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1205results about "Surgical veterinary" patented technology

Equipment for building abdominal organ trauma model of small rodent

The invention provides equipment for building a small rodent abdominal organ trauma model, and belongs to the technical field of animal model building. Comprising a base table, an experiment table, two groups of vertical plates and transverse plates, an impact mechanism; the impact mechanism comprises a connecting rod which is movably arranged at the top of the transverse plate and extends to the bottom of the transverse plate, and scale marks are arranged on the surface of the connecting rod; the impact mechanism is arranged, before an experiment, a gear can be driven to be separated from a limiting clamping block but still engaged with clamping teeth by pulling a control rod, at the moment, a connecting rod can be driven to move downwards through the clamping teeth by rotating the gear, a bottom plate is driven to move downwards through movement of the connecting rod, and the compression force of a driving spring can be reduced; therefore, the impact force of the animal in the impact experiment is adjusted, the experimental data can be visually recorded by observing the scale marks, and the force applied by an operator in the impact experiment can be more effectively controlled through the cooperation of the parts.
Owner:THE THIRD MEDICAL CENT OF THE CHINESE PEOPLES LIBERATION ARMY GENERAL HOSPITAL

Animal craniocerebral injury model construction method and system

The invention relates to an animal craniocerebral injury model construction method and system, and the method comprises the following steps: 1, selecting a plurality of healthy male SD (Sprague Dawley) rats, breeding the rats in different cages in a 12-hour illumination environment and a 6-hour dark environment at the temperature of 25 DEG C, dividing the rats into three groups, and enabling the rats to eat and drink water; 2, the rats are divided into an X group, a Y group and a Z group through random grouping, the X group is a mild craniocerebral injury group, the Y group is a moderate craniocerebral injury group, the Z group is a severe craniocerebral injury group, and the number of the rats in each group is equal; according to the animal craniocerebral injury model, animal craniocerebral injury of different degrees can be simulated, the injury degree can be evaluated, and the model has good repeatability, reliability and stability and has good reference value in practical application.
Owner:THE 960TH HOSPITAL OF THE CHINESE PEOPLES LIBERATION ARMY JOINT LOGISTICS SUPPORT FORCE

Establishment method and application of mouse gastric cancer orthotopic transplantation model

The invention discloses an establishment method and application of a mouse gastric cancer orthotopic transplantation model, and the establishment method comprises the following steps: injecting a mouse gastric adenocarcinoma cell line MKC1 (Mus musculus) into a mouse gastric tissue, and feeding to obtain the mouse gastric cancer orthotopic transplantation model. Compared with the prior art, the mouse gastric cancer in-situ model established in the invention has the advantages of strong repeatability in the construction process and good passage stability, especially can form tumor subcutaneously in a C57BL / 6 mouse with a sound immune system, has a therapeutic response to immunotherapeutic drugs such as anti-PD-1 monoclonal antibody, and is suitable for research on gastric cancer immune microenvironment and drug resistance mechanism of immunotherapeutic drugs.
Owner:SHANDONG UNIV

Digitally-controlled extracranial strike construction equipment for traumatic brain injury model

The invention relates to the technical field of extracranial strike testing, in particular to digitally-controlled extracranial strike construction equipment of a traumatic brain injury model. Comprising a test platform, a sliding rail installed on the test platform and arranged in the length direction of the test platform, an animal fixing platform slidably connected with the test platform through the sliding rail, an impact structure arranged on one side of the test platform and a driving structure used for driving the animal fixing platform to move towards the impact structure. The impact structure is fixedly connected to the test platform, the output end of the impact structure faces the animal fixing platform, an experimental animal is installed on the animal fixing platform, the driving structure drives the animal fixing platform to enable the experimental animal to actively impact, and the impact structure enables the experimental animal to impact a fixed acting point at a certain initial speed. The system is more in line with the injury mechanism of a patient with clinical actual craniocerebral trauma, and a tester can accurately control and monitor parameters according to the moving speed and the moving distance of the animal fixing platform.
Owner:JIAXING NO 1 HOSPITAL

