7085results about "External electrodes" patented technology

The invention relates to the technical field of medical instruments, in particular to a high-precision time interference non-invasive brain deep electrical stimulation method, equipment and system, and solves the problems that two stimulation electrodes are used for each pair of current in traditional time interference-based non-invasive brain deep electrical stimulation, so that the current distribution is relatively dispersed, and the stimulation focusing performance is relatively poor. According to the method, high-precision 4 * 1 electrode configuration is used, two electrodes for applying a stimulation current are changed into a 4 * 1 electrode form, the flowing path of the current is effectively limited, the current is more focused, and the focusing performance of the interference current is further improved. According to the device, high-precision current control is realized through the anti-phase output circuit, the 4 * 1 voltage division circuit, the constant current source module and the impedance detection module; the system supports forward and reverse electrode position optimization, a personalized real finite element head model simulation system based on MRI data is used for guiding practical application, the focusing performance of each pair of current in a target brain region is improved, and therefore the overall stimulation precision in the target brain region is improved.

A device, including an electrode array carrier, that carries one or more electrode arrays, and a therapeutic substance such as for example an anti-inflammatory, wherein the therapeutic substance is located in at least one cavity of the carrier, the cavity having at least one of a non-uniform depth or a non-uniform width with respect to location in a direction of the depth that has an effective impact on a delivery of the therapeutic substance to a human.

The invention discloses a medical integrated module type electroacupuncture anesthesia therapeutic apparatus, and belongs to the technical field of medical apparatuses and instruments. A medical integrated module type electroacupuncture anesthesia therapeutic apparatus comprises a signal collecting and monitoring module, a main control module, a parameter self-adaptive adjusting module, a stimulation output module and a safety monitoring unit. The problems that existing current output parameters depend on manual adjustment and doctor experience, an objective quantitative basis is lacked, a real-time physiological monitoring and feedback mechanism is lacked in the treatment process, and current adjustment lags behind the state change of a patient are solved. Through a multi-parameter fusion decision algorithm and a closed-loop real-time feedback mechanism, 'experience-driven open-loop control 'of traditional electro-acupuncture equipment is upgraded to'data-driven closed-loop control', the subjectivity and hysteresis problems of manual adjustment are solved, and treatment safety and individual adaptability are greatly improved through high-precision monitoring and quick response.

A method for treating nerves in a nasal cavity starts with identifying a patient having a condition occurring outside the nasal cavity. The method then involves activating a console attached to a radiofrequency stylus, advancing a distal tip of the radiofrequency stylus into a nostril of the patient, contacting nasal mucosa lining the nasal cavity with a treatment surface of the distal tip, and delivering radiofrequency energy from one set of bipolar electrodes on the treatment surface of the distal tip to a second set of bipolar electrodes on the treatment surface, to treat at least one nerve underlying the nasal mucosa. Treating the nerve (or nerves) involves modulating activity of the nerve to ameliorate the condition occurring outside the nasal cavity.

The invention provides a tumor electric field treatment system, an electrode slice temperature detection method and an electrode slice anomaly detection method, the system comprises an electrode slice and an adapter provided with a first controller, the electrode slice comprises a plurality of electrode units and a plurality of temperature detection units, the plurality of temperature detection units are divided into a plurality of row groups and a plurality of column groups, and the first controller is connected with the adapter. The grounding ends of the temperature detection units in each row group are jointly connected to the same grounding wire, and the signal ends of the temperature detection units in each column group are connected to the same dual-purpose signal wire after being in short circuit with the corresponding electrode units; when the dual-purpose signal line is connected to the temperature sampling point, the grounding wires are sequentially conducted, so that temperature detection signals detected by the temperature detection units are sampled based on the temperature sampling point; when the dual-purpose signal line is connected to the alternating power line, alternating electric signals are transmitted to the electrode units. Therefore, the temperature of the electrode plate can be detected by using fewer conductive traces, and whether the electrode plate is abnormal or not can be judged through temperature detection.

Methods and systems for stimulation of the vagus nerve of a patient using a stimulation system is described herein. The stimulation system including a control module and at least one stimulation lead coupleable to the control module, the at least one stimulation lead including a plurality of electrodes. The method includes implanting the at least one stimulation lead percutaneously or through an opening in the carotid sheath with placement of the electrodes proximate to the vagus nerve for stimulation of the vagus nerve; implanting the control module remote from the vagus nerve; generating stimulation signals using the control module; and delivering the stimulation signals from the control module through at least one of the electrodes of the at least one stimulation lead to stimulate the vagus nerve of the patient.

