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172 results about "Pharynx" patented technology

The pharynx (plural: pharynges) is the part of the throat behind the mouth and nasal cavity, and above the esophagus and larynx – the tubes going down to the stomach and the lungs. It is found in vertebrates and invertebrates, though its structure varies across species.

Intelligent monitoring system and method for swallowing rehabilitation

The invention provides an intelligent monitoring system and method for swallowing rehabilitation, and the method comprises the steps: determining the mistaken aspiration risk feature of a pressure peak value in the swallowing rehabilitation through the high-frequency energy sudden change amount of cough sound and the delay feature of a food mass through the pharynx, and when the mistaken aspiration risk feature is greater than a risk threshold value in the swallowing rehabilitation, stopping the swallowing rehabilitation. According to biomechanical information in swallowing rehabilitation, coordination scores of all rehabilitation stages in the swallowing rehabilitation process are determined, and then function recovery indexes of the swallowing function in the pharyngeal period in the swallowing rehabilitation process are determined according to all the coordination scores and mistaken aspiration risk characteristics. The swallowing efficiency index in swallowing rehabilitation is extracted, then the rehabilitation deviation characteristic of the pharynx is determined through the swallowing efficiency index and the function recovery index, and personalized adjustment is conducted on the swallowing rehabilitation scheme after sound-light alarm based on the rehabilitation deviation characteristic. Based on the scheme, personalized coordination of the rehabilitation scheme in swallowing rehabilitation can be realized, so that the recovery efficiency of the swallowing function in the pharyngeal period can be improved.
Owner:THE SECOND XIANGYA HOSPITAL OF CENT SOUTH UNIV

Interface

A user interface comprising a non-sealing nasal cannula and a mask arranged about the nasal cannula, the mask including a seal configured with a user's face to allow the interface to be pressurised, the cannula configured to deliver breathing gases to the nares of a user at a flow rate exceeding the intended user's peak inspiratory flow requirements so that the mask and the user's pharynx are flushed continuously with fresh breathing gases to reduce dead space.
Owner:FISHER & PAYKEL HEALTHCARE LTD

Pharyngeal swab collection device

The invention relates to the technical field of automatic sampling manipulators, and provides throat swab collecting equipment which comprises a shell part, a tongue pressing cylinder, an image vision system, a flexible actuator and a swing arm driving system. The tongue pressing cylinder is detachably arranged at the head end of the shell part; the image vision system is arranged in the shell part and can perform image vision acquisition on the oral cavity when the tongue pressing cylinder is in an open state; the flexible actuator is arranged in the shell part and is used for flexibly clamping the swab; the swing arm driving system is arranged in the shell part and is in transmission connection with the flexible actuator; the swing arm driving system can drive the flexible actuator so as to drive the swab to swing in all directions, rotate around the swab and move front and back relative to the shell part. According to the throat swab collecting equipment, a collected person can complete oral swab collecting work by himself / herself, the collecting process is automatically completed, the collecting process is safe and reliable, the collected person is high in comfort, and the whole process does not need participation of medical staff.
Owner:INNOVATION CENTER OF YANGTZE RIVER DELTA ZHEJIANG UNIVERSITY

Dysphagia rehabilitation training device

The invention discloses a dysphagia rehabilitation training device which is characterized by comprising a base, a control panel, a water tank, a water pump and a training mechanism. The training mechanism comprises a plurality of electric push rods arranged in a lower cavity of an adjusting frame at equal intervals, a plurality of sleeves are arranged in an upper cavity of the adjusting frame at equal intervals, pistons are arranged at the output ends of the electric push rods and slidably mounted in the sleeves, and a supporting rod of an L-shaped structure is fixedly mounted at the top of the adjusting frame. A peristaltic pipe is arranged at the front end of the supporting rod, a stimulation ball is arranged at the front end of the peristaltic pipe, a plurality of air pipes are connected to the interior of the peristaltic pipe, the air pipes are slidably installed in the supporting rod, the tail ends of the air pipes are connected to the top of the sleeve, and a water outlet pipe and a water inlet pipe are arranged at the tail end of the stimulation ball; the water inlet pipe and the water outlet pipe are slidably mounted in the supporting rod; the device can guide the root of the tongue, stimulate the pharynx and train swallowing muscles at the same time.
Owner:THE SECOND AFFILIATED HOSPITAL ARMY MEDICAL UNIV

