The invention discloses a super-hydrophobic and super-oleophylic oil-water separating mesh membrane and a preparation method thereof. The method comprises the following steps of: (1), cleaning a fabric mesh and drying the cleaned fabric mesh; (2), dissolving dopamine hydrochloride and trihytdroxy methyl-aminomethane to water to acquire a mixed solution, wherein the pH value of the mixed solution is 8.0-12.0; (3), soaking the dried fabric mesh in the mixed solution, and then getting out the soaked fabric mesh for drying; (4), dissolving mercaptan compound and sodium hydroxide in water to acquire mixed turbid liquid; (5), soaking the fabric mesh acquired in the step (3) in the mixed turbid liquid, reacting the mixture to acquire the oil-water separating mesh membrane. The oil-water separating mesh membrane disclosed by the invention has high bearing pressure to water so that oil can quickly pass, a separating effect is good, the speed is high, and the separating effect on normal hexane, petroleum ether, benzene, gasoline, diesel oil, animal and vegetable oil, crude oil and the like is good. The oil-water separating mesh membrane is non-toxic and harmless, environment-friendly, easy to clean and keep, can be reusable, and has good stability.