bowl.

According to the chemical material detection method and system based on deep learning provided by the invention, the online adaptive training generative adversarial network BR-GAN is introduced, and the generator can dynamically learn background optical feature mapping under the fine tuning condition of production process parameters; meanwhile, a multi-layer convolution discriminator is used for recognizing time correlation of background optical features, so that a defect-free background reconstruction image matched with the current production condition can be generated, and a difference image is generated by calculating pixel-level residual errors and feature-level attention differences of a real-time image and the reconstruction background; microscopic bubble signals are effectively separated from complex backgrounds changing along with technological parameters, and the effect of accurately detecting microscopic bubbles is achieved.

The invention relates to a physiotherapy bathtub, and belongs to the technical field of bathtubs, the physiotherapy bathtub comprises a bathtub structure, a cover body, a rotation driving mechanism, a hydrotherapy module, a drying module, a phototherapy module and a control module, the control module is in communication connection with the rotation driving mechanism, the hydrotherapy module, the drying module and the phototherapy module, and according to actual physiotherapy requirements, a user can carry out physical therapy on the bathtub. The hydrotherapy module can be started to carry out bubble bath hydrotherapy, or the hydrotherapy module is started to generate microbubbles to carry out massage, the phototherapy module is started to carry out phototherapy, and the drying module can be started to dry the body after the bubble bath is finished. The physiotherapy bathtub provided by the invention integrates the functions of hydrotherapy, drying, phototherapy and the like, has the advantage of rich functions, and meets the requirements of users to the greatest extent.

The invention discloses a flexible ultrasonic wearable device for blood flow velocity detection and thrombolysis treatment. Comprising an FPGA (Field Programmable Gate Array) system control device, a flexible ultrasonic blood flow velocity detection area based on an ultrasonic Doppler principle, a flexible ultrasonic thrombolysis treatment area for emitting low-frequency high-intensity ultrasonic-assisted microbubbles, a double-layer electrode network, a data acquisition card and a signal processing and analyzing module. The blood flow velocity of the human body is detected, the embolism condition of the blood vessel is determined by feeding back blood flow velocity information of multi-point detection, low-frequency high-intensity ultrasonic waves emitted by the flexible ultrasonic thrombolysis treatment area are combined with microbubbles for thrombolysis treatment, the blood flow velocity is monitored in real time in the treatment period, and the equipment safety is improved. The device has the advantages of being portable and wearable, simple to operate and high in signal acquisition precision, monitoring and treatment results of the device can be observed in real time on an upper computer, and the device is convenient to use.

A mixed abrasive synergistic enhancement immersion microjet processing system and method for RB-SiC ceramic microstructures is characterized by: the micro-abrasive air jet nozzle is driven by an active rack and driven gear, and one end is connected to a precision sandblasting machine containing micron-sized abrasive particles; its output end is immersed in a slurry tank containing submicron / nano-sized abrasive particles; the micro-abrasive air jet nozzle ejects a gas-solid two-phase flow and generates a large number of microbubbles; the driving effect of the microbubbles effectively mixes the submicron / nano-sized abrasive particles in the slurry tank with the gas-solid two-phase flow ejected by the micro-abrasive air jet nozzle, thereby obtaining a mixed abrasive synergistic enhancement immersion microjet; the waste liquid passes through a primary filter particle recovery outlet, a secondary filter particle recovery outlet, and a tertiary filter particle recovery outlet in real time, where the micron-sized abrasive particles and erosion debris are screened, dried, and classified for collection, ultimately achieving efficient and high-quality processing of RB-SiC ceramic microstructures.

The invention discloses an oscillation microbubble chip, a separation system and an acoustic manipulation method, the device utilizes the acoustic eddy current effect induced by oscillation microbubbles to realize micro-nano particle acoustic manipulation, the chip structure and operation are simple, the biocompatibility is high, and by designing the chip structure, due to the breathable and water-repellent characteristics of PDMS and the surface tension of fluid, the micro-nano particle acoustic manipulation can be realized. Alternatively arranged equilateral triangle column cavities with different sizes are formed on the side wall of the PDMS microfluidic channel to anchor bubbles. Bubble oscillation is driven by bulk acoustic waves generated by exciting a piezoelectric transducer through a signal generator, symmetrical vortexes are formed on the surfaces of the bubbles through secondary acoustic radiation force generated by bubble oscillation, then large-size particles are captured, and small-size particles flow to an outlet along with flowing under the action of drag force. Gradient separation is adopted to separate small particles from a mixed solution and enrich large particles, enrichment, separation and other control of microparticles are achieved through the acoustic vortex field effect of a specific structure, great potential is achieved in biological research, the structure is simple, the equipment cost is low, and integration is easy.

The utility model provides a cyclone cavitation coupled micro-fine particle mineral flotation device. Comprising a flotation body and a cavitation bubble generator. The flotation body comprises a flotation body cylindrical barrel located on the upper portion and used for raw ore feeding and concentrate collecting, a flotation body conical pipe located on the lower portion and used for separation and tailing discharging, a raw ore feeding pipe arranged at the axis of the flotation body cylindrical barrel, and a pressure stabilizing plate. Hydrodynamic cavitation bubbles generated by a cavitation bubble generator are applied to flotation equipment and are fed into a stirring area of the flotation equipment under pressure, the cavitation bubbles collapse to generate shock waves to clean the surfaces of mineral particles, the effect of dispersing minerals is achieved, special microbubbles are released to form mineralized bubbles with micro-fine particle concentrate, and the mineralized bubbles float upwards; the recovery rate of micro-fine particle minerals difficult to float is remarkably increased, the dosage of reagents is reduced, and efficient flotation is achieved.

