93 results about "Fallopian tube" patented technology

The present application discloses a gene point mutation mouse model construction method, comprising: by taking T274M mutation on Kcnq2 Exon6 as a target, designing sgRNA and ssODN; selecting a female mouse of a set week age as an ovum donor, injecting a certain dose of serum gonadotropin and human chorionic gonadotropin into the abdominal cavity of the female mouse, then mating the female mouse with a mating male mouse, and collecting zygotes of the mated female mouse; injecting Cas9 protein, ssODN and sgRNA into the pronuclei of the zygotes by means of a microinjection technique, transplanting the zygotes obtained after injection into the ampulla of the fallopian tube of a surrogate female mouse, and obtaining a neonatal mouse after the pregnant female mouse gives birth; respectively designing a pair of identification primers F1, R1 at two ends of a mutation site on the basis of a Kcnq2 gene point mutation site, identifying the neonatal mouse, and screening out a Kcnq2T274M / + point mutant mouse in which T274M mutation is successfully knocked.

The utility model relates to the technical field of fallopian tube dredging devices, in particular to a fallopian tube catheter suite, a guide tube comprises a first tube body and a first connector which are communicated, the first tube body can be inserted into an outer sleeve, and an inner catheter can be inserted into the first tube body from a side connector; the fallopian tube suite can be switched to a first working state when the guide tube is located in the outer sleeve; on the basis of the first working state, when the inner guide pipe is located in the guide pipe, the inner guide pipe can be switched to the second working state; on the basis of the second working state, the guide wire can be switched to the third working state when the guide wire is located in the inner catheter; the fallopian tube catheter suite has the advantages that the fallopian tube catheter suite provides a hardware basis for a series of operations such as fallopian tube radiography, sterilization, dredging, suction and lavage, the functions can be achieved through one suite, and the surgical operation process is greatly simplified.

The invention pertains to a foamable, echolucent composition, wherein the composition comprises (i) a gelling agent, (ii) water, and (iii) between 0.005 and 20 vol.% oil based on total volume of the composition, wherein the composition turns echogenic when foamed, and preferably has a viscosity of at least 1500 cP. Also, the invention pertains to a foamed, echogenic, image-enhancing composition, wherein the composition comprises (i) a gelling agent, (ii) water, (iii) between 0.005 and 20 vol.% oil based on total volume of the composition, and (iv) air or gas bubbles, wherein the composition preferably has a viscosity of less than 1500 cP, most preferably 50 – 500 cP.

The invention relates to a cherry valley duck PLV virus vaccine as well as a preparation method and application thereof, and belongs to the technical field of virus immunity. The vaccine is prepared by taking a Parry's Lagon virus (PLV) virus strain PLV-20155 as an immunogen, the strain is preserved in the China General Microbiological Culture Collection Center (CGMCC), and the preservation number is CGMCC NO.46296. The invention further discloses a preparation method of the vaccine. The vaccine is a PLV-20155 virus inactivated vaccine, and the preparation method of the vaccine comprises the following steps: inoculating the PLV-20155 virus into an SPF chick embryo for propagation, harvesting a virus liquid, inactivating with formaldehyde, verifying safety, emulsifying with white oil to prepare the vaccine and the like. In addition, the vaccine disclosed by the invention can be used for effectively preventing diseases such as laying rate reduction, follicle necrosis and fallopian tube atrophy of the cherry valley ducks caused by the PLV-20155 virus, and the economic benefit of breeding is remarkably improved.

Systems, methods and devices for endoluminal surgical procedures include a robotic surgical systems adapted and configured to perform lower and upper gastrointestinal endoluminal submucosal dissection (ESD), endoluminal ‎sleeve gastroplasty (ESG), trans-oral endoluminal fundoplication, bariatric endoluminal antral myotomy (BEAM), peroral endoluminal myotomy (POEM), gastroplasty with endoscopic myotomy (GEM), trans-vaginal hysterectomy, trans-vaginal oophorectomy, and trans-vaginal oophoro-salpingectomy. The systems include a physician console, a patient cart and a system controller. The system controller is adapted and configured to receive a plurality of control inputs from ‎each of a plurality of hand control input devices, to process the plurality of control inputs and to ‎transmit a plurality of control outputs to an axial translation actuator, a roll actuator, ‎a steerable overtube controller, a plurality of instrument controllers and a videoscope ‎controller.

