25 results about "Momordica" patented technology

The invention provides a fat-reducing composition based on an agaricus bisporus extract as well as a preparation method and application of the fat-reducing composition, and belongs to the technical field of nutrition and health care. The fat-reducing composition comprises the following raw materials in parts by weight: 10-30 parts of an agaricus bisporus extract, 5-15 parts of a green tea extract, 5-15 parts of bitter gourd peptide, 3-10 parts of seaweed meal and 10-30 parts of resistant dextrin. The agaricus bisporus extract disclosed by the invention can regulate intestinal flora and promote fat metabolism; tea polyphenol in the green tea extract can inhibit fat synthesis and promote fat oxidation; momordica charantia peptide has an obvious hypoglycemic effect; the seaweed meal (containing fucoxanthin) has the effects of burning fat cells and eliminating fat accumulation; the resistant dextrin is used as dietary fiber, so that satiety is increased, and caloric intake is reduced. The raw materials cooperate with each other, so that the composition has better fat-reducing and weight-reducing effects, and the total cholesterol and triglyceride levels are reduced.

The invention discloses a composite combined preparation for synergistically treating and conditioning diabetes, relates to the technical field of foods, health foods or dietary supplements for adjuvant therapy and health care of diabetes, and in particular relates to a composite combined preparation for synergistically treating and conditioning diabetes. The preparation comprises albumin peptide, saussurea involucrata culture, vitamin B1, vitamin B2, wheat oligopeptide, corn oligopeptide, collagen peptide, mulberry leaf extract, rhizoma polygonati extract, sea-buckthorn extract, isomaltitol, maltodextrin, ginseng extract and bitter gourd extract. Through the synergistic effect of all the components, comprehensive auxiliary conditioning on diabetes is realized from multiple targets of maintaining colloid osmotic pressure and nutrition, regulating glycolipid metabolism in multiple ways, protecting pancreatic beta cell functions, enhancing insulin sensitivity, preventing nerve and blood vessel complications, meeting special diet requirements and the like. The composition can be prepared into food, health-care food or dietary supplement and other dosage forms.

The invention discloses chrysanthemum, siraitia grosvenorii and camellia flavored tea jelly and a preparation method thereof. The snow pear and chrysanthemum bud tea consists of the following components in parts by weight: 30-40 parts of snow pear slices, 15-16 parts of chrysanthemum buds, 32-36 parts of siraitia grosvenorii blocks, 10 parts of seafloor dried coconut stuffing, 15 parts of dried lily bulbs, 17-20 parts of dried bamboo sugarcanes, 4-7 parts of dried water chestnuts, 3 parts of red Chinese wolfberry fruits, 120-150 parts of fresh snow pears, 22-24 parts of brown crystal sugar, 20 parts of camellia Guanyin tea and 7 parts of golden chrysanthemum petals. The invention relates to a food formula and a food production process, and relates to a food formula and a food production process. Food materials such as chrysanthemum buds and momordica grosvenori in the ingredients have the effects of clearing heat, moistening the lung, relieving sore-throat, promoting salivation and the like, the requirements of current consumers for healthy health-preserving foods are met, and the konjac jelly powder is mainly prepared from glucomannan, is low in calorie and rich in dietary fiber, can increase satiety, promote intestinal peristalsis and improve the health-preserving effect. And the demand that people do not want to take too much heat while enjoying delicious food is met.

The application provides a momordica root polysaccharide and a preparation method and application thereof, and belongs to the technical field of natural product development. The preparation method of the momordica root polysaccharide comprises the following steps: drying and crushing momordica roots, and removing fat by ethanol reflux; after water extraction and alcohol precipitation, and removing protein, a momordica root crude polysaccharide is obtained; and the momordica root crude polysaccharide is sequentially separated and purified by DEAE-52 cellulose column and Sephadex LH20 gel column to obtain the momordica root refined polysaccharide. The preparation method has the advantages that the polysaccharide obtained by directly extracting water in the prior art has a narrow molecular weight distribution range and better immune enhancement activity. Experimental results show that the momordica root polysaccharide can stimulate RAW264.7 cells to secrete NO, TNF-alpha and IL-6 factors, enhance the phagocytosis of RAW264.7 cells, and thus enhance the cell immune function, and can be applied to the development of products for improving immunity.

