1085 results about "High loading" patented technology

The present invention relates to a molecular sustained controlled release system constructed by the conjugation of molecules to be released with biodegradable polyester polymer via covalent bond and method for preparation thereof. In accordance with the present invention, the system may be formulated into microspheres, nanoparticles, or films. The molecular release rate from the above system can be regulated to be proportional to the chemical degradation rate of the biodegradable polyester polymers, resulting in near zero order kinetics profile of release without showing a burst effect, Moreover, a high loading efficiency of hydrophilic drugs can be achieved.

Polymeric delivery devices have been developed which combine high loading/high density of molecules to be delivered with the option of targeting. As used herein, “high density” refers to microparticles having a high density of ligands or coupling agents, which is in the range of 1000-10,000,000, more preferably between 10,000 and 1,000,000 ligands per square micron of microparticle surface area. A general method for incorporating molecules into the surface of biocompatible polymers using materials with an HLB of less than 10, more preferably less than 5, such as fatty acids, has been developed. Because of its ease, generality and flexibility, this method has widespread utility in modifying the surface of polymeric materials for applications in drug delivery and tissue engineering, as well other other fields. Targeted polymeric microparticles have also been developed which encapsulate therapeutic compounds such as drugs, cellular materials or components, and antigens, and have targeting ligands directly bound to the microparticle surface. Preferred applications include use in tissue engineering matrices, wound dressings, bone repair or regeneration materials, and other applications where the microparticles are retained at the site of application or implantation. Another preferred application is in the use of microparticles to deliver anti-proliferative agents to the lining of blood vessels following angioplasty, transplantation or bypass surgery to prevent or decrease restenosis, and in cancer therapy. In still another application, the microparticles are used to treat or prevent macular degeneration when administered to the eye, where agents such as complement inhibitors are administered.

Lithium ion secondary batteries are described that have high total energy, energy density and specific discharge capacity upon cycling at room temperature and at a moderate discharge rate. The improved batteries are based on high loading of positive electrode materials with high energy capacity. This capability is accomplished through the development of positive electrode active materials with very high specific energy capacity that can be loaded at high density into electrodes without sacrificing performance. The high loading of the positive electrode materials in the batteries are facilitated through using a polymer binder that has an average molecular weight higher than 800,000 atomic mass unit.

The present invention is non-contact magnetically adsorbed wall climbing robot, belongs to the field of robot design technology, and aims at providing robot with both high moving flexibility and great loading capacity. The non-contact magnetically adsorbed wall climbing robot includes wheeled moving mechanism and permanent adsorption mechanism. The wheeled moving mechanism includes chassis, driving mechanism and wheels, which are laid symmetrically, driven in differential mode, and turns on wall by means of the speed difference of the wheels. The permanent adsorption mechanism has no contact with the magnetically conducting wall surface, high magnetic energy utilization, and high adsorption capacity. The wall climbing robot has high loading capacity, high motion flexibility, especially high turning flexibility, and excellent application foreground.

A method for treating pulmonary hypertension and other diseases involving a defect in collagen metabolism, by administration of an effective amount of a liposome encapsulated copolymer conjugate antifibrotic composition, is disclosed. The antifibrotic agent is preferably a proline analog, such as cis-4-hydroxy-L-proline (cHyp). Consistent, high loadings (>98%) of the antifibrotic agent are achieved by first forming a dipeptide with L-lysine, after which the dipeptide is copolymerized with the polymer component to form the copolymer conjugate. The polymer is preferably poly(ethylene glycol) having a weight average molecular weight of from about 500 to about 15,000. There is thus provided the efficient delivery and rateable release of the antifibrotic agent to inhibit collagen accumulation and thereby treat the diseases involved. Accordingly, there is a substantial reduction in the quantity of antifibrotic agent necessary, and thus a corresponding reduction in the potential for toxicity that would otherwise result from its prolonged administration.

The invention relates to a construction method for bidirectional spiral expand pile and the bidirectional spiral closed expand bit. The construction method comprises drilling and expanding bore by the bidirectional spiral closed expand bit; pushing soil, which is obtained in drilling and expanding bore downwards, into the side wall of pile bore; the bidirectional spiral closed expand bit rotating upwards to drill and expand the bore again; pushing soil, which is obtained in drilling, expanding and lifting upwards, into the side wall of pile bore; starting the concrete pump to press the pile material into the pile bore while the bit is lifted. The bidirectional spiral closed expand bit comprises a connecting bar. At the lower of the connecting bar spiral expand body, closed expand body and dynamic sealing expand body are assembled on the connecting bar in the same axial line in turn from the bottom to the top or they are machined on the connecting bar together. The invention is provided with high loading capacity, small sedimentation quantity, better quality, low cost and smaller energy consumption so on.

