482 results about "Uterus" patented technology

The invention provides a strain of lactobacillus plantarum YS-AG23 with high antioxidant activity, and a rhizoma polygonati and radix angelicae sinensis fermented product obtained by fermenting rhizoma polygonati and radix angelicae sinensis with the strain of lactobacillus plantarum YS-AG23. In a D-galactose induced premature ovarian failure mouse model, the fermentation product can regulate up the levels of antioxidant and stress protection genes SOD2 and HO-1 and an anti-aging gene SIRT1 by regulating down the expression of a key gene AGER of an inflammation and oxidative stress pathway, so that the oxidative stress and inflammatory response of model mouse ovarian tissues are remarkably reduced; meanwhile, the serum hormone level can be specifically adjusted, the serum estradiol (E2) level can be increased, the follicle stimulating hormone (FSH) and luteinizing hormone (LH) levels can be reduced to be close to the normal range, the expression of anti-mullerian hormone (AMH) and hormone regulatory gene LHR of ovarian reserve markers can be up-regulated, the proliferative activity and estrogen secretion function of follicular granulosa cells can be improved, and the effect of preventing ovarian reserve is achieved. The wet weight of atrophic uterus and ovary of the model mouse is remarkably increased, uterine and ovary atrophy is effectively reversed, and the ovarian reserve function of the D-galactose induced premature ovarian failure model mouse is recovered. Besides, in an H2O2-induced human dermal fibroblast aging model, the yeast can improve the activity of aging cells in a concentration-dependent manner and reduce the level of reactive oxygen species (ROS) in the cells; in addition, by up-regulating the expression of a collagen synthesis key gene COL1A1 and down-regulating the expression of a cell senescence marker gene p16, skin cell senescence caused by oxidative stress can be effectively improved. In conclusion, the polygonatum sibiricum and angelica sinensis leavening can synchronously improve premature ovarian failure and skin cell senescence caused by oxidative stress by accurately regulating and controlling oxidative stress, inflammatory response and tissue function related genes, and has wide application potential.

An anti-hemorrhaging device includes an elongate body, a flexible looped segment, a shield, and an inflatable seal. The elongate body is configured to attach to a vacuum source. The flexible looped segment is attached to the elongate body includes a plurality of holes on an inner circumference thereof. The flexible looped segment is configured to be placed in a uterus. Activation of the vacuum source is configured to pull vacuum through the plurality of holes so as to collapse the uterus upon insertion of the elongate body into the uterus. The shield is folded around an exterior circumference of the looped portion and has edges that extend radially inwards relative to the flexible looped distal section. The shield is configured to prevent tissue from occluding the plurality of holes when vacuum is applied. The inflatable seal is attached to the elongate body and is configured to seal the uterus.

A lumen organ model and an endoscope training system are provided. A luminal organ model (3) is provided with: a model body (11) comprising a hollow lumen body having a lumen surface that simulates at least the lumen of a luminal organ such as the stomach, the large intestine, the bladder, the paranasal sinus, or the uterus; a light source device (13) that emits light in a light-emitting region disposed at at least one predetermined observation site corresponding to a training purpose on the lumen surface of a model body (11) comprising a lumen; and a processor (27) that selectively switches light-emitting regions that emit light by controlling the light source device (13).

Systems, devices, and methods are provided that control, support, and / or elongate a cervix to treat pregnancy complications and / or delay an onset of labor so that a gestational period for a fetus may be extended, thereby preventing preterm labor and delivery of the fetus. The cervical control systems may include a main body configured for placement in a vagina. The main body has in internal passageway configured for acceptance of a cervix therein and an inflatable and / or expandable inner cuff extends from portion of the internal passageway. The inner cuff may be expandable inward toward the cervix, or downward away from the uterus, or both inward and downward so that the inner cuff may engage, or grip, the cervix thereby holding the cervical control system in place while compressing the cervix closed, elongating the cervix, and / or adjusting an angle of orientation of the cervix.