In one aspect, the disclosure relates to immunogenic compositions comprising a semisynthetic saponin adjuvant (VSA) including, but not limited to, VSA-1 and VSA-2, derived from a Momordica saponin and at least one antigen. In a further aspect, the immunogenic compositions can include other known adjuvants, emulsifiers, and / or surface-active agents and can be formulated as liposomes, micelles, emulsions, and the like. Also disclosed are methods of eliciting effective immune responses to viral, bacterial, protozoal, and neoplastic diseases using the disclosed immunogenic compositions.

The invention discloses a preparation method of a medicinal and edible plant composition with a synergistic hypoglycemic effect, and relates to the technical field of preparation of medicinal and edible health products. The method comprises the following steps: step a, crushing jerusalem artichoke, bitter gourd and Chinese waxgourd peel according to a mass ratio of 1: (0.5-2): (0.5-1.5) until the particle size is 0.2-0.5 mm, performing cold soaking at 4-10 DEG C for 48-72 hours, and performing filtering to obtain a water-soluble component filtrate; step b, adding cellulase (the enzyme activity is greater than or equal to 10000 U / g) which accounts for 0.1-0.3% of the mass of the raw materials into the residues in the step a; according to the method, multi-process combined extraction is carried out, specifically, heat-sensitive components such as momordica saponins are reserved through cold extraction (4-10 DEG C), fat-soluble components are extracted through supercritical extraction, cell membranes are damaged through high-temperature transduction to release cinnamyl aldehyde, the synanthrin decomposition rate reaches 75% through the enzymolysis technology, the quercetin conversion rate is larger than or equal to 90%, and the quercetin content is larger than or equal to 30% through the enzymolysis technology. According to the invention, four mechanisms, namely alpha-glycosidase inhibition, insulin sensitization, oxidation resistance and GLUT4 transport promotion, are used for synergistically reducing blood glucose, the blood glucose reducing effect is remarkable, the absorption rate of fat-soluble components is increased by 2 times by the nano-emulsion, and the in-vivo half-life period of the balsam pear saponin is prolonged to 6.5 hours by the lipidosome.

The invention discloses application of a CAPS molecular marker in identification of bitter gourd pulp thickness. It is found through analysis that compared with a thick-pulp bitter gourd variety, the 12132249th site of the No.6 chromosome of the thin-pulp bitter gourd mutant M17 contains insertion of six basic groups (AGTGAA). A specific primer is designed aiming at the mutation site, a bitter gourd genome is amplified by utilizing the primer, a PCR amplification product is subjected to incision enzyme PciI enzyme digestion, and bitter gourd varieties with thick pulp characters and thin pulp characters can be identified according to the size of an enzyme digestion product. The method can accurately identify the pulp thickness in the early growth stage of the bitter gourd, improves the breeding efficiency of the bitter gourd variety with thick pulp, and has the advantages of high efficiency, accuracy, simplicity and convenience in operation and the like.

The application discloses application of a Chinese medicine pair effective component composition of Astragalus membranaceus and Curcuma zedoary in preparation of anti-tumor metastasis drugs. The composition is composed of calycosin-7-glucoside and curcumin. The composition can effectively inhibit transendothelial invasion and vasculogenic mimicry generation of tumor cells at a non-toxic dose, and has the advantages of high efficiency and low toxicity in treating tumor metastasis. The important point of the application is that the preferred composition can significantly reduce the exosome LAP-TGF-beta1 protein loading level, thereby greatly inhibiting the tumor metastasis process caused by the exosome-mediated TGF-beta signal pathway. The finding provides a new perspective for the development of drugs for targeting exosome LAP-TGF-beta1 protein loading to resist tumor metastasis, and overcomes the defects of unclear effective components, uncontrollable proportioning and unclear treatment effect of traditional Chinese medicine compatibility. Therefore, the Chinese medicine effective component composition has application prospects in preparation of anti-tumor metastasis drugs.

The application discloses a long-chain non-coding RNA of Candida albicans for epigenetically regulating fluconazole resistance and application thereof, belongs to the technical field of biological medicines, and relates to antifungal medicines. The long-chain non-coding RNA for epigenetically regulating fluconazole resistance comprises three nucleotide sequences shown in SEQ ID NO. 1-3. The application further provides application of Momordica charantia protein MAP30 in inhibiting expression of the long-chain non-coding RNA of the Candida albicans genome. The application provides nucleotide sequencing of the long-chain non-coding RNA of the Candida albicans genome for epigenetically regulating fluconazole resistance, open reading frame (ORF) alignment, positioning of the lncRNA on a chromosome, inhibition of lncRNA expression by using the Momordica charantia protein MAP30, and realization of reversing fluconazole resistance, which provides a theoretical basis for revealing the Candida albicans resistance mechanism, developing new antifungal medicines and treatment strategies.

