8888 results about "Saponin" patented technology

Rebaudioside M compositions with improved aqueous solubility and methods for preparing the same are provided herein. The rebaudioside M compositions include (i) disordered crystalline compositions comprising rebaudioside M and rebaudioside D, (ii) spray-dried compositions comprising rebaudioside M, rebaudioside D and steviol glycoside mixtures and/or rebaudioside B and/or NSF-02, (iii) spray-dried compositions comprising rebaudioside M, rebaudioside D and at least one surfactant, polymer, saponin, carbohydrate, polyol, preservative or a combination thereof. Sweetened compositions, such a beverages, containing the rebaudioside M compositions with improved water solubility are also provided herein.

The present invention relates generally to functional sweetener compositions comprising non-caloric or low-caloric natural and/or synthetic high-potency sweeteners and methods for making and using them. In particular, the present invention relates to different functional sweetener compositions comprising at least one non-caloric or low-caloric natural and/or synthetic high potency sweetener, at least one sweet taste improving composition, and at least one functional ingredient, such as saponin. The present invention also relates to functional sweetener compositions and methods that can improve the tastes of non-caloric or low-caloric high-potency sweeteners by imparting a more sugar-like taste or characteristic. In particular, the functional sweetener compositions and methods provide a more sugar-like temporal profile, including sweetness onset and sweetness linger, and/or a more sugar-like flavor profile.

It is intended to easily separate saponins from isoflavones extracted from starting soybeans thereby giving highly pure saponins at a high yield on an industrial scale. Saponins can be highly efficiently separated from isoflavones by performing multistage extraction under mild conditions such that malonyl isoflavone glycoside, from among isoflavones contained in the starting soybeans, is not converted into isoflavone glycoside, acetyl isoflavone glycoside or isoflavone aglycon. Thus, highly pure saponins can be obtained at a high yield on an industrial scale.

This invention provides compositions, methods and process of producing extracts and pure compounds from Xanthoceras sorbifolia. The extract comprises saponins and other constituents including alkaloids, coumarins, saccharides, proteins, polysaccharides, glycosides, tannins, acid, flavonoids and others. The composition can be used for treating cancer and other conditions, such as arthritis, rheumatism, poor circulation, arteriosclerosis, Raynaud's syndrome, angina pectoris, cardiac disorder, coronary heart disease, headache, kidney disorder, and impotence; for improving cerebral functions; or for curing enuresis, frequent micturition, urinary incontinence, dementia, weak intelligence and Alzheimer's disease, autism, brain trauma, Parkinson's, cerebral dysfunctions, and treating arthritis, rheumatism, poor circulation, arteriosclerosis, Raynaud's syndrome, angina pectoris, cardiac disorder, headache, dizziness, kidney disorder. This invention provides compounds of oleanene triterpenoidal saponin in nature with the characteristics that at least one angeloyl group attache to Carbon 21 or/and 22, or/and linked to the sugar. The compounds of the present invention have various pharmaceutical and therapeutic applications.

The invention discloses multi-herb antibacterial liquid, relates to an external medicament for treating skin diseases and a preparation method thereof, and belongs to a medical external medicament. The external liquid medicine for treating various skin diseases comprises the following medicinal components by weight: 10-20 g of folium artemisiae argyi, 10-15 g of white mulberry branch, 10-15 g of angelica root, 10-15 g of galanga, 5-20 g of isatis root, 10-15 g of mint, 10-15 g of schizonepeta, 10-15 g of lithospermum, 5-15 g of fructus forsythiaev, 10-20 g of cortex dictamni, 10-15 g of rhizoma atractylodis, 10-15 g of tuber of stemona, 10-15 g of corktree, 10-20 g of cicada slough, 10-20 g of honeysuckle, 10-15 g of divaricate saposhnikovia root, 10-15 g of scutellaria baicalensis, 10-20 g of sophora flower, 5-15 g of pepper, 10-15 g of root-bark of Chinese wolfberry, 10-15 g of seed of Job's tears, 10-15 g of cinnamon, 10-15 g of coptis, 10-20 g of astragalus root, 10-15 g of golden larch bark, 10-15 g of rhubarb, 10-20 g of safflower, 10-20 g of radix sophorae flavescentis, 10-15 g of ephedra, 5-15 g of black snake, 10-20 g of angelica, 10-15 g of asarum, 10-15 g of vermilion, 5-10 g of borneol, 5-15 g of long-noded pit viper, 10-15 g of saponin, 5-10 g of cantharis, 10-15 g of fructus cnidii and 3,200 ml of 60-degree spirit brewed from store-up grains. A product provided by the invention is dark brown liquid and has the smell of Chinese herbal medicines and mild fragrance of wine. The 39 raw material medicaments included in the product are processed through seven operation processes.