Method and system for medical endoscopic imaging analysis and manipulation

An endoscopic medical imaging analysis and manipulation method including: capturing endoscopic images of laryngeal, pharyngeal and / or surrounding tissue structures during examination of the larynx, pharynx and / or surrounding tissue using an endoscope, feeding the captured endoscopic images to first and second instances of artificial intelligences, the first instance of artificial intelligence having been trained to identify suspicious areas of laryngeal, pharyngeal and / or surrounding tissue structures showing signs of alterations from healthy laryngeal, pharyngeal and / or surrounding tissue and the second instance of artificial intelligence having been trained to detect and classify abnormalities in the mucosal layer or the tissue of the larynx, pharynx and / or surrounding tissue, overlaying the captured endoscopic images with one or more markings indicating an area or areas indicated by the first instance of artificial intelligence as suspicious, and displaying the overlaid captured endoscopic images on a monitor, together with information provided by the second instance of artificial intelligence.
Owner:OLYMPUS MEDICAL SYST CORP

Particles for nourishing and clearing heat from throat as well as preparation method and application of particles

The invention discloses a throat nourishing and clearing granule as well as a preparation method and application thereof, and belongs to the field of pharmaceutical preparations, the throat nourishing and clearing granule comprises the following components in parts by weight: 10-20 parts of radix rehmanniae recen, 10-20 parts of radix ophiopogonis, 10-20 parts of radix paeoniae alba, 5-15 parts of moutan bark, 5-15 parts of thunberg fritillary bulb, 10-20 parts of radix scrophulariae and 5-15 parts of lily; the preparation method comprises the following steps: S1, preparing raw materials; s2, crushing; s3, mixing; s4, performing granulation; s5, drying; s6, screening to obtain prepared particles; the granules for nourishing and clearing heat from throat provided by the invention can nourish yin and clear heat, remove stasis and relieve sore throat, relieve symptoms such as throat pain, dry mouth and pharynx, throat itching, foreign body sensation of throat and the like, have a good clinical curative effect and few side effects, and are especially suitable for yin deficiency and lung heat patients with chronic pharyngolaryngitis delayed and unhealed, recurrent attack, dry oropharynx, dysphoria in both heart and heart, dry cough without phlegm, less and sticky phlegm and the like.
Owner:THE FIRST HOSPITAL OF HUNAN UNIV OF CHINESE MEDICINE (CLINICAL RES INST OF TRADITIONAL CHINESE MEDICINE)

Cattle and sheep OP liquid collecting device

The utility model relates to the technical field of OP liquid collecting devices, and discloses a cattle and sheep OP liquid collecting device which comprises an injector, a connecting piece detachably installed on a needle cylinder, a flexible pipe detachably installed on the connecting piece and an OP liquid collecting part detachably installed on the flexible pipe. The OP liquid collecting part can extend into the pharynx or throat of cattle and sheep through the flexible pipe; the OP liquid collecting part comprises an OP liquid collecting head, and the OP liquid collecting part can suck mucus at the pharynx or the throat of cattle and sheep through the collecting cavity; the OP liquid collecting part further comprises a flexible sampling part, the flexible sampling part is arranged on the OP liquid collecting head, and when the OP liquid collecting part extends into the pharynx or throat of cattle and sheep, the OP liquid collecting part can also adhere to mucus through the flexible sampling part. According to the mucus collecting device, in the mucus collecting process of the OP liquid collecting component, the pharynx or the throat or the tongue root of cattle and sheep cannot be damaged, and the collecting process is convenient and rapid.
Owner:QINGHAI ANIMAL DISEASE PREVENTION & CONTROL CENT

Method and system for medical endoscopic imaging analysis and manipulation

An endoscopic medical imaging analysis and manipulation method comprising: Capturing endoscopic images of laryngeal or pharyngeal tissue structures during examination of the larynx using an endoscope inserted through a patient's nose or mouth, Feeding the captured endoscopic images to two instances of artificial intelligences, a first of which having been trained to identify suspicious areas of laryngeal or pharyngeal tissue structures showing signs of alterations from healthy laryngeal or pharyngeal tissue and a second of which having been trained to detect and classify abnormalities in the mucosal layer or the tissue of the larynx or pharynx, Overlaying the captured endoscopic images with one or more markings indicating an area or areas indicated by the first instance of artificial intelligence as suspicious, and Displaying the overlaid captured endoscopic images on a monitor, together with information provided by the second instance of artificial intelligence.
Owner:OLYMPUS MEDICAL SYST CORP

