24 results about "Venous Valves" patented technology

A catheter for forming a fistula between two vessels. The catheter comprises a catheter body having a longitudinal axis, an electrode extending radially from the catheter body for contacting a vessel wall and forming the fistula, and a cutting unit disposed proximally or distally of the electrode for cutting a venous valve.

A DVT prevention and / or mitigation device includes a wearable band having an inflatable bladder with an inflatable portion. When the wearable band is disposed about a user's leg, a majority of the inflatable portion of the inflatable bladder is positionable between the user's knee and a midpoint of the user's gastrocnemius muscle. The inflatable bladder is also inflatable to apply pressure to a portion of the user's gastrocnemius muscle, and a source of compressed air is coupled to the wearable band to deliver continuous compression cycles to the inflatable bladder at a frequency of at least 3 cycles per minute, each compression cycle having a compression period and a peak inflation pressure to induce cyclic flow in the user's venous valve sinuses from each successive inflation.

The invention discloses a method and equipment for monitoring lower limb vein deformation and blood flow based on an M-type ultrasonic technology, and the method comprises the steps: carrying out the M-type ultrasonic scanning of the lower limb skin of a user in a motion state in a preset sampling line direction through a flexible patch type ultrasonic probe; based on a preset grayscale signal gradient condition and a region-of-interest extraction condition, converting the scanned M-type ultrasonic image into a grayscale image, extracting a region-of-interest from the grayscale image, marking a low-pixel line segment representing a blood vessel envelope region in the region-of-interest as a'dark line ', d-type ultrasonic waves of a flexible patch type ultrasonic probe are used for measuring an optimal sampling line of a dark line, integration is carried out on deformation of the dark line along with time, the part between two adjacent waveforms in an obtained broken line graph is marked as a dark area, integration is carried out on changes of the edge and the internal pixel value of the dark area along with time, and the optimal sampling line of the dark line is obtained. And outputting a motion waveform image of the depth positions of the vein tube wall and the vein valve along with the time change, and calculating the vein deformation quantity of the lower limb muscles.

The invention relates to a turbine disc cavity imitated venous valve type sealing structure and a design method thereof, an axial sealing gap simulates human body vein vascular tissue, and a sealing structure assembly is located in the axial sealing gap where a disc cavity is connected with a main flow channel and comprises two rows of imitated venous valve teeth on the static disc side and two rows of imitated venous valve teeth on the rotary disc side. Furthermore, the two groups of sealing structures are matched with each other, so that the gap is gradually shrunk outwards in the radial direction, a large amount of invading gas at the joint of the disc cavity and the main flow channel is blocked, and the gas is rectified by a vortex structure and enters the main flow channel again. By means of the modeling design of the sealing assembly, fluid, namely high-temperature fuel gas, is prevented from flowing into the disc cavity in the radial direction while the fluid is guided to flow outwards in the radial direction, mixing of high-temperature invasion fuel gas and sealing cold air is enhanced, the sealing cooling efficiency of the connecting area of the disc cavity and the main flow channel is improved, and the high-temperature heat load borne by the position is reduced; and the method is of great significance to safe operation of the whole gas turbine.

This application generally relates to an transcatheter anti-reflux venous valve endoprosthesis system, including a replacement valve, a valve support frame, crimping system, and delivery system to treat patients with chronic venous insufficiency, and method for using such a system.

This application generally relates to an transcatheter anti-reflux venous valve endoprosthesis system, including a replacement valve, a valve support frame, crimping system, and delivery system to treat patients with chronic venous insufficiency, and method for using such a system.

The invention relates to a venous valve destruction structure for deep vein transcatheter arterization, and belongs to the technical field of medical devices, the venous valve destruction structure comprises a transcatheter, a venous valve knife and a limiting device, the venous valve knife is inserted in the transcatheter, the venous valve knife is provided with a moving rod, one end of the moving rod is provided with a venous valve blade with an expandable or contractible volume, and the other end of the moving rod is provided with the limiting device. The vein valve blade is retracted into the transcatheter, or the vein valve blade extends out of the transcatheter, and a handle is arranged at the other end of the moving rod; the limiting device is used for limiting the moving position of the venous valve knife and can be rotatably arranged outside the transcatheter, the venous valve knife penetrates through the interior of the limiting device, and the limiting device is connected with the moving rod through threads; the device has the advantages that the limiting device is rotated, the handle is controlled, the vein valve blade moves in one direction, the vein valve blade extends out of the transcatheter, and the vein valve is damaged through linear movement and rotation of the vein valve blade.

