592results about "Surgical veterinary" patented technology

The utility model discloses a rat thrombus forming device which comprises a blood collecting assembly and a thrombus forming assembly, the blood collecting assembly is used for collecting blood of a rat, and the blood collected by the blood collecting assembly is conveyed to the thrombus forming assembly to prepare thrombus; the blood sampling assembly comprises a bottom plate and a top plate, the top plate is located over the bottom plate, a vertical supporting rod is connected between the center of the bottom plate and the center of the top plate, the top plate can rotate around the supporting rod, a plurality of round holes are formed in the top plate in the annular direction, and blood collecting pipes are vertically placed in the round holes; a liquid outlet is formed in the bottom of the blood collecting pipe, a blood transfer pipe is connected to the liquid outlet, and the head end of the blood transfer pipe extends to the thrombus forming assembly; the thrombus forming assembly comprises a rectangular forming groove, a forming template made of rubber is fixed to the bottom of the forming groove, pits with honeycomb holes are densely distributed in the forming template, the diameter of each pit is 2-3 mm, and the depth of each pit is 2-3 mm.

The invention discloses a preparation method and system of a mouse craniocerebral thoracico-abdominal combined injury dynamic model based on AI, and belongs to the technical field of biomechanical injury. The method comprises the steps that impact is applied to a mouse skull, and the impact is conducted along an organ synergistic conduction chain so as to induce the craniocerebral thoracico-abdominal combined injury of the mouse; in the impact applying process, multi-modal physiological data are synchronously collected; and inputting the collected multi-modal physiological data into an AI analysis model, analyzing the injury mechanism of the craniocerebral thoracic-abdominal combined injury, and establishing a dynamic model based on an analysis result. According to the technical scheme provided by the invention, high-simulation modeling of multi-organ cascade injury is realized by constructing the organ synergistic conduction chain from the brain to the thoracic cavity; in combination with multi-modal physiological data synchronous acquisition and an AI analysis model, injury time sequence characteristics can be accurately extracted, a causal path of a local injury initiation system response is established, and the precision and practicability of compound injury mechanism prediction are improved.

The invention belongs to the technical field of medical instruments, and discloses a surgical instrument for building a traumatic brain injury mouse model.The surgical instrument comprises a tube blade, a limiter, a holding piece and a vacuum device, the tube blade is used for rotationally cutting into brain tissue of a mouse, the limiter is movably installed on the tube blade in the axial direction of the tube blade, and the vacuum device is arranged on the holding piece; the limiting device is used for abutting against the skull of the mouse, the holding piece is provided with an airflow channel, one end of the holding piece is connected with the pipe blade, one end of the airflow channel is communicated with the pipe blade, and the vacuum device is connected to the other end of the holding piece and connected with the other end of the airflow channel. According to the surgical instrument for building the traumatic brain injury mouse model, the problems that an injury area is uncontrollable and a focus area is difficult to quantify and unify in the current traumatic brain injury mouse model building process can be solved, so that the success rate and efficiency of model building are improved to the maximum extent.

The invention discloses a myocardial ischemia reperfusion injury animal model construction method and application thereof in the technical field of model animal preparation. The method comprises the steps of hypertension and hyperlipidemia pretreatment, standardized ischemia-reperfusion operation, immune microenvironment regulation and control and model evaluation and verification. According to the invention, model construction is carried out on an integrated model operation table, so that a standardized ischemia-reperfusion process is realized, reproducibility of a myocardial injury degree and an immune cell infiltration rule of the model is realized, and suitability of the model and nano-drug research is enhanced; and a reliable tool is provided for research and development of targeted drugs such as immune cell membrane coated nanoparticles.

The invention discloses an isolator for establishing a bone nonunion animal model and a preparation method of the isolator, and relates to the technical field of medical instruments, and the preparation method comprises the following steps: step 1, obtaining a hydrogen-containing silicone oil prepolymer with a side chain containing Si-H bonds; 2, obtaining a silica gel macromonomer with an epoxy group on a side chain; step 3, obtaining an anti-inflammatory functionalized silica gel macromonomer; 4, reconstructing the skeleton model in a three-dimensional manner, and creating a defect isolator model; 5, adding the anti-inflammatory functionalized silica gel macromonomer obtained in the step 3 and a reactive diluent into a mixing tank, adding a cross-linking agent and polyether modified polydimethylsiloxane under mechanical stirring, stirring for 30 minutes, defoaming for 2 hours under 500Pa vacuum, and standing and curing in a darkroom after defoaming; and 6, a multi-material-box DLP photocuring 3D printer is adopted for isolator printing. According to the method, observation interference on the bone nonunion pathological process is fundamentally reduced, and high-fidelity modeling construction is achieved.

