Described herein are hydrogel-coated surgical meshes and their use in
hernia repair,
reconstructive surgery, and other
surgical procedures. In one aspect, the hydrogel-coated meshes comprise at least one antibiotic or
antimicrobial agent for the treatment of
hernia repair
surgery. In one aspect, the hydrogel coated meshes provide localized, sustained
antimicrobial activity for the treatment of
surgical site infections. In one aspect, the hydrogel coated meshes provide localized, sustained prophylactic
antimicrobial activity for the prevention of
surgical site infections. In another aspect, the
hydrogel coating may optionally include one or more additional therapeutic components, such as anti-inflammatory compounds or growth factors, to facilitate and enhance
recovery following
hernia repair, reconstructive procedures, or other surgeries.