1073 results about "Biopolymer" patented technology

The invention discloses an immunoregulation hydrogel as well as a preparation method and application thereof, and relates to the technical field of medical materials, amino-derived cationic polysaccharide, carboxyl-derived anionic polysaccharide and dopa-modified protein biopolymer materials are used as biological matrix materials, spermidine is used as a bioactive functional component, and the immunoregulation hydrogel is prepared by a one-step method. The preparation method comprises the following steps: by taking a benzaldehyde-terminated high polymer material as a cross-linking agent, forming a first layer of dynamic reversible cross-linked network structure through Schiff base reaction; then calcium ions are introduced, and the calcium ions and carboxylate radicals are complexed and cross-linked to form a second layer of static irreversible cross-linked network structure which can be used for an ESD (Electro-Static Discharge) operation. By adopting a step-by-step cross-linking mode, the first-step cross-linked single-network hydrogel has injectability, self-repairability, tissue adhesiveness and an immune regulation function, and the second-step cross-linking further ensures stable and lasting performance, so that the problems that a submucosal injection material is easy to disperse, short in lasting time and poor in stability are solved. The immunoregulation function effect of the wound repair material is poor.

The invention relates to an emulsion from the oxidation products of natural waxes, having improved barrier properties, to a process of producing such an emulsion, and to cellulose fiber articles or biopolymers coated with such an emulsion from the oxidation products of natural waxes. The invention further relates to the use of such an emulsion for coating substrates that contain cellulose fibers or biopolymers.

The invention relates to a method for calculating molecular weight of a biological macromolecular material based on an AI algorithm. Part of biopolymer materials are difficult to form monomolecular chains after being dissolved into an aqueous solution, the ionic liquid is selected as a dissolution system, the monomolecular chains can be well formed after the macromolecular materials are dissolved, and then rheological data after biomacromolecules are dissolved in the ionic liquid are tested by using a rheological method. According to the method, a Rouse model is selected as a polymer solution model, and key parameter values are obtained by measuring a large amount of data, training the model by using an AI algorithm and carrying out nonlinear fitting, so that the molecular weight value of the measured material is calculated. The calculation method has the characteristics of accuracy and rapidness, and can be well popularized to the field of computer research of high polymer materials.

A biaxially oriented industrial or household compostable film web having at least three co-extruded layers selected from the group consisting of a facing film layer, a sealant film layer, and a combination of sealant film layers and facing film layers, wherein the sealant film layer and the surface film layer each comprise from 0 wt% to about 80 wt% of a polyhydroxyalkanoate (PHA) and from about 20 wt% to about 100 wt% of a polylactic acid (PLA), and optionally a small amount of a blend of other biopolymers, other polymers, nucleating agents, chain extenders, fatty amides, and fillers; and a core film layer comprising from about 30 wt% to about 80 wt% of a polyhydroxyalkanoate (PHA), from about 20 wt% to about 40 wt% of a polylactic acid (PLA), and optionally a small amount of a blend of other biopolymers, other polymers, nucleating agents, chain extenders, fatty amides, and fillers.

The present invention describes capsule compositions consisting of crosslinked chitosan, beta-glucan or alginate, and encapsulates an environmentally compatible insecticide, especially larvicidal agents such as essential oils or essential oil components or other ingestible larvicides such as Bacillus thuringiensis which are lethal to the larvae and adults of pest insects, especially mosquito larvae.

The invention belongs to the technical field of electrolyte materials, and particularly relates to a pH response biopolymer solid electrolyte as well as a preparation method and application thereof. The pH-responsive degradable biopolymer is taken as a main raw material, and one or more functional groups such as pyridine, sulfonic acid, carboxyl, tertiary amine, phosphoric acid and the like are contained. The organic acid and the organic acid salt are selected to adjust the pH value of a medium around the electrolyte, and the contraction / stretching behavior of a molecular chain is influenced by changing the ionization degree of the electrolyte, so that an interpenetrating polymer network structure is formed. The polar functional group of the biopolymer affects the migration behavior of lithium ions under different pH conditions, so that the migration rate and migration quantity of the lithium ions are increased, and the cycle performance of the battery is improved. The electrolyte is suitable for high-performance energy storage devices such as a lithium ion battery, can effectively improve the battery performance, reduces the environmental pollution, and has relatively strong green and environment-friendly advantages.

