23 results about "Hyperthermia Treatment" patented technology

includes an implantable intravesical floating hyperthermia device and an external pulse heating apparatus. The floating device includes a sealed non-metallic housing, a metal coil configured to inductively couple with an alternating magnetic field generated outside the human body to generate heat for tumor hyperthermia, a temperature sensor, a wireless transmission module, and a power supply module. The pulse heating apparatus includes at least one magnetic field generation module and a control module that controls the heating temperature according to the temperature signal from the floating device. The system supports multiple, timed, and temperature-controlled hyperthermia sessions with a single transurethral insertion, reducing patient trauma and enabling outpatient self-management.

A single-cell transcriptome-guided multimodal synergistic injectable magnetically responsive biomimetic hydrogel system, its preparation method, and its application are described. This hydrogel platform is a three-level composite system of "matrix-microsphere-nanoparticle": the primary structure is a photocrosslinked methacryloyl hyaluronic acid three-dimensional network matrix; the secondary structure is GelMA microspheres loaded with MTPT nanoparticles prepared by microfluidic control; and the tertiary structure consists of bevacizumab and magnetite nanoparticles dispersed in the HAMA matrix. The MTPT nanoparticles have a mesoporous silica core, which is sequentially coated with temozolomide, a polydopamine coating, and a T7 targeting peptide. Under the activation of an alternating magnetic field, Fe3O4 generates a magnetothermal effect, which not only achieves local hyperthermia but also accelerates the time-sequential release of bevacizumab and MTPT, synergistically exerting the effects of chemotherapy, anti-angiogenic therapy, and hyperthermia.

This invention discloses a method for assessing hypoxia response based on dynamic evaluation of heart rate deceleration force and HRV, belonging to the field of biomedical signal processing. The method simultaneously acquires electrocardiogram (ECG) signals and environmental and blood oxygen parameters to dynamically correct the risk baseline; extracts frequency domain, time domain, and heart rate deceleration force features from the ECG signals and establishes a dual-channel cross-judgment logic; inputs the judgment results with the current blood oxygen saturation into a lightweight neural network inference output risk stratification; controls a wearable actuator to initiate multi-target stratified sequential stimulation including heat and vibration based on the stratification results, and adaptively updates the individualized hyperthermia prescription based on the intervention efficacy index, ultimately achieving dual-channel synergistic control of oxygen therapy and hyperthermia. This invention effectively solves the shortcomings of traditional methods, such as delayed early warning and inability to dynamically correct in non-networked environments, constructing a closed loop from precise monitoring to multi-target synergistic intervention, significantly improving the body's adaptability and resilience to hypoxia.

A new generation of precision medicine with interfaces processing the predictive feedback over the course of hyperthermia treatment sessions is provided. Implementation of MR-thermometry measurements and real-time spatial imaging can resolve many of the limiting factors currently associated with hyperthermia treatment. More significantly, implementation of artificial intelligence (machine learning) mediated image analysis and database construction can provide the international community with standards for monitoring, and thermal dose calibration.

A folded dipole patch antenna for use in a hyperthermia applicator is described. The antenna includes a dielectric circuit board, and a folded dipole microstrip antenna. The dielectric circuit board has a top side and a bottom side. The folded dipole microstrip antenna is formed on the top side and includes two meander paths mirror each other. A pair of parallel metallic strips is located on the bottom side. A coaxial feed port is connected to the pair of parallel metallic strips. The antenna is configured to resonate in a frequency range of about 434 MHz upon application of an input signal at the coaxial feed port. The folded dipole patch antenna has a small size and does not require an impedance matching circuit. The hyperthermia applicator is configured to emit microwave energy toward a target tissue within a human body.

This application provides a laser hyperthermia device and a laser hyperthermia method. The laser hyperthermia device includes an ablation component and a laser probe. The ablation component emits laser light to ablate target tissue. The proximal end of the laser probe is connected to the optical path of the ablation component to conduct the laser light to the target tissue area. The laser probe includes a stator assembly and a rotor assembly arranged axially toward the distal end. The stator assembly is used to adjust at least one of the laser beam diameter, beam focal length, and light intensity. The rotor assembly is configured to rotate in a radial plane with the axial direction as the central axis to adjust the laser emission direction. The embodiments of this application enable more concentrated laser energy, thereby improving the accuracy of laser ablation, reducing energy requirements, and thus reducing ablation costs. During the rotation of the rotor assembly, the laser light is emitted toward the area of ​​the target tissue that needs ablation. Multiple ablations of the same target tissue can reduce the risk of infection of the ablation site and improve ablation efficiency.

