3895results about "External electrodes" patented technology

The invention provides a tumor electric field treatment system, an electrode slice temperature detection method and an electrode slice anomaly detection method, the system comprises an electrode slice and an adapter provided with a first controller, the electrode slice comprises a plurality of electrode units and a plurality of temperature detection units, the plurality of temperature detection units are divided into a plurality of row groups and a plurality of column groups, and the first controller is connected with the adapter. The grounding ends of the temperature detection units in each row group are jointly connected to the same grounding wire, and the signal ends of the temperature detection units in each column group are connected to the same dual-purpose signal wire after being in short circuit with the corresponding electrode units; when the dual-purpose signal line is connected to the temperature sampling point, the grounding wires are sequentially conducted, so that temperature detection signals detected by the temperature detection units are sampled based on the temperature sampling point; when the dual-purpose signal line is connected to the alternating power line, alternating electric signals are transmitted to the electrode units. Therefore, the temperature of the electrode plate can be detected by using fewer conductive traces, and whether the electrode plate is abnormal or not can be judged through temperature detection.

The invention belongs to the technical field of medical instruments, and particularly relates to a spinal epidural ventral side double-wing-shaped stimulation electrode and motion function reconstruction system, the spinal epidural ventral side double-wing-shaped stimulation electrode and motion function reconstruction system comprises two wing panels, each wing panel comprises a flexible substrate, the flexible substrate is provided with two bifurcated preset-curvature double-wing structures; the electrode contact array is integrated on the flexible polar plate through a bonding pad; according to the double-wing-shaped flexible substrate, through a double-wing structure with a preset curvature, after being unfolded under the driving of a nickel-titanium alloy framework, the double-wing-shaped flexible substrate accurately covers a spinal cord ventral side and double-side anterior angle motor neuron pool, and the problem that a traditional single-piece / rod-shaped electrode can only cover a back side sensing area and cannot cover a back side sensing area is solved. The ventral motor neuron group cannot be directly activated; a stimulation target spot is transferred to a ventral functional core area from a dorsal non-target area for the first time, and the anatomical suitability bottleneck of motor function reconstruction is solved.

The invention provides a tumor electric field treatment system, an electrode slice temperature detection method and an electrode slice anomaly detection method, the system comprises an alternating current signal generator, an electrode slice and a controller, the electrode slice comprises a plurality of electrode units and a plurality of temperature detection units, the plurality of temperature detection units are divided into a plurality of row groups and a plurality of column groups, and the plurality of electrode units are connected with the controller. The grounding ends of the temperature detection units in each row group are jointly connected to the same grounding wire, and the signal ends of the temperature detection units in each column group are connected to the same dual-purpose signal wire after being in short circuit with the corresponding electrode units; when the dual-purpose signal line is connected to the temperature sampling point, the grounding wires are sequentially conducted, so that temperature detection signals detected by the temperature detection units are sampled based on the temperature sampling point; when the dual-purpose signal line is connected to the alternating power line, alternating electric signals are transmitted to the electrode units. Therefore, the temperature of the electrode plate can be detected by using fewer conductive traces, and whether the electrode plate is abnormal or not can be judged through temperature detection.

The invention provides a tumor electric field treatment system, an electrode slice temperature detection method and an electrode slice anomaly detection method, the system comprises an electrode slice and an adapter provided with a first controller, the electrode slice comprises a plurality of electrode units and a plurality of temperature detection units, the plurality of temperature detection units are divided into a plurality of row groups and a plurality of column groups, and the first controller is connected with the adapter. The grounding ends of the temperature detection units in each row group are jointly connected to the same grounding wire, and the signal ends of the temperature detection units in each column group are connected to the same dual-purpose signal wire after being in short circuit with the corresponding electrode units; when the dual-purpose signal line is connected to the temperature sampling point, the grounding wires are sequentially conducted, so that temperature detection signals detected by the temperature detection units are sampled based on the temperature sampling point; when the dual-purpose signal line is connected to the alternating power line, alternating electric signals are transmitted to the electrode units. Therefore, the temperature of the electrode plate can be detected by using fewer conductive traces, and whether the electrode plate is abnormal or not can be judged through temperature detection.