The invention provides a method for establishing a mouse postoperative delirium model under a simulated high altitude urgent entry environment, and relates to the technical field of animal model establishment. According to the method for establishing the model for simulating postoperative delirium of the mouse in the sudden entering plateau environment, a control group (group C), a plateau group (group H), a POD model group (group P) and a plateau POD model group (group HP) are included, behavior changes of the mouse are evaluated through a Y maze experiment, then the mouse is killed, brain tissue is taken, and the mouse is subjected to postoperation delirium simulation in the sudden entering plateau environment. The mouse hippocampus tissue structure damage change is observed through morphological methods such as Nissl staining and a transmission electron microscope, meanwhile, blood is taken through mouse eye sockets, the concentration of inflammatory related indexes IL-6 and TNF-alpha in serum is measured through an ELISA method, and the stability and repeatability of model establishment are known. The plateau postoperative delirium mouse model prepared by the invention can generate obvious damage to brain tissues and neurological functions, and is high in operability and good in repeatability.

The utility model relates to the technical field of animal husbandry midwifery, in particular to a multifunctional midwifery auxiliary device and obstetric table integrated structure which comprises an obstetric table and an obstetric table, and a groove is formed in one side of the obstetric table; the adjusting mechanism is arranged at the bottom of the inner wall of the obstetric table, and the adjusting mechanism extends to the other side of the obstetric table; the supporting mechanism is arranged on the adjusting mechanism, and the adjusting mechanism is used for driving the supporting mechanism to move left and right; by arranging the fixing plate, the one-way threaded rod, the first rotating handle, the moving table, the limiting groove, the transverse rod, the second U-shaped ring and the fixing rod, the hip of a cow can be fixed, meanwhile, the weight bearing force generated when a midwifery holds the middle portion of the fixing rod by hands can be effectively reduced, time and labor are saved when the device is used, the overall labor burden is reduced, and the working efficiency is improved. The operation is convenient and simple, and integrated connection is realized, so that the efficiency of aiding cow delivery is improved.

The invention discloses a low-intensity transcranial focused ultrasound cerebral apoplexy rehabilitation animal experiment method and system. The method sequentially comprises the following steps of ultrasonic parameter safety calibration, animal screening and baseline establishment, cerebral apoplexy animal model preparation and establishment, ultrasonic intervention treatment, neurobehavioral dynamic evaluation, tissue sample acquisition and processing and multi-modal tissue inspection. The system comprises a stimulation unit, a positioning unit and a control unit, and is used for realizing accurate and parameter-controllable ultrasonic intervention. By constructing a complete research closed loop from parameter safety verification and standardized model intervention to multi-dimensional effect evaluation, the problems of blind parameter selection, single evaluation system and nonstandard experimental process in the prior art are solved, and a set of standardized and repeatable research normal form is provided. The rehabilitation effect of the LIFU on the cerebral apoplexy can be comprehensively and objectively evaluated, and parameter optimization can be guided.

The utility model discloses an eyeball holder. The eyeball holder comprises a clamping assembly, the clamping assembly comprises a first clamping arm and a second clamping arm which are arranged in a crossed mode. A first clamping part is arranged at one end of the first clamping arm; a second clamping part is arranged at one end of the second clamping arm; the first clamping part is detachably connected with the second clamping part; the first clamping part and the second clamping part are each of a hemispherical structure with a containing space inside. The side wall of the first clamping part and the side wall of the second clamping part are each provided with at least two through holes. The device has the beneficial effects that when the eyeball is taken, the contact area between the first clamping part and the in-vitro eyeball and the contact area between the second clamping part and the in-vitro eyeball are large, and damage to the in-vitro eyeball is avoided; and along with the continuous tightening of the clamping assembly, liquid between the in-vitro eyeball and the clamping instrument is gradually separated through the through hole, so that the solution for soaking the in-vitro eyeball is prevented from hindering the work of the clamping instrument, and the in-vitro eyeball is prevented from sliding off from the clamping instrument.

