251 results about "Oviduct" patented technology

A Chinese medicinal composition for treating alopecia and leukotrichia contains thirty Chinese traditional medicines such as fineleaf schizonepeta herb, divaricate saposhnikovia root, ginger, rehmannia root, tree peony bark, red peony root, kuhseng, densefruit pittany root-bark, tuckahoe, oriental waterplantain tuber, belvedere fruit, danshen root, ginseng, safflower, jujube, fleece-flower root, mulberry fruit, angelica, drynaria, desertliving cistanche, prepared rehmannia root, solomonseal rhizome, eucommia, black sesame seed, black soyhean, chinese caterpillar fungus, forest frog oviduct, etc. Oral administration in combination with external application of the composition is adopted so that medicine factor directly acts on dermal layer of scalp for activating hair follicle cell regeneration, adjusting sebum secretion, improving scalp metabolism, supplementing nutrition required by hair, holding hair, blackening hair and caring hair.

Transgenic avians which produce proteins in their oviduct tissue having modified oligosaccharide structures and methods of making such avians are disclosed herein. The invention also includes the modified proteins produced in the transgenic birds.

PCT No. PCT/SE97/00610 Sec. 371 Date Dec. 8, 1998 Sec. 102(e) Date Dec. 8, 1998 PCT Filed Apr. 11, 1997 PCT Pub. No. WO97/37587 PCT Pub. Date Oct. 16, 1997Device and method for collecting endogenous gaseous nitric oxide (NO), in the urogenital tract, for example in the urinary tract and in the uterus and oviducts. According to one embodiment, a NO permeable, liquid impermeable inflatable body (16) is positioned in the urethra (5) surrounded by the prostate gland (17), whereby an additional inflatable body (4) positioned in the bladder (2) serves to seal off the bladder from the urethra and helps in the positioning of the device. The present invention further relates to a method and a system for use in the diagnosis of inflammatory states in said organs.

Transgenes encoding exogenous proteins are stably integrated into embryonic stem cells and are present in the somatic tissue of transgenic or chimeric birds. The transgenes encode exogenous proteins and are expressed in any of endodermal, ectodermal, mesodermal, or extra embryonic tissue. Tissue specificity is provided by selecting the content of the transgene accordingly. Transgenic birds whose genome is comprised of trangene derived exogenous DNA express exogenous proteins with tissue specificity, and specifically express exogenous proteins in the tubular gland cells of the oviduct to concentrate exogenous proteins in egg white..

Transgenes encoding exogenous antibodies are stably integrated into donor cells and are present in the somatic tissue of chimeric birds. The transgenes encode exogenous antibodies and are preferably expressed in the oviduct for collection in the egg. Tissue specificity is provided by selecting the content of the transgene accordingly. Birds whose genome is comprised of trangene-derived exogenous antibody-encoding DNA express exogenous antibodies having desirable chemical properties with increased therapeutic utility compared to antibodies derived from bacterial expression systems.

The present invention provides novel isolated nucleic acids that comprise an avian nucleic acid sequence comprising a ovomucoid gene expression control region. The ovomucoid promoter region of the present invention will allow expression of an operably linked heterologous nucleic acid insert in a transfected avian cell such as, for example, an oviduct cell. The isolated avian ovomucoid of the present invention may be operably linked with a selected nucleic acid insert, wherein the nucleic acid insert encodes a polypeptide desired to be expressed in a transfected cell. The recombinant DNA of the present invention may further comprise a polyadenylation signal sequence. The present invention further includes expression vectors comprising an isolated avian ovomucoid gene expression control region of the present invention, and transfected cells and transgenic avians comprising the expression vectors.

The invention discloses a medicine for treating woman sterility, wherein the medicine mainly comprises the traditional Chinese medicinal preparation of corinth pink soups, as well as burred tuber, zedoary, root of red rooted saliva and leonurus heterophyllus sweet.

Transgenes encoding exogenous proteins are stably integrated into embryonic stem cells and are present in the somatic tissue of transgenic or chimeric birds. The transgenes encode exogenous proteins and are expressed in any of endodermal, ectodermal, mesodermal, or extra embryonic tissue. Tissue specificity is provided by selecting the content of the transgene accordingly. Transgenic birds whose genome is comprised of trangene derived exogenous DNA express exogenous proteins with tissue specificity, and specifically express exogenous proteins in the tubular gland cells of the oviduct to concentrate exogenous proteins in egg white.