The application relates to the technical field of tumor hyperthermia, in particular to a temperature field acquisition method and device for tumor thermal ablation surgery, wherein the method comprises the following steps: segmenting a three-dimensional tumor model from a three-dimensional magnetic resonance image in a target liver; calculating the centroid position of the three-dimensional tumor according to the three-dimensional tumor, and solving the ellipsoid parameters of the three-dimensional tumor; querying a preset database by using the ellipsoid parameters to obtain the closest ellipsoid data, and acquiring the current temperature field distribution from the closest ellipsoid data. Therefore, the problems in the prior art that the finite element calculation is huge in amount, time-consuming, and the temperature field cannot be acquired and monitored in real time, the accuracy and real-time performance of the surgery are reduced, and the requirements of the tumor thermal ablation surgery cannot be met are solved.

Apparatus for delivering in vivo hyperthermia treatments to a subject and methods of performing such treatments are provided. The apparatus comprises an imaging device, such as an MRI scanner, a microwave applicator, and a controller to target particular tissues within the subjects body for hyperthermia treatment. The microwave applicator emits microwave energy toward the target tissue and the imaging device provides real-time feedback as to the position of the applicator relative to the target tissues and thermometry data so as to permit real-time adjustment of the applicators operating parameters.

A massage ball vertically-moving mechanism for a hyperthermo-therapeutic apparatus, includes a hyperthermo-therapeutic massage ball; a ball support, and configured to support the hyperthermo-therapeutic massage ball and configured to vertically move; and a driving gear installed at the movable frame and configured to vertically move the ball support. A rack gear meshing with the driving gear is integrally formed with the ball support. A movable wheel is installed at the rack gear, wherein a vertical-movement guide is fixedly installed at the movable frame. A curved wheel guide groove for guiding the movable wheel during the vertical movement of the ball support is defined in the vertical-movement guide. A guide wheel is installed on one side of the vertical-movement guide so as to guide a vertical movement of the rack gear.

In one embodiment, a method includes positioning an infrared hyperthermia heating device at least a predetermined distance away from an area of a patient's skin treated with radiation therapy and activating the infrared hyperthermia heating device to heat the area of the patient's skin. The method further includes heating, by the infrared hyperthermia heating device, the area of the patient's skin to a predetermined temperature; maintaining, using the infrared hyperthermia heating device, the predetermined temperature for a predetermined period of time; and deactivating the infrared hyperthermia heating device after the predetermined period of time to cease heating the area of the patient's skin.

This invention provides a modular wristband device with thermotherapy function, belonging to the field of physiotherapy device technology. It includes a wristband, a main controller, a fixed shell, a heat-conducting medium layer, a thermotherapy module, a snap-fit ​​assembly, a one-way locking mechanism, a contact part, and a safety connection module. The thermotherapy module is one of far-infrared heat therapy, moxibustion, or medium-based heat transfer modules, which users can select as needed. The connection to the fixed shell is achieved through an innovative snap-fit ​​assembly and one-way locking mechanism. A rotating shaft drives multiple cams to rotate, switching the connection state from elastic snap-fit ​​to mechanical locking. Only after complete locking is the power supply and communication line between the micro-control unit inside the module shell and the main controller connected, forming a safety logic of structural locking followed by electrical connection. This achieves a unified approach of safety interlocking, functional modularity, and intelligent control, significantly improving the safety, convenience, and efficacy of home thermotherapy devices.

This invention belongs to the fields of biomedical engineering and nanomaterials technology, and provides a drug-loadable sodium alginate / citric acid embolization microsphere with photothermal effects, its preparation method, and the drug-loaded microspheres. The invention utilizes electrostatic spraying technology to prepare drug-loadable black phosphorus nanosheets (BPNS) of sodium alginate (ALG) / sodium citrate (SC) embolization microspheres. These microspheres are then mineralized to obtain the photothermal drug-loadable sodium alginate / citric acid embolization microspheres. In vitro mineralization enhances the surface roughness of the microspheres, achieving integration of coagulation, embolization therapy, photothermal therapy, and chemotherapy. The microspheres are uniform in size, controllable, and well-dispersible, exhibiting good coagulation effects. They can be used for embolization, local chemotherapy, and local hyperthermia to achieve effective tumor treatment. The process is simple and easy to manufacture. The product exhibits good dispersibility and excellent sphericity, with a diameter between 200-300 μm. It can be used for interventional treatment of solid tumors such as liver cancer.

