26276 results about "Closed loop" patented technology

One or more implantable system control units (SCU) apply one or more stimulating drugs and/or electrical pulses to one or more predetermined areas affecting circulatory perfusion. The SCU preferably includes a programmable memory for storing data and/or control parameters, and preferably uses a power source/storage device, such as a rechargeable battery. If necessary, periodic recharging of such a power source/storage device is accomplished, for example, by inductive coupling with an external appliance. The SCU provides a means of stimulating a nerve(s) or other tissue with electrical and/or infusion pulses when desired, without the need for external appliances during the stimulation session. When necessary, external appliances are used for the transmission of data to and/or from the SCU(s) and/or for the transmission of power. In a preferred embodiment, the system is capable of open- and closed-loop operation. In closed-loop operation, at least one SCU includes a sensor, and the sensed condition is used to adjust electrical and/or drug stimulation parameters.

The present invention relates generally to a tissue closure device and in particular to a tissue closure device having a plurality of configurations providing for delivery and use in minimally invasive procedures. A tissue closure device (100) is provided from shape memory or super-elastic materials for closing a tissue site opening (50), the device comprising a plurality of tissue anchors (130) extending from a closed loop surface (110) wherein the plane of said tissue anchors is provided at an angle essentially perpendicular with respect to the plane of said closed loop surface; a. wherein said plurality of tissue anchors (130) comprise a proximal end (130p) and a distal end (130d); said distal end provided for anchoring said device onto tissue (50); and wherein said proximal end (130p) is fluid with and extends from said closed loop surface (110); and b. said closed loop surface (110) having a plurality of configurations including: a delivery configuration (1OOd), an open configuration (1000) and a closed configuration (100c) wherein said closed loop surface (110) may undergo a transformation between one of said plurality of configurations to another; said delivery configuration (1OOd) defining a low profile of said device (100) and adapted for delivery to a tissue site (50) through a small profile access point having a first diameter and wherein said closure device is utilized to close a tissue site having a second diameter such that said second diameter is larger than said first diameter.

A surgical instrument for being endoscopically or laparoscopically inserted into a surgical site for simultaneous stapling and severing of tissue includes load sensing pressure transducers strategically placed for closed loop control and monitoring. Load sensing within a staple applying assembly (end effector) may provide feedback for preventing firing with insufficient or too much tissue, or to sense appropriate presence buttress material, to deploy buttress material after firing is sensed.

The invention relates to a microfabricated device for the rapid detection of DNA, proteins or other molecules associated with a particular disease. The devices and methods of the invention can be used for the simultaneous diagnosis of multiple diseases by detecting molecules (e.g. amounts of molecules), such as polynucleotides (e.g., DNA) or proteins (e.g., antibodies), by measuring the signal of a detectable reporter associated with hybridized polynucleotides or antigen/antibody complex. In the microfabricated device according to the invention, detection of the presence of molecules (i.e., polynucleotides, proteins, or antigen/antibody complexes) are correlated to a hybridization signal from an optically-detectable (e.g. fluorescent) reporter associated with the bound molecules. These hybridization signals can be detected by any suitable means, for example optical, and can be stored for example in a computer as a representation of the presence of a particular gene. Hybridization probes can be immobilized on a substrate that forms part of or is exposed to a channel or channels of the device that form a closed loop, for circulation of sample to actively contact complementary probes. Universal chips according to the invention can be fabricated not only with DNA but also with other molecules such as RNA, proteins, peptide nucleic acid (PNA) and polyamide molecules.

Systems and methods are provided for sensing analyte (e.g., glucose) and/or dispensing therapeutic fluid (e.g., insulin). The systems and methods are based on transporting the therapeutic fluid through a cannula at least a portion of which is permeable to molecule of the analyte. Sensing and detection of the concentration level of the analyte can be carried out by optical sensing, electrochemical sensing, acoustical sensing etc. Sensing and dispensing can be carried out by sensing and dispensing device operating in either closed or semi-closed loop.

An electrosurgical system is disclosed comprising a generator configured to electrosurgical coagulation waveforms. The generator includes a closed loop control system for controlling the electrosurgical coagulation waveforms. The closed loop control system includes a sensor configured to sense a tissue property and/or an energy property and to transmit the tissue property and/or the energy property as one or more sensor signals having an amplitude. The control system also includes a gain controller configured to process the at least one sensor signal to reduce the amplitude of the sensor signals and to obtain a signal to noise ratio of the at sensor signals within a predetermine range. A microprocessor coupled to the generator and is configured to adjust the electrosurgical coagulation waveforms as a function of the sensor signals.