The invention discloses a free directional guide visual guide wire mirror device. The device mainly comprises a handheld handle, an imaging optical fiber, an illumination optical fiber, a miniature view finding objective lens group, a photoelectric conversion image acquisition group, a flexible outer sleeve and a front-end free directional guide end, and the outer diameter of the device is smaller than 0.9 mm. And through a unique free directional guiding function, the visual probe can enter a superfine lumen and a narrow part for visual exploration on the premise of not damaging the mucous membrane of the cavity. The endoscope can be applied to medical scenes such as fallopian tube cavity examination, assistance of a duodenoscope in bile duct operation and the like, the application limitation of a traditional endoscope is effectively broken through, ray radiation hazards are reduced, the cross infection risk is reduced, and an innovative technical means is provided for medical diagnosis and treatment.

The present invention provides an embolization device and embolization system. The embolization device includes a spring coil having a storage configuration, an application configuration, and a memory configuration. The memory configuration of the spring coil allows the spring coil to be in the application configuration after being constrained in the fallopian tube. The embolization device of the present invention, with the spring coil as the main structure, is provided with a multi-stage smooth configuration within different length ranges. This ensures that the embolization device can be configured into a supporting segment and a stacking segment after being implanted in the fallopian tube. The multiple supporting segments cooperate to extend deep into the fallopian tube distally, preventing the spring coil from becoming stuck in the fallopian tube, thereby anchoring it in the fallopian tube. The multiple stacking segments collapse and stack into a ball at the proximal end, thereby achieving localized and dense packing of the fallopian tube.

The invention relates to a livestock breeding technology, and discloses a preparation method of a premix for enhancing laying hen production treatment, in the construction of a basic nutrition framework, the construction of a vitamin system is a core project, vitamin A is supplemented by adopting a palmitate form, the stability of the vitamin A in feed processing is ensured, the level of 8000-12000IU should be maintained in each kilogram of feed, and the content of the vitamin A in the feed processing is reduced. According to the fallopian tube mucous membrane composition, the addition amount of the vitamin D3 in the metabolic activity form of 25-hydroxyD3 needs to reach 2000-3000 IU / kg, the vitamin D3 and parathyroid hormone have a synergistic effect, the calcium and phosphorus deposition efficiency can be remarkably improved, particularly, the synergistic effect of B vitamins is worthy of attention, and thiamine (B1) and riboflavin (B2) are compatible according to the proportion of 1: 2. According to the preparation method of the premix for enhancing laying hen production treatment, the growth speed and the laying efficiency of chicken flocks are effectively improved, the eggshell quality is ensured, nutritional diseases such as chondropathy and egg reduction diseases are reduced, and the economic benefits of laying hen breeding are greatly improved.

The utility model relates to the technical field of gynecologic tumor surgery, and discloses a gynecologic tumor surgery model which comprises a uterus model made of hard materials, a first opening and a second opening are arranged on two sides of the uterus model, ovarian models made of elastic materials are arranged on two sides of the uterus model, one end of each ovarian model is inserted into the corresponding second opening, and the other end of each ovarian model is inserted into the corresponding second opening. The two sides of the uterus model are provided with fallopian tube models made of elastic materials, one end of each fallopian tube model is inserted into the corresponding first opening, according to the tumor operation model, multiple models and simulation pieces are installed on the uterus model through multiple connecting structures convenient to disassemble and assemble, all the models and the simulation pieces can be rapidly disassembled and replaced, and the operation efficiency is improved. The operation model can be repeatedly utilized, the whole model simulates the size of the uterus, the material touch feeling is close to the real touch feeling of each organ as much as possible, the model types are complete, various operation simulations can be carried out, the feeling of a doctor during operation simulation is optimized, and the operation level of the doctor can be improved.

The invention discloses a construction method and application of an animal model for HPV (human papillomavirus) pathogenic mechanism research, and belongs to the technical field of animal models. According to the construction method of the HPV fixed-point integration animal model, HPV16 gene knock-in is carried out on the Col1a1 gene locus of a C57BL / 6J mouse through CRISPR / Cas mediated genome engineering. The method comprises the following steps: (1) designing specific gRNA; (2) constructing a knock-in vector Donor vector; and (3) uniformly mixing Cas9 protein, gRNA and a targeting vector Donor vector to obtain an injection compound, performing micro-injection on the injection compound into a mouse fertilized egg, and sending the injection compound back to a pregnant mouse fallopian tube to cultivate offspring so as to generate a gene knock-in mouse. The animal model prepared by the method can be used as a contrast of a cervical cancer precancerous lesion animal model for scientific research.