The invention relates to the technical field of embryo culture platforms, in particular to a microfluidic-AI monitoring-metabolism regulation embryo culture platform and a preparation method thereof.The microfluidic-AI monitoring-metabolism regulation embryo culture platform comprises a microfluidic culture system used for achieving embryo culture, metabolite removal and culture medium replacement; the artificial intelligence monitoring system is used for remotely monitoring the embryonic development state in real time and predicting the embryonic development condition; the metabolism regulation and control system is used for feeding back and optimizing culture conditions online according to an artificial intelligence monitoring result and a metabolite analysis result; the intelligent control module is electrically connected with the micro-fluidic culture system, the artificial intelligence monitoring system and the metabolism regulation and control system, and the micro-fluidic culture system can accurately control the culture environment on the micrometer scale, including temperature, pH value and gas composition parameters. The dynamic fluid environment is closer to the in-vivo physiological environment of the embryo. The system can simulate periodic nutrient supply and metabolic waste removal in the uterus, and provides optimal growth conditions for embryos.

The present invention provides, in various embodiments, systems and methods for robotic manipulation of a patient's anatomy, such as the uterus, during surgical procedures.

A visual embryo transfer catheter system includes a handle and a visualization sheath which is configured to be coupled to the handle and to be inserted into the uterus of a patient. The visualization sheath includes at least three lumens, including a first lumen for a scope assembly including a camera and an illumination source, a second lumen to permit passage of an embryo transfer catheter which is configured to deliver an embryo to the uterus upon imaging of the uterus with the camera when the uterus is illuminated by the illumination source, and a third fluid supply lumen for inflow and outflow of fluid to and from the uterus. Further embodiments include methods for transferring an embryo into a uterus of a patient under visual guidance, and kits for performing a visualized embryo transfer.

The invention discloses an ovary-targeting mRNA liposome nanoparticle, a preparation method, a drug compound, a targeting delivery system and application, and relates to the technical field of liposome granules, the ovary-targeting mRNA liposome nanoparticle comprises the following components by mass: 20%-80% of SM-102, 1%-20% of PEG2000, 5%-40% of CHO-HP, 1%-20% of DSCP, and 0.01%-10% of targeting polypeptide, the target polypeptide comprises at least one of the following sequences: LVYKDPARPNTQK, RCGPCRLSSSDCGGPRTQPMACDLP, and CALCRRSTSDCGGPKDHPLT (recombinant human serum albumin), and the target polypeptide comprises at least one of the following sequences. The present invention provides a liposome nanoparticle for targeted ovary and uterus delivery of mRNA. The lipidosome nano-particles are specially researched, developed and designed for mRNA, have a good targeted delivery effect in mRNA in-vivo delivery, and can be applied to the field of targeted drug delivery of ovaries and uteruses. When in use, the kit can be directly prepared with a specific mRNA sequence for use, so that different application requirements can be flexibly met.

The invention belongs to the technical field of medical apparatus and instruments, and particularly relates to a gynecological endometrium sampling device which comprises a liquid negative pressure extraction mechanism, a liquid collection and storage mechanism and a self-adaptive uterus sampling mechanism, the liquid collection and storage mechanism is fixedly arranged on the liquid negative pressure extraction mechanism, and the self-adaptive uterus sampling mechanism is fixedly arranged on the liquid negative pressure extraction mechanism. The self-adaptive uterus sampling mechanism is arranged in the liquid negative pressure extraction mechanism and is in sliding connection with the liquid negative pressure extraction mechanism; liquid in the uterus can be sucked and removed firstly, then comprehensive sampling is conducted, a sampled sample is protected and stored, the sample quality is effectively improved, and the sampling failure problem is avoided.

The invention relates to the crossing field of a medical rehabilitation training technology and a computer simulation technology, in particular to a postpartum rehabilitation simulation training demonstration device and a use method thereof. The training assembly comprises a dredging massage piece, a uterus simulation piece and a moxibustion piece which are arranged in the model body; the driving assembly comprises a transmission piece and a pressing piece; the transmission piece comprises an external connection block arranged in the model body and a transmission groove formed in the upper end face of the external connection block. The pressing piece comprises a lower pressing shaft arranged on the inner wall of the model body and a rotating shaft arranged on the inner side of the lower pressing shaft; massage rehabilitation of the abdomen, the mammary gland and the uterus can be achieved through a plurality of components in the training assembly, the training requirements of personnel are met, meanwhile, downward pressure is converted into power of the triggering assembly through the pressing piece, and whether the force is appropriate or not is judged through responses of the response pieces at different positions; and the accuracy of the pressing position and force during personnel training is improved.