The present application discloses tissue grasping devices and related methods, particularly a clip for securing leaflets of a heart valve or venous valve, including a hub having a pair of anti-entanglement spring biased outer arms coupled to a lower end of the hub and a pair of anti-entanglement spring biased inner arms adjacent the outer arms and coupled to an upper end of the hub. A delivery catheter with a reinforcing member configured to position the valve clip proximate a target valve while the outer arms and inner arms are biased in an open position relative to one another. The delivery catheter or clip includes a suture that facilitates bailout. After the valve leaflets are positioned between the open outer arms and inner arms, the biasing force can be released to allow the clip to self-close the clip on the valve leaflets, thereby cinching and coapting the leaflets atraumatically and effectively.

A catheter for forming a fistula between two vessels. The catheter comprises a housing, an electrode disposed at least partially within the housing. The electrode comprises a distal portion, a proximal portion and an intermediate portion therebetween for contacting a vessel wall and forming the fistula. The catheter further comprises a valve destruction wire disposed at least partially within the housing for contacting and destroying a venous valve.

The present invention provides a valve material having synergistic anti-coagulation and anti-calcification functions and a preparation method therefor. The preparation method comprises the following steps: performing glutaraldehyde cross-linking treatment on an animal-derived biological valve material; immersing the treated valve material in a blocking solution containing an amine compound for 0.5-6 h, thereby blocking the remaining aldehyde groups after glutaraldehyde cross-linking; then placing the valve material into a reaction solution containing an anticoagulant and a cross-linking agent, and performing cross-linking treatment for 6-24 h at 4° C.-37° C.; and finally washing and obtaining the valve material, and storing the valve material in a mixed solvent of glutaraldehyde or isopropyl alcohol / glycerol. The method can effectively solve the problem of calcification and thrombosis caused by residual aldehyde groups in a valve material prepared by the existing method. The valve material prepared by the present method can be used as a valve material required for aortic valve, pulmonary valve, venous valve, mitral valve and tricuspid valve replacement.

The invention relates to a lower limb deep vein thrombus cleaning device, and belongs to the technical field of medical instruments. The thrombus removal device comprises a thrombus removal mesh basket assembly, the front end is inserted into a catheter in the blood flowing direction and penetrates through a vein valve and thrombus, and the thrombus removal mesh basket assembly is used for cleaning and containing the thrombus at the front end of the vein valve; the rotary telescopic assembly is arranged at the rear end of the thrombus extraction mesh basket assembly and used for controlling the thrombus extraction mesh basket assembly to stretch out, draw back and rotate in the target blood vessel so as to cut or scrape thrombus; the front end of the collecting assembly is inserted into the catheter in the blood flowing direction, abuts against the rear end of the vein valve and is used for cleaning and collecting thrombus at the front end and the rear end of the vein valve. The problem of cleaning blind areas caused by irregular outlines of the vein valve areas is effectively solved, and the thrombus cleaning device has the advantages that thrombus at the front end and the rear end of the vein valve can be cleaned at the same time, cleaning blind areas are effectively reduced, thoroughness of thrombus cleaning is improved, and thrombus residual risks are reduced.

The application provides a thrombus crushing device and a thrombus removing system. The thrombus crushing device comprises a thrombus crushing unit and a separation unit. The separation unit is connected with the proximal end of the thrombus removing head, and part of the separation unit is located between the transmission pipe and the thrombus crushing knife to shield part of the opening. The separation unit plays a role of blocking the blood vessel wall. That is, the separation unit can block the blood vessel wall and the venous valve from entering the thrombus removing head during the thrombus removing process, thereby reducing the damage. Moreover, the separation unit can separate the mural thrombus from the blood vessel wall while blocking the blood vessel wall during the thrombus removing process, thereby increasing the removing efficiency of the mural thrombus and improving the thrombus removing effect. In addition, the thrombus crushing knife, the separation unit and the thrombus removing head form a multi-layer cutting structure during the thrombus removing process, so that repeated cutting of the thrombus is realized, the thrombus crushing efficiency is improved, and the operation time is reduced. Therefore, the thrombus crushing device and the thrombus removing system provided by the application not only can protect the blood vessel wall, but also can improve the thrombus crushing efficiency and the thrombus removing effect.

