576 results about "Wound dressing" patented technology

The invention provides a wound dressing for diminishing inflammation, easing pain and promoting wound healing and a preparation method thereof. The wound dressing capable of diminishing inflammation, easing pain and promoting wound healing is prepared from the following components in parts by mass: 6 to 10 parts of oxidized sodium alginate, 7 to 9 parts of hydrazide gelatin, 1 to 1.5 parts of tannic acid, 8 to 12 parts of polyethylene glycol, 0.05 to 0.1 part of cannabidiol, 0.05 to 0.1 part of neomycin sulfate, 0.2 to 0.3 part of 2-roots alcohol, 0.02 to 0.04 part of vitamin C palmitate and 0.03 to 0.1 part of epsilon-polylysine. The dressing can achieve excellent effects of diminishing inflammation, easing pain and promoting wound healing through synergistic cooperation of all the components.

The invention discloses a polylipoic acid-based composite sponge wound dressing and a preparation method and application thereof.The preparation method comprises the following steps that polylipoic acid amide with amino is obtained through disulfide bond ring opening polymerization, and the polylipoic acid amide and an aldehyde cross-linking agent are jointly dissolved in ethyl alcohol to form a solution A; carrying out high-speed shearing, dispersing and foaming on the water-soluble polymer, and freeze-drying to form porous sponge B; the porous sponge B is soaked in the solution A to be subjected to a cross-linking reaction, vacuum drying is conducted, and the polylipoic acid-based composite sponge wound dressing is obtained. The preparation method has the characteristics of simple preparation process, safety and no toxicity, the polylipoic acid with excellent oxidation resistance is introduced into the medical sponge material, the preparation method of the polylipoic acid medical porous structure material is obtained, the oxidation resistance and the wet viscosity of the medical sponge material are improved, and the medical sponge material has good application prospects. The application of the polylipoic acid-based porous material in the fields of hemostatic materials and wound dressings is realized.

A negative pressure wound therapy system includes a wound dressing, at least one pump fluidly coupled to the fluid interface, a pressure sensor fluidly coupled to the wound dressing, a control housing, and an electrical coupler. The wound dressing includes a sealing layer, an absorbent layer adjacent to the sealing layer, and a fluid interface attached to at least one of the sealing layer or the absorbent layer. The at least one pump is configured to apply negative pressure to the fluid interface to draw fluid from the wound dressing via the fluid interface. The pressure sensor is configured to detect a fluid pressure of the wound dressing. The control housing is remote from the wound dressing. The electrical coupler is configured to removably connect the control housing to the at least one pump.

The invention discloses a sugar response hydrogel wound dressing based on Prussian blue nano-enzyme and bacterial cellulose as well as a preparation method and application of the sugar response hydrogel wound dressing, and belongs to the field of medical dressings and biological materials. The sugar-responsive hydrogel wound dressing is good in mechanical property, and can be subjected to cascade reaction to play antibacterial and anti-inflammatory roles. The preparation method comprises the following steps: preparing Prussian blue nano-enzyme (PBNPs) by adopting a one-pot method and utilizing a self-polymerization reaction, and preparing a Prussian blue nano-enzyme bacterial cellulose compound by utilizing an isotonic adsorption method; glucose oxidase (GOx) is loaded on BC coated PBNPs by adopting an in-situ polymerization method, the sugar response hydrogel wound dressing based on PBNPs and BC is obtained, the preparation method is simple in process, and the obtained sugar response hydrogel wound dressing is good in stability, suitable for factory production and hopeful to be applied to diabetes wound treatment. Meanwhile, the PBNPs are applied to the field of diabetic wound dressings, and the application direction of the PBNPs is widened.