Device for laryngectomised persons

PCT designated stageWO2025242936A1Tracheal tubesTracheaePharynxBiocompatibility
The invention relates to a device (100) for laryngectomised persons, comprising a respiratory prosthesis (120) comprising an adapted tube (122) for connecting to a new incision that is made in the neck and extends to the pharynx at the base of the tongue, and comprising at least one biocompatible membrane (124) for filtering liquids and solids and preventing them from passing through the tube (122), wherein a coupler (126) for coupling to the new incision is connected internally to the distal end of the tube (122) and externally to at least one pipe (130a, 130b) for exterior communication with a tracheostoma coupler (110), which comprises a sealingly and detachably accommodated HME filter (112), such that the new-incision coupler (126) is connected to the tracheostoma coupler (110).
Owner:YSIUM MEDICAL SL

Endoscopic imaging manipulation method and system

The present disclosure concerns an endoscopic imaging manipulation method and system. The method comprises capturing endoscopic images of laryngeal and / or pharyngeal tissue structures during examination of the larynx and / or pharynx using an endoscope inserted through a patient's nose or mouth, feeding the captured endoscopic images to an instance of an artificial intelligence trained to identify suspicious areas of laryngeal and / or pharyngeal tissue structures showing signs of alterations from healthy laryngeal and / or pharyngeal tissue, overlaying the captured endoscopic images with a marking indicating areas indicated by the instance of artificial intelligence as suspicious, and displaying the overlayed captured endoscopic images on a monitor.
Owner:OLYMPUS MEDICAL SYST CORP

Pharynx aspiration device for minimizing infectious particle exposure during endonasal surgeries

A method for minimizing infectious particle exposure during endonasal surgeries includes the steps of: introducing an aspiration device through a mouth of a patient and positioning a distal tip within the nasopharynx space, the aspiration device comprising an elongated balloon catheter having an inflatable balloon located within a distal region thereof and a distal aspiration port that is positioned distal to the balloon; inflating the balloon so that the balloon occupies the nasopharynx space; and aspirating any infectious particles within the nasopharynx space via the distal aspiration port.
Owner:MT SINAI SCHOOL OF MEDICINE

Endoscopy device having an enhanced flexible shaft enabling patient comfort zone and distal semi-flexible shaft enabling functional endoscopic zone

Systems and methods are disclosed for an endoscope for use in a surgical procedure, e.g., a pediatric trans-nasal endoscopy procedure. The endoscope may include a handle for gripping by a user, and a shaft extending from the handle. The shaft may have a working channel extending longitudinally therethrough. When the shaft is in a fully-inserted position, the shaft may have an extracorporeal zone configured to reside proximal relative to the patient's nasal opening, a patient comfort zone configured to reside from the patient's nose through the patient's pharynx and to a top of the patient's esophagus, and a distal functional endoscopic zone configured to reside from the top of the patient's esophagus to a distalmost tip of the shaft. The patient comfort zone has a relatively higher flexibility so as to maximize patient comfort for that portion of the shaft that is maintained in the curvatures of a patient's nasal cavity during a surgical procedure.
Owner:EVOENDO INC

Nasopharyngolaryngoscope

ActiveCN309400165SLarynxNose
1. Name of the design product: Nasopharyngolaryngoscope. 2. Use of the design product: For medical units to conduct examinations and treatments on the mouth, nose, pharynx, and larynx in clinical practice, and to be used in conjunction with equipment such as electronic endoscope image processors. 3. Design key points of the design product: Lies in the shape. 4. Picture or photo that best shows the design key points: Perspective view 1.
Owner:MACROLUX MEDICAL TECH CO LTD

Disposable oropharyngeal airway device

The utility model discloses a disposable oropharyngeal airway device, and mainly relates to the technical field of medical instruments. Comprising a protective plate, a round hole is formed in the side face of the protective plate, a communicating pipe is fixedly connected to one side of the protective plate, the communicating pipe is communicated with the round hole, a sealing structure is arranged on one side of the protective plate and comprises a lead screw, the section of the lead screw is in a T shape, and the lead screw is in threaded connection with the protective plate. The end, close to the communicating pipe, of the lead screw is rotationally connected with a connecting ring, the side, away from the lead screw, of the connecting ring is fixedly connected with a rubber cover, two side holes are formed in the side face of the protection plate, and an elastic rope penetrates through the inner walls of the side holes in a sliding mode. The disposable oropharynx airway device has the advantages that the tongue can be prevented from falling backwards, sputum can be sucked, the airway can be simply opened, and when the disposable oropharynx airway device is used, the rubber cover can be conveniently adjusted to receive saliva, so that the saliva is prevented from leaking to pollute the surrounding environment.
Owner:THE 951ST ARMY HOSPITAL OF THE CHINESE PEOPLES LIBERATION ARMY