The invention belongs to the technical field of medical instruments, and particularly relates to a spinal epidural ventral side double-wing-shaped stimulation electrode and motion function reconstruction system, the spinal epidural ventral side double-wing-shaped stimulation electrode and motion function reconstruction system comprises two wing panels, each wing panel comprises a flexible substrate, the flexible substrate is provided with two bifurcated preset-curvature double-wing structures; the electrode contact array is integrated on the flexible polar plate through a bonding pad; according to the double-wing-shaped flexible substrate, through a double-wing structure with a preset curvature, after being unfolded under the driving of a nickel-titanium alloy framework, the double-wing-shaped flexible substrate accurately covers a spinal cord ventral side and double-side anterior angle motor neuron pool, and the problem that a traditional single-piece / rod-shaped electrode can only cover a back side sensing area and cannot cover a back side sensing area is solved. The ventral motor neuron group cannot be directly activated; a stimulation target spot is transferred to a ventral functional core area from a dorsal non-target area for the first time, and the anatomical suitability bottleneck of motor function reconstruction is solved.

The invention relates to the technical field of acupuncture, in particular to an intelligent acupuncture point precise positioning and stimulation regulation and control system based on combination of traditional Chinese medicine and western medicine, and the system firstly collects body surface acupuncture point information of a user, analyzes sensitivity and generates visual data. The information processing module fuses the data, generates acupoint comprehensive characteristics and marks a target acupoint. And the virtual visualization module generates a virtual acupoint image and marks a target acupoint. The needling instrument massage module formulates a needling instrument pushing scheme according to acupuncture point characteristics and needling instrument parameters, and the needling instrument pushing scheme is executed by the body surface needling instrument pushing device. Meanwhile, the electrical stimulation regulation and control module generates parameters, the electrical stimulation intensity, frequency and time are controlled, and the electric acupuncture massage device is combined with body surface acupuncture massage operation to execute treatment. According to the system, accurate acupoint positioning, personalized needle pushing scheme making and electrical stimulation regulation and control are achieved, the effect and safety of needle pushing treatment are improved, and innovative technical support is provided for modernization of traditional Chinese medicine.

The invention discloses a multifunctional defibrillation electrode plate assembly, a defibrillation host and a defibrillation system. Wherein the multifunctional defibrillation electrode plate assembly is connected with the defibrillation host through the electrode plate assembly connecting terminal group, the first electrode plate assembly connecting terminal is connected with the defibrillation electrode plate, and the second electrode plate assembly connecting terminal is connected with the information component; under the condition that the electrode plate assembly connecting terminal group is connected with the defibrillation host, the defibrillation electrode plate can be connected with the defibrillation host through the first electrode plate assembly connecting terminal to realize a defibrillation and / or monitoring function, and the information component can provide information related to the defibrillation electrode plate for the defibrillation host through the second electrode plate assembly connecting terminal; and the second electrode plate assembly connecting terminal is also connected with the auxiliary sensor, so that a first preset function can be realized between the defibrillation host and the auxiliary sensor through the second electrode plate assembly connecting terminal under the condition that the electrode plate assembly connecting terminal group is connected with the defibrillation host.

The invention discloses a brain deep nerve stimulation method and system based on adaptive adjustment, and relates to the technical field of brain deep nerve regulation, and the method comprises the steps: collecting a local field potential signal of a brain deep target region of a target patient, and extracting a beta frequency band power spectrum density and a gamma frequency band phase synchronization index as neural activity characteristic parameters; determining an individual baseline value and a preset threshold value based on historical data, and outputting a stimulation adjustment trigger signal when the beta frequency band power spectral density exceeds the individual baseline value and the gamma frequency band phase synchronization index is lower than the preset threshold value; in response to the trigger signal, calculating an optimal stimulation parameter combination through a gradient descent optimization algorithm and executing nerve regulation; and monitoring the signal change after regulation and control, calculating a relative change rate and updating a threshold value. Through a two-parameter joint judgment mechanism and a threshold updating strategy, individualized adaptive adjustment of stimulation parameters is realized, and the stimulation accuracy and the treatment effect are improved.