The present application belongs to the technical field of medical devices, and specifically relates to a microwave thermotherapy device suitable for acupuncture, aiming to solve the problem of lack of special safety protection for microwave thermotherapy after acupuncture. The device comprises a microwave thermotherapy module, a metal detection module, a control module, a position confirmation module, a prompt module, a support module and a driving module; the position confirmation module comprises double detection units, which are matched with light supplementing and distance measuring components to realize consistency confirmation of detection and thermotherapy areas and real-time displacement monitoring. The metal detection module checks the metal of the affected area, the control module links all the modules, and the microwave thermotherapy module is prohibited from working when the metal detection is unqualified or the position deviation occurs, and the prompt module gives a prompt. The device has reasonable structure, convenient operation and accurate detection, can effectively avoid the risk of burns caused by metal residues, is suitable for the clinical scene of microwave thermotherapy after acupuncture, and provides reliable support for clinical treatment.

The application relates to the technical field of head hyperthermia instruments, in particular to a head hyperthermia instrument convenient to adjust, which comprises a host computer and a head heating cover body, the host computer is connected with the head heating cover body through wired or wireless control connection, the head heating cover body comprises an outer shell and an inner shell, and the inner wall of the inner shell is uniformly provided with multiple groups of medicine turning units; the inner shell is composed of a middle shell and side shell bodies on two sides, and a telescopic assembly is arranged between the middle shell, the side shell bodies and the outer shell, the head hyperthermia instrument is provided with a gas guide pipe, a piston plate, a movable rod, a sliding block, a sliding groove, a movable plate, multiple cylindrical air bags, a heating element, an electric telescopic rod, a guide assembly and a pressure sensor, the host computer gas path and the regulation and control function are combined, the turning and flexible extrusion and mixing of the head medicine are realized, the penetration and absorption of the medicine are assisted by moderate warm heating, the inner shell spacing can be adjusted to adapt to different head profiles, and the treatment safety is ensured through pressure detection and regulation and control.

A hyperthermia implant 20 for hyperthermia treatment of tissue 30 of a human or animal body. The implant comprises at least one piece of a large Barkhausen jump material (LBJ) and a magnetic field may be applied to the implant to heat the surrounding tissue. The implant may also be deployed to mark a tissue site in the body for subsequent surgery, thereby providing a combined system for locating an implant and treating the surrounding area. The system includes a handheld probe 14 to excite the implant below the switching field for bistable switching causing a harmonic response to be generated in a sub-bistable mode that allows the implant to be detected and localised.

The application discloses a kind of intelligent whole-body heat treatment spectrum therapy systems, comprising: treatment cabin body, the middle part of the treatment cabin body is set as the spectrum therapy cavity for human body to enter;With the treatment bed of the spectrum therapy cavity cooperation;Spectrum irradiation device is set in the spectrum therapy cavity;With human body connection cooperation human body parameter monitoring device;With infrared thermal imaging scanning device for human body thermal imaging scanning;Temperature detection device is set in the treatment cabin body;Power module is powered for each device;With the control device of the spectrum irradiation device, human body parameter monitoring module, infrared thermal imaging scanning device, temperature detection device connection;The control device is according to the data parameter that human body parameter monitoring device, infrared thermal imaging scanning device, temperature detection device feedback, adjusts the irradiation intensity of the spectrum irradiation device.The application can irradiate the whole body of human body and the treatment process is realized intelligent control by control device.

The utility model discloses a kind of radiotherapy thermotherapy collaborative devices based on focus precision positioning, it is related to focus positioning technical field, including radiotherapy thermotherapy collaborative device ontology, the side of radiotherapy thermotherapy collaborative device ontology is movably connected with mobile station, and the inside of radiotherapy thermotherapy collaborative device ontology is provided with laser emitter;Sunshade module, the sunshade module is located at the both sides of radiotherapy thermotherapy collaborative device ontology, and sunshade module includes elastic member.The utility model can shield external light when carrying out focus detection to patient, avoid light strong ghosting influence detection effect generated on the surface of patient's body, to affect the detection accuracy of CT detector, reduce the error occurrence rate of diagnosis, influence the best treatment opportunity of patient, while after detection is completed, device utilizes the synergistic effect of positioning plate and marker pen in positioning module, automatically position marks to patient focus site, without manual marking of medical staff, reduce the effect of its operation step.