Tumor living body sampling device

The invention provides a tumor living body sampling device, and relates to the field of biological sampling, the tumor living body sampling device comprises: a sampler main body, the sampler main body is a pistol-shaped structure; the inner sampling needle is coaxially and rotatably connected to the inner side of the reversing seat, the inner sampling needle is rotatably connected to the inner side of the sampling outer cylinder, the right cross sections of the sampling outer cylinder and the inner sampling needle are of arch-shaped structures, and the right end parts of the sampling outer cylinder and the inner sampling needle are of needle-shaped spine structures; hollow sampling openings are formed in arch-shaped parts on the right sides of the sampling outer cylinder and the inner sampling needle; the sampling transmission assembly is arranged in the sampler main body, and the sampling operation block drives the sampling outer cylinder and the inner sampling needle to rotate reversely at the same time through the sampling transmission assembly. The tumor tissue is rapidly and completely cut off, tearing damage is avoided, samples are isolated from the tissue, the samples are prevented from being mixed, and the problems that in the existing sampling process, the tissue is difficult to effectively cut off, tissue tearing is easily caused, and tissue samples are not pure are solved.
Owner:SUZHOU HUATUO BIOTECHNOLOGY CO LTD

Construction method of model for rat traumatic brain injury caused by explosive shock waves

The invention belongs to the technical field of damage assessment, and particularly relates to a construction method of a rat traumatic brain injury model caused by explosive shock waves. By protecting other important visceral organs except the brain, interference of damage of visceral organs such as the lung to brain injury is avoided, the overall function stability of the body is maintained, the caused brain injury can more truly reflect the characteristics of explosive traumatic brain injury, and the credibility and repeatability of experimental data are improved. The construction method simulates loading of explosion shock wave parameters in a real environment, constructs an animal traumatic brain injury model through live ammunition explosion, is closer to an actual combat environment, and can truly reflect physical parameters related to explosion and a complex action process generated by interaction of the physical parameters. And a support is provided for developing molecular mechanisms of explosive traumatic brain injury, clinical diagnosis, screening of therapeutic drugs and the like.
Owner:ORDNANCE IND HYGIENIC INST

Method for establishing hypoperfusion cerebral infarction model

The invention discloses a method for establishing a hypoperfusion cerebral infarction model, which is used for simulating a clinical cerebral infarction animal model caused by low blood pressure by adopting a method for establishing a model for combining hypotension with improved middle cerebral artery occlusion (MCAO) rats. Compared with the prior art, the technical method that existing bilateral carotid artery ligation can only simulate chronic cerebral ischemia, ischemic infarction lesions are not formed, and hypoperfusion cerebral infarction cannot be simulated is broken through, the composite method that blood pressure reduction is combined with MCAO improvement is used for the first time, and the clinical common pathological state of cerebral blood flow hypoperfusion cerebral infarction caused by hypotension is simulated. According to the invention, the pathologic process of occurrence and development of the disease and the pharmacology of the drug are researched, and the drug action mechanism is explained; a reliable animal model is provided for new drug research and development.
Owner:DONGZHIMEN HOSPITAL OF BEIJING UNIV OF CHINESE MEDICINE

Test Fish Holding Device and Test Fish Treatment Method

Provided is a technology which can properly perform a predetermined treatment on an abdomen of a test fish while reliably holding the test fish in a predetermined posture by suppressing damage as much as possible. A test fish holding device includes a flexible holder, the holder having a holding groove extending along a front-rear direction on an upper surface side and internally holding the test fish loaded from an upper opening portion. The holder has a slit extending along the front-rear direction in a bottom portion of the holding groove and exposing the abdomen of the test fish held inside the holding groove through a lower surface side. A width of the slit is widened by generating a tensile force from an inside toward an outside on the lower surface side of the holder.
Owner:KOBELCO ECO SOLUTIONS CO LTD

Brain stereotaxic apparatus capable of adjusting U-shaped seat with multiple degrees of freedom