The invention discloses a preparation method and an application of a tissue slice for observing temporal-spatial distribution of early embryo development in vivo. The preparation method comprises the following steps that 4% paraformaldehyde fixing, upward gradient ethanol dehydration, wax dipping, embedding, serial section, baking, dewaxing and downward gradient ethanol rehydration are performed in sequence on oviducts or uterine tissues which contain mice embryos in every period, and finally, after haematoxylin-eosin staining is performed on the tissues in the slice, neutral gum is used for sealing the slice, or after immunofluorescence histochemical staining is performed on the slice, a fluorescence resistant quenching sealing agent is used for sealing the slice. The tissue slice disclosed by the invention can be used for manufacturing a map of early mice embryo development and detecting the expression of Crb3 in the mice embryos in every period of development in vivo. The preparation method has the advantages that positions of all organs in the embryos can be relatively fixed, so that the position change of embryo cells in a genital tract and the continuity of embryo development can be conveniently observed, the structure is clear, and the tissue slice is convenient to store.

The invention discloses a traditional Chinese medicine composition for beautifying skin. The effective components of the composition consists of the following raw medicines in daily dosage: 2 to 8 grams of ginseng, 3 to 6 grams of angelica, 3 to 9 grams of red sage roots, 100 to 700 milligrams of forest frog oviducts and 145 to 900 milligrams of grape seed extract. The medicine composition can be added with microcrystalline cellulose or magnesium stearate as auxiliary materials to prepare tablets, or be added with stearic acid, glyceryl monostearate, hydrogenerated polyisobutene, olive oil, methyl glucose sesquistearate, glycerin, azone, ethyl nipagin ester and distilled water as the auxiliary materials to prepare cream. The composition has the advantages of high product safety performance, no toxic or side effect, speckle removal, wrinkling resistance, skin aging improvement, good skin beautifying efficacies, and stable and reliable product quality. In addition, the composition is rich in resources of the raw medicines, scientific and reasonable in formulation and simple in preparation process, and meets the requirements of industrial production.

The invention discloses an oviduct recanalization therapeutic catheter with an air bag and capable of automatically being fixed. The oviduct recanalization therapeutic catheter comprises a taper-shaped fixator, an outer sleeve positioned behind the taper-shaped fixator, a main catheter penetrating through the taper-shaped fixator and the main sleeve and a detachable inner-layer oviduct catheter mounted in the main catheter. The oviduct recanalization therapeutic catheter is simple in structure, has multiple using methods and can be applied to multiple therapeutic methods. When the oviduct recanalization therapeutic catheter is used, traumas to patients' uterine necks caused by multiple catheter inserting during therapeutic processes are effectively avoided, clinical operation difficulty is greatly reduced, and meanwhile, therapeutic costs and expenses are saved.

The invention provides a Chinese herbal medicine containing feed for laying hens. The feed contains the following raw materials in parts by weight: 50-80 parts of corn flour, 20-30 parts of rice flour, 15-25 parts of millet flour, 10-20 parts of pumpkin flour, 40-60 parts of sweet potato flour, 50-70 parts of bean cake meal, 80-90 parts of rapeseed cake meal, 90-120 parts of rice bran, 25-40 parts of highland barley powder, 35-50 parts of fish meal, 20-40 parts of bone meal, 10-18 parts of conch powder, 35-60 parts of calcium hydrogen phosphate, 60-80 parts of rock flour, 20-30 parts of common salt, 40-50 parts of sodium bicarbonate, 5-15 parts of compound trace elements, 4-10 parts of multivitamins, 10-25 parts of amino acids, 5-8 parts of taraxacum mongolicum, 8-15 parts of folium artemisiae argyi, 12-20 parts of crataegus pinnatifida, 5-15 parts of Chinese angelica, 5-20 parts of whiteflower patrinia herb and 5-10 parts of fructus liquidambaris. The feed for the laying hens is rich in nutrition, contains Chinese herbal medicine ingredients and is green and environmentally friendly, so that the laying hens can be far away from diseases, oviducts of the laying hens can be unobstructed, eggs are high in quality and large in number, and thus nutritional requirements of people can be met.