This invention relates to a storage stable, aqueous, herbicidal formulation containing an ultra-high concentration of glyphosate in the isopropylamine, potassium or mixed salt form in combination with a surfactant system, to a method of making the formulation, and to a method of treating unwanted vegetation employing the formulation. The surfactant system employed in the concentrate comprises dialkoxylated alkylamine, water miscible solubilizer and amine oxide. The surfactant system unexpectedly permits the formulation of storage stable, ultra-high loaded aqueous glyphosate salt concentrates possessing high or no cloud points.

The invention discloses a calibrating and loading bench of a large multi-dimensional force transducer. The loading bench comprises an upper cross frame (6), a loading bench column (7), a lower cross frame (8), a multi-dimensional force transducer fixed support (9), loading units and loading blocks (5), wherein each loading unit comprises a loading frame (1), a loading hydraulic cylinder (2), a one-dimensional tension-pressure transducer (3) and a tension bar (4). By combining the different installation positions of the two loading units and the connection position of the tension bars (4) and the loading blocks (5), the calibration and the loading of the multi-dimensional force transducer can be realized. Compared with the prior art, the invention has the advantages of simple and compact structure, large range for calibrating and loading the force and high loading accuracy. Besides, by regulating the pressure of a hydraulic system, the invention can easily realize the continuous adjustment of the loaded force and the automatic and dynamic loading of the calibrated force, thereby being especially applicable to the static and dynamic calibration and loading of the large multi-dimensional force transducer.

Biological nutrient removal (BNR) in municipal wastewater treatment to remove carbonaceous substrates, nutrients and phosphorus, has recently become increasingly popular worldwide due to increasingly stringent regulations. Biological fluidized bed (BFB) technology, which could be potentially used for BNR processes, can provide some advantages such as high efficiency and compact structure. This present invention incorporates the fixed-film biological fluidized bed technology with the biological nutrient removal in a liquid-solid circulating fluidized bed, which has achieved the simultaneous elimination of organic carbon, nitrogen and phosphorus, in a very efficient manner and with very compact space requirements. The BNR-LSCFB has two fluidized beds, running as anoxic/anaerobic and aerobic processes to accomplish simultaneous nitrification and denitrification and to remove carbonaceous substrates, nutrients and phosphorus, with continuous liquid and solids recirculation through the anoxic/anaerobic bed and the aerobic bed. The new BNR-LSCFB system is not only an excellent alternative for conventional activated sludge type BNR technologies but is also capable of processing much higher loadings and suitable for industrial applications.

A compound battery device having a lithium battery and a lead-acid battery includes at least one lithium battery unit, at least one lead-acid battery unit and a control circuit. The lithium and lead-acid battery units are electrically connected in parallel and can have various combinations to meet actual demands of an output voltage. The control circuit is electrically connected to the lithium and lead-acid battery units separately and further comprises a voltage-boosting unit, a voltage-detecting unit, a lithium battery unit management unit and a logic control unit. Thereby, two complementary battery units are connected in parallel, with a control circuit to adjust a voltage thereof, allowing the two battery units to work together to make use of their respective advantages while providing mutual power support. Thus, the compound battery device is capable of more efficient power supply and higher loading, and effectively prevents over-discharge that shortens the battery service life.

Provided herein are nanofibers and processes of preparing nanofibers. In some instances, the nanofibers are metal and/or ceramic nanofibers. In some embodiments, the nanofibers are high quality, high performance nanofibers, highly coherent nanofibers, highly continuous nanofibers, or the like. In some embodiments, the nanofibers have increased coherence, increased length, few voids and/or defects, and/or other advantageous characteristics. In some instances, the nanofibers are produced by electrospinning a fluid stock having a high loading of nanofiber precursor in the fluid stock. In some instances, the fluid stock comprises well mixed and/or uniformly distributed precursor in the fluid stock. In some instances, the fluid stock is converted into a nanofiber comprising few voids, few defects, long or tunable length, and the like.

