77 results about "Coronary sinus" patented technology

Devices, systems, and methods for causing retrograde oxygenated blood flow in at least a portion of the venous system of the myocardium are disclosed. Devices and methods include a method for causing retrograde oxygenated blood flow in at least a portion of the venous system of the myocardium, the method comprising: implanting a variable occluder in a coronary sinus region proximate a left atrium, wherein the variable occluder is configured to gradually increase a level of blood flow restriction over a period of days to enable a venous system of the myocardium to compensate for increased pressure caused by the gradual increase in the level of blood flow restriction; and following venous system compensation, shunting oxygenated blood flow into the coronary sinus to cause retrograde flow of oxygenated blood in at least a portion of the venous system of the myocardium to thereby enable revascularization of the myocardium.

The invention belongs to the technical field of pacemaker lead implantation, and provides an AI simulation guidance pacemaker lead implantation system, which comprises a data acquisition and preprocessing module for collecting and processing medical record comprehensive data of a patient through a multi-modal data fusion unit; according to the invention, the cardiac cavity structure of a patient can be accurately simulated and accurate anatomical information is provided for lead implantation through multi-modal data such as electrocardiogram, various imaging data and the like in combination with advanced image segmentation and registration algorithms, the AI simulation and prediction module plans an optimal path for a lead through a reinforcement learning algorithm, and the accuracy of lead implantation is improved. The method has important significance for searching coronary sinus ostii and selecting target veins, the stability of the lead and the success rate of implantation are ensured, the real-time guidance and feedback module can adjust the advancing direction and speed of the lead in real time in an operation, deviation caused by manual operation is reduced, and the operation efficiency is improved. And the postoperative evaluation and optimization module can perform quantitative analysis on the implantation effect and feed data back to the AI model, so that the system performance is further optimized.

A method of reducing left atrial pressure is provided for treating diastolic heart failure. A puncture catheter is advanced into a coronary sinus for creating an opening in a wall between the coronary sinus and a left atrium of a heart. A cauterizing tool may be used to create a controlled scarring pattern in the tissue along the opening. After the opening is created, a blood flow path is provided from the left atrium to the coronary sinus for reducing blood pressure in the left atrium and thereby alleviating symptoms of heart failure. If necessary, a shunt device may be implanted within the opening to ensure that the blood flow path remains open.

A blood flow pathway is formed between a left atrium and a coronary sinus for relieving elevated left atrial pressure. The treatment method includes providing first and second delivery catheters, wherein a medical device is carried by the second delivery catheter. A side outlet opening of the first delivery catheter is positioned within the coronary sinus and oriented toward a left atrium. An anchor on the first delivery catheter contacts an inner surface of the coronary sinus for stabilization. A distal portion of the second delivery catheter is advanced through the side outlet opening. A puncture component is then passed through a target wall portion for creating the blood flow pathway. The medical device is positioned in the opening.

Provided in the present invention is a coronary sinus balloon counterpulsation catheter, comprising a catheter body and a balloon. The catheter body is provided with a first channel and a second channel that extend through the catheter body along the axial direction thereof. The first channel is eccentric to the catheter body. A cross-section of the second channel comprises a first contour line and a second contour line. The first contour line is at least a part of a first circle. The second contour line is at least a part of a second circle. The first contour line is closer to the first channel than the second contour line, and concave sides of the first contour line and the second contour line both face the first channel. The width of the second channel satisfies a predetermined relationship. The balloon is in sealed connection with a distal outer peripheral surface of the catheter body and is in communication with the second channel. The arrangement mode of the first channel and the second channel enables a filling liquid flowing in the second channel to have a relatively low resistance and a relatively high flow rate. In this way, the coronary sinus balloon counterpulsation catheter can use a liquid such as normal saline instead of a gas as a filling medium, thereby avoiding the occurrence of air embolism caused by balloon rupture and improving the safety of use.