The present invention relates to pharmaceutical compositions and methods for the prevention and treatment of autoimmune diseases, infectious diseases, neurodegenerative diseases, and primary and metastatic neoplastic diseases. In the practice of the invention, the compositions are employed comprising: (a) a heat shock protein (hsp) or an alpha(2)macroglobulin (alpha2M); (b) a saponin; and, optionally, (c) an antigenic molecule. The antigenic molecule displays the antigenicity of an antigen of: (a) a cell that elicits an autoimmune response; (b) an agent of an infectious disease; (c) a cancerous cell; or (d) a cell or structure associated with a neurodegenerative or amyloid disease. The hsps that can be used in the practice of the invention include but are not limited to hsp70, hsp90, gp96, calreticulin, hsp 110, grp 170, and PDI, alone or in combination with each other. The antigenic molecule can be covalently or noncovalently bound to the hsp or alpha2M, free in solution, and/or covalently bound to the saponin. The compositions of the invention can be administered alone or in combination with the administration of antigen presenting cells sensitized with an hsp- or alpha2M-antigenic molecule complex.

The present invention discloses a balanced nutrient tea and beverage. Its raw material composition includes (by weight portion) 0.5-3 portions of American ginseng, 1-3 portions of sterculia, 2-5 portions of dried longan flesh, 2-5 portions of dried jujube, 2-5 portions of dried apricot flesh, 1-3 portions of spiny jujube kernel, 1-4 portions of lyceum berry, 2-5 portions of raisins, 1-3 portions of tea, 0.5-3 portions of lonicera flower, 0.5-2 portions of notoginseng flower and 1-15 portions of honey. Said invention contains several nutrient components of vitamins, amino acids, saponin, mineral and organic acid, etc. and has several health-care functions of raising immunity of human body, etc.

The invention discloses an external skin care product capable of adjusting skin immunity and delaying skin aging. The external skin care product is characterized by comprising powder, an aqueous solution and emulsion, wherein the powder comprises oligopeptide-1 and ginsenoside; the aqueous solution comprises glycyrrhiza glabra root extract, artemisia capillaris flower extract, mulberry root extract, jujube fruit extract, scutellaria root extract, hydrolyzed rice protein and nicotinamide; and the emulsion comprises hgytantriol bifida ferment lysate, creatine, carnosine, alpha glucosyl hesperidin, hexapeptide-3, centella asiatica extract, coenzyme Q10 inclusion complex, opuntia ficus-indica stem extract, rhodiola rosea extract, saussurea involucrate extract, pseudo-ginseng root extract and Chinese angelica extract inclusion complex. According to the external skin care product, the powder, the aqueous solution and the emulsion are jointly used, and the external skin care product can reduce wrinkle and pachulosis, even skin tone and improve skin elasticity and skin firmness, so that the skin is finer and smoother and looks young.

This invention provides virosome preparations from an enveloped virus, in particular from influenza virus, containing from said virus, and a saponin adjuvant. In particular the invention provides a virosome preparation from influenza virus an influenza antigen a QS21, optionally with a sterol. The invention also provides vaccine compositions containing said virosome preparations, methods of preparing said virosome preparations and vaccine containing them.

The present invention provides for a novel oil-in-water (O/W) emulsion, with increased stability in the presence of bacterial or viral suspensions, especially those concentrated and non-purified (crude extracts) or minimally purified. The emulsion of the present invention can act as vehicle for the delivery of a pharmaceutical composition comprising at least one immunogen and, in particular, an immunogen selected from the group consisting of an inactivated pathogen, an attenuated pathogen, a subunit, a recombinant expression vector, and a plasmid or combinations thereof.