The invention provides a tumor electric field treatment system, an electrode slice temperature detection method and an electrode slice anomaly detection method, the system comprises an alternating current signal generator, an electrode slice and a controller, the electrode slice comprises a plurality of electrode units and a plurality of temperature detection units, the plurality of temperature detection units are divided into a plurality of row groups and a plurality of column groups, and the plurality of electrode units are connected with the controller. The grounding ends of the temperature detection units in each row group are jointly connected to the same grounding wire, and the signal ends of the temperature detection units in each column group are connected to the same dual-purpose signal wire after being in short circuit with the corresponding electrode units; when the dual-purpose signal line is connected to the temperature sampling point, the grounding wires are sequentially conducted, so that temperature detection signals detected by the temperature detection units are sampled based on the temperature sampling point; when the dual-purpose signal line is connected to the alternating power line, alternating electric signals are transmitted to the electrode units. Therefore, the temperature of the electrode plate can be detected by using fewer conductive traces, and whether the electrode plate is abnormal or not can be judged through temperature detection.

Disclosed is a beauty treatment device that kills adipocytes by locally sucking in skin to be treated and sequentially applying a high-frequency current and a high-voltage pulse. The beauty treatment device according to the present invention comprises: a main body unit; and a suction treatment unit coupled to the main body unit and having a treatment space for applying electrical stimulation by sucking in the skin of a user, wherein the suction treatment unit comprises: a suction nozzle made of a resin material, which partitions the treatment space; and a pair of electrodes disposed inside the suction nozzle so as to face each other at a distance, and the pair of electrodes have a metal conductive layer formed by plating the surface of a resin material electrode core with a conductive metal.

The invention provides an intracranial neuron electrical stimulation system for treating epilepsy and other brain diseases involving epileptic seizure, which can immediately apply intracranial neuron electrical stimulation to the interseizure epilepsy activity in a personalized manner after detecting the interseizure epilepsy pattern each time. And the stimulation is activated by intracranial electroencephalogram (EEG) detection. The intracranial stimulation for epileptic activities in the epileptic seizure period continuously acts along with time, the forming process of an epileptic network can be blocked, the neuronal super-synchronization risk is reduced, and therefore the control effect on epileptic seizure is improved. The invention also includes the use of nerve adjustment biomarkers, thereby dynamically optimizing the detectability and providing more accurate overall assessment for the patient's treatment progress. Finally, according to the scheme, by detecting the intracranial EEG mode and the high-risk state mode (such as the epileptic state and the sudden accidental death risk in epilepsy) in the attack period, an instant alarm is given to the patient / nursing personnel, and it is ensured that safe treatment measures are taken for the patient in time.

The invention discloses a closed-loop deep brain regulation and control system for epilepsy treatment, and the system comprises an electroencephalogram signal collection module which collects neural electrophysiological signals in real time by implanting a recording electrode in a cerebral cortex or hippocampal brain area; the electroencephalogram signal real-time analysis module is used for outputting the epileptic seizure period prediction probability xi through a seven-layer full-connection neural network based on the 33-dimensional feature vector so as to realize epileptic seizure early warning; when the zeta is greater than or equal to a threshold value, the electrical stimulation regulation and control module is used for triggering electrical stimulation, filtering out a frequency band required to be regulated and controlled according to filtering, calculating and predicting electrical stimulation intensity and then correcting and outputting pulse stimulation, so that personalized electrical stimulation regulation and control are carried out on a specific frequency band, and detection is continuously carried out until the frequency band becomes normal; and the medicine intervention module is used for triggering a micro-injection pump to carry out medicine infusion through a pulse signal. According to the system, epilepsy treatment is improved from empirical parameter adjustment to accurate regulation and control based on real-time nerve physiological signals, and a safer and more effective treatment choice is provided for a drug-refractory epilepsy patient.

The invention discloses a multi-target transcranial electrical stimulation device based on cross-regional phase-locked stimulation, and the device comprises a light electroencephalogram cap which is integrated with at least one pair of electroencephalogram signal collection electrodes located in a first brain region and used for monitoring specific neural oscillation, and is provided with electrode holes used for placing stimulation electrodes in a second brain region; a plurality of stimulating electrodes; a controller, a multi-channel stimulation module, an electroencephalogram signal processing and feedback regulation and control module and a communication module are arranged in the control box; the electroencephalogram signal module is configured to detect the phase of specific neural oscillation of a first brain region in real time; the controller is configured to accurately control the time or phase of stimulation (such as transcranial alternating current stimulation or pulse stimulation) output by the multi-channel stimulation module in the second brain region based on the detected real-time phase information, and cross-region phase-locked stimulation is achieved. The device is suitable for personalized nerve regulation and control application in a family environment while remarkably simplifying user operation, reducing cost and improving comfort and portability.