A blood flow pathway is formed between a left atrium and a coronary sinus for relieving elevated left atrial pressure. The treatment method includes providing first and second delivery catheters, wherein a medical device is carried by the second delivery catheter. A side outlet opening of the first delivery catheter is positioned within the coronary sinus and oriented toward a left atrium. An anchor on the first delivery catheter contacts an inner surface of the coronary sinus for stabilization. A distal portion of the second delivery catheter is advanced through the side outlet opening. A puncture component is then passed through a target wall portion for creating the blood flow pathway. The medical device is positioned in the opening.

A stabilizer sleeve is disclosed for use with cardiac implantable electronic device leads. The sleeve comprises a tubular body sized to receive the lead and shaped to bias the lead toward a desired anatomical location, thereby reducing migration, dislodgement, and interference with cardiac structures. The sleeve may be introduced with the lead as a unitary assembly or added after lead placement. Various embodiments include a slitted body for expansion, radiopaque markers for visualization, detachable nose-cone tips for guidewire tracking, and antimicrobial coatings. The sleeve may be formed of polymers, alloys, or composite materials, and may include features such as texturing or anchoring projections for tissue engagement. Applications include positioning within a tricuspid valve commissure to minimize regurgitation and stabilizing left ventricular leads within branches of the coronary sinus. The device and methods described provide improved long-term stability and performance of implanted cardiac leads.

A blood flow pathway is formed between a left atrium and a coronary sinus for relieving elevated left atrial pressure. The treatment method includes providing first and second delivery catheters, wherein a medical device is carried by the second delivery catheter. A side outlet opening of the first delivery catheter is positioned within the coronary sinus and oriented toward a left atrium. An anchor on the first delivery catheter contacts an inner surface of the coronary sinus for stabilization. A distal portion of the second delivery catheter is advanced through the side outlet opening. A puncture component is then passed through a target wall portion for creating the blood flow pathway. The medical device is positioned in the opening.

The present invention discloses devices and methods for treating or repairing regurgitant heart valves such as the mitral valve and / or the tricuspid valve. Exemplary valvuloplasty devices can be placed in the coronary sinus to re-shape the mitral valve and reduce mitral regurgitation as well as tricuspid regurgitation. The present disclosure also provides improved techniques for cardiac pacing.

A device for processing cardiac signals, comprises: - a data storage (114) arranged to receive input data sets each comprising a plurality of P wave segments each associated with an electrocardiogram track and with an acquisition time window, and a plurality of coronary sinus signals associated with the same acquisition time window and having one or more activation sequence(s), - a random convolutional kernel-based extractor arranged, for a given input data set, to determine an electrocardiogram feature vector, and - a machine-learning based locator using decision trees trained on data comprising sets of electrocardiogram feature vectors labelled with a value indicating a cardiac region identifier, and arranged to receive an electrocardiogram feature vector from the random convolutional kernel-based extractor as input, and to return a cardiac region identifier as output.

A cardiac microperfusion device is disclosed that includes an integrated flow restrictor and a diverter from the left atrium to modulate flow within the blood vessel, particularly flow within the coronary sinus. Related methods and systems are also disclosed.

The present invention provides a pharmacological wearable cardioverter defibrillation system for conducting cough assisted pharmacological cardioverter defibrillation during onset of a sudden arrhythmia. The system comprises a WCD defibrillator worn by the patient, a drug mix contained either in a reservoir / pump or in an inhaler, and a miniature monitor. The drug mix in the reservoir / pump is equipped with a pump for pumping the drug mix via an indwelling catheter to the coronary sinus while the drug mix in the inhaler is inhaled directly to the lungs. When a sudden arrhythmia is detected by a sensing electrode of WCD, the following steps are carried out: prompting the patient to take the drug mix, prompting the patient to start forceful coughing, and delivering electric shock(s) under either one of the two circumstances that the patient is unable to start coughing or the arrhythmia is not terminated.