In some embodiments, methods and corresponding systems are disclosed for providing associated biopolymer sequence(s) to conform to a reference structure. The reference structure includes a target complex and the one or more associated biopolymer sequences. The biopolymer sequences are obtainable by the method, including embedding a graph representation using a neural network. The graph representation is featurized from the reference structure and includes a topology of the biopolymer with monomers as nodes and interactions between monomers as edges. The methods, in certain embodiments, further include processing the graph representation with a graph neural network or equivariant neural network that iteratively updates node and edge embeddings with a learned parametric function. The methods may further include converting the embedded graph representation to an energy landscape using a decoder. The methods can further include obtaining one or more biopolymer sequences from the energy landscape.

The invention provides a fabric-reinforced electroactive nerve conduit and a preparation method and application thereof, and belongs to the field of biomedical materials.The fabric-reinforced electroactive nerve conduit comprises a nerve conduit inner layer and a nerve conduit outer layer, the nerve conduit inner layer is a woven skeleton formed by magnesium wires serving as parallel yarns and degummed silk through a three-dimensional weaving process, the pore diameter of the nerve conduit inner layer is 1.5-2 mm, and the thickness of the nerve conduit inner layer is 0.5-1 mm; the outer layer of the nerve conduit is a composite layer with a radial finger-shaped porous structure, which is formed by directionally freezing and casting a hydrogel cross-linked network formed by mixing potassium sodium niobate nanorods modified by polydopamine and a biopolymer material, and the thickness of the outer layer of the nerve conduit is 1-2mm. A three-dimensional weaving technology, a piezoelectric nano material and a biopolymer material are combined, a novel multifunctional nerve conduit is developed to repair nerve injury, a better solution is provided for nerve repair, and the fabric enhanced electric activity nerve conduit has important practical guiding significance in application of future clinical nerve injury repair.

The invention relates to the field of electrolytes, and provides a gel electrolyte as well as a preparation method and application thereof in order to solve the problem of poor ionic conductivity of the gel electrolyte. The gel electrolyte comprises the following raw materials: a first polymeric monomer, a second polymeric monomer, an additive and a conductive lithium salt, the first polymeric monomer is a polyether acrylate monomer, the second polymeric monomer is an acrylamide monomer, and the additive is a biopolymer. According to the invention, the amide polymeric monomer is adopted to help dissolve the natural polymer, so that the natural polymer with poor solubility and processability but excellent inherent performance is used as an additive; the solubilizing monomer has no negative influence on the electrochemical performance of the electrolyte while improving the mechanical performance of the gel, and the introduced biomass-based additive has a large number of polar groups and can be coordinated with lithium ions, so that the ionic conductivity of the gel electrolyte is improved. The invention also provides a preparation method of the gel electrolyte and application of the gel electrolyte in a lithium ion battery.

The invention relates to the technical field of biopolymer materials, in particular to a preparation method and application of a cationic polymer gene vector with a fluorinated end group. The invention provides a cationic polymer with a fluorinated end group. The structure of the cationic polymer is shown in the specification. According to the method, a fluorinated group is introduced through a fluorinated initiator by a one-step method to initiate synthesis of various terminal group fluorinated linear polyethyleneimine F-PEI with different molecular weights, the gene transfection efficiency is improved by introduction of the fluorine group, and high-efficiency DNA transfection is realized. The gene vector can achieve an efficient transfection effect in the cell transfection process, the toxicity generated to cells in the transfection process is small, gene molecules can be effectively and safely conveyed into the cells, and the gene transfection vector has the advantages of being efficient, low in toxicity, low in price, easy to synthesize and the like. The method has the advantages of simple reaction, easily available raw materials, low preparation cost, easily controlled molecular weight, high yield and simple post-treatment, and is suitable for large-scale production. # imgabs0 #

The funeral coffin (1) for cremation comprises a plurality of boundary walls (2) made of a biopolymer material comprising: —one bottom wall (3); —a plurality of perimeter walls (4) defining, with the bottom wall (3), one internal volume (5) for the containment of one corpse; —one lid (6) intended to close the internal volume (5) at the top; wherein the biopolymer material is of a non-biodegradable type.