High-frequency irreversible electroporation (H-FIRE) is a tissue ablation modality employing bursts of electrical pulses in a positive phase-interphase delay-negative phase-interpulse delay pattern. Despite accumulating evidence suggesting the significance of these delays, their effects on therapeutic outcomes from clinically-relevant H-FIRE waveforms have not been studied extensively. The present invention provides methods of pulse delivery, including delays, that mitigate bubble formation and / or minimize the risk of arcing, such as due to the presence of bubbles, and / or minimize muscle stimulation are described herein.

The invention provides an adapter and a tumor electric field treatment system, an electrode plate comprises a plurality of electrode units and a plurality of temperature detection units, the plurality of temperature detection units are divided into a plurality of row groups and a plurality of column groups, and the grounding ends of the temperature detection units in each row group are connected to the same grounding wire. The signal end of each temperature detection unit in each column group is in short circuit with the corresponding electrode unit and then is connected to the same dual-purpose signal line; a bidirectional change-over switch of the adapter is configured to switch a dual-purpose signal line to be connected to a temperature sampling point or an alternating power line, and when the dual-purpose signal line is connected to the temperature sampling point, each grounding line is conducted in sequence so that a temperature detection signal detected by each temperature detection unit is sampled based on the temperature sampling point; and when the dual-purpose signal line is communicated with the alternating power line, an alternating current signal is transmitted to each electrode unit through the dual-purpose signal line, so that partition control and comprehensive temperature detection of the electrode plate are realized.

The invention provides a tumor electric field treatment system and an electrode slice temperature detection method, the system comprises an electrode slice and a controller, the electrode slice comprises a plurality of electrode units and a plurality of temperature detection units, the plurality of temperature detection units are divided into a plurality of row groups and a plurality of column groups, the grounding ends of the temperature detection units in each row group are jointly connected to the same grounding wire, and the signal ends of the temperature detection units in each column group are connected to the same dual-purpose signal wire after being in short circuit with the corresponding electrode units; when the dual-purpose signal line is connected to the temperature sampling point, the grounding wires are sequentially conducted, so that temperature detection signals detected by the temperature detection units are sampled based on the temperature sampling point; when the dual-purpose signal line is connected to the alternating power line, alternating electric signals are transmitted to the electrode units. In this way, a plurality of electrode units can be zoned and controlled using fewer conductive traces.

The invention discloses a patient improvement effect analysis method for controlling spinal cord electrical stimulation through an implantable brain-computer interface, and relates to the technical field of medical rehabilitation, and the method comprises the steps: multi-dimensional collaborative data collection: implanting electrodes in a target brain region and below a spinal cord injury segment, installing a detection element at an exoskeleton key part, and carrying out multi-dimensional collaborative data collection; a sensor is attached to a lower limb preset muscle group, electroencephalogram signals, SCS stimulation parameters, EXS motion data and neuromuscular response data are synchronously collected, and time correlation marks are embedded; according to the method, the reliability of motion intention decoding is remarkably improved by adopting a mode of combining multi-source signal preprocessing and a multi-mode intention recognition model, and in the signal preprocessing stage, the self-adaptive filtering algorithm combining Kalman filtering and wavelet threshold denoising is applied, so that the motion intention decoding efficiency is improved. SCS electrical stimulation interference, EXS motor noise and physiological noise in the electroencephalogram signals are effectively removed.

The invention relates to a three-dimensional spiral high-density neural electrode and a preparation method and application thereof. The three-dimensional spiral high-density neural electrode comprises a probe structure and a plurality of electrode sites. The probe structure is formed by curling a planar flexible electrode precursor, and at least one end of the probe structure is provided with a spiral outer surface of a three-dimensional spiral line structure. Electrode sites are distributed along a spiral path, have a size of 5-1000 [mu] m, and are used for contacting biological tissues. On the planar flexible electrode precursor, electrode sites are arranged on one or more straight lines forming an inclined angle alpha with the axial direction of the probe, and the spatial distribution is matched with the edge. Compared with the prior art, the method has the advantages that the constraint of a traditional wiring mode is broken through, the integration of high-density three-dimensional channels is realized under a micro size, and a new generation of solution is provided for a high-precision brain-computer interface, deep brain stimulation and a three-dimensional electroencephalogram.