The utility model relates to a guide wire conveying device which comprises a guide wire, a first sheath tube and a second sheath tube, a guide wire channel for the guide wire to penetrate through is formed in the first sheath tube, a blood drawing channel is formed in the tube wall of the first sheath tube, a blood drawing opening is formed in the far end of the first sheath tube, the blood drawing opening penetrates through the outer wall of the first sheath tube, and the blood drawing opening is communicated with the blood drawing channel. The near end of the blood drawing channel penetrates through the near end of the first sheath tube; a penetrating channel is formed in the second sheath tube, an inflation channel is formed in the tube wall of the second sheath tube, an air bag is connected to the outer side of the second sheath tube, and the inflation channel communicates with the air bag to supply air to the air bag; the first sheathing canal penetrates through the penetrating channel, and the blood drawing opening penetrates out of the far end of the second sheathing canal. When the guide wire penetrates through the vein valve, the vein valve can be controlled to be opened, so that the guide wire can pass through the vein valve in a lossless mode, it is guaranteed that the guide wire cannot damage the vein valve, and the effect of an interventional operation is improved.

The utility model relates to a guide wire conveying system which comprises a guide wire and an outer sheath tube, a guide wire channel, an inflation channel and a blood drawing channel are arranged in the outer sheath tube, an air bag is connected to the outer sheath tube, the inflation channel is communicated with the air bag, and the blood drawing channel is communicated with the air bag. The guide wire channel, the inflation channel and the blood drawing channel all extend in the extension direction of the outer sheath tube, the guide wire channel and the blood drawing channel penetrate through the two ends of the outer sheath tube, and the guide wire penetrates through the guide wire channel. When the guide wire penetrates through the vein valve, the vein valve can be controlled to be opened, so that the guide wire can pass through the vein valve in a lossless mode, it is guaranteed that the guide wire cannot damage the vein valve, and the effect of an interventional operation is improved.

Provided in the present disclosure are a prosthetic venous valve, a stent, and a prosthetic venous valve leaflet and a design method therefor, relating to the technical field of medical instruments. The stent involved in the present disclosure comprises a proximal segment support frame, a valve leaflet fixing assembly, a pocket-shaped support rod, and a distal segment support frame. The valve leaflet fixing assembly is connected between the proximal segment support frame and the distal segment support frame, and is configured for fixing the valve leaflet. A first end of the pocket-shaped support rod is connected to the proximal segment support frame, and a second end of the pocket-shaped support rod is connected to the distal segment support frame. When the stent is expanded, the pocket-shaped support rod can protrude along a radial direction of the stent in a direction away from the central axis of the stent, so as to form a pocket-shaped space on a proximal side of the valve leaflet fixing assembly.

A venous valve prosthesis for transporting a flow of body fluid in a vessel in a predetermined direction includesincludes a hollow-cylindrical support structure. A skirt is connected to the support structure and forms a closed, circumferential jacket of the support structure. The prosthesis also includes a valve leaflet arrangement with a first valve leaflet and a second valve leaflet, each being connected to the skirt. A downstream edge of the first valve leaflet and a downstream edge of the second valve leaflet are opposite to each other and configured in such a manner that in a first state of the valve leaflet arrangement they form an opening for blood to flow through in the predetermined direction and in a second state of the valve leaflet arrangement the opening is closed and to prevent a backflow of blood in a direction opposite to the predetermined direction. A ratio of the inner diameter of the support structure to its length in the predetermined direction is at most 1.