The present application relates to the field of model construction, in particular to a kind of construction method of vertebral artery compression rat model, the inner diameter and blood flow velocity of normal rat vertebral artery are obtained by ultrasonic detection;Anesthetize rat, skin preparation, disinfection, incision, expose vertebral artery;According to the required compression degree, select the tissue clip of corresponding specification, fix on vertebral artery, keep vertebral artery in compression state;Suture incision, disinfection, bandage;After rat awakens, daily care, feed, until incision healing;Ultrasonic detection is carried out, the inner diameter and blood flow velocity of the vertebral artery of rat model are obtained, compared with the inner diameter and blood flow velocity of the vertebral artery of the same age healthy rat or rat before modeling, whether it meets the standard of successful modeling is judged.

The sampling detection device comprises a clamp body, a handle, a movable tool apron, a sample collection container and a cutting tool bit, the cutting tool bit comprises a tool and a butt joint, the butt joint is fixed to the end of the tool, the end of the butt joint is provided with an annular medicine storage bin, and an opening of the annular medicine storage bin faces the tool; a medicine storage and release structure is arranged in the annular medicine storage bin, an extrusion part is further arranged on the butt joint in a sliding mode, and an elastic pre-tightening part is arranged between the extrusion part and the butt joint. According to the sampling detection device, through a single handle driving source and an ingenious mechanical structure design, multiple functional units of cutting, sampling, transferring and dosing are highly integrated, multi-functional synchronous cooperation under coherent mechanical actions is achieved, the livestock ears serve as mechanical transmission media, and a dosing mechanism is automatically triggered in the movement process after sampling. Therefore, the time, the position and the triggering condition of liquid medicine release and the sampling action form internal and inevitable mechanical linkage and closed-loop feedback.

To provide a corner angle protector capable of preventing foreign matter from flowing into a corner angle during intraocular surgery, and a method for manufacturing the same.SOLUTION: The corner angle protector 1 includes a C-shaped member 2 that is placed at a corner angle through an incision site of an eyeball and is deformable in accordance with a shape of the corner angle in a state where the C-shaped member 2 is placed at the corner angle, and a thread 3 that is connected to one of opposing end portions of the C-shaped member 2 and can be pulled by a user to pull out the C-shaped member 2 placed at the corner angle from the incision site. The end of the C-shaped member 2 to which the thread 3 is connected is formed into a conical shape with a rounded apex.SELECTED DRAWING: Figure 1

The invention provides a TTA bone plate. The TTA bone plate comprises a bone plate body and a plurality of connecting parts connected to the bone plate body. The bone plate body is provided with a first end and a second end which are oppositely arranged in the height extending direction of the bone plate body, and the multiple connecting parts are located on the two opposite sides of the first end in the first direction respectively. The bone plate body is provided with a cavity and two windows formed in the two opposite sides of the bone plate body in the first direction, and the two windows communicate with the cavity. At least two supporting beams which are connected in a crossed mode are arranged in each window, at least one end of each supporting beam is connected with the inner wall of the corresponding window, and the supporting beams are obliquely arranged relative to the height extending direction of the bone plate body. The TTA bone plate not only can bear load pressure in the first direction, the second direction and the third direction, but also can bear load pressure in the direction forming an included angle with the first direction, the second direction or the third direction, so that the TTA bone plate is better in mechanical property, and the treatment effect of the TTA bone plate is better.

The present invention relates to a device for locating (100) pituitary fossa in veterinary medicine and a method for locating the pituitary fossa in veterinary medicine by means of such a device.