The invention relates to the technical field of medical information, in particular to a placenta position detection system and method based on MRI, and the method comprises the steps: obtaining target MRI image data, carrying out the image segmentation of the target MRI image data, and extracting the three-dimensional models of a placenta, a uterus and a cervix; based on the three-dimensional model, identifying the position relationship between the placenta and the cervix uteri, judging the type of the placenta, and evaluating the placenta implantation risk to generate risk early warning information; and displaying a three-dimensional visual model of the placenta and the uterus, and marking a high-risk area on the three-dimensional visual model based on the risk early warning information. The placenta position detection efficiency, precision and automation are improved, full-process automatic detection can be achieved, and personal errors are reduced.

The invention aims to provide a health-preserving tank with multiple functions, the health-preserving tank comprises a negative pressure air bag and a magnetic uterus which is mounted on the negative pressure air bag and can be adsorbed on the skin of a human body, a connector is arranged in the magnetic uterus, a magnetic needle for performing magnetic moxibustion on acupuncture points of the human body is slidably arranged in the connector, a medicine feeding mechanism is arranged in the magnetic needle, and the medicine feeding mechanism is connected with the negative pressure air bag. A driving mechanism and a heating mechanism are arranged in the magnetic uterus, the driving mechanism can control the magnetic needle and the medicine feeding mechanism to longitudinally and intermittently slide, stimulate and massage acupuncture points and feed medicine to the acupuncture points, and the magnetic needle is heated under the work of the heating mechanism, so that thermomagnetic acupuncture and pharmacological recuperation on the acupuncture points are realized. A plurality of magnetic moxibustion with different effects, such as pharmacological magnetic moxibustion and heating magnetic moxibustion, are integrated on one health-preserving tank, so that the health-preserving tank can strengthen the recuperating effects of dredging meridians and collaterals, regulating qi and blood and relieving swelling and pain through the mutual combination of massage, pharmacology and heating or the unified matching of the health-preserving tank and magnetic therapy.

The present invention provides a functional heating belt for relieving uterine cold in women, which is used to relieve the symptoms of uterine cold in women and includes: a belt main body, on which a non-functional area and a functional area are provided, wherein: the non-functional area is an elastic woven belt with a single-layer structure, which is arranged corresponding to the waist side area and the back area of the human body, and the elastic woven belt is used to adjust the size of the belt main body and the pressure on the human body; the functional area is a double-layer open structure, which is arranged corresponding to the abdominal area of the human body and is used to warm the abdominal part of the human body, and conductive heating yarns for realizing the heating function of the belt main body are mixed in the warp and weft yarns of the functional area. The functional heating belt for relieving uterine cold in women provided by the present invention improves the heat generation mode and heat conduction path, aiming to uniformly and directionally transfer the heat effect to the medicine bag, accelerate the slow release of the medicine, and then enable the medicine molecules and heat to act on the human body simultaneously, promote the human body to absorb the effective components of Chinese herbal medicine, and effectively relieve the pain of uterine cold.

The present disclosure relates to devices and methods for accessing the reproductive tract of an animal, particularly via the animal's vagina, and deploying reproductive material within the uterus. The device and methods of the disclosure may be particularly suited for embryo transfer processes, such as performed in livestock e.g., cattle.

Uses of one or more systems, devices, computer-implemented methods, and / or computer program products provided herein involve associating background sounds with fetal heart rate (FHR). A system may include a processor that may execute computer executable instructions stored in a memory that, when executed by the processor, facilitate execution of operations that include: detecting a defined average FHR of a plurality of periods of a fetus with an ultrasound fetal monitoring system (FMS); associating the defined average FHR for the plurality of periods with sounds outside the uterus of the fetus to identify and record one or more audio patterns that may cause the defined average FHR for the plurality of periods within the fetus; and replaying the one or more audio modes to the fetus after applying the first level of modification to the one or more audio modes based on the characteristics of the uterus.