One aspect of the present disclosure relates to a system for treating obstructive sleep apnea in a subject. The system can include a power source and a neuromuscular stimulator in electrical communications with the power source. The neuromuscular stimulator can include a controller and at least one electrode. The controller can be configured to receive certain power and stimulation parameters associated with a therapy signal from the power source. The at least one electrode can be configured to deliver the therapy signal to a target tissue associated with control of a posterior base of the tongue of the subject.

A cuff lead arrangement includes a first cuff lead having a first cuff body; first stimulation emitters (for example, electrodes) disposed on an interior surface of the first cuff body; a first lead body coupled to the first cuff body; first conductors electrically coupled to the first stimulation emitters and extending along the first lead body; and at least one first connection element. The cuff lead arrangement further includes a second cuff lead having a second cuff body; second stimulation emitters disposed on an interior surface of the second cuff body; a second lead body coupled to the second cuff body; second conductors electrically coupled to the second stimulation emitters and extending along the second lead body; and at least one second female connection element configured to receive the at least one first male connection element to conjoin the first cuff lead to the second cuff lead.

To provide a system for transmitting blood pressure reduction electrical stimulation to the heart of a patient capable of determining a desirable AV delay.SOLUTION: The atrium is paced and the ventricle is paced with a given (arbitrary) delay to obtain a desired blood pressure change. Then, the atrium is sensed, the ventricle is paced, the blood pressure change is observed, and the resulting blood pressure change is compared with the paced-atrium-paced-ventricle desired blood pressure change. In the case where the blood pressure changes are not substantially equal, the timing of the sensed-atrium-paced-ventricle stimulation is adjusted on the basis of the comparison. The new modified resulting blood pressure change is observed, and the modified blood pressure change is compared with the paced-atrium-paced-ventricle desired blood pressure change. Adjustment and observation may be repeated until the timing of the sensed-atrium-paced-ventricle stimulation achieves the same blood pressure change as the desired blood pressure change of the paced-atrium-paced-ventricle stimulation.SELECTED DRAWING: Figure 9

A medical apparatus for a patient comprises an external system and an implantable system. The external system is configured to transmit one or more transmission signals, each transmission signal comprising at least power or data. The implantable system is configured to receive the one or more transmission signals from the external system, and to deliver stimulation energy to the patient. Methods of delivering stimulation energy are also provided.

Obstructive sleep apnea from blockage of the upper airway can result in significant health issues. Described herein is an intelligent personalized closed loop neuromodulation system and methods to prevent backwards movement of the genioglossus muscle through stimulation of certain branches of the hypoglossal nerve and muscle motor points, by using muscle feedback from electromyogram sensors to provide optimal stimulus. Alternative embodiments to treat neuropathic pain and urinary dysfunction are enclosed.

The invention provides a tumor electric field treatment system, an electrode slice temperature detection method and an electrode slice anomaly detection method, the system comprises an electrode slice and an adapter provided with a first controller, the electrode slice comprises a plurality of electrode units and a plurality of temperature detection units, the plurality of temperature detection units are divided into a plurality of row groups and a plurality of column groups, and the first controller is connected with the adapter. The grounding ends of the temperature detection units in each row group are jointly connected to the same grounding wire, and the signal ends of the temperature detection units in each column group are connected to the same dual-purpose signal wire after being in short circuit with the corresponding electrode units; when the dual-purpose signal line is connected to the temperature sampling point, the grounding wires are sequentially conducted, so that temperature detection signals detected by the temperature detection units are sampled based on the temperature sampling point; when the dual-purpose signal line is connected to the alternating power line, alternating electric signals are transmitted to the electrode units. Therefore, the temperature of the electrode plate can be detected by using fewer conductive traces, and whether the electrode plate is abnormal or not can be judged through temperature detection.

Described herein are electrical muscle stimulation (EMS) apparatuses (e.g., devices and systems, including suits, controls, etc.) having enhanced electrodes. These EMS apparatuses may have wettable electrical contacts that are adapted for reliable and easy use by the wearer of the suit (e.g., in an at-home or studio setting). Also described herein are EMS apparatuses configured to enhance the safety of operation and effectiveness of EMS.

The present invention provides systems, methods, and devices for electroporation-based therapies (EBTs). Embodiments provide patient-specific treatment protocols derived by the numerical modeling of 3D reconstructions of target tissue from images taken of the tissue, and optionally accounting for one or more of physical constraints or dynamic tissue properties. The present invention further relates to systems, methods, and devices for delivering bipolar electric pulses for irreversible electroporation exhibiting reduced or no damage to tissue typically associated with an EBT-induced excessive charge delivered to the tissue.