The invention belongs to the field of vegetable molecular technology breeding, and particularly relates to a method for analyzing germplasm genetic diversity and constructing a fingerprint spectrum of balsam pear based on a simple sequence repeat (SSR) marker. By screening high-polymorphism SSR core markers, genetic diversity analysis is carried out on 26 germplasm parts of the balsam pear, and an SSR molecular fingerprint spectrum is constructed. Core SSR markers (MC0569594, MC0450530, MC0687314 and MC10146038) are used for carrying out PCR (Polymerase Chain Reaction) amplification and banding pattern analysis, the polymorphism information content (PIC) is calculated, and the germplasm of the balsam pear is clustered into three main groups through clustering analysis. By combining a fingerprint database, efficient identification and information storage of germplasm of the balsam pear are realized. The method is easy and convenient to operate and high in accuracy, and important technical support is provided for protection, utilization and breeding of germplasm resources of the balsam pear. By means of the method, the variety of the large-top bitter gourds on the market can be rapidly identified, materials with excellent characters can be effectively screened out in the breeding process, the breeding efficiency is improved, and the method has wide application prospects.

The application discloses a kind of based on YOLO series model and confidence threshold determination Defect Momordica fruit recognition method and system belong to agricultural product processing target detection field.This method includes: collecting Momordica fruit multi-view image;It is preprocessed by size normalization, brightness adjustment, noise suppression etc.;Input YOLO series model outputs whole fruit detection frame, good / bad class and confidence;Final determination is completed by non-maximum suppression and confidence threshold;Output result is used for display, storage or drive sorting.System is composed of image acquisition, image preprocessing, YOLO identification, confidence threshold determination, result output module.This application covers a variety of surface defects, reduces environmental and texture interference, outputs stable determination signal, can be directly connected to automatic sorting equipment, with high precision, strong adaptability, deployment flexible etc.Advantages, suitable for Momordica fruit large-scale processing quality detection and grading.

The invention discloses a rapid collection method of siraitia grosvenorii pollen, which comprises the following steps: collecting and treating male flowers, eluting pollen, performing vacuum suction filtration, and drying and storing the pollen, and is different from the prior art: eluting the siraitia grosvenorii pollen from anther by using a sucrose solution; and carrying out two processes of vacuum filtration and normal-temperature air drying to quickly obtain pure and dry pollen with germination power. The bottleneck problems of slow pollen collection speed, fast pollen viability decline, low pollination success rate, small fruits and the like in spray pollination of momordica grosvenori in the prior art are solved, and application results show that the collected pollen is not only suitable for spray pollination of momordica grosvenori, but also good in pollination effect, low in cost and suitable for industrial production. Compared with traditional artificial flower pollination, the method has obvious advantages. The method is easy to master, low in operation difficulty and particularly suitable for being popularized and applied to a large-scale momordica grosvenori orchard.

1. Name of the designed product: packing box (bitter gourd chromium yeast). 2. Use of the designed product: the designed product is used for packing of medicine or food. 3. Design points of the designed product: combination of shape and pattern. 4. Picture or photo showing the design points: front view.

The invention discloses an external traditional Chinese medicine ointment for treating thyroid nodules as well as a preparation method and application thereof, and relates to the field of medicines. The external traditional Chinese medicine ointment comprises traditional Chinese medicine micro powder and a matrix, wherein the traditional Chinese medicine micro powder comprises nidus vespae, dung beetle, cowherb seed, garden balsam seed, ephedra, ground beetle, radix ranunculi ternati, prepared arisaema consanguineum schott, semen momordicae, leech, curcuma zedoary, borneol and selfheal. According to the traditional Chinese medicine micro powder, various insect medicines contain components such as chitinase or enzyme, fiber tissue or cyst can be degraded, targeted knot breaking can be achieved, various plant medicines contain volatile oil or alkaloid components, blood circulation can be improved, and nodule absorption can be promoted. Meanwhile, borneol and ephedra are used for enhancing transdermal absorption of drugs, a matrix promotes drug release, the ointment can directly act on a thyroid nodule focus area, the bioavailability is high, the treatment effect of removing stasis is improved, the burden of liver and kidney is reduced through external administration, skin irritation is small, safety is high, and operation is easy and convenient.

1. Name of the designed product: packaging box (reishi momordica charantia chrysanthemum tea). 2. Use of the designed product: used for product outer packaging. 3. Design points of the designed product: in the shape of the product, pattern and their combination. 4. Picture or photo that best indicates the design points: perspective view.

