2349 results about "Drug" patented technology

The invention discloses a drug use dynamic risk assessment method and system for an elderly patient, and relates to the technical field of drug use risk assessment, and the method comprises the steps: collecting static factor data and dynamic factor data of the elderly patient, carrying out the preprocessing of the collected static factor data and dynamic factor data, and generating a feature vector for risk assessment; calculating a comprehensive risk score through a preset evaluation rule based on the feature vector; the comprehensive risk score is compared with a preset risk grading threshold value, the medication compliance risk grade of the elderly patient is determined, and the system comprises a data collection module, a preprocessing module, a risk assessment module and a grading module. The comprehensiveness and timeliness of medication compliance risk assessment of elderly patients are improved, and technical support is provided for medication intervention.

The embodiment of the invention discloses a medication answering method and device, electronic equipment and a storage medium. The method comprises the steps of obtaining a to-be-answered medication question, a knowledge base associated with the medication question and a large language model which is obtained by learning at least one candidate prompt word in advance and has a medication answering function; identifying a question category to which the medication question belongs, and determining a preliminary cue word matched with the question category in the at least one candidate cue word; according to the knowledge base and the medication problem, adjusting the preliminary cue word to obtain a target cue word; and inputting the target cue word into the large language model, so as to generate a drug use answer for solving the drug use problem according to the large language model and based on the target cue word. According to the technical scheme provided by the embodiment of the invention, the knowledge base is embedded into the large language model, so that the professionality of the medication solution generated by the large language model is improved by utilizing the knowledge base, and the accurate solution of the medication problem is ensured.

The invention discloses a drug-loaded liposome nano-particle, a preparation method thereof and application of the drug-loaded liposome nano-particle in treatment of brain glioma, and belongs to the technical field of biological nano-medicines. The invention provides a novel copper phthalocyanine derivative and catalase co-loaded lipidosome nanoparticle and application of the novel copper phthalocyanine derivative and catalase co-loaded lipidosome nanoparticle to treatment of brain glioma on the cellular level. The nano-particles are obtained by wrapping copper phthalocyanine derivatives and catalase with lipidosome prepared by a microfluidic method. The co-drug-loaded liposome can catalyze excessive H2O2 in brain glioma to generate oxygen, and O2 is continuously supplied to photodynamic therapy (PDT) to generate active oxygen; meanwhile, Cu < 2 + > can deplete glutathione and improve the oxidative stress level in the glioma, the reduction product Cu < + > can convert H2O2 into hydroxyl radicals with higher toxicity through a Fenton-like reaction, oxidative stress injury is doubly amplified, cascade cooperation of PDT and chemical dynamic therapy (CDT) is achieved, and the treatment effect on the glioma is remarkably enhanced.

The invention relates to the technical field of medical apparatus and instruments, and discloses a long-acting gastric retention drug delivery device which can enter the stomach in an oral self-ingestion mode, further realizes size change through expansion of an elastic assembly, enhances the mechanical strength of the elastic assembly through a water-induced hard polymer, and avoids extrusion deformation and emptying through the pylorus of the stomach. The device comprises a medicine carrying assembly, an elastic assembly and a connecting assembly, the medicine carrying assembly comprises a plurality of medicine carrying pieces, and each medicine carrying piece is provided with a medicine carrying cavity. The elastic assembly comprises a plurality of elastic pieces, and the first ends of the elastic pieces are connected with one another, so that the elastic assembly is in a star shape in the unfolded state. The outer layer of the elastic assembly is coated with a reinforcing film, and the reinforcing film is formed by curing a water-hardened polymer and can be gradually converted into rigidity from flexibility in a water-based environment. The connecting assembly comprises a plurality of connecting pieces, the second end of one elastic piece is connected with one medicine carrying piece through one connecting piece, and the connecting pieces are decomposed under preset conditions, so that the medicine carrying pieces and the elastic assembly are separated and discharged out of the body in a non-invasive mode.

The present invention relates to N-palmitoyl ethanolamide for the treatment of inflammatory pain in combination with a non-steroidal anti-inflammatory drug, to the use of N-palmitoyl ethanolamide (referred to as palmitoyl ethanolamide or PEA) in combination with a non-steroidal anti-inflammatory drug for the treatment of inflammatory pain. Specifically, the present invention relates to palmitoyl ethanolamide for use in the treatment of inflammatory pain, in particular non-neurological inflammatory pain, in which palmitoyl ethanolamide is administered in combination or in combination with a non-steroidal anti-inflammatory drug as needed, in which the administration is separate, combined or simultaneous.