The invention relates to a traditional Chinese medicine compound pharmaceutical composition and a preparation method and application thereof. The traditional Chinese medicine compound pharmaceutical composition contains clove, Salvia miltiorrhiza, dodder, epimedium, fructus cnidii, radix codonopsitis, radix astragali, angelica, rhizoma ligustici wallichii, phellodendron, radix scutellariae, rhizoma coptidis, Gardenia, ebony, hawthorn and kaki calyx. The traditional Chinese medicine compound pharmaceutical composition has the efficacies of replenishing Qi to invigorate the spleen, warming uterus and tonifying Yang, tonifying kidney and consolidating, nourishing blood and tonifying Qi, activating blood flow and removing blood stasis and clearing heat and detoxicating and has the functions of preventing and curing the inflammations of the fallopian tubes of the laying fowls. The traditional Chinese medicine compound pharmaceutical composition has definite curative effect, rapid action, safe use and no toxic and side effects or residuals, meets the demand of safety of animal-derived foods, is easy to realize industrial production and does not have pollution on the environment. The invention also provides a preparation method of the traditional Chinese medicine compound pharmaceutical composition and the application of preventing and curing the inflammations of the fallopian tubes of the laying fowls and improving the laying function. The traditional Chinese medicine compound pharmaceutical composition can be a powder. The invention also provides a feed containing the traditional Chinese medicine compound pharmaceutical composition.

The invention provides an animal model with male reproductive disorders of a non-human mammalian animal, as well as a preparation method and application of the animal model, and further identifies the functions of a Prss37 gene and a protein. The Prss37 gene of the animal model is inactivated, thereby affecting the appearance of ADAM3 in mature sperms produced by the animal model, indirectly affecting the combination of the sperms-zona pellucida and the migration of the sperms from the uterus to the oviduct and resulting in the serious male reproductive disorders. The model, the Prss37 gene and the protein thereof can be used for screening ADAM3 ripening accelerators, as well as sterility infertility treatment agents or contraceptive medicaments.

The invention discloses poultry semen diluent for maintaining the sperm motility and prolonging the insemination time. Every 1000ml of diluent comprises the following components: 0.5g to 1.4g of magnesium chloride, 1g to 1.3g of potassium citrate, 8g to 10g of sodium acetate, 10g to 20g of fructose, 10g to 25g of sodium glutamate, 1g to 5g of multi-vitamin and water. The poultry semen diluent has the beneficial effects that the insemination time can be prolonged, the number of the raised breeder cocks can be reduced, the stress on a breeder hen caused by the artificial insemination can be alleviated, the egg laying rate can be improved, the fertility rate can be increased, the incidence probability of the oviduct inflammatory can be reduced, and the quality of the chicks can be improved.

The invention belongs to the field of traditional Chinese medicine, and particularly relates to a medicine composition capable of improving sleep quality and a preparation method of the medicine composition as well as an application of the medicine composition. The medicine composition comprises the following constituents in parts by weight: 0.1 part to 0.3 part of a forest frog's oviduct, 3 parts to 10 parts of spina date seed, 1 part to 5 parts of polygala tenuifolia, 1 part to 5 parts of poria cocos, and 0.5 part to 3 parts of artichoke; the preparation method comprises the following steps: weighting the spina date seed, the polygala tenuifolia, the poria cocos, forest frog's oviduct powder and artichoke powder; extracting the spina date seed, the polygala tenuifolia and the poria cocos in water; concentrating the filtrate acquired in the last step into an extract; drying the extract to acquire extracting powder; mixing the extracting powder with the forest frog's oviduct powder and the artichoke powder uniformly to acquire the medicine composition capable of improving the sleep quality. The medicine composition is used for preparing the medicine capable of improving and curing the sleep quality or health food. The medicine composition does not have any side effect. Therefore, the medicine composition is suitable for people for a wide range.

