838results about How to "Short maintenance period" patented technology

Disclosed are devices and methods for detecting, preventing, and/or treating neurological disorders. These devices and methods utilize electrical stimulation, and comprise a unique concentric ring electrode component. The disclosed methods involve the positioning of multiple electrodes on the scalp of a mammal; monitoring the mammal's brain electrical patterns to identify the onset of a neurological event; identifying the location of the brain electrical patterns indicative of neurological event; and applying transcutaneous or transcranial electrical stimulation to the location of the neurological event to beneficially modify brain electrical patterns. The disclosed methods may be useful in the detection, prevention, and/or treatment of a variety of indications, such as epilepsy, Parkinson's Disease, Huntington's disease, Alzheimer's disease, depression, bipolar disorder, phobia, schizophrenia, multiple personality disorder, migraine or headache, concussion, attention deficit hyperactivity disorder, eating disorder, substance abuse, and anxiety. The disclosed methods may also be used in combination with other peripheral stimulation techniques.

A method for the detection of analytes using resonant mass sensors or sensor arrays comprises frequency encoding each sensor element, acquiring a time-domain resonance signal from the sensor or sensor array as it is exposed to analyte, detecting change in the frequency or resonant properties of each sensor element using a Fourier transform or other spectral analysis method, and classifying, identifying, and/or quantifying analyte using an appropriate data analysis procedure. Frequency encoded sensors or sensor arrays comprise sensor elements with frequency domain resonance signals that can be uniquely identified under a defined range of operating conditions. Frequency encoding can be realized either by fabricating individual sensor elements with unique resonant frequencies or by tuning or modifying identical resonant devices to unique frequencies by adding or removing mass from individual sensor elements. The array of sensor elements comprises multiple resonant structures that may have identical or unique sensing layers. The sensing layers influence the sensor elements' response to analyte. Time-domain signal is acquired, typically in a single data acquisition channel, and typically using either (1) a pulsed excitation followed by acquisition of the free oscillatory decay of the entire array or (2) a rapid scan acquisition of signal from the entire array in a direct or heterodyne configuration. Spectrum analysis of the time domain data is typically accomplished with Fourier transform analysis. The methods and sensor arrays of the invention enable rapid and sensitive analyte detection, classification and/or identification of complex mixtures and unknown compounds, and quantification of known analytes, using sensor element design and signal detection hardware that are robust, simple and low cost.

Disclosed herein is a system for rapidly resolving position with centimeter-level accuracy for a mobile or stationary receiver [4]. This is achieved by estimating a set of parameters that are related to the integer cycle ambiguities which arise in tracking the carrier phase of satellite downlinks [5,6]. In the preferred embodiment, the technique involves a navigation receiver [4] simultaneously tracking transmissions [6] from Low Earth Orbit Satellites (LEOS) [2] together with transmissions [5] from GPS navigation satellites [1]. The rapid change in the line-of-sight vectors from the receiver [4] to the LEO signal sources [2], due to the orbital motion of the LEOS, enables the resolution with integrity of the integer cycle ambiguities of the GPS signals [5] as well as parameters related to the integer cycle ambiguity on the LEOS signals [6]. These parameters, once identified, enable real-time centimeter-level positioning of the receiver [4]. In order to achieve high-precision position estimates without the use of specialized electronics such as atomic clocks, the technique accounts for instabilities in the crystal oscillators driving the satellite transmitters, as well as those in the reference [3] and user [4] receivers. In addition, the algorithm accommodates as well as to LEOS that receive signals from ground-based transmitters, then re-transmit frequency-converted signals to the ground.

Disclosed are therapeutic methods for the treatment of disease material involving administration of a thermotherapeutic magnetic composition, which contains single-domain magnetic particles attached to a target-specific ligand, to a patient and application of an alternating magnetic field to inductively heat the thermotherapeutic magnetic composition. Also disclosed are methods of administering the thermotherapeutic magnetic material composition. The thermotherapeutic methods may be used where the predetermined target is associated with diseases, such as cancer, diseases of the immune system, and pathogen-borne diseases, and undesirable targets, such as toxins, reactions associated with organ transplants, hormone-related diseases, and non-cancerous diseased cells or tissue.

The present invention discloses the present invention discloses a power toothbrush that includes a body portion 105. An elongated level arm 102 extends from one end of the body portion to a toothbrush head 101 disposed at a distal end of the toothbrush. The toothbrush head includes a plurality of brush bristles. The elongated lever arm 102 is mounted on a vibrating pivot 104 driven by rotational DC motor engaging and pushing a set of permanent magnets attached to a two-arm fork rotating along the lever arm 102. In a preferred embodiment, the DC motor drives a three-leg permanent magnets each disposed at a 120-degree phase from each other for driving the two-arm fork for generating a vibration that three-times the frequency of the DC motor's rotational frequency.

Disclosed are compositions comprising magnetic nanoparticles, a biocompatible coating, and a target-specific ligand. Also disclosed are devices for treating diseased tissue for use with such compositions. Further disclosed are methods for treating diseased tissue, such as cancer, using such compositions and devices, as well as methods for treating diseased tissue utilizing hypertermia.