The invention discloses an enantiokaurane compound with antitumor activity as well as a preparation method and application of the enantiokaurane compound. According to the present invention, chemical components of Western African plant I.trichantha tubers are deeply studied, and a variety of chromatographic separation methods such as macroporous resin, silica gel resin, medium pressure preparation-MCI column, gel normal pressure column and semi-preparative high performance liquid chromatography are combined to separate to obtain one enantiokaurane new compound Trichanthone B; experiments show that the compound obtained through separation has a good inhibition effect on an MIA PaCa-2 pancreatic cancer cell line and an A549 lung cancer cell line, and IC50 of the compound on the MIA PaCa-2 pancreatic cancer cell line reaches a nanomole level; the effect of the compound is stronger than that of positive drugs 5-fluorouracil and carboplatin, and the compound has the potential of being developed into new drugs for resisting pancreatic cancer and lung cancer.

The invention discloses an edible and medicinal composition for dispelling effects of alcohol and protecting liver as well as a preparation method and application thereof, and belongs to the technical field of functional foods. The composition consists of the following raw materials in parts by weight: 1-8 parts of ampelopsis grossedentata extract freeze-dried powder, 1-8 parts of astragalus membranaceus extract freeze-dried powder, 1-5 parts of kudzu vine root extract freeze-dried powder, 1-8 parts of hawthorn extract freeze-dried powder and 1-5 parts of cassia seed extract freeze-dried powder. The composition is designed according to a multi-component synergistic interaction principle, and the functions of protecting the liver and dispelling the effects of alcohol are enhanced through targeted interaction of active ingredients such as ampelopsis grossedentata flavone, puerarin and astragaloside; the compound preparation has the compound effects of protecting the liver, dispelling the effects of alcohol, resolving dampness, resisting oxidative stress, regulating lipid metabolism and the like, can remarkably relieve the problems of acute and chronic liver injury and metabolic disorder caused by alcohol intake, and meets the food-grade safety standard and the medicinal activity requirement; the important application prospect is realized in the aspect of preparing a preparation for relieving alcoholic liver injury and improving the liver detoxification function.

The invention relates to the technical field of biology, in particular to glycopeptide antibiotic and application thereof. According to the invention, a biosynthetic gene cluster for synthesizing a brand new glycopeptide antibiotic skeleton is excavated, and brand new glycopeptide antibiotics Varsomycin A, B and C with novel chemical structures are obtained through heterologous expression; the traditional Chinese medicine composition has a remarkable antibacterial effect on clinically drug-resistant strains. Important fermentation strains and precursor compound molecules are provided for research and development of new drugs of glycopeptide antibiotics, and important application prospects and economic values are achieved.

The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine preparation for treating Parkinson's disease and a preparation method thereof. The traditional Chinese medicine preparation for treating Parkinson's disease comprises the following raw materials in parts by weight: 20-30 parts of bischofia polycarpa, 17-25 parts of eucommia ulmoides, 12-16 parts of artemisia sphaerocephala, 10-15 parts of lycopodium clavatum, 8-13 parts of elm leaves, 7-14 parts of pericarpium citri reticulatae, 5-10 parts of semen cuscutae and 2-7 parts of liquorice. In the formula, monarch, minister, assistant and guide are reasonably matched, the curative effect is exact, and the effects of regulating qi and blood, nourishing liver, warming kidney, activating blood and dissipating blood stasis are achieved. The compound can effectively improve core symptoms of Parkinson's disease and delay disease progression, is expected to be further developed into clinical drugs for treatment of Parkinson's disease, and provides an innovative scheme for traditional Chinese medicine treatment of neurodegenerative diseases.

Exemplary olfactory delivery scaffolds may include 1) an olfactory targeting component, stimulant, or odorant that is recognized by the olfactory nerves via, for example, a smell response, 2) a molecule with biological activity, a therapeutic component, and / or drug (sometimes collectively referred to herein as a “therapeutic component”), and 3) a linker component that links the olfactory targeting component and therapeutic component together. The olfactory delivery scaffolds may be used to deliver a molecule with biological activity and / or a therapeutic component to a subject's neurological system through the olfactory pathway and pharmaceutical compositions useful in the treatment of neurological and / or neurodegenerative diseases.