Provided herein are methods of treating a patient comprising providing a medical apparatus comprising an external system and an implantable system, implanting the implantable system, and delivering at least one of power or data to the implantable system with the external system. The external system comprises: at least one external antenna configured to transmit a first transmission signal to the implantable system; an external transmitter configured to drive the at least one external antenna; an external power supply; and an external controller. The implantable system comprises: at least one implantable antenna configured to receive the first transmission signal from the first external device; an implantable receiver; at least one implantable functional element configured to interface with the patient; an implantable controller; an implantable energy storage assembly; and an implantable housing surrounding at least the implantable controller and the implantable receiver. Medical apparatus are also provided.

The invention provides an electrode plate and a tumor electric field treatment system, the electrode plate comprises a plurality of electrode units and a plurality of temperature detection units, the plurality of temperature detection units are divided into a plurality of row groups and a plurality of column groups, and the grounding ends of the temperature detection units in each row group are connected to a grounding pin through a control switch. The signal end of each temperature detection unit in each column group is connected to a bidirectional change-over switch through a dual-purpose signal line after being respectively in short circuit with the corresponding electrode unit; when the dual-purpose signal lines are connected to the temperature sampling points, temperature detection signals detected by the corresponding temperature detection units in the corresponding column groups are respectively sampled based on the temperature sampling points by configuring the on-off states of the control switches; when the dual-purpose signal lines are connected to the alternating power lines, alternating electric signals are applied to the electrode units in the corresponding column groups based on the alternating power lines. In this way, a plurality of electrode units can be zoned and controlled using fewer conductive traces.

The invention provides a brain organism closed-loop rehabilitation system and a control method thereof, belongs to the field of brain-computer interfaces and rehabilitation medical treatment, and is used for solving the problems of insufficient brain state perception, poor adaptability and low robustness of a brain organism rehabilitation system in related technologies. The method comprises the following steps: synchronously acquiring multi-modal physiological signals by cooperating with physiological signal monitoring, task induction and regulation and control equipment modules, removing artifacts through preprocessing and redundancy check, extracting neuroplasticity characteristics, dynamically adjusting weight decoding brain activity intentions, regulating and controlling stimulation parameters in a closed loop, and training an optimization model in combination with a multi-center federation; accurate and highly-adaptive rehabilitation regulation and control are realized, and the rehabilitation effect and the model generalization are improved.

Adjustable auricular nerve stimulation devices, and associated systems and methods, are disclosed herein. A representative device for delivering an electrical signal to a subject includes a signal delivery element including at least two electrodes configured to deliver the electrical signal to a first portion of the subject's ear. The device also includes a retention element configured to engage a second portion of the subject's ear. The device further includes an adjustment mechanism permitting movement of the signal delivery element relative to the retention element to place the at least two electrodes in contact with the first portion of the subject's ear.

The embodiment of the invention relates to the field of intelligent wearable equipment, in particular to intelligent ear vagus nerve regulation and control glasses and a control method, control device and regulation and control system thereof, and the method comprises the following steps: acquiring pupil dynamic characteristic parameters monitored by the intelligent ear vagus nerve regulation and control glasses; calling a trained machine learning model to analyze real-time physiological state information according to the pupil dynamic characteristic parameters; according to the real-time physiological state information obtained through analysis, generating an electrical stimulation control instruction corresponding to the real-time physiological state information; and controlling an ear vagus electrode in the intelligent ear vagus nerve regulation and control glasses to implement nerve regulation based on the electrical stimulation control instruction. According to the method, the limitation of fixed parameter output of a traditional ear vagus nerve stimulation device can be broken through, the individualization and accuracy of an ear vagus nerve stimulation scheme are improved, and the problem that the treatment effect is insufficient or discomfort is caused is solved.