The present application provides a venous valve prosthesis, comprising a stent body and a valve; the stent body has an inner cavity, and the stent body comprises a proximal positioning part, a supporting part and a distal positioning part; the valve is connected to at least the supporting part and divides the inner cavity into a first segment and a second segment arranged from the proximal end to the distal end; the valve has a first position and a second position; the venous valve prosthesis is used for implanting into a target lumen for the target liquid to flow through; when the valve is subjected to a pressure from the target liquid pointing from the distal end to the proximal end, the valve is in the first position, so as to make the first segment and the second segment communicate to allow the target liquid to flow from the second segment into the first segment; when the valve is subjected to a pressure from the target liquid pointing from the proximal end to the second segment, the valve is in the second position, so as to make the first segment and the second segment isolated to prevent the target liquid from flowing from the first segment into the second segment. The venous valve prosthesis can be implanted into a venous vessel and replace a diseased venous valve, thereby preventing blood reflux.

This invention discloses a method for preparing a biogenic vein containing venous valves, belonging to the field of biomedical functional technology. The method includes the following steps: cutting a porcine or bovine jugular vein containing intact valves, cleaning, disinfecting, and rinsing it for later use; sequentially performing cell lysis, cell digestion, and nucleic acid digestion; then immersing it in a 1 mol / L hydroxylamine sulfate solution for heparin covalent cross-linking; and finally immersing it in a treatment solution to obtain a biogenic vein containing venous valves. The treatment solution is a PBS solution containing 4 wt% hydroxyethyl starch and 0.1 wt% polyhexamethylene biguanide. The method for preparing a biogenic vein containing venous valves provided by this invention significantly solves the technical problems of insufficient dehydration and antibacterial activity mentioned in the background art by introducing a treatment solution containing 4 wt% hydroxyethyl starch and 0.1 wt% polyhexamethylene biguanide during the preparation process. Simultaneously, the valve function of the biogenic vein is significantly improved.

The application discloses a kind of venous valve hydrogel scaffold material and its preparation method and application.This method uses polyethylene oxide and other viscoelastic non-Newtonian fluid capable of experiencing weissenberg effect as liquid soft template, when polyethylene oxide solution experiences weissenberg effect similar to valve structure, a layer of fast-crosslinking hydrogel material precursor is evenly covered on the liquid surface by spraying, so that the hydrogel is quickly crosslinked, and a venous valve hydrogel scaffold material is obtained.The application has the advantages of simple device, fast and convenient manufacturing method, adjustable venous valve scaffold material structure, etc., and can realize continuous manufacturing of venous valve hydrogel scaffold material with low cost.The application can promote the further development of valve-related physiology and pathology research.The prepared venous valve hydrogel scaffold material can realize the one-way flow function of venous valve, and can be used to construct an in-vitro venous valve model, so it has good medical application prospect.

The present application relates to a thrombectomy system, comprising a suction catheter, a blocking device and a stirring device, the suction catheter has a suction channel and a guide wire channel, the blocking device comprises a blocking catheter and a blocking device arranged at the distal end of the blocking catheter and having an open state and a folded state; the stirring device comprises a first sheath tube, a second sheath tube slidingly sleeved outside the first sheath tube, and a stirring assembly arranged at the distal end of the first sheath tube. The present application can remove a large amount of thrombus in the inferior vena cava in a relatively safe manner, protect the venous valve and the venous vessel wall, control the amount of blood loss, simplify the operation steps, shorten the operation time and reduce the hospitalization cost of the patient.

Artificial material systems that seek to mimic the basic processes of life must perform multiple complex functions including responsiveness, motion, and metabolism. Networks of programmable materials offer a pathway toward achieving these functions by altering local chemical, physical, and structural properties to enable control. We demonstrate the ability to perform multiple complex functions in a single soft elastomeric material system by reconfiguring, in situ, passive bistable fluidic diodes that are inspired by mammalian venous valves. We show how pneumo-mechanical programmability allows these silicone elastomer diode assemblies to accomplish, without rearranging the fluidic circuit, multiple functions including pumping (motion), energy storage / discharge (metabolism), logic operations (response), and signal filtering / rectification. The ability to achieve multiple functions through in situ programming may lead to the development of efficient artificial systems capable of complex functions in compact, remote applications.

The utility model provides a double-layer stent and an artificial vein valve, and relates to the technical field of artificial vein valves. The double-layer stent comprises an outer stent, an inner stent and one or more stent connecting rods, wherein the inner stent is arranged in the outer stent and used for arranging valve leaflets, and the outer stent and the inner stent are connected through the stent connecting rods. Wherein a gap is formed between the outer support and the inner support, and the minimum distance between the outer support and the inner support is larger than zero.