The invention discloses a brain stereotaxic instrument capable of adjusting a U-shaped seat with multiple degrees of freedom, and relates to the technical field of brain stereotaxic instruments. The device specifically comprises a bottom plate, the bottom of the bottom plate is fixedly connected with a foot pad, and the top of the bottom plate is provided with a front-back movement adjusting seat; the brain stereotaxic apparatus capable of adjusting the U-shaped base in the multi-degree-of-freedom mode further comprises a rotation adjusting mechanism used for adjusting the overall Z-axis swing angle of the operation workbench through rotation, the rotation adjusting mechanism is arranged at the top of the bottom plate, a bottom swing center shaft is installed at the top of the rotation platform, a calibration block is arranged at the top of the bottom swing center shaft, and the bottom swing center shaft is connected with the calibration block. The rotating platform is arranged at the top of the bottom plate, a swing angle support is arranged at the top of the rotating adjusting mechanism, and an operating table multi-angle adjusting mechanism is arranged outside the swing angle support; according to the brain stereotaxic instrument with the U-shaped seat capable of being adjusted in multiple degrees of freedom, the purpose of improving the use efficiency of equipment is achieved.
Owner:SUZHOU KUNYIN TECHNOLOGY CO LTD

Segmented cutting device and system for rumen fistula

The invention relates to a segmented cutting device and system for a rumen fistula. The segmented cutting device comprises a first handle unit, a second handle unit, a first baffle unit, a second baffle unit, a first cutting processing unit and a second cutting processing unit. The device has the advantages that a stable holding point is provided for an operator through cooperative use of the first handle unit and the second handle unit, the whole device is convenient to control, accurate operation is facilitated, misoperation caused by unstable holding is avoided, and the risk of accidentally injuring dairy cows is reduced; the first baffle unit and the second baffle unit are used in cooperation and can abut against the fistula inner wall and the fistula outer wall, a cutting area can be isolated from surrounding dairy cow tissue, the protection effect is achieved, contact between a cutter and other tissue is reduced, the risk of injury to other parts of the dairy cow body is reduced, the cutting position is accurately limited, and the cutting efficiency is improved. The cutter is prevented from deviating from the preset position in the cutting process.
Owner:SHANGHAI BRIGHT HOLSTAN CO LTD

Pig farm breeding and breeding vehicle

The utility model discloses a pig farm breeding and breeding vehicle which comprises a frame formed by welding square pipes, the frame is provided with an operation layer, a first storage layer and a second storage layer from top to bottom, a side plate of the operation layer is fixedly provided with a fixing plate through a five-star handle, and the fixing plate is provided with a tail breaking device. And a castrating bracket mounted on the other side plate of the operation layer is arranged in front of the tail cutter. The tail cutting device and the castration support are arranged, tail cutting and castration can be achieved on one device, convenience and rapidness are achieved, various nursing behaviors can be completed at a time, meanwhile, tools and operation space used for immune behaviors are provided, rework is avoided, the manual workload is reduced, and artificial counterfeiting is eradicated.
Owner:NANJING HAIKE TECH CO LTD

Construction method for myocardial ischemia animal model

The invention relates to the technical field of animal experiments, and discloses a method for constructing a myocardial ischemia animal model, which comprises the following steps: calculating morphological characteristics of contrast mesenchymal stem cells in a preprocessed image, carrying out principal component analysis on the morphological characteristics, and outputting cell activity corresponding to the principal component through an activity analysis model; the method comprises the following steps: constructing an animal three-dimensional model of a myocardial injury animal, and collecting a culture environment of experimental mesenchymal stem cells; the method comprises the following steps: selecting a growth environment in a myocardial injury animal by utilizing a culture environment, collecting an environment image of the growth environment, and selecting a transplantation position of the myocardial injury animal from the environment image; and determining a three-dimensional position of a transplantation position from the animal three-dimensional model, constructing a transplantation path from the surface position to the three-dimensional position of the animal three-dimensional model, and transplanting the experimental mesenchymal stem cells to the transplantation position to obtain the orthotopic transplantation animal model. According to the invention, the cell activity recognition process capable of repairing myocardial injury can be realized, and sufficient growth space of cells is ensured.
Owner:GUANGDONG JINSHI MEDICAL TECH SERVICE CO LTD