The invention relates to an enzyme response antibacterial carbon dot and a preparation method and application thereof.The carbon dot takes a copper-doped carbon dot as a core and is covalently grafted with a hyaluronic acid shell layer through amidation reaction to form a composite nano material Cu-CDs (at) HA, specifically, soluble copper salt and folic acid are subjected to a hydrothermal reaction to obtain the copper-doped carbon dot, carboxyl is activated through EDC / NHS in a buffer system, and the carbon dot is prepared. And performing grafting reaction with hyaluronic acid to obtain a target product. The hyaluronidase-containing antibacterial composition can be specifically degraded and release antibacterial components under the action of hyaluronidase, shows good bacterial responsive bactericidal performance, has the minimum inhibitory concentrations of 8 g / mL and 16 g / mL for staphylococcus aureus and escherichia coli respectively, and has peroxidase-like activity and free radical scavenging capacity. The antibacterial carbon dots can be used for preparing intelligent wound dressings, antibacterial coatings and other biomedical materials, and have the advantages of responsive drug release, efficient antibacterial property and promotion of wound repair.

Embodiments of negative pressure wound therapy systems and methods are disclosed. In one embodiment, an apparatus includes a housing, a negative pressure source, a canister, an antenna, and one or more controllers. The negative pressure source can provide negative pressure via a fluid flow path to a wound dressing. The canister can be positioned in the fluid flow path and collect fluid removed from the wound dressing. The antenna can be supported by the housing and wirelessly communicate with an electronic device. The antenna can be oriented in the housing to face downward toward the ground when the negative pressure source is providing negative pressure. The one or more controllers can activate and deactivate the negative pressure source and transmit first data to the electronic device using the antenna or receive second data from the electronic device using the antenna.

The invention provides a programmable hydrogel wound dressing with rotation contraction force and application thereof, and belongs to the technical field of biomedical materials, the programmable hydrogel wound dressing comprises a dual-network hydrogel main body, a first hydrogel layer, a second hydrogel layer, a first hydrogel layer and a second hydrogel layer, and the dual-network hydrogel main body is composed of a first network and a second network; the first network is a chemically cross-linked methacrylated hyaluronic acid network and forms a cross-linked network structure through photopolymerization; the second network is a physical cross-linked polyvinyl alcohol network, and forms an instantaneous cross-linking point with a crystal region through a hydrogen bond, so that the hydrogel is endowed with shape memory performance; the surface is modified with an N-hydroxysuccinimide ester functional group, and the N-hydroxysuccinimide ester functional group and amino of wound tissue protein can form a covalent bond; the dual-network hydrogel main body is subjected to pre-stretching or pre-twisting treatment and then is dried and shaped into a preset shape, the initial shape is recovered after moisture is absorbed, and rotary contraction mechanical force is output. Rapid wound healing and scar-free regeneration are achieved by dynamically regulating and controlling wound edge mechanical force and enhancing tissue adhesion, and then application to regulation and control of wound microenvironment to promote scar-free healing is achieved.

The application discloses a kind of super tough polyvinyl alcohol composite hydrogel with biological activity and preparation method thereof.The polyvinyl alcohol composite hydrogel refers to that polyvinyl alcohol (PVA) is added into NaOH solution, heated to 90 DEG C, and stirred vigorously for 2 hours, after PVA is completely dissolved, a certain proportion of sodium lignosulfonate (LS) and rutin (RT) powder is added, after sodium lignosulfonate and rutin are completely dissolved, it is air-dried into 0.3~0.5 mm thick film at room temperature, then it is immersed in 20~30 mL 10 wt% NaCl solution and swells for 3~5 hours, to obtain PVA-LS-RT composite hydrogel.The polyvinyl alcohol composite hydrogel prepared by the application has super strong mechanical property, and has higher antibacterial, antioxidant and wound healing capacity, and has good application prospect in wound dressing, artificial cartilage and flexible electronics and other cutting-edge fields.

The present invention relates to a wound dressing comprising an absorbent core, the absorbent core comprising a first group of superabsorbent particles characterized in that the superabsorbent particles of the first group are encapsulated in a first water-soluble material. The invention further relates to an absorbent core for such a wound dressing.