The utility model provides an electrocardio automatic triggering type myocardial trauma impact device which comprises an impactor and a driver, and the driver is electrically connected with the impactor. The impactor comprises a front mounting seat, a rear mounting seat, two guide rails arranged in parallel, a magnet, a magnetizer, an impact structure and a buffer structure; the driver comprises an electrocardio wire hole, an access line hole, an output line hole and a force adjusting knob. The impactor adopts an electromagnetic driving principle, and can quickly push the impact module to generate impact force at the moment of electrification, so that the target is impacted. The driver is communicated with an external power supply, can store energy, and can rapidly discharge electricity to drive the impactor when percussion is needed; the energy adjusting module can adjust the magnitude of stored energy and change energy released during discharging, so that the impact strength is adjusted according to needs, and the clinical injury degree is achieved.

The utility model relates to the technical field of medical surgery, in particular to a combinable surgical blade which comprises a hollow knife handle, a fixing block, clamping pieces and a knife body, the fixing block is arranged in the hollow knife handle in a sleeved mode, the two sides of one end of the fixing block are connected with the clamping pieces through connecting rods, limiting holes are formed in the clamping pieces at equal intervals, and the knife body is connected with the hollow knife handle in a sleeved mode. A knife body main body is clamped between the clamping pieces, and limiting convex blocks are welded to the two sides of the knife body main body at equal intervals and located in the limiting holes; a blade is arranged at one end of the bottom of the knife body, and a knife point is arranged at the top end of the blade. The scalpel blade is convenient to assemble and disassemble quickly, the clamping stability of the scalpel body is good, the problem that a traditional scalpel blade is clamped in a limiting through groove in the middle of the scalpel body through a clamping plate and is prone to sliding is solved, subcutaneous elastic adhesion tissue can be sawed off through sawteeth at the top of the scalpel body, and the using effect is improved.

The present application relates to the technical field of medicine, and specifically includes the application of immunosuppressants in the preparation of drugs for treating pulmonary hypoperfusion type congenital heart disease, and further provides a premature infant pulmonary hypoperfusion animal model, and results show that lung development is significantly improved after using immunosuppressants. The present application verifies the Wnt pathway which is critical for lung development, indicates that immunosuppressants can improve the Wnt pathway changes caused by pulmonary hypoperfusion, confirms that immunosuppressants have a therapeutic effect on the pulmonary hypoperfusion type congenital heart disease caused by pulmonary hypoplasia, provides a new method and idea for improving lung development of such children, and thereby improves the long-term survival quality of congenital heart disease children in China.

A surgical guide adapted to receive and guide a surgical instrument for performing a bone osteotomy, the surgical guide including a body formed as an elongate block, the block further including first and second fixation apertures, the second fixation aperture adapted to receive a secondary fixation device on a second angle oblique to angle of the first fixation aperture, one or more further positioning apertures and a cutting channel.

A garment includes an outer shell, first and second electrode snaps located on an outer surface of the outer shell, first and second conductive rubber electrodes located inside the outer shell, a first conductive fabric strip connected to the first electrode snap and the first conductive rubber electrode, and a second conductive fabric strip connected to the second electrode snap and the second conductive rubber electrode.

The utility model discloses a mouse nose tissue sample sampling device, which relates to the technical field of biomedical research and comprises an operating table and a cutting mechanism. A nose tissue sample contour is arranged on the operation table; the cutting mechanism comprises a frame and at least one cutting assembly. The four corners of the operation table are each correspondingly provided with a stand column. The frame is located above the operation table and arranged on the stand columns in a sliding mode in the vertical direction. In a natural state, the frame can keep a distance away from the operation table; the cutting assembly is arranged on the frame in a sliding mode in the first direction, and the first direction is parallel to the top face of the operation table and perpendicular to the vertical direction. The lower end of the cutting assembly is provided with a cutting blade. An operator can accurately cut a mouse nose tissue sample, and the injury risk of the operator is reduced.

The utility model relates to the technical field of animal skin wound experiment instruments, in particular to a mouse back skin wound traction device which comprises a traction mechanism and a fixing mechanism. The fixing mechanism is installed at the bottom of the traction mechanism, the traction mechanism comprises two first fixing plates, first threaded holes are formed in one sides of the two first fixing plates, and first threaded rods are in threaded connection with the inner side walls of the two first threaded holes; the adjacent ends of the two first threaded rods are fixedly connected with a connecting block. In the using process of the mouse fixing device, the using number of the fixing blocks is adjusted according to the size of a mouse, the using number of the fixing blocks is increased, so that the fixing requirements of different mice are met, the angle of the fixing blocks can be adjusted, and the mouse fixing device is convenient to use and high in practicability. The fixing block is more attached to the skin of the mouse, the fixing effect is improved, and therefore the back skin wound surface of the mouse can be pulled conveniently.