The invention discloses a comprehensive performance test bench for a planetary roller screw. A driving assembly provides power for the planetary roller screw; a test assembly is used for mounting a planetary roller screw of a different model; a hydraulic loading assembly is adopted to carry out dynamic and static loading on a planetary roller screw nut, load borne by the planetary roller screw during actual work is simulated, and a force closed loop is adopted to ensure accuracy of the loading force. The test bench is provided with a torque sensor, an angle encoder, a circular magnetic grating, a grating ruler, a LVDT, and a force sensor. Measurement on torque, an angle, displacement and force is realized through the sensor. Through analyzing the test data, test on performance of the position precision, the speed, the acceleration, the transmission efficiency, the transmission clearance and the axial stiffness of the planetary roller screw of the different model in the load state can be completed. The test bench has the advantages of simple and flexible structure, thorough and accurate test performance parameters, high loading precision and strong test scalability.

Disclosed is a data-driving automatic testing system which comprises testing tools and testing instruments, devices to be tested, testing platform and function library connected with the testing platform. The function library includes a product function library, a testing tool function library and a testing instrument library; the testing platform includes a testing environment generating module, a test cases generating module, an operation engine, a testing logic generation module and a testing suite generating module. The invention also provides a data-driving automatic testing method. The invention is characterized in that the inventive system and method can be transmitted among platforms and tool platforms; testing environment and testing logic can be shared and overloaded. The invention has the advantages that the function library has high loading efficiency; has low maintain cost; employing testing suite to improve testing efficiency.

The invention discloses a method for controlling channel access of a wireless sensor network. A base station node and each sensor node adopt a time frame structure with different lengths of time frame, so that the sensor nodes can reserve different time slots by dispatching to carry out data packet transmission, thereby not only reducing collision probability of forwarding data packets among sensor nodes in a high-density monitoring area and improving the utilization rate of wireless channel, but also effectively avoiding overhearing in the wireless sensor network and frequent status switching of a transceiver; therefore, the sensor nodes can be in dormancy status as fully as possible during idle transmission so as to greatly reduce energy consumption under the high-loading network condition and have good energy efficiency. A path reserve mechanism can reserve a multi-hop time slot in advance along data packet forwarding direction in time slot reservation phase, according to the time frame synchronizing characteristics of the sensor nodes on a forwarding path, thereby effectively avoiding end-to-end transmission delay of single data packet caused by intermittent transmission of data packets on the forwarding path.

The invention relates to a vehicle mechanical energy-saving hydraulic system adopting a fixed displacement pump. The system comprises a working pump, an auxiliary pump and a steering pump; when an engine is at the lower speed, the auxiliary pump and the steering pump are converged, and the requirement of a steering system on an oil liquid is ensured; when the engine is at the high speed, the auxiliary pump and the working pump are converged, oil is provided to a working system, and the operation efficiency is improved; when the engine has high rotation speed and the working system has higher loading, and the working system requires a high-pressure small-flow-rate oil liquid, the auxiliary pump is subjected to low-pressure unloading through an equivalent unloading valve; an electromagneticvalve is introduced to the outlet of the reducing valve of the steering system, the on-off state of the electromagnetic valve is controlled by control signals which are the signals directly relevant to the engine or the engine rotation speed, and further the working position of a flow changeover valve is controlled, thus the flow direction of the oil liquid output by the auxiliary pump is controlled; and through the hydraulic system, the hydraulic system efficiency is improved, the working is reliable, the structure is simple, and the hydraulic system is easy to implement.

The invention discloses a preparation method of a spinel-type magnetic MFe2O4/graphene composite material. The preparation method utilizes a water-soluble metal M<2+> salt and a Fe<3+> salt as precursors and graphite oxide as a matrix and comprises the following steps of carrying out ultrasonic dispersion of graphite oxide in ethanol or water as a solvent to obtain a graphene oxide dispersion, adding a M<2+> salt and Fe<3+> salt-containing aqueous solution having a M<2+>/Fe<3+> mole ratio of 1: 2 into the graphene oxide dispersion, fully stirring to obtain a mixed solution, adjusting a pH value of the mixed solution to a value more than 10 by an alkali liquor, adding a reducing agent into the mixed solution, stirring at a temperature of 80 to 150 DEG C for a reaction lasting for 4 to 10 hours, after the reaction is finished, carrying out separation, washing, drying and grinding, and carrying out calcination of the grinded powder at a temperature of 300 DEG C in a nitrogen or argon atmosphere for 2 to 10 hours. Magnetic MFe2O4 nano particles of the spinel-type magnetic MFe2O4/graphene composite material have high loading capacity, stable structures, good uniformity, good dispersibility and strong adhesion with graphene. The spinel-type magnetic MFe2O4/graphene composite material can be widely used in the fields of magnetic targeting materials and other related function materials.