Compositions, methods, and uses for injecting hydrogels of ablative chemicals are described. The hydrogel is biodegradable and can be formed in situ. The hydrogel is effective to deliver tissue ablative chemicals to a target site. The tissue ablative chemicals delivered by the hydrogel may also be particularly effective for intrauterine ablation (even in the presence of fibroma) or for scar treatment of fallopian tubes by minimally invasive surgery for birth control. The hydrogel may also particularly effectively avoid tissue ablative chemicals from contacting non-target tissue. The hydrogels may be implanted using a variety of delivery carriers, including injections and catheters. The hydrogel may be designed to be limited to a target site for a time of several hours to several days such that target tissue ablation may be performed within a walkable patient. Methods are described for the transcervical placement of an in situ formed hydrogel into the uterus or one or more fallopian tubes.

The invention is suitable for the field of medical imaging, and provides a hysterosalpingography imaging device and method, and the method comprises the following steps: S1, examinee preparation, S2, preparation before imaging, S3, ultrasonic imaging, S4, photoacoustic contrast imaging, and S5, image fusion. According to the imaging method, the photoacoustic imaging technology and the ultrasonic imaging technology are combined, ICG serves as a contrast agent, a high-resolution uterine fallopian tube structure image can be obtained, functional parameters such as blood flow information and blood oxygen information in tissue can be detected through ultrasonic and photoacoustic characteristics, the imaging range is larger by designing a movable area array probe, and the imaging accuracy is improved. The operation is more convenient.

A tubal sterilization system is described. The system includes a catheter having a first lumen and a second lumen, a footplate or plug deployable from the first lumen, and an adhesive deployable from the second lumen. Also described is a method of tubal sterilization. The method includes the steps of positioning a distal end of a catheter having a first lumen and a second lumen near the distal end of a fallopian tube of a subject, deploying a footplate or plug from the first lumen of the catheter to a long segment of the fallopian tube, and deploying an adhesive from the second lumen of the catheter, such that the adhesive remains proximal to the footplate or plug. Also described is a method of sterilization for a male subject.

The invention provides a construction method and application of a chicken fallopian tube embolism model, and belongs to the technical field of animal infection models. The invention provides a construction method of a chicken fallopian tube embolism model based on multi-pathogen infection. The mycoplasma synoviae, the infectious bronchitis virus and the riemerella anatipestifer are utilized to infect the chicken, and the clinical typical salpingemphasis pathological process including cheese-like substance accumulation in a salpingemphasis cavity, serious abdominal air sacculitis complications and related tissue inflammation changes can be accurately reproduced. The model constructed by the invention is high in morbidity, and is suitable for epidemic disease pathogenesis research, drug screening and vaccine potency test. Compared with an existing single pathogen infection model, the model is closer to a clinical reality multi-pathogen cooperative infection scene, and the blank of a standardized multi-pathogen mixed infection induced fallopian tube embolism animal model is filled up.

The invention discloses an intelligent analysis method and system for a contrast image based on generative anti-fact interpretation. The method comprises the following steps: acquiring paired medical image data of an early contrast agent filling period and a late contrast agent dispersion period in a fallopian tube; extracting and calculating a difference value between the late image feature and the early image feature, and constructing a dynamic feature; early image spatial features are extracted, a multi-scale gating fusion up-sampling mechanism is designed, the spatial features and dynamic features are fused step by step, reconstruction of the spatial features is dynamically guided, and an anti-fact image is generated while structural continuity is guaranteed; quantizing a pixel level difference of the generated anti-fact image from the late image; by quantizing the pixel-level difference between the real state and the ideal state and visually presenting the difference part, the diagnosis of a doctor is better assisted, and the efficiency and the accuracy of clinical diagnosis are improved.

The invention discloses a micro-fluidic chip device for a sperm climbing experiment and an experiment method thereof.The device comprises a micro-fluidic chip body and a temperature control device, a sperm sampling pool of the micro-fluidic chip body is filled with a human sperm sample, and the sperm sampling pool is communicated with a sperm enrichment pool through a sperm filtering channel; the sperm climbing channel is vertically fixed at the central position of the sperm enrichment pool through a lap joint block; a treating fluid sample inlet is formed in the top of the sperm climbing channel; a first sperm sampling opening, a second sperm sampling opening and a third sperm sampling opening are sequentially formed in the side surface of the sperm climbing channel; the temperature control device comprises a heater and a temperature controller, and the heater is arranged at the bottom of the sperm enrichment pool and used for maintaining the stability of the temperature microenvironment in the micro-fluidic chip main body; the microenvironment of the fallopian tube is accurately simulated through bionic design, and physiological support is provided for sperm activity evaluation.