The invention relates to the technical field of bitter gourd breeding, in particular to a new variety breeding method for increasing the yield of bitter gourds. According to the technical scheme, the new variety breeding method for increasing the yield of bitter gourds comprises the following specific steps: step 1, establishing a bitter gourd multi-omics database; 2, establishing a quality component dynamic monitoring platform; step 3, constructing a'source-library-flow 'collaborative evaluation system; 4, developing a reproductive development efficiency early prediction system; 5, establishing a whole genome selection prediction model; step 6, adopting a CRISPR / Cas9 gene editing technology; 7, integrating a rapid breeding technology; 8, a matched cultivation management system is established, and synchronous optimization of yield and nutritional quality in the breeding process is ensured by integrating genome, transcriptome and metabolome data and performing quantitative analysis on active ingredients such as momordica saponin, polypeptide-P and vitamin C in combination with a high performance liquid chromatography-mass spectrometry technology.

The invention belongs to the technical field of molecular breeding of vegetables, and particularly relates to an InDel molecular marker co-segregated with the length of a fruit stem of a bitter gourd and application of the InDel molecular marker. The mutation site of the InDel molecular marker co-separated from the length of the fruit stem of the bitter gourd corresponds to the insertion / deletion of TTTTAAAAAAT at the 14693294bp on the No.3 chromosome of a bitter gourd genome, and the polymorphism of the base at the site affects the length of the fruit stem of the bitter gourd. The invention also provides a primer pair, a kit and the like for identifying the InDel molecular marker, which can be used for molecular marker-assisted selective breeding of the length of the fruit stem of the bitter gourd, improve the efficiency of genetic improvement of the length of the fruit stem of commercial fruit of the bitter gourd, shorten the breeding period and reduce the breeding cost, and has a wide application prospect in practice of the length of the fruit stem of the bitter gourd.

The application discloses a SNP marker linked with Momordica charantia resistance to Meloidogyne enterolobii and application. The application finds that a SNP site (G / A) exists at 2122 bases of a coding region of a SEC8 gene of Momordica charantia, and the specific position is Chr4-25401664, through identification of Meloidogyne enterolobii of 192 Momordica charantia germplasms collected from all over the world and whole genome association analysis. The resistance of the tested Momordica charantia sample to Meloidogyne enterolobii is determined by designing primers to amplify and detect bands. The application can quickly and accurately analyze the resistance of different Momordica charantia germplasms to Meloidogyne enterolobii, and accelerates application of a molecular marker assisted selection technology in Momordica charantia disease resistance breeding.

The utility model relates to the technical field of extraction devices, in particular to a momordica grosvenori spice extraction device with a high-efficiency liquid layer separation function, which comprises a bottom plate, a separation barrel fixed with the bottom plate through a plurality of supporting legs is arranged above the bottom plate, and a feeding funnel communicated with an inner cavity of the separation barrel is fixed on the top surface of the separation barrel. And a manual valve is mounted on the outer wall of the feeding hopper pipe body. Through the arrangement of the bottom plate, the separation barrel, the supporting legs, the feeding hopper, the manual valve, the discharging pipe and the electromagnetic valve, liquid layer separation treatment can be conducted on an extracting solution, a collecting pipe of an external collecting device is tightly connected with a liquid outlet pipe in a sleeved mode, and the height of a liquid suction pipe can be adjusted through the design of the separation mechanism; the height of the liquid suction pipe can be adjusted according to the height of a liquid layer interface, liquid on the upper layer can be sucked out conveniently, manual separation in a pouring mode is not needed, extraction liquid and an original solution are prevented from being mixed together again, and the extraction effect of the whole device is better.

1. The name of the design product: packaging bag (momordica fruit and chrysanthemum tea). 2. The use of the design product: for packaging. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best indicates the design points: the unfolded view. 5. The design product is a thin product, and the left view, right view, top view and bottom view are omitted.

The invention discloses a preparation method of fructus momordicae effervescent tablets, and belongs to the technical field of effervescent tablet preparation. The method comprises the following steps: performing ultrasonic-assisted decoction extraction, concentration and spray drying on siraitia grosvenorii to obtain extract dry powder; mixing with alginic acid and malic acid to form a suspension, and drying and crushing to obtain composite powder; then, a hydroxypropyl-beta-cyclodextrin solution is used for carrying out clathration on the composite powder, and clathrated composite powder is obtained after drying; and finally, respectively granulating with auxiliary materials such as an effervescing alkali source, an effervescing acid source, a filling agent and the like through acid and alkali, drying, totally mixing and tabletting to prepare the effervescent tablets. Alginic acid and malic acid are compounded to improve the hydrophilicity and dispersity of the fructus momordicae extract, hydroxypropyl-beta-cyclodextrin is used for inclusion to improve the stability and moisture resistance of effective components, the problems that in a traditional technology, the extract is not uniform in dissolution and prone to moisture absorption, and active components are prone to degradation are solved, and the product is fast in disintegration, good in taste and long in storage life.