Laryngoscope operation training method and device based on sensor intelligent feedback

The invention relates to the technical field of medical teaching aids, and discloses a laryngoscope operation training method and device based on sensor intelligent feedback, and the method comprises the steps: reconstructing a human body oral cavity simulation model for training, simulating anatomical mechanical gradients including a tongue body, a pharynx and teeth, and obtaining a simulated model; burying pressure sensors with different precisions under the skin of each key part in the simulation model according to the anatomical mechanics of the part; the oral cavity simulation model is connected to carry out laryngoscope operation training, signals of all the pressure sensors are collected in real time and converted into digital signals, key parameters of the pressure signals are obtained through calculation after analysis and processing so as to judge the contact state, and corresponding acousto-optic feedback and alarm are automatically triggered according to the contact position and the contact state. An intelligent sensing network with biomechanical simulation capability is constructed, the contact strength in a laryngoscope operation path is evaluated through a multi-level pressure monitoring and dynamic feedback mechanism, and a quantitative evaluation system of operation quality is established.
Owner:EYE & ENT HOSPITAL SHANGHAI MEDICAL SCHOOL FUDAN UNIV

Stimulation device for swallowing training

The invention relates to the technical field of rehabilitation treatment, in particular to a stimulation device for swallowing training. The stimulation device for swallowing training comprises a gun-shaped shell, and a gun barrel is arranged on the front portion of the gun-shaped shell; the front end, far away from the gun-shaped shell, of the gun barrel is connected with the massage head; the liquid storage tank is detachably arranged in the middle of the lower side of the gun-shaped shell; the liquid pumping box is arranged in the middle of the inner side of the gun-shaped shell; and the vertically downward electric push rod is arranged at the top of the inner side of the gun-shaped shell. According to the device, the pharynx of a user is stimulated through three different modes of massaging by the massage head, contacting with clear water at different temperatures and enabling the clear water to have sour taste, the swallowing reflex sensitivity is enhanced by virtue of the combined action, and the injected clear water is pumped into the mouth of the user through the up-down movement of the piston plate in the liquid pumping box, so that the swallowing reflex sensitivity is enhanced. The injection amount can be conveniently controlled, and cough or vomiting reaction caused by discomfort of a user due to overstimulation can be avoided.
Owner:FIRST AFFILIATED HOSPITAL OF XINJIANG MEDICAL UNIVERSITY

Atomization device suitable for coma patient

The atomization device suitable for the coma patient comprises an atomizer, a conversion connecting pipe and a ventilation pipeline, the atomizer comprises an output connecting pipe, and the output connecting pipe is detachably connected with an internal thread in the conversion connecting pipe in a clamped mode through an external thread formed in the outer wall of the output connecting pipe. The bite block and the outlet end of the atomizer are connected in a spiral tightening manner, so that the atomizer is convenient to connect and remove, and the burden of nurses is relieved; the ventilation pipeline comprises an oropharynx pipeline, a tooth cushion and a connecting pipe which are integrally formed, the connecting pipe is used for detachably connecting the ventilation pipeline and the conversion connecting pipe in an inserted mode, when a patient uses the ventilation pipeline, the oropharynx pipeline can stretch into the throat and abut against and is fixed through the tooth cushion, medicine sent out by the atomizer directly reaches the pharynx, and the medicine can be conveniently used by the coma patient; meanwhile, the problems that the amount of gas inhaled by a patient is small, and the medicine is not fully utilized can be solved.
Owner:TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH

Gastroesophagus and throat multichannel pH synchronous monitoring system and method