To provide a method and a system for signal processing.SOLUTION: A method is provided. The method is implemented by a device orientation engine being executed by one or two or more processors. The method includes determining a movement between each group of electrodes of a catheter to provide movements, and determining a total movement of electrodes of the catheter. The method also includes removing a standard component from the movements and the total movement and outputting a movement indication for the catheter on the basis of the movements and the total movement with the standard component.SELECTED DRAWING: Figure 1

The utility model provides a coronary sinus constriction system and a conveying device thereof, the conveying device comprises a line and a conveying mechanism, the line is used for penetrating and winding on a near-end opening along the circumferential direction of the near-end opening of the coronary sinus constriction device, and the conveying mechanism is connected with the line; the conveying mechanism can control the line to be separated from the near-end opening, or the conveying mechanism is controlled to be separated from the line, or the conveying mechanism is provided with a first catheter, the first catheter is provided with a first hollow channel, and the two ends of the line penetrate into the first hollow channel from the far end of the first catheter and penetrate out of the first hollow channel from the near end of the first catheter; the wire is separated from the proximal opening. The coronary sinus constriction system comprises the conveying device, and the conveying device can load, convey, recycle and release the coronary sinus constriction device.

A method and devices for relieving pressure in the left atrium of a patient's heart is disclosed. The method includes using an ablative catheter in a minimally invasive procedure to prepare an opening from the coronary sinus into a left atrium of the patient's heart. Once the opening is prepared, the opening may be enlarged by a technique such as expanding a balloon within the opening. A stent is then placed within the coronary sinus of the patient, with a transverse portion expanding within the opening, allowing blood to flow from the left atrium to the coronary sinus and then to the right atrium. Pressure within the left atrium is thus relieved.

A system for providing for a cardiac resynchronization therapy comprises an implantable medical device (1) comprising a generator device (10) having a processing circuitry (100) for controlling operation of the generator device (10). The implantable medical device (1) is configured to be selectively connected to a left-ventricular coronary sinus electrode lead (12) configured for implantation on the left ventricle (LV) through the coronary sinus (CS) or to a left bundle branch electrode lead (13) configured for implantation on the cardiac septum (M) to engage with the conductive structure of the left bundle branch (LBB). A configuration unit (2, 4) has a user interface (20) to modify a configuration of the implantable medical device (1). The user interface (20) is user-actuatable to select a first mode or a second mode out of at least two modes for configuring the implantable medical device (1), wherein in the first mode a first set of parameters is pre-selected or user-selectable for configuring the implantable medical device (1) to function with the left-ventricular coronary sinus electrode lead (12) and in the second mode a second set of parameters is pre-selected or user-selectable for configuring the implantable medical device (1) to function with the left bundle branch electrode lead (13).

This application relates to a coronary sinus and left atrium shunt system, belonging to the field of medical device technology. The system described in this application, by setting up a puncture component and a shunt component including a cutter, allows for the cutting of a portion of myocardial tissue between the coronary sinus and the left atrium, forming a shunt orifice. This establishes a shunt channel between the coronary sinus and the left atrium, effectively avoiding the embolism risk associated with atrial septal shunts and improving coronary artery blood perfusion, potentially benefiting myocardial recovery.

Devices, systems, and methods for causing retrograde oxygenated blood flow in at least a portion of the venous system of the myocardium are disclosed. Devices and methods include a method for causing retrograde oxygenated blood flow in at least a portion of the venous system of the myocardium, the method comprising: implanting a variable occluder in a coronary sinus region proximate a left atrium, wherein the variable occluder is configured to gradually increase a level of blood flow restriction over a period of days to enable a venous system of the myocardium to compensate for increased pressure caused by the gradual increase in the level of blood flow restriction; and following venous system compensation, shunting oxygenated blood flow into the coronary sinus to cause retrograde flow of oxygenated blood in at least a portion of the venous system of the myocardium to thereby enable revascularization of the myocardium.

The invention discloses a device and method for removing a contrast agent in heart local blood, and relates to the field of medical treatment, the removing device comprises a suction catheter, a power pump, a filter assembly and a backflow catheter which are connected in sequence; the coronary artery of the heart body is communicated with the angiographic catheter, the coronary sinus of the heart body is communicated with the suction catheter, the femoral vein or other deep veins of a human body are communicated with the backflow catheter, and the area between the coronary artery and the coronary sinus is a contrast agent delivery area; wherein the filtering assembly is used for removing a contrast agent in blood. When the contrast agent in the blood is removed, the blood containing the contrast agent is pumped out of the heart body through the suction catheter by the power pump, then the contrast agent contained in the blood is removed through the filtering assembly, and then the blood without the contrast agent is conveyed into the human body again through the femoral vein or other deep veins by the backflow catheter. By means of the circulating conveying mode, on one hand, contrast agents in blood can be removed, and on the other hand, excessive blood loss of a patient can be avoided.