The utility model provides a radiography infusion connecting pipe and infusion pump pipeline switching device, including main conduit, branch pipe and pipe joint, branch pipe is aslant communicated with one side of main conduit surface, the top end of main conduit is communicated with first threaded pipe head, branch pipe far away from main conduit far away from one end of main conduit is communicated with second threaded pipe head, and the pipe joint is communicated with the first threaded pipe head. Compared with the prior art, the radiography liquid infusion device has the advantages that water flow pumped by an external infusion pump can impact the cross-shaped notch of the silica gel sealing layer open, an infusion channel is opened, radiography liquid is normally conveyed, when the infusion pump stops conveying, the cross-shaped notch of the silica gel sealing layer can be automatically closed due to the deformation recovery capacity of silica gel, and therefore the radiography liquid can be normally conveyed. By means of the structure, a channel between liquid at the liquid outlet pipe and the conveying pipe can be blocked, the phenomenon that the liquid in the liquid outlet pipe flows back is avoided, liquid medicine pollution generated in the uterus and fallopian tube radiography process is reduced, and therefore the use safety of medical instruments is effectively improved.

The application discloses an oviduct radiography recanalization device, which comprises a double-cavity tube, a guide tube and a guide wire, wherein the double-cavity tube is provided with a liquid injection cavity and a guide cavity, a balloon is arranged on the outer wall of the double-cavity tube and is communicated with the liquid injection cavity, the guide tube is movably arranged in the guide cavity, the guide wire is movably arranged in the guide tube and the distal end of the guide wire can be extended from the distal end of the guide tube, and the recanalization catheter is slidably sleeved outside the guide wire and is provided with a preformed deformation section, wherein the deformation section comprises a first arc-shaped section and a second arc-shaped section.

1. The name of this design product: Teaching model body (uterine cavity and fallopian tube model). 2. Purpose of this design product: This design product is used for teaching demonstration. 3. The key point of the design of this product lies in its shape. 4. The picture or photo that best illustrates the design points: Stereoscopic drawing 1.

Methods and systems are provided for trans-cervical delivery of agents for various purposes, including contraception and tubal patency evaluation. The trans-cervical delivery system comprises at least one port: a tubular shaft coupled to the port, the tubular shaft including at least one hollow channel traversing an interior length of the tubular shaft; and an agent delivery end coupled to the tubular shaft, the agent delivery end including at least one flexible catheter and a plug. The trans-cervical delivery system of the present disclosure integrates a pre-formed wire frame into the agent delivery end that enables self-positioning of the catheter and assists in gaining precise access to the cornual regions of a uterus by an operator. In one example, the trans-cervical delivery system may be utilized for selective delivery of a foam agent to fallopian tubes non-surgically.

This invention discloses a visual guidewire recanalization device for unblocking fallopian tubes, comprising a guidewire body, a sheath, a connecting handle, and a propulsion control system. The core of the guidewire body has an eccentric channel offset from its axis, and the inner wall of the eccentric channel has an inner spiral guide groove. An imaging fiber bundle and an illumination fiber are disposed within the inner spiral guide groove. A spiral layer is sleeved outside the core, and the outer surface of the spiral layer has continuous micro-spiral grooves extending from the proximal end to the distal end. The sheath is sleeved outside the guidewire body. The connecting handle has an irrigation adjustment mechanism communicating with the micro-spiral grooves. The propulsion control system is connected to the proximal end of the spiral layer and is used to drive the rotation and axial movement of the guidewire body. This visual guidewire recanalization device for unblocking fallopian tubes integrates visualization functions and achieves continuous and synchronous fluid irrigation without increasing or even decreasing the guidewire diameter, thereby improving the unblocking effect while maximizing the safety and controllability of the operation.