Intelligent control method and system for irreversible electroporation regeneration of cartilage tissue

The invention discloses an intelligent control method and system for irreversible electroporation regeneration of cartilage tissue. The method comprises the following steps: selecting an experimental animal to establish an osteoarthritis model, and carrying out quantitative analysis on the osteoarthritis model through an algorithm; designing and preparing a specific gene vector; performing an electroporation process to introduce the specific gene vector into the target cartilage tissue; monitoring gene transfection efficiency and expression level in real time, and dynamically adjusting electroporation parameters according to real-time monitoring data; the cartilage regeneration and function recovery conditions are evaluated through a multi-modal imaging and histological method; and performing comprehensive analysis based on an evaluation result, and dynamically adjusting an electroporation parameter and a gene transfection strategy. The system comprises an osteoarthritis model establishment module, a carrier design module, a carrier import module, a dynamic adjustment module, an image evaluation module and a comprehensive analysis module. According to the method, quantitative evaluation and dynamic feedback adjustment of the cartilage repair effect are realized through an algorithm and multi-modal data analysis.
Owner:TIANJIN YINGTAI LIANKANG MEDICAL SCI & TECH CO LTD +1

Flexible multi-channel implantable biological electrode, implantation device and method

The invention belongs to the technical field of biological electrodes, and particularly relates to a flexible multi-channel implantable biological electrode, an implanting device and a method, and the biological electrode is formed by fixing at least two single-channel electrodes into a bundle in a spiral winding or parallel fixing mode; adjacent single-channel electrodes abut against and are fixed and insulated from each other, the single-channel electrodes are respectively provided with exposure sites used for collecting electroneurographic signals and / or electromyographic signals or used for nerve electrical stimulation and / or electromyographic stimulation at the implantation sections, and the single-channel electrodes have determined relative positions and jointly form multiple channels; and the exposed sites are arranged at the end part and / or the side surface of the implantation section of the single-channel electrode. Compared with the prior art, the problem that each single-channel electrode in a'multi-channel 'biological electrode in the prior art does not have certain relevance is solved. According to the scheme, all the single-channel electrodes forming the flexible multi-channel biological electrode have a clear relative position relation, and electrode exposure point positions can be arranged at designated positions according to needs.
Owner:SHANGHAI JIAOTONG UNIV +1

Rat uterus scar diverticulum model preparation method, identification method and histopathologic analysis method

PendingCN120284517ASurgical veterinaryHuman uterusUterus incision
The invention relates to the technical field of biology and new medicine, in particular to a preparation method, an identification method and a histopathologic analysis method of a rat uterus scar diverticulum model. The preparation method of the rat uterus scar diverticulum model comprises the following steps: sequentially simulating rat pregnancy by using female progestational hormone, and infecting a uterus incision by using group B streptococcus (GBS) to obtain the rat uterus scar diverticulum model. The preparation method comprises the following steps: constructing a pseudopregnant rat model; preparing a GBS bacterial solution with a certain concentration, and immersing 3-0 silk threads with the length of about 1cm into the bacterial solution for 24 hours for later use; an incision with the length of about 2 cm is formed in the uterus on the two sides of the rat, and the incision is sutured discontinuously by an absorbable line. The simulated pregnant mouse is used, the influence of uterine hyperemia during human delivery and hormone change after female progestational hormone withdrawal on the uterine microenvironment is met, the formation of the human uterine scar diverticulum simulated by using the group B streptococcus infection incision is related to cesarean delivery incision infection, and therefore the success rate of the obtained model is high.
Owner:THE FIRST AFFILIATED HOSPITAL OF ANHUI MEDICAL UNIV