A closed loop infusion system controls the rate that fluid is infused into the body of a user. The closed loop infusion system includes a sensor system, a controller, and a delivery system. The sensor system includes a sensor for monitoring a condition of the user. The sensor produces a sensor signal, which is representative of the condition of the user. The sensor signal is used to generate a controller input. The controller uses the controller input to generate commands to operate the delivery system. The delivery system infuses a liquid into the user at a rate dictated by the commands from the controller. Preferably, the sensor system monitors the glucose concentration in the body of the user, and the liquid infused by the delivery system into the body of the user includes insulin.

A method and apparatus to provide therapy to a patient for protecting cardiac tissue from insult is disclosed. The method comprises delivering electrical stimulation to one or more predetermined portions of the nervous system in a patient's body; and monitoring one or more physiologic indices of the body to determine whether the delivered therapy is effective. That is, a closed-loop feedback controller is used to apply electrical stimulation to preselected regions of the patient's body, and then the physiologic response of the patient is monitored to determine the efficacy of the stimulation.

Controls for an optical scanner, such as a single fiber scanning endoscope (SFSE) that includes a resonating optical fiber and a single photodetector to produce large field of view, high-resolution images. A nonlinear control scheme with feedback linearization is employed in one type of control to accurately produce a desired scan. Open loop and closed loops controllers are applied to the nonlinear optical scanner of the SFSE. A closed loop control (no model) uses either phase locked loop and PID controllers, or a dual-phase lock-in amplifier and two PIDs for each axis controlled. Other forms of the control that employ a model use a frequency space tracking control, an error space tracking control, feedback linearizing controls, an adaptive control, and a sliding mode control.

A neurological control system for modulating activity of any component or structure comprising the entirety or portion of the nervous system, or any structure interfaced thereto, generally referred to herein as a “nervous system component.” The neurological control system generates neural modulation signals delivered to a nervous system component through one or more intracranial (IC) stimulating electrodes in accordance with treatment parameters. Such treatment parameters may be derived from a neural response to previously delivered neural modulation signals sensed by one or more sensors, each configured to sense a particular characteristic indicative of a neurological or psychiatric condition.

A method and apparatus are provided for monitoring and controlling substrate processing parameters for a cluster tool that utilizes chemical vapor deposition and/or hydride vapor phase epitaxial (HVPE) deposition. In one embodiment, a metal organic chemical vapor deposition (MOCVD) process is used to deposit a Group III-nitride film on a plurality of substrates within a processing chamber. A closed-loop control system performs in-situ monitoring of the Group III-nitride film growth rate and adjusts film growth parameters as required to maintain a target growth rate. In another embodiment, a closed-loop control system performs in-situ monitoring of film growth parameters for multiple processing chambers for one or more film deposition systems.

An ablation catheter comprises a catheter body extending longitudinally between a proximal end and a distal end along a longitudinal axis; and an ablation element assembly comprising ablation elements connected to the catheter body, each ablation element to be energized to produce an ablation zone. The ablation elements are distributed in a staggered configuration such that the ablation zones of the ablation elements span one or more open arc segments around the longitudinal axis, but the ablation zones of all ablation elements projected longitudinally onto any lateral plane which is perpendicular to the longitudinal axis span a substantially closed loop around the longitudinal axis. Since the ablation zones do not form a closed loop, the risk of renal artery/vein stenosis is reduced or eliminated. Since the ablation zones of all ablation elements projected longitudinally onto any lateral plane span a substantially closed loop, substantially complete renal denervation is achieved.

The invention discloses a dynamic target tracking and positioning method of an unmanned plane based on vision, and belongs to the navigation field of the unmanned planes. The dynamic target tracking and positioning method comprises the following steps of: carrying out video processing, dynamic target detecting and image tracking; carrying out cloud deck servo control; establishing a corresponding relationship between a target in the image and a target in the real environment, and further measuring the distance between a camera and a dynamic target to complete precise positioning of the dynamic target; and enabling an unmanned plane control system to fly by automatically tracking the dynamic target on the ground. The dynamic target tracking and positioning method of the unmanned plane based on the vision can automatically realize the movement target detecting, image tracking and optical axis automatic deflecting without the full participation of the people, so that the dynamic target is always displayed at the center of an image-forming plane; and the distance between the unmanned plane and the dynamic target is measured in real time according to an established model on the basis of obtaining the height information of the unmanned plane. Therefore, the positioning of the dynamic target is realized; closed-loop control is formed by using the positioned dynamic target as a feedback signal, so that the tracking flight of the unmanned plane is guided.