The invention belongs to the technical field of medical sensing, and relates to a wound monitoring bandage and method based on flexible passive inductance-capacitance resonance sensing. Comprising a contact wound dressing; the sensor assembly comprises a first transparent dressing packaging layer, a second transparent dressing packaging layer and an LC resonance sensor, the first transparent dressing packaging layer and the second transparent dressing packaging layer are arranged in a stacked mode, the LC resonance sensor is packaged between the first transparent dressing packaging layer and the second transparent dressing packaging layer, and the LC resonance sensor is of a planar spiral structure; the second transparent dressing packaging layer is arranged at the top of the contact wound dressing; and the transparent dressing fixing layer covers and fixes the sensor assembly and the contact wound dressing. The problems that in the prior art, wound healing state evaluation depends on subjective experience, continuous real-time monitoring cannot be achieved, the healing environment is prone to being damaged and infection is caused by frequent dressing replacement are solved, and the dual functions of objective, continuous and non-invasive monitoring on the wound healing process and active healing promotion are achieved.

The invention relates to the technical field of biomedical engineering and pharmacology and relates to, but is not limited to, a method for the composition and production of a wound dressing for the healing of complete and chronic skin wounds.

The utility model discloses an ear postoperative wound dressing fixer, which belongs to the technical field of ear postoperative nursing and comprises a first mounting lantern ring, a dressing mechanism is arranged on the outer side of the first mounting lantern ring, a wearing mechanism is arranged above the first mounting lantern ring, and a mounting ring is fixedly mounted at the left end of the first mounting lantern ring. The fixing device comprises a mounting ring, a supporting rod is fixedly mounted on the inner wall of the mounting ring, a threaded seat is fixedly mounted on the supporting rod, a fixing screw is in threaded connection with the inner side of the threaded seat, and the fixing device for the wound dressing after the ear surgery is composed of a first mounting lantern ring, a dressing mechanism and a wearing mechanism. According to the fixator, a double-installation-sleeve-ring linkage structure is combined with a multi-point adjustable pressure system of the dressing mechanism, the gauze body is flexibly fixed, the problem that adhesive tape is prone to falling off is solved, the wearing mechanism is double fixed through insertion plate type telescopic adjustment and elastic hook-and-loop fasteners, under the assistance of a ventilation groove and a soft cotton cushion, the displacement amount is reduced, and the skin pressure is reduced; stability and comfort are achieved, and the postoperative nursing quality is effectively improved.

The invention discloses a thoracic surgery wound dressing change whole-course sterile protection intelligent operation mechanism which comprises an operation mechanism, a limiting mechanism and a fixing buckle, and the operation mechanism, the limiting mechanism and the fixing buckle are arranged in an upper-middle-lower structure; the operating mechanism comprises a middle pad, a first fixing block, a first breaking ball, a positive pole magnetic plate, a first placement groove, a limiting column, a rotating hole, a rotating shaft, a rotating roller, a fixing rubber column, a first visual film, a top pad, a second fixing block, a second breaking ball, a negative pole magnetic plate, a second placement groove, a first fixing hole, a second fixing hole, a breathable film, a third fixing block, a flexible film sensor, a fixing ring, a second visual film and a soft sealing buffer ring. The first through groove is arranged in the first through groove. According to the scheme, by means of the integrated design of intelligent monitoring, dynamic sealing, convenient operation and close fitting, the problem of pain points in the prior art is solved, upgrading from passive protection to active monitoring is achieved, and the whole-process sterility, operation efficiency and wearing experience are all considered.

A wound dressing having backing layer and a plurality of absorbent layers, wherein a first absorbent layer comprises a non-woven fabric having 60 to about 95 wt% gelling fibres and 5 to about 40 wt% non-gelling fibres, of the absorbent layer and wherein a second absorbent layer is located between the backing layer and the first absorbent layer, and the second absorbent layer having a higher fluid absorbency and / or a higher hydrophilicity than the first absorbent layer. Manufacturing processes and applications of said dressing are also described.

1. The name of the design product: wound anastomat. 2. The use of the design product: for wound dressing and suture. 3. The design points of the design product: in the combination of shape and pattern. 4. The picture or photo that best shows the design points: design 1 perspective view. 5. Other circumstances that need to be explained: design 1 is the basic design.