Ligature device and method of use

The present invention is an apparatus and method for ligation of livestock animals. The ligation apparatus or band provides topical active agent(s) that alleviate pain during various ligature procedures. This invention also relates to a method that includes applying a loop or band around a body part for elastomeric ligation, whereby the band material supplies a topical active agent (s) to the body part to reduce the pain of ligation.
Owner:CHINOOK CONTRACT RES INC

Methods of insect control for an animal, products thereof and methods for their preparation

ActiveUS20250017714A1BiocideOrganic active ingredientsAnimal scienceUmbilical cord knot
There is provided methods for insect control, including controlling myiasis, in animals by affixing to the animal an elastomeric band having infused or contained within an insecticide, an insect repellant, lidocaine, or any combination thereof. The insect control may be a dual-mode control and may be in respect of existing or impending open wounds, including open wounds caused by castration, tail docking, umbilical cord ligation, or dehorning of an animal. There is also provided methods for castration, docking, umbilical cord ligation, or dehorning of an animal with concurrent insect control. Also provided are elastomeric bands for insect control and methods for preparing such elastomeric bands.
Owner:CHINOOK CONTRACT RES INC

Rat caudal vertebra intervertebral disc degeneration modeling device and method

The invention discloses a rat caudal vertebra intervertebral disc degeneration molding device which comprises an anesthesia box, a tail outlet hole is formed in the anesthesia box, a bearing table is arranged on the outer side of the anesthesia box, an arc-shaped locking plate is slidably installed on the bearing table, a containing groove is formed between the arc-shaped locking plate and the bearing table, and a sleeve is slidably installed on the arc-shaped locking plate in the circumferential direction; a puncture cylinder is in threaded connection with the interior of the sleeve, a graduated scale is axially arranged on the outer side wall of the puncture cylinder, a puncture needle is installed in the puncture cylinder and comprises a base and a needle head connected to the base, the base is installed in the puncture cylinder, the needle head sequentially penetrates through the puncture cylinder, the sleeve and the arc-shaped locking plate and then extends into the containing groove, and a bandage is arranged above the bearing table. An X-ray machine is arranged on the periphery of the bearing plate. The invention further discloses a rat caudal vertebra intervertebral disc degeneration modeling method using the rat caudal vertebra intervertebral disc degeneration modeling device. According to the rat caudal vertebra intervertebral disc degeneration modeling device and method, few tools are used, the process is simple, and application and popularization are convenient.
Owner:FIRST HOSPITAL AFFILIATED TO GENERAL HOSPITAL OF PLA

Rat thrombus forming device

The utility model discloses a rat thrombus forming device which comprises a blood collecting assembly and a thrombus forming assembly, the blood collecting assembly is used for collecting blood of a rat, and the blood collected by the blood collecting assembly is conveyed to the thrombus forming assembly to prepare thrombus; the blood sampling assembly comprises a bottom plate and a top plate, the top plate is located over the bottom plate, a vertical supporting rod is connected between the center of the bottom plate and the center of the top plate, the top plate can rotate around the supporting rod, a plurality of round holes are formed in the top plate in the annular direction, and blood collecting pipes are vertically placed in the round holes; a liquid outlet is formed in the bottom of the blood collecting pipe, a blood transfer pipe is connected to the liquid outlet, and the head end of the blood transfer pipe extends to the thrombus forming assembly; the thrombus forming assembly comprises a rectangular forming groove, a forming template made of rubber is fixed to the bottom of the forming groove, pits with honeycomb holes are densely distributed in the forming template, the diameter of each pit is 2-3 mm, and the depth of each pit is 2-3 mm.
Owner:GANSU UNIV OF CHINESE MEDICINE