The invention discloses Candida albicans long-chain non-coding RNA (Ribonucleic Acid) for apparent regulation of fluconazole drug resistance and application thereof, belongs to the technical field of biological medicines, and relates to antifungal medicines. The number of the long-chain non-coding RNA for epigenetic regulation and control of fluconazole drug resistance is three, and the nucleotide sequences of the long-chain non-coding RNA are shown as SEQ ID NO.1-3. The invention also provides an application of the balsam pear protein MAP30 in inhibiting the expression of long-chain non-coding RNA (Ribonucleic Acid) of a candida albicans genome. The invention provides nucleotide sequencing of Candida albicans genome long-chain non-coding RNA for epigenetic regulation of fluconazole resistance, ORF (open reading frame) comparison, positioning of lncRNA on chromosomes, inhibition of lncRNA expression by using balsam pear protein MAP30, realization of reversion of fluconazole resistance, and theoretical basis for revealing of a Candida albicans resistance mechanism and development of new antifungal drugs and treatment strategies.

The invention relates to the technical field of functional food, and particularly discloses a synergistic fat-reducing composition based on a supramolecular inclusion technology and application thereof.The composition comprises four active extracts including rhizoma polygonati polysaccharide (larger than or equal to 50%), momordica saponin (larger than or equal to 30%), chlorogenic acid (larger than or equal to 40%) and nuciferine (larger than or equal to 20%). The composition is prepared from the following active ingredients in parts by mass: 1-10 parts of rhizoma polygonati, 1-8 parts of bitter gourd, 0.5-5 parts of coffee and 0.5-5 parts of lotus leaves (optimally 5: 4: 2: 2) through molecular inclusion with hydroxypropyl-beta-cyclodextrin or sulfobutyl ether-beta-cyclodextrin. The inclusion ratio is (1: 0.5)-(1: 10), and the composition comprises the following active ingredients in parts by mass: 1-10 parts of rhizoma polygonati, 1-8 parts of bitter gourd, 0.5-5 parts of coffee and 0.5-5 parts of lotus leaves. The problem of multi-component phase separation is solved through supramolecular inclusion, the bioavailability is improved, and triple synergistic fat reduction of inhibiting fat synthesis (FAS), activating decomposition (ATGL) and improving adiponectin is realized. The composition can be used for preparing fat-reducing functional food or health-care products, and the effect of the composition is obviously superior to that of single-component or physical mixed products.

The invention discloses targeted prebiotic plant extraction dietary powder for conditioning hyperglycemia and a preparation method of the targeted prebiotic plant extraction dietary powder. According to the invention, a step-by-step precise treatment technology is adopted, so that the stability and functionality of the core active component are ensured. After the plant extract is dehydrated at low temperature, the biological activity of hypoglycemic substances such as mulberry leaf DNJ and balsam pear glycoside is reserved; the probiotics form a gastric acid-resistant barrier through a micro-capsule embedding technology, so that the colonization rate of strains in intestinal tracts is guaranteed; the triple mixing process enables the sugar blocking component and the metabolism activation component to be uniformly distributed, and synergistically exerts the sugar control effect. In the preparation process, the quality guarantee period of the product is effectively prolonged through nitrogen-filled packaging and water activity control, effective components are prevented from being oxidized and inactivated, and a reliable guarantee is provided for long-term conditioning. The compounding process of the prebiotic particles and the microencapsulated strains strengthens the reconstruction capability of intestinal flora and promotes the generation of short-chain fatty acids so as to improve the insulin sensitivity; the final product mixing and homogenizing technology ensures that the dosage of each bag is accurate, and the individual requirements of blood glucose management are met.

A composition containing a Momordica charantia-derived exosome and a Momordica charantia insulin receptor-binding protein for use in lowering blood glucose level in a subject in need thereof. A weight ratio of the Momordica charantia-derived exosome to the Momordica charantia insulin receptor-binding protein ranges from 2:1 to 5:1. The composition is a food product or a pharmaceutical composition.