Talc particulate with specific physical properties having a particularly low migration factor when used as a filler in polymers is disclosed. Such talc particulates are of specific advantage as fillers in biopolymers, which are used as food contact materials (FCMs).

The invention discloses a gas separation membrane and a preparation method thereof, and belongs to the technical field of gas separation membranes. The gas separation membrane comprises a separation layer comprising a network and PTI nanosheets dispersed in the network, the network comprising at least one of a biopolymer network and a chemical polymer network; selectively, the device further comprises a supporting layer which is arranged below the separation layer and is combined with the separation layer. The preparation method of the gas separation membrane comprises the following step A or step B: step A: enabling raw materials of PTI nanosheets and networks to form a membrane on the surface of polymer hydrogel to obtain the gas separation membrane; and step B, enabling the PTI nanosheet and the network raw material to form a membrane on the surface of the material of the support layer to obtain the gas separation membrane. The gas separation membrane provided by the invention is an N2 preferential permeation membrane, and has relatively high N2 permeation rate and relatively high N2 / CO2 selectivity.

The invention belongs to the technical field of silk fibroin microspheres, and discloses a preparation method of silk fibroin nanospheres. Belongs to the technical field of biopolymer microsphere preparation, and the preparation method comprises the following steps: 1) adding a crystallization inducer into a silk fibroin solution, uniformly mixing, adding a dispersant into the solution, and mixing to obtain a pretreatment liquid; 2) carrying out low-temperature solidification treatment on the pretreatment liquid, and unfreezing to obtain a silk fibroin nanosphere suspension; 3) performing ultrasonic dispersion on the silk fibroin nanosphere suspension to obtain a silk fibroin nanosphere solution; and 4) centrifuging and freeze-drying the silk fibroin nanosphere liquid to obtain the solid silk fibroin nanosphere. The silk fibroin nanosphere obtained by the invention has the advantages of excellent biocompatibility, controllable size and good dispersity. The preparation method is simple and high in yield.

The invention discloses a multifunctional coating with a compact-porous double-layer structure on the surface of magnesium alloy and a preparation method, and belongs to the technical field of biological materials. According to the multifunctional coating, magnesium alloy serves as a substrate, a compact layer and a porous layer are sequentially stacked from the substrate to the outside, and the compact layer is composed of two-dimensional transition metal carbide / nitride, calcium silicate nanowires and a positively charged polymer. The porous layer is composed of copper-containing complex / biopolymer composite fibers, mineralized silk fibers loaded with bioactive metal ions and astragalus polysaccharide on the surface, and natural polymers. According to the multifunctional coating with the compact-porous double-layer structure prepared on the surface of the magnesium alloy, the porous layer on the surface layer has a unique porous structure, growth and proliferation of osteoblasts can be well promoted, meanwhile, the multifunctional coating has the characteristics of pressure resistance, bacteria resistance and oxidation resistance, the compact layer on the bottom layer can improve the corrosion resistance of the magnesium alloy, and the service life of the magnesium alloy is prolonged. The coating is particularly suitable for surface coating of magnesium alloy implant materials and can be used in the field of medical instruments.

Compositions and methods for filling tissue voids and defects with a self-assembling biopolymer configured to form a shape-retaining matrix are described.

Disclosed herein are methods of producing a scaffold by producing a biopolymer scaffold composition by pneumatospinning a polymer solution comprising polymer fibers onto a collector; feeding the polymer fiber solution comprising the polymer fiber into an air brush; applying a gas pressure around the polymer fiber solution comprising the polymer fiber in the airbrush; ejecting the polymer fiber from the air brush onto the collector; crosslinking the polymer fibers; and seeding a plurality of cells to the polymer scaffold composition.

Novel approaches for processing polymeric analytes, such as biopolymers, are provided herein. A method for processing a polymeric analyte may comprise coupling a monomer of the polymeric analyte to a capture moiety, cleaving the monomer from the polymeric analyte, and analyzing the cleaved monomer, e.g., using a binding agent. The methods described herein may employ the use of activating agents.