ActiveCN120919490AMedical devicesCatheterUpper esophageal segmentLower esophagus
The invention provides a multi-channel pH synchronous monitoring system and method for gastroesophagus and throat. The system comprises a flexible catheter which is used for being inserted into a monitoring part through a nasal cavity; the plurality of pH sensors are integrated on the flexible catheter and are respectively used for monitoring the pH values of the throat part, the upper section of the esophagus and the lower section of the esophagus; the signal collector is connected with the near end of the flexible catheter and is used for synchronously collecting data of the plurality of pH sensors; and the analysis module is used for judging a reflux path and performing diagnosis according to the time sequence and amplitude of the data change of the plurality of pH sensors. The multiple pH sensors are integrated on the single flexible catheter to monitor the pH values of multiple parts at the same time, the signal collector is used for synchronously collecting the pH data, gastroesophageal-throat multichannel pH synchronous monitoring is achieved, reflux path judgment and reflux diagnosis are conducted based on the synchronous monitoring data, and the reflux diagnosis accuracy is improved.
Owner:RESTECH (LANGFANG LINKONG FREE TRADE ZONE) INTELLIGENT TECHNOLOGY CO LTD

Ice bag for the pharynx

ActiveCN224403859UPrevention of Postoperative BleedingSolve hard-to-fix puzzlesStructural engineeringPharynx
The utility model provides a pharyngeal ice bag, which comprises a middle ice bag containing sleeve bag, which is a rectangular open-top pocket structure, an ice bag is placed in the middle ice bag containing sleeve bag, the inner part of the ice bag is divided into multiple small compartments, each small compartment contains a polymer gel, and a set of elastic fixing belts, which comprises two pairs of elastic connecting belts arranged on both sides of the middle ice bag containing sleeve bag, the outer surface of the left strap of each pair of elastic connecting belts is provided with a Velcro surface, and the inner surface of the right strap is provided with a Velcro hook surface matched with the Velcro surface. The utility model has the advantages that it is used for preventing postoperative hemorrhage of the pharynx and relieving postoperative pain of patients. The utility model solves the problem that the pharyngeal ice bag is not easy to fix, and the method is simple and practical.
Owner:JINGMEN HOSPITAL OF TRADITIONAL CHINESE MEDICINE

Gastrointestinal decompression tube and bed body fixing device

The utility model discloses a gastrointestinal decompression tube and bed body fixing device, and relates to the technical field of gastrointestinal decompression tube fixing. The angle adjusting device comprises a fixing block of a U-shaped structure, the bottom of the fixing block is in threaded connection with a first bolt, an anti-skid pad is fixedly installed at the end, located in the fixing block, of the first bolt, a rotating assembly with an angle adjusting function is arranged at the top of the fixing block, and a connecting rod is arranged on the rotating assembly. One section of the gastrointestinal decompression tube is placed in the arc-shaped rod, meanwhile, the gastrointestinal decompression tube placed in the arc-shaped rod is bound and fixed through the hook-and-loop fasteners, when a patient needs to turn over or sit, the connecting rod is rotated to a proper angle in advance, then the connecting rod is fixed to the current angle through the rotating assembly, and the gastrointestinal decompression tube is fixed to the arc-shaped rod through the hook-and-loop fasteners. Meanwhile, the telescopic rod assembly stretches out and draws back to drive the arc-shaped rod to move to a proper position, so that the gastrointestinal decompression tube arranged in the arc-shaped rod is close to the body side of the patient, and the situation that the gastrointestinal decompression tube is heavily dragged to stimulate the pharynx is avoided.
Owner:HANGZHOU LINPING DISTRICT TRADITIONAL CHINESE MEDICINE HOSPITAL

Electronic laryngoscope

ActiveCN309661543SVideo laryngoscopeLarynx
1. The name of the design product: electronic laryngoscope. 2. The use of the design product: for checking the lesions of pharynx and larynx. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: perspective view.
Owner:吴秀荣

Oral cavity attachment tool and halitosis measurement system

A mouth cavity attachment tool (1A) is attachable to a mouth cavity (M) of a person (P) under examination. The mouth cavity attachment tool (1A) includes a partitioning portion (10A) and a gap forming portion (11A). The partitioning portion (10A) partitions a mouth cavity (M) into a first portion (M1) where objects of measurement of halitosis are located and a second portion (M2) communicating with a pharynx (6) of the person (P) under examination. The gap forming portion (11A) is connected to the partitioning portion (10A) and forms gaps (G) in spaces to the objects of measurement. Since the mouth cavity attachment tool (1A) includes the partitioning portion (10A) partitioning the mouth cavity (M) into a first portion (M1) where tooth rows (2) and gums (3) are located and a second portion (M2) communicating with the pharynx (6) of the person (P) under examination, halitosis can be detected accurately.
Owner:I PEX INC