The invention relates to a traditional Chinese medicine composition for curing oviduct obstruction. The traditional Chinese medicine composition is prepared from the following raw materials in part by weight: 15-25 parts of radix salviae miltiorrhizae, 10-20 parts of motherwort, 10-20 parts of beautiful sweetgum fruit, 10-20 parts of cuscuta chinensis, 10-20 parts of achyranthes bidentata, 7-13 parts of radix curcumae, 7-13 parts of radix paeoniae rubra, 7-13 parts of ligusticum wallichii, 7-13 parts of rhizoma sparganii, 7-13 parts of zedoary, 7-13 parts of laminaria, 7-13 parts of spina gleditsiae, 7-13 parts of trogopterus dung, 7-13 parts of rhizoma cyperi, 7-13 parts of folium artemisiae argyi, 7-13 parts of angelica sinensis, 7-13 parts of rheum officinale, 7-13 parts of radix paeoniae alba, 7-13 parts of herba epimedii, 7-13 parts of cowherb seeds, 3-9 parts of peach kernels, 3-9 parts of myrrh, 2-4 parts of pericarpium citri reticulatae, 2-4 parts of asarum, 2-4 parts of cantharides and 2-4 parts of carthamus tinctorius. The traditional Chinese medicine composition has the advantages of stable curative effect, short curative time and simple preparation method.

The invention discloses a Chinese medicament for treating extrauterine pregnancy, which consists of the following raw material medicaments in part by weight: 4 to 6 parts of Chinese angelica, 2 to 4 parts of liquoric root, 2 to 4 parts of red paeony root, 2 to 4 parts of peach seed, 2 to 4 parts of cassia twig, 2 to 4 parts of tree peony bark, 2 to 4 parts of rhizoma corydalis, 2 to 4 parts of medicinal cyathula root, 2 to 4 parts of common burreed rhizome, 2 to 4 parts of zedoary, 2 to 4 parts of nutgrass galingale rhizome, 1 to 3 parts of cassia bark, 1 to 3 parts of cowherb seed, 3 to 5 parts of sappan wood, 1 to 3 parts of danshen root, 2 to 4 parts of dahurian patrinia herb, 2 to 4 parts of spreading hedyotis herb, 2 to 4 parts of Japanese milkwort herb and 1 to 3 parts of motherwort herb. The Chinese medicament for treating the extrauterine pregnancy has strong effects of killing embryos, and has obvious effects of decomposing and absorbing pelvic hematoma masses and blood. The Chinese medicament conservatively treats the extrauterine pregnancy, can maintain integrity of uterine tubes, does not damage tube walls, and can furthest improve fertility of patients.

The invention relates to a kidney-warming yang-supporting medicine composition and a preparation method thereof. An active component of the medicine composition is prepared from, by weight: 10-15 parts of ginseng, 4-18 parts of Chinese magnoliavine fruit, 100-450 parts of epimedium, 10-15 parts of Mongolian milkvetch root, 10-15 parts of spine date seed, 10-15 parts of dan-shen root, 60-225 parts of raw rehmannia root, 10-45parts of hairy antler pilose antler, 0.5-3 parts of forest frog's oviduct, 10-15 parts of tubular stalactite, 10-120 parts of tuber onion seed, 60-225 parts of common cnidium fruit, 10-135 parts of common fenugreek seed, 0.5-3 parts of deer penis and testes, 10-75 parts of ox penis and testes, 10-45 parts of dog penis and testes, 10-15 parts of sea horse, 10-15 parts of large dried shrimp, 1-7.5 parts of borneol, and 100-450 parts of tussah silkworm chrysalis. As a result of pharmaceutical effect experiments, the medicine composition and the formula provided by the invention assists in substantially treating kidney-yang deficiency syndrome. The effect of the medicine composition is better than compositions not provided by the invention.

The invention belongs to the technical field of pig transgenosis and particularly relates to a method for producing transgenic pigs through overexpression HOXA10 genes. The method is characterized in that constructed HOXA10 gene expression carriers are subjected to lipofection and sulfate (G418) screening to obtain HOXA10 transgenic cell lines with stable expression; the HOXA10 transgenic cell lines are transplanted into denucleated pig oocytes with HOXA10 transgenic pig fibroblasts as nuclear donors through an artificial nuclear transplantation method to form reconstructed embryos; the reconstructed embryos are transplanted into a receptor sow oviduct, and after a sow gives birth to the HOXA10 transgenic pigs and molecular identification is conducted, masculine HOXA10 transgenic pigs are screened out. The transgenic pigs obtained through the method provide materials for research about the mechanism of improving the reproductive capacity through the HOXA10 genes and provide an animal model for revealing other functions of the HOXA10 genes.