The invention belongs to the technical field of biomedical materials, and discloses a viola philippica exosome-loaded composite hydrogel as well as a preparation method and application thereof, the composite hydrogel is prepared by mixing methacrylated polylysine (PLMA), oxidized dextran (ODex), viola philippica exosome (V-E), a photoinitiator and a physiologically compatible solvent and performing illumination crosslinking; the preparation method comprises the following steps: respectively preparing PLMA and ODex solutions, extracting and purifying V-E, adding a photo-crosslinking agent (LAP), mixing the components to obtain a precursor liquid, and carrying out in-situ curing molding through ultraviolet-visible light irradiation. The composite hydrogel provided by the invention solves the problems that the existing wound dressing is difficult to fit with irregular wounds, is antibacterial and easy to resist drugs, and lacks active anti-inflammatory and efficient healing promotion capabilities, and is suitable for repair treatment of infectious open wounds such as burns, trauma, diabetic foot ulcer and postoperative infected incisions.

The present application relates to the technical fields of corn disease resistance research, a kind of corn stem stem after drilling wound smearing tool, including shell, the shell inside is provided with connecting shaft, one end of the connecting shaft is fixedly connected with smearing part, another shell is also provided with the drive mechanism of moving back and forth with the connecting shaft and smearing part, another in the shell is provided with medicine box, the medicine box outside is connected with lifting connecting mechanism, the lifting connecting mechanism is connected with drive mechanism, for driving the medicine box moves up and down.The present application is moved by the cooperation of drive mechanism and connecting shaft, drives smearing part to rotate while moving, the ointment on smearing part is applied to the inner wall of small hole, and the small hole on the corn stem is protected, which provides guarantee for subsequent smooth observation of corn inoculation colony manifestation, in addition, the present application is moved up and down by controlling medicine box, so that smearing part will automatically dip the ointment in medicine box during movement, facilitate continuous work of smearing part, improve efficiency.

The invention relates to a preparation method of bio-based dual-network intelligent medical hydrogel, and relates to a preparation method of high polymer material medical hydrogel, the hydrogel takes bio-based material microcrystalline cellulose as a raw material, the bio-based material microcrystalline cellulose and a green cross-linking agent citric acid are esterified and cross-linked to form single-network (SN) hydrogel, and the single-network hydrogel and the green cross-linking agent citric acid are further subjected to solution treatment to form dual-network (DN) hydrogel. Anthocyanin is introduced in the process of forming the double-network hydrogel. In the SN forming process, risks possibly caused by toxic residues of a chemical cross-linking agent are effectively avoided; the anthocyanin is used as a natural antioxidant, so that the hydrogel has the functions of eliminating free radicals, resisting cancer, resisting inflammation, inhibiting bacteria and the like; meanwhile, due to the introduction of anthocyanin, the prepared DN hydrogel has excellent mechanical properties and obvious pH response, and can be applied to the field of wound dressings. The wound healing condition can be judged according to the color change caused by pH fluctuation, the unnecessary dressing replacement frequency is reduced, and the treatment efficiency is improved.

Hydrocolloid-based wound dressings and backing layers thereof are described. The backing layer may include a carrier film prepared from a carrier film composition. The carrier film composition may include a surface active agent and a combination of first and second aromatic polyester-based thermoplastic polyurethanes. The combination of the first and second aromatic polyester-based thermoplastic polyurethanes may provide a wrinkle-free carrier film under accelerated aging conditions. The hydrocolloid-based wound dressing may include an adhesive layer and the backing layer disposed on the adhesive layer. Methods for preparing the backing layer may include contacting the first aromatic polyester-based thermoplastic polyurethane, the second aromatic polyester-based thermoplastic polyurethane, and the surface active agent with one another to prepare a mixture. The method may also include melting and homogenizing the mixture in an extruder, and extrusion casting the melted mixture on the carrier substrate to prepare the backing layer.