The invention discloses a mouse spinal cord flexible electrode and a stimulation parameter optimization method, and relates to the technical field of parameter optimization. The mouse spinal cord flexible electrode comprises a soluble insertion layer, a gradient substrate layer, spinal cord anastomosis ribs, a conductive snakelike net, a hemispherical touch dot matrix, a microfluidic layer, an optical waveguide layer and a top packaging layer; the soluble insertion layer is photo-crosslinked PEG-DMA with the thickness of 5-25 m, the Young modulus is kept within the range of 0.8-1.5 GPa before implantation, and the soluble insertion layer is hydrolyzed in cerebrospinal fluid within 0.5-3 hours after implantation and completely falls off; the spinal cord anastomosis rib comprises an expandable S-shaped folding structure arranged on the upper surface of the gradient substrate layer, the distance between every two adjacent ribs ranges from 80 m to 200 m, the height of the folded state is not larger than 15 m, the height of the unfolded state ranges from 15 m to 40 m, and the spinal cord anastomosis rib is used for forming a cerebro-spinalfluid bypass groove extending in the longitudinal direction of the spinal cord on the surface of the dura mater. According to the invention, the positioning precision, safety and long-term efficiency of mouse spinal cord electrical stimulation can be effectively improved.

The invention provides a brain deep electrical stimulation electrode parameter determination method and related equipment, and the method comprises the steps: building a head simulation model which comprises conductivity distribution; determining one or more target stimulation target spots and one or more non-target inhibition areas on the head simulation model; based on one or more target stimulation target spots and one or more non-target inhibition areas, multiple groups of electrode configuration schemes are determined through an electrode positioning method, each group of electrode configuration scheme is configured on the head simulation model, and multiple groups of stimulation simulation models are obtained; performing finite element solution based on the anatomical structure and the conductivity distribution of each group of stimulation simulation models, and optimizing the electric field intensity of one or more target stimulation target spots and the electric field intensity of one or more non-target suppression regions to obtain a plurality of electrode parameters; and determining a target electrode parameter in the plurality of electrode parameters, and taking an electrode configuration scheme corresponding to the target electrode parameter as a target electrode configuration scheme.

The invention is applicable to the technical field of medical instruments, and provides a subskull epidural micro-invasive flexible brain-computer interface electrode, which comprises a plurality of electrode branches, each electrode branch comprises a linear flexible main body, and the flexible main body comprises a micro power supply circuit and a signal circuit which are solidified. A plurality of electrode units are arranged on the micro power supply circuit and the signal circuit at intervals, and the electrode units are electrically connected with the micro power supply circuit and the signal circuit. The brain-computer interface electrode is in a flexible line type, can be implanted into the middle artery of the meninx, does not need craniotomy, is a micro-invasive brain-computer interface, has data monitoring accuracy close to that of an invasive brain-computer interface, does not need to worry about inflammatory response, immunostimulation, biocompatibility, brain tissue damage and other adverse factors after long-term implantation, and is suitable for popularization and application. And the thrombogenic risk of a vein stent brain-computer interface does not exist.

The invention provides a tumor electric field treatment system and an electrode slice quality detection method, the system comprises electrode slices, each electrode slice comprises a plurality of electrode units and a plurality of temperature detection units, the plurality of electrode units are divided into a plurality of row groups and a plurality of column groups, the grounding ends of the temperature detection units in each row group are short-circuited to the same grounding wire, and the grounding ends of the temperature detection units in each column group are short-circuited to the same grounding wire; the signal end of each temperature detection unit in each column group is in short circuit with the corresponding electrode unit and then is jointly connected to the same dual-purpose signal line. Thus, the electric field generator or the adapter can use fewer conductive traces to perform partition control on a plurality of electrode units and sampling of temperature detection signals, and can perform quality detection on the electrode slices based on the sampled temperature detection signals.

The invention discloses a pelvic floor muscle repairing instrument, a pelvic floor muscle training indication method, pelvic floor muscle training indication equipment and a medium, and the pelvic floor muscle repairing instrument comprises a main body part which is used for being inserted into or placed in a part corresponding to pelvic floor muscle; the first electrode and the second electrode are arranged on the main body part and are used for electrically stimulating pelvic floor muscles and detecting pelvic floor muscle surface electromyogram signals after the pelvic floor muscles are electrically stimulated; the third electrode is attached to the peripheral muscle of the pelvic floor muscle during use and is used for detecting an electromyographic signal of the peripheral muscle of the pelvic floor muscle; the posture detection unit is arranged on the trunk part and is used for detecting a posture time sequence signal after the action of the trunk part is changed; the controller is electrically connected with the first electrode and the second electrode and is used for performing feature extraction on the three signals in the same time sequence, generating a fusion feature vector, determining a pelvic floor muscle training evaluation result and generating a training feedback instruction according to the pelvic floor muscle training evaluation result; the training feedback instruction is used for instructing the user to train.

