43 results about "Mitral valve" patented technology

The present disclosure is directed to an external cardiac basal annuloplasty system (ECBAS or BACE-System: basal annuloplasty of the cardia externally) and methods for treatment of regurgitation of mitral and tricuspid valves. The BACE-System provides the ability to correct leakage of regurgitation of the valves with or without the use of cardiopulmonary bypass, particularly when the condition is related to dilation of the base of the heart. This ECBAS invention can be applied to the base of the heart epicardially, either to prevent further dilation or to actively reduce the size of the base of the heart.

In a surgical method for improving cardiac function, an implantable scaffold or valve support device is inserted inside a patient's heart and attached to the heart in a region adjacent to a natural mitral or other heart valve. The scaffold or valve support device defines an orifice and, after the attaching of the scaffold or valve support device to the heart, or temporary support while native valve leaflets and / or subvalvular structures are captured, a prosthetic or bio-prosthetic valve seated in the orifice, and the native valve may be retracted into the scaffold / replacement assembly to create a gasket for sealing the complex.

Adjustable annuloplasty rings for repair of a mitral or tricuspid valve which incorporate at least two separate parts that are adjustably interconnectable to create a ring the circumference of which can be changed in dimension. Rings having interconnections at spaced-apart lateral locations, which interconnections allow bidirectional movement to either shorten or lengthen the ring at either such location, afford a surgeon opportunity to make further adjustments to the dimensions of the annuloplasty ring after its initial partial securing to the heart valve tissue and thereby adjust the AP diameter of the valve being repaired. The mating interconnections at two lateral locations on the ring can be constructed so as to allow hinged movement about an axis defined by the interconnections to permit hinged movement between the two separate parts.

In a surgical method for improving cardiac function, an implantable scaffold or valve support device is inserted inside a patient's heart and attached to the heart in a region adjacent to a natural mitral or other heart valve. The scaffold or valve support device defines an orifice and, after the attaching of the scaffold or valve support device to the heart, or temporary support while native valve leaflets and / or subvalvular structures are captured, a prosthetic or bio-prosthetic valve seated in the orifice, and the native valve may be retracted into the scaffold / replacement assembly to create a gasket for sealing the complex.

The present invention describes a device and system for simulating normal and disease state cardiac functioning, including an anatomically accurate left cardiac simulator for training and medical device testing. The system and device uses pneumatically pressurized chambers to generate ventricle and atrium contractions. In conjunction with the interaction of synthetic mitral and aortic valves, the system is designed to generate pumping action that produces accurate volume fractions and pressure gradients of pulsatile flow, duplicating that of a human heart. Through the use of a remote handheld electronic controller and manual adjustments from a main control panel, the air pressure level, fluidic pressure, and heart rate is controlled to induce contractions that simulate a wide variety of heart conditions ranging from normal heart function to severely diseased or injured heart conditions.

A first surgical retractor (302) according to the invention includes a handle (308) that defines an axis (320) and has first and second ends. A retractor blade (306) is secured to the second end of the handle. The blade is of a size and shape to engage the mitral valve of a heart so as to be able to retract the mitral valve and adjacent tissues. A second retractor (304) according to the invention has a relatively narrow, elongate blade (352) that can extend deep into the heart to engage the heart in the region of the atrial appendage so as to be able to retract the atrium and expose the pulmonary veins. The retractors are especially adapted to perform an atrial fibrillation surgical procedure.

Procedures may be performed on the heart after the installation of a mitral valve fixation device. In order to prepare the heart for such procedures, the fixation device may be removed or disabled in minimally invasive ways (e.g., through an endovascular procedure), without requiring open access to the heart. The fixation device may be partitioned so that one portion may remain attached to each leaflet of the mitral valve. In another example, the leaflets may be cut along the edges of the distal element(s) of the fixation device, so as to cut the fixation device from the leaflet(s). Systems and devices for performing such procedures endovascularly are disclosed. Fixation devices with improved access to a release harness are also disclosed.

The present invention describes a device and system for simulating normal and disease state cardiac functioning, including an anatomically accurate left cardiac simulator for training and medical device testing. The system and device uses pneumatically pressurized chambers to generate ventricle and atrium contractions. In conjunction with the interaction of synthetic mitral and aortic valves, the system is designed to generate pumping action that produces accurate volume fractions and pressure gradients of pulsatile flow, duplicating that of a human heart. Through the use of a remote handheld electronic controller and manual adjustments from a main control panel, the air pressure level, fluidic pressure, and heart rate is controlled to induce contractions that simulate a wide variety of heart conditions ranging from normal heart function to severely diseased or injured heart conditions.

The present invention describes a device and system for simulating normal and disease state cardiovascular functioning, including an anatomically accurate left cardiac simulator for training and medical device testing. The system and device uses pneumatically pressurized chambers to generate ventricle and atrium contractions. In conjunction with the interaction of synthetic valves which simulate mitral and aortic valves, the system is designed to generate pumping action that produces accurate volume fractions and pressure gradients of pulsatile flow, duplicating that of a human heart. Through the use of a control unit and sensors, one or more parameters such as flow rates, fluidic pressure, and heart rate may be automatically controlled, using feedback loop mechanisms to adjust parameters of the hydraulic system simulate a wide variety of cardiovascular conditions including normal heart function, severely diseased or injured heart conditions, and compressed vasculature, such as hardening of the arteries.