The invention provides glycyrrhizic acid / glycyrrhetinic acid-triethanolamine composite hydrogel as well as a preparation method and application thereof, and belongs to the technical field of preparation of biological medicine carriers and composite materials. According to the invention, glycyrrhizic acid or glycyrrhetinic acid is taken as a raw material, triethanolamine is taken as a cross-linking regulating agent, and the composite hydrogel with stable mechanical properties, high drug loading efficiency and anti-inflammatory synergistic activity is prepared through a mild physical and chemical cross-linking reaction; the preparation process of the composite hydrogel does not need a toxic cross-linking agent, the reaction condition is mild, the raw materials are cheap and easy to obtain, and large-scale production can be realized; the composite hydrogel presents a multi-group ionic bond cross-linked structure, can be used as a carrier of a pH responsive drug, and has good practicability.

The invention relates to the field of traditional Chinese medicine compositions, in particular to a composition for dispelling effects of alcohol and protecting liver and application. The composition for dispelling the effects of alcohol and protecting the liver comprises the following raw materials: 1-4 parts of calculus bovis factitius, 1-4 parts of artificial bear gall, 35-55 parts of a pseudo-ginseng extract, 40-60 parts of a herba artemisiae scopariae extract, 50-70 parts of a rhizoma smilacis glabrae extract, 30-50 parts of a polygonum cuspidatum extract, 30-50 parts of a radix paeoniae alba extract, 70-90 parts of a pueraria flower extract, 40-60 parts of a rhizoma polygonati extract and 40-60 parts of a dark malt extract. And 25-35 parts of a fructus amomi extract. The hangover-alleviating and liver-protecting composition has the advantages that the hangover-alleviating and liver-protecting effects are similar to that of a positive medicine Haiwang Jinvessel for relieving rat body mass reduction caused by an acute drunkenness model, the hangover-alleviating rate within 6 hours and the liver-protecting and anti-oxidation effects are similar to that of a positive medicine Haiwang Jinvessel, the body mass improvement effect, the hangover-alleviating rate and the anti-oxidation capability of a body are better, and the hangover-alleviating and liver-protecting composition has good development and application values.

The invention relates to the technical field of micro-nano robots, and provides a motion control method and system for a magnetic control micro-nano robot carrying medicine in a simulation environment, and the method comprises the steps: obtaining a motion image of a magnetic control silicon dioxide-based micro-nano robot cluster in the simulation environment in real time; according to a preset transportation task, the current state of the micro-nano robot cluster is judged; based on the current state of the micro-nano robot cluster, establishing a magnetic field generated by the micro-nano robot cluster and the three-dimensional Helmholtz coil, a fluid resistance field of a simulation environment and a dynamic model of a simulation environment channel boundary condition; and based on the motion image acquired in real time, using a deep learning model to identify real-time pose information of the micro-nano robot cluster and the simulated environment channel boundary information, and using a path planning algorithm to perform trajectory planning according to the real-time pose information and the simulated environment channel boundary information. And the magnetic field is adjusted to control the movement of the micro-nano robot cluster.

The invention discloses a high-utilization-rate ginseng active ingredient medicinal preparation and a preparation method thereof, and relates to the technical field of medicines. The high-utilization-rate ginseng active ingredient pharmaceutical preparation is prepared from chitosan coated drug-loaded porous silicon dioxide composite nanoparticles and a drug-loaded MIL-101 metal organic framework matrix material, chitosan-coated drug-loading porous silicon dioxide composite nanoparticles are loaded on the surface of a drug-loading MIL-101 metal organic framework base material, and sodium alginate and a chitosan gel material are subjected to cross-linking connection, so that independent coating is formed, the framework base material and the composite nanoparticles are connected into a whole, the encapsulation performance and the drug loading capacity are improved, and the drug-loading capacity of the drug-loading MIL-101 metal organic framework composite nanoparticles is improved. Furthermore, the loading and the loading stability of the ginsenoside are improved, the adverse effects of gastric juice and gastrointestinal peristalsis on the activity of the ginsenoside are effectively reduced, the release and the absorption of the ginsenoside in intestinal tracts are remarkably enhanced, and the bioavailability is relatively high.

The invention particularly relates to a curcumin delivery system based on small extracellular vesicles, a preparation method and application. Curcumin has the defects of poor water solubility, poor chemical stability and insufficient targeting, in order to improve the bioavailability of curcumin, the curcumin delivery system based on small extracellular vesicles provided by the invention adopts RGD peptide surface modified sEVs as a carrier to coat curcumin, and saponin is used for assisting ultrasonic drug loading, so that the drug loading rate of curcumin is improved. According to verification of the invention, the delivery system can effectively improve the in-vitro release performance of the curcumin preparation and realize controlled release and slow release. Meanwhile, the delivery system effectively improves apoptosis induction of curcumin to glioma cells, the blood-brain barrier penetrating capacity of the curcumin delivery system is improved, and the treatment effect on brain glioma is expected to be improved.