Shield with a mirror for oral observation

ActiveJP1802094SPharynxDentistry
As shown in the "Reference Diagram Showing the Usage State", this article is attached to a penlight and is used when an observer (such as a doctor) observes the oral cavity of an observed person (such as a patient). This article is composed of a transparent shield plate provided with a mirror and a light holder. The mirror is provided inclined with respect to the shield plate by a mirror holder. The mirror surface of the mirror is arranged on the front side. A through hole is formed in the shield plate, and the light holder is fixed to this through hole. The light holder is formed from an elastic material. The tip of the penlight can be fitted into and held in the hole of the light holder. Since the shield plate is transparent, the observer can observe the oral cavity of the observed person through the shield plate. By the shield of this article, the observer is prevented from being splashed by droplets from the oral cavity of the observed person, while the observed person can confirm the state of their pharynx by the mirror.
Owner:医療法人こんの小児科クリニック

Pneumonic genome detection system and method based on throat swab sample

The invention relates to the technical field of molecular biology, in particular to a pneumonia genome detection system and method based on a throat swab sample. The method comprises the following steps: obtaining a pharynx throat swab sample solution, and adding lysozyme for sample digestion to obtain a sterile throat swab sample; the method comprises the following steps: putting a sterile throat swab sample into a nucleic acid extraction kit, and carrying out nucleic acid quality screening treatment on the sterile throat swab sample to obtain a sterile throat swab nucleic acid high-quality sample; the method comprises the following steps: obtaining a pneumonia related pathogen historical genome sequence, and carrying out related pathogen primer design and PCR amplification library construction to obtain a throat swab nucleic acid PCR amplification sequence library; and performing high-throughput sequencing treatment and genomic sequence pathogen comparison detection on each group of throat swab nucleic acid pneumonia gene sequences in the throat swab nucleic acid PCR amplification sequence library to obtain a throat swab sample pneumonia pathogen genome detection result. According to the invention, accurate identification and quantitative analysis of pneumonia pathogens can be realized.
Owner:GUANGZHOU LANWEI MEDICAL LAB CO LTD

Positioning device for edentulous jaw oral implantation

The invention discloses a positioning device for edentulous jaw oral implantation, and relates to the technical field of oral implantation, the main points of the technical scheme are that the positioning device comprises a support frame, the upper surface of the support frame is slidably connected with a support rod, and the positioning device also comprises an upper positioning plate and a lower positioning plate; the upper positioning plate and the lower positioning plate are arc-shaped, the end parts of the upper positioning plate and the lower positioning plate are rotationally connected, and operation holes are formed in the upper positioning plate and the lower positioning plate; a control rope is rotationally connected to the side wall of the upper positioning plate, and one end of the control rope is fixedly connected to the upper end of the supporting rod; a pull rope is fixedly connected to the side wall of the lower positioning plate, and one end of the pull rope is arranged at the end of the supporting frame. The invention has the advantages that the flushing fluid can be effectively prevented from flowing into the oral cavity of a patient and flowing into the esophagus or trachea through the pharynx of the patient, the patient is prevented from swallowing the flushing fluid into the abdomen, the body health of the patient is guaranteed, and convenience is brought to medical personnel and the patient.
Owner:SHAOXING DENTAL HOSPITAL