The invention relates to a formula of a tea drink, and relates to the technical field of homology of medicine and food, and the formula is prepared by compounding nine components of double-petal red rose, Hetian jade jujube slices, dried mulberry, longan pulp, Ningxia wolfberry, Xinhui dried orange peel, raspberry, Hunan lotus seed pulp and licorice slices according to a specific proportion. Synergistic interaction is realized through triple action mechanisms, the liver soothing and depression relieving of the double-petal red rose is taken as a regulation and control core, the cortisol level is reduced, and endocrine imbalance is improved; on the basis of benefiting qi and nourishing blood by jujube slices and Chinese wolfberry fruits, dried mulberries and raspberries are enriched with natural folic acid and antioxidant substances, so that the egg cell quality and reproductive microcirculation are improved in a targeted manner; longan-Hunan lotus seed meat is used for warming uterus and tonifying spleen, and dried orange peel-licorice tablets are combined to enhance component absorption and compatibility stability. The preparation method comprises the steps of gradient drying, precise mixing and cobalt-60 irradiation sterilization. According to the scheme, the absorption bottleneck of traditional substitutional tea is broken through, the bioavailability is improved, and the compound sub-health problems of female endocrine disorder, follicular development disorder and cold uterus and weak body are quantitatively solved.

The invention relates to the technical field of crossing of medical instruments and biomedical engineering, and discloses a vaginal ultrasonic probe protective sleeve integrated with a uterus myoelectricity monitoring flexible electrode, which comprises a sleeve body and a flexible sensing module integrated on the head of the sleeve body, the flexible sensing module comprises a flexible substrate, a flexible electrode array and a packaging layer from inside to outside. The flexible sensing module is integrated at the head part of the sleeve body, and the flexible sensing module is provided with the flexible substrate, the flexible electrode array and the packaging layer from inside to outside, so that on the premise of not changing the existing vagina ultrasonic examination operation process and not interfering the ultrasonic image quality, the disposable protective sleeve is transformed, and the vagina ultrasonic examination efficiency is improved. Therefore, a high-performance bio-electricity signal collection interface is formed while the isolation function is achieved, and real-time, synchronous and same-body-position collection of uterus ultrasonic images and cervical opening electromyographic signals is achieved.

1. Name of the product in this design: Warm Palace Treasure (without doll). 2. Purpose of this design: For warming the uterus. 3. The key point of the design of this product lies in its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The invention discloses a special antenatal examination bed which is more suitable for a pregnant woman to use during outpatient antenatal examination. Two bed plates with soft cushions are arranged on a bed main body, a front bed plate and the plane of the bed main body are inclined by 30 degrees, a square groove is formed between the front bed plate and a rear bed plate, and annular handrails are arranged at the positions, on the two edges of the square groove, of the bed main body; semi-elliptical baffles are arranged on the two sides of the front end of the bed main body, and soft cushions are arranged on the inner sides of the two semi-elliptical baffles; the rear end of the bed body is movably connected with a rubber mat. When the bed is used, a pregnant woman holds the special antenatal examination bed on the annular handrail, the head is directly placed on the pillow, the feet are directly placed on the rubber mat without taking off shoes, and the waist is located in the square groove; a pregnant woman lies on the special antenatal examination bed inclining by 30 degrees, an examiner directly takes a tape to penetrate through the square groove to measure the uterus height and the abdominal girth, and if the pregnant woman is nervous, the nervous condition can be relieved by two hands through the annular handrails; the legs of the pregnant woman bend and expand outwards, and four-step palpation is conducted; after antenatal examination is finished, the pregnant woman can easily get up by pulling the annular handrail with two hands, and the working intensity of examinees is relieved.

1. The name of the design product: heating uterus waistband. 2. The use of the design product: for heating. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: design 1 perspective view. 5. Design 1 is designated as the basic design.

The utility model relates to the technical field of uterine stent pushing, in particular to a uterine stent pushing device which comprises a pushing assembly, a pushing assembly and a pushing assembly. The pushing assembly comprises a sleeve; the push rod is connected to one end of the sleeve; the sleeve U-shaped opening is formed in the other end of the sleeve; and a limiting block is arranged outside the sleeve in a sleeving manner. The U-shaped opening at the front end of the plastic sleeve is small in front and large in rear, so that the uterus support can be effectively fixed and does not fall off in a free state.

An intra-uterine monitoring system is described. The system has an intra-uterine device, shaped and dimensioned for implantation in a uterus, and a receiver device. The intra-uterine device is for measuring conditions within the uterus to generate sensor data and for acting as a contraceptive device to prevent pregnancy. The receiver device is for wirelessly receiving the sensor data generated by the intra-uterine device implantable sensor device.

1. The name of the design product: controller. 2. The use of the design product: the design product is used for intelligent wear, waistband, knee pad, uterus warming treasure, shawl and massage, electric heating, vibration type intelligent products. 3. The design points of the design product: in shape. 4. The picture or photo that can best show the design points: perspective view 1.