The invention relates to a flexible conductive intravenous stent based on functional electrical stimulation. The invention belongs to the fields of biomedical engineering and the like. The PCL-Gr extravascular stent is prepared by utilizing an electrostatic spinning technology, and the PCL-Gr extravascular stent wraps the periphery of the transplanted vein to provide necessary mechanical support for the transplanted vein so as to maintain the structural stability of the transplanted vein, so that the risk of restenosis caused by hemodynamic change is reduced. And meanwhile, functional electrical stimulation is accurately applied to transplanted veins by utilizing conductivity, so that double mechanisms of promoting endothelialization and inhibiting smooth muscle cell proliferation are achieved, and the risk of intimal hyperplasia is effectively reduced.

The livestock dehairing device comprises a concave table, an L-shaped frame is fixed to the left side of the concave table, a sliding groove and a U-shaped rod are formed in the top face of the L-shaped frame, the U-shaped rod is fixed to the right side of the top face of the L-shaped frame, and the bottom of the outer wall of the U-shaped rod is fixedly connected with the front face and the back face of the concave table; the concentric-square-shaped frame is fixed to the top face of the L-shaped frame, sliding grooves are formed in the top face and the bottom face of the concentric-square-shaped frame, a threaded rod penetrates through the left side and the right side of the inner wall of the concentric-square-shaped frame and is rotationally installed on the left side and the right side of the inner wall of the concentric-square-shaped frame, two inner threaded rods are installed on the inner wall of a threaded groove of the threaded rod in a meshed mode, and the outer walls of the inner threaded rods make sliding contact with the interiors of the sliding grooves of the concentric-square-shaped frame. According to the livestock breeding animal fixing device, the two sides of a livestock breeding animal are limited through the arc-shaped plates, and therefore the problem that the animal is accidentally injured by a shaver due to the fact that the livestock breeding animal moves disorderly is avoided.

The invention relates to the field of biological robots and neural engineering, and discloses an electrical stimulation control protection device for a turtle robot, which comprises a neck biocompatibility limiter, the neck biocompatibility limiter is of a sleeve structure and is composed of a rigid clamping part and a flexible limiting disc, the neck of the turtle robot penetrates through the rigid clamping part and the flexible limiting disc, and the flexible limiting disc is connected with the neck of the turtle robot. The flexible limiting disc abuts against the tortoise shell of the tortoise robot, the rigid clamping part abuts against the skull of the tortoise robot, the rigid clamping part limits head retraction of the tortoise robot, and the flexible limiting disc is used for ensuring the freedom degree of the tortoise robot in other directions. The mechanical protection, sealing performance and diversion performance of the waterproof sealing electrical stimulation sleeve module ensure the position stability of the electrode under long-term violent activity and water flow impact.

The application provides a construction system and device of a non-human animal model of tension pneumothorax, and the system comprises: a fixing unit for fixing the non-human animal; a first processing unit for puncturing a puncture needle to the parietal pleura, making a guide wire pass through the needle cavity of the puncture needle to enter the pleural cavity, and withdrawing the puncture needle; a second processing unit for inserting a catheter along the guide wire to make the catheter enter the pleural cavity, pulling out the guide wire, and fixing the catheter; a third processing unit for unidirectional air injection into the pleural cavity through the catheter; and a fourth processing unit for monitoring the range of pneumothorax, determining that the non-human animal model of tension pneumothorax is obtained when the lung sliding of the injection side chest is greater than or equal to 4 / 6 area and lung points are observed, stopping air injection, and obtaining the non-human animal model of tension pneumothorax. The construction success rate of the application is 100%, the construction process is rapid, repeatable and objective in determination, and the application can provide a rapid and repeatable platform for diagnostic research, decompression technology evaluation and training.