The present disclosure generally relates to an electronic circuit patch (1) for use in conjunction with a wound dressing (2) and having a lateral (x) and a longitudinal (y) extension, wherein the patch (1) comprises: - a transfer layer (3) having a top side (3a) and a bottom side (3b), wherein at least the bottom side (3b) is adhesive; - a support layer (4) arranged on top side (3a) of the transfer layer (3); and - a release liner (5) releasably attached to the bottom side (3b) of the transfer layer (3), wherein the patch (1) comprises an aperture (6) extending through at least the transfer layer (3), and wherein the patch (1) comprises a first electronic circuit (7) arranged along at least a portion of the aperture (6). The present disclosure also relates to a wound dressing assembly (9) comprising the electronic circuit patch (1) and a wound dressing (2).

The utility model relates to nursing instrument technical field, and disclose a kind of diabetic foot protection device, including protection device bottom pad, the top of protection device bottom pad is equipped with flexible protection body, the side of protection device bottom pad is equipped with rotating shaft, the side of rotating shaft is rotatably connected with hard protection body, the side of protection device bottom pad is fixedly connected with first connecting block, the side of hard protection body is fixedly connected with connecting plate, the top of first connecting block is equipped with the insertion slot, the top of connecting plate is fixedly connected with second connecting block, the one end of second connecting block is equipped with structure slot.The foot protection device for lower limb nursing of diabetic patient can make medical staff more conveniently observe and replace the wound dressing of affected side toe, help to prevent disease from getting worse, and improve the efficiency of nursing work, at the same time, it reduces the discomfort of patient suffered from repeatedly wearing protection device.

The present invention concerns extensible absorbent wound dressings. The wound dressing has a wound contact layer having a proximal surface facing toward the wound and a distal surface facing away from the wound, and a backing layer having a proximal surface facing toward the wound and a distal surface facing away from the wound, the backing layer having an absorbent region located on a proximal surface thereof, the absorbent region comprising a plurality of discrete absorbent members, wherein the backing layer is configured to be positioned over the wound contact layer, such that the absorbent region is located adjacent to the distal surface of the wound contact layer, and wherein the absorbent region and the wound contact layer are configured to be detached at least in an area inside a perimeter of the absorbent region. The absorbent wound dressings of the present invention can be used to dress so-called truly three-dimensional anatomical areas, such as for example a knee or an elbow.

The invention discloses recombinant collagen III + X as well as a preparation method and application thereof, and belongs to the technical field of biochemical engineering. The amino acid sequence of the recombinant collagen III + X provided by the invention is shown as SEQ ID NO: 1, and the recombinant collagen III + X is formed by repeating human III type collagen 387-467 amino acid fragments twice and connecting human X type collagen 521-680 amino acid fragments to the C end. Experiments prove that the recombinant III + X collagen and proline hydroxylase are co-expressed to form a stable triple helix structure, and the recombinant III + X collagen has great advantages in the aspects of cell migration, safety and the like, and can be used as a raw material for preparing wound dressings and skin care products.

The invention provides a wound dressing for wound hemorrhage. The wound dressing is prepared from the following components in parts by mass: 20 to 25 parts of cationic cassava starch, 10 to 13 parts of polyethylene glycol, 1.2 to 1.8 parts of xanthan gum, 0.1 to 0.2 part of cannabidiol, 6 to 8 parts of tannic acid modified chitosan, 1.8 to 2.5 parts of a polydopamine solution with the concentration of 5mg / mL and 1 to 1.5 parts of nano-hydroxyapatite. The wound dressing has an instant hemostatic effect and a long-acting tissue regeneration induction capability.

The application relates to a machine learning assisted optimization multifunctional composite hydrogel wound dressing and a preparation and optimization method thereof, and belongs to the hydrogel field. The hydrogel is constructed by ion crosslinking of sodium alginate and calcium ions and chitosan quaternary ammonium salt, and a chemical crosslinking network formed by polyacrylamide is interpenetrated with the network. The hydrogel has high water absorption, strong antibacterial property, reliable adhesion, sensitive strain sensing property and excellent mechanical property, and provides ideal healing for wounds. The method innovatively integrates machine learning intelligent optimization: by establishing a formula-process-performance database, training a Gaussian process regression prediction model, and adopting a Bayesian optimization algorithm for global optimization, optimal preparation parameters for specific performance requirements are efficiently and accurately determined. The method breaks through the traditional trial-and-error development mode depending on experience, realizes high performance, customization and rapid development of the hydrogel dressing, and provides a new paradigm for design and preparation of a new generation of wound care products.