A wearable birthing simulator and method of operating thereof are disclosed. The simulator includes a housing that is securable to a subject and the housing defines an opening. Positioned within the housing is a uterus simulator and a removable fetal model contained therein. Coupled to the uterus simulator is a birth canal simulator. A birthing device comprises an actuator assembly in communication with the controller for automatically moving the fetal model towards the birth canal simulator. One or more sensors are mounted to the housing and are electrically connected to the controller for detecting movement of the fetal model by the birthing device. The feedback device is configured to provide the haptic feedback to the subject in response the movement of the fetal model toward the birth canal simulator. The disclosed simulator may be used to simulate a variety of childbirth scenarios.

The invention discloses a ritodrine-loaded decellularized amnion matrix temperature-sensitive hydrogel and pharmaceutical application thereof, i.e., an amnion is subjected to decellularization treatment and then is digested by pepsin to obtain blank gel, and then drug loading is performed to obtain drug-loaded gel for treating premature delivery. The ritodrine-loaded vagina temperature-sensitive gel with high biocompatibility is prepared by taking a premature delivery treatment drug ritodrine commonly used in clinic as an active compound and taking an acellular amniotic membrane as a carrier, so that the enrichment of the drug in the uterus is improved, and the systematic exposure of the drug and the side effects caused by the systematic exposure are reduced. The invention provides a medicine delivery and treatment strategy based on the uterus first-pass effect for premature delivery treatment, and provides a simple and effective technical scheme for developing clinically effective premature delivery treatment medicines and reducing side effects of clinical medicines.

1. The name of the design product: warm uterus waistband (graphene heating). 2. The use of the design product: for physiotherapy and warmth of the waist and abdomen. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1.

1. Name of the Design Product: Intelligent Warming Uterus Music Belt. 2. Use of the Design Product: An intelligent warming uterus belt with audio playback function. 3. Design Key Points of the Design Product: The combination of shape and pattern. 4. Picture or Photograph that Best Illustrates the Design Key Points: Perspective View 1.

1. The name of the design product: warm uterus belt. 2. The use of the design product: for warm uterus belt with heating and massage functions. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: perspective view 1. 5. Other circumstances that need to be explained: other: mark A part as transparent material.

The utility model discloses a uterus scraper with a temporary storage function, which comprises a tube body, a storage cavity is arranged in the tube body, a slidable curette part is arranged on the outer wall of the tube body, a sealing curette head is arranged at the port of the tube body and on one side close to the inlet of the storage cavity, and a piston part is arranged in the storage cavity. By designing the sealed curette head, substances scraped by the curette piece on the inner wall of the uterus can be effectively received, and residual tissues are prevented from easily falling off from the curette head; by designing the tube body with the storage cavity and matching the tube body with the piston piece, if a large amount of residual tissues are scraped, the tissues falling into the sealing curette head can be pushed into the inlet of the storage cavity through the movable curette piece; the arc-shaped push rod is pulled to drive the piston plate to move, tissue can be sucked into the storage cavity under the action of negative pressure, the temporary storage effect is achieved, scraped tissue can be taken out easily, and the requirement for frequently replacing instruments or cleaning scraped objects in the operation process is avoided.

The utility model relates to the technical field of intrauterine devices, in particular to a T-shaped intrauterine device external hanging fixator which comprises a fixing portion and an installation portion, the fixing portion comprises a fixing cylinder and a fixing plate arranged at the top of the fixing cylinder, two through hanging holes are oppositely formed in the side wall of the fixing cylinder, and a fixing rod is arranged at the position, corresponding to the axis of the fixing cylinder, of the top of the fixing plate. The fixing rod is spiral; the mounting part comprises a mounting cylinder coaxially and movably arranged on the fixing cylinder in a sleeving mode, the top of the mounting cylinder abuts against the bottom of the fixing plate, and a limiting piece is arranged between the mounting cylinder and the fixing cylinder and used for limiting relative rotation of the mounting cylinder and the fixing cylinder. By adopting the technical scheme provided by the utility model, the technical problem that the expected contraception and treatment effects cannot be achieved due to the fact that the contraception device is easy to move downwards in the uterus and even prolapse from the uterus after the contraception device is put in the uterus in the prior art can be solved.