Equipment for establishing mouse hemorrhagic shock resuscitation model

The invention discloses equipment for establishing a mouse hemorrhagic shock resuscitation model. The equipment comprises a surgery operation table, a body temperature maintaining device, a puncture module, an in-vitro blood heat preservation device, an artery puncture device, a blood transfusion / bloodletting device, a blood temporary storage device, an arterial blood pressure monitoring device and a three-way device. According to the invention, venipuncture catheterization is not needed in the blood transfusion / letting process, the purposes of blood transfusion / letting and real-time arterial blood pressure monitoring can be achieved only through arterial puncture catheterization, and the retention of veins can not only reduce the difficulty of the operation, but also ensure the backflow of tissue blood after the operation, so that the injury caused by the operation is reduced. According to the in-vitro blood heat preservation device, the in-vitro blood can be kept at a constant temperature, and the death risk of mice caused by body temperature changes can be effectively reduced. According to the blood transfusion / bloodletting device, the blood transfusion / bloodletting speed can be manually controlled, the problem that the blood transfusion / bloodletting speed cannot be controlled by manual bloodletting can be effectively solved, and heart failure caused by rapid and massive blood transfusion is avoided.
Owner:HEBEI PROVINCE CANGZHOU HOSPITAL OF INTEGRATED TRADITIONAL & WESTERN MEDICINE

Auxiliary device for sow catheter intubation

The utility model relates to the technical field of catheter placement devices, and discloses a sow catheter intubation auxiliary device which comprises an expansion column made of transparent materials, and an illuminating lamp is inserted in the middle of the expansion column; the inflation part is arranged on the surface of the expansion column and is made of a transparent material, and at least one catheter clamp is arranged on the surface of the inflation part; the moving part is located on the outer side of the inflation part and slidably connected with the expansion column, and a top inner cavity is higher than the top face of the clamp; the amplifying part is adjustably arranged at the top of the moving part corresponding to the urethral orifice of the sow. Through the cooperative arrangement of the expansion column, the illuminating lamp and the inflation piece, the whole body can be a luminous body in use, the illuminating effect is achieved, and the sow vaginal orifice inserting device is more convenient to insert into the sow vaginal orifice.
Owner:THE THIRD AFFILIATED HOSPITAL OF PLA NAVAL MEDICAL UNIVERSITY

An exhaust device and exhaust method for cattle stomach flatulence

The present invention belongs to the technical field of exhausting gas in cattle's stomach, specifically, an exhausting device for exhausting gas in cattle's stomach and an exhausting method thereof, comprising a placing device, a clamping device arranged at the bottom of the placing device, a bonding film clamped between the clamping devices, a mounting device detachably mounted on the top of the placing device, an exhausting device installed inside the mounting device, an acceleration device arranged in the middle of the exhausting device, and a buffer device arranged at the upper end of the exhausting device, wherein the acceleration device comprises a rotating wheel, which is rotatably connected in the middle of the exhausting device, and the outer wall of the rotating wheel is provided with rotating blades. The present invention can control the exhausting rate, so that the acceleration and deceleration of the exhausting can be freely controlled during the exhausting, thereby preventing the cattle from fainting or dying due to excessive exhausting.
Owner:承德市畜牧工作站

Laboratory mouse fixing mechanism and explosion experiment device

The invention discloses a laboratory mouse fixing mechanism and an explosion experiment device, and relates to the technical field of experiment auxiliary equipment. The conical barrel is of a hollow structure and is provided with a first end and a second end, the diameter of the first end is smaller than that of the second end, and the second end is detachably connected with one end of the barrel body; the fixing structure is arranged on the barrel and comprises a fixing plate and a guide assembly, the fixing plate is clamped in the barrel, the guide assembly comprises a sliding block and a sliding groove, the sliding groove is formed in the side wall of the barrel in a penetrating mode, the length direction of the sliding groove is consistent with the axial direction of the barrel, and the sliding block is clamped in the sliding groove and is in sliding connection with the sliding groove. One end of the sliding block is fixed to the fixing plate. The experimental mouse fixing device has the advantages that the body of an experimental mouse can be fixed through the fixing structure, the head of the experimental mouse can be fixed through the conical barrel, and the better fixing effect is achieved. Meanwhile, a structure for adjusting the angle of the fixing mechanism is arranged, so that the injury degree of explosion to the head of the laboratory mouse at different angles can be studied.
Owner:CHARACTERISTIC MEDICAL CENT OF THE CHINESE PEOPLES LIBERATION ARMY STRATEGIC SUPPORT FORCES