To provide uses of pertuzumab, which is a first in-class HER2 dimerization inhibitors, and articles of manufacture comprising the same.SOLUTION: A method for extending progression free survival in a population of HER2 + breast carcinoma patients; a method for combining two HER2 antibodies to treat HER2 + breast carcinoma without increasing cardiotoxicity; a method for treating early HER2 + breast carcinoma; a method for treating HER2 + breast carcinoma by co-administering a mixture of pertuzumab and trastuzumab from the same I. v. bag; a method for treating HER2 + metastatic gastric carcinoma; a method for treating HER2 + breast carcinoma with pertuzumab, trastuzumab and vinorelbine; Methods for treating HER2 positive breast cancers with trastuzumab and aromatase inhibitors; and methods for treating low HER3 ovarian, primary peritoneal, or fallopian tube cancers are provided.SELECTED DRAWING: None

The utility model relates to an optimization device in the aspect of micro-fluidic sperm optimization, belongs to the technical field of medical instruments, and solves the problem of low concentration of high-quality sperms after sperm optimization in the prior art. The fallopian tube simulating device comprises a collecting pool and a screening piece, the screening piece is connected with the collecting pool, a screening channel is arranged on the screening piece and provided with an inlet end and an outlet end, the inlet end can be soaked in original semen, the outlet end is connected with the collecting pool, and the fallopian tube is simulated through the screening channel. And performing sperm screening by using the boundary tracking navigation capability of the sperms. According to the sperm screening device, the screening piece is infiltrated into the original sperm, the fallopian tube is simulated through the screening channel, sperm screening is carried out through boundary tracking navigation capacity of sperms, operation is simple, centrifugal operation is not needed in the screening process, sperm DNA cannot be damaged or broken due to peroxidation, the concentration of screened high-quality sperms is improved, and then the fertilization rate is increased.

The invention discloses a traditional Chinese medicine composition for treating infertility, which is prepared from the following raw materials: radix rehmanniae recen, radix paeoniae alba, turtle shell, cortex moutan, peach kernel, ginseng, radix glehniae, medlar, oyster, rhizoma cyperi, radix curcumae, astragalus membranaceus, angelica sinensis, rhizoma anemarrhenae, golden cypress, lotus seed, rhizoma atractylodis macrocephalae, pericarpium citri reticulatae, chicken's gizzard-membrane, radix bupleuri, tetrapanax papyriferus, donkey-hide gelatin, eucommia ulmoides and deer glue. Spleen tonifying, blood nourishing, phlegm reducing and dampness clearing; the effects of soothing liver-qi stagnation, promoting qi and activating blood are achieved; qi is benefited, blood is nourished, and Zhongzhou is promoted to regenerate Qi and blood; promoting blood circulation to remove blood stasis and dredging Chong and Ren qi; the traditional Chinese medicine composition has the effects of clearing heat, promoting diuresis, eliminating dampness and reducing phlegm, can achieve sufficient qi and blood of liver and kidney and smooth Chong and Ren channels, has a good treatment effect on male and female infertility caused by various reasons, and is particularly suitable for female infertility caused by kidney deficiency, weakness, fallopian tube blockage, cold uterus, kidney deficiency type ovulation disorder, obesity, stasis, weakness, blood deficiency and the like; and the traditional Chinese medicine composition is also suitable for male infertility caused by cold sperm, rare sperm, oligospermia and necrospermia due to kidney deficiency.

The invention relates to an absorbable gelatin sponge embolism strip for fallopian tube interventional embolism, which comprises a composite matrix formed by crosslinking gelatin and chitosan through genipin, and the composite matrix has a two-stage pore structure; the embedded developing-degrading adjusting particles are dispersed; the anti-inflammatory drug units are fixed on the inner walls of the micropores through amido bonds. According to the structure, physical anchoring and drug sustained release are achieved through two-stage pores, the PLGA-barium sulfate particles provide a degradable developing function, and the anti-inflammatory drug is triggered to be released in a reducing environment. Compared with an existing stainless steel spring ring, the embolism strip can be completely degraded and absorbed, displacement risks and tissue reaction are avoided, developing is clear and free of interference, a controllable degradation period of 3-6 months can be achieved by adjusting the gelatin / chitosan proportion, and different temporary birth control requirements are met.

The invention provides a degradable spring ring for a female fallopian tube. The degradable spring ring is used for temporary plugging of the fallopian tube in gynecological inflammation treatment and assisted reproduction technologies. The spring ring is made of degradable materials, fibrous protrusions extend on the outer surface of the spring ring, and the spring ring is sequentially coated with an antibacterial medicine coating and a developing coating, so that anti-infection and intraoperative visualization functions are achieved. According to clinical requirements, the first class is divided into two classes: the degradation period is about 3 months, and a PLGA 50: 50 material is adopted and is suitable for preventing reflux of inflammatory media in the fallopian tube inflammation treatment period; the degradation period of the second type is about 2 years, the second type comprises three structures which are PLGA 85: 15, an AZ31 magnesium alloy skeleton or a magnesium alloy / PLGA composite structure, and the long-term plugging requirement in the test tube operation is met. The degradation rate is regulated and controlled through the material ratio, the functional coating and the structural design are combined, biocompatibility, operation safety and clinical adaptability are achieved, secondary operation taking-out can be avoided, and the gynecological diagnosis and treatment effect is remarkably improved.