The invention belongs to the technical field of artificial insemination of bumblebees, and particularly relates to a male bumblebee sperm collecting device. The male bee seminal vesicle extraction platform is arranged on the base, the male bee seminal vesicle extraction platform is used for clamping the male bee seminal vesicle glass sheet, the male bee seminal vesicle glass sheet is used for placing a male bee seminal vesicle, and the male bee seminal vesicle extraction platform drives the male bee seminal vesicle glass sheet to move in the horizontal direction of the base; the insemination needle fixator is vertically arranged on the base in a lifting mode and used for fixing a glass needle, and the glass needle faces the male bee seminal vesicle glass sheet. Through the device, the extraction efficiency can be remarkably improved, so that the sperm exposure time is effectively shortened, and relatively high vitality is kept.

The invention discloses a method for constructing a lumbar spinal stenosis animal model, which comprises the following steps of: fixing an experimental rabbit at a prone position, and then forming a 2-3cm incision in the back side of the waist along the longitudinal direction so as to completely expose an intervertebral plate window between a first lumbar vertebra and a second lumbar vertebra; a disposable venous indwelling needle is used for puncturing the ligamentum flavum at the interlaminal window and then puncturing the disposable venous indwelling needle into the spinal canal, and then a metal needle core of the venous indwelling needle is pulled out, so that the soft catheter part of the venous indwelling needle is indwelled in the spinal canal; uniformly mixing PMMA bone cement powder and liquid to prepare fluid bone cement, extracting the bone cement by using an injector, slowly injecting the bone cement into the spinal canal, and removing the soft catheter after injection is completed; the injected bone cement is adhered to the inner wall of the spinal canal after being solidified, so that the inner diameter and the volume of the spinal canal are reduced in physical space, compression on spinal nerves is formed, and the animal model with lumbar spinal stenosis is obtained. The problem that in the preparation process of an animal model, nerves are prone to being damaged, and research test requirements cannot be met is solved.

The application provides a laboratory mouse tail skinner and an operating method thereof, which comprises a base, a cutting mechanism comprising a first assembly ring and a plurality of cutting assemblies, any cutting assembly comprising a first mounting seat and a cutting knife, the cutting knife being arranged on the first mounting seat and extending towards the center of the first assembly ring, and a skinning mechanism comprising a second assembly ring and a plurality of skinning assemblies, the second assembly ring being arranged concentrically with the first assembly ring, and the skinning assembly comprising a second mounting seat and a skinning knife, the skinning knife being connected to the second mounting seat and facing along the axial direction of the second assembly ring. The application replaces manual operation of a handheld blade with a mechanical structure, effectively avoiding the safety hazard of a sharp blade scratching the fingers of a laboratory worker. In addition, the application has a simple body structure and is convenient to assemble, can flexibly adjust the positions of the cutting assemblies and the skinning assemblies according to laboratory mouse tails of different specifications, has a wide range of applications, and has high practicality and promotional value.

The invention discloses an intelligent positioning type cow dystocia midwifery instrument and an operation method. The intelligent positioning type cow dystocia midwifery instrument comprises an intelligent positioning module, a midwifery execution module, a main control module and a man-machine interaction unit. The intelligent positioning module is used for acquiring the spatial position and posture data of a fetus in a birth canal of a cow, and comprises a stretching type ultrasonic positioning unit and a visual positioning unit; the midwifery execution module comprises an adjustable clamping mechanism and a traction driving mechanism and is used for implementing stable clamping and directional traction on a fetus; the instrument is more convenient to disassemble, clean and maintain due to the modular design, the 10.1-inch high-definition man-machine interaction touch screen integrates the functions of image display, parameter setting, early warning prompt and the like, the interface is visual, the training cost of operators is reduced, the sanitation and safety of operation are ensured through the double disinfection and sterility detection process, and secondary infection is prevented.

To provide a livestock birthing support device that can reduce the physical burden on caregivers assisting in the birthing of livestock. [Solution] The livestock birthing support device comprises a support body 10 having a lower body support section 11 for supporting the lower body of the caregiver and an upper body attachment section 12 for being attached to the upper body of the caregiver, and a powered traction means 20 attached to the support body 10 and wound with a pulling wire. The tip of the pulling wire extended forward from the powered traction means 20 is attached to the fetus inside the livestock mother's body, and the fetus can be removed from the mother's body by winding up the pulling wire.