This invention relates to a combination therapy that finds utility in the treatment or prophylaxis of infectious diseases, cancers, autoimmune diseases and related conditions. In particular, the combination therapy comprises the administration of a TH-1 cytokine, in particular, IL-18, and an immunogenic composition, in particular, a vaccine, comprising an antigen and a saponin adjuvant. In particular, the invention relates to the use of IL-18 or bioactive fragment or variant thereof and an immunogenic composition comprising a tumour-associated antigen and a saponin adjuvant, for the treatment of preneoplasic lesions or cancer.

The invention relates to a down jacket cleaning agent which comprises the following components in parts by mass: 1-30 parts of anion surface active agent, 1-15 parts of nonionic surface active agent, 1-10 parts of DP-3000, 0.1-10 parts of tea saponin, 0.1-10 parts of soybean ethyl sulfate morpholine, 0.1-10 parts of ColtideHSi, 0.1-1 part of essence, 0.1-1 part of sodium citrate and 13-97.4 parts of deionized water. The cleaning agent provided by the invention can integrate sterilization, flavor removal and conditioning into a whole and has the advantages of high detergency, high stability, adaptability in cold and hot water and neutrality without damaging hands.

The invention discloses a method for preparing total saponins and polysaccharides from Apios americana flowers simultaneously and relates to the technical field of plant extraction. The method comprises the following steps: (1) harvesting raw materials, cleaning and drying; (2) reflux-extracting with ethanol, and filtering to obtain a supernatant and filter residues; (3) defatting the supernatant with petroleum ether, extracting with n-butanol, performing adsorption and elution, concentrating, and drying to obtain powdery Apios americana flower saponins; (4) removing the solvent from the filter residues, reflux-extracting with water, filtering, collecting and mixing the filtrates; and (5) decolorizing the filtrate, performing deproteinization, concentrating, precipitating with alcohols, dialyzing and concentrating, and drying to obtain Apios americana flower polysaccharides. The method has the advantages of simple process, high yield and low cost. Besides, the total saponins and polysaccharides of Apios americana flowers are prepared simultaneously, have high purity and strong activity, and can be widely used in pharmaceuticals or functional foods with antioxidant and blood sugar regulating effects.

The present invention provides a pharmaceutical composition containing steroidal saponins. The pharmaceutical composition comprises 5˜25 parts by weight of furostanal saponins represented by general formula A or general formula B and 1˜10 parts by weight of spirostanol saponin represented by general formula C. The present invention further provides a method for preparing the pharmaceutical composition. After determination of the three steroidal saponin components in the pharmaceutical composition of the present invention, it is proved that it has high stability and liability in its therapeutic effect. Meanwhile, the method to identify the three steroidal saponins is provided with reliable controllability. Besides, with its daily dosage of 300˜600 mg, which is less dosage, the drug of this invention provides a new choice in clinics.

A process for preparing high-purity momordicoside from fructus momordicae includes such steps as pulverizing, reflux extracting in alcohol, filtering to obtain extract A, suspending it in water, extracting in ethyl acetate 1-3 times, recovering ethyl acetate mother liquid, extracting in n-butanol 1-3 times, recovering n-butanol to obtain extract B, passing it through polyamide column, water washing, concentrating to obtain coarse saponin, chromatography by silica gel column, eluting with chloroform-methanol-water, collecting coarse momordicoside V, chromatography, water washing, eluting with alcohol, and collecting product.

A process for preparing the common saponin of Chinese paris rhizome includes such steps as extracting, separating and purifying, and features that the extracting in alcohol, membrane filtering, resin adsorbing, resin decoloring, decoloring with activated carbon and defatting with acetone are combined. Its advantages are high extracting rate and low cost.

The invention relates to a method for extracting tea saponin from oil tea cakes. The method includes the following steps: (1) grinding; (2) dezymotization; (3) adding water with the temperature of 35 DEG C to 45 DEG C to extract the dezymotized oil tea cake for 4 to 6 hours; (4) using a microstainer to finely filter the extract obtained in step 3; (5) using a hyperfiltration membrane made of polyethersulfone resin to purify the filtrate obtained in step 4, and using a nanofiltration membrane made of polyethersulfone resin for dehydration and concentration; and (6) decolorization and spray drying. The method has the advantages of simple and safe operation, less equipment investment, low production cost and little energy consumption, the yield is more than 75 percent, the purity of the obtained tea saponin product is larger than or equal to 90 percent, and the method is suitable for industrialized production.

Saponins from plant materials are alkaline modified and used as molluscicides.