The invention provides a method for detecting dissolved gas in transformer oil, and belongs to the technical field of dissolved gas in transformer oil, and the method comprises the following steps: firstly, transmitting a plurality of groups of ultrasonic waves with different frequencies into the transformer oil at the same time, obtaining and preprocessing a joint spectrum, and then utilizing a wavelet multi-scale decomposition technology considering a time sliding window to obtain a pre-processed joint spectrum; the signal is disassembled into a stable spectrum and three levels of fluctuation spectrums. Extracting the characteristics of interference, spectrum attenuation, waveform complexity, coupling, energy distribution and the like from each level of fluctuation spectrum, and calculating the influence characteristics of microbubbles on ultrasonic waves, including acoustic attenuation, propagation velocity, scattering, acoustic impedance change and nonlinear acoustic characteristics. By performing weight fusion on the three-level fluctuation spectrum energy ratio, comprehensive characteristics are generated and input into a gas calculation model, so that the state of gas in transformer oil is accurately evaluated and diagnosed, and the technical problem that an existing offline sampling analysis method is difficult to meet the requirement of a power system for evaluating the running state of a transformer in real time is solved.

The invention discloses a sealing ring processing quality monitoring system, and relates to the technical field of sealing ring processing monitoring. The system comprises a polarization-dark field composite imaging module which is used for obtaining a target image which eliminates specular reflection and highlights scattering characteristics of tiny bubbles through the synergistic effect of polarization filtering and annular dark field illumination; the microbubble feature enhancement module is used for carrying out feature extraction and enhancement on the target image by adopting a deep learning network comprising a multi-scale cavity convolution unit and a self-adaptive attention mechanism unit; and the self-adaptive threshold segmentation module is used for processing the enhanced image in combination with segmentation strategies of the dual-threshold screening unit and the attention map guide segmentation unit so as to accurately segment a micro bubble region. Through cooperation of polarization-dark field composite imaging, a microbubble feature enhancement network and adaptive threshold segmentation, high-precision rapid detection of the microbubbles on the surface of the transparent silica gel sealing ring is realized.

The invention discloses a cardiovascular disease detection method based on image analysis, and particularly relates to the technical field of cardiovascular disease detection. Whether further detection is needed or not is judged by evaluating the distribution uniformity of microbubbles at the vascular branches and the development degree of myocardial tissue lesions. If further detection is needed, the photoacoustic imaging technology is adopted, the saturation degree of photoacoustic signals is analyzed, and a nonlinear signal demodulation algorithm is combined, so that the detection accuracy of the tiny calcification in the cardiovascular system is evaluated. By analyzing the influence of the cardiovascular tissue fiber arrangement direction on the optical signal propagation path, the abnormal degree of the lesion area fiber structure is evaluated. The cardiac muscle tissue lesion degree, the micro calcification detection accuracy and the abnormal degree of the fiber structure are comprehensively analyzed, the severity of the cardiovascular disease is evaluated, whether clinical intervention measures are needed or not is judged, early diagnosis and accurate evaluation of the cardiovascular disease are achieved, and the diagnosis efficiency and accuracy are improved.

An ultrasound transducer ultrasonically processes a target volume by emitting a sequence of acoustic pulses to the target volume to alter tissue properties while at least one acoustic detector detects an ultrasound reflected signal from the target volume after each acoustic pulse, and a controller (i) estimates an activity of the contrast agent at the target volume based on a comparison between values of signal parameters in the reflected signal following successive acoustic pulses, and (ii) controls the ultrasound transducer to alter the tissue property based on the estimated activity.

According to the multifunctional heart color ultrasound acoustic contrast examination device, the stirring mechanism is arranged in the cylinder, and the sealing mechanism and the mixing mechanism are integrated on the stirring mechanism, so that the efficiency and the sealing reliability in the contrast agent stirring process are remarkably improved. Wherein the mixing mechanism is fixedly connected to the outer wall of the stirring shaft and can drive the stirring plate to efficiently stir in multiple directions when the stirring shaft rotates, so that a contrast agent and gas can be fully mixed to generate mixed liquid with uniform and stable microbubbles, and the imaging quality and diagnosis accuracy of heart color ultrasound acoustic contrast examination are improved.

The invention discloses a residual oil hydrogenation microbubble generating device, which is arranged at the front end of a residual oil hydrogenation fixed bed reactor, is used for pretreating a gas-liquid two-phase material, and comprises a first crushing assembly which is arranged in a tank body of a generating tank, is positioned at the lower part of the tank body and is provided with rotary crushing cutters which are arranged in a layered manner; the rotary crushing cutter is driven by a driving unit, rotates along a vertical rotating shaft and is used for crushing large bubbles into small bubbles; and the second crushing assembly is arranged in the tank body of the generation tank and located above the first crushing assembly, the second crushing assembly is provided with a horizontally-arranged filtering and crushing plate, and the filtering and crushing plate can be driven by the same motor in the driving unit to reciprocate in the vertical direction and is used for crushing the small bubbles into microbubbles. According to the invention, large bubbles in residual oil can be broken into small bubbles, so that the mass transfer and reaction efficiency of gas and liquid phases in a residual oil hydrogenation system is effectively improved.