The present application relates to the technical field of wound protection, in particular to a wound protection fixing plate and a using method thereof. The wound protection fixing plate comprises a hard plate body; the hard plate body has a curved surface shape which is upwardly convex as a whole, so as to form a protection space below the hard plate body for accommodating a wound dressing and avoiding contact with the wound; a breathable hollow structure is formed on the hard plate body, and a fixing structure for cooperating and fixing a bandage is further arranged. The wound protection fixing plate can provide hard protection for the wound position, has strong breathability, is convenient to wear, and has high wearing comfort.

This invention belongs to the interdisciplinary field of biomedical engineering, materials science, and tissue engineering, and discloses a multifunctional hydrogel with switchable mechanical and adhesive properties based on temperature triggering, its preparation method, and applications. The invention consists of acrylic acid, gelatin, hexadecyltrimethylammonium bromide, polydopamine nanoparticles loaded with silver nanoparticles, and water. This invention not only exhibits excellent adhesion and mechanical properties to skin tissue but also possesses switchable mechanical and adhesive properties, achieving durable and repeatable adhesion. The temperature-triggered hydrogel prepared by this invention is simple to process, low in cost, and introduces no toxic chemicals. It can achieve a close fit at body temperature and natural detachment at low temperatures, driven by temperature, and maintains excellent adhesion properties even in complex environments, thus promoting the development of intelligent medical multifunctional wound dressings.

The application belongs to the technical field of biomedical engineering, and particularly relates to a visual hydrogel wound dressing, a preparation method and application thereof. The visual hydrogel wound dressing provided by the application is a hydrogel fiber membrane; the hydrogel fiber membrane comprises PUA fibers and antibacterial agent-containing nanovesicles dispersed in the PUA fibers; the component of the PUA fibers is a PUA polymer; the preparation raw material of the PUA polymer comprises aqueous polyurethane acrylate and alginate; the antibacterial agent-containing nanovesicles comprise nanovesicles and antibacterial agents loaded in the nanovesicles; and the nanovesicles are formed by PVP-PLA-PVP amphiphilic block copolymer. The wound dressing provided by the application can effectively promote wound healing through the synergistic effect of efficient antibiosis, drug sustained release and visual diagnosis.

The invention discloses an HIPE emulsion for a wound dressing and a preparation method thereof, and the wound dressing, the HIPE emulsion comprises an oil phase, a water phase and an emulsifier, the oil phase comprises a polymer matrix material and a functional additive, and the polymer matrix material comprises a biodegradable synthetic polymer material and a natural polymer material; the wound dressing provided by the invention has the advantages of biocompatibility, excellent mechanical property, multifunctional responsiveness and multi-component healing promotion.

The invention relates to a preparation method of a stable carboxymethyl chitosan wound dressing, and belongs to the technical field of medical dressings. The dressing comprises the following components: 3.2 to 4.5 wt% of carboxymethyl chitosan, 1.1 to 1.6 wt% of a passivation stabilizer, 0.15 to 0.2 wt% of a cross-linking agent, 1.6 to 2.0 wt% of a wetting agent, 0.7 to 0.9 wt% of a humectant and the balance of a PBS (Phosphate Buffer Solution), a polysaccharide chain segment in a molecular chain of the passivation stabilizer is entangled with carboxymethyl chitosan molecules, an ether segment and organic silicon segment alternating structure is introduced to the carboxymethyl chitosan molecular chain, synergistic protection is formed on the carboxymethyl chitosan chain, shrinkage of initial gel under the acid condition and swelling of initial gel under the alkaline condition are inhibited, the pH resistance of the dressing is remarkably improved, and the application prospect is broad. The important application value is realized in the aspects of drug loading and long-acting storage.