The invention relates to a method for preprocessing map display data. The method is characterized by comprising the following steps of: 1) establishing a multi-resolution secondary grid index storage structure, and realizing an estimate read policy on the basis of the index storage structure; 2) controlling the density of a display object of each grid individually to select the reasonable displayobject; and 3) simplifying the display object in each grid by combining the resolution of human eyes. In the method, the high loading efficiency can be obtained in the directional movement display ofa map, the density of display contents in each measuring scale and each area is reasonable, the display objects are simplified on the premise of ensuring the visual effect of the human eyes, and the display data volume is reduced. The method can be widely applied to various vehicle-mounted navigation systems to realize the efficient loading of the map display data.

The invention belongs to the field of a polyolefin catalyst. The method comprises the steps: dissolving or suspending a carrier in an organic solvent; adding compounds of organic lithium, organic sodium or organic potassium or a format reagent to the obtained carrier liquor or suspending liquor at the temperature of -40 DEG C to 30 DEG C; reacting for 0.5 to 3 hours at the temperature of -20 DEG C to 10 DEG C after the adding step; raising the temperature to 30 DEG C to 80 DEG C; reacting for 0.5 to 3 hours; obtaining a mixture; filtering the mixture for washing and removing residual organic lithium, organic sodium, organic potassium or the format reagent; reacting with titanium, metallocene, non-metallocene, vanadium, rare earth metal or chromic halide in the organic solvent at the temperature of -40 DEG C to 30 DEG C; reacting for 0.5 to 3 hours at the temperature of -30 DEG C to 0 DEG C after the adding step; raising the temperature to 20 DEG C to 100 DEG C; reacting for 1 to 5 hours; removing the residual halide by filtering and washing; drying; and obtaining a solid catalyst. The catalyst has the advantages of good grain shape, high loading quantity and high activity, does not fall off the carrier and is suitable for vapor phase polymerization technology, slurry polymerization technology or combination polymerization technology.

The invention provides a transition metal single-atom catalyst. In the catalyst, transition metal single atoms are taken as active ingredients, carbon black is taken as a carrier, the loading capacityof the transition metal single atoms is 0.5-6wt%, and the highest loading capacity of the transition metal single atoms is higher than that of the prior art by 2-3 times. Various low-price transitionmetal single-atom catalysts with high dispersibility and high loading capacity are formed by inducing a limit range and by taking phenanthroline with strong complexation effect as a ligand and takingthe carbon black with high conductivity and high surface activity as the carrier. A preparation method of the transition metal single-atom catalyst has universality and can be used for preparing various low-price transition metal single-atom catalysts; according to the method, a Cr single-atom catalyst, an Nb single-atom catalyst, an Rh single-atom catalyst, a Cd single-atom catalyst, an Os single-atom catalyst and an Ir single-atom catalyst are prepared for the first time. Additionally, the preparation method has the advantages of being low in cost and simple in process and achieving large-scale production. Next, the catalyst has higher selectivity and Faraday efficiency in application of preparation of carbon monoxide by reducing carbon dioxide through electro-catalysis.

The invention relates to a monoatomic dispersed platinum group metal based catalyst with a higher loading capacity and an application of the catalyst. Specifically, the invention relates to a bicomponent catalyst of titanium oxide and one selected from metals rhodium (Rh), ruthenium (Ru), platinum (Pt), iridium (Ir) and palladium (Pd) as well as preparation and an application of the catalyst. Themetal is highly dispersed in the form of a single atom on the carrier titanium oxide, and the metal content is up to 0.4-2%. The catalyst provided by the invention is suitable for the CO water gas shift reaction, and can improve the CO conversion rate and inhibit a methanation side reaction; and meanwhile, the catalyst also has very good low-temperature activity and use stability on catalytic decomposition of the liquid single-component propellant level anhydrous hydrazine used in a satellite attitude control engine in the aerospace industry.