Composition for inflammatory diseases of the mouth and throat

Composition, in particular pharmaceutical composition, in the form of a fixed dosage (solid dosage form) for sucking and / or chewing, preferably for sucking, in particular lozenge, preferably for use in the prophylactic and / or therapeutic topical (local) treatment of inflammatory diseases of the mouth and throat, wherein the composition contains an effective, in particular pharmaceutically and / or therapeutically effective, amount of an active ingredient preferably suitable and / or effective for the topical (local) treatment of inflammatory diseases of the mouth and throat, in particular with antiseptic and / or antimicrobial properties, preferably with antibacterial and / or antiviral and / or antifungal properties, wherein the active ingredient is incorporated and / or embedded in a solid matrix, wherein the composition, in particular the solid dosage form and / or the matrix, releases the active ingredient upon topical (local) application and / or use, preferably by sucking and / or chewing, preferably by sucking, in the oral and pharyngeal cavity; wherein the active ingredient is octenidine, in particular in the form of a pharmaceutically compatible and / or physiologically acceptable salt or ester, preferably in the form of a pharmaceutically compatible and / or physiologically acceptable salt, particularly preferably octenidine dihydrochloride; and wherein the composition, in particular the solid dosage form and / or the matrix, furthermore and / or additionally contains at least one further ingredient (a) and / or (b), in particular (a) and (b), wherein the at least one further ingredient (a) and / or (b) is selected from the group of (a) Flavor modulators, in particular selected from the group of the following components (i), (ii) and / or (iii): (i) Bitter (taste) masking agents, in particular selected from the group consisting of bitter taste receptor antagonists, preferably 4-(2,2,3-trimethylcyclopentyl)butanoic acid, and saponins, preferably glycyrrhizic acid (glycyrrhizin) and its salts or esters and / or glycyrrhetinic acid (glycyrrhetin) and its salts or esters, complexing agents, in particular cyclodextrins, and combinations or mixtures thereof, (ii) Bitter substances, in particular coffee extract and / or tea extract and / or their respective bitter substances, preferably coffee extract and / or its bitter substances, (iii) preferably natural or nature-identical (aroma) oils and / or essential oils, in particular with antiseptic and / or antimicrobial properties, preferably with antibacterial, antifungal and / or antiviral properties, in particular selected from the group of anise oils, in particular star anise oil, peppermint oil, eucalyptus oil, lavender oil, tea tree oil, chamomile oil, clove oil, rosemary oil, caraway oil, cinnamon oil, sage oil and fennel oil, as well as combinations or mixtures thereof; in particular wherein the ingredient (a) and / or the flavor modulator comprises a combination of at least two different components (i), (ii) and / or (iii), preferably a combination of components (i), (ii) and (iii); (b) Acidulants, in particular saliva-stimulating and / or flavor-enhancing acidulants, preferably acidulants authorized under pharmaceutical and / or food law and / or acidulants authorized as pharmaceutical additives and / or food additives, in particular selected from the group of tartaric acid and its salts, in particular sodium tartrate, sodium potassium tartrate (Rochelle salt) and calcium tartrate, citric acid and its salts, metatartaric acid, fumaric acid, ascorbic acid, phosphoric acid and its salts, stannous chloride, in particular tin(II) chloride, malic acid, lactic acid, adipic acid, succinic acid and other pharmaceutically compatible and / or physiologically acceptable organic acids and their salts, as well as their combinations or mixtures.
Owner:MARIA CLEMENTINE MARTIN KLOSTERFRAU VERTRIEB GESELLSCHAFT MBH

A method for preparing a rat acute pharyngitis model

ActiveCN118765861BAccessory food factorsAcute PharyngitisPharynx
The present research aims to successfully establish a rat acute pharyngitis model, and to observe the pathological changes of the pharynx of the animal and detect the pharynx and blood related indexes to evaluate the stability of the model, so as to make a rat acute pharyngitis model which is simple to operate, long in symptom maintenance time, stable and unified, more close to the clinic, and to facilitate the further research on the pathogenesis and pathophysiological changes of the acute pharyngitis model, and to provide a certain basis for how to implement the pharynx protection intervention measures. The method for constructing the rat acute pharyngitis model of the present application is simple to operate, long in symptom maintenance time, stable and unified, more close to the clinic, and good in stability and repeatability. The rat acute pharyngitis model constructed by the present application is not only simple to operate, but also long in symptom maintenance time, which can be up to more than 1 month.
Owner:河南省儿童医院郑州儿童医院

Treatment of nasal cavity inflammation and mucus hypersecretion

PCT designated stageWO2026049833A1Dispersion deliveryEnemata/irrigatorsMucous secretionPharmacology
The present application relates to treatment of nasal cavity inflammation and mucus hypersecretion. One aspect of the present invention is a method of treatment of rhinitis and rhinosinusitis, wherein the treatment reduces nasal stuffiness, nasal congestion, and phlegm secretion. Reduction of phlegm secretion from the nasal cavity into the pharynx can also reduce cough frequency from infectious and allergic rhinitis. In the preferred embodiment, FEMA 4557, is an example of a molecule, topically applied to the nasal mucosa, that can be used to treat rhinitis. FEMA 4557 is a potent non-irritating suppressor of acute inflammation in the nasal cavity and sinuses, a property not previously described for other topical cooling agents. Thus, FEMA 4557 and related analogs may have therapeutic utility for treating nasal inflammation and mucus hypersecretion.
Owner:WEI EDDIE