The invention relates to the technical field of block chains, and provides a food and drug-oriented block chain anti-counterfeiting traceability method and system, and the method comprises the following steps: S1, embedding interference fringes with encrypted information in a color image, and generating an optical encrypted image of a product; s2, dynamically binding the phase mode of the optically encrypted image with the hash value of the product of each block chain node; and S3, verifying the product based on the physical characteristics of the optical encryption image and the dynamic binding relationship between the phase mode of the optical encryption image and the block chain node. According to the invention, the technical problems of easy copying of physical labels, many forbidden scenes, high risk of data tampering, insufficient dynamic anti-counterfeiting capability and lagging of channel conflict detection in food and drug circulation are solved, dual interlocking verification of physical characteristics and digital characteristics is realized, real-time credible tracing of full links of food and drug production, circulation and consumption is ensured, and the product quality is improved. And a safe, reliable, flexible and universal anti-counterfeiting tracing solution is provided for the food and medicine industry.

The invention discloses an anti-CLDN6 nano antibody and related application thereof, and relates to the field of antibodies. The invention provides an anti-CLDN6 nano antibody, which comprises HCDR1, HCDR2 and HCDR3 in a heavy chain variable region of which the amino acid sequence is as shown in SEQ ID NO: 4, the nano antibody has excellent antigen binding activity, high specificity and good affinity, has relatively strong killing activity on cells with high expression of CLDN6, and can be used for preparing anti-CLDN6 drugs. The requirements of CLDN6 positive tumor immunotherapy on efficient, specific and high-penetrability antibody molecules are met, and a new strategy and means are provided for tumor therapy.

The invention provides an anti-NKG2A antibody or an antigen binding fragment thereof and application of the anti-NKG2A antibody or the antigen binding fragment thereof. The antibody or the antigen binding fragment thereof comprises VH-CDR1, VH-CDR2, VH-CDR3, VL-CDR1, VL-CDR2 and VL-CDR3. The antibody or the antigen binding fragment thereof has the potential of treating tumors, and provides a choice for clinical tumor immunotherapy medication.

The invention provides a compound probiotic for relieving acute lung injury and application of the compound probiotic, and particularly discloses application of the compound probiotic consisting of bifidobacterium animalis YRK-12 and lactobacillus rhamnosus LRa-Y8 in preparation of a medicine for relieving the acute lung injury. Wherein the preservation number of the bifidobacterium animalis YRK-12 is CGMCC (China General Microbiological Culture Collection Center) No.28597; the preservation number of the lactobacillus rhamnosus LRa-Y8 is CGMCC (China General Microbiological Culture Collection Center) No. 34186. Experimental verification shows that the compound probiotics can remarkably relieve acute lung injury induced by lipopolysaccharide (LPS) through a synergistic effect; specifically, the weight loss rate of mice is reduced, pathological injuries of lung tissues are improved (the structural integrity of alveolar alveoli is maintained, and inflammatory cell infiltration is reduced), the levels of proinflammatory factors (IL-1beta, TNF-alpha and IL-6) in serum and lung tissues are reduced, and the level of anti-inflammatory factors (IL-4) is increased, so that the immune balance of the lung is regulated through an intestine-lung axis; and a safe and effective novel micro-ecological regulation strategy is provided for prevention and treatment of acute lung injury.

The invention relates to the technical field of extraction and separation of compounds in traditional Chinese medicinal materials, in particular to a method for simultaneously separating and purifying three pentacyclic triterpenoids from a tripterygium hypoglaucum root medicinal material. Three pentacyclic triterpenoid monomers are obtained through the steps of smashing, reflux extraction, normal-phase silica gel chromatography, reversed-phase high-pressure column chromatography, recrystallization and the like, the method is high in extraction efficiency and small in reagent dosage, the three pentacyclic triterpenoid compounds can be obtained at the same time, and the obtained compounds are high in purity and yield, have high social and economic value and are suitable for industrial production. The purity of the obtained plasmin, tripterine and demethylzeylasteral is high, and a foundation is laid for the preparation and production of reference substances of triterpenoid components in the roots of pyracantha fortunei, the subsequent pharmacological activity and the development of new immune drugs.

A GLP-1 receptor agonist having a structure of formula I, a pharmaceutically acceptable salt or a stereoisomer. Compared with LY3502970, the compound has excellent drug-like properties.

The present disclosure relates to the use of cannabidiol (CBD) for the treatment of atonic seizures. In particular the CBD appears particularly effective in reducing atonic seizures in patients suffering with etiologies that include: Lennox-Gastaut Syndrome; Tuberous Sclerosis Complex; Dravet Syndrome; Doose Syndrome; Aicardi syndrome; CDKL5 and Dup15q in comparison to other seizure types. The disclosure further relates to the use of CBD in combination with one or more anti-epileptic drugs (AEDs).

The invention relates to the technical field of medical instruments, in particular to an abnormal state grading response method based on a self-adaptive temperature control infusion pipeline, which comprises the following steps: S1, dynamic temperature threshold generation: calculating a dynamic temperature threshold interval through a temperature compensation model; s2, multi-parameter real-time monitoring: synchronously acquiring current temperature, flow velocity and pressure data in the infusion pipeline, and correcting a flow velocity value through a pressure fluctuation compensation algorithm; s3, abnormal state score calculation: generating an abnormal state score; s4, abnormal state grade judgment: the abnormal state is divided into first-level early warning, second-level intervention and third-level emergency shutdown; and S5, graded response execution: according to different grades of abnormal states, respectively triggering acousto-optic early warning, flow velocity adaptive adjustment, pipeline heating compensation or shutdown instructions. According to the invention, the continuity of the medication process of a patient is guaranteed, and clinical risks such as low-temperature mistaken transfusion, liquid medicine failure and abnormal flow velocity are reduced to the greatest extent.

The invention relates to the technical field of biochemical engineering, in particular to a medetomidine hapten, a preparation method of the medetomidine hapten, a medetomidine antigen, a preparation method of the medetomidine antigen, a kit and a medetomidine detection method. The medetomidine hapten is selected from a compound shown in the following structural formula: # imgabs0 #, q is any integer between 1 and 5, and R represents amido or carbonyl. The medetomidine hapten can be used for synthesizing a medetomidine antigen, so that the medetomidine hapten can be used for immunizing to generate an antibody, and adverse reaction caused by using medetomidine or hydrochloride thereof is reduced. Meanwhile, the medetomidine can be applied to rapid diagnosis products such as kits, medetomidine can be simply, conveniently and rapidly detected, and then the phenomenon of drug abuse can be effectively reduced.

The invention discloses a traditional Chinese medicine composition for preventing / treating systemic lupus erythematosus and application thereof.The traditional Chinese medicine composition is reasonably combined according to etiology and pathogenesis of systemic lupus erythematosus, pseudo-ginseng, ginseng, glossy privet fruit and syngnathus serve as monarch drugs, and the traditional Chinese medicine composition has the effects of promoting blood circulation to remove blood stasis, nourishing the liver and tonifying the kidney and directly tonifying yin deficiency of the liver and the kidney; salvia miltiorrhiza, safflower, peach kernel, American ginseng, codonopsis pilosula, prepared rhizome of rehmannia, wolfberry, mulberry and panax japonicus are taken as ministerial drugs and are matched to assist the monarch drugs and clear stasis heat, cornu cervi pantotrichum, herba epimedii, hippocampus, pericarpium citri reticulatae, polygonum multiflorum, angelica sinensis, radix paeoniae alba, rhizoma polygonati and dog kidney are taken as adjuvant and conductant drugs and assist the monarch and ministerial drugs to harmonize yin and yang, all the drugs are matched and have a synergistic effect, and the effects of nourishing kidney and replenishing essence, reinforcing qi and nourishing yin, promoting blood circulation to remove meridian obstruction, warming yang and removing stasis can be achieved. The traditional Chinese medicine can treat both symptoms and root causes, and can effectively treat systemic lupus erythematosus.