High-frequency irreversible electroporation (H-FIRE) is a tissue ablation modality employing bursts of electrical pulses in a positive phase-interphase delay-negative phase-interpulse delay pattern. Despite accumulating evidence suggesting the significance of these delays, their effects on therapeutic outcomes from clinically-relevant H-FIRE waveforms have not been studied extensively. The present invention provides methods of pulse delivery, including delays, that mitigate bubble formation and / or minimize the risk of arcing, such as due to the presence of bubbles, and / or minimize muscle stimulation are described herein.

A medical monitoring system comprises a wearable garment incorporating multiple physiological sensors for real-time patient monitoring. The garment integrates an embedded processing unit that receives sensor data and transmits it wirelessly to a base station or remote server. A multi-modal physiological signal processing unit analyses the data to generate composite physiological indices, including metabolic rate, work of breathing, and fall risk assessments. The garment includes optional monitoring features such as transcutaneous carbon dioxide measurement, electrocardiography, pulse oximetry, blood pressure monitoring, and accelerometer - gyroscope-based motion tracking. The system provides early-warning alerts for clinical deterioration, enabling proactive therapeutic interventions. A wireless communication module ensures real-time data transmission, supporting remote monitoring and integration with hospital networks. The garment's modular design allows for non-invasive physiological assessment while maintaining patient mobility, making it suitable for critical care, ambulatory monitoring, and telemedicine applications.

Methods and systems for spinal cord stimulation (SCS) are disclosed. The methods and systems involve the use of electrode leads implanted within the spine of a patient to record nerve responses induced by a stimulus. The disclosed neural responses differ in various aspects from the electrical responses previously measured in the SCS context, such as stimulation artifacts and evoked compound action potentials (ECAPs). The disclosed neural responses typically occur at a later time after inducing the stimulation pulse. Another significant feature is that when the frequency of evoked stimulation is ultra-low, such as about 10 Hz or less, the disclosed neural response is most significantly observed at a consistent, relatively constant amplitude as a whole. The disclosed methods and systems may use these neural responses as indications of pain, treatment, and / or another clinically relevant dimension to guide / confirm stimulation placement, as well as feedback control for stimulation parameters.

Methods and apparatuses are described for modulating multiple integrated neural networks to alter composite sensory processes, such as audition or hearing. These methods and apparatuses may be used for therapeutic and non-therapeutic uses, including enhancing entertainment and communication, by providing a cranio-cervical tuning apparatus worn in or around the outer ear or auricle. These methods and apparatuses may include functional neurosensory bias for neurosensory scrambling neuromodulation to influence composite or multi-modal sensory processes.

The invention discloses a nerve regulation and control intervention system based on time domain interference electrical stimulation, and the system comprises a magnetic resonance image registration module which receives and registers an imported magnetic resonance image, and obtains a to-be-processed MRI image; the head model tissue segmentation module is used for performing head model tissue segmentation on the to-be-processed MRI image; the stimulation simulation module is used for performing stimulation simulation based on the tissue segmentation structure to obtain a front lead field matrix; the intervention coordinate selection module is used for determining a target brain region corresponding to a target spot brain region coordinate position needing stimulation intervention and putting the target brain region into a running sequence; the electrode position arrangement optimization module is used for verifying, optimizing and finely adjusting the electric field intensity of the target brain region under different electrode arrangement schemes to obtain an electrode configuration parameter result and displaying the electrode configuration parameter result; the parameter importing module is used for receiving the selected electrode configuration parameters and imported preset electrical stimulation parameters; and the electrical stimulation module is used for performing electrical stimulation on the target brain region of the target object. According to the application, the accuracy and the effectiveness of nerve regulation and control treatment can be realized.

Described herein are systems, devices, and methods for delivering enhanced stimulation to provide therapy for a patient. A neurostimulation system may include an implantable stimulation device, a base station, and an external device. The external device may include a first antenna for communicating with the implantable device, and a second antenna for receiving power from the base station. Additionally, the external device may have one or more shielding layers between the first and second antennae. A method for reprogramming a neurostimulation system may include receiving data at a base station via a remote connection, transferring the data from the base station to an external device via a location connection, and instructing an implantable stimulation device to stimulation tissue of a patient using the data.

Systems, devices, and methods for neurostimulation using a combination of implantable and external devices to treat pain are disclosed.