A sequentially deployed prosthetic cardiac valve includes a self-expanding frame having an atrial skirt, a ventricular skirt, and an annular region disposed therebetween. A first anterior tab is disposed on an anterior portion of the frame. A posterior tab is on a posterior portion of the self-expanding frame. The frame may be designed so that any portion may expand sequentially in any desired order. For example, a portion of the first anterior tab and a portion of the posterior tab may partially self-expand first. Next, the first anterior tab may fully self-expand before the posterior tab fully self-expands. The posterior tab may fully self-expand next followed by the ventricular skirt, or the ventricular skirt may self-expand next followed by full expansion of the posterior tab.

Percutaneous apparatus for forming a bicuspid venous valve from autologous tissue are disclosed. A multilumen catheter is disclosed that includes a delivery shaft positioned on either side of the balloon. When the balloon is inflated within the vein at a treatment location where a bicuspid valve is to be created, the delivery shafts are pressed into the wall of the vein by the inflated balloon so that exit ports in the delivery shafts are at diametrically opposed locations. The delivery shafts may than be used to deliver puncture elements through the exit ports and into the vessel wall to gain access to a subintimal layer of the vein wall. In this manner, the inventive multilumen catheter aids in making properly positioned flaps of venous tissue for creating a bicuspid venous valve from autologous tissue.

Disclosed are a device and a system for simulating normal and disease state cardiovascular functioning, the device including an anatomically accurate cardiac simulator for training and medical device testing. The system and the device use pneumatically pressurized chambers to generate ventricle and atrium contractions. In conjunction with the interaction of synthetic valves, which simulate mitral and aortic valves, the system is designed to generate pumping action that produces accurate volume fractions and pressure gradients of pulsatile flow, duplicating that of a human heart. Through the use of a control unit and sensors, one or more parameters, such as flow rates, fluidic pressure, and heart rate, may be automatically controlled, using feedback loop mechanisms to adjust parameters of the hydraulic system to simulate a wide variety of cardiovascular conditions including normal heart function, severely diseased or injured heart conditions, and compressed vasculature, such as hardening of the arteries.

Embodiments of prosthetic valve frames for implantation within a native mitral valve can include a main body portion, and first and second radially extending flanges coupled to the main body portion. The flanges can be coupled to the main body such that the flanges are spaced father apart from one another when the main body portion is in a crimped configuration than when the main body portion is in an expanded configuration. Associated delivery systems and methods of delivery are provided.

A sequentially deployable prosthetic heart valve includes a self-expanding frame having an atrial skirt, a ventricular skirt, and an annular region disposed therebetween. The first front ear is positioned on the front of the frame. The rear ears are located on the rear of the self-expanding frame. The frame can be designed such that any portion can be expanded sequentially in any desired order. For example, a portion of the first front ear and a portion of the rear ear may initially partially self-expand. Next, the first anterior ear can fully self-expand before the posterior ear fully self-expands. The posterior ligaments may then be fully self-expanding, followed by self-expanding of the ventricular skirt; or the ventricular skirt may be self-expanding, followed by full expansion of the posterior ligaments.

A method for operating an implantable medical device to obtain substantially synchronized closure of the mitral and tricuspid valves based on sensed heart sounds includes sensing an acoustic energy; producing signals indicative of heart sounds of the heart of the patient over predetermined periods of a cardiac cycle during successive cardiac cycles; calculating a pulse width of such a signal; and iteratively controlling a delivery of the ventricular pacing pulses based on calculated pulse widths of successive heart sound signals to identify an RV interval or VV interval that causes a substantially synchronized closure of the mitral and tricuspid valve. A medical device for optimizing an RV interval or VV interval based on sensed heart sounds implements such a method and a computer readable medium encoded with instructions causes a computer to perform such a method.

Systems (100) and methods are provided for repairing a heart valve, such as a mitral, tricuspid or aortic valve, using an adjustable and removable implant (102) that can be delivered to the heart through the apex in a simplified and non-invasive manner. The implant can include a prosthetic valve portion (106) coupled to a proximal end of a shaft, and an anchor portion (110) coupled to a distal endof the shaft. The prosthetic valve can be suspended within an opening of the heart valve while the anchor portion is affixed to the apex of the heart. When the implant is deployed, a distance betweenthe prosthetic valve portion and the anchor portion can be adjusted, and / or the implant or a portion thereof can be rotated to thereby change the position of the prosthetic valve within the heart valve. This can allow correcting for post-implantation movements of the implant to mitigate potential complications.

The invention relates to a valve clip. The valve clip includes a first valve clip and a second valve clip; the first valve clip is woven by titanium nickel alloy wires and includes a first clip body in an annular opening structure; the bottom inside the first clip body is connected to a steel cable structure; the second valve clip is made of stainless steel and includes a second clip body, two fixing supports, a fixing ring and a hardening pipe; the fixing ring is in a circular structure and fixedly connected to the bottom of the second clip body; the front ends of the fixing supports are respectively and fixedly connected to the end section of the second clip body, and the tail ends of the fixing supports are fixedly connected to the central position at the bottom of the fixing ring; andthe hardening pipe is arranged in the bottom of the second clip body and between the two fixing supports. The advantages of the valve clip are as follows: interventional therapy can be performed on the patients with mitral, tricuspid and aortic insufficiency in valvular heart diseases; the valve clip is simple in operation, small in trauma, fast in recovery and wide in indication.

Anchor assemblies for endovascular introduction and implantation for tethering a replacement heart valve to a cardiac wall. An anchor delivery system introduces the assembly. The anchor may be either implanted with a tether connected thereto or implanted and then connected to a tether. If the latter, a tether assembly is mounted to the implanted anchor to connect the anchor to the valve. The anchors may be implanted into any cardiac wall including the interventricular septum or the epicardial space and the valve may replace the mitral or tricuspid valve.