Knock injury simulation experiment device

The invention relates to the technical field of animal experiment instruments, in particular to a detonation injury simulation experiment device, which controls the displacement of a telescopic cylinder through a pressurizing mechanism, and controls the length of the telescopic cylinder through a telescopic mechanism, so that in the process that the pressurizing mechanism continuously pressurizes the inside of a sealed cavity, the detonation injury can be simulated. After the telescopic cylinder body sleeves the sealing mechanism to move for a specified distance, the telescopic cylinder body is separated from the sealing mechanism, and the sealing baffle plate is popped out, so that the gas with specified pressure is released, and the effect of controlling the gas flow with specified pressure to perform knocking impact simulation on animals is achieved. According to the experimental device, knocking impact simulation conditions in fixed spaces with different sizes are realized by arranging different pressurizing structures; meanwhile, structures such as a water tank and a pressure relief hole are arranged, so that the knocking impact condition when air or water is used as a medium can be simulated; in addition, by setting different rotation directions of the stainless steel mesh, the knocking impact conditions under different body positions and states can be simulated.
Owner:CHENGDU MILITARY GENERAL HOSPITAL OF PLA

Construction method and application of hypertrophy heart disease-pulmonary arterial hypertension model

The invention discloses a construction method and application of a hypercongenital heart disease-pulmonary arterial hypertension model, which better simulates children with the congenital heart disease in Yunnan by adopting the conditions of lateral anastomosis of aorta abdominalis and inferior vena cava and hypoxia feeding, and makes a new contribution to the research of pulmonary arterial hypertension. In the experimental shunt + hypoxia group and the monocrotaline + hypoxia group, the heart of the SD rat has the change of pulmonary arterial hypertension, four cases in the shunt + hypoxia group have tricuspid regurgitation, and the rest experimental rats have no tricuspid regurgitation.
Owner:KUNMING MEDICAL UNIVERSITY

Automatic spinal cord injury animal model preparation equipment

The invention provides automatic spinal cord injury animal model preparation equipment which comprises a bottom table, a first adjusting table is arranged at the upper end of the bottom table, a connecting frame is arranged in the first adjusting table in a limiting sliding mode, a second adjusting table is arranged at the upper end of the bottom table, a moving table is arranged in the second adjusting table in a limiting sliding mode, and a controller is arranged on the surface of the bottom table. A placing table is arranged at the upper end of the moving table, and extension tables are arranged at the two ends of the placing table. According to the animal experiment table, through the arrangement of the placement table, the expansion table, the movable clamping jaw and the automatic expansion adaptation assembly, the space in the placement table can be adjusted, so that the animal experiment table can adapt to experiments of animals with large sizes, and the clamping mechanism can be automatically adjusted when the animals with the large sizes are placed; according to the invention, the device can automatically adapt according to the body type of an animal, is suitable for experiments of various animal types, is not limited to a specific body type or species any more, and improves the flexibility of the experiments.
Owner:THE SEVENTH MEDICAL CENTER OF PLA GENERAL HOSPITAL

Adjustable nerve crush forceps with pressure sensing function

The utility model discloses a pair of adjustable nerve bruise forceps with pressure sensing function, which comprises a first forceps body, a second forceps body and a bruise clip, one end of the forceps body far away from a user is provided with a buckle, the buckle is connected with the bruise clip, and the first forceps body and the second forceps body drive the bruise clip to close after applying external force so as to bruise nerves. The bruise clamp is provided with various types of adaptive buckles, the bruise width of the nerve bruise clamp is adjusted to adapt to different experiment requirements and requirements of experiment objects, a pressure sensor is arranged at the position, close to the buckles, of the clamp body, the pressure sensor sends a sensing signal to a controller, an operator can control own force through a display screen of the sensor, and the operation is convenient. And the nerve injury degree is kept consistent. The dependence of the crushing degree on an operator is reduced, the operation fatigue is relieved, and a more accurate, scientific and efficient medical instrument is provided for animal experiment modeling of nerve crushing injuries.
Owner:HUNAN UNIV OF CHINESE MEDICINE