The present disclosure provides a method and a system for electrical stimulation based on physiological parameter feedback regulation. The method includes: continuously acquiring action data and corresponding tremor manifestation data in daily activities of a user; calculating an average tremor level of the user based on the tremor manifestations; identifying a plurality of actions exhibiting tremor manifestations deviating from the average tremor level, and constructing an action set; constructing a continuous action sequence based on the action set; and guiding the user to execute the continuous action sequence while respectively applying electrical nerve stimulation with a plurality of candidate stimulation parameter sets, determining a first electrical stimulation parameter set that satisfies the conditions that the tremor level of the Category I actions decreases, and the tremor level of the Category II actions does not rise, and performing subsequent electrical stimulation using the first electrical stimulation parameter set.

The invention provides a hand rehabilitation training glove and system based on electromyographic signal guidance and pressure feedback, and the glove comprises a flexible glove main body which is made of an elastic material, is designed to fit the anatomical structure of a human hand, and is used for collecting bioelectrical signals generated by the remaining hand and forearm muscles of a patient when the patient actively intends to generate power; the embedded signal processing module is used for carrying out amplification, filtering, noise reduction and analog-to-digital conversion processing on the collected original electromyographic signals; and the main control unit is used for calculating time domain and frequency domain characteristic values of the electromyographic signals and identifying the motion intention of the patient based on a preset threshold value or an adaptive algorithm. Weak electromyographic signals are collected and processed in a high-precision mode and immediately converted into local touch pressure feedback corresponding to the functions of the weak electromyographic signals, neural pathway connection between the cerebral cortex and target muscles is enhanced, training interestingness and immersion and compliance of a patient are remarkably improved, and the training effect is improved. And key power is provided for continuous long-term rehabilitation training.

The invention relates to the technical field of intelligent medical assistance, in particular to a skin disease treatment electrode positioning system based on potential distribution. The system comprises a potential gradient severe region identification module, a lesion minimum surrounding region identification module, a similar potential region grouping module, an optimal electrode position prediction module, an electric field distribution calculation module, a sweat gland dense region identification module, an optimal electrode placement point screening module, an enhanced feature generation module and a final electrode position determination module. By fusing multi-source information such as skin surface potential distribution, lesion geometric characteristics, tissue conductivity, historical treatment data and the like, systematic optimization is performed on electrode positioning in skin disease treatment, the effectiveness of electrode stimulation is maximized on the premise of ensuring the treatment safety, and the treatment efficiency is improved. An accurate electrode placement scheme is provided for treatment of different types of skin diseases, and the method is suitable for accurate determination of the electrode placement position in electrical stimulation treatment.

An electrical stimulation device for modulating a blood-brain barrier (BBB) of a subject includes at least one electrode configured to delivery electrical stimulation to the subject to stimulate a sphenopalatine ganglion (SPG) of the subject, and a control unit in communication with the at least one electrode. The control unit generates a first electrical stimulation signal to the at least one electrode to apply a first electrical stimulation to the subject to stimulate a sphenopalatine ganglion (SPG) of the subject thereby increasing porosity of the BBB from an initial porosity to an increased porosity, and generate, after said first electrical stimulation signal, a second electrical stimulation signal to the at least one electrode to apply a second electrical stimulation to the subject to stimulate the SPG of the subject thereby decreasing porosity of the BBB from the increased porosity to a decreased porosity that is less than the increased porosity.

A medical apparatus for a patient comprises an implantable system. The implantable system comprises a first implantable device comprising: at least one implantable functional element configured to deliver stimulation energy to tissue of the patient; and an implantable controller configured to provide a stimulation waveform to the at least one implantable functional element, the stimulation waveform comprising one or more stimulation parameters. The apparatus is configured to randomly vary at least one of the one or more stimulation parameters. Methods of providing stimulation energy with randomly varying stimulation parameters are also provided.