The present application relates to the technical field of experimental animal hyperthermia, and discloses a microwave hyperthermia target area temperature constant control and regulation system for experimental animals. The signal response module of the system responds to a microwave hyperthermia control signal; the temperature data acquisition module acquires temperature data of multiple preset positions in the target area in real time; the initial state determination module determines the starting temperature of the target area based on the temperature data; the threshold comparison module compares the residual temperature difference corresponding to the starting temperature with a preset threshold; when the residual temperature difference is less than or equal to the preset threshold, the first control execution module controls the output power of the microwave emitter by using a first control strategy; when the residual temperature difference is greater than the preset threshold, the second control execution module divides the hyperthermia process into multiple time windows and applies different control strategies. The system can improve the temperature control precision and stability of the target area and meet the experimental requirements.

This invention belongs to the field of hyperthermia equipment control technology, and particularly relates to a deep-conversion phased array focused tumor hyperthermia method and system. During the radio frequency emission pause, backscattered signals containing tissue dielectric mutation characteristics are acquired. A coherent crosstalk assessment matrix is ​​constructed, and a residual compensation phase sequence is extracted to reshape the coherent superposition of the beam in the target area. The deviation between the planned and actual temperature rise rate in the target area is converted into a global power boost compensation coefficient through nonlinear logarithmic mapping to smoothly compensate for energy drops. The standing wave ratio (VSWR) of each channel is monitored in real time, and a piecewise exponential penalty mechanism is used to calculate the safety tolerance factor. The power reduced from high-risk channels is weighted and allocated to safe channels to maintain a constant total energy flux. This invention improves the focus accuracy in heterogeneous target areas, effectively suppresses thermodynamic oscillations, and safely avoids the risk of hardware power amplifier damage.

The application discloses a flexible driving hand function rehabilitation device combining heat therapy and water exercise therapy, which comprises an exoskeleton rehabilitation glove, a temperature detection module and a water tank, the exoskeleton rehabilitation glove comprises a glove body and flexible driving modules arranged at corresponding positions of five fingers respectively, the flexible driving module is a laminated flexible sheet structure, and comprises a first connecting layer, a transmission layer, a second connecting layer and a driving layer in sequence from the side close to the finger to the side away from the finger, the temperature detection module is arranged in the water tank, and the water tank is used for containing hot water and cooperating with the temperature detection module to monitor the water temperature in real time, so that heat therapy and water exercise training are realized synchronously. The flexible driving module is adopted to drive, the structure is simple, light, soft, the functions of heat therapy, driving and training are fused, and a safe, effective and easy-to-implement rehabilitation scheme is provided for a stroke hand function disorder patient.

The application discloses a variable frequency radiator array structure. The device comprises a plurality of low-frequency dipole antenna units with a working frequency lower than 433 MHz, which are arranged along an elliptical or quasi-elliptical track to form a radiator array. By independently regulating the amplitude (or power) and phase of the input signals of each antenna unit, the electromagnetic energy generated by the radiator array can be focused in a predetermined target area of deep tissues of a human body, and the size of the focus spot can be regulated by regulating the working frequency. A water bag filled with deionized water is installed on the inner side of the device, and the energy penetration efficiency of the array radiator is improved through impedance matching, while the body surface temperature is kept constant to prevent high-heat burns. The system can realize non-invasive and tunable deep targeted heating, and is suitable for medical fields such as tumor hyperthermia, and has the advantages of large penetration depth, accurate focusing and high safety.

This invention discloses a non-destructive temperature measurement method based on the sound absorption coefficient. It involves using an ultrasonic probe to emit ultrasonic pulses that strike a sample through a medium (pure water) at different temperatures, generating echoes. The relationship between acoustic parameters such as sound velocity and echo energy and temperature is determined by analyzing the time-shift and amplitude changes of the echoes at different temperatures. The sound absorption coefficient is inversely proportional to the cube of the sound velocity and the echo amplitude. The sound absorption coefficient is calculated using a formula, and its correlation curve with temperature is fitted. This curve is then compared with the correlation curve of measured echo energy versus temperature for verification. This method offers higher accuracy and is more suitable for non-invasive temperature measurement in tumor hyperthermia.