Method for constructing mouse ovarian endometriosis model

The invention relates to the technical field of biomedicine, and discloses a method for constructing a mouse ovary endometriosis model, which comprises the following steps: identifying endometrial tissues of a same donor mouse and bilateral ovaries of a receptor mouse; constructing an ectopic transplantation model of the receptor mouse, and monitoring the survival states of the receptor mouse in different postoperative stages in real time; the growth condition of the ectopic endometrial tissue on the ovary surface is analyzed, and the tissue structure and pathological change of the ectopic endometrial tissue are recognized; determining a lesion area of the ectopic transplantation model, analyzing pathological characteristics and a formation mechanism of the lesion area, and analyzing a correlation degree between the ectopic transplantation model and human endometriosis; and analyzing the simulation effect of the ectopic transplantation model on human endometriosis, and constructing the ovarian endometriosis model of the receptor mouse based on the modeling effect and the ectopic transplantation model. The model forming rate of the endometriosis model and the accuracy of the research result can be improved.
Owner:THE THIRD AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL UNIVERSITY (GUANGZHOU SEVERE MATERNAL TREATMENT CENTER GUANGZHOU ROUJI HOSPITAL)

Adjusting type spinal cord impact vibration injury device and injury method thereof

The invention discloses an adjustable spinal cord impact vibration injury device and an injury method thereof, and belongs to the technical field of spinal cord injury experiment research. Two lifting sliding rods are fixedly installed at the rear end of the base, and lifting sliding blocks capable of vertically sliding are installed on the lifting sliding rods. An angle adjusting mechanism is installed on the lifting sliding block, the movable end of the angle adjusting mechanism is detachably connected with a supporting tool used for fixing the experimental animal, and the angle adjusting mechanism is used for adjusting the angle of the supporting tool so that different parts of the experimental animal can face the base; the base is further provided with an impact triggering mechanism. Through the mode, the experimental animal spinal cord impact oscillation injury model prepared by adopting the technical scheme can well simulate the injury process of a clinical spinal cord injury patient and the pathophysiological change after injury; and the spinal cord impact vibration injury models with different injury modes and different injury degrees are prepared by changing the free falling body height of the experimental animal, the vertical impact rods made of different materials and the impact point location of the experimental animal.
Owner:SOUTHWEST JIAOTONG UNIV

Laboratory spinal cord injury three-dimensional electric striking device

The utility model provides a laboratory spinal cord injury three-dimensional electric striking device which is characterized in that longitudinal guide rails and a transverse guide rail are arranged on a bottom plate, two ends of the transverse guide rail are respectively connected with the longitudinal guide rails in a sliding manner, and a middle connecting seat is connected onto the transverse guide rail in a sliding manner; a vertical column is vertically arranged on the middle connecting seat, a large sleeve sleeves the vertical column in a sliding manner, a sliding driving block is arranged at the upper end of the large sleeve, a driving screw is sleeved with the sliding driving block in a threaded manner, the upper part of the driving screw is rotatably inserted into an adjustable connecting block, and the adjustable connecting block is fixedly mounted on the upper part of the vertical column; the large sleeve is provided with a scale section, and the scale section is slidably sleeved with a sliding connecting piece. An electromagnet is arranged on the sliding connecting piece; a small sleeve is arranged below the scale section, a striking rod is movably inserted into the small sleeve, and a magnetic attraction piece attracted by the electromagnet attraction head is arranged at the upper end of the striking rod. According to the device, the spinal cord of the rat can be accurately positioned and quantified in the modeling process, so that the same modeling condition is kept, and the modeling success rate and the modeling accuracy are improved.
Owner:AFFILIATED HOSPITAL OF YOUJIANG MEDICAL UNIV FOR NATTIES