The present invention addresses the problem of providing a method for operating an FT catheter whereby treatment can be accurately performed even if an operator is not an experienced operator but an operator having a certain degree of skill. The FT catheter (1) is provided with an outer tube (10), an inner tube (20), a fallopian tube lens (30), and a balloon (40). The target site (101) is gradually expanded by repeating the following steps: a first step in which the distal end of the balloon (40) is brought into contact with the target site (101) by pressurizing the balloon (40) and moving the inner tube (20) toward the distal end side; a second step of moving the fallopian tube lens (30) to the rear end side; a third step of further pressurizing the balloon (40) to bring the outer peripheries of the balloons (40) into contact with each other; a fourth step of moving the fallopian tube lens (30) to the tip side and further expanding the balloon (40) to expand the target site; and a fifth step of reducing the pressure of the balloon (40) to reduce the protrusion (41) of the balloon (40).

The application relates to the technical field of balloon catheters, in particular to a strong biocompatibility balloon catheter for oviducts, which comprises a shell, a catheter and a solid pipeline, the inside of the shell is provided with the catheter, one side of the catheter is provided with a liquid pipeline, the side, away from the liquid pipeline, of the catheter is provided with the solid pipeline, one end of the solid pipeline is connected with a solid medicine inlet in a penetrating mode, one end of the liquid pipeline is connected with a liquid medicine inlet in a penetrating mode, then air is injected into the inside of the air bag through the catheter, the air bag is expanded to support the oviduct, when it is needed to deliver medicine, when it is needed to inject liquid medicine, the liquid medicine needed to be used is injected into the inside of the liquid pipeline through the liquid medicine inlet, when it is needed to inject solid medicine, the solid medicine is injected through the solid medicine inlet, different pipelines are used to inject medicine, different medicines are prevented from mixing together to cause medicine pollution, and the use effect on patients is reduced.

The utility model discloses a fallopian tube interventional therapy suite, which relates to the field of fallopian tube interventional therapy and comprises an outer sleeve, a guide nozzle is integrally formed at one end of the outer sleeve, an inner cavity of the guide nozzle is communicated with an inner cavity of the outer sleeve, a transition conical surface is formed at the connection position of one end of the guide nozzle and the outer sleeve, and the transition conical surface is communicated with the guide nozzle. A balloon is integrally formed on the outer wall of the other end of the outer sleeve, an inner sleeve is inserted into the inner wall of the outer sleeve, a corrugated pipe is fixedly connected to one end of the inner sleeve, a straight pipe is fixedly connected to one end of the corrugated pipe, and a wire feeding assembly is connected to one side of the inner wall of the inner sleeve, one side of the inner wall of the corrugated pipe and one side of the inner wall of the straight pipe. A memory assembly is connected to one side of the inner wall of each of the inner sleeve, the corrugated pipe and the straight pipe. By arranging the wire feeding assembly and the memory assembly, the angle of the straight pipe can be actively adjusted by medical staff, the adjusting process is convenient, and the applicability is further improved.

The invention is suitable for the technical field of veterinary drugs, and provides a preparation for salpingitis of laying hens and a preparation method thereof.The preparation is prepared from thyme essential oil, modified resveratrol, modified chitosan, sodium alginate-zinc ion gel microspheres, modified epigallocatechin gallate and mussel mucin. According to the invention, the sodium alginate-zinc ion gel microspheres are intelligently swelled in an acidic inflammation environment of the fallopian tube, and zinc ions are released to inhibit a pathogenic bacteria biological membrane; the zinc oxide nanorods directionally arranged in the magnetic field enhance the tissue permeability and improve the drug concentration of the focus; mussel mucoprotein is covalently crosslinked with tissue protein through catechol groups, so that the residence time is prolonged; activated amino groups of the modified chitosan are combined with negative charges of mucous membranes to form a physical barrier to block pathogen adsorption; the thyme essential oil destroys bacterial cell membranes, so that the permeation efficiency of subsequent antibacterial components is improved; the free radical scavenging capacity of the modified resveratrol-quercetin eutectic is improved compared with that of a monomer.