I have discovered cosmetic mask compositions suitable for face, neck, chin or body applications. These compositions synergistically combine at least one skin beneficial cosmetic or drug composition with at least one composition to promote excess fat reduction, cellulite control, or muscle toning benefits. The mask composition also contains at least one binder composition that binds with other beneficial ingredients by electrostatic, atomic, or ionic charges to synergistically enhance their topical site-specific benefits. These mask compositions are suitable for a variety of delivery system methods that include peel-off mask, leave-in mask, moisturizing mask, exfoliating mask, prosthetic mask, soaking mask, depilatory mask, foaming mask, rinse-off mask, sloughing mask, rub-off mask, two-phase mask, dual-chamber mask, and self-heating (heat releasing) mask.