The present invention provides a stable coronary sinus catheter system, the stable coronary sinus catheter system having a proximal segment and a distal segment with a shape memory portion, and a tip distal to the shape memory portion. A handle having a body, a tip deflection actuator, a shape memory portion deployment actuator, and an axis. The tip is in line with the axis, and the tip deflection actuator is in a first position. When the tip deflection actuator is in a second position, the tip deflects and is misaligned with the axis. A third position is a delivery configuration in which the shape memory portion and the tip are in line with the axis. The shape memory portion deployment actuator is in a first position. When the shape memory portion deployment actuator is in a second position, the deployment configuration allows the shape memory portion to form a predetermined shape conforming to the shape of the coronary sinus.

A method includes, during arrhythmia occurrence, acquiring multiple sets of reference coronary sinus electrophysiological (CS-EP) signals with a first catheter in coronary sinus (CS) of a heart of a patient, while measuring multiple respective reference CS locations of the first catheter. One or more intra-cardiac electrophysiological (IC-EP) signals are acquired with a second catheter located in a cardiac chamber of the heart, while acquiring actual CS-EP signal with first catheter, and while measuring an actual CS location of first catheter. Using reference CS locations, reference CS-EP signal is identified whose reference CS location is nearest to actual CS location of the first catheter. A signal-stability measure between actual CS-EP signal and identified reference CS-EP signal is estimated. If signal-stability measure is above given threshold, identified reference CS-EP is utilized to verify whether the one or more IC-EP signals acquired by the second catheter are acquired during occurrence of the arrhythmia.

Some embodiments of a system or method for treating heart tissue can include a control system and catheter device operated in a manner to intermittently occlude a heart vessel for controlled periods of time that provide redistribution of blood flow. In particular embodiments, the system and methods may be configured to monitor at least one input signal detected at a coronary sinus and thereby execute a process for determining a satisfactory time period for the occlusion of the coronary sinus. In further embodiments, after the occlusion of the coronary sinus is released, the control system can be configured to select the duration of the release phase before the starting the next occlusion cycle.

System and method for deploying a flow restriction device in patient vascular and recapturing and repositioning the flow device after full or partial deployment. Disclosed systems and methods permit confirmation of device placement, such as by measuring a pressure drop across the partially or fully deployed device in the coronary sinus before release of the device and permanent implantation.

This invention discloses a catheter assembly and a method for releasing a stent, comprising a delivery catheter for delivering a stent, and a positioning catheter for the catheter assembly. The positioning catheter includes a first end and a second end, and the delivery catheter includes an output end for delivering the stent. The first end is connected to the output end, and the end of the second end is circular, with at least three reference points distributed on the end of the second end. By fixing the catheter assembly to the coronary sinus wall outside the coronary ostium, making the end of the second end flush with the coronary ostium, and by adjusting the direction of the angiography machine, the three reference points are aligned in a straight line on the angiography machine image. The angiography machine's viewing angle, the end of the second end of the positioning catheter, and the coronary ostium are all aligned. At this point, stent delivery and release are performed. By observing the angiography machine, the stent is accurately released to the coronary ostium, avoiding excessive stent dislodgement or failure to completely cover the coronary ostium, thus ensuring accurate stent positioning.

Devices, systems, and methods for improving cardiac function are disclosed, such as a system for altering blood flow direction in a coronary sinus shunted from a left atrium, the system comprising: a tool configured to pierce and cross a first implanted occluder disposed in the coronary sinus, the tool configured to form a limited passageway through the first implanted occluder; an expander configured for delivery into the limited passageway through the first implanted occluder and for expansion within the limited passageway to compress the first implanted occluder against a wall of the coronary sinus, thereby transforming the limited passageway into a dilated opening; a retainer, configured to permanently maintain the dilated opening by holding the compressed first implanted occluder against the wall of the coronary sinus; and a second occluder configured for implantation on a downstream side of the shunt in the coronary sinus.