Embodiments of the present invention disclose a cosmetic applicator head, designed for controlled dispensing of cosmetic liquids while integrating stimulation elements for enhanced skin care treatments. The applicator head comprises a main body with a mounting end configured for secure attachment to a cosmetic container, ensuring fluid communication through a liquid discharge channel. The smearing end includes a smearing surface for applying cosmetic liquid, a first surface housing at least one stimulation element, and a second surface featuring multiple convex columns for skin contact, massage, exfoliation, or cleansing. The cosmetic applicator head in some embodiments features a rotatable coupling mechanism between a connecting portion and the main body, enabling adjustable liquid flow regulation.

The invention discloses an acupuncture intervention method after a pancreatic cancer operation, and aims to solve the problem that autonomic nerve regulation based on heart rate variability in an acupuncture stimulation closed loop is difficult to objectize and safely optimize. Heart rate variability time-frequency and time-domain features and respiratory coherence are extracted based on synchronous compression wavelets, a reliability score is generated, short-time heart rate variability and uncertainty are predicted through a neural state space model, a hierarchical control barrier function is generated through a context gating network, a safe MPC is constructed, and real-time quadratic programming solution is carried out. The heart rate variability enters the target domain and the stimulation parameter change rate and the energy consumption are reduced under the condition that safety constraints such as current, pulse width, charge quantity and impedance are met by combining safety verification and self-adaptive updating, and the reliability and the robustness of closed-loop control are improved.

The system includes a processor that works with a full-body fitting garment equipped with internal sensors and low-frequency pads. It collects biometric data, connects wirelessly to an external device via a control unit, and uses an AI module to visualize the user's relaxation state. Based on this, it generates instructions to optimize relaxation and controls the pads accordingly.

The pulse and heating gasket comprises inner-layer cloth, an inner-layer adhesive film, an energy conducting film, an FPC circuit board, a middle-layer adhesive film, a battery, an outer-layer adhesive film and outer-layer cloth, the FPC circuit board comprises a pulse unit and a heating unit, and the pulse unit is covered in the energy conducting film; the FPC circuit board is arranged between the inner-layer adhesive film and the middle-layer adhesive film, and the energy conducting film penetrates through the inner-layer adhesive film and the inner-layer cloth to the outside of the inner-layer cloth; the battery is arranged between the middle-layer adhesive film and the outer-layer adhesive film, the outer-layer adhesive film is connected with the outer-layer cloth, and the inner-layer cloth is connected with the periphery of the outer-layer cloth, during application, the pulse unit generates a pulse loop, the heating unit generates a heating effect, and the energy conducting film transmits the pulse loop and the heating effect to a human body; the inner layer adhesive film and the middle layer adhesive film seal the FPC circuit board and the energy conducting film, and the middle layer adhesive film and the outer layer adhesive film seal the battery, so that the waterproof function is achieved. Therefore, the design can be washed by water, and is clean and sanitary.

The invention relates to the technical field of intelligent wearing monitoring, in particular to a multifunctional head-mounted device for improving anxiety and depression symptoms in the perioperative period, which comprises a main body base, an electric treatment assembly and a power supply assembly are arranged on the main body base, extending ear hooks are arranged at two ends of the main body base, binding straps are arranged on the extending ear hooks, and a nose pad block is arranged at the bottom of the main body base. The electric treatment assembly is in signal connection with an evaluation and control system, heart rate monitoring assemblies are arranged on the extension ear hooks, and an eye movement monitoring assembly is arranged at the bottom of the main body base; a displacement monitoring assembly is arranged on the main body base, and a respiration monitoring assembly is arranged on the nose pad block. According to the invention, physiological parameter monitoring, anxiety and depression assessment and percutaneous nerve stimulation treatment functions are integrated, and multi-node fixed design and real-time dynamic data processing are combined, so that redundant steps depending on preposed medical assessment in the traditional technology are omitted, doctors can remotely and accurately adjust personalized schemes based on dynamic data, and the accuracy of diagnosis and treatment is improved. The anxiety depression intervention efficiency and reliability in the perioperative period are improved.

The present invention relates to a device for the prevention and / or treatment of fecal and / or urinary incontinence. The device may fit into a vagina. The device may include a pressure sensor and electrodes. The device may include a lateral projection on the device and / or a skin of the device. In response to intra-abdominal pressure the device may apply electrostimulation with the electrodes, for example to a vaginal mucosa.