A charged particle optical system comprising a beamlet generator for generating a plurality of beamlets of charged particles and an electrostatic deflector for deflecting the beamlets. The electrostatic deflector comprises first and second electrodes adapted for connection to a voltage for generating an electric field between the electrodes for deflection of the beamlets, the electrodes being at least partially freestanding in an active area of the electrostatic deflector. The electrodes define at least one passing window for passage of at least a portion of the beamlets between the electrodes, the passing window having a length in a first direction and a width in a transverse direction. The system is adapted to arrange the beamlets in at least one row and to direct a single row of the beamlets through the passing window of the electrostatic deflector, the beamlets of the row extending in the first direction. A substantial part of the electrostatic deflector extends beyond the passing window in the first direction.

An audio encoder adapted for encoding frames of a sampled audio signal to obtain encoded frames, wherein a frame has a number of time domain audio samples, having a predictive coding analysis stage for determining information on coefficients of a synthesis filter and information on a prediction domain frame based on a frame of audio samples. The audio encoder further has a frequency domain transformer for transforming a frame of audio samples to the frequency domain to obtain a frame spectrum and an encoding domain decider for deciding whether encoded data for a frame is based on the information on the coefficients and on the information on the prediction domain frame, or based on the frame spectrum. Moreover, the audio encoder has a controller for determining an information on a switching coefficient when the encoding domain decider decides that encoded data of a current frame is based on the information on the coefficients and the information on the prediction domain frame when encoded data of a previous frame was encoded based on a previous frame spectrum and a redundancy reducing encoder for encoding the information on the prediction domain frame, the information on the coefficients, the information on the switching coefficient and/or the frame spectrum.

An apparatus for conducting aqueous liquid media includes a plurality of static mixers, a gas distributor assembly with a plurality of nozzles, at least one impeller having blades attached thereto and a plurality of static mixer assemblies having flow guide elbows and collectors. The static mixer assemblies are independently and separately mounted to orient to the current leaving the blade tips of the impeller. Swirlers are also described as being utilized in place of the static mixers.

The present invention relates to seven isolated breast cancer-associated (BCA) polynucleotides, polypeptides, and variants thereof. The invention also relates to BCA antagonists. The invention also encompasses pharmaceutical compositions comprising BCA polynucleotides, BCA polypeptides, or BCA antagonists. The invention also contemplates methods for preventing or treating cancer, particularly breast cancer, comprising administering to a patient in need of such treatment a composition comprising a BCA polynucleotide, polypeptide, antagonist, or variant thereof. The invention also relates to methods for diagnosing, staging or determining a prognosis of a BCA-related disorder.

A data processing apparatus has a data saving control portion. At shutdown, within the period after a fall in the source voltage is detected until the source voltage falls down to the lower limit at which the apparatus is guaranteed to operate, the data saving control portion saves to a non-volatile memory all the data needed to restore the state of an electronic circuit portion.

A supercharged internal combustion engine system wherein the supercharger assembly includes an ejector pump driven by high-pressure air for pumping intake air into engine combustion chamber. The ejector pump uses a supersonic driving nozzle and a diffuser, each of which can be provided either with a fixed throat area or with a variable throat area. The system includes means for sensing engine power demand and controlling the supercharging action. Effective supercharging with fast response to demand is achieved even at low engine speeds. During periods of natural engine aspiration the ejector pump can be by-passed to reduce flow impedance. The invention permits increasing power output from small displacement engines. As a result, acceleration and grade ascent capabilities of automotive vehicles with small displacement engines having good fuel economy is improved. The system can be also operated to reduce engine exhaust emissions during cold start.

Disclosed are devices for targeted delivery of thermotherapy. These devices are useful in the treatment of diseased tissue in conjunction with magnetic compositions. Further disclosed are methods for treating diseased tissue, which involve the administration of a thermotherapeutic magnetic composition to a patient or a portion of a patient, and the application of an alternating magnetic field to inductively heat the thermotherapeutic magnetic composition. The devices and the methods disclosed herein are useful for the treatment of a variety of indications, such as cancer, diseases of the immune system, pathogen-borne diseases, hormone-related diseases, non-cancerous diseased cells or tissue, and undesirable matter, such as toxins and reaction-by-products associated with organ transplants.

In a liquid crystal display device of the in-plane switching mode (IPS mode), the potential of data that is output from a data driver is set at values between potentials that are given to common lines. Two levels, i.e., high and low levels, are prepared for the potential to be given to the common lines and the potential is inverted between those levels in every field, whereby the polarity of a voltage between both electrodes of a pixel is inverted. As a result, the potential variation ranges of signals that are output from the data driver and a scan driver can be greatly reduced from those of the conventional case, which contributes to reduction in the power consumption of the drivers. Since the voltage applied to a switching element for controlling each pixel can be reduced, the load of the switching element can also be reduced.