The present invention is a high resolution, multi-function, conformal electronics device generally having a flexible and stretchable, high-density electrode array, integrated with a catheter (e.g., balloon catheter) for mapping, ablating, pacing and sensing of cardia tissue associated with heart arrhythmias. The active sensing electrode array can acquire diagnostic information including electrical (e.g., electrograms), mechanical (e.g., strain measurements), impedance (e.g., resistance), metabolic (e.g., pH or NADH measurement) from the underlying heart tissue surface with which it is in contact. The electrode array may be designed to be of various sizes and shapes to conform to the targeted cardiac tissue architecture (e.g. atrial, ventricle, right ventricular outflow tract, coronary sinus, pulmonary veins, etc.) corresponding to the specific type of cardiac arrhythmia. The present invention can precisely locate the source of arrhythmia as described above and deliver therapy from the same electrode array. This is achieved using a capacitive sensing electrode array that can not only monitor but also deliver electrical stimulation.

A device for processing cardiac signals including a memory receiving input data sets including a plurality of P wave segments associated with an electrocardiogram track and with an acquisition time window, and a plurality of coronary sinus signals associated with the same acquisition time window and having one or more activation sequence(s). The device includes an extractor arranged, for a given input data set, to determine for at least some P wave segments of the given input data set a wave polarity profile type, at least one extremum feature. The extractor is also arranged to determine, for each group of track P wave data, a set of track P wave features comprising a polarity profile type, a data set extremum feature value for each calculated extremum feature type and an integral value determined based on the data of the corresponding group of track P wave data.

Devices, systems, and methods for causing retrograde oxygenated blood flow in at least a portion of the venous system of the myocardium are disclosed. Devices and methods include a method for causing retrograde oxygenated blood flow in at least a portion of the venous system of the myocardium, the method comprising: implanting a variable occluder in a coronary sinus region proximate a left atrium, wherein the variable occluder is configured to gradually increase a level of blood flow restriction over a period of days to enable a venous system of the myocardium to compensate for increased pressure caused by the gradual increase in the level of blood flow restriction; and following venous system compensation, shunting oxygenated blood flow into the coronary sinus to cause retrograde flow of oxygenated blood in at least a portion of the venous system of the myocardium to thereby enable revascularization of the myocardium.

A computer device for processing cardiac signals comprises: - a data storage (114) arranged to receive input data sets each comprising a plurality of P wave segments each associated with an electrocardiogram track and with an acquisition time window, and a plurality of coronary sinus signals associated with the same acquisition time window and having one or more activation sequence, - an input module comprising a plurality of classifiers, each associated with a respective atrial tachycardia class and arranged to receive an input data set, and to return a value indicating the probability that the input data set indicates an atrial tachycardia which belongs to the associated atrial tachycardia class, each classifier being further associated with a respective confusion matrix, said atrial tachycardia classes being arranged into a hierarchy made of layers each comprising one more node, each node of a given layer being connected to at least one other node in the hierarchy, only part in the layer immediately above and / or in the layer immediately below said given layer in said hierarchy, - a Bayesian engine comprising a prevalence matrix for pair of classifiers which atrial tachycardia classes are connected in said atrial tachycardia class hierarchy, arranged to receive a set of assessments comprising an atrial tachycardia class probability for each classifier, and to process said set of assessments according to the confusion matrices associated with the classifiers and according to said prevalence matrices in order to determine an updated set of assessments which maximizes the expression (I), where Z i are the updated set of assessments values, Y i are the set of assessments, YC i represents the states of the child nodes of the classifier associated with Y i in said atrial tachycardia class hierarchy, and N is the total number of classifiers, said device being arranged to receive an input data set, to process it with the input module, to derive therefrom a set of assessments provided to said Bayesian engine, and to return one or more atrial tachycardia information derived from said updated set of assessments.