Edible microcarrier for growing anchorage-dependent cells to prepare a cultured meat product, where the edible microcarrier includes a microcarrier core and a microcarrier coating at least partially directly or indirectly covering the surface of said microcarrier core, wherein said microcarrier core is a hydrogel having only the following components: (A) 0.03-10.0 wt % of at least one ionically crosslinked polysaccharide; (B) 0.05-5 wt % of a mechanical stability agent different from (A); (C) 0.0-10 wt % of additives different from (A) and (B); (D) 0.0-50 wt % living cells; (E) 75-99.92 wt % of water; where the sum of (A)-(E) making up 100 wt %, and where the microcarrier coating includes a biopolymer, where the biopolymer is crosslinked using a crosslinking agent.

The invention belongs to the technical field of oilfield chemistry, and particularly relates to a degradable bio-based system for sand consolidation and profile control as well as a preparation method and application of the degradable bio-based system. The degradable bio-based system for sand consolidation and profile control is prepared from the following components in parts by weight: 15 to 25 parts of 1, 4: 3, 6-dianhydro-D-sorbitol / maleic anhydride biopolymer, 30 to 40 parts of resin, 10 to 15 parts of ethylene glycol dimethyl ether, 5 to 8 parts of flexibilizer, 10 to 12 parts of curing agent and the balance of water according to the total weight of 100 parts. The degradable bio-based system for sand consolidation and profile control provided by the invention not only has good sand consolidation performance and can solve the problem of sand production of a water well, but also has certain effects of blocking a high-permeability layer and adjusting the section of a reservoir near a water injection well, and has the functions of sand consolidation and profile control of the water well.

This invention discloses adhesive compositions useful for providing cohesive strength to particles, for example a mat of wood particles produced while making particleboard prior to curing. The adhesive compositions has a) one or more biopolymers and b) one or more monomers or oligomers. An oligomer may have a degree of polymerization of 4 or less. The weight ratio of the monomer / oligomer to the biopolymer is optionally between 30:70 and 80:20. Optionally, the adhesive compositions may be combined with an isocyanate. The adhesive composition may be used to make no added formaldehyde wood composites such as particleboard.

The present disclosure generally relates to compositions and methods of simultaneously making two unique biointermediates from a single lignocellulosic biomass feedstock, including a hydrophobic biohydrocarbon and a water insoluble hydrophilic cellulosic biopolymer for use in the production of renewable fuels, chemicals, and other carbon neutral materials commonly derived from petroleum and other fossil resources.

The present invention relates to methods of manufacturing beverage capsules, the method comprising: (a) providing a biopolymer film, wherein the biopolymer film comprises a layered structure comprising biopolymer layer - polyglycolide (PGA) layer - biopolymer layer; and (b) thermoforming the biopolymer film to form at least one layer of a capsule body comprising or consisting of the biopolymer film.

Method for generating a porous injectable scaffold that includes providing a liquid composition of 2 phases at a temperature below 25° C., of Newtonian behavior, where the composition comprises:a liquid dispersant phase at room temperature formed by a gelatin with a low melting point, less than 15° C., functionalized with methacryloyl or methacrylamide groups; and a photoinitiator;and a dispersed phase, of microdroplets or beads in solid state, of a gelatin solution with a melting point greater than 25° C.;initiating the polymerization of the dispersing phase by light radiation; raising the temperature to 35-40° C. and allowing melting of the dispersed phase; and obtaining a porous scaffold.The formed porous scaffold and its use as a biological support for tissue regeneration / generation; as a biological matrix as a support for cells, for cell invasion; as an acellular biological matrix, a biological matrix as a mechanical support and / or a biological matrix for active components.

A biaxially oriented cavitated PHA-rich composite film comprises a PHA-rich core layer and a first outer skin layer and a second outer skin layer. The core layer comprises a PHA resin at an amount of more than 50 wt % of a total weight of the polymeric resin in the core layer and a modifier X, the modifier X includes PLA resins and PLA copolymers and at least one mineral inorganic cavitating agent; the first outer skin layer comprises a PLA resin at an amount less than 50 wt % of the total weight of the outer layer and biopolymers comprising PHA resins or PBSA resins or PCL resins or mixture thereof. The PHA-rich composite film shows a reduced film density and higher yield as well as low light transmission rate.