The invention discloses an adjustable flow limiter and an underwater chemical agent metering device.The flow limiter comprises a flow limiting base with a center through hole, a cylindrical component and an adjusting column capable of moving axially are fixedly installed in the center through hole, a spiral groove is formed in the outer wall of the adjusting column, one end of the spiral groove extends to form a liquid inlet, a liquid outlet is formed in the side portion of the cylindrical component, and the liquid outlet is communicated with the cylindrical component. The communication volume between the liquid inlet and the liquid outlet can be changed through axial movement of the adjusting column, accurate flow adjustment is achieved, the underwater chemical agent metering device comprises the flow limiter, a chemical agent inlet channel and a chemical agent outlet channel which are isolated from each other are arranged in the device shell, the chemical agent inlet channel is communicated with the liquid inlet of the flow limiter, and the chemical agent outlet channel is communicated with the liquid outlet. A first pressure transmitter and a second pressure transmitter are arranged in the device and used for monitoring the pressure of the medicine inlet channel and the pressure of the medicine outlet channel respectively, and the medicine flow is indirectly measured through pressure difference detection. The method has the beneficial effects that high-flow and high-precision adjustment is considered, the dynamic response is fast, and the reliability is high.

The invention relates to a double-framework self-developing embolism system based on iodine modified PNIPAM gel and cross-linked albumin microspheres, which simulates a brick wall-concrete effect through a microsphere-gel composite structure and synergistically improves the embolism strength. A novel TACE treatment system is designed and constructed, multiple effects of tracing, embolism, hypoxia enhanced chemotherapy and tumor microenvironment improvement are achieved through the self-developing temperature-sensitive gel-drug carrying microspheres, and the anti-tumor effect is cooperatively improved.

The invention discloses a preparation method of photo-thermal-MMP dual-response matrix hydrogel and application of the photo-thermal-MMP dual-response matrix hydrogel in diabetic wound repair, and belongs to the technical field of biological medicine. According to the present invention, the Cur (at) ZIF-8 (at) MMPDA / dAMG composite hydrogel is composed of an amnion source photo-crosslinked matrix hydrogel, curcumin-loaded ZIF-8 nanoparticles and MMP2 peptide modified polydopamine, and the Cur (at) ZIF-8 (at) MMPDA / dAMG composite hydrogel is obtained; the ZIF-8 nanoparticles decline in an acid environment to release zinc ions, destroy bacterial cell membranes, enhance the permeability of a biological membrane and cooperatively kill drug-resistant bacteria in combination with a photothermal effect, Cur is loaded through ZIF-8 to form Cur-coated ZIF-8, then a Cur-coated ZIF-8-coated MMPDA / dAMG double-drug-loading system is constructed through an MMPDA medium, and a photothermal antibacterial, anti-inflammatory and regeneration-promoting multi-mode therapy is formed for a wound surface in the acid environment. Therefore, wound healing is accelerated.

The invention discloses a dressing for promoting pain relief and regeneration of burn wounds and a preparation method of the dressing. The dressing comprises a drug delivery carrier and slow-release multi-effect hydrogel loaded on the drug delivery carrier, the slow-release multi-effect hydrogel is prepared from the following raw materials in parts by weight: 100 parts of water, 7 to 35 parts of multi-effect slow-release microspheres, 3.5 to 10 parts of sodium carboxymethyl cellulose, 2.5 to 8 parts of sodium hyaluronate and 0.5 to 4 parts of glycerol. The dressing provided by the invention has the effects of relieving wound pain, promoting wound regeneration and inhibiting and killing bacteria, the effect of the dressing is long-acting by realizing slow release of various active components (antibacterial carbon dots, silver nanoparticles and bletilla striata polysaccharide), and the dressing has a good application prospect by virtue of matching of the active components and the slow-release effect of the active components. The nursing and treatment effects of burn wounds can be effectively improved, and the application prospect is very good.

The invention provides a theaflavin composition for treating hypertension as well as a preparation method and application thereof, and relates to the technical field of medicines. The theaflavin composition comprises theaflavin, a celery seed extract, a gastrodia elata extract, a parasitic loranthus extract, a centella asiatica extract, a lotus leaf extract and a licorice extract. Wherein the theaflavin can regulate blood fat, inhibit atherosclerosis and improve the vascular endothelial function; the celery seed extract inhibits the activity of angiotensin converting enzyme, and cooperates with theaflavin to regulate blood pressure; the gastrodia elata extract can calm liver wind and improve cerebral circulation; the loranthus parasiticus extract has the effects of tonifying liver and kidney and regulating water sodium metabolism; the centella asiatica extract can resist inflammation and repair vascular endothelium; the lotus leaf extract can clear heat, promote diuresis, calm the liver and suppress yang; and the licorice extract harmonizes the medicines and resists oxidation. According to the invention, theaflavin is taken as a core, multi-dimensional effects of reducing blood pressure, protecting blood vessels and resisting inflammation and oxidation are realized, and a natural and comprehensive health management scheme is provided for hypertensive patients.