The invention relates to a microneedle patch, a preparation method thereof and a blood glucose colorimetric detection method, and belongs to the technical field of biomedicine. The microneedle patch comprises a needle tip layer and a backing layer, the needle tip layer is a methacrylated natural biopolymer matrix in which immobilized enzyme is uniformly distributed, and the backing layer is a methacrylated natural biopolymer matrix in which a chromogenic substrate is uniformly distributed, the immobilized enzyme is composed of a zinc-based imidazoline metal organic framework MAF-7 carrier and a natural enzyme loaded in the framework. The immobilized enzyme with double-enzyme activity is loaded into the needle tip, the spatial distance of the cascade catalytic reaction is limited in the metal organic framework, the mass transfer efficiency is high, the reaction is rapid, the natural enzyme is encapsulated in the metal organic framework MAF-7, and the stability of the enzyme is enhanced; according to the method, color development is carried out by firstly extracting the interstitial fluid and then dropwise adding the color development substrate, the color development effect is obvious, and the time is shorter.

Disclosed is a modified biopolymer having the formula A-XY wherein: (a) A is a starting material selected from the group consisting of a polysaccharide, a protein and a cellulose; (b) X is a first moiety bearing a functionality co-reactive with A; (c) Y is a second moiety covalently bound to X, capable of undergoing free radical polymerization and bearing at least two ethylenically unsaturated functional groups; (d) the starting material A and the first moiety X are linked covalently through linkages selected from the group consisting of an ester, an amide, a urethane, a urea, a sulfonate ester, a phosphate ester and an ether; and (e) a degree of substitution of the starting material A with the first moiety X is less than 0.5 but more than 0.1. Compositions including the modified biopolymer and methods for making them are also disclosed.

The invention described herein relates to novel, non-naturally occurring, elastic, animal-component-free recombinant fusion biopolymers produced in plants by transient expression. More specifically, the present invention describes polynucleotides encoding fusion proteins of non-human sclerostin and human collagen wherein the fusion proteins are capable of forming hydroxylated triple helix fibers. The fusion protein is especially a fusion protein of spider silk protein-like protein and human collagen. More particularly, the present invention relates to a spider silk protein I / I type collagen fusion protein capable of forming a hydroxylated triple helix fiber, or a silk fibroin III / I type collagen fusion protein capable of forming a hydroxylated triple helix fiber. The present invention has improved properties (e.g., thermal stability, Young's modulus, cell adhesion, degradability, etc.) compared to native type I collagen. The invention also describes a method of use thereof, such as as defined in the claims for use as an electrospun scaffold particularly suitable for biomedical or cosmetic applications.

The invention discloses terahertz regulation and control conductive aerogel and a preparation method and application thereof.The preparation method comprises the following steps that mixed precursor dispersion liquid of cellulose nanofibers, sodium alginate and conductive filler is prepared; the mixed precursor dispersion liquid is poured into a mold, the mold is immersed into liquid nitrogen, temperature gradients in the vertical direction and the horizontal direction are formed in the mixed precursor dispersion liquid, bidirectional freezing is carried out, and growth of layered ice crystals in the parallel direction in the mixed precursor dispersion liquid is promoted; after bidirectional freezing is completed, freeze drying is conducted, and the product is obtained. The layered and high-porosity aerogel is assembled through a simple and convenient two-way freeze drying process, and the biopolymer aerogel has large-scale and parallel-oriented micron-sized pores and shows excellent mechanical strength, flexibility and elasticity. The conductivity of the aerogel can be changed by compressing the aerogel, so that the terahertz performance, including birefringence and absorption characteristics, of the aerogel can be intelligently regulated and controlled.

The invention discloses a preparation method of a sand washing mud-based pressed product, which comprises the following steps: carrying out semi-dry dehydration on sand washing mud until the water content is 15-20%, and then mixing the sand washing mud with biopolymer powder to obtain a premix, the biopolymer powder comprises cationic polymer powder and anionic polymer powder; loading the premix into a mold, and carrying out compression molding to obtain a pressed product mold blank; and activating the pressed product mold blank by using microwaves to obtain the sand washing mud-based pressed product. Therefore, the pressed product prepared by the preparation method disclosed by the invention has the advantages of high forming speed, high compressive strength and no need of a long-time autoclaved activation process, the forming period is greatly prolonged, and the large-scale yield is favorably increased. The raw materials are rich in source, solid waste resource utilization of the sand washing mud can be achieved, waste